Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionribose phosphate diphosphokinase activity

PRPS2 PRPS1L1 PRPS1

1.70e-0651123GO:0004749
GeneOntologyMolecularFunctiondiphosphotransferase activity

PRPS2 PRPS1L1 PRPS1

3.39e-0661123GO:0016778
GeneOntologyMolecularFunctionAMP binding

PRPS2 PFKL PFKM PRPS1

5.21e-06211124GO:0016208
GeneOntologyMolecularFunctionN-acetyl-L-aspartate-L-glutamate ligase activity

RIMKLA RIMKLB

3.12e-0521122GO:0072590
GeneOntologyMolecularFunctionABC-type polyamine transporter activity

ATP13A2 ATP13A3

3.12e-0521122GO:0015417
GeneOntologyMolecularFunction6-phosphofructokinase activity

PFKL PFKM

9.32e-0531122GO:0003872
GeneOntologyMolecularFunctioncell adhesion molecule binding

SPTAN1 OBSCN UNC45A ITGAD JAML SLC3A2 MPRIP POSTN TLN1 TENM1 DIAPH3 CCS

1.37e-0459911212GO:0050839
GeneOntologyMolecularFunctionphospholipid binding

SESTD1 GAS6 OBSCN ATP13A2 PLEKHA8P1 CADPS SCARB2 TLN1 ARHGAP44 PLEKHA8 RASAL1

2.59e-0454811211GO:0005543
GeneOntologyMolecularFunctionfructose-6-phosphate binding

PFKL PFKM

3.08e-0451122GO:0070095
GeneOntologyMolecularFunctionfructose binding

PFKL PFKM

4.61e-0461122GO:0070061
GeneOntologyMolecularFunctionceramide 1-phosphate binding

PLEKHA8P1 PLEKHA8

6.43e-0471122GO:1902387
GeneOntologyMolecularFunctionceramide 1-phosphate transfer activity

PLEKHA8P1 PLEKHA8

6.43e-0471122GO:1902388
GeneOntologyMolecularFunctionphosphofructokinase activity

PFKL PFKM

6.43e-0471122GO:0008443
GeneOntologyMolecularFunctioncadherin binding

SPTAN1 OBSCN UNC45A SLC3A2 MPRIP TLN1 DIAPH3 CCS

6.54e-043391128GO:0045296
GeneOntologyMolecularFunctionphosphatidylserine binding

SESTD1 GAS6 SCARB2 TLN1

7.58e-04731124GO:0001786
GeneOntologyMolecularFunctiontransferase activity, transferring phosphorus-containing groups

HJV PRPS2 TUT7 OBSCN PFKL PFKM POLA2 TIPARP PRPS1L1 NEK4 TESK2 PEAK1 MAP2K2 PRPS1

7.66e-0493811214GO:0016772
GeneOntologyMolecularFunctionceramide transfer activity

PLEKHA8P1 PLEKHA8

8.54e-0481122GO:0120017
GeneOntologyMolecularFunctionphosphatidylinositol-4-phosphate binding

SESTD1 OBSCN PLEKHA8

1.07e-03361123GO:0070273
GeneOntologyMolecularFunctionP-type transmembrane transporter activity

ATP13A2 ATP2C2 ATP13A3

1.07e-03361123GO:0140358
GeneOntologyMolecularFunctionP-type ion transporter activity

ATP13A2 ATP2C2 ATP13A3

1.07e-03361123GO:0015662
GeneOntologyMolecularFunctionsphingolipid transfer activity

PLEKHA8P1 PLEKHA8

1.09e-0391122GO:0120016
GeneOntologyMolecularFunctionpolyamine transmembrane transporter activity

ATP13A2 ATP13A3

1.66e-03111122GO:0015203
GeneOntologyMolecularFunctionprotein homodimerization activity

PRPS2 SYNE1 WRN TRIM6 JAML SLC3A2 PDLIM4 PRPS1L1 SCARB2 TENM1 DIAPH3 PRPS1

2.07e-0381511212GO:0042803
GeneOntologyBiologicalProcess5-phosphoribose 1-diphosphate metabolic process

PRPS2 PRPS1L1 PRPS1

3.16e-0661133GO:0046391
GeneOntologyBiologicalProcess5-phosphoribose 1-diphosphate biosynthetic process

PRPS2 PRPS1L1 PRPS1

3.16e-0661133GO:0006015
GeneOntologyBiologicalProcessregulation of glucosylceramidase activity

ATP13A2 SCARB2

2.98e-0521132GO:1905123
GeneOntologyBiologicalProcesscellular response to vitamin K

GAS6 POSTN

2.98e-0521132GO:0071307
GeneOntologyCellularComponentribose phosphate diphosphokinase complex

PRPS2 PRPS1L1 PRPS1

1.57e-0651143GO:0002189
GeneOntologyCellularComponent6-phosphofructokinase complex

PFKL PFKM

8.81e-0531142GO:0005945
DomainPRPP_SYNTHASE

PRPS2 PRPS1L1 PRPS1

2.27e-0731153PS00114
DomainPRib_PP_synth_CS

PRPS2 PRPS1L1 PRPS1

2.27e-0731153IPR000842
DomainPribosyltran_N

PRPS2 PRPS1L1 PRPS1

2.25e-0651153PF13793
DomainPribosyl_synth

PRPS2 PRPS1L1 PRPS1

2.25e-0651153PF14572
DomainRib-P_diPkinase

PRPS2 PRPS1L1 PRPS1

2.25e-0651153IPR005946
DomainPribosyltran_N

PRPS2 PRPS1L1 PRPS1

2.25e-0651153IPR029099
DomainPribosyltran

PRPS2 PRPS1L1 PRPS1

3.62e-05111153PF00156
DomainATP-grasp_RimK-type

RIMKLA RIMKLB

3.76e-0521152IPR013651
DomainARHGEF5_35

ARHGEF5 ARHGEF35

3.76e-0521152PF15441
DomainARHGEF5/35_N

ARHGEF5 ARHGEF35

3.76e-0521152IPR029212
DomainRimK

RIMKLA RIMKLB

3.76e-0521152PF08443
DomainRpS6_RimK/Lys_biosynth_LsyX

RIMKLA RIMKLB

3.76e-0521152IPR004666
DomainPRTase-like

PRPS2 PRPS1L1 PRPS1

4.80e-05121153IPR029057
DomainPRibTrfase_dom

PRPS2 PRPS1L1 PRPS1

4.80e-05121153IPR000836
Domain-

PRPS2 PRPS1L1 PRPS1

4.80e-051211533.40.50.2020
Domain6-Pfructokinase_euk

PFKL PFKM

1.12e-0431152IPR009161
DomainPHOSPHOFRUCTOKINASE

PFKL PFKM

1.12e-0431152PS00433
DomainPhosphofructokinase_CS

PFKL PFKM

1.12e-0431152IPR015912
DomainPFK

PFKL PFKM

1.12e-0431152PF00365
DomainATP_PFK

PFKL PFKM

1.12e-0431152IPR022953
DomainPhosphofructokinase_dom

PFKL PFKM

1.12e-0431152IPR000023
DomainATPase_P-typ_cation-transptr_N

ATP13A2 ATP2C2 ATP13A3

2.05e-04191153IPR004014
DomainP5-ATPase

ATP13A2 ATP13A3

2.24e-0441152PF12409
DomainGLTP

PLEKHA8P1 PLEKHA8

2.24e-0441152PF08718
DomainGlycolipid_transfer_prot_dom

PLEKHA8P1 PLEKHA8

2.24e-0441152IPR014830
DomainP-type_TPase_V

ATP13A2 ATP13A3

3.71e-0451152IPR006544
DomaincEGF

GAS6 HMCN1 LTBP3

5.33e-04261153PF12662
DomaincEGF

GAS6 HMCN1 LTBP3

5.33e-04261153IPR026823
DomainPH

PLEKHG4 ARHGEF5 OBSCN MPRIP CADPS PLEKHA8 RASAL1

5.43e-042291157PF00169
DomainEGF

SELE GAS6 MEP1B HMCN1 TENM1 ASTN1 LTBP3

6.33e-042351157SM00181
DomainEGF_3

SELE GAS6 MEP1B HMCN1 TENM1 ASTN1 LTBP3

6.33e-042351157PS50026
DomainEGF-like_dom

SELE GAS6 MEP1B HMCN1 TENM1 ASTN1 LTBP3

8.89e-042491157IPR000742
DomainSPEC

SESTD1 SYNE1 SPTAN1

9.90e-04321153SM00150
DomainSpectrin/alpha-actinin

SESTD1 SYNE1 SPTAN1

9.90e-04321153IPR018159
DomainEGF_1

SELE GAS6 MEP1B HMCN1 TENM1 ASTN1 LTBP3

1.02e-032551157PS00022
DomainEGF-like_CS

SELE GAS6 MEP1B HMCN1 TENM1 ASTN1 LTBP3

1.17e-032611157IPR013032
DomainEGF_2

SELE GAS6 MEP1B HMCN1 TENM1 ASTN1 LTBP3

1.27e-032651157PS01186
DomainATPase_P-typ_cyto_domN

ATP13A2 ATP2C2 ATP13A3

1.29e-03351153IPR023299
DomainATPase_P-typ_P_site

ATP13A2 ATP2C2 ATP13A3

1.40e-03361153IPR018303
DomainP_typ_ATPase

ATP13A2 ATP2C2 ATP13A3

1.40e-03361153IPR001757
DomainATPASE_E1_E2

ATP13A2 ATP2C2 ATP13A3

1.40e-03361153PS00154
DomainATPase_P-typ_transduc_dom_A

ATP13A2 ATP2C2 ATP13A3

1.52e-03371153IPR008250
DomainE1-E2_ATPase

ATP13A2 ATP2C2 ATP13A3

1.52e-03371153PF00122
DomainPH

PLEKHG4 ARHGEF5 OBSCN MPRIP CADPS PLEKHA8 RASAL1

1.68e-032781157SM00233
DomainPH_DOMAIN

PLEKHG4 ARHGEF5 OBSCN MPRIP CADPS PLEKHA8 RASAL1

1.71e-032791157PS50003
DomainPH_domain

PLEKHG4 ARHGEF5 OBSCN MPRIP CADPS PLEKHA8 RASAL1

1.75e-032801157IPR001849
DomainGDS_CDC24_CS

PLEKHG4 ARHGEF5 OBSCN

1.77e-03391153IPR001331
DomainRho_GTPase_activation_prot

TAGAP ARHGAP17 ARHGAP44 RASAL1

2.14e-03881154IPR008936
DomainWWE

TRIP12 TIPARP

2.38e-03121152PF02825
DomainWWE-dom

TRIP12 TIPARP

2.38e-03121152IPR004170
DomainWWE

TRIP12 TIPARP

2.38e-03121152PS50918
Domain-

RIMKLA RIMKLB

2.80e-031311523.40.50.20
DomainAnk

ANKS4B CLIP4 EHMT1 KANK4 ANKRD36 POTEJ

2.89e-032281156PF00023
Domain-

PLEKHG4 ARHGEF5 OBSCN MPRIP CADPS TLN1 PLEKHA8 RASAL1

2.90e-0339111582.30.29.30
DomainATP_GRASP

RIMKLA RIMKLB

3.26e-03141152PS50975
DomainATP-grasp

RIMKLA RIMKLB

3.26e-03141152IPR011761
DomainPreATP-grasp_dom

RIMKLA RIMKLB

3.26e-03141152IPR016185
DomainBAR

ARHGAP17 ARHGAP44

3.74e-03151152SM00721
DomainBAR

ARHGAP17 ARHGAP44

3.74e-03151152PF03114
Domain-

RIMKLA RIMKLB

3.74e-031511523.30.1490.20
DomainBAR_dom

ARHGAP17 ARHGAP44

4.26e-03161152IPR004148
Domain-

ANKS4B CLIP4 EHMT1 KANK4 ANKRD36 POTEJ

4.36e-0324811561.25.40.20
DomainANK

ANKS4B CLIP4 EHMT1 KANK4 ANKRD36 POTEJ

4.62e-032511156SM00248
DomainANK_REPEAT

ANKS4B CLIP4 EHMT1 KANK4 ANKRD36 POTEJ

4.80e-032531156PS50088
DomainATPase_P-typ_cation-transptr_C

ATP2C2 ATP13A3

4.81e-03171152IPR006068
DomainCation_ATPase_C

ATP2C2 ATP13A3

4.81e-03171152PF00689
DomainPH_dom-like

PLEKHG4 ARHGEF5 OBSCN MPRIP CADPS TLN1 PLEKHA8 RASAL1

4.86e-034261158IPR011993
DomainAnkyrin_rpt-contain_dom

ANKS4B CLIP4 EHMT1 KANK4 ANKRD36 POTEJ

4.89e-032541156IPR020683
DomainANK_REP_REGION

ANKS4B CLIP4 EHMT1 KANK4 ANKRD36 POTEJ

4.89e-032541156PS50297
DomainATP_grasp_subdomain_1

RIMKLA RIMKLB

5.39e-03181152IPR013815
DomainCation_ATPase_N

ATP2C2 ATP13A3

5.39e-03181152PF00690
Domain-

RIMKLA RIMKLB

5.39e-031811523.30.470.20
DomainCation_ATPase_N

ATP13A2 ATP2C2

5.39e-03181152SM00831
DomainAnkyrin_rpt

ANKS4B CLIP4 EHMT1 KANK4 ANKRD36 POTEJ

5.67e-032621156IPR002110
DomainBAR

ARHGAP17 ARHGAP44

6.00e-03191152PS51021
DomainPRAME_family

PRAMEF7 PRAMEF8

6.00e-03191152IPR026271
PathwayKEGG_PENTOSE_PHOSPHATE_PATHWAY

PRPS2 PFKL PFKM PRPS1L1 PRPS1

3.80e-0727805M1386
PathwayREACTOME_PENTOSE_PHOSPHATE_PATHWAY

PRPS2 PRPS1L1 PRPS1

7.62e-0515803M27682
PathwayREACTOME_PENTOSE_PHOSPHATE_PATHWAY

PRPS2 PRPS1L1 PRPS1

7.62e-0515803MM15404
Pubmed

Promoter regions of the human X-linked housekeeping genes PRPS1 and PRPS2 encoding phosphoribosylpyrophosphate synthetase subunit I and II isoforms.

PRPS2 PRPS1L1 PRPS1

3.81e-08311831314091
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

DCTN2 SPTAN1 UNC45A NCAPH SLC3A2 MPRIP KMT2C PHF3 TLN1 DIAPH3 PEAK1 ZMYM4 PCM1

5.04e-085491181338280479
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

DCTN2 SYNE1 SPTAN1 PFKL PFKM MDH2 SLC3A2 MPRIP GDA NWD2 CADPS TLN1 ARHGAP44 HADHB PEAK1 PCM1 RASAL1 CACNA2D3 PRPS1

3.57e-0714311181937142655
Pubmed

Clinical associations of the genetic variants of CTLA-4, Tg, TSHR, PTPN22, PTPN12 and FCRL3 in patients with Graves' disease.

TG FCRL3 CTLA4

3.79e-075118319438904
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

MON2 PRPS2 DCTN2 PSMA2 SPTAN1 PSMC4 UNC45A PFKL PFKM POLA2 NCAPH GDA PRPF4 TLN1 MAD1L1 NUP133 CNDP2 RASAL1 PRPS1

4.59e-0714551181922863883
Pubmed

BioID Performed on Golgi Enriched Fractions Identify C10orf76 as a GBF1 Binding Protein Essential for Golgi Maintenance and Secretion.

DCTN2 UNC45A WDR11 PRPF4 TLN1 NUP133 DIAPH3 ARMH3

7.92e-07216118831519766
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

MON2 NDOR1 OBSCN ARHGAP17 ATP13A2 MPRIP KMT2C CCDC34 TLN1 ARHGAP44 MAD1L1 EHMT1 NLRC5 LTBP3 RASAL1 GAREM1

1.08e-0611051181635748872
Pubmed

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.

UBR2 DCTN2 PSMA2 SPTAN1 PSMC4 UNC45A PFKL PFKM MDH2 TRIP12 MPRIP PRPF4 PHF3 TLN1 CNDP2 HADHB MAP2K2

1.10e-0612471181727684187
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

RIMKLA ARHGEF5 SPTAN1 ARHGAP17 UNC45A TRIP12 MPRIP NEK4 PHF3 TESK2 MAD1L1 PEAK1 MAP2K2 PCM1

1.41e-068611181436931259
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

MON2 DCTN2 PSMA2 SPTAN1 PSMC4 UNC45A PFKL PFKM MDH2 NCAPH SLC3A2 SCARB2 TLN1 NUP133 ATP13A3 HADHB PCM1 PRPS1

1.77e-0614401181830833792
Pubmed

FAM46C and FNDC3A Are Multiple Myeloma Tumor Suppressors That Act in Concert to Impair Clearing of Protein Aggregates and Autophagy.

DCTN2 PSMA2 SPTAN1 PSMC4 PFKL MDH2 SLC3A2 HADHB

2.22e-06248118832963011
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

DCTN2 SYNE1 SPTAN1 PSMC4 UNC45A PFKM MDH2 SLC3A2 MPRIP WDR11 TLN1 NUP133 EHMT1 CNDP2 HADHB DIAPH3 PEAK1 PCM1

2.78e-0614871181833957083
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

UBR2 IL17REL GAS6 OBSCN E2F3 PFKL KMT2C WDR11 ARHGAP44 MAD1L1 EHMT1 CNDP2 RBM6 NLRC5 MAP2K2 SLC2A11 ZMYM4 PCM1

2.83e-0614891181828611215
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

PLEKHG4 PSMA2 SPTAN1 TUT7 PSMC4 CASP8 UNC45A PFKL PFKM NCAPH TRIP12 SLC3A2 MPRIP WDR11 TLN1 NUP133 HADHB

3.31e-0613531181729467282
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

SYNE1 PSMA2 SPTAN1 PSMC4 PCDHA8 MDH2 SLC3A2 TLN1 CNDP2 HADHB PEAK1 HYDIN PRPS1

3.81e-068071181330575818
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

DCTN2 SPTAN1 PSMC4 UNC45A PFKM NCAPH TRIP12 TLN1 MAD1L1 DIAPH3 MAP2K2

4.99e-065821181120467437
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

PRPS2 SYNE1 PSMA2 SPTAN1 PFKM MDH2 NCAPH TRIP12 SLC3A2 PRPS1L1 RFTN1 RIMKLB TENM1 HADHB DIAPH3 POTEJ PRPS1

7.66e-0614421181735575683
Pubmed

Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.

DCTN2 SPTAN1 PSMC4 MDH2 POLA2 MPRIP PRPF4 PHF3 TLN1 POTEJ

9.32e-065061181030890647
Pubmed

Insulin specifically regulates expression of liver and muscle phosphofructokinase isoforms.

PFKL PFKM

1.14e-052118229655163
Pubmed

Association of Cytotoxic T-Lymphocyte Antigen 4 (CTLA4) and Thyroglobulin (TG) Genetic Variants with Autoimmune Hypothyroidism.

TG CTLA4

1.14e-052118226963610
Pubmed

Disruption of an EHMT1-associated chromatin-modification module causes intellectual disability.

KMT2C EHMT1

1.14e-052118222726846
Pubmed

Molecular identification of N-acetylaspartylglutamate synthase and beta-citrylglutamate synthase.

RIMKLA RIMKLB

1.14e-052118220657015
Pubmed

Isozyme analysis of human polymorphonuclear leukocyte phosphofructokinase from insulin resistant individuals.

PFKL PFKM

1.14e-05211828780720
Pubmed

The predictive value of CTLA-4 and Tg polymorphisms in the recurrence of Graves' disease after antithyroid withdrawal.

TG CTLA4

1.14e-052118217526951
Pubmed

The molecular mechanism of the inherited phosphofructokinase deficiency associated with hemolysis and myopathy.

PFKL PFKM

1.14e-05211826444532
Pubmed

[Susceptibility genes for the development of autoimmune thyroid disease].

FCRL3 CTLA4

1.14e-052118217154080
Pubmed

[Increased activity of PRPP synthetase].

PRPS2 PRPS1

1.14e-052118218409517
Pubmed

In children with autoimmune thyroiditis CTLA4 and FCRL3 genes--but not PTPN22--are overexpressed when compared to adults.

FCRL3 CTLA4

1.14e-052118226994388
Pubmed

PRPS1-mediated purine biosynthesis is critical for pluripotent stem cell survival and stemness.

PRPS2 PRPS1

1.14e-052118233493137
Pubmed

Functional convergence of histone methyltransferases EHMT1 and KMT2C involved in intellectual disability and autism spectrum disorder.

KMT2C EHMT1

1.14e-052118229069077
Pubmed

The glycolytic enzyme phosphofructokinase-1 assembles into filaments.

PFKL PFKM

1.14e-052118228646105
Pubmed

Tissue-differential expression of two distinct genes for phosphoribosyl pyrophosphate synthetase and existence of the testis-specific transcript.

PRPS2 PRPS1

1.14e-05211822537655
Pubmed

Periostin promotes ectopic osteogenesis of CTLA4-modified bone marrow mesenchymal stem cells.

POSTN CTLA4

1.14e-052118228687929
Pubmed

Large-scale analysis of the human ubiquitin-related proteome.

UBR2 DCTN2 PSMA2 PSMC4 RIMKLB PRPF4 NUP133 HADHB

1.22e-05313118816196087
Pubmed

Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.

PLEKHG4 TAGAP ARHGEF5 PSMA2 ARHGAP17 UNC45A SLC3A2 MPRIP TLN1 ARHGAP44 RBM6 HADHB PEAK1

1.47e-059161181332203420
Pubmed

ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.

PRPS2 SPTAN1 PSMC4 PFKL TRIP12 MPRIP PRPF4 NUP133 HADHB POTEJ PCM1

1.61e-056601181132780723
Pubmed

Requirement for the Mitochondrial Pyruvate Carrier in Mammalian Development Revealed by a Hypomorphic Allelic Series.

PRPS2 PFKL MDH2 PRPS1L1 PRPS1

1.69e-0593118527215380
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

PSMA2 PSMC4 PFKL PFKM SLC3A2 KMT2C PRPF4 TLN1 ZFP91 EHMT1 HADHB ZMYM4 PCM1 PRPS1

2.34e-0511031181434189442
Pubmed

Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.

PRPS2 INTS7 SPTAN1 PSMC4 UNC45A PFKL PFKM MDH2 NCAPH SLC3A2 GDA PRPF4 TLN1 HADHB DIAPH3 PRPS1

2.42e-0514151181628515276
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

SYNE1 SPTAN1 PSMC4 UNC45A PFKL PFKM MDH2 NCAPH SLC3A2 PRPF4 TLN1 NUP133 EHMT1 HADHB PEAK1 PRPS1

2.63e-0514251181630948266
Pubmed

Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4.

SYNE1 NEK4 MAD1L1 LINC02694 CCS

2.64e-05102118521926972
Pubmed

The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.

SPTAN1 UNC45A NCAPH SLC3A2 TLN1 DIAPH3 PCM1

2.84e-05256118733397691
Pubmed

Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.

DCTN2 UNC45A TRIP12 SLC3A2 MPRIP PRPF4 PHF3 ZFP91 NUP133 EHMT1 HADHB ZMYM4

3.25e-058471181235850772
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

MON2 PSMC4 ARHGAP17 E2F3 MPRIP RBM6 DIAPH3 POTEJ ZMYM4 PCM1

3.36e-055881181038580884
Pubmed

N-acetylaspartylglutamate synthetase II synthesizes N-acetylaspartylglutamylglutamate.

RIMKLA RIMKLB

3.42e-053118221454531
Pubmed

Role of emerging vitamin K‑dependent proteins: Growth arrest‑specific protein 6, Gla‑rich protein and periostin (Review).

GAS6 POSTN

3.42e-053118233448308
Pubmed

Functional expression of human mutant phosphofructokinase in yeast: genetic defects in French Canadian and Swiss patients with phosphofructokinase deficiency.

PFKL PFKM

3.42e-05311827825568
Pubmed

Partial reconstitution of mammalian phosphoribosylpyrophosphate synthetase in Escherichia coli cells. Coexpression of catalytic subunits with the 39-kDa associated protein leads to formation of soluble multimeric complexes of various compositions.

PRPS2 PRPS1

3.42e-05311829366267
Pubmed

Isozymes of human phosphofructokinase: identification and subunit structural characterization of a new system.

PFKL PFKM

3.42e-05311826444721
Pubmed

NAAG synthetase deficiency has only low influence on pathogenesis in a Canavan disease mouse model.

RIMKLA RIMKLB

3.42e-053118238011891
Pubmed

Genomic organization, 5'flanking region and tissue-specific expression of mouse phosphofructokinase C gene.

PFKL PFKM

3.42e-053118211137296
Pubmed

The copper chaperone CCS facilitates copper binding to MEK1/2 to promote kinase activation.

MAP2K2 CCS

3.42e-053118234715128
Pubmed

Molecular mechanism of c-Myc and PRPS1/2 against thiopurine resistance in Burkitt's lymphoma.

PRPS2 PRPS1

3.42e-053118232391636
Pubmed

Alleles from chromosomes 1 and 3 of NOD mice combine to influence Sjögren's syndrome-like autoimmune exocrinopathy.

CASP8 CTLA4

3.42e-053118210955330
Pubmed

Cloning of cDNAs for human phosphoribosylpyrophosphate synthetases 1 and 2 and X chromosome localization of PRPS1 and PRPS2 genes.

PRPS2 PRPS1

3.42e-05311821962753
Pubmed

Phosphofructokinase isozyme expression during myoblast differentiation.

PFKL PFKM

3.42e-05311822521854
Pubmed

Biochemical and transcript level differences between the three human phosphofructokinases show optimisation of each isoform for specific metabolic niches.

PFKL PFKM

3.42e-053118233141153
Pubmed

Expression of phosphoribosyl pyrophosphate synthetase genes in U87 glioma cells with ERN1 knockdown: effect of hypoxia and endoplasmic reticulum stress.

PRPS2 PRPS1

3.42e-053118225816608
Pubmed

Phosphofructokinase (PFK) isozymes in man. I. Studies of adult human tissues.

PFKL PFKM

3.42e-0531182156693
Pubmed

Isozymes of human phosphofructokinase in blood cells and cultured cell lines: molecular and genetic evidence for a trigenic system.

PFKL PFKM

3.42e-05311826451249
Pubmed

Characterization of the enzymatic defect in late-onset muscle phosphofructokinase deficiency. New subtype of glycogen storage disease type VII.

PFKL PFKM

3.42e-05311822960695
Pubmed

Arginylation regulates purine nucleotide biosynthesis by enhancing the activity of phosphoribosyl pyrophosphate synthase.

PRPS2 PRPS1

3.42e-053118226175007
Pubmed

Variation in the lymphotoxin-alpha/tumor necrosis factor locus modifies risk of erythema nodosum in sarcoidosis.

SELE CTLA4 C5

3.55e-0519118319225544
Pubmed

Reduction of Nipbl impairs cohesin loading locally and affects transcription but not cohesion-dependent functions in a mouse model of Cornelia de Lange Syndrome.

PCDHB14 PCDH11X MAP2K2

3.55e-0519118323920377
Pubmed

Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level.

UBR2 DCTN2 PSMA2 RIMKLB PRPF4 NUP133

3.61e-05180118621139048
Pubmed

Genetics of rheumatoid arthritis contributes to biology and drug discovery.

TAGAP CASP8 FCRL3 CTLA4 C5

4.15e-05112118524390342
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

MON2 PRPS2 RMND5B SESTD1 DCTN2 PSMA2 WRN PSMC4 MPRIP NEK4 POSTN PRPF4 TESK2 ARHGAP44 NUP133

4.23e-0513211181527173435
Pubmed

Spatiotemporal Analysis of a Glycolytic Activity Gradient Linked to Mouse Embryo Mesoderm Development.

PRPS2 PFKL PFKM MDH2 PRPS1

4.51e-05114118528245920
Pubmed

Progesterone induced Warburg effect in HEK293 cells is associated with post-translational modifications and proteasomal degradation of progesterone receptor membrane component 1.

PFKL PFKM MPRIP MAP2K2

4.64e-0558118431067491
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

INTS7 SYNE1 WRN UNC45A PFKL SLC3A2 MPRIP KMT2C RFTN1 WDR11 PHF3 TLN1 ZFP91 EHMT1 RBM6 ZMYM4

4.75e-0514971181631527615
Pubmed

CHK2-BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly.

UBR2 SPTAN1 PSMC4 PFKL PFKM MDH2 TLN1 NUP133 RBM6

4.98e-05494118926831064
Pubmed

Network organization of the huntingtin proteomic interactome in mammalian brain.

SPTAN1 PSMC4 GRIK5 PFKL PFKM MDH2 SLC3A2 GDA HADHB RASAL1

5.31e-056211181022794259
Pubmed

HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.

INTS7 SYNE1 SPTAN1 UNC45A MDH2 NCAPH EHMT1 RBM6 ASTN1 HADHB ZMYM4

5.41e-057541181135906200
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

POLA2 NCAPH TRIP12 PHF3 MAD1L1 NUP133 RBM6 MAP2K2 PCM1

5.72e-05503118916964243
Pubmed

The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1.

SYNE1 PSMA2 SPTAN1 PFKL PRPS1L1 TLN1

5.96e-05197118620811636
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

SPTAN1 TUT7 WRN PSMC4 UNC45A MDH2 TRIP12 MPRIP PHF3 TLN1 ZFP91 C5 HADHB POTEJ PCM1

6.43e-0513711181536244648
Pubmed

Analysis of Hemicentin-1, hOgg1, and E-selectin single nucleotide polymorphisms in age-related macular degeneration.

SELE HMCN1

6.82e-054118217057786
Pubmed

Deletion of CTLA-4 on regulatory T cells during adulthood leads to resistance to autoimmunity.

NDOR1 CTLA4

6.82e-054118226371185
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

WRN MAGEC3 NCAPH TRIP12 SLC3A2 WDR11 EHMT1 PEAK1 PLEKHA8 PCM1 PRPS1

7.07e-057771181135844135
Pubmed

TNIP2 is a Hub Protein in the NF-κB Network with Both Protein and RNA Mediated Interactions.

DCTN2 SPTAN1 PSMC4 E2F3 NCAPH MPRIP PRPS1L1 RIMKLB CCDC34 EHMT1 HADHB PRPS1

7.31e-059221181227609421
Pubmed

Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.

PSMC4 PFKM MPRIP KMT2C PHF3 TLN1

8.04e-05208118633230847
Pubmed

Loss of connectin novex-3 leads to heart dysfunction associated with impaired cardiomyocyte proliferation and abnormal nuclear mechanics.

SYNE1 OBSCN PCM1

8.29e-0525118338877142
Pubmed

Host E3 ligase HUWE1 attenuates the proapoptotic activity of the MERS-CoV accessory protein ORF3 by promoting its ubiquitin-dependent degradation.

INTS7 DCTN2 PSMC4 UNC45A PFKM SLC3A2 NUP133 DIAPH3 MAP2K2

9.02e-05534118935032548
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

PRPS2 SPTAN1 TUT7 UNC45A PFKL NCAPH TRIP12 SLC3A2 MPRIP WDR11 PRPF4 PHF3 NUP133 HADHB

9.52e-0512571181436526897
Pubmed

Direct interaction between the PRDM3 and PRDM16 tumor suppressors and the NuRD chromatin remodeling complex.

PSMC4 PFKL NCAPH SLC3A2 WDR11 NUP133

9.64e-05215118630462309
Pubmed

Identification of Zika Virus and Dengue Virus Dependency Factors using Functional Genomics.

PRPS2 PFKM MDH2 SLC3A2 SCARB2 TLN1 HADHB PRPS1

1.01e-04422118827342126
Pubmed

IDD3 and IDD5 alleles from nod mice mediate Sjögren's syndrome-like autoimmunity.

CASP8 CTLA4

1.13e-045118212614028
Pubmed

Linkage of phosphoribosylpyrophosphate synthetases 1 and 2, Prps1 and Prps2, on the mouse X chromosome.

PRPS2 PRPS1

1.13e-04511827849396
Pubmed

Mitogen-inducible SIPA1 is mapped to the conserved syntenic groups of chromosome 19 in mouse and chromosome 11q13.3 centromeric to BCL1 in human.

SLC3A2 LTBP3

1.13e-04511829027487
Pubmed

PRP4 is a spindle assembly checkpoint protein required for MPS1, MAD1, and MAD2 localization to the kinetochores.

PRPF4 MAD1L1

1.13e-045118217998396
Pubmed

CTLA-4-/- mice display T cell-apoptosis resistance resembling that ascribed to autoimmune-prone non-obese diabetic (NOD) mice.

CASP8 CTLA4

1.13e-045118211247636
Pubmed

Characterization of the P5 subfamily of P-type transport ATPases in mice.

ATP13A2 ATP13A3

1.13e-045118215381061
Pubmed

Convallatoxin inhibits IL-1β production by suppressing zinc finger protein 91 (ZFP91)-mediated pro-IL-1β ubiquitination and caspase-8 inflammasome activity.

CASP8 ZFP91

1.13e-045118234825365
Pubmed

ZFP91 promotes cell proliferation and inhibits cell apoptosis in AML via inhibiting the proteasome-dependent degradation of RIP1.

CASP8 ZFP91

1.13e-045118235165513
Pubmed

Parkinson disease related ATP13A2 evolved early in animal evolution.

ATP13A2 ATP13A3

1.13e-045118229505581
Pubmed

Zinc finger protein 91 positively regulates the production of IL-1β in macrophages by activation of MAPKs and non-canonical caspase-8 inflammasome.

CASP8 ZFP91

1.13e-045118230182366
Pubmed

The coinhibitory receptor CTLA-4 controls B cell responses by modulating T follicular helper, T follicular regulatory, and T regulatory cells.

NDOR1 CTLA4

1.13e-045118225526313
Pubmed

Targeted disruption of the mouse Caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenatally.

CASP8 CTLA4

1.13e-04511829729047
Pubmed

The E3 ubiquitin ligase and RNA-binding protein ZNF598 orchestrates ribosome quality control of premature polyadenylated mRNAs.

DCTN2 SPTAN1 PSMC4 NCAPH SLC3A2 SCARB2 NUP133

1.15e-04320118728685749
Pubmed

Differences in gene expression between mouse and human for dynamically regulated genes in early embryo.

PRAMEF7 PRAMEF8 NLRP9

1.17e-0428118325089626
GeneFamilyParkinson disease associated genes|ATPase orphan transporters

ATP13A2 ATP13A3

1.87e-0457921213
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

PLEKHG4 ARHGEF5 OBSCN ARHGEF35

1.98e-0466794722
GeneFamilyAnkyrin repeat domain containing

ANKS4B CLIP4 EHMT1 KANK4 ANKRD36 POTEJ

6.65e-04242796403
GeneFamilyN-BAR domain containing

ARHGAP17 ARHGAP44

1.21e-03127921289
GeneFamilyRho GTPase activating proteins|BCH domain containing

TAGAP ARHGAP17 ARHGAP44

1.36e-0350793721
GeneFamilyGla domain containing

GAS6 POSTN

1.43e-03137921250
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

PLEKHG4 MPRIP CADPS PLEKHA8 RASAL1

2.08e-03206795682
GeneFamilyPRAME family

PRAMEF7 PRAMEF8

4.89e-0324792686
GeneFamilyNLR family

NLRP9 NLRC5

5.30e-0325792666
GeneFamilyC2-set domain containing|Immunoglobulin like domain containing|Scavenger receptors

CD163L1 SCARB2

6.16e-03277921253
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN

UBR2 WRN CASP8 E2F3 TRIP12 TIPARP RFTN1 PHF3 RBM6 ATP13A3 ZMYM4

8.65e-0646611811M13522
CoexpressionCAFFAREL_RESPONSE_TO_THC_8HR_3_DN

PCDHB14 POLA2 PRPS1

1.04e-05101183M14648
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

UBR2 WRN CASP8 E2F3 TRIP12 TIPARP NEK4 RFTN1 PHF3 MAD1L1 NUP133 RBM6 ATP13A3 ZMYM4

3.17e-0585611814M4500
CoexpressionGSE25087_FETAL_VS_ADULT_TCONV_UP

INTS7 PSMA2 PSMC4 TRIP12 TIPARP PRPF4 ZMYM4

3.39e-051991187M4645
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

MON2 UBR2 SYNE1 CASP8 PHF3 TENM1 NLRC5 ANKRD36 PCM1

3.19e-091991189f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

MXRA5 GRIK5 ARHGAP44 PCDH11X KANK4 CACNA2D3

1.00e-0518511867dcdc009c5681ee05dd18968f7e85c3403fe34af
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1|Adult / Lineage, Cell type, age group and donor

RIMKLA GAS6 ARHGAP44 DIAPH3 PEAK1 CACNA2D3

1.07e-05187118677f78aec946bc6bd85c29aee9ca978ce49f853a3
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.4.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TAGAP SYNE1 CASP8 RFTN1 FCRL3 ANKRD36

1.17e-051901186d153a0bdedcd6865e6ee19575234a78b5d859ff1
ToppCellsevere-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SYNE1 CASP8 KMT2C TENM1 ANKRD36 PCM1

1.43e-05197118657ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SYNE1 SPTAN1 CADPS ARHGAP44 PCDH11X CACNA2D3

1.47e-0519811868ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCellTracheal-NucSeq-Immune_Lymphocytic-T-T_CD4|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TAGAP JAML RFTN1 NLRC5 CTLA4 LINC02694

1.56e-052001186d8459e45a8396a9ee063666a1928c649162c5727
ToppCellTracheal-NucSeq-Immune_Lymphocytic-T-T_CD4-T_reg|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TG RFTN1 FCRL3 NLRC5 CTLA4 LINC02694

1.56e-05200118668589705dbc84482b6c0a1a27dd552492c4e8c3d
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

UBR2 CASP8 TRIP12 KMT2C PHF3 PCM1

1.56e-05200118612f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Diffuse|TCGA-Stomach / Sample_Type by Project: Shred V9

SYNE1 ITGAD RFTN1 FCRL3 POTEJ

2.42e-0512911857d537680b0dfb764f7914d0475c66b678b5cb8d2
ToppCellStriatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Excitatory_Neuron.Gad1Gad2.Resp18_(Bed_nucleus_of_the_stria_terminalis_(BNST))-|Striatum / BrainAtlas - Mouse McCarroll V32

PCDHA8 ANKS4B BNC1 ATP2C2

3.22e-05681184ea33633d93a3a7f82c9abf11472fcfb55b0c4878
ToppCellStriatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Excitatory_Neuron.Gad1Gad2.Resp18_(Bed_nucleus_of_the_stria_terminalis_(BNST))--|Striatum / BrainAtlas - Mouse McCarroll V32

PCDHA8 ANKS4B BNC1 ATP2C2

3.22e-056811845058dcaf02cc893cfd16032e0034dd9fa097c0b8
ToppCellStriatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Excitatory_Neuron.Gad1Gad2.Resp18_(Bed_nucleus_of_the_stria_terminalis_(BNST))|Striatum / BrainAtlas - Mouse McCarroll V32

PCDHA8 ANKS4B BNC1 ATP2C2

3.22e-0568118441a697c4628acc8a0f5df2f463c1fdc6ee9b7942
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c02-GPR183|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

NDOR1 JAML TENM1 CTLA4 RASAL1

3.58e-0514011857b359bfbd404ab06d799048252f4985d85852048
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HMCN1 ASTN1 KLF18 HYDIN CACNA2D3

6.76e-051601185c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HMCN1 ASTN1 KLF18 HYDIN CACNA2D3

6.76e-05160118525c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellfacs-Pancreas-Exocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCDHA8 PFKM ASTN1 TBC1D21 ZMYM4

7.38e-051631185953a7db7e90a913e81002d2141fbbd5f1fdf2197
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GDA RIMKLB TENM1 DIAPH3 HYDIN

7.60e-0516411851cb5fbd7050650047ad6f2ca792118e98d58d22b
ToppCell368C-Fibroblasts-Fibroblast-J_(Lipofibroblast)-|368C / Donor, Lineage, Cell class and subclass (all cells)

RIMKLA PCDHB14 GRIK5 BNC1 DIAPH3

8.05e-0516611854d63c758d46e73311b864148c646bf081498dee7
ToppCell368C-Fibroblasts-Fibroblast-J_(Lipofibroblast)|368C / Donor, Lineage, Cell class and subclass (all cells)

RIMKLA PCDHB14 GRIK5 BNC1 DIAPH3

8.05e-0516611854160ccf9291072a6e2782f9ad141bc9a9747f3ad
ToppCell343B-Lymphocytic-CD4_T-cell-Proliferating_T_cell|343B / Donor, Lineage, Cell class and subclass (all cells)

NCAPH TG CCDC34 CTLA4 LINC02694

8.28e-051671185315cde87eed2b42a1b9b068fae94caa10ec64c70
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Diffuse-3|TCGA-Stomach / Sample_Type by Project: Shred V9

ITGAD JAML RFTN1 FCRL3 HMCN1

8.28e-051671185d2230c894ccf9dbba9196e079ae81f384d43da63
ToppCell390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_5|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

PLEKHG4 PDLIM4 POSTN HMCN1 CADPS

8.75e-051691185d2def7229fe9d6b0c70cfed349ede491c8c137a0
ToppCellBasal_cells-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

MXRA5 PCDHB14 PDLIM4 TG RIMKLB

9.00e-051701185776d4224a682b6c648041827efd69794f88906f0
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic-Monocyte-derived_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MAGEC3 ANKS4B JAML RFTN1 CTLA4

9.51e-05172118572fbfa890995e47048b47199c170cc7dcd7661f8
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MAGEC3 ANKS4B JAML RFTN1 CTLA4

9.51e-0517211852ca6f0d1181aabe0d0e3e8f2e193f08dbda42dea
ToppCellPND03-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PRPS1L1 GDA CCDC34 NUP133 DIAPH3

1.00e-04174118565147b0f8c2ccadd5685430d31081520c157536a
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-Enterocyte|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGEF5 ANKS4B MEP1B GDA PLEKHA8

1.00e-0417411852fbdb62e269acf4447b171700a615e878dde7f9f
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-enterocyte_of_epithelium_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGEF5 ANKS4B MEP1B GDA PLEKHA8

1.00e-0417411857c52b5d8f1e65e5208c952be341fa155ed0e6e76
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Calb1-Excitatory_Neuron.Sc17a7.Calb1-Lpl_(Layer_2/3)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

HJV PLEKHG4 BNC1 ATP2C2

1.05e-04921184dfe63bb979f0382163955b32909ffab1de37685a
ToppCellcellseq2-Mesenchymal-Myocytic-Myocytic_1-Pericyte|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

GAS6 RFTN1 CD163L1 DIAPH3 SLC2A11

1.09e-04177118568263456a3c93cd195b321b309ff59e156d732fe
ToppCellcellseq2-Mesenchymal-Myocytic-Myocytic_1|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

GAS6 RFTN1 CD163L1 DIAPH3 SLC2A11

1.09e-041771185e415e448c37adc102d766235e9953dec32c021f1
ToppCell368C-Myeloid-Macrophage-SPP1+_Macrophage_3|368C / Donor, Lineage, Cell class and subclass (all cells)

TUT7 WRN KMT2C WDR11 GAREM1

1.12e-041781185536a601abcc60867949ea06e9aafb6c7b799b56b
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

RIMKLA GAS6 ARHGAP44 DIAPH3 CACNA2D3

1.15e-0417911854f6ca313b78aa93557937a046c44dcf8bcc9963c
ToppCelldroplet-Tongue-nan-24m-Myeloid-nan|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TAGAP JAML RFTN1 CD163L1 CTLA4

1.15e-0417911851b079d80f789473701c781f3431ad306e9766797
ToppCelldroplet-Heart-4Chambers-18m-Mesenchymal-cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HJV OBSCN PFKM TG CACNA2D3

1.21e-04181118509a574a3257e25c8b05a2ab20623a6b07331411a
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

WRN RFTN1 TENM1 CTLA4 PRPS1

1.21e-041811185986c036e656f24fe374807e2711cec9e3c83c892
ToppCelldroplet-Heart-4Chambers-18m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HJV OBSCN PFKM TG CACNA2D3

1.21e-041811185ac4142aa93706b7067f63d2d38e2456859e60768
ToppCellASK454-Epithelial|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

SPTAN1 GAS6 LTBP3 DIAPH3 HYDIN

1.24e-041821185ab15316cff989b61ff397a866d7ca8b49c13e981
ToppCellCTRL-Myeloid-cDC|Myeloid / Disease state, Lineage and Cell class

GAS6 RFTN1 CTLA4 RASAL1 CACNA2D3

1.24e-041821185ee137574b8f0e684a4a7cb26226877c471cae433
ToppCell356C-Lymphocytic-CD4_T-cell-Treg_cell_2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

SESTD1 NCAPH CTLA4 HADHB LINC02694

1.27e-041831185f142b320023eef00b48d4820c46214c9794d37e7
ToppCell10x5'v1-week_17-19-Lymphocytic_T-T_NK-Treg|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

CLIP4 ARHGEF35 FCRL3 TENM1 CTLA4

1.27e-0418311855fb933acfe6bc555c90dba71e75d4be658763945
ToppCell343B-Lymphocytic-CD4_T-cell-Treg_cell_4|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

E2F3 NUP133 CNDP2 CTLA4 LINC02694

1.27e-0418311853cbe0175d05fd39bc430de1ef471ff2c5b56460e
ToppCellLPS_only-Epithelial_alveolar-AT_2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGAP44 KANK4 C5 CACNA2D3 GAREM1

1.27e-041831185e972432dd4d1bd31bb0982f4df3061e5e152658f
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OBSCN HMCN1 PCDH11X TENM1 HYDIN

1.30e-0418411852cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OBSCN HMCN1 PCDH11X TENM1 HYDIN

1.30e-041841185ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c12-FOXP3|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SPTAN1 ARHGEF35 FCRL3 CTLA4 LINC02694

1.30e-04184118508bff25390e3484b75c860738396a405141b69fd
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OBSCN HMCN1 PCDH11X TENM1 HYDIN

1.30e-0418411852b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGAP44 KANK4 C5 CACNA2D3 GAREM1

1.30e-041841185ab2f06906fc7a9931dfa0864ef506832b07fb93e
ToppCell356C-Lymphocytic-CD4_T-cell-Treg_cell_2|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

SESTD1 NCAPH CTLA4 HADHB LINC02694

1.34e-041851185e06a784a297f357f3f8e761c24fa70722048ab42
ToppCellLPS_only-Epithelial_alveolar-AT_1-AT1-AT2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGAP44 KANK4 C5 CACNA2D3 GAREM1

1.34e-04185118568f428e169cfb77de970bdfdeea9b9f16f68d2ba
ToppCellLPS_only-Epithelial_alveolar|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGAP44 KANK4 C5 CACNA2D3 GAREM1

1.37e-041861185e0a2ea4b46af742bc7c9b2072bb85e27d5c92712
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SYNE1 TENM1 DIAPH3 HYDIN CACNA2D3

1.37e-041861185f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

MXRA5 GRIK5 PCDH11X KANK4 CACNA2D3

1.41e-0418711855258674d0346e5c51a4b965efcdc1790c970845d
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RIMKLB TENM1 DIAPH3 HYDIN CACNA2D3

1.41e-041871185c31130fc2f9f882944b2ba366a034a03f051c4b9
ToppCellPCW_07-8.5-Hematologic_Myeloid-Hem_Myeloid_dendritic-im_migrating_dendritic_(5)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

TAGAP ITGAD JAML CD163L1 CTLA4

1.44e-0418811858fc15c8b78fdd1a578e34325011bc5a87a8aab31
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGAP44 KANK4 C5 CACNA2D3 GAREM1

1.44e-0418811854bdf8d49af0e9da349b16e3f012e1b0eec04cc4f
ToppCell3'-GW_trimst-2-SmallIntestine-Hematopoietic-B_cells|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TAGAP FCRL3 MAD1L1 NLRC5 RASAL1

1.44e-0418811857447051dcdb949adc6af5814188674a489adf71f
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SESTD1 PDLIM4 RIMKLB DIAPH3 CACNA2D3

1.48e-0418911858c8ca3b30d9be6c854615459a7bfba82b427c8bc
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SESTD1 PDLIM4 RIMKLB DIAPH3 CACNA2D3

1.48e-0418911855d902a4660a27548764bf04c6de152b565da835c
ToppCellPND10|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SPTAN1 GAS6 MPRIP HMCN1 TLN1

1.52e-041901185d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SESTD1 DIAPH3 RASAL1 CACNA2D3 GAREM1

1.55e-0419111859032aa974aa1b7b1095b8d1b58dcb087358a5001
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SESTD1 DIAPH3 RASAL1 CACNA2D3 GAREM1

1.55e-0419111855717809a1476c20f65bce722c5a57cff92ee0d7a
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c09-GZMK-FOS_l|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SYNE1 SPTAN1 CASP8 TENM1 CTLA4

1.55e-0419111854a29b7d5cd10e9077699d3aa76e3db6c4d5a0cf6
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD4+_T-Treg|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SPTAN1 CASP8 MAD1L1 CTLA4 LINC02694

1.59e-0419211857a90ec9fc8f29216c4828e0cf5d040906456e53b
ToppCellCOVID-19_Severe-Lymphoid_T/NK-Treg|COVID-19_Severe / Disease group, lineage and cell class

SPTAN1 CASP8 MAD1L1 CTLA4 LINC02694

1.59e-0419211853fb4c148dadcf5e79094e55c6bb53ec7bf9d44c8
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD4+_T-Treg|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

SPTAN1 CASP8 MAD1L1 CTLA4 LINC02694

1.59e-041921185d883b91bbab71673de4858346d3ab33e5fbbf842
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SESTD1 SYNE1 DIAPH3 CACNA2D3 GAREM1

1.63e-041931185f42a0f02ed00fe1bb833ff0a0640d9131bca89bd
ToppCell5'-GW_trimst-2-LymphNode-Mesenchymal-fibroblastic|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PRPS2 IL17REL GAS6 PCDH11X ASTN1

1.63e-041931185c5bd0ed6f57459e54d2463318e8d9b1879718e63
ToppCellControl-Myeloid-cDC2|Myeloid / Disease state, Lineage and Cell class

GAS6 JAML RFTN1 CTLA4 RASAL1

1.63e-0419311854cb938c346cc32ec122d11e6b9f25db20e0f7ff6
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SYNE1 E2F3 FCRL3 TENM1 NLRC5

1.63e-041931185523e2541f9f8d22b3c5263839a57cc1ab23d4963
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SESTD1 SYNE1 DIAPH3 CACNA2D3 GAREM1

1.63e-04193118542df7ed37d11fb542b4d1d714b6f87ae8e1396a6
ToppCellmoderate-Epithelial-FOXN4+|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

PRPS2 CCDC34 ATP2C2 ANKRD36 PCM1

1.67e-0419411855dffa578149104dda33774361e9e77b227b5f1ce
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SYNE1 DIAPH3 HYDIN CACNA2D3 GAREM1

1.67e-041941185e577d9e88390b36b5a09b97fe1026089892275a3
ToppCell390C-Epithelial_cells-Epithelial-I_(AT1)|390C / Donor, Lineage, Cell class and subclass (all cells)

UBR2 ARHGEF5 GAS6 ATP2C2 RBM6

1.67e-04194118588db9f9e80c20ff3474f1f6459dcbdc25aec0b6d
ToppCellTracheal-10x3prime_v2-Epithelial-Epi_submucosal-gland|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

RIMKLA KANK4 ELF5 DIAPH3 RASAL1

1.67e-041941185e90f6717e3421f8978d1fc1b2f30dcf69f6fcce7
ToppCell390C-Epithelial_cells-Epithelial-I_(AT1)-|390C / Donor, Lineage, Cell class and subclass (all cells)

UBR2 ARHGEF5 GAS6 ATP2C2 RBM6

1.67e-041941185a71728202493d4858342ea2756ea281cd0d99a3a
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SESTD1 TENM1 DIAPH3 CACNA2D3 GAREM1

1.71e-041951185938b31dbf1674ee6fd0123bc88391ddcaf151217
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SYNE1 CASP8 FCRL3 TENM1 NLRC5

1.71e-04195118542382653e977714bff453bece26a6cd66ea2cc1f
ToppCellCOVID_non-vent-Lymphocytic-T_cell|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

SPTAN1 OBSCN MPRIP ANKRD36 CTLA4

1.71e-0419511854bdedd924564a260841a9153604026b57487c83d
ToppCellBLOOD--(1)_Activated_T_cells| / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

NCAPH MPRIP CTLA4 DIAPH3 LINC02694

1.71e-04195118545515d5da8a8c8242eb70a1bea24fe44eca5407b
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SESTD1 TENM1 DIAPH3 CACNA2D3 GAREM1

1.71e-041951185d39e9e6544f49e677ebe528c6fe60b99a3630e30
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SESTD1 RIMKLA GAS6 ARHGAP44 DIAPH3

1.75e-041961185eb68f7954e7c2f86d05e740e95b6e74805a6053f
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SYNE1 E2F3 FCRL3 TLN1 TENM1

1.75e-04196118517f17edadafdad9f24e88d708d7e1c765503131c
ToppCellCOVID_non-vent-Lymphocytic|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

SYNE1 SPTAN1 MPRIP FCRL3 ANKRD36

1.79e-041971185c672915f8c8c1e948d251f6eaf9f84a5600c1193
ToppCellmild-low-quality_cells|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SYNE1 CASP8 TENM1 NLRC5 ANKRD36

1.79e-041971185e4331969bd911d1ebb5453f40a7057297b5389b4
ToppCellmild-Treg|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SPTAN1 CASP8 FCRL3 MAD1L1 CTLA4

1.79e-04197118539800e6e83f2d333b753d121c7aeb2912b91faa2
ToppCell5'-GW_trimst-2-LymphNode-Mesenchymal|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PRPS2 IL17REL GAS6 PCDH11X ASTN1

1.79e-0419711855fbbc570a4e77c703f569a4f85ce2d8af67d6297
ToppCellURO-Myeloid-cDC2|URO / Disease, Lineage and Cell Type

PSMA2 GAS6 PSMC4 JAML CACNA2D3

1.79e-0419711857fee14356d7fba68a0515c8b9284568d14124b0a
ToppCellParenchymal-10x3prime_v2-Immune_Lymphocytic-T-T_CD4|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

TAGAP CASP8 JAML CTLA4 LINC02694

1.84e-041981185f486747f2c96b403bdeee0dfe0cc2679ffeefa33
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-AC-like-AC-like_Prolif-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NCAPH POSTN NLRP9 CCDC34 DIAPH3

1.84e-0419811851fa213e79d828bff6465bde116536dd1b80d94e0
ToppCellsystemic_lupus_erythematosus-flare|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SYNE1 PSMA2 PHF3 ANKRD36 PCM1

1.84e-0419811854c93ee921d56132d80832d8e94563f32ccf13bbc
ToppCell343B-Myeloid-Dendritic-cDC_proliferating_1|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

POLA2 NCAPH CCDC34 DIAPH3 CACNA2D3

1.84e-041981185281fc2536cdc4c717b30de156e563c0e4baba99d
ToppCellBronchial-NucSeq-Immune_Lymphocytic-T-T_CD4-T_reg|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CASP8 FCRL3 NLRC5 CTLA4 LINC02694

1.84e-0419811857608f67959e1cda7b10e57fd3af2f96216ebe7e9
ToppCellTracheal-NucSeq-Immune_Lymphocytic-T-T_CD4-CD4|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TAGAP JAML NLRC5 CTLA4 LINC02694

1.88e-041991185bc93e5c36ab60b66fb633c954b05d4dc09a7f152
ToppCellTracheal-NucSeq-Immune_Lymphocytic-T-T_CD8-CD8_GZMK+|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TAGAP JAML RFTN1 FCRL3 NLRC5

1.88e-04199118509e0b45529fa9d5fc86da1747b3fb3a238a09aa6
ToppCellParenchymal-10x3prime_v2-Immune_Lymphocytic-T-T_CD4-CD4_TRM/EMRA|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

TAGAP CASP8 JAML NUTM1 LINC02694

1.88e-0419911855a29db2610ba06a2248325a16cad755d20debf2c
ToppCellTracheal-NucSeq-Immune_Lymphocytic-T-T_CD4-CD4_naive/CM|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TAGAP JAML RFTN1 NLRC5 CTLA4

1.88e-0419911856150b272313d3fbf5ddcb3a8d51862d368220fe2
ToppCellhealthy_donor-Lymphocytic|healthy_donor / Disease condition, Lineage, Cell class and subclass

SYNE1 SPTAN1 FCRL3 NLRC5 ANKRD36

1.88e-0419911852841e16d54acd344ba454f024e285c28abc37319
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SYNE1 ATP2C2 ASTN1 ANKRD36 HYDIN

1.88e-04199118519a97e27a4758e794ce7246d295e112b47931a48
DrugAC1L1AO2

PRPS2 PFKL PFKM PRPS1L1 PRPS1

2.67e-08181175CID000001073
DrugLaevuflex

PRPS2 PFKL PFKM MDH2 PRPS1L1 GDA SCARB2 EHMT1 HADHB SLC2A11 PRPS1

1.64e-0727211711CID000003426
Drug2,5-anhydro-D-mannitol

PRPS2 PFKL PFKM PRPS1L1 PRPS1

5.02e-07311175CID000001494
DrugHPMPApp

PRPS2 POLA2 PRPS1L1 PRPS1

6.37e-07141174CID000506018
DrugMgCl2

PRPS2 PLEKHG4 PSMA2 SPTAN1 PSMC4 PFKM MDH2 POLA2 PRPS1L1 ATP2C2 PRPS1

2.19e-0635411711CID000024584
DrugPMEApp

PRPS2 POLA2 PRPS1L1 PRPS1

2.42e-06191174CID000447863
Drugmethyl iodoacetate

PRPS2 PRPS1L1 PRPS1

2.62e-0661173CID006429536
DrugAPP-MP

PRPS2 PRPS1L1 PRPS1

2.62e-0661173CID003081102
Drugpyrimidine-5-nucleotide

PRPS2 PRPS1L1 PRPS1

2.62e-0661173CID000440040
DrugCompound 1-4

PRPS2 SYNE1 TIPARP PRPS1L1 PRPS1

3.04e-06441175CID005311149
Drug5-o-phosphonopentose

PRPS2 PSMC4 PFKM MDH2 PRPS1L1 PRPS1

3.07e-06781176CID000000230
Drug2,3-DPG

PRPS2 PLEKHG4 SPTAN1 PFKL PFKM PRPS1L1 PRPS1

7.00e-061371177CID000000061
Drugfructose-1,6-diphosphate sodium salt

PRPS2 PSMC4 PFKL PFKM MDH2 PRPS1L1 PRPS1

1.32e-051511177CID000000718
Drugallulose 6-phosphate

PRPS2 PSMC4 PFKL PFKM MDH2 PRPS1L1 PRPS1

2.09e-051621177CID000000603
Drugpolyribosylribitol phosphate

PRPS2 PSMC4 PFKL PFKM PRPS1L1 PRPS1

2.49e-051121176CID000002219
Drug2,3,5-tri-O-benzyl-D-arabinofuranose

PFKL PFKM

2.62e-0521172CID000255457
DrugDhga

PRPS2 PRPS1L1 PRPS1

2.81e-05121173CID000467478
DrugS)-HPMPA

PRPS2 POLA2 PRPS1L1 PRPS1

3.44e-05361174CID000072253
Drug2,6,6-tetramethylpiperidine

PRPS2 PRPS1L1 PRPS1

3.64e-05131173CID000013035
Drug2,6-diaminonebularine

PRPS2 PRPS1L1 PRPS1

3.64e-05131173CID000072200
DrugAC1Q6RZ4

PRPS2 PSMC4 PFKL PFKM PRPS1L1 PRPS1

4.22e-051231176CID000000719
Drug6-o-phosphonohexose

PRPS2 PSMC4 PFKL PFKM MDH2 PRPS1L1 PRPS1

4.88e-051851177CID000099058
DrugAC1L9I7L

PRPS2 PFKM PRPS1L1 SCARB2 PRPS1

5.47e-05791175CID000445564
Drugmonomethyl succinate

PFKM MDH2 EHMT1

5.75e-05151173CID000077487
DrugAC1L2I23

PRPS2 PRPS1L1 PRPS1

7.05e-05161173CID000047419
DrugAC1L977H

PFKL PFKM

7.83e-0531172CID000439366
Diseaseamyotrophic lateral sclerosis (implicated_via_orthology)

PSMC4 ATP13A2 ATP13A3 CCS

5.17e-06301134DOID:332 (implicated_via_orthology)
DiseaseHashimoto Disease

TG CTLA4

4.35e-0531132C0677607
DiseaseHeadache, HbA1c measurement

CASP8 PFKM MAD1L1

6.92e-05211133EFO_0004541, HP_0002315
DiseaseColorectal Carcinoma

SYNE1 PSMA2 WRN OBSCN CASP8 POSTN KMT2C PCDH11X TENM1 ZMYM4 PRPS1

8.26e-0570211311C0009402
DiseaseAutoimmune thyroiditis

TG FCRL3

8.68e-0541132C0920350
DiseaseKufor-Rakeb syndrome (implicated_via_orthology)

ATP13A2 ATP13A3

8.68e-0541132DOID:0060556 (implicated_via_orthology)
Diseaseglycogen storage disease (implicated_via_orthology)

PFKL PFKM

8.68e-0541132DOID:2747 (implicated_via_orthology)
Diseaselevel of meprin A subunit beta in blood serum

MEP1B GAREM1

8.68e-0541132OBA_2044983
Diseasejuvenile-onset Parkinson's disease (implicated_via_orthology)

ATP13A2 ATP13A3

8.68e-0541132DOID:0060893 (implicated_via_orthology)
DiseaseMalignant neoplasm of breast

SYNE1 SPTAN1 OBSCN CASP8 NLRP9 FCRL3 NUP133 TENM1 EHMT1 NLRC5 HADHB PLEKHA8 PRPS1

2.43e-04107411313C0006142
DiseaseGraves Disease

FCRL3 CTLA4

5.14e-0491132C0018213
Diseaseeconomic and social preference

GRIK5 CADPS ARHGAP44 PCM1

5.37e-04971134EFO_0004827
Diseasecorpus callosum volume measurement

ATP13A2 TG TLN1 RBM6

6.03e-041001134EFO_0010299
Diseasehereditary spastic paraplegia (implicated_via_orthology)

PSMC4 ATP13A2 ATP13A3

6.04e-04431133DOID:2476 (implicated_via_orthology)
Diseaseendometrial neoplasm

ZMYM4 CACNA2D3

7.82e-04111132EFO_0004230
Diseaseautoimmune thyroiditis (is_implicated_in)

TG CTLA4

9.36e-04121132DOID:7188 (is_implicated_in)
Diseasetriacylglycerol 58:12 measurement

E2F3 TRIP12

9.36e-04121132EFO_0010439
DiseaseSubstance abuse problem

SYNE1 WDR11 PRPF4 ASTN1

1.05e-031161134C0740858
Diseasecorpus callosum posterior volume measurement

ATP13A2 RBM6 GAREM1

1.05e-03521133EFO_0010298
Diseaseneuronal ceroid lipofuscinosis (implicated_via_orthology)

ATP13A2 ATP13A3

1.28e-03141132DOID:14503 (implicated_via_orthology)
DiseaseOsteoporosis, Age-Related

PSMA2 PDLIM4 TLN1

1.67e-03611133C0001787
DiseasePost-Traumatic Osteoporosis

PSMA2 PDLIM4 TLN1

1.67e-03611133C0751406
DiseaseOsteoporosis, Senile

PSMA2 PDLIM4 TLN1

1.67e-03611133C0029459
Diseasesevere acute respiratory syndrome, COVID-19

MXRA5 WRN TG CADPS PCDH11X LTBP3 CACNA2D3

1.70e-034471137EFO_0000694, MONDO_0100096
DiseaseOsteoporosis

PSMA2 PDLIM4 TLN1

1.84e-03631133C0029456
Diseasesquamous cell carcinoma (is_implicated_in)

KMT2C CTLA4

2.14e-03181132DOID:1749 (is_implicated_in)
Diseasebipolar I disorder

SYNE1 MAD1L1 LINC02694 TBC1D21

2.15e-031411134EFO_0009963
Diseaseevent free survival time, urinary bladder cancer

ARHGAP17 MAD1L1

2.38e-03191132EFO_0000482, MONDO_0001187
DiseaseBipolar Disorder

SYNE1 CASP8 GRIK5 PFKL NEK4 CTLA4 LINC02694

2.45e-034771137C0005586
Diseaseurinary microalbumin measurement

MON2 GDA

2.64e-03201132EFO_0010967
Diseasedisease of metabolism (implicated_via_orthology)

PFKL PFKM

2.91e-03211132DOID:0014667 (implicated_via_orthology)
DiseaseNon-Small Cell Lung Carcinoma

MXRA5 CASP8 E2F3 MAP2K2

3.10e-031561134C0007131
DiseaseGraves disease

TG FCRL3 CTLA4

3.76e-03811133EFO_0004237
DiseaseAlcoholic Intoxication, Chronic

TIPARP PHF3 TESK2 ASTN1 LINC02694

3.77e-032681135C0001973
Diseasestomach carcinoma (is_marker_for)

SLC3A2 KMT2C

3.80e-03241132DOID:5517 (is_marker_for)

Protein segments in the cluster

PeptideGeneStartEntry
INGTCIVNESMLTGE

ATP13A3

311

Q9H7F0
CADGLLGEEQMIEQV

ARHGEF5

251

Q12774
LMEDSDGNCEGSSLV

BNC1

886

Q01954
CADGLLGEEQMIEQV

ARHGEF35

251

A5YM69
DDEATLNGMGLVIAQ

ARMH3

236

Q5T2E6
LDAACGIDKTENGNM

ANKRD36

441

A6QL64
GNESLLDNCQMTVLG

CD163L1

971

Q9NR16
GLQGACLMETVELLQ

DCTN2

251

Q13561
GDETGVMDNLLEALQ

DIAPH3

1056

Q9NSV4
GCNVNDRDGLTDMTL

CLIP4

96

Q8N3C7
QCDVIVAGGVELMSD

HADHB

156

P55084
SMTQEEFVEAAGLCG

ELF5

101

Q9UKW6
LCNGKLQAMSGEEVD

ATP2C2

616

O75185
TLDSLQGCNEKSGMD

ASTN1

271

O14525
RDTGQCMASLQEISG

NWD2

1261

Q9ULI1
CDFGVSGQLIDSMAN

MAP2K2

211

P36507
VQGEICLSVQMLEDG

RASAL1

116

O95294
LEDQSSKAGDMGNCV

RFTN1

481

Q14699
MAFSAEQDLQLCVGG

HJV

306

Q6ZVN8
IQVSNILGMDFCGID

RIMKLA

246

Q8IXN7
TTIAMTLGNDLQRCG

INTS7

651

Q9NVH2
QENGIEICMDFLQGT

TIPARP

236

Q7Z3E1
CTMEVEGGEKLQTDQ

CADPS

421

Q9ULU8
SLITIEDNGCQMSDA

NUP133

371

Q8WUM0
DLDSGANGQVTCSLM

PCDHA8

376

Q9Y5H6
EEESGMSDQLCGIAA

KIAA0100

1551

Q14667
GTINMNQCTDVVDGE

MPRIP

96

Q6WCQ1
GVCLTESGMTQLQSL

KMT2C

1176

Q8NEZ4
EMEAQLSQALEELGG

MAD1L1

451

Q9Y6D9
LDLTCEGSLSDEQGM

MAGEC3

256

Q8TD91
GLEACAMSLDTQETQ

IL17REL

41

Q6ZVW7
SLVDAMNGKEGVVEC

MDH2

261

P40926
GEICEMQTEELAGNS

PCM1

1996

Q15154
LVGSIDNDFCGTDMT

PFKL

161

P17858
LVGSIDNDFCGTDMT

PFKM

161

P08237
TMIVADGQSICGELS

PEAK1

76

Q9H792
ELGGICSISQVEEEM

NEK4

396

P51957
ITLCTGDELTLMGQA

GAREM1

146

Q9H706
DCEEGFELMGAQSLQ

SELE

271

P16581
LCSDEDLQSIQMQLG

ANKS4B

376

Q8N8V4
ELSTCENGSLNMEIN

PLEKHA8

216

Q96JA3
SMIEGELGELETECQ

MON2

501

Q7Z3U7
GNITLMEKCDVTDLG

PCDH11X

731

Q9BZA7
NTKVMLISDIDGDGC

ITFG2

126

Q969R8
EALMSIFQEEGGLCS

NDOR1

561

Q9UHB4
DLSGNQLEDEGCRLM

NLRC5

876

Q86WI3
GMTKAENGTCIDIDE

HMCN1

5261

Q96RW7
TCQGNLLIMGTEDAS

NUTM1

861

Q86Y26
QDLTQDGLMDLAVGA

ITGAD

591

Q13349
CELQIRGLAMADTGE

OBSCN

3591

Q5VST9
LDQDSGDNGRMICSI

PCDHB14

371

Q9Y5E9
GECMVNESSLTGESI

ATP13A2

336

Q9NQ11
GNTELTGQEELMEIS

FAM126A

331

Q9BYI3
ESLQTCEQNEMLSIG

HYDIN

1311

Q4G0P3
SLVVLGSAMELCGND

SLC2A11

276

Q9BYW1
GMLAQCQGLSKEVTE

E2F3

251

O00716
RGMELQGCASTQVES

CCDC34

111

Q96HJ3
GQGSICSQAIMLITD

CACNA2D3

356

Q8IZS8
GGLKLSQDMDTCEDI

GAS6

266

Q14393
DCGQMQEELDLTISA

C5

1531

P01031
MASDSGNQGTLCTLE

CCS

1

O14618
EMIETGSDCVTQAGL

SLC3A2

66

P08195
FSNGEELCGVMTISD

CASP8

196

Q14790
RDSCQQGSNMTLIGE

LTBP3

81

Q9NS15
GGQLIEGENMVLICS

FCRL3

296

Q96P31
EGENMVLICSVAQGS

FCRL3

301

Q96P31
LSCSETLMGELGNIA

GDA

216

Q9Y2T3
ESCDKGIEVNLLGSM

KANK4

426

Q5T7N3
EQVMTSTGNQALCGE

KLF18

656

A0A0U1RQI7
MGNELTFLDDSICTG

CTLA4

91

P16410
MAAILDDQTVCGRGE

GRIK5

26

Q16478
QTLDLEDCGIMDSQL

PRAMEF8

351

Q5VWM4
MLVQAGANIDTCSED

EHMT1

791

Q9H9B1
SFELENVCGMIQSSG

MEP1B

266

Q16820
LSTCENGSLNMEING

PLEKHA8P1

101

O95397
SLLEDAIGCMEANQG

RBM6

506

P78332
SGADINSICQESGML

PSMC4

371

P43686
VLQESMGGDDILLAC

TBC1D21

286

Q8IYX1
NNMETLIECQSEGDI

TAGAP

16

Q8N103
SLQDMSCQLLVNAEG

SYNE1

8611

Q8NF91
MADLGLTECCGNSNL

PLEKHG4

976

Q58EX7
GKMLETCGDAENQLA

ARHGAP17

91

Q68EM7
MGLDISSDGQLIATC

PRPF4

496

O43172
MGDILCNDGSLLLQD

JAML

91

Q86YT9
GDLIQAINGESTELM

PDLIM4

46

P50479
DDTAVLVIDNGSGMC

POTEJ

666

P0CG39
ITDKCNMINGTDGDS

SCARB2

241

Q14108
MLCGDNLDNDGDGLT

TENM1

801

Q9UKZ4
CSGNMGLLQQLEADI

WRN

646

Q14191
QNEEGMVGELIAFCT

POLA2

36

Q14181
VCRGLEESLGMVAQA

OVCA2

91

Q8WZ82
VQSGCGEINDSLMEL

PRPS1L1

56

P21108
QCLMEGSAILGDDTL

ARHGAP44

76

Q17R89
SQQLDGLLGMLCVDV

SESTD1

391

Q86VW0
SCQEEMISLGDGDIR

NCAPH

401

Q15003
VNVRFCLEGMEESGS

CNDP2

156

Q96KP4
MELQGAQEDLGISLS

LINC02694

1

Q8NAA6
NVCEMNGIAETSLLE

NLRP9

186

Q7RTR0
QTLDLEDCGIMDSQL

PRAMEF7

351

Q5VXH5
REETLQTMVLGCQAG

nan

491

Q6ZTK2
DMLTAAQGGICLALD

ERVFRD-1

421

P60508
QGMLSVAEELCQEST

RMND5B

131

Q96G75
GCLDSVMENSKVLGE

TLN1

1391

Q9Y490
GSCMVEESGTLESQL

SPTAN1

2231

Q13813
IQSGCGEINDNLMEL

PRPS2

56

P11908
CVGLSLSQAQQMGEE

PHF3

746

Q92576
GQMTEDNIEVGICNE

PSMA2

201

P25787
QVSNILGMDVCGIDL

RIMKLB

251

Q9ULI2
VQSGCGEINDNLMEL

PRPS1

56

P60891
NSTSGECLLLEAEGM

ZFP91

501

Q96JP5
NMLAEIFCQTGGVED

ZBED1

546

O96006
SLDNMIGQSAIAGEE

WDR11

426

Q9BZH6
LNTLQCSESIMGGAV

POSTN

306

Q15063
EAMDCSILQEENGFG

TESK2

511

Q96S53
VCMTINGLETAEGLD

TUT7

1061

Q5VYS8
TMNGCSVEDLGLDFT

TRIP12

1781

Q14669
ILLTSCTEENGMDQE

UBR2

1456

Q8IWV8
TLNSLGIQMCSEENG

TG

2026

P01266
QMTGLQCSSALGALD

nan

71

Q499Y3
CDAGNRALELSGVME

UNC45A

426

Q9H3U1
VFDEIVENCGGIMDT

ZMYM4

21

Q5VZL5
CQGSTMELLQDVSDV

TRIM6

241

Q9C030
SDSVQLVCMARNEGG

MXRA5

2511

Q9NR99