Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionglutathione hydrolase activity

GGTLC2 GGT3P GGTLC3 GGTLC1

1.98e-0791284GO:0036374
GeneOntologyMolecularFunctionomega peptidase activity

GGTLC2 GGT3P GGTLC3 GGTLC1

2.76e-06161284GO:0008242
GeneOntologyMolecularFunctionpeptidyltransferase activity

GGTLC2 GGT3P GGTLC1

5.07e-0661283GO:0000048
GeneOntologyMolecularFunctionleukotriene-C(4) hydrolase

GGTLC2 GGT3P GGTLC1

5.07e-0661283GO:0002951
GeneOntologyMolecularFunctionthreonine-type peptidase activity

GGTLC2 GGT3P GGTLC3 GGTLC1

7.21e-06201284GO:0070003
GeneOntologyMolecularFunctionleukotriene C4 gamma-glutamyl transferase activity

GGTLC2 GGT3P GGTLC1

1.41e-0581283GO:0103068
GeneOntologyMolecularFunctionoxalate transmembrane transporter activity

SLC26A3 SLC26A5 SLC26A9

2.99e-05101283GO:0019531
GeneOntologyMolecularFunctionP-type divalent copper transporter activity

ATP7A ATP7B

4.08e-0521282GO:0043682
GeneOntologyMolecularFunctionP-type monovalent copper transporter activity

ATP7A ATP7B

4.08e-0521282GO:0140581
GeneOntologyMolecularFunctionchloride:bicarbonate antiporter activity

SLC26A3 SLC26A5 SLC26A9

7.02e-05131283GO:0140900
GeneOntologyMolecularFunctionbicarbonate:monoatomic anion antiporter activity

SLC26A3 SLC26A5 SLC26A9

7.02e-05131283GO:0140829
GeneOntologyMolecularFunctionsulfate transmembrane transporter activity

SLC26A3 SLC26A5 SLC26A9

1.36e-04161283GO:0015116
GeneOntologyMolecularFunctionintramembrane lipid transporter activity

ANO4 ABCA12 ANO1 ATP8B1

3.19e-04511284GO:0140303
GeneOntologyMolecularFunctionGTPase activator activity

DOCK3 TBC1D9 ARFGAP2 NF1 AGAP7P AGAP4 AGAP6 ARAP2

4.42e-042791288GO:0005096
GeneOntologyMolecularFunctiondicarboxylic acid transmembrane transporter activity

SLC26A3 SLC26A5 SLC26A9

1.01e-03311283GO:0005310
GeneOntologyMolecularFunctioncopper ion transmembrane transporter activity

ATP7A ATP7B

1.11e-0381282GO:0005375
GeneOntologyMolecularFunctionbicarbonate transmembrane transporter activity

SLC26A3 SLC26A5 SLC26A9

1.11e-03321283GO:0015106
GeneOntologyMolecularFunctionsolute:inorganic anion antiporter activity

SLC26A3 SLC26A5 SLC26A9

1.11e-03321283GO:0005452
GeneOntologyMolecularFunctionchloride transmembrane transporter activity

ANO4 SLC26A3 SLC26A5 ANO1 SLC26A9

1.27e-031251285GO:0015108
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

SMARCA5 ATP7A ATP7B ABCA12 ABCA13 NTPCR ATP8B1 CLPX GNA13 AGAP7P AGAP4 AGAP6 DYNC1H1

1.43e-0377512813GO:0017111
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

DOCK3 TBC1D9 ARFGAP2 NF1 GNA13 SBF2 AGAP7P AGAP4 AGAP6 ARAP2

1.60e-0350712810GO:0060589
GeneOntologyMolecularFunctionGTPase regulator activity

DOCK3 TBC1D9 ARFGAP2 NF1 GNA13 SBF2 AGAP7P AGAP4 AGAP6 ARAP2

1.60e-0350712810GO:0030695
GeneOntologyMolecularFunctionlipid transporter activity

ANO4 ABCA12 ABCA13 ANO1 ATP8B1 SLC2A1

1.67e-031961286GO:0005319
GeneOntologyMolecularFunctionATP-dependent activity

SMARCA5 ATP7A ATP7B MYO5A ABCA12 ABCA13 NTPCR ATP8B1 CLPX RAD54B DYNC1H1

2.01e-0361412811GO:0140657
GeneOntologyMolecularFunctionsecondary active sulfate transmembrane transporter activity

SLC26A3 SLC26A5

2.16e-03111282GO:0008271
GeneOntologyMolecularFunctionATP hydrolysis activity

SMARCA5 ATP7A ATP7B ABCA12 ABCA13 NTPCR ATP8B1 CLPX DYNC1H1

2.17e-034411289GO:0016887
GeneOntologyMolecularFunctionG-protein alpha-subunit binding

DRD5 ADGRV1 PKD1L2

2.63e-03431283GO:0001965
GeneOntologyMolecularFunctionphospholipid binding

HIP1R ATP8B1 NF1 PIK3C2A SBF2 AGAP7P EPDR1 AGAP4 AGAP6 ARAP2

2.81e-0354812810GO:0005543
GeneOntologyMolecularFunctiontransition metal ion transmembrane transporter activity

ATP7A ATP7B SLC39A9

2.81e-03441283GO:0046915
GeneOntologyMolecularFunctionpyrophosphatase activity

SMARCA5 ATP7A ATP7B ABCA12 ABCA13 NTPCR ATP8B1 CLPX GNA13 AGAP7P AGAP4 AGAP6 DYNC1H1

2.86e-0383912813GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

SMARCA5 ATP7A ATP7B ABCA12 ABCA13 NTPCR ATP8B1 CLPX GNA13 AGAP7P AGAP4 AGAP6 DYNC1H1

2.89e-0384012813GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

SMARCA5 ATP7A ATP7B ABCA12 ABCA13 NTPCR ATP8B1 CLPX GNA13 AGAP7P AGAP4 AGAP6 DYNC1H1

2.89e-0384012813GO:0016818
GeneOntologyMolecularFunctionmonoatomic anion transmembrane transporter activity

ANO4 SLC26A3 SLC26A5 ANO1 SLC26A9

2.91e-031511285GO:0008509
GeneOntologyMolecularFunctioncalcium ion binding

FAT4 COMP MYO5A MATN2 ADGRV1 PKD1L2 TBC1D9 STAB1 MAN1A2 HMCN1 PCDH11X EPDR1

3.17e-0374912812GO:0005509
GeneOntologyBiologicalProcessleukotriene D4 biosynthetic process

GGTLC2 GGT3P GGTLC3 GGTLC1

2.89e-07101284GO:1901750
GeneOntologyBiologicalProcessglutathione catabolic process

GGTLC2 GGT3P GGTLC3 GGTLC1

4.51e-07111284GO:0006751
GeneOntologyBiologicalProcessleukotriene D4 metabolic process

GGTLC2 GGT3P GGTLC3 GGTLC1

6.74e-07121284GO:1901748
GeneOntologyBiologicalProcessleukotriene biosynthetic process

GGTLC2 GGT3P GGTLC3 GGTLC1

9.49e-06221284GO:0019370
GeneOntologyBiologicalProcesscysteine biosynthetic process

GGTLC2 GGT3P GGTLC1

1.28e-0581283GO:0019344
GeneOntologyBiologicalProcesspeptide modification

GGTLC2 GGT3P GGTLC1

2.71e-05101283GO:0031179
GeneOntologyBiologicalProcessoxalate transport

SLC26A3 SLC26A5 SLC26A9

4.93e-05121283GO:0019532
GeneOntologyBiologicalProcessmodified amino acid catabolic process

GGTLC2 GGT3P GGTLC3 GGTLC1

7.97e-05371284GO:0042219
GeneOntologyBiologicalProcessbicarbonate transport

SLC26A3 CYB5RL SLC26A5 SLC26A9

8.87e-05381284GO:0015701
GeneOntologyBiologicalProcesscopper ion export

ATP7A ATP7B

1.14e-0431282GO:0060003
GeneOntologyBiologicalProcessnegative regulation of catalytic activity

DRD5 ACACB CD109 ADGRV1 WNK1 BIRC6 LEPR NR2F2 PLA2R1 SERPINA4 NF1 PTPRJ PZP

1.19e-0461512813GO:0043086
GeneOntologyBiologicalProcessleukotriene metabolic process

GGTLC2 GGT3P GGTLC3 GGTLC1

1.20e-04411284GO:0006691
GeneOntologyBiologicalProcesssulfate transmembrane transport

SLC26A3 SLC26A5 SLC26A9

1.23e-04161283GO:1902358
GeneOntologyBiologicalProcesscysteine metabolic process

GGTLC2 GGT3P GGTLC1

1.23e-04161283GO:0006534
GeneOntologyBiologicalProcesschloride transport

ANO4 SLC26A3 SLC26A5 ANO1 SLC26A9 ATP8B1

1.48e-041281286GO:0006821
GeneOntologyBiologicalProcessproteinogenic amino acid metabolic process

ATP7A GGTLC2 GFPT1 GGT3P PRODH2 GGTLC1 HDC

1.58e-041851287GO:0170039
GeneOntologyBiologicalProcesshomophilic cell adhesion via plasma membrane adhesion molecules

FAT4 NRCAM KIRREL3 HMCN1 PKD1 PCDH11X AMIGO2

1.69e-041871287GO:0007156
GeneOntologyBiologicalProcesspositive regulation of cell size

ATP7A SLC26A5 KDM1A

2.10e-04191283GO:0045793
GeneOntologyBiologicalProcessglutathione biosynthetic process

GGTLC2 GGT3P GGTLC1

2.46e-04201283GO:0006750
GeneOntologyBiologicalProcesssulfur amino acid biosynthetic process

GGTLC2 GGT3P GGTLC1

2.86e-04211283GO:0000097
GeneOntologyBiologicalProcessfatty acid derivative biosynthetic process

GGTLC2 GGT3P GGTLC3 GGTLC1

3.04e-04521284GO:1901570
GeneOntologyBiologicalProcessL-amino acid metabolic process

ATP7A GGTLC2 GFPT1 GGT3P PRODH2 GGTLC1 HDC

3.23e-042081287GO:0170033
GeneOntologyBiologicalProcesssulfur compound catabolic process

GGTLC2 GGT3P GGTLC3 GGTLC1

3.27e-04531284GO:0044273
GeneOntologyBiologicalProcessnonribosomal peptide biosynthetic process

GGTLC2 GGT3P GGTLC1

3.30e-04221283GO:0019184
GeneOntologyCellularComponentcell surface

CD244 NRCAM CCR9 CD109 ANO1 SLC26A9 ADGRV1 VWDE LEPR PLA2R1 CLEC4F PTPRJ IGHG2 MRC2 PKD1 CUZD1 PKHD1 ADAM17

1.48e-04111112818GO:0009986
GeneOntologyCellularComponentbrush border membrane

SLC26A3 DRD5 ATP7A ATP8B1 GNA13

1.58e-04831285GO:0031526
GeneOntologyCellularComponentcell projection membrane

SLC26A3 DRD5 ATP7A HIP1R ATP8B1 ADGRV1 PTPRJ GNA13 PKD1 ADAM17

3.26e-0443112810GO:0031253
MousePhenopriapism

ATP7A GGTLC2 GGT3P GGTLC1

2.43e-06141014MP:0003415
MousePhenoabnormal circulating glutathione level

GGTLC2 GGT3P GGTLC1

3.62e-0651013MP:0030652
MousePhenoincreased circulating glutathione level

GGTLC2 GGT3P GGTLC1

3.62e-0651013MP:0030653
MousePhenoglutathionuria

GGTLC2 GGT3P GGTLC1

3.62e-0651013MP:0013730
MousePhenoincreased glutathione level

GGTLC2 GGT3P GGTLC1

3.62e-0651013MP:0012606
MousePhenodiluted coat color

ATP7A ATP7B MYO5A GGTLC2 GGT3P GGTLC1

6.54e-06641016MP:0000371
MousePhenoabnormal penile erection

ATP7A GGTLC2 GGT3P GGTLC1

7.27e-06181014MP:0001379
MousePhenoabnormal copulation physiology

ATP7A GGTLC2 GGT3P GGTLC1

9.15e-06191014MP:0031627
MousePhenodecreased circulating cysteine level

GGTLC2 GGT3P GGTLC1

1.25e-0571013MP:0030626
MousePhenoabsent estrous cycle

GGTLC2 LEPR NR2F2 GGT3P GGTLC1

1.55e-05441015MP:0009009
MousePhenodecreased cysteine level

GGTLC2 GGT3P GGTLC1

2.00e-0581013MP:0030623
MousePhenoepididymis hypoplasia

GGTLC2 GGT3P GGTLC1

2.00e-0581013MP:0004932
MousePhenoincreased circulating potassium level

DELE1 ATP8B1 LEPR PIK3C2A AGAP7P AGAP4 AGAP6

2.68e-051211017MP:0005627
MousePhenonervous

GGTLC2 GGT3P GGTLC1

2.98e-0591013MP:0008912
MousePhenoabnormal circulating potassium level

SLC26A3 DELE1 ATP8B1 LEPR PIK3C2A AGAP7P AGAP4 AGAP6

3.27e-051711018MP:0002668
MousePhenonuclear cataract

NRCAM GGTLC2 GGT3P GGTLC1

3.40e-05261014MP:0010254
MousePhenoabnormal circulating amino acid level

ZNF354A ITPRID2 GGTLC2 TEAD3 NDUFS1 LEPR GGT3P PRODH2 USP38 PIK3C2A GGTLC1 PKD1 GPR176

4.15e-0548110113MP:0005311
MousePhenofailure of copulatory plug deposition

GGTLC2 GGT3P GGTLC1

4.23e-05101013MP:0030983
MousePhenoseminal vesicle hypoplasia

GGTLC2 GGT3P GGTLC1

4.23e-05101013MP:0005148
MousePhenoovary hypoplasia

GGTLC2 GGT3P GGTLC1

4.23e-05101013MP:0005158
MousePhenoabnormal kidney copper level

ATP7A ATP7B

5.17e-0521012MP:0010242
MousePhenoincreased kidney copper level

ATP7A ATP7B

5.17e-0521012MP:0010243
MousePhenoincreased brain copper level

ATP7A ATP7B

5.17e-0521012MP:0011214
MousePhenoaminoaciduria

GGTLC2 GGT3P PRODH2 GGTLC1

5.31e-05291014MP:0003311
MousePhenodisproportionate dwarf

COMP GGTLC2 GGT3P GGTLC1 PKD1

5.54e-05571015MP:0002427
MousePhenoabnormal circulating cysteine level

GGTLC2 GGT3P GGTLC1

5.79e-05111013MP:0030624
MousePhenoabsent tertiary ovarian follicles

GGTLC2 GGT3P GGTLC1

5.79e-05111013MP:0011130
MousePhenoabnormal potassium level

SLC26A3 DELE1 ATP8B1 LEPR PIK3C2A AGAP7P AGAP4 AGAP6

8.59e-051961018MP:0020887
MousePhenoanovulation

GGTLC2 LEPR GGT3P GGTLC1

8.94e-05331014MP:0008869
MousePhenoabnormal potassium ion homeostasis

SLC26A3 DELE1 ATP8B1 LEPR PIK3C2A AGAP7P AGAP4 AGAP6

9.22e-051981018MP:0011978
MousePhenoabnormal cysteine level

GGTLC2 GGT3P GGTLC1

9.93e-05131013MP:0030621
MousePhenodecreased glutathione level

GGTLC2 GGT3P GGTLC1

9.93e-05131013MP:0012604
MousePhenoabnormal glutathione level

GGTLC2 GGT3P GGTLC1

9.93e-05131013MP:0012603
MousePhenodecreased liver copper level

ATP7A ATP7B

1.54e-0431012MP:0003067
MousePhenodecreased circulating copper level

ATP7A ATP7B

1.54e-0431012MP:0006349
MousePhenopostnatal growth retardation

ATP7A ATP7B MYO5A HMX3 ANO1 ATP8B1 ITPRID2 GGTLC2 NR2F2 GGT3P PIK3C2A GGTLC1 BUB1B PKD1 PKHD1 PRKDC DYNC1H1

1.78e-0488110117MP:0001732
MousePhenoabnormal copulatory plug deposition

GGTLC2 GGT3P GGTLC1

1.91e-04161013MP:0030982
MousePhenodecreased spleen red pulp amount

GGTLC2 GGT3P GGTLC1

1.91e-04161013MP:0008477
MousePhenoabnormal amino acid level

ZNF354A ITPRID2 GGTLC2 TEAD3 NDUFS1 LEPR GGT3P PRODH2 USP38 PIK3C2A GGTLC1 PKD1 GPR176

2.28e-0457010113MP:0005332
MousePhenoinduced hyperactivity

GGTLC2 GGT3P FABP7 GGTLC1

2.33e-04421014MP:0008911
MousePhenoabnormal postnatal growth

ATP7A ATP7B MYO5A HMX3 ANO1 ATP8B1 ITPRID2 GGTLC2 NR2F2 GGT3P PIK3C2A GGTLC1 BUB1B PKD1 PKHD1 PRKDC DYNC1H1

2.51e-0490710117MP:0001731
MousePhenofailure of superovulation

GGTLC2 GGT3P GGTLC1

2.76e-04181013MP:0031422
MousePhenooocyte degeneration

GGTLC2 GGT3P GGTLC1

2.76e-04181013MP:0009093
MousePhenodecreased follicle stimulating hormone level

GGTLC2 LEPR GGT3P GGTLC1

2.79e-04441014MP:0005130
MousePhenoabnormal organ of Corti supporting cell morphology

SLC26A5 ATP8B1 ADGRV1 NR2F1

2.79e-04441014MP:0004300
MousePhenoabnormal amino acid derivative level

ATP7A ITPRID2 GGTLC2 GGT3P PRODH2 GGTLC1

2.87e-041251016MP:0021145
MousePhenoincreased copper level

ATP7A ATP7B

3.07e-0441012MP:0014539
MousePhenoabnormal circulating copper level

ATP7A ATP7B

3.07e-0441012MP:0006348
MousePhenoincreased circulating growth hormone level

GGTLC2 GGT3P GGTLC1

3.26e-04191013MP:0005123
MousePhenodecreased thyroxine level

ITPRID2 GGTLC2 GGT3P GGTLC1

4.94e-04511014MP:0005471
MousePhenodecreased copper level

ATP7A ATP7B

5.10e-0451012MP:0014540
MousePhenoabnormal hair follicle infundibulum morphology

ACER1 CD109

5.10e-0451012MP:0010682
MousePhenoabnormal brain copper level

ATP7A ATP7B

5.10e-0451012MP:0011213
MousePhenosmall vertebrae

GGTLC2 GGT3P GGTLC1

5.10e-04221013MP:0004610
MousePhenoincreased growth hormone level

GGTLC2 GGT3P GGTLC1

5.84e-04231013MP:0005137
MousePhenoabnormal kidney epithelial cell primary cilium morphology

PKD1 PKHD1 B9D1

5.84e-04231013MP:0011065
MousePhenouterus hypoplasia

GGTLC2 GGT3P GGTLC1

5.84e-04231013MP:0001121
MousePhenoabnormal sexual interaction

GGTLC2 LEPR GGT3P KIRREL3 GGTLC1

5.88e-04941015MP:0002566
MousePhenoaciduria

GGTLC2 GGT3P PRODH2 GGTLC1

6.60e-04551014MP:0010028
MousePhenoabnormal copulation behavior

GGTLC2 GGT3P GGTLC1

6.64e-04241013MP:0009697
MousePhenofused cornea and lens

AGAP7P AGAP4 AGAP6

6.64e-04241013MP:0001307
MousePhenoabnormal orientation of outer hair cell stereociliary bundles

FAT4 ADGRV1 NR2F1

6.64e-04241013MP:0004491
MousePhenoabnormal bile duct physiology

ATP8B1 PKD1 PKHD1

7.50e-04251013MP:0003252
MousePhenoabnormal growth hormone level

HMX3 GGTLC2 GGT3P GGTLC1

7.56e-04571014MP:0003968
MousePhenoabnormal liver copper level

ATP7A ATP7B

7.61e-0461012MP:0003065
MousePhenobile duct inflammation

PKD1 PKHD1

7.61e-0461012MP:0003254
MousePhenoconvulsive seizures

ATP7A NRCAM MYO5A ADGRV1 SLC2A1 KDM1A

8.40e-041531016MP:0000947
MousePhenoabnormal kidney cell proliferation

FAT4 PKD1 PKHD1

8.44e-04261013MP:0011439
MousePhenocurly vibrissae

ATP7A ATP7B ADAM17

8.44e-04261013MP:0001274
MousePhenoabnormal urine amino acid level

GGTLC2 GGT3P PRODH2 GGTLC1

8.61e-04591014MP:0011468
MousePhenocataract

NRCAM GGTLC2 NDUFS1 GGT3P HMCN1 GGTLC1 BUB1B ADAM17 AGAP7P AGAP4 AGAP6

9.09e-0449710111MP:0001304
MousePhenodecreased circulating insulin-like growth factor I level

ITPRID2 GGTLC2 GGT3P GGTLC1

9.77e-04611014MP:0004701
MousePhenoabnormal kidney epithelium morphology

ANO1 PKD1 PKHD1 B9D1

9.77e-04611014MP:0004967
MousePhenoabnormal nephron morphology

FAT4 ATP7A ANO1 LEPR NF1 PIK3C2A PKD1 PKHD1 B9D1 PRKDC

1.01e-0342610110MP:0003881
MousePhenocornea opacity

SLC26A9 ATP8B1 ADAM17 AGAP7P AGAP4 AGAP6

1.03e-031591016MP:0001314
MousePhenodilated hair follicle

ACER1 CD109

1.06e-0371012MP:0010699
MousePhenobile duct hyperplasia

PKHD1 B9D1

1.06e-0371012MP:0004839
MousePhenoabsent estrus

LEPR NR2F2

1.06e-0371012MP:0009021
MousePhenoabnormal exocrine gland morphology

SLC26A3 ACER1 CD109 SLC26A9 ATP8B1 GGTLC2 LEPR GGT3P FCGBP GGTLC1 PKD1 CUZD1 PKHD1 ADAM17 PRKDC

1.16e-0385310115MP:0013558
MousePhenoabnormal thyroxine level

ITPRID2 GGTLC2 GGT3P GGTLC1

1.31e-03661014MP:0005469
MousePhenoabnormal skin adnexa physiology

ACER1 ATP7B MYO5A LEPR NF1 CUZD1

1.32e-031671016MP:0010680
MousePhenoincreased circulating creatinine level

ZNF354A TEAD3 NDUFS1 LEPR PIK3C2A PKD1 GPR176

1.35e-032291017MP:0005553
MousePhenodecreased pituitary hormone level

HMX3 GGTLC2 LEPR GGT3P GGTLC1

1.35e-031131015MP:0003972
MousePhenoabnormal long bone hypertrophic chondrocyte zone

GGTLC2 GGT3P GGTLC1 PKD1 ADAM17

1.35e-031131015MP:0000165
MousePhenopancreas fibrosis

PKD1 PKHD1

1.41e-0381012MP:0003334
MousePhenodilated pancreatic duct

PKD1 PKHD1

1.41e-0381012MP:0009144
MousePhenoincreased circulating amino acid level

ZNF354A TEAD3 NDUFS1 LEPR PRODH2 PIK3C2A PKD1 GPR176

1.41e-032981018MP:0014530
MousePhenoabnormal renal/urinary system physiology

FAT4 DRD5 ANO1 GGTLC2 WNK1 LEPR GGT3P PRODH2 PIK3C2A GGTLC1 PKD1 PKHD1 PRKDC

1.46e-0369510113MP:0005502
MousePhenoabnormal outer hair cell stereociliary bundle morphology

FAT4 ATP8B1 ADGRV1 NR2F1

1.47e-03681014MP:0004527
MousePhenoabnormal long bone epiphyseal plate proliferative zone

COMP GGTLC2 GGT3P GGTLC1

1.47e-03681014MP:0003662
MousePhenoabnormal lens morphology

NRCAM HIP1R GGTLC2 PKD1L2 NDUFS1 GGT3P HMCN1 GGTLC1 BUB1B ADAM17 AGAP7P AGAP4 AGAP6

1.54e-0369910113MP:0001303
MousePhenoabnormal long bone epiphyseal plate morphology

COMP GGTLC2 GGT3P GGTLC1 PKD1 ADAM17

1.54e-031721016MP:0003055
MousePhenoabnormal cartilage development

COMP GGTLC2 GGT3P GGTLC1 PKD1 ADAM17

1.54e-031721016MP:0000164
MousePhenoabnormal atrioventricular valve morphology

NF1 PKD1 ADAM17 KDM1A

1.55e-03691014MP:0002745
MousePhenosmall seminal vesicle

ATP8B1 GGTLC2 LEPR GGT3P GGTLC1

1.64e-031181015MP:0001157
MousePhenolethality during fetal growth through weaning, complete penetrance

FAT4 ATP7A ATP7B MYO5A ABCA12 HMX3 ANO1 TIMMDC1 BIRC6 SLC2A1 NR2F1 MAN1A2 NF1 BUB1B PKD1 B9D1 ADAM17 DYNC1H1 KDM1A

1.68e-03126910119MP:0011111
MousePhenoparalysis

ATP7A GGTLC2 GGT3P GGTLC1 DYNC1H1

1.70e-031191015MP:0000753
MousePhenoabnormal circulating mineral level

SLC26A3 ITCH ATP7A ATP7B CC2D1B DELE1 ATP8B1 TEAD3 WNK1 NDUFS1 LEPR PIK3C2A PRKDC AGAP7P AGAP4 AGAP6

1.74e-0398210116MP:0006357
MousePhenoabnormal estrous cycle

GGTLC2 LEPR NR2F2 GGT3P GGTLC1

1.76e-031201015MP:0001927
MousePhenodecreased kidney cell proliferation

FAT4 PKHD1

1.80e-0391012MP:0011441
DomainArfGap

ARFGAP2 AGAP7P AGAP4 AGAP6 ARAP2

1.57e-06291305SM00105
DomainARFGAP

ARFGAP2 AGAP7P AGAP4 AGAP6 ARAP2

1.57e-06291305PS50115
DomainArfGap

ARFGAP2 AGAP7P AGAP4 AGAP6 ARAP2

1.57e-06291305PF01412
DomainArfGAP

ARFGAP2 AGAP7P AGAP4 AGAP6 ARAP2

1.57e-06291305IPR001164
DomainGGT_peptidase

GGTLC2 GGT3P GGTLC1

1.13e-0571303IPR000101
DomainG_glu_transpept

GGTLC2 GGT3P GGTLC1

1.13e-0571303PF01019
DomainG_GLU_TRANSPEPTIDASE

GGTLC2 GGT3P GGTLC1

1.13e-0571303PS00462
DomainP-typ_ATPase_IB

ATP7A ATP7B

4.81e-0521302IPR027256
DomainHMA_Cu_ion-bd

ATP7A ATP7B

4.81e-0521302IPR006122
DomainSTAS

SLC26A3 SLC26A5 SLC26A9

5.22e-05111303PS50801
DomainSTAS

SLC26A3 SLC26A5 SLC26A9

5.22e-05111303PF01740
DomainSLC26A/SulP_fam

SLC26A3 SLC26A5 SLC26A9

5.22e-05111303IPR001902
DomainSTAS_dom

SLC26A3 SLC26A5 SLC26A9

5.22e-05111303IPR002645
DomainSLC26A/SulP_dom

SLC26A3 SLC26A5 SLC26A9

5.22e-05111303IPR011547
Domain-

SLC26A3 SLC26A5 SLC26A9

5.22e-051113033.30.750.24
DomainSulfate_transp

SLC26A3 SLC26A5 SLC26A9

5.22e-05111303PF00916
Domain-

PKD1L2 STAB1 PLA2R1 CLEC4F MRC2 PKD1

5.96e-059713063.10.100.10
DomainC-type_lectin-like/link

PKD1L2 STAB1 PLA2R1 CLEC4F MRC2 PKD1

6.68e-05991306IPR016186
DomainCTDL_fold

PKD1L2 STAB1 PLA2R1 CLEC4F MRC2 PKD1

1.03e-041071306IPR016187
DomainHeavy-metal-associated_CS

ATP7A ATP7B

1.44e-0431302IPR017969
DomainC_TYPE_LECTIN_1

PKD1L2 PLA2R1 CLEC4F MRC2 PKD1

2.39e-04801305PS00615
DomainEGF

FAT4 BRINP3 COMP MATN2 VWDE STAB1 FCGBP HMCN1

2.43e-042351308SM00181
DomainHMA

ATP7A ATP7B

2.86e-0441302PF00403
DomainREJ

PKD1L2 PKD1

2.86e-0441302PS51111
DomainREJ_dom

PKD1L2 PKD1

2.86e-0441302IPR014010
DomainHMA_2

ATP7A ATP7B

2.86e-0441302PS50846
DomainHMA_1

ATP7A ATP7B

2.86e-0441302PS01047
DomainLectin_C

PKD1L2 PLA2R1 CLEC4F MRC2 PKD1

3.01e-04841305PF00059
DomainCLECT

PKD1L2 PLA2R1 CLEC4F MRC2 PKD1

3.01e-04841305SM00034
DomainC_TYPE_LECTIN_2

PKD1L2 PLA2R1 CLEC4F MRC2 PKD1

3.18e-04851305PS50041
DomainC-type_lectin-like

PKD1L2 PLA2R1 CLEC4F MRC2 PKD1

3.35e-04861305IPR001304
Domain2Fe2S_fd_BS

AOX1 NDUFS1

4.74e-0451302IPR006058
DomainCOUP_TF

NR2F1 NR2F2

4.74e-0451302IPR003068
Domain2FE2S_FER_1

AOX1 NDUFS1

4.74e-0451302PS00197
Domain2FE2S_FER_2

AOX1 NDUFS1

7.08e-0461302PS51085
Domain2Fe-2S_ferredoxin-type

AOX1 NDUFS1

7.08e-0461302IPR001041
DomainPKD/REJ-like

PKD1L2 PKD1

7.08e-0461302IPR002859
DomainFer2

AOX1 NDUFS1

7.08e-0461302PF00111
DomainREJ

PKD1L2 PKD1

7.08e-0461302PF02010
DomainGrowth_fac_rcpt_

FAT4 BRINP3 COMP MATN2 STAB1 HMCN1

7.85e-041561306IPR009030
DomainAnoct_dimer

ANO4 ANO1

9.87e-0471302PF16178
DomainAnoct_dimer

ANO4 ANO1

9.87e-0471302IPR032394
DomainS04_transporter_CS

SLC26A3 SLC26A5

9.87e-0471302IPR018045
DomainHMA_dom

ATP7A ATP7B

9.87e-0471302IPR006121
DomainGlyco_hydro_47

USF3 MAN1A2

1.31e-0381302IPR001382
Domain-

ATP7A ATP7B ATP8B1

1.41e-033213033.40.1110.10
Domain-

ATP7A ATP7B ATP8B1

1.41e-033213032.70.150.10
DomainNtn_hydrolases_N

GGTLC2 GFPT1 GGTLC1

1.54e-03331303IPR029055
DomainEGF_CA

FAT4 COMP MATN2 STAB1 HMCN1

1.64e-031221305SM00179
DomainGPS

ADGRV1 PKD1L2 PKD1

1.68e-03341303SM00303
DomainEGF-like_Ca-bd_dom

FAT4 COMP MATN2 STAB1 HMCN1

1.76e-031241305IPR001881
Domain-

MATN2 SEC24C HMCN1 C2

1.77e-037413043.40.50.410
DomainEGF-like_dom

FAT4 COMP MATN2 VWDE STAB1 FCGBP HMCN1

1.81e-032491307IPR000742
DomainATPase_P-typ_cyto_domN

ATP7A ATP7B ATP8B1

1.83e-03351303IPR023299
DomainGPS

ADGRV1 PKD1L2 PKD1

1.83e-03351303PF01825
DomainATPase_P-typ_P_site

ATP7A ATP7B ATP8B1

1.99e-03361303IPR018303
DomainP_typ_ATPase

ATP7A ATP7B ATP8B1

1.99e-03361303IPR001757
DomainGPS

ADGRV1 PKD1L2 PKD1

1.99e-03361303PS50221
DomainATPASE_E1_E2

ATP7A ATP7B ATP8B1

1.99e-03361303PS00154
DomainA2M

CD109 PZP

2.09e-03101302PF00207
DomainA2M_N_2

CD109 PZP

2.09e-03101302IPR011625
DomainA2M_comp

CD109 PZP

2.09e-03101302IPR011626
DomainAnoctamin

ANO4 ANO1

2.09e-03101302PF04547
DomainAnoctamin

ANO4 ANO1

2.09e-03101302IPR007632
DomainA2M_recep

CD109 PZP

2.09e-03101302PF07677
DomainA2M_comp

CD109 PZP

2.09e-03101302PF07678
DomainSLC26A

SLC26A3 SLC26A5

2.09e-03101302PS01130
DomainA2M_N

CD109 PZP

2.09e-03101302PF01835
DomainA2M_N

CD109 PZP

2.09e-03101302IPR002890
DomainA-macroglobulin_rcpt-bd

CD109 PZP

2.09e-03101302IPR009048
DomainALPHA_2_MACROGLOBULIN

CD109 PZP

2.09e-03101302PS00477
DomainA2M_N_2

CD109 PZP

2.09e-03101302PF07703
DomainMacroglobln_a2

CD109 PZP

2.09e-03101302IPR001599
DomainATPase_P-typ_transduc_dom_A

ATP7A ATP7B ATP8B1

2.15e-03371303IPR008250
DomainGPS

ADGRV1 PKD1L2 PKD1

2.15e-03371303IPR000203
DomainE1-E2_ATPase

ATP7A ATP7B ATP8B1

2.15e-03371303PF00122
DomainIG_LIKE

CD244 NRCAM OBSL1 LEPR SEMA4G KIRREL3 IGSF22 HMCN1 IGHG2 AMIGO2

2.30e-0349113010PS50835
DomainEGF-like_CS

FAT4 COMP MATN2 VWDE STAB1 HMCN1 ADAM17

2.36e-032611307IPR013032
DomainGFP-like

STAB1 HMCN1

2.54e-03111302IPR023413
Domain-

STAB1 HMCN1

2.54e-031113022.40.155.10
DomainPKD_channel

PKD1L2 PKD1

2.54e-03111302PF08016
DomainPKD1_2_channel

PKD1L2 PKD1

2.54e-03111302IPR013122
DomainIg-like_dom

CD244 NRCAM OBSL1 LEPR SEMA4G KIRREL3 IGSF22 HMCN1 IGHG2 AMIGO2

2.74e-0350313010IPR007110
DomainABC_A

ABCA12 ABCA13

3.03e-03121302IPR026082
DomainEGF_CA

FAT4 COMP MATN2 HMCN1

3.06e-03861304PF07645
DomainAAA

ABCA12 ABCA13 NTPCR CLPX DYNC1H1

3.36e-031441305SM00382
DomainAAA+_ATPase

ABCA12 ABCA13 NTPCR CLPX DYNC1H1

3.36e-031441305IPR003593
Domain-

PLA2R1 MRC2

3.57e-031313022.10.10.10
DomainIg-like_fold

CD244 NRCAM OBSL1 LEPR SEMA4G KIRREL3 IGSF22 HMCN1 PTPRJ IGHG2 PKHD1 AMIGO2

3.82e-0370613012IPR013783
DomainFN_type2_col-bd

PLA2R1 MRC2

4.14e-03141302IPR000562
DomainFN2_2

PLA2R1 MRC2

4.14e-03141302PS51092
Domain-

AOX1 NDUFS1

4.14e-031413023.10.20.30
DomainFN2_1

PLA2R1 MRC2

4.14e-03141302PS00023
DomainBeta-grasp_dom

AOX1 NDUFS1

4.14e-03141302IPR012675
Domainfn2

PLA2R1 MRC2

4.14e-03141302PF00040
DomainFN2

PLA2R1 MRC2

4.14e-03141302SM00059
Domain-

ZYG11A PIK3R4 NF1 PRKDC MED12 TANGO6

4.63e-0322213061.25.10.10
DomainPI3/4_kinase_CS

PIK3C2A PRKDC

4.76e-03151302IPR018936
DomainVWF_A

MATN2 SEC24C HMCN1 C2

5.07e-03991304IPR002035
DomainGRAM

TBC1D9 SBF2

5.41e-03161302SM00568
Pubmed

The human gamma-glutamyltransferase gene family.

GGTLC2 GGT3P GGTLC3 GGTLC1

1.93e-0714132418357469
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

DOCK3 CC2D1B DELE1 WNK1 BIRC6 SEMA4G TBC1D9 USF3 SBF2 MED12 TANGO6 CCSER1

4.32e-074931321215368895
Pubmed

Phenotypic characterization of Ggt1(dwg/dwg) mice,a mouse model for hereditary γ-glutamyltransferase deficiency.

GGTLC2 GGT3P GGTLC1

5.31e-075132323615310
Pubmed

gamma-glutamyltranspeptidase-deficient knockout mice as a model to study the relationship between glutathione status, mitochondrial function, and cellular function.

GGTLC2 GGT3P GGTLC1

5.31e-075132311003618
Pubmed

Gamma-glutamyl transpeptidase gene organization and expression: a comparative analysis in rat, mouse, pig and human species.

GGTLC2 GGT3P GGTLC1

5.31e-075132310392451
Pubmed

Hyperoxia-induced lung injury in gamma-glutamyl transferase deficiency is associated with alterations in nitrosative and nitrative stress.

GGTLC2 GGT3P GGTLC1

5.31e-075132319850887
Pubmed

Reversible skeletal abnormalities in gamma-glutamyl transpeptidase-deficient mice.

GGTLC2 GGT3P GGTLC1

5.31e-075132312810527
Pubmed

Growth retardation and cysteine deficiency in gamma-glutamyl transpeptidase-deficient mice.

GGTLC2 GGT3P GGTLC1

5.31e-07513238755578
Pubmed

Reproductive defects in gamma-glutamyl transpeptidase-deficient mice.

GGTLC2 GGT3P GGTLC1

5.31e-075132311089562
Pubmed

N-acetyl-cysteine prevents age-related hearing loss and the progressive loss of inner hair cells in γ-glutamyl transferase 1 deficient mice.

GGTLC2 GGT3P GGTLC1

5.31e-075132326977590
Pubmed

Gamma-glutamyl transferase deficiency results in lung oxidant stress in normoxia.

GGTLC2 GGT3P GGTLC1

5.31e-075132312225953
Pubmed

Identification of a sixth promoter that directs the transcription of gamma-glutamyl transpeptidase type III RNA in mouse.

GGTLC2 GGT3P GGTLC1

5.31e-07513237775425
Pubmed

Mice with genetic gamma-glutamyl transpeptidase deficiency exhibit glutathionuria, severe growth failure, reduced life spans, and infertility.

GGTLC2 GGT3P GGTLC1

5.31e-07513239139708
Pubmed

Analysis of site-specific glycosylation of renal and hepatic γ-glutamyl transpeptidase from normal human tissue.

GGTLC2 GGT3P GGTLC1

5.31e-075132320622017
Pubmed

Accelerated methylmercury elimination in gamma-glutamyl transpeptidase-deficient mice.

GGTLC2 GGT3P GGTLC1

5.31e-07513239546365
Pubmed

gamma-Glutamyl transpeptidase. What does the organization and expression of a multipromoter gene tell us about its functions?

GGTLC2 GGT3P GGTLC1

5.31e-07513237485380
Pubmed

Accumulation of DNA damage in the organs of mice deficient in gamma-glutamyltranspeptidase.

GGTLC2 GGT3P GGTLC1

5.31e-075132310751614
Pubmed

Type VI RNA is the major gamma-glutamyl transpeptidase RNA in the mouse small intestine.

GGTLC2 GGT3P GGTLC1

5.31e-07513237523374
Pubmed

Cardio-reno-hepatic interactions in acute heart failure: the role of γ-glutamyl transferase.

GGTLC2 GGT3P GGTLC1

5.31e-075132324698228
Pubmed

gamma-Glutamyl transferase (GGT) deficiency in the GGTenu1 mouse results from a single point mutation that leads to a stop codon in the first coding exon of GGT mRNA.

GGTLC2 GGT3P GGTLC1

5.31e-075132310474818
Pubmed

Lung lining fluid glutathione attenuates IL-13-induced asthma.

GGTLC2 GGT3P GGTLC1

5.31e-075132318063838
Pubmed

Gamma-glutamyltranspeptidase knockout mice as a model for understanding the consequences of diminished glutathione on T cell-dependent immune responses.

GGTLC2 GGT3P GGTLC1

5.31e-075132310940879
Pubmed

Cataract development in gamma-glutamyl transpeptidase-deficient mice.

GGTLC2 GGT3P GGTLC1

5.31e-075132311095909
Pubmed

Expression of gamma-glutamyl transpeptidase in midgestation mouse yolk sac and mouse visceral yolk sac carcinoma cells.

GGTLC2 GGT3P GGTLC1

5.31e-07513237641802
Pubmed

The mouse skin carcinogenesis model.

GGTLC2 GGT3P GGTLC1

5.31e-07513239627710
Pubmed

Gamma-glutamyl transpeptidase and its role in melanogenesis: redox reactions and regulation of tyrosinase.

GGTLC2 GGT3P GGTLC1

5.31e-075132312453183
Pubmed

Immunocytochemical localization of gamma-glutamyltranspeptidase during fetal development of mouse kidney.

GGTLC2 GGT3P GGTLC1

5.31e-07513232891746
Pubmed

Liver-Specific Overexpression of Gamma-Glutamyltransferase Ameliorates Insulin Sensitivity of Male C57BL/6 Mice.

GGTLC2 GGT3P GGTLC1

5.31e-075132328660214
Pubmed

Bleomycin-induced pulmonary fibrosis is attenuated in gamma-glutamyl transpeptidase-deficient mice.

GGTLC2 GGT3P GGTLC1

5.31e-075132312468440
Pubmed

Cloning of cDNA and genomic structure of the mouse gamma-glutamyl transpeptidase-encoding gene.

GGTLC2 GGT3P GGTLC1

5.31e-07513238566783
Pubmed

Therapeutic Effect of GGsTop, Selective Gamma-glutamyl Transpeptidase Inhibitor, on a Mouse Model of 5-Fluorouracil-induced Oral Mucositis.

GGTLC2 GGT3P GGTLC1

5.31e-075132330591459
Pubmed

In vivo reversal of glutathione deficiency and susceptibility to in vivo dexamethasone-induced apoptosis by N-acetylcysteine and L-2-oxothiazolidine-4-carboxylic acid, but not ascorbic acid, in thymocytes from gamma-glutamyltranspeptidase-deficient knockout mice.

GGTLC2 GGT3P GGTLC1

5.31e-075132311795900
Pubmed

Inhibiting lung lining fluid glutathione metabolism with GGsTop as a novel treatment for asthma.

GGTLC2 GGT3P GGTLC1

5.31e-075132325132819
Pubmed

Characterization of the dwg mutations: dwg and dwg(Bayer) are new mutant alleles of the Ggt1 gene.

GGTLC2 GGT3P GGTLC1

5.31e-075132319760322
Pubmed

Gamma-glutamyltranspeptidase stimulates receptor activator of nuclear factor-kappaB ligand expression independent of its enzymatic activity and serves as a pathological bone-resorbing factor.

GGTLC2 GGT3P GGTLC1

1.06e-066132314634009
Pubmed

Six mRNAs with different 5' ends are encoded by a single gamma-glutamyltransferase gene in mouse.

GGTLC2 GGT3P GGTLC1

1.06e-06613238101000
Pubmed

Mapping of human gamma-glutamyl transpeptidase genes on chromosome 22 and other human autosomes.

GGTLC2 GGT3P GGTLC1

1.06e-06613238104871
Pubmed

Disruption of gamma-glutamyl leukotrienase results in disruption of leukotriene D(4) synthesis in vivo and attenuation of the acute inflammatory response.

GGTLC2 GGT3P GGTLC1

1.06e-066132311463821
Pubmed

Effect of atorvastatin on the expression of gamma-glutamyl transferase in aortic atherosclerotic plaques of apolipoprotein E-knockout mice.

GGTLC2 GGT3P GGTLC1

1.06e-066132325326709
Pubmed

Gamma-glutamyl leukotrienase, a novel endothelial membrane protein, is specifically responsible for leukotriene D(4) formation in vivo.

GGTLC2 GGT3P GGTLC1

1.06e-066132312163373
Pubmed

Ablation of Mrds1/Ofcc1 induces hyper-γ-glutamyl transpeptidasemia without abnormal head development and schizophrenia-relevant behaviors in mice.

GGTLC2 GGT3P GGTLC1

1.06e-066132322242126
Pubmed

Overexpression of gamma-glutamyltransferase in transgenic mice accelerates bone resorption and causes osteoporosis.

GGTLC2 GGT3P GGTLC1

1.06e-066132317363454
Pubmed

Four distinct membrane-bound dipeptidase RNAs are differentially expressed and show discordant regulation with gamma-glutamyl transpeptidase.

GGTLC2 GGT3P GGTLC1

1.06e-06613238663190
Pubmed

Transcriptional profiling and therapeutic targeting of oxidative stress in neuroinflammation.

GGTLC2 GGT3P GGTLC1

1.85e-067132332284594
Pubmed

m6A eraser FTO modulates autophagy by targeting SQSTM1/P62 in the prevention of canagliflozin against renal fibrosis.

GGTLC2 GGT3P GGTLC1

1.85e-067132336685533
Pubmed

γ-Glutamyltranspeptidase is an endogenous activator of Toll-like receptor 4-mediated osteoclastogenesis.

GGTLC2 GGT3P GGTLC1

1.85e-067132327775020
Pubmed

Defective epidermal growth factor gene expression in mice with polycystic kidney disease.

GGTLC2 GGT3P GGTLC1

1.85e-06713231968405
Pubmed

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.

FAT4 ITCH COMP MYO5A GGTLC2 GGT3P SERPINA4 FCGBP HMCN1 PTPRJ GGTLC3 IGHG2 GNA13 C2 PZP DYNC1H1

3.22e-0610701321623533145
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

SMARCA5 ITCH MYO5A HIP1R CLPX BIRC6 NDUFS1 GFPT1 SLC2A1 PIK3R4 NF1 SEC24C CDC40 PIK3C2A PRKDC MED12 DYNC1H1 KDM1A

3.84e-0613531321829467282
Pubmed

GGAPs, a new family of bifunctional GTP-binding and GTPase-activating proteins.

AGAP7P AGAP4 AGAP6

4.41e-069132312640130
Pubmed

Physiological roles and regulation of mammalian sulfate transporters.

SLC26A3 SLC26A5 SLC26A9

4.41e-069132311581495
Pubmed

AGAP1/AP-3-dependent endocytic recycling of M5 muscarinic receptors promotes dopamine release.

AGAP7P AGAP4 AGAP6

6.29e-0610132320664521
Pubmed

N-glycosylation and topology of the human SLC26 family of anion transport membrane proteins.

SLC26A3 SLC26A5 SLC26A9

6.29e-0610132324647542
Pubmed

Renalase regulates renal dopamine and phosphate metabolism.

GGTLC2 GGT3P GGTLC1

6.29e-0610132323863468
Pubmed

Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

NRCAM CD109 LEPR SERPINA4 FCGBP PTPRJ C2 PZP

6.67e-06257132816335952
Pubmed

AGAP1, a novel binding partner of nitric oxide-sensitive guanylyl cyclase.

AGAP7P AGAP4 AGAP6

8.62e-0611132315381706
Pubmed

Defining the membrane proteome of NK cells.

ITCH ATP7A ATP7B MYO5A NTPCR BIRC6 PIK3R4 MAN1A2 NF1 PIK3C2A GNA13 ADAM17 PRKDC AKAP1 MED12 DYNC1H1

9.66e-0611681321619946888
Pubmed

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.

NRCAM MYO5A NF1 GNA13 AGAP7P AGAP4 AGAP6 DYNC1H1

1.27e-05281132828706196
Pubmed

COUP-TFI and -TFII nuclear receptors are expressed in amacrine cells and play roles in regulating the differentiation of retinal progenitor cells.

NR2F1 NR2F2

1.43e-052132219766631
Pubmed

Copper efflux transporters ATP7A and ATP7B: Novel biomarkers for platinum drug resistance and targets for therapy.

ATP7A ATP7B

1.43e-052132229394468
Pubmed

Expression of the Menkes gene homologue in mouse tissues lack of effect of copper on the mRNA levels.

ATP7A ATP7B

1.43e-05213228082762
Pubmed

Solution structures of the actuator domain of ATP7A and ATP7B, the Menkes and Wilson disease proteins.

ATP7A ATP7B

1.43e-052132219645496
Pubmed

Systemic Reduction of Glut1 Normalizes Retinal Dysfunction, Inflammation, and Oxidative Stress in the Retina of Spontaneous Type 2 Diabetic Mice.

SLC2A1 LEPR

1.43e-052132237062410
Pubmed

Differential intracellular localisation of the Menkes and Wilson copper transporting ATPases in the third trimester human placenta.

ATP7A ATP7B

1.43e-052132221115196
Pubmed

Novel NR2F1 variants likely disrupt DNA binding: molecular modeling in two cases, review of published cases, genotype-phenotype correlation, and phenotypic expansion of the Bosch-Boonstra-Schaaf optic atrophy syndrome.

NR2F1 NR2F2

1.43e-052132228963436
Pubmed

Neurofibromin interacts with the cytoplasmic Dynein Heavy Chain 1 in melanosomes of human melanocytes.

NF1 DYNC1H1

1.43e-052132223583712
Pubmed

TMEM16A drives renal cyst growth by augmenting Ca2+ signaling in M1 cells.

ANO1 PKD1

1.43e-052132232185407
Pubmed

Mechanisms of charge transfer in human copper ATPases ATP7A and ATP7B.

ATP7A ATP7B

1.43e-052132228164426
Pubmed

Biochemical basis of regulation of human copper-transporting ATPases.

ATP7A ATP7B

1.43e-052132217562324
Pubmed

Genes regulating copper metabolism.

ATP7A ATP7B

1.43e-05213229823011
Pubmed

Molecular pathogenesis of Wilson and Menkes disease: correlation of mutations with molecular defects and disease phenotypes.

ATP7A ATP7B

1.43e-052132217717039
Pubmed

Localization of transcripts of the related nuclear orphan receptors COUP-TF I and ARP-1 in the adult mouse brain.

NR2F1 NR2F2

1.43e-05213227609634
Pubmed

Genetic polymorphisms of copper- and platinum drug-efflux transporters ATP7A and ATP7B in Japanese cancer patients.

ATP7A ATP7B

1.43e-052132220045993
Pubmed

Regulation of the apico-basolateral trafficking polarity of the homologous copper-ATPases ATP7A and ATP7B.

ATP7A ATP7B

1.43e-052132238032054
Pubmed

Molecular features of copper binding proteins involved in copper homeostasis.

ATP7A ATP7B

1.43e-052132227896900
Pubmed

The gene mutated in autosomal recessive polycystic kidney disease encodes a large, receptor-like protein.

PKD1 PKHD1

1.43e-052132211919560
Pubmed

Dynamics of the metal binding domains and regulation of the human copper transporters ATP7B and ATP7A.

ATP7A ATP7B

1.43e-052132228271598
Pubmed

Chemokinergic and Dopaminergic Signalling Collaborates through the Heteromer Formed by CCR9 and Dopamine Receptor D5 Increasing the Migratory Speed of Effector CD4+ T-Cells to Infiltrate the Colonic Mucosa.

DRD5 CCR9

1.43e-052132239337509
Pubmed

[Structure and function of ATP7A and ATP7B proteins--Cu-transporting ATPases].

ATP7A ATP7B

1.43e-052132221117320
Pubmed

USP38 inhibits colorectal cancer cell proliferation and migration via downregulating HMX3 ubiquitylation.

HMX3 USP38

1.43e-052132236204976
Pubmed

[From gene to disease: copper-transporting P ATPases alteration].

ATP7A ATP7B

1.43e-052132219046832
Pubmed

The deubiquitinase USP38 affects cellular functions through interacting with LSD1.

USP38 KDM1A

1.43e-052132230497519
Pubmed

Transgenic overexpression of GLUT1 in mouse glomeruli produces renal disease resembling diabetic glomerulosclerosis.

SLC2A1 LEPR

1.43e-052132220375117
Pubmed

Expression in mouse kidney of membrane copper transporters Atp7a and Atp7b.

ATP7A ATP7B

1.43e-052132212372948
Pubmed

Altered localisation of the copper efflux transporters ATP7A and ATP7B associated with cisplatin resistance in human ovarian carcinoma cells.

ATP7A ATP7B

1.43e-052132218565219
Pubmed

Copper transporting P-type ATPases and human disease.

ATP7A ATP7B

1.43e-052132212539960
Pubmed

An evolutionary conserved COUP-TF binding element in a neural-specific gene and COUP-TF expression patterns support a major role for COUP-TF in neural development.

NR2F1 NR2F2

1.43e-05213227708064
Pubmed

Chicken ovalbumin upstream promoter transcription factor (COUP-TF): expression during mouse embryogenesis.

NR2F1 NR2F2

1.43e-05213227626501
Pubmed

Cyst growth in ADPKD is prevented by pharmacological and genetic inhibition of TMEM16A in vivo.

ANO1 PKD1

1.43e-052132232859916
Pubmed

Hormonal regulation of the Menkes and Wilson copper-transporting ATPases in human placental Jeg-3 cells.

ATP7A ATP7B

1.43e-052132217109627
Pubmed

Quantitative relationship between mutated amino-acid sequence of human copper-transporting ATPases and their related diseases.

ATP7A ATP7B

1.43e-052132218688737
Pubmed

Akap1 deficiency exacerbates diabetic cardiomyopathy in mice by NDUFS1-mediated mitochondrial dysfunction and apoptosis.

NDUFS1 AKAP1

1.43e-052132232072193
Pubmed

Expression and localization of menkes and Wilson copper transporting ATPases in human placenta.

ATP7A ATP7B

1.43e-052132215135234
Pubmed

Developmental expression of the mouse mottled and toxic milk genes suggests distinct functions for the Menkes and Wilson disease copper transporters.

ATP7A ATP7B

1.43e-05213229215673
Pubmed

Pathogenicity analysis of novel variations in Chinese Han patients with polycystic kidney disease.

PKD1 PKHD1

1.43e-052132228578020
Pubmed

Spatiotemporal expression patterns of chicken ovalbumin upstream promoter-transcription factors in the developing mouse central nervous system: evidence for a role in segmental patterning of the diencephalon.

NR2F1 NR2F2

1.43e-05213228183930
Pubmed

Copper-transporting ATPases ATP7A and ATP7B: cousins, not twins.

ATP7A ATP7B

1.43e-052132218000748
Pubmed

[Expression and significance of GLUT-1 and DNA-PKcs in serous ovarian tumors].

SLC2A1 PRKDC

1.43e-052132217991316
Pubmed

Dynamic expression of COUP-TFI and COUP-TFII during development and functional maturation of the mouse inner ear.

NR2F1 NR2F2

1.43e-052132215907456
Pubmed

Requirement for COUP-TFI and II in the temporal specification of neural stem cells in CNS development.

NR2F1 NR2F2

1.43e-052132219160499
InteractionSCGB1D1 interactions

CD109 ADGRV1 VWDE LEPR SEMA4G IGHG2 MRC2 EPDR1

1.79e-061331258int:SCGB1D1
InteractionPRSS37 interactions

FAT4 CD109 ADGRV1 AKAP1

1.83e-06151254int:PRSS37
InteractionC19orf38 interactions

PLAAT1 HIP1R NR2F2 TBC1D9 NF1 PRKDC

1.58e-05861256int:C19orf38
InteractionIFNE interactions

FAT4 ACACB CD109 ADGRV1

2.22e-05271254int:IFNE
GeneFamilyCD molecules|Gamma-glutamyltransferases

GGTLC2 GGT3P GGTLC3 GGTLC1

4.93e-0713954564
GeneFamilyArfGAPs

ARFGAP2 AGAP7P AGAP4 AGAP6 ARAP2

7.61e-0733955395
GeneFamilyATPase copper transporting

ATP7A ATP7B

2.73e-0529521212
GeneFamilyImmunoglobulin like domain containing

CD244 NRCAM OBSL1 LEPR SEMA4G KIRREL3 AMIGO2

7.09e-05193957594
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

SBF2 GAB3 AGAP7P AGAP4 AGAP6 ARAP2

7.62e-04206956682
GeneFamilyC3 and PZP like, alpha-2-macroglobulin domain containing

CD109 PZP

9.60e-0499521234
GeneFamilyAnoctamins

ANO4 ANO1

1.20e-0310952865
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

NRCAM OBSL1 KIRREL3 IGSF22 HMCN1

1.60e-03161955593
GeneFamilyC-type lectin domain family

PLA2R1 CLEC4F MRC2

1.93e-0347953494
GeneFamilyATP binding cassette subfamily A

ABCA12 ABCA13

2.39e-0314952805
GeneFamilyX-linked mental retardation|Rho GTPase activating proteins|BAR-PH domain containing

AGAP4 AGAP6

3.53e-03179521291
GeneFamilyADAM metallopeptidase domain containing|CD molecules

CD244 CCR9 CD109 LEPR PTPRJ MRC2 ADAM17

4.73e-03394957471
CoexpressionAtlasDevelopingKidney_e15.5_Peripheral blastema_emap-27731_top-relative-expression-ranked_500

ANO4 FAT4 MYO5A ITPRID2 ADGRV1 PTGFR GFPT1 LEPR NR2F2 KIRREL3 PCDH11X AMIGO2

8.02e-0642112612gudmap_developingKidney_e15.5_Peripheral blastema_500
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6|TCGA-Prostate / Sample_Type by Project: Shred V9

SMARCA5 ADGRV1 BIRC6 NDUFS1 USF3 USP38 PIK3C2A SBF2 PRKDC DYNC1H1

3.31e-1019313210abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 NRCAM ABCA12 ABCA13 ADGRV1 PKD1L2 HMCN1 PCDH11X PKHD1

4.33e-0918413292cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 NRCAM ABCA12 ABCA13 ADGRV1 PKD1L2 HMCN1 PCDH11X PKHD1

4.33e-091841329ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 NRCAM ABCA12 ABCA13 ADGRV1 PKD1L2 HMCN1 PCDH11X PKHD1

4.33e-0918413292b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ANO4 FAT4 BRINP3 COMP NRCAM ANO1 NR2F1 HMCN1 GPR176

6.87e-0919413298fae8061b350336299aa81f378e07deadbd55123
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ANO4 FAT4 BRINP3 COMP NRCAM ANO1 NR2F1 HMCN1 GPR176

6.87e-0919413294d7d24390fdb379f943ddcc70a63f23955e10163
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ANO4 DOCK3 FAT4 COMP NRCAM ANO1 NR2F1 MRC2

7.07e-081811328d7e04e0ca549eac6d9b1192b6578f9b54943d54f
ToppCellPCW_13-14-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

HIP1R SLC26A9 ADGRV1 VWDE SLC2A1 FCGBP PKHD1 CCSER1

8.73e-081861328bb0bfe9a015151be08a6ffc5d82896d0556d76de
ToppCellPCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

DOCK3 NRCAM HIP1R ADGRV1 VWDE PKHD1 HDC CCSER1

1.03e-071901328625c08a0e5227efc46daa512fd579c3938ff76c7
ToppCellControl_saline-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|Control_saline / Treatment groups by lineage, cell group, cell type

ANO4 FAT4 MATN2 NR2F2 MRC2 PCDH11X GAB3 PZP

1.52e-072001328a799fc7bb83ad0524362cb5010df949741fb7bf3
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK3 RBM44 SLC26A3 ABCA13 SLC26A5 ADGRV1 PKHD1

2.63e-07145132796712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCell3'-Child04-06-SmallIntestine-Epithelial-Tuft-related-Tuft|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NRCAM ABCA13 HIP1R OBSL1 PTPRJ TAS1R1 CCSER1

1.36e-061851327686ed7550c6acd18e71e0076936ec5b07389adbd
ToppCellControl-Fibroblasts-Other_FB|Control / group, cell type (main and fine annotations)

ANO4 FAT4 BRINP3 NRCAM LEPR NR2F1 HMCN1

1.46e-061871327bd3739c4a52aa1ba5deffd778e113a9800f7e158
ToppCellMesenchymal-myofibroblast_cell|World / Lineage, Cell type, age group and donor

ANO4 DOCK3 FAT4 BRINP3 NRCAM ANO1 NR2F1

1.56e-06189132744e37f88137bb249933eb615235b2cf2ae7f3925
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

DOCK3 NRCAM ADGRV1 VWDE PKHD1 ARAP2 CCSER1

1.56e-0618913277659c7bbd58ee959a159294fb8d17317bbcc5681
ToppCell5'-Adult-LargeIntestine-Epithelial-Tuft-related-Tuft|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NRCAM HMX3 HIP1R OBSL1 PTPRJ TAS1R1 CCSER1

1.68e-06191132754f07e4de61735051498846afb44b1798bed8144
ToppCellCOVID-19-Heart-EC_(POSTN)|Heart / Disease (COVID-19 only), tissue and cell type

MATN2 LEPR NR2F1 PLA2R1 HMCN1 PIK3C2A PCDH11X

1.74e-061921327c0c34785a7bdf461722029b322e9184e3d9b3c26
ToppCellPCW_07-8.5-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

DOCK3 NRCAM HIP1R ADGRV1 BUB1B PKHD1 CCSER1

1.74e-06192132725378b5e4b0cea8415ff125783511fc25a56fc00
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ANO4 DOCK3 FAT4 BRINP3 NRCAM NR2F1 NR2F2

1.74e-06192132772881b280a415e65f87a80ca1369cbb0b722a0c4
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic-Fibro_myofibroblast|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ANO4 FAT4 BRINP3 COMP NRCAM NR2F1 HMCN1

2.06e-0619713276d0d68d460243a0259ada93ebda40fa7b3088eeb
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

SLC26A3 BIRC6 NF1 PTPRJ SBF2 PAN3 CCSER1

2.20e-06199132794b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c09-SLC4A10|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ZNF354A SLC26A5 TEAD3 KIRREL3 CUZD1 PZP

6.69e-061541326e94cd11488003347120eacd3ced0a8923ed09ccc
ToppCell5'-Adult-SmallIntestine-Epithelial-Tuft-related-Tuft|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NRCAM HMX3 HIP1R PTPRJ TAS1R1 CCSER1

1.10e-0516813268072d0496b7b730c4601009eaa69ec5366d26d73
ToppCellCOVID-19-Heart-CM_+_Macrophage|Heart / Disease (COVID-19 only), tissue and cell type

DOCK3 MYO5A STAB1 FCGBP PTPRJ CCSER1

1.18e-0517013264232fe937909f93d3736988c707b8f95ce993398
ToppCell5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NRCAM ANO1 ATP8B1 TEAD3 SEMA4G HMCN1

1.22e-051711326121e63ca281ad765d76c2afb3b4d441329b47f81
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

WNK1 PTGFR TBC1D9 FCGBP HMCN1 PKHD1

1.30e-0517313260c74bdb40e635d906fd180412c23bf7fed61621e
ToppCelldroplet-Liver-Npc-18m-Myeloid-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PKD1L2 TBC1D9 FABP7 CLEC4F PTPRJ ADAM17

1.30e-0517313269ba55e21d1037ec3150d77895e52f0b051df65da
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FAT4 COMP NRCAM ANO1 NR2F1 HMCN1

1.39e-0517513261799a7be623dc3bf53ba580a7c47d2619969d708
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FAT4 COMP ANO1 HMCN1 MRC2 GPR176

1.43e-0517613269bc87cd5cda2372e1bce94c9dfd408eb1dfd8d0c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FAT4 COMP ANO1 HMCN1 MRC2 GPR176

1.43e-0517613263f8274a7ab67f9f8a8923193763a5543cfe4defa
ToppCellnormal_Pleural_Fluid-Myeloid_cells-CD163+CD14+_DCs|normal_Pleural_Fluid / Location, Cell class and cell subclass

NTPCR CD109 STK32C LEPR BUB1B EPDR1

1.43e-0517613267a74217b7fa1032b918f00a3972dff5fab74671a
ToppCellChildren_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

ANO4 DOCK3 FAT4 BRINP3 NRCAM ANO1

1.48e-051771326b59967219f7d874805768e247c0eb2bc4d4420c8
ToppCelldroplet-Marrow-nan-18m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC26A3 CD244 ATP8B1 PTGFR TMPRSS7 HDC

1.68e-051811326382337427be3c11ecd03e9fa2c2e831a9674c6a7
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FAT4 BRINP3 COMP AOX1 HMCN1 PCDH11X

1.68e-051811326b116c68393d8836bac080f81a8fcbeb52e0403e7
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANO4 FAT4 ANO1 OBSL1 PTGFR NR2F2

1.90e-0518513260b5a0df58ae2ad8261f40f152775747af4f3937a
ToppCellLV-10._Endothelium_II|World / Chamber and Cluster_Paper

SLC26A3 ATP8B1 LEPR HMCN1 PIK3C2A PCDH11X

2.02e-0518713267876dcb4800c2e54874df3d933efb79307a64a97
ToppCellPCW_10-12-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

MYO5A HIP1R ADGRV1 VWDE PKHD1 CCSER1

2.02e-051871326db2974e2e87ac9f1c2407a371d5ed89af09fc9b7
ToppCell-Unknown-Endothelial-Myofibroblast| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ANO4 DOCK3 NRCAM HMCN1 EPDR1 KDM1A

2.08e-0518813266468fa95ad0395395301115286f2d8c0df5d3882
ToppCell-Unknown-Endothelial| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ANO4 DOCK3 NRCAM HMCN1 EPDR1 KDM1A

2.08e-0518813267a81ac5c79c3eb26639b52d2b9fd5e7ef9798fd6
ToppCell-Unknown| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ANO4 DOCK3 NRCAM HMCN1 EPDR1 KDM1A

2.08e-0518813269cb718bfe1358c6fd842f096e228eb0abb9aefc6
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ANO4 DOCK3 MATN2 ANO1 NR2F2 PZP

2.14e-0518913267ab1cfc1657277858339f7258a0c4ae9cb42fdf8
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ANO4 DOCK3 ANO1 NR2F2 EPDR1 GPR176

2.14e-05189132645e588b2a4ad9e3ff74e22d9d627ed3571f3b8b8
ToppCellMesenchymal-airway_smooth_muscle_cell|World / Lineage, Cell type, age group and donor

ANO4 DOCK3 BRINP3 NRCAM ANO1 GPR176

2.21e-051901326645e56b02edc3702c7db917b8ecd5eed0decaf71
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ATP7A MATN2 NR2F1 NR2F2 FABP7 ARAP2

2.21e-051901326106862ef44fcaa0971c3ba0147d13eb08015ca77
ToppCellfacs-Heart-RA-3m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANO1 NR2F1 NR2F2 FABP7 PLA2R1 AMIGO2

2.21e-051901326bfbdf16d488359d7935a419c4c1823288f39c183
ToppCellP15-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_vein|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

NR2F2 KIRREL3 HMCN1 PTPRJ AMIGO2 HDC

2.21e-051901326d072bb285bd34d518b958e7c9ad44739c60b359c
ToppCellfacs-Heart-RA-3m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANO1 NR2F1 NR2F2 FABP7 PLA2R1 AMIGO2

2.21e-051901326eb1f8bb4d903b08e50c2dc173b06c0c79d8e316e
ToppCellFetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ANO1 ATP8B1 NR2F2 NT5C1A HMCN1 GPR176

2.21e-051901326d6b3a92119b210974a32af3fe9875d60eb02761e
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

DOCK3 ATP8B1 ADGRV1 PKHD1 ARAP2 CCSER1

2.27e-05191132660ff989fe99d243a3d52955223680cdd1f1917a4
ToppCellPCW_07-8.5-Epithelial-Epithelial_proliferating-epi_proliferating3_(5)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

DOCK3 NRCAM ADGRV1 PKHD1 HDC CCSER1

2.34e-051921326d3634574b2e8d2ded6446969361b70761b331aea
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NRCAM AOX1 NR2F1 NR2F2 MRC2 PZP

2.34e-0519213263d0cb19f037f604253d7d728689aeaa94251e92b
ToppCellPCW_07-8.5-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

DOCK3 NRCAM ATP8B1 ADGRV1 PKHD1 CCSER1

2.34e-051921326b99f8236ef4ccdc75c02abea381cae6453205f6f
ToppCellLPS-IL1RA-Stromal_mesenchymal|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NRCAM AOX1 NR2F1 NR2F2 MRC2 PZP

2.34e-0519213264e47a02007f562f29ba5910df64d32a0167d0bd1
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

FAT4 BRINP3 MATN2 AOX1 NR2F1 MRC2

2.34e-051921326e0f4e4470a71bfa81d9dcd8594e5f82aafc24f81
ToppCelldroplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l39|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ANO1 NR2F1 NR2F2 PLA2R1 C2 GPR176

2.41e-051931326d0dcc0c11ccf99ff6b07e456d25b9742649aadd8
ToppCellLPS-antiTNF-Endothelial-Endothelial-Gen_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAT4 CD109 ATP8B1 LEPR HMCN1 CCSER1

2.41e-0519313266e1982d089a9de628e6006d23ff78a223fbd9f47
ToppCellCOVID-19-kidney-CD-PC|kidney / Disease (COVID-19 only), tissue and cell type

NRCAM ATP8B1 PTGFR SLC2A1 PKHD1 CCSER1

2.41e-051931326738689d009e4b118d7ce3171a207294b95cbe78b
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NRCAM HIP1R TBC1D9 PTPRJ PKHD1 CCSER1

2.48e-05194132604bfc555743f7d8821439d05ae442d15e9886c59
ToppCellLV-10._Endothelium_II|LV / Chamber and Cluster_Paper

SLC26A3 ATP8B1 LEPR HMCN1 PIK3C2A PCDH11X

2.48e-051941326b6cc849fa08599bff9839ef382d190cc964e273e
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FAT4 MATN2 ANO1 NR2F1 NR2F2 MRC2

2.63e-051961326a12dd986df65c36f248cf10815c3b8b6238613b0
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MATN2 ANO1 NR2F1 NR2F2 HMCN1 MRC2

2.63e-051961326fa445f4240c521cf04eb2e2f79a5c55fda31209a
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MATN2 ANO1 NR2F1 NR2F2 HMCN1 MRC2

2.63e-051961326802f61e78a9a1030a86c4a980c398a73cd4d1574
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FAT4 MATN2 ANO1 NR2F1 NR2F2 MRC2

2.63e-0519613263e6803587d8566fd08cb8b290be3b6461743d79c
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ANO4 BRINP3 COMP NR2F1 PCDH11X GPR176

2.70e-05197132616758f181ef07c60aee63072e1da9572c5c85414
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FAT4 COMP MATN2 LEPR NR2F1 HMCN1

2.70e-05197132644673c38384453207871d3fd8e8ba9093cc06bc5
ToppCellCOVID-19-lung-Fibroblast|lung / Disease (COVID-19 only), tissue and cell type

NRCAM AOX1 NR2F1 PLA2R1 HMCN1 MRC2

2.78e-051981326df3de77216f5c5d6141ec44d01c56b942f611838
ToppCellTracheal-NucSeq-Stromal-Peri/Epineurial_-NAF_epineurial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MATN2 SLC2A1 LEPR NR2F1 NR2F2 MRC2

2.86e-0519913269c2db0bb94cba71a3cc1827844da090e213e0258
ToppCelldistal-3-mesenchymal-Myofibroblast|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ANO4 BRINP3 COMP NRCAM MATN2 NR2F1

2.86e-0519913261f20addc0d138fec02ed6ca4c518169c568de263
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

NRCAM AOX1 NR2F1 NR2F2 MRC2 PZP

2.86e-05199132630d3e8c0681ec11f86dd38c5f48d21187a1b4f90
ToppCellLPS_IL1RA-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

FAT4 ITPRID2 BIRC6 LEPR HMCN1 PIK3C2A

2.94e-052001326dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCellTracheal|World / Cell types per location group and 10X technology with lineage, and cell group designations

ANO1 ATP8B1 PLA2R1 FCGBP SBF2 CCSER1

2.94e-052001326682960e28542a3d6c119047cd0131941932cfdea
ToppCellTracheal-10x5prime-Stromal-Fibroblastic-Fibro_peribronchial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FAT4 COMP NR2F1 HMCN1 MRC2 GPR176

2.94e-0520013268ab0051544ea32eb8b3f7f8ba7582deaf8bf26c0
ToppCellNeuronal-Inhibitory-iA-iA_3(VIP)-VIP_3-CHRM2|Neuronal / cells hierarchy compared to all cells using T-Statistic

ANO4 FAT4 ANO1 OBSL1 PTGFR NR2F2

2.94e-052001326501a3b93624df463458a35d3e6648d4ccc941724
ToppCellNeuronal-Inhibitory-iA-iA_3(VIP)-VIP_3-CHRM2-L1-3|Neuronal / cells hierarchy compared to all cells using T-Statistic

ANO4 FAT4 ANO1 OBSL1 PTGFR NR2F2

2.94e-052001326d1f36a8232411933b1494168ec912fd0e5246428
ToppCellTracheal-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FAT4 AOX1 LEPR NR2F1 HMCN1 MRC2

2.94e-052001326b4ccffdd79526c85e5273d27b668dbddcddba1ee
ToppCellTracheal-NucSeq-Epithelial-Epi_submucosal-gland|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ANO1 ATP8B1 ADGRV1 GFPT1 PTPRJ CCSER1

2.94e-0520013260eb9ad8c0373bcc62029ec21c590ed03aaacd039
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Igfbp6_Pltp|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

FAT4 BRINP3 NR2F2 HMCN1 CCSER1

3.43e-05124132536dfc702a570e1a1a6dde09f38badf9023ea7287
ToppCellHippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1|Hippocampus / BrainAtlas - Mouse McCarroll V32

COMP CCR9 PTGFR LEPR C2

5.15e-0513513257e3559ed0fef7916d1938b4e1a9fa4456a60e3d3
ToppCellHippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1-Endothelial_Tip.Dcn.Agt_(Agt)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

COMP CCR9 PTGFR LEPR C2

5.15e-0513513254cb399620aa9edc2ca59e4df76ab7011ceb58db9
ToppCellHippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_2|Hippocampus / BrainAtlas - Mouse McCarroll V32

COMP CCR9 PTGFR LEPR C2

5.15e-0513513256bd2a0bfd8d20950f1b66810668682dc055a0ada
ToppCellHippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1-Endothelial_Tip.Dcn.Agt_(Agt)|Hippocampus / BrainAtlas - Mouse McCarroll V32

COMP CCR9 PTGFR LEPR C2

5.15e-05135132597989546826bf3739e1b86a10832a457fd37c5d2
ToppCell367C-Myeloid-Macrophage-SPP1+_Macrophage_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

RBM44 ABCA12 ADGRV1 TEAD3 CLEC4F

6.99e-0514413253ba7f8bd6d1c551048403c94693d63e60f7cbbb7
ToppCellCerebellum-Endothelial-ENDOTHELIAL_TIP|Cerebellum / BrainAtlas - Mouse McCarroll V32

COMP CCR9 PTGFR MRC2 C2

8.21e-0514913253980fa4f1986a2f164a1826ea043fb71f1d756cd
ToppCellTCGA-Thymus-Primary_Tumor-Thymoma-Type_AB-8|TCGA-Thymus / Sample_Type by Project: Shred V9

FAT4 LEPR PLA2R1 HMCN1 MRC2

8.75e-0515113255906562efd36fbcb91f96e0a0d3a8fe999ba1e79
ToppCellFrontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

COMP CCR9 AOX1 LEPR MRC2

9.60e-05154132565dbb60f636562eeba3dafadae9c0c7db2b27476
ToppCell10x3'2.3-week_17-19-Hematopoietic-HSC/MPP_and_pro-LMPP|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

CD244 CCR9 OBSL1 ADGRV1 CCSER1

1.02e-041561325331b63bf4744ab494c3959436a8a0d8a1e4c0de4
ToppCellHippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Fibcd1-Excitatory_Neuron.Slc17a7.Fibcd1-Lypd1_(CA1_Principal_cells_(Anterior))|Hippocampus / BrainAtlas - Mouse McCarroll V32

DRD5 MATN2 PRODH2 CDC40

1.14e-0484132452d167614afa9b056f2934142d3250fe5e70e806
ToppCell3'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CYB5RL LEPR NR2F2 TBC1D9 PZP

1.15e-04160132533050dc646762dc7e9dcc4a12c618e1ba1ce5a4d
ToppCellfacs-Pancreas-Exocrine-24m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COMP ACACB ABCA12 FCGBP CUZD1

1.18e-041611325b9a17f41426bf715f30bf544a6795afaf37a3aa6
ToppCellfacs-Pancreas-Exocrine-24m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COMP ACACB ABCA12 FCGBP CUZD1

1.18e-041611325f7a89c481f789f624102857be722c95fbeb47595
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-Tuft-related-Tuft|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NRCAM HMX3 PTPRJ PKHD1 CCSER1

1.18e-041611325f5df8c6a340d5026726804b103e32137f363ca40
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DOCK3 SLC26A3 ABCA13 ADGRV1 PKHD1

1.22e-041621325bf886e22ff2a20353499004b53f25fb9e6574896
ToppCellChildren_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

ANO4 DOCK3 FAT4 BRINP3 NRCAM

1.29e-041641325e3983f655cdba308fb192182829f17bef99ce0ba
ToppCellPND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ANO4 COMP CD109 STK32C STAB1

1.33e-04165132550a8513d8d2630861499393a7f102b35366bad37
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_TIP-Dcn_1|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

COMP CCR9 PTGFR LEPR MRC2

1.33e-041651325570483b43ccb5831feec9337b4664814431d40b1
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_TIP|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

COMP CCR9 PTGFR LEPR MRC2

1.33e-0416513252026a9a07f4d314cc05c167e491312b373468e46
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW19-Neuronal-GABAergic_neurons|GW19 / Sample Type, Dataset, Time_group, and Cell type.

ABCA12 NR2F1 NR2F2 PCDH11X

1.36e-048813245582fd7bac60c690ecd1f2aff1d446ccb69f79b9
ToppCelldroplet-Kidney-nan-18m-Epithelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 ANO1 NR2F1 PLA2R1 MRC2

1.48e-04169132587116c33c5ca8cb1862e103e5607b1df4d264569
ToppCell3'-Child09-12-SmallIntestine-Epithelial-Tuft-related-Tuft|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HMX3 HIP1R OBSL1 TAS1R1 CCSER1

1.48e-04169132505e12524d68d409fed386ffad233305683b4575b
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA12 ABCA13 ADGRV1 FABP7 PKHD1

1.48e-04169132512bdc709bc000d7f9061ecd9fbd57233eaacb7e2
Diseaseaflatoxins-related hepatocellular carcinoma (biomarker_via_orthology)

GGTLC2 GGT3P GGTLC3 GGTLC1

1.21e-0871294DOID:5022 (biomarker_via_orthology)
Diseasealcohol dependence (biomarker_via_orthology)

GGTLC2 GGT3P GGTLC3 GGTLC1

2.41e-0881294DOID:0050741 (biomarker_via_orthology)
Diseasecerebral palsy (implicated_via_orthology)

AGAP7P AGAP4 AGAP6

9.58e-06101293DOID:1969 (implicated_via_orthology)
DiseaseColorectal Carcinoma

ATP7B NRCAM ABCA12 ABCA13 CD109 STK32C WNK1 NF1 BUB1B PCDH11X PKHD1 PZP HDC

1.32e-0570212913C0009402
Diseaseoccipital horn syndrome (implicated_via_orthology)

ATP7A ATP7B

1.90e-0521292DOID:0111272 (implicated_via_orthology)
Diseasevery long-chain saturated fatty acid measurement

SLC26A9 ATP8B1 PIGC CCSER1

4.13e-05441294EFO_0006796
Diseasemetal metabolism disorder (implicated_via_orthology)

ATP7A ATP7B

1.13e-0441292DOID:896 (implicated_via_orthology)
DiseaseWilson disease (implicated_via_orthology)

ATP7A ATP7B

1.88e-0451292DOID:893 (implicated_via_orthology)
DiseaseMenkes disease (implicated_via_orthology)

ATP7A ATP7B

1.88e-0451292DOID:1838 (implicated_via_orthology)
DiseaseColorectal cancer

PTPRJ RAD54B BUB1B

2.21e-04271293cv:C0346629
DiseaseCOLORECTAL CANCER

PTPRJ RAD54B BUB1B

2.21e-04271293114500
DiseaseNeoplasm of the large intestine

PTPRJ RAD54B BUB1B

2.21e-04271293cv:C0009404
DiseaseSevere Congenital Microcephaly

SLC2A1 BUB1B DYNC1H1

3.35e-04311293C3853041
DiseaseMicrolissencephaly

SLC2A1 BUB1B DYNC1H1

4.05e-04331293C1956147
Diseasealcohol dependence, risky sexual behaviour measurement

IGSF22 CCSER1

5.22e-0481292EFO_0007877, MONDO_0007079
DiseaseColon Carcinoma

PTPRJ RAD54B

6.69e-0491292C0699790
Diseasespinal muscular atrophy (implicated_via_orthology)

ATP7A ATP7B

6.69e-0491292DOID:12377 (implicated_via_orthology)
DiseaseMalignant tumor of colon

ATP7A SLC2A1 PTPRJ RAD54B KDM1A

6.86e-041591295C0007102
Diseaseattention deficit hyperactivity disorder, conduct disorder

ATP8B1 PKD1L2 KIRREL3

7.17e-04401293EFO_0003888, EFO_0004216
DiseaseDisease Exacerbation

ATP7B ABCA13 NDUFS1 ARFGAP2 KDM1A

8.10e-041651295C0235874
DiseasePancreatic Ductal Adenocarcinoma

ACACB ABCA12

1.02e-03111292C1335302
DiseaseColorectal Neoplasms

ATP7B NRCAM ABCA12 ABCA13 CD109 BUB1B

1.41e-032771296C0009404
DiseaseDrug habituation

ANO4 NRCAM PLA2R1 TMPRSS7

1.66e-031151294C0013170
DiseaseDrug abuse

ANO4 NRCAM PLA2R1 TMPRSS7

1.66e-031151294C0013146
DiseasePrescription Drug Abuse

ANO4 NRCAM PLA2R1 TMPRSS7

1.66e-031151294C4316881
DiseaseSubstance-Related Disorders

ANO4 NRCAM PLA2R1 TMPRSS7

1.66e-031151294C0236969
DiseaseDrug Use Disorders

ANO4 NRCAM PLA2R1 TMPRSS7

1.66e-031151294C0013222
DiseaseDrug Dependence

ANO4 NRCAM PLA2R1 TMPRSS7

1.66e-031151294C1510472
DiseaseSubstance Dependence

ANO4 NRCAM PLA2R1 TMPRSS7

1.66e-031151294C0038580
DiseaseSubstance Use Disorders

ANO4 NRCAM PLA2R1 TMPRSS7

1.66e-031151294C0038586
DiseaseOrganic Mental Disorders, Substance-Induced

ANO4 NRCAM PLA2R1 TMPRSS7

1.66e-031151294C0029231
DiseaseSubstance abuse problem

ANO4 NRCAM PLA2R1 TMPRSS7

1.71e-031161294C0740858
Diseasefactor XI measurement, fibrinogen measurement, tissue plasminogen activator measurement, factor VII measurement

ITCH HECTD4 LEPR

1.91e-03561293EFO_0004619, EFO_0004623, EFO_0004694, EFO_0004791
Diseaseglycerate measurement

CCR9 HMCN1

1.92e-03151292EFO_0021029
Diseaseblood osmolality measurement

ABCA12 PKD1L2 PKHD1

2.11e-03581293EFO_0007967
DiseaseTremor, Rubral

ATP7A SLC2A1

2.19e-03161292C0750940
DiseaseAtaxia, Appendicular

ATP7A SLC2A1

2.19e-03161292C0750937
DiseaseAtaxia, Motor

ATP7A SLC2A1

2.19e-03161292C0278161
Diseaseneutrophil collagenase measurement

ABCA13 C2

2.19e-03161292EFO_0008248
DiseaseAtaxia, Sensory

ATP7A SLC2A1

2.19e-03161292C0240991
DiseaseAbnormal coordination

ATP7A SLC2A1

2.19e-03161292C0520966
Diseaseautosomal recessive polycystic kidney disease (implicated_via_orthology)

PKD1 PKHD1

2.19e-03161292DOID:0110861 (implicated_via_orthology)
DiseaseAtaxia, Truncal

ATP7A SLC2A1

2.19e-03161292C0427190
DiseaseMammary Carcinoma, Human

ATP7B NRCAM CD109 SLC2A1 LEPR NR2F1 FABP7 MED12

2.22e-035251298C4704874
DiseaseMammary Neoplasms, Human

ATP7B NRCAM CD109 SLC2A1 LEPR NR2F1 FABP7 MED12

2.22e-035251298C1257931
Diseasepuberty onset measurement

DOCK3 BIRC6 LEPR AKAP1

2.25e-031251294EFO_0005677
DiseaseMammary Neoplasms

ATP7B NRCAM CD109 SLC2A1 LEPR NR2F1 FABP7 MED12

2.27e-035271298C1458155
DiseaseInborn Errors of Metabolism

SLC2A1 LEPR

2.47e-03171292C0025521
DiseaseMoyamoya Disease

ATP7A NF1

2.47e-03171292C0026654
DiseaseBreast Carcinoma

ATP7B NRCAM CD109 SLC2A1 LEPR NR2F1 FABP7 MED12

2.58e-035381298C0678222
DiseaseMalignant neoplasm of breast

ATP7B NRCAM CD109 ATP8B1 WNK1 SLC2A1 LEPR NR2F1 FABP7 PIK3R4 NF1 MED12

2.68e-03107412912C0006142
DiseaseAge-related macular degeneration

HMCN1 C2

2.77e-03181292cv:C0242383
Diseaseamino acid measurement

FAT4 ACACB ABCA12 STK32C PTGFR PLA2R1 PTPRJ PRKDC CCSER1

3.02e-036781299EFO_0005134
DiseaseMicrocephaly

SLC2A1 BUB1B DYNC1H1

3.19e-03671293C0025958
Diseasevenous thromboembolism, fibrinogen measurement

HECTD4 LEPR PTPRJ

3.19e-03671293EFO_0004286, EFO_0004623
Diseaseattention deficit hyperactivity disorder (is_implicated_in)

DOCK3 DRD5

3.42e-03201292DOID:1094 (is_implicated_in)
Diseasejuvenile idiopathic arthritis

NRCAM ABCA13 TIMMDC1

4.22e-03741293EFO_0002609

Protein segments in the cluster

PeptideGeneStartEntry
QLDVFTLSGFRTVQI

BUB1B

921

O60566
ASTIFQRNSQTDVVE

AGAP4

86

Q96P64
QETFTINYSVILSTR

EPDR1

176

Q9UM22
TSEVVRIQSALQAFN

BRINP3

736

Q76B58
RAAFQIISQVISEAT

AKAP1

346

Q92667
LVSQVFLTGTFTQEV

CDY1

461

Q9Y6F8
QNFEVVSVSTISAVI

BIRC6

2846

Q9NR09
SLRDFTVTVIDQNTA

C2orf78

141

A6NCI8
ETVQVDTTNILFVAS

CLPX

406

O76031
SRDVVVSQSQLRVAF

NT5C1A

196

Q9BXI3
NRSQFIRLVFITTVV

ACER1

116

Q8TDN7
ISQTEVIIRFAFQTS

ATP7B

961

P35670
FLVSQTTLEEVFINF

ABCA12

2551

Q86UK0
VTLTDFRAFQTVVLD

COMP

526

P49747
AVQARSSVASLVIFV

FAT4

451

Q6V0I7
LIFEVGSRQQSISIF

ADGRV1

1061

Q8WXG9
IVTITEVNLVNSDFS

ADGRV1

3871

Q8WXG9
ITQDILERFQDTFTS

CFAP46

2436

Q8IYW2
QTFSQVSELVLNVTI

ABCA13

226

Q86UQ4
VDVTINVSNFTVSRS

AMIGO2

376

Q86SJ2
VSSQSFSEIERQAQV

ARFGAP2

236

Q8N6H7
NKFEVVTTQRTFVFR

ARAP2

541

Q8WZ64
ISLVQQSEFSLEVTQ

CCSER1

201

Q9C0I3
SVITNAFVIAITSDF

ANO4

781

Q32M45
SFAVTIASALVITVN

ATP8B1

1071

O43520
ASTIFQRNSQTDVVE

AGAP6

86

Q5VW22
VDQELFLTFVTSSRA

AOX1

606

Q06278
TETIIRFAFQASITV

ATP7A

981

Q04656
SVGITNVRTVFSNVF

PRODH2

16

Q9UF12
RITENVSFIFQNITT

RAD54B

891

Q9Y620
NTTSISVNKLFVRVF

PZP

406

P20742
TVTINQTVDVSTDFR

RBM44

461

Q6ZP01
LRNFSILEISFTTVS

OR6C1

61

Q96RD1
SLRTVSSSVIEQLFF

NR2F1

376

P10589
RTVSSSVIEQLFFVR

NR2F2

371

P24468
TNVFIVSLAVSDLFV

DRD5

76

P21918
REVFFINTQSIVQLV

ACACB

1101

O00763
QDRVSLTFTTSERVV

OBSL1

721

O75147
SVAIRSRENVVFVQT

OVOS1

96

Q6IE37
VTSFRNITQLSFQLI

OVOS1

156

Q6IE37
QDKLIIRFTVTSQFT

HDC

441

P19113
IRFTVTSQFTTRDDI

HDC

446

P19113
ASTFIAVVQAIVRTA

GGT3P

536

A6NGU5
EFRTNAIQVFDVTAV

PTPRJ

361

Q12913
VFLVANFSQIETLTS

MATN2

216

O00339
RQFTTTVQVVIFIGS

GPR176

41

Q14439
TIIFSNVQERSSAVY

NRCAM

416

Q92823
VNTAFTVVSLFVVER

SLC2A1

316

P11166
SENTDIANSVVRFIT

SBF2

806

Q86WG5
QNNFVFIVKTTSRTF

GAB3

81

Q8WWW8
RTVFSRSQVFQLEST

HMX3

231

A6NHT5
SFEINVSVAIITFAS

C2

286

P06681
TCQTENRLSVFFSVI

PTGFR

21

P43088
QTTDAEATIFFTRLI

PIK3C2A

1361

O00443
QITSTFIAVVQAIVR

GGTLC1

191

Q9BX51
TRTVFSRSQVFQLES

HMX1

206

Q9NP08
RTFFVLSQESSSEQL

CYB5RL

241

Q6IPT4
LVTITNRFEQAFVSS

MRC2

556

Q9UBG0
FVSTVNSLVFQQIDA

LEPR

111

P48357
AQVSRNVLEQITSFA

MED12

846

Q93074
FSQLFIQAVRQTLST

NTPCR

121

Q9BSD7
ASTFIAVVQAIVRTA

GGTLC2

186

Q14390
TTFIRVTQQVNPIFS

GMPR2

331

Q9P2T1
LAVIINAFVISFTSD

ANO1

796

Q5XXA6
IFETIVNNRVFSNVS

GNA13

271

Q14344
FTTAINTENIRLVFR

GNA13

346

Q14344
SLFSVVIVNLFVNES

PCDH11X

761

Q9BZA7
VIVNLFVNESVTNAT

PCDH11X

766

Q9BZA7
ILTVSVVNQSLFDTQ

HECTD4

3211

Q9Y4D8
ETIVFISAATNLVFS

OR8J3

196

Q8NGG0
RQIEVLTTVANAFSS

ITPRID2

241

P28290
NDFVLTVVISATNRA

PKD1L2

836

Q7Z442
QIASTFIAVVQAIVR

GGTLC3

191

B5MD39
SENLTVVVNNFISLT

HMCN1

2971

Q96RW7
SSIITDQFVARAAIF

OR56A5

136

P0C7T3
VANILESRQSFVFIV

PPCS

256

Q9HAB8
SNIVTLREVFTTKAF

PAN3

546

Q58A45
TVTRKTLFEDSFQQI

ITCH

551

Q96J02
VTGISRNVSTNVFFK

CD109

331

Q6YHK3
ESVFRQLNTAIAVSQ

HIP1R

191

O75146
SIVEFFSLVTRSSNI

IGSF22

46

Q8N9C0
EVIAVNTRSTSQTFI

KDM1A

601

O60341
FRSSIQELFQSIRFV

DOCK3

756

Q8IZD9
SVTRVITVQVANFTL

FCGBP

1306

Q9Y6R7
VSVTRVITVQVANFT

FCGBP

2506

Q9Y6R7
RVSVTRVITVQVANF

FCGBP

3706

Q9Y6R7
VSTNIDICFQVTQTI

CCR9

291

P51686
TFQTVRIFSELNSTE

CC2D1B

686

Q5T0F9
ASTIFQRNSQTDVVE

AGAP7P

86

Q5VUJ5
FSVNSEVSVFEVNIR

MAN1A2

256

O60476
VTFVNFTVTRSSLQS

DYNC1H1

3696

Q14204
STLTISNIVRADFQT

KIRREL3

481

Q8IZU9
REEQFNSTFRVVSVL

IGHG2

171

P01859
STLTFQIVTDSARIQ

CUZD1

121

Q86UP6
QIVTDSARIQRTVFV

CUZD1

126

Q86UP6
VIRTLSTFKNTEISF

FABP7

51

O15540
VRSQGFVTLLFNVVT

B9D1

161

Q9UPM9
VVQSLFSVSSFSQIT

SEC24C

1001

P53992
AASTSQTSVQLIVFV

SLC39A9

166

Q9NUM3
VEATFQRQFVLTLSE

POLR3E

566

Q9NVU0
VQTATFQVFVFESLL

CD244

116

Q9BZW8
EAVTSIQQLFQLSVS

DELE1

231

Q14154
FRSVGTFNIIVTAEN

PKD1

1601

P98161
SFFVAQATVTVQVLA

PKD1

2131

P98161
TDTTVNEIINFVVSV

OR10J3

191

Q5JRS4
VAFSVLVVVFQTQFR

SLC26A9

486

Q7LBE3
QDTSFTTLVERVIQQ

GFPT1

166

Q06210
VRTTATAASNLIEVF

NDUFS1

21

P28331
TVILDFTQVNFIDSV

SLC26A5

641

P58743
RPFLVVIFSTSTQSV

SERPINA4

401

P29622
VNTIVFVDENRRFVS

CDC40

421

O60508
VFTSRVIITAVTENF

PKHD1

1731

P08F94
SVAFQLLTIVFRTQF

SLC26A3

491

P40879
VVFESSVVIQQLCSV

PIGC

51

Q92535
TITNRFEQAFITSLI

PLA2R1

551

Q13018
NAVESLVQLFSTVSV

STK32C

301

Q86UX6
STERFSQNFKVVVVD

ADAM17

86

P78536
FSLVTLFVVVQQQTR

CLEC4F

51

Q8N1N0
IITDVATFQTTQGFI

PIK3R4

1331

Q99570
TQFVNQFTTQTVVLT

VWDE

1251

Q8N2E2
NILFSVETQTTEERT

TTC13

701

Q8NBP0
AVVETVFFLTSRTRA

ZSWIM9

206

Q86XI8
SRQLARVFFESVVLT

TAS1R1

276

Q7RTX1
TQVFRESQSVENLVI

SEMA4G

471

Q9NTN9
REFLSVSRTVQQVIN

TMPRSS7

131

Q7RTY8
RTAVFVTIFNTVNTS

TIMMDC1

141

Q9NPL8
QETLLVIAFVFEVST

TEAD3

406

Q99594
NVVRTIVTETSFTID

TBC1D9

811

Q6ZT07
NVTQVVDFVAATLQR

TANGO6

661

Q9C0B7
VLLTDTNTQFVEQTI

NF1

951

P21359
QILASTEAFSRFETI

STAB1

511

Q9NY15
FQNTFVVSVTTTVCS

USF3

331

Q68DE3
VTFTSFQSVQKITSR

USP38

921

Q8NB14
ANRAISTVEFVTAAV

PLAAT1

136

Q9HDD0
SVQALTEIQEFISFI

PRKDC

3131

P78527
QVSVTFEDVAVTFTQ

ZNF543

6

Q08ER8
QVSLTFEDVAVLFTR

ZNF354A

11

O60765
FQVTTTANKVGRFSV

WNK1

1946

Q9H4A3
TVRVFRFITDNTVEE

SMARCA5

601

O60264
QIFIQVLETFSESAI

ZYG11A

561

Q6WRX3
EFEERVSVSFIRTIQ

MYO5A

1791

Q9Y4I1
FEQVATSSVFQEVTL

NAT9

161

Q9BTE0