Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncAMP-dependent protein kinase activity

PRKACA PRKACB PRKACG

3.96e-067983GO:0004691
GeneOntologyMolecularFunctionserine-type endopeptidase activity

ACR PRSS36 PRSS3P2 BMP1 PROZ TLL1 MST1L KLK13

4.39e-06190988GO:0004252
GeneOntologyMolecularFunctionserine-type peptidase activity

ACR PRSS36 PRSS3P2 BMP1 PROZ TLL1 MST1L KLK13

8.25e-06207988GO:0008236
GeneOntologyMolecularFunctionendopeptidase activity

ADAM21 ACR PRSS36 PRSS3P2 BMP1 CNTNAP5 PROZ TLL1 ADAMTS20 MST1L KLK13

8.47e-064309811GO:0004175
GeneOntologyMolecularFunctioncyclic nucleotide-dependent protein kinase activity

PRKACA PRKACB PRKACG

9.43e-069983GO:0004690
GeneOntologyMolecularFunctionserine hydrolase activity

ACR PRSS36 PRSS3P2 BMP1 PROZ TLL1 MST1L KLK13

9.82e-06212988GO:0017171
GeneOntologyMolecularFunctionAMP-activated protein kinase activity

PRKACA PRKACB PRKACG

1.34e-0510983GO:0004679
GeneOntologyMolecularFunctionpeptidase activity

ADAM21 ACR PRSS36 PRSS3P2 BMP1 CNTNAP5 PROZ TLL1 ADAMTS20 MST1L KLK13 ZRANB1

8.55e-056549812GO:0008233
GeneOntologyMolecularFunctionDNA helicase activity

ERCC2 RTEL1 ZRANB3 RECQL5

2.45e-0462984GO:0003678
GeneOntologyMolecularFunctionhelicase activity

ERCC2 RTEL1 ZNFX1 ZRANB3 RECQL5

1.09e-03158985GO:0004386
GeneOntologyCellularComponentcAMP-dependent protein kinase complex

PRKACA PRKACB PRKACG

1.10e-0510963GO:0005952
Domain-

SUMF2 SUMF1

2.56e-0529523.90.1580.10
DomainFGE-sulfatase

SUMF2 SUMF1

2.56e-052952PF03781
DomainSUMF_dom

SUMF2 SUMF1

2.56e-052952IPR005532
DomainBMP_1/tolloid-like

BMP1 TLL1

7.65e-053952IPR015446
DomainHelicase_C_2

ERCC2 RTEL1

1.53e-044952PF13307
DomainHELICASE_ATP_BIND_2

ERCC2 RTEL1

1.53e-044952PS51193
DomainDEAD_2

ERCC2 RTEL1

1.53e-044952PF06733
DomainDEAD_2

ERCC2 RTEL1

1.53e-044952IPR010614
DomainATP-dep_Helicase_C

ERCC2 RTEL1

1.53e-044952IPR006555
DomainHelicase-like_DEXD_c2

ERCC2 RTEL1

1.53e-044952IPR006554
DomainHelic_SF1/SF2_ATP-bd_DinG/Rad3

ERCC2 RTEL1

1.53e-044952IPR014013
DomainDNA_helicase_DNA-repair_Rad3

ERCC2 RTEL1

1.53e-044952IPR013020
DomainDEXDc2

ERCC2 RTEL1

1.53e-044952SM00488
DomainHELICc2

ERCC2 RTEL1

1.53e-044952SM00491
DomainWSC

PKD1 WSCD2

2.53e-045952SM00321
DomainWSC_carb-bd

PKD1 WSCD2

2.53e-045952IPR002889
DomainWSC

PKD1 WSCD2

2.53e-045952PF01822
DomainWSC

PKD1 WSCD2

2.53e-045952PS51212
DomainPeptidase_S1A

ACR PRSS36 PROZ MST1L KLK13

2.79e-04113955IPR001314
DomainTRYPSIN_DOM

ACR PRSS36 PROZ MST1L KLK13

3.02e-04115955PS50240
DomainTryp_SPc

ACR PRSS36 PROZ MST1L KLK13

3.27e-04117955SM00020
DomainPeptidase_M12A

BMP1 TLL1

3.79e-046952IPR001506
DomainAstacin

BMP1 TLL1

3.79e-046952PF01400
DomainTrypsin

ACR PRSS36 PROZ MST1L KLK13

3.82e-04121955PF00089
DomainTrypsin_dom

ACR PRSS36 PROZ MST1L KLK13

3.82e-04121955IPR001254
DomainPeptidase_S1_PA

ACR PRSS36 PROZ MST1L KLK13

4.12e-04123955IPR009003
DomainDNA/RNA_helicase_DEAH_CS

ERCC2 RTEL1 RECQL5

7.42e-0435953IPR002464
DomainMetalloPept_cat_dom

ADAM21 BMP1 TLL1 ADAMTS20

7.75e-0481954IPR024079
Domain-

ADAM21 BMP1 TLL1 ADAMTS20

7.75e-04819543.40.390.10
DomainDEAH_ATP_HELICASE

ERCC2 RTEL1 RECQL5

9.45e-0438953PS00690
DomainEGF_3

ADAM21 LDLR BMP1 CNTNAP5 PROZ TLL1

1.27e-03235956PS50026
DomainZINC_PROTEASE

ADAM21 BMP1 TLL1 ADAMTS20

1.57e-0398954PS00142
DomainQuinoprot_gluc/sorb_DH

EML2 FBXW5

1.63e-0312952IPR011041
DomainEGF-like_dom

ADAM21 LDLR BMP1 CNTNAP5 PROZ TLL1

1.71e-03249956IPR000742
DomainEGF_1

ADAM21 LDLR BMP1 CNTNAP5 PROZ TLL1

1.93e-03255956PS00022
DomainEGF-type_Asp/Asn_hydroxyl_site

LDLR BMP1 PROZ TLL1

2.10e-03106954IPR000152
DomainEGF_2

ADAM21 LDLR BMP1 CNTNAP5 PROZ TLL1

2.34e-03265956PS01186
DomainAGC-kinase_C

PRKACA PRKACB PRKACG

2.91e-0356953IPR000961
DomainAGC_KINASE_CTER

PRKACA PRKACB PRKACG

2.91e-0356953PS51285
DomainS_TK_X

PRKACA PRKACB PRKACG

2.91e-0356953SM00133
DomainEGF_CA

LDLR BMP1 PROZ TLL1

3.49e-03122954SM00179
DomainEGF-like_Ca-bd_dom

LDLR BMP1 PROZ TLL1

3.70e-03124954IPR001881
DomainRUN

DENND5B RUNDC3A

3.71e-0318952SM00593
DomainRUN

DENND5B RUNDC3A

4.14e-0319952PS50826
DomainRUN

DENND5B RUNDC3A

4.14e-0319952PF02759
DomainRun_dom

DENND5B RUNDC3A

4.14e-0319952IPR004012
DomainPLAT

DENND5B PKD1

5.05e-0321952PS50095
Domain-

DENND5B PKD1

5.05e-03219522.60.60.20
DomainPLAT

DENND5B PKD1

5.05e-0321952PF01477
DomainPLAT/LH2_dom

DENND5B PKD1

5.05e-0321952IPR001024
PathwayREACTOME_HDL_ASSEMBLY

BMP1 PRKACA PRKACB PRKACG

4.82e-088744M27840
PathwayREACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_KEY_METABOLIC_FACTORS

PRKACA PRKACB PRKACG

1.38e-065743M26988
PathwayREACTOME_PLASMA_LIPOPROTEIN_ASSEMBLY

BMP1 PRKACA PRKACB PRKACG

2.55e-0619744M27841
PathwayKEGG_MEDICUS_REFERENCE_PKA_HOLOENZYME

PRKACA PRKACB PRKACG

4.79e-067743M47896
PathwayREACTOME_HDL_ASSEMBLY

BMP1 PRKACA PRKACB

4.79e-067743MM15560
PathwayREACTOME_ROBO_RECEPTORS_BIND_AKAP5

PRKACA PRKACB PRKACG

1.14e-059743M27877
PathwayKEGG_MEDICUS_REFERENCE_AVP_V2R_PKA_SIGNALING_PATHWAY

PRKACA PRKACB PRKACG

1.62e-0510743M47648
PathwayWP_GPR143_IN_MELANOCYTES_AND_RETINAL_PIGMENT_EPITHELIUM_CELLS

GPR143 PRKACA PRKACB PRKACG

1.73e-0530744M42578
PathwayREACTOME_REGULATION_OF_GLYCOLYSIS_BY_FRUCTOSE_2_6_BISPHOSPHATE_METABOLISM

PRKACA PRKACB PRKACG

2.95e-0512743M27950
PathwayREACTOME_CREB1_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_ADENYLATE_CYCLASE

PRKACA PRKACB PRKACG

2.95e-0512743M27363
PathwayKEGG_MEDICUS_REFERENCE_ADRB3_UCP1_SIGNALING_PATHWAY

PRKACA PRKACB PRKACG SMARCC1

3.24e-0535744M47969
PathwayWP_DOPAMINE_METABOLISM

PRKACA PRKACB PRKACG

3.82e-0513743M39622
PathwayREACTOME_PLASMA_LIPOPROTEIN_ASSEMBLY_REMODELING_AND_CLEARANCE

LDLR BMP1 PRKACA PRKACB PRKACG

4.51e-0575745M27032
PathwayBIOCARTA_GATA3_PATHWAY

GATA3 PRKACB PRKACG

4.85e-0514743M1394
PathwayKEGG_MEDICUS_REFERENCE_EP_NE_ADRB_CAMP_SIGNALING_PATHWAY

PRKACA PRKACB PRKACG

6.04e-0515743M47794
PathwayKEGG_MEDICUS_REFERENCE_PTH_PTH1R_PKA_SIGNALING_PATHWAY

PRKACA PRKACB PRKACG

6.04e-0515743M47504
PathwayPID_REG_GR_PATHWAY

GATA3 PRKACA PRKACB PRKACG SMARCC1

6.93e-0582745M115
PathwayKEGG_MEDICUS_REFERENCE_DRD1_GNAS_AC_PKA_SIGNALING_PATHWAY

PRKACA PRKACB PRKACG

7.40e-0516743M47551
PathwayKEGG_MEDICUS_REFERENCE_LHCGR_GNAS_PKA_SIGNALING_PATHWAY

PRKACA PRKACB PRKACG

7.40e-0516743M47645
PathwayKEGG_MEDICUS_REFERENCE_FSHR_GNAS_PKA_SIGNALING_PATHWAY

PRKACA PRKACB PRKACG

7.40e-0516743M47650
PathwayREACTOME_RAP1_SIGNALLING

PRKACA PRKACB PRKACG

7.40e-0516743M923
PathwayREACTOME_PLASMA_LIPOPROTEIN_ASSEMBLY

BMP1 PRKACA PRKACB

8.96e-0517743MM15561
PathwayREACTOME_PKA_ACTIVATION_IN_GLUCAGON_SIGNALLING

PRKACA PRKACB PRKACG

8.96e-0517743M26995
PathwayKEGG_MEDICUS_REFERENCE_CX3CR1_GNAI_AC_PKA_SIGNALING_PATHWAY

PRKACA PRKACB PRKACG

8.96e-0517743M47544
PathwayREACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB

PRKACA PRKACB PRKACG

1.48e-0420743M759
PathwayREACTOME_CD209_DC_SIGN_SIGNALING

PRKACA PRKACB PRKACG

1.73e-0421743M27485
PathwayREACTOME_GAMMA_CARBOXYLATION_HYPUSINYLATION_HYDROXYLATION_AND_ARYLSULFATASE_ACTIVATION

SUMF2 JMJD4 PROZ SUMF1

2.24e-0457744MM14634
PathwayREACTOME_TRIGLYCERIDE_CATABOLISM

PRKACA PRKACB PRKACG

2.60e-0424743M10064
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_GNAS_TO_CRHR_PKA_ACTH_SIGNALING_PATHWAY

PRKACA PRKACB PRKACG

2.60e-0424743M47520
PathwayREACTOME_DARPP_32_EVENTS

PRKACA PRKACB PRKACG

2.60e-0424743M751
PathwayREACTOME_GAMMA_CARBOXYLATION_HYPUSINYLATION_HYDROXYLATION_AND_ARYLSULFATASE_ACTIVATION

SUMF2 JMJD4 PROZ SUMF1

2.91e-0461744M26993
PathwayREACTOME_PLASMA_LIPOPROTEIN_ASSEMBLY_REMODELING_AND_CLEARANCE

LDLR BMP1 PRKACA PRKACB

3.10e-0462744MM14686
PathwayKEGG_MEDICUS_PATHOGEN_HCMV_UL33_TO_GNAI_AC_PKA_SIGNALING_PATHWAY

PRKACA PRKACB PRKACG

3.31e-0426743M47553
PathwayPID_IL3_PATHWAY

PRKACA PRKACB PRKACG

3.31e-0426743M182
PathwayKEGG_MEDICUS_REFERENCE_CRHR_PKA_ACTH_SIGNALING_PATHWAY

PRKACA PRKACB PRKACG

3.71e-0427743M47518
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_RASD1_TO_CRHR_PKA_ACTH_SIGNALING_PATHWAY

PRKACA PRKACB PRKACG

3.71e-0427743M47519
PathwayREACTOME_GLUCAGON_SIGNALING_IN_METABOLIC_REGULATION

PRKACA PRKACB

4.02e-046742MM14628
PathwayKEGG_MEDICUS_REFERENCE_GHRHR_PKA_GH_SIGNALING_PATHWAY

PRKACA PRKACB PRKACG

4.14e-0428743M47647
PathwayWP_LIPID_METABOLISM_PATHWAY

PRKACA PRKACB PRKACG

4.60e-0429743M39762
PathwayKEGG_MEDICUS_REFERENCE_TSH_TG_SIGNALING_PATHWAY

PRKACA PRKACB PRKACG

4.60e-0429743M47627
PathwayWP_CANNABINOID_RECEPTOR_SIGNALING

PRKACA PRKACB PRKACG

4.60e-0429743M39676
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_GNAS_TO_ACTH_CORTISOL_SIGNALING_PATHWAY

PRKACA PRKACB PRKACG

4.60e-0429743M47515
PathwayKEGG_MEDICUS_VARIANT_CYP11B1_CYP11B2_FUSION_TO_ACTH_CORTISOL_SIGNALING_PATHWAY

PRKACA PRKACB PRKACG

5.62e-0431743M47507
PathwayKEGG_MEDICUS_REFERENCE_ACTH_CORTISOL_SIGNALING_PATHWAY

PRKACA PRKACB PRKACG

6.17e-0432743M47506
PathwayWP_CARDIOMYOCYTE_SIGNALING_CONVERGING_ON_TITIN

PRKACA PRKACB PRKACG

6.77e-0433743M48071
PathwayREACTOME_GLUCAGON_SIGNALING_IN_METABOLIC_REGULATION

PRKACA PRKACB PRKACG

6.77e-0433743M11575
PathwayREACTOME_THE_ACTIVATION_OF_ARYLSULFATASES

SUMF2 SUMF1

7.46e-048742MM14651
PathwayKEGG_PRION_DISEASES

PRKACA PRKACB PRKACG

8.05e-0435743M13036
PathwayPID_GMCSF_PATHWAY

PRKACA PRKACB PRKACG

8.75e-0436743M22
PathwayREACTOME_CA_DEPENDENT_EVENTS

PRKACA PRKACB PRKACG

9.49e-0437743M749
PathwayREACTOME_TRIGLYCERIDE_METABOLISM

PRKACA PRKACB PRKACG

1.03e-0338743M27856
PathwayKEGG_APOPTOSIS

PRKACA PRKACB PRKACG ATM

1.12e-0387744M8492
PathwayREACTOME_RET_SIGNALING

PRKACA PRKACB PRKACG

1.19e-0340743M27746
PathwayWP_COMMON_PATHWAYS_UNDERLYING_DRUG_ADDICTION

PRKACA PRKACB PRKACG

1.28e-0341743M39655
PathwayREACTOME_DAG_AND_IP3_SIGNALING

PRKACA PRKACB PRKACG

1.28e-0341743M512
PathwayREACTOME_GLUCAGON_LIKE_PEPTIDE_1_GLP1_REGULATES_INSULIN_SECRETION

PRKACA PRKACB PRKACG

1.38e-0342743M791
PathwayBIOCARTA_AKAP95_PATHWAY

PRKACB PRKACG

1.45e-0311742M5731
PathwayBIOCARTA_PLCE_PATHWAY

PRKACB PRKACG

1.45e-0311742M5576
PathwayBIOCARTA_CFTR_PATHWAY

PRKACB PRKACG

1.45e-0311742M12399
PathwayBIOCARTA_AGPCR_PATHWAY

PRKACB PRKACG

1.45e-0311742M19829
PathwayBIOCARTA_AKAP13_PATHWAY

PRKACB PRKACG

1.45e-0311742M17668
PathwayWP_HEDGEHOG_SIGNALING_WP4249

PRKACA PRKACB PRKACG

1.47e-0343743M39706
PathwayREACTOME_ADORA2B_MEDIATED_ANTI_INFLAMMATORY_CYTOKINES_PRODUCTION

PRKACA PRKACB PRKACG

1.47e-0343743M29837
PathwayREACTOME_VASOPRESSIN_REGULATES_RENAL_WATER_HOMEOSTASIS_VIA_AQUAPORINS

PRKACA PRKACB PRKACG

1.47e-0343743M933
PathwayWP_VASOPRESSINREGULATED_WATER_REABSORPTION

PRKACA PRKACB PRKACG

1.58e-0344743M42554
PathwayKEGG_VASOPRESSIN_REGULATED_WATER_REABSORPTION

PRKACA PRKACB PRKACG

1.58e-0344743M9011
PathwayREACTOME_GPER1_SIGNALING

PRKACA PRKACB PRKACG

1.68e-0345743M45008
PathwayBIOCARTA_CARM1_PATHWAY

PRKACB PRKACG

1.73e-0312742M7968
PathwayREACTOME_THE_ACTIVATION_OF_ARYLSULFATASES

SUMF2 SUMF1

2.04e-0313742M663
PathwayBIOCARTA_DREAM_PATHWAY

PRKACB PRKACG

2.04e-0313742M18899
PathwayREACTOME_CYTOSOLIC_IRON_SULFUR_CLUSTER_ASSEMBLY

ERCC2 RTEL1

2.04e-0313742M27193
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

VWF EMILIN3 COLGALT2 BMP1 ACAN TLL1

2.32e-03258746MM14572
PathwayBIOCARTA_AKAPCENTROSOME_PATHWAY

PRKACB PRKACG

2.37e-0314742M15347
PathwayBIOCARTA_GATA3_PATHWAY

GATA3 PRKACB

2.37e-0314742MM1402
PathwayWP_THERMOGENESIS

PRKACA PRKACB PRKACG SMARCC1

2.48e-03108744M39746
PathwayKEGG_TASTE_TRANSDUCTION

PRKACA PRKACB PRKACG

2.55e-0352743M5785
PathwayREACTOME_AQUAPORIN_MEDIATED_TRANSPORT

PRKACA PRKACB PRKACG

2.55e-0352743M920
PathwayREACTOME_RAP1_SIGNALLING

PRKACA PRKACB

2.73e-0315742MM15019
PathwayREACTOME_ANCHORING_FIBRIL_FORMATION

BMP1 TLL1

2.73e-0315742M27161
PathwayREACTOME_POST_NMDA_RECEPTOR_ACTIVATION_EVENTS

PRKACA PRKACB

2.73e-0315742MM15103
PathwayREACTOME_G_PROTEIN_MEDIATED_EVENTS

PRKACA PRKACB PRKACG

2.84e-0354743M26911
PathwayKEGG_VIBRIO_CHOLERAE_INFECTION

PRKACA PRKACB PRKACG

2.84e-0354743M17906
PathwayBIOCARTA_CK1_PATHWAY

PRKACB PRKACG

3.11e-0316742M16626
PathwayREACTOME_DARPP_32_EVENTS

PRKACA PRKACB

3.11e-0316742MM14699
PathwayREACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB

PRKACA PRKACB

3.11e-0316742MM14492
PathwayBIOCARTA_SHH_PATHWAY

PRKACB PRKACG

3.11e-0316742M11792
PathwayKEGG_HEDGEHOG_SIGNALING_PATHWAY

PRKACA PRKACB PRKACG

3.15e-0356743M1053
PathwayREACTOME_CD209_DC_SIGN_SIGNALING

PRKACA PRKACB

3.51e-0317742MM15215
PathwayREACTOME_DEGRADATION_OF_GLI1_BY_THE_PROTEASOME

PRKACA PRKACB PRKACG

3.83e-0360743M27470
PathwayREACTOME_CROSSLINKING_OF_COLLAGEN_FIBRILS

BMP1 TLL1

3.94e-0318742M27164
PathwayREACTOME_CROSSLINKING_OF_COLLAGEN_FIBRILS

BMP1 TLL1

3.94e-0318742MM14882
PathwayREACTOME_COLLAGEN_BIOSYNTHESIS_AND_MODIFYING_ENZYMES

COLGALT2 BMP1 TLL1

4.02e-0361743MM14637
Pubmed

Molecular cloning of a tissue-specific protein kinase (C gamma) from human testis--representing a third isoform for the catalytic subunit of cAMP-dependent protein kinase.

PRKACA PRKACB PRKACG

2.24e-0839932342480
Pubmed

The paradoxical increase in cortisol secretion induced by dexamethasone in primary pigmented nodular adrenocortical disease involves a glucocorticoid receptor-mediated effect of dexamethasone on protein kinase A catalytic subunits.

PRKACA PRKACB PRKACG

2.24e-08399319383776
Pubmed

Active cAMP-dependent protein kinase incorporated within highly purified HIV-1 particles is required for viral infectivity and interacts with viral capsid protein.

PRKACA PRKACB PRKACG

2.24e-08399312842892
Pubmed

Protein kinase A-induced phosphorylation of the p65 subunit of nuclear factor-kappaB promotes Schwann cell differentiation into a myelinating phenotype.

PRKACA PRKACB PRKACG

8.93e-08499318385332
Pubmed

HIV-1 Tat binds to SH3 domains: cellular and viral outcome of Tat/Grb2 interaction.

PRKACA PRKACB PRKACG

2.23e-07599321745501
Pubmed

HIV-1 gp120 induces anergy in naive T lymphocytes through CD4-independent protein kinase-A-mediated signaling.

PRKACA PRKACB PRKACG

2.23e-07599312972513
Pubmed

Overexpressing PKIB in prostate cancer promotes its aggressiveness by linking between PKA and Akt pathways.

PRKACA PRKACB PRKACG

2.23e-07599319483721
Pubmed

Effects of [D-Ala1] peptide T-NH2 and HIV envelope glycoprotein gp120 on cyclic AMP dependent protein kinases in normal and psoriatic human fibroblasts.

PRKACA PRKACB PRKACG

2.23e-0759939540970
Pubmed

PKA-mediated stabilization of FoxH1 negatively regulates ERalpha activity.

PRKACA PRKACB PRKACG

2.23e-07599319711044
Pubmed

Architectural DNA-binding properties of the spermatidal transition proteins 1 and 2.

PRKACA PRKACB PRKACG

4.45e-0769939837753
Pubmed

Ser276 phosphorylation of NF-kB p65 by MSK1 controls SCF expression in inflammation.

PRKACA PRKACB PRKACG

4.45e-07699319197368
Pubmed

Dynamic binding of PKA regulatory subunit RI alpha.

PRKACA PRKACB PRKACG

7.77e-07799316407073
Pubmed

Phosphorylation of HIV Nef by cAMP-dependent protein kinase.

PRKACA PRKACB PRKACG

7.77e-07799315629779
Pubmed

CCL3L1 prevents gp120-induced neuron death via the CREB cell signaling pathway.

PRKACA PRKACB PRKACG

1.24e-06899319100722
Pubmed

Transcriptional activation of the NF-kappaB p65 subunit by mitogen- and stress-activated protein kinase-1 (MSK1).

PRKACA PRKACB PRKACG

1.24e-06899312628924
Pubmed

Human immunodeficiency virus proteins induce the inhibitory cAMP/protein kinase A pathway in normal lymphocytes.

PRKACA PRKACB PRKACG

1.86e-0699937688126
Pubmed

HIV-1 Tat-peptide inhibits protein kinase C and protein kinase A through substrate competition.

PRKACA PRKACB PRKACG

2.65e-061099320433920
Pubmed

PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts.

PRKACA PRKACB PRKACG

4.83e-061299310830164
Pubmed

Assignment of the mouse ataxia-telangiectasia gene (Atm) to mouse chromosome 9.

LDLR OAF ATM

4.83e-06129938672141
Pubmed

Phosphorylation of APOBEC3G by protein kinase A regulates its interaction with HIV-1 Vif.

PRKACA PRKACB PRKACG

6.27e-061399318836454
Pubmed

Viral genetic determinants of nonprogressive HIV type 1 subtype C infection in antiretroviral drug-naive children.

PRKACA PRKACB PRKACG

6.27e-061399319895210
Pubmed

The HIV-1 matrix protein p17 activates the transcription factors c-Myc and CREB in human B cells.

PRKACA PRKACB PRKACG

6.27e-061399320402410
Pubmed

Protein kinase A phosphorylation activates Vpr-induced cell cycle arrest during human immunodeficiency virus type 1 infection.

PRKACA PRKACB PRKACG

6.27e-061399320392842
Pubmed

Evidence for a second isoform of the catalytic subunit of cAMP-dependent protein kinase.

PRKACA PRKACB

8.02e-0629923023318
Pubmed

Bone morphogenetic protein 1 cleaves the linker region between ligand-binding repeats 4 and 5 of the LDL receptor and makes the LDL receptor non-functional.

LDLR BMP1

8.02e-06299231600776
Pubmed

RGA protein associates with a TRPV ion channel during biosynthesis and trafficking.

SLC50A1 TRPV2

8.02e-06299214991772
Pubmed

Skeletal muscle expression of bone morphogenetic protein-1 and tolloid-like-1 extracellular proteases in different fiber types and in response to unloading, food deprivation and differentiation.

BMP1 TLL1

8.02e-06299220658214
Pubmed

Investigation of -PRKACA/-PRKACB fusion genes in oncocytic tumors of the pancreatobiliary and other systems.

PRKACA PRKACB

8.02e-06299236152045
Pubmed

PRKACA/PRKACB Fusions in Pancreatobiliary Intraductal Oncocytic Papillary Neoplasms Including Those With Atypical Morphology: An Analysis of 22 Cases Expanding Morphologic Spectrum.

PRKACA PRKACB

8.02e-06299238841868
Pubmed

Bone morphogenetic protein-1 and a mammalian tolloid homologue (mTld) are encoded by alternatively spliced transcripts which are differentially expressed in some tissues.

BMP1 TLL1

8.02e-0629927798260
Pubmed

Molecular and behavioral effects of a null mutation in all PKA C beta isoforms.

PRKACA PRKACB

8.02e-06299212139926
Pubmed

Effect of Reducing Ataxia-Telangiectasia Mutated (ATM) in Experimental Autosomal Dominant Polycystic Kidney Disease.

PKD1 ATM

8.02e-06299233802342
Pubmed

Characterization of genomic clones coding for the C alpha and C beta subunits of mouse cAMP-dependent protein kinase.

PRKACA PRKACB

8.02e-0629922833513
Pubmed

Proteolysis of the low density lipoprotein receptor by bone morphogenetic protein-1 regulates cellular cholesterol uptake.

LDLR BMP1

8.02e-06299231388055
Pubmed

Characterization of a novel gene product (mammalian tolloid-like) with high sequence similarity to mammalian tolloid/bone morphogenetic protein-1.

BMP1 TLL1

8.02e-0629928661043
Pubmed

Global consequences of activation loop phosphorylation on protein kinase A.

PRKACA PRKACB

8.02e-06299219965870
Pubmed

Inactivation of bone morphogenetic protein 1 (Bmp1) and tolloid-like 1 (Tll1) in cells expressing type I collagen leads to dental and periodontal defects in mice.

BMP1 TLL1

8.02e-06299228000152
Pubmed

Characterization of the cAMP-dependent protein kinase catalytic subunit Cgamma expressed and purified from sf9 cells.

PRKACA PRKACG

8.02e-06299215039079
Pubmed

Paralog of the formylglycine-generating enzyme--retention in the endoplasmic reticulum by canonical and noncanonical signals.

SUMF2 SUMF1

8.02e-06299218266766
Pubmed

Protein kinase A translocation and insulin secretion in pancreatic beta-cells: studies with adenylate cyclase toxin from Bordetella pertussis.

PRKACA PRKACB

8.02e-06299212180908
Pubmed

Some mutations in the xeroderma pigmentosum D gene may lead to moderate but significant radiosensitivity associated with a delayed radiation-induced ATM nuclear localization.

ERCC2 ATM

8.02e-06299231738647
Pubmed

Proteolysis of the low-density lipoprotein receptor in hepatocytes is mediated by BMP1 but not by other astacin proteases.

LDLR BMP1

8.02e-06299237235726
Pubmed

The multiple sulfatase deficiency gene encodes an essential and limiting factor for the activity of sulfatases.

SUMF2 SUMF1

8.02e-06299212757706
Pubmed

Multiple sulfatase deficiency is caused by mutations in the gene encoding the human C(alpha)-formylglycine generating enzyme.

SUMF2 SUMF1

8.02e-06299212757705
Pubmed

Recurrent Rearrangements in PRKACA and PRKACB in Intraductal Oncocytic Papillary Neoplasms of the Pancreas and Bile Duct.

PRKACA PRKACB

8.02e-06299231678302
Pubmed

Proteinase bone morphogenetic protein 1, but not tolloid-like 1, plays a dominant role in maintaining periodontal homeostasis.

BMP1 TLL1

8.02e-06299233169406
Pubmed

Systems-level identification of PKA-dependent signaling in epithelial cells.

PRKACA PRKACB

8.02e-06299228973931
Pubmed

Kidney Cyst Lining Epithelial Cells Are Resistant to Low-Dose Cisplatin-Induced DNA Damage in a Preclinical Model of Autosomal Dominant Polycystic Kidney Disease.

PKD1 ATM

8.02e-06299236293397
Pubmed

Gene Rearrangement and Expression of PRKACA and PRKACB Govern Morphobiology of Pancreatobiliary Oncocytic Neoplasms.

PRKACA PRKACB

8.02e-06299237871652
Pubmed

Localized reduction of atherosclerosis in von Willebrand factor-deficient mice.

VWF LDLR

8.02e-06299211520791
Pubmed

cAMP-dependent protein kinase: framework for a diverse family of regulatory enzymes.

PRKACA PRKACB PRKACG

9.93e-06159932165385
Pubmed

Multiple APOBEC3 restriction factors for HIV-1 and one Vif to rule them all.

PRKACA PRKACB PRKACG

1.48e-051799324189052
Pubmed

Structural basis for the substrate specificity of bone morphogenetic protein 1/tolloid-like metalloproteases.

BMP1 TLL1

2.40e-05399218824173
Pubmed

Use of Bmp1/Tll1 doubly homozygous null mice and proteomics to identify and validate in vivo substrates of bone morphogenetic protein 1/tolloid-like metalloproteinases.

BMP1 TLL1

2.40e-05399212808086
Pubmed

BMP1 and TLL1 Are Required for Maintaining Periodontal Homeostasis.

BMP1 TLL1

2.40e-05399228068493
Pubmed

Precise Spatiotemporal Control of Nodal Na+ Channel Clustering by Bone Morphogenetic Protein-1/Tolloid-like Proteinases.

BMP1 TLL1

2.40e-05399232209430
Pubmed

A genetic test of the effects of mutations in PKA on mossy fiber LTP and its relation to spatial and contextual learning.

PRKACA PRKACB

2.40e-0539928548807
Pubmed

Monogenic and polygenic determinants of sarcoma risk: an international genetic study.

ERCC2 ATM

2.40e-05399227498913
Pubmed

Bone morphogenetic protein-1 processes probiglycan.

BMP1 TLL1

2.40e-05399210896944
Pubmed

Induced ablation of Bmp1 and Tll1 produces osteogenesis imperfecta in mice.

BMP1 TLL1

2.40e-05399224419319
Pubmed

RECQL5 and BLM exhibit divergent functions in cells defective for the Fanconi anemia pathway.

FANCB RECQL5

2.40e-05399225520194
Pubmed

Essential Roles of Bone Morphogenetic Protein-1 and Mammalian Tolloid-like 1 in Postnatal Root Dentin Formation.

BMP1 TLL1

2.40e-05399227847137
Pubmed

Secreted Frizzled-related protein 2 is a procollagen C proteinase enhancer with a role in fibrosis associated with myocardial infarction.

BMP1 TLL1

2.40e-05399219079247
Pubmed

Involvement of the catalytic subunit of protein kinase A and of HA95 in pre-mRNA splicing.

PRKACA PRKACB

2.40e-05399217594903
Pubmed

Epidermal growth factor receptor levels are reduced in mice with targeted disruption of the protein kinase A catalytic subunit.

PRKACA PRKACB

2.40e-05399218380891
Pubmed

Structural and functional evidence for a substrate exclusion mechanism in mammalian tolloid like-1 (TLL-1) proteinase.

BMP1 TLL1

2.40e-05399220043912
Pubmed

Mammalian tolloid-like 1 binds procollagen C-proteinase enhancer protein 1 and differs from bone morphogenetic protein 1 in the functional roles of homologous protein domains.

BMP1 TLL1

2.40e-05399216507574
Pubmed

Müllerian inhibiting substance blocks the protein kinase A-induced expression of cytochrome p450 17alpha-hydroxylase/C(17-20) lyase mRNA in a mouse Leydig cell line independent of cAMP responsive element binding protein phosphorylation.

CYP17A1 PRKACA

2.40e-05399212193547
Pubmed

The human immunodeficiency virus coat protein gp120 promotes forward trafficking and surface clustering of NMDA receptors in membrane microdomains.

PRKACA PRKACB PRKACG

2.87e-052199322114277
Pubmed

Human immunodeficiency virus Tat protein induces interleukin 6 mRNA expression in human brain endothelial cells via protein kinase C- and cAMP-dependent protein kinase pathways.

PRKACA PRKACB PRKACG

2.87e-05219939671211
Pubmed

The Nef protein of human immunodeficiency virus type 1 enhances serine phosphorylation of the viral matrix.

PRKACA PRKACB PRKACG

3.31e-05229939151826
Pubmed

Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.

ZNFX1 DSCAML1 CEMIP TBC1D4 CARNS1

3.65e-0513099512421765
Pubmed

Association of DNA repair and steroid metabolism gene polymorphisms with clinical late toxicity in patients treated with conformal radiotherapy for prostate cancer.

ERCC2 CYP17A1 ATM

3.80e-052399316638864
Pubmed

HIV-1 tat molecular diversity and induction of TNF-alpha: implications for HIV-induced neurological disease.

PRKACA PRKACB PRKACG

3.80e-05239939730685
Pubmed

The Tat protein of HIV-1 induces tumor necrosis factor-alpha production. Implications for HIV-1-associated neurological diseases.

PRKACA PRKACB PRKACG

3.80e-05239939278385
Pubmed

Recapitulation of four hypertension susceptibility genes (CSK, CYP17A1, MTHFR, and FGF5) in East Asians.

CYP17A1 FGF5

4.79e-05499222959498
Pubmed

The mammalian Tolloid-like 1 gene, Tll1, is necessary for normal septation and positioning of the heart.

BMP1 TLL1

4.79e-05499210331975
Pubmed

Heterozygous mutation of ataxia-telangiectasia mutated gene aggravates hypercholesterolemia in apoE-deficient mice.

LDLR ATM

4.79e-05499215863839
Pubmed

Rap1GAP2 is a new GTPase-activating protein of Rap1 expressed in human platelets.

PRKACA PRKACG

4.79e-05499215632203
Pubmed

GPCR signaling inhibits mTORC1 via PKA phosphorylation of Raptor.

PRKACA PRKACB

4.79e-05499231112131
Pubmed

Discrete control of TRPV4 channel function in the distal nephron by protein kinases A and C.

PRKACA PRKACB

4.79e-05499223709216
Pubmed

Germline and Mosaic Variants in PRKACA and PRKACB Cause a Multiple Congenital Malformation Syndrome.

PRKACA PRKACB

4.79e-05499233058759
Pubmed

Differential role of PKA catalytic subunits in mediating phenotypes caused by knockout of the Carney complex gene Prkar1a.

PRKACA PRKACB

4.79e-05499221852354
Pubmed

BMP1-like proteinases are essential to the structure and wound healing of skin.

BMP1 TLL1

4.79e-05499227363389
Pubmed

Regulation of glycoprotein Ib-IX-von Willebrand factor interaction by cAMP-dependent protein kinase-mediated phosphorylation at Ser 166 of glycoprotein Ib(beta).

VWF PRKACG

4.79e-05499212361948
Pubmed

Cloning of a mouse protein kinase A catalytic subunit pseudogene and chromosomal mapping of C subunit isoforms.

PRKACA PRKACB

4.79e-0549927873880
Pubmed

Glucose-dependent regulation of AMP-activated protein kinase in MIN6 beta cells is not affected by the protein kinase A pathway.

PRKACA PRKACB

4.79e-05499223116618
Pubmed

Identification and characterization of four novel phosphorylation sites (Ser31, Ser325, Thr336 and Thr366) on LKB1/STK11, the protein kinase mutated in Peutz-Jeghers cancer syndrome.

PRKACA ATM

4.79e-05499211853558
Pubmed

Role of caveolin-1 in the modulation of lipolysis and lipid droplet formation.

PRKACA PRKACB

4.79e-05499215111495
Pubmed

A humble hexose monophosphate pathway metabolite regulates short- and long-term control of lipogenesis.

PRKACA PRKACG

4.79e-05499212721358
Pubmed

Role of phosphorylation in the nuclear biology of HIV-1.

PRKACA PRKACB PRKACG

6.23e-052799321651489
Pubmed

BMP-binding protein twisted gastrulation is required in mammary gland epithelium for normal ductal elongation and myoepithelial compartmentalization.

NOG GATA3 BMP1

6.96e-052899323103586
Pubmed

Developmentally acquired PKA localisation in mouse oocytes and embryos.

PRKACA PRKACB

7.98e-05599218367160
Pubmed

Involvement of protein kinase A in patterning of the mouse somatosensory cortex.

PRKACA PRKACB

7.98e-05599216707791
Pubmed

PCOLCE2 encodes a functional procollagen C-proteinase enhancer (PCPE2) that is a collagen-binding protein differing in distribution of expression and post-translational modification from the previously described PCPE1.

BMP1 TLL1

7.98e-05599212393877
Pubmed

ATM-dependent suppression of stress signaling reduces vascular disease in metabolic syndrome.

LDLR ATM

7.98e-05599217084711
Pubmed

Protein kinases A and C in post-mortem prefrontal cortex from persons with major depression and normal controls.

PRKACA PRKACB

7.98e-05599219573263
Pubmed

Deficiency of ataxia telangiectasia mutated kinase modulates cardiac remodeling following myocardial infarction: involvement in fibrosis and apoptosis.

TIMP4 ATM

7.98e-05599224358288
Pubmed

VPS34 K29/K48 branched ubiquitination governed by UBE3C and TRABID regulates autophagy, proteostasis and liver metabolism.

UBE3C ZRANB1

7.98e-05599233637724
Pubmed

PKACs attenuate innate antiviral response by phosphorylating VISA and priming it for MARCH5-mediated degradation.

PRKACA PRKACB

7.98e-05599228934360
GeneFamilyBone morphogenetic proteins|Astacins

BMP1 TLL1

1.78e-046632894
GeneFamilyDNA helicases

ERCC2 RTEL1

1.57e-03176321167
GeneFamilyZinc fingers RANBP2-type |RNA binding motif containing

ZRANB3 ZRANB1

2.40e-032163289
CoexpressionMIKKELSEN_MCV6_HCP_WITH_H3K27ME3

NOG EMILIN3 SLC32A1 ABCG4 OAF ACAN SKOR1 WSCD2 FGF5 ALDH1A3

6.35e-064389910M1954
CoexpressionMIKKELSEN_MCV6_HCP_WITH_H3K27ME3

NOG EMILIN3 SLC32A1 ABCG4 OAF ACAN SKOR1 WSCD2 FGF5 ALDH1A3

6.60e-064409910MM832
CoexpressionGSE29949_MICROGLIA_BRAIN_VS_CD8_NEG_DC_SPLEEN_DN

CYP17A1 GPR143 EML2 CEMIP FAM53B ATM DNAH9

1.04e-05198997M8400
ToppCelldroplet-Thymus-nan-21m-Lymphocytic-Double_negative_thymocyte,_DN3_(Cd8-,_Cd4-),_some_express_pre_TCR_alpha|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LDLR TBC1D4 POMGNT2 OAF NYNRIN OSBPL1A DNTT

1.27e-07174997a9f34d1237f335d27c5560ff514368f4709f9144
ToppCellEndothelial-A-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

JCAD GPR4 VWF ACR ADAD2 TLL1 TEX28

2.65e-07194997abea887dd472c1a0d572e690bc8914c1b94712ad
ToppCellfacs-Marrow-Granulocytes-18m-Lymphocytic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DENND5B RTEL1 RGR FBXW5 FAM53B UBE3C

1.75e-061639967a04192710f55acf5a4681d5f09942358fdb02ff
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Tpbg|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NOG CEMIP SLC32A1 TBC1D4 ACAN TLL1

1.81e-06164996f0499e6c1b17c4df72b18b294e3b53ef723da2ac
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Tpbg|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NOG CEMIP SLC32A1 TBC1D4 ACAN TLL1

1.94e-06166996b4241f8d2a0aa910dbb0d0d5d3631a9b73453fe9
ToppCelldroplet-Thymus-nan-21m-Lymphocytic-DN3_thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBC1D4 POMGNT2 OAF NYNRIN OSBPL1A DNTT

2.73e-06176996d43d9e86c4d4fa1e88fbf2b899ac7143717aac90
ToppCellfacs-Lung-nan-3m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD GPR4 VWF ACR MCTP1 TLL1

3.42e-0618399612e876d6205af8aad74265c668b5e95b9e7487f3
ToppCell5'-Adult-LymphNode-Endothelial-blood_vessel_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

JCAD GPR4 VWF MCTP1 TIMP4 TLL1

4.24e-06190996141266bf411ea675fbf889b20c1b08673c45ff95
ToppCellNS-critical-d_0-4-Epithelial-Basal|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PDGFRL ETFBKMT GATA3 LEMD1 PRSS36 ZRANB3

4.64e-061939961affb4c2e21712bde0d36ab736411fe36642cc6d
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Perivascular_fibroblast|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

JCAD PDGFRL CEMIP OAF NYNRIN ALDH1A3

5.53e-06199996dfc5c7a4a093baa7158dd8d4d29a870d9c469a3f
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Perivascular_fibroblast-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

JCAD PDGFRL CEMIP OAF NYNRIN ALDH1A3

5.53e-06199996c1760581c34b81d1d92c67500a1c8944e9cc6dad
ToppCell10x5'-lymph-node_spleen-Hematopoietic_progenitors-Progenitor|lymph-node_spleen / Manually curated celltypes from each tissue

JCAD CEMIP SLC32A1 NYNRIN DNTT

3.38e-051659957b992843bd8ef92a7a76b1d681fa84efde6f5bdd
ToppCellCerebellum-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Lrg1_(Lrg1)--|Cerebellum / BrainAtlas - Mouse McCarroll V32

RASGRP4 VWF FANCB KCNJ14

3.55e-05839943aa95bf2d8ac37e648037faf3d54ebb243a4fde1
ToppCellCerebellum-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Lrg1_(Lrg1)-|Cerebellum / BrainAtlas - Mouse McCarroll V32

RASGRP4 VWF FANCB KCNJ14

3.55e-058399470804dd63221dd5ed26068ec1b50f11875abbc50
ToppCellCerebellum-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Lrg1_(Lrg1)|Cerebellum / BrainAtlas - Mouse McCarroll V32

RASGRP4 VWF FANCB KCNJ14

3.55e-0583994c1818411438f53aec76afead5c8caab701b95d39
ToppCellCerebellum-Endothelial-ENDOTHELIAL_STALK-Flt1_2|Cerebellum / BrainAtlas - Mouse McCarroll V32

RASGRP4 VWF FANCB KCNJ14

3.55e-05839941e7af8aaa20b4c2a77cf2f330113db0faa9d483c
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NOG CEMIP SLC32A1 ACAN TLL1

3.68e-051689952572a3dd4f3f619bd26a3cd6e60de43821d8bb64
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RASGRP4 ACR GATA3 ZNF483 FGF5

3.90e-0517099555fe16d98ea284d05fb899888e4569c685644c7b
ToppCellFrontal_cortex-Macroglia-POLYDENDROCYTE-P2-Tnr-Polydendrocyte.Tnr.Bmp4-Gpr17_(Bmp4)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

GPR143 TIMP4 ACAN KLK13

4.08e-0586994eb2b9e98ff97371f497ee1709848a2caaa46ed3d
ToppCellFrontal_cortex-Macroglia-POLYDENDROCYTE-P2-Tnr-Polydendrocyte.Tnr.Bmp4-Gpr17_(Bmp4)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

GPR143 TIMP4 ACAN KLK13

4.08e-058699402ea5219e2faded2b50b96d41861e4f8a558e4e3
ToppCellBronchial_Biopsy-Immune-Mast_cells|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

JCAD RASGRP4 FANCB SV2A WSCD2

4.12e-05172995c477008444d2d71071177807870d7455e90c2fad
ToppCellControl-Endothelial_cells-Systemic_venous_endothelial_cells|Control / group, cell type (main and fine annotations)

GPR4 VWF ACR MCTP1 TLL1

4.12e-05172995c55dce1ed3ed7312394b4e050e1de852a994e130
ToppCelldroplet-Thymus-nan-18m-Lymphocytic-DN3_thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LDLR POMGNT2 OAF OSBPL1A DNTT

4.24e-051739955d7c53c6d1cdd385e44b79b82faec901747d1736
ToppCelldroplet-Thymus-nan-3m-Lymphocytic-DN3_thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LDLR POMGNT2 OAF OSBPL1A DNTT

4.35e-05174995b2fc2a756f8e373ad903bd416d9de703d945fa1c
ToppCelldroplet-Thymus-nan-18m-Lymphocytic-Double_negative_thymocyte,_DN3_(Cd8-,_Cd4-),_some_express_pre_TCR_alpha|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LDLR POMGNT2 OAF OSBPL1A DNTT

4.35e-051749959eab43885496b8586f8ec5b4bcb1fd5b209218e5
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GPR4 VWF ACR GATA3 FGF5

4.60e-0517699577516048aefbe1f48e825052756df0c310c1c486
ToppCellfacs-Lung-EPCAM-18m-Endothelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAM21 ACR GATA3 FANCB ITPRIP

4.72e-051779952433924dcb085ebbe2545d476ebd7ee68e6092fb
ToppCell5'-Adult-LymphNode-Endothelial-blood_vessel_EC-arterial_capillary|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

JCAD GPR4 VWF MCTP1 TIMP4

4.85e-05178995360d7a987f91d6d721487a921824057ec31a7332
ToppCellT_cells-TFH-like_cells|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis

PLPP5 VSIG10 TBC1D4 MCTP1 FAM53B

4.85e-05178995e2ae43e5ec31de6197f2cbd6089f944adbf0a163
ToppCellmetastatic_Brain-Endothelial_cells-Lymphatic_ECs|metastatic_Brain / Location, Cell class and cell subclass

VWF OAF TLL1 KCNJ14 ALDH1A3

4.98e-0517999556fe381ffbaba3a4f2f587a3e367b0d11fbd4a2a
ToppCellMesenchymal_cells-Chondrocytes|Mesenchymal_cells / Lineage and Cell class

NOG COLGALT2 CEMIP ACAN WSCD2

5.12e-051809956e399368430ef3afa9ce1ef0ed90f614ccef9987
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_vein-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

JCAD VWF MCTP1 TIMP4 TLL1

5.53e-05183995c1297d8eddfc7132e84ceef14f01b6281f9d0f6a
ToppCellMesenchymal_cells-Chondrocytes|World / Lineage and Cell class

NOG COLGALT2 CEMIP ACAN WSCD2

5.68e-051849951e03f9f08de5ad4d45388a95afad9f23ff0d0e28
ToppCell367C-Lymphocytic-NK_cells-NK_cell_A|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

LRRC43 LYPD5 ITPRIP ATM KIR3DL2

5.82e-0518599525781cf68e693e97dc1885e2879ab24fa946b51e
ToppCell5'-Adult-Appendix-Endothelial-blood_vessel_EC-arterial_capillary|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

JCAD GPR4 VWF ACR MCTP1

6.29e-05188995a11b12f1857953bcdbfb5f25e127f2350c39567d
ToppCell3'-GW_trimst-1-LargeIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

JCAD GPR4 VWF SLC32A1 TBC1D4

6.44e-05189995b5fa3a619e3b554a1a45a551c9b6369075fe5615
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

JCAD GPR4 VWF RTEL1 GPR143

6.61e-0519099506bfb62b94b0faf467ef93d5bc5d08924c770098
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

JCAD VWF MCTP1 TLL1 ITPRIP

6.94e-0519299528eb3a5728e8901bcb5ba12f6b009f41b065fa37
ToppCellfacs-Heart-LA-3m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DENND5B JCAD GPR4 VWF TIMP4

7.29e-0519499533cc4f1d716cb71d54cdedbe9bbdc0d7b17c4777
ToppCellproximal-3-Endothelial-Artery|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

JCAD GPR4 VWF GATA3 TLL1

8.03e-05198995946f72b594d22ae7b8e4c22483814c284cb43eea
ToppCellproximal-Endothelial-Artery|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

JCAD GPR4 VWF GATA3 TLL1

8.03e-051989950e5572298676b6c2a2b1a77967574020b664aebd
ToppCell5'-Adult-Appendix-Endothelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

JCAD GPR4 VWF MCTP1 ITPRIP

8.03e-0519899590e85fe7a0ab376a41666dfff6c0e95b7f1c9475
ToppCellproximal-Endothelial-Artery-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

JCAD GPR4 VWF GATA3 TLL1

8.03e-05198995a56b80bdc824e4cc60366f273fb616cd0efec456
ToppCell343B-Fibroblasts-Fibroblast-F|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

PLPP5 PDGFRL OAF SLC50A1 ALDH1A3

8.22e-0519999508c7e631b2e203dd7dcb75a7f9377d292bc5a0fd
ToppCell343B-Fibroblasts-Fibroblast-F-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

PLPP5 PDGFRL OAF SLC50A1 ALDH1A3

8.22e-051999954338bf6cafc26c5d6497955d91914f84bacfacfa
ToppCell5'-Adult-SmallIntestine-Endothelial-blood_vessel_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

JCAD GPR4 VWF MCTP1 TLL1

8.41e-05200995cd3c638961144a2fc91c437a173cc37c7452fa74
ToppCell5'-Adult-SmallIntestine-Endothelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

JCAD GPR4 VWF MCTP1 TLL1

8.41e-052009952554b77edfe3d378296b0b25625caacbfb1c0e76
Diseasefemale breast cancer (is_implicated_in)

RTEL1 ATM

2.90e-048962DOID:0050671 (is_implicated_in)
DiseaseHypermetropia, Myopia

NOG DSCAML1 CNTNAP5 SUMF1 FGF5

3.90e-04189965HP_0000540, HP_0000545
Diseasealcohol use disorder (implicated_via_orthology)

SLC32A1 PRKACA PRKACB PRKACG SMARCC1

4.50e-04195965DOID:1574 (implicated_via_orthology)
Diseasesenile cataract (is_implicated_in)

ERCC2 ATM

5.65e-0411962DOID:9669 (is_implicated_in)
Diseaselow density lipoprotein cholesterol measurement, phospholipid measurement

ADAM21 LDLR NYNRIN LYPD5

6.48e-04120964EFO_0004611, EFO_0004639
Diseasesexual dimorphism measurement

NOG DLGAP4 COLGALT2 LRRC43 LDLR ACAN NYNRIN PKD1 FAM53B CARNS1 SLC22A20P

9.38e-0411069611EFO_0021796
Diseasefree cholesterol measurement, low density lipoprotein cholesterol measurement

ADAM21 LDLR NYNRIN LYPD5

1.06e-03137964EFO_0004611, EFO_0008591
DiseaseNeoplasm of uncertain or unknown behavior of bladder

ERCC2 ATM

1.07e-0315962C0496930
DiseaseBenign neoplasm of bladder

ERCC2 ATM

1.07e-0315962C0154017
DiseaseCarcinoma in situ of bladder

ERCC2 ATM

1.07e-0315962C0154091
DiseaseCarcinoma of bladder

ERCC2 ATM

1.55e-0318962C0699885
DiseaseNon-alcoholic Fatty Liver Disease

CYP17A1 LDLR PRKACA

1.56e-0370963C0400966
DiseaseNonalcoholic Steatohepatitis

CYP17A1 LDLR PRKACA

1.56e-0370963C3241937
DiseaseAbnormality of refraction

JCAD NOG RGR DSCAML1 CNTNAP5 TLL1 SUMF1 ADAMTS20

1.60e-03673968HP_0000539
Diseaseneck circumference

NOG ADAMTS20

1.73e-0319962EFO_0011043
Diseasecortisol measurement

LDLR CNTNAP5

1.92e-0320962EFO_0005843
Diseaseosteoarthritis, hip, osteoarthritis, knee, total joint arthroplasty

NOG COLGALT2

2.11e-0321962EFO_0004616, EFO_0010726, EFO_1000786
Diseaseinfant body height

ZNFX1 ACAN

2.53e-0323962EFO_0006785
DiseaseIntrahepatic Cholangiocarcinoma

PRKACA PRKACB

2.76e-0324962C0345905
DiseaseExtrahepatic Cholangiocarcinoma

PRKACA PRKACB

2.76e-0324962C3805278
Diseasehippocampal volume

NOG PDGFRL COLGALT2 DSCAML1 FAM53B

2.90e-03297965EFO_0005035
Diseasecorpus collosum mid-posterior volume measurement

KCNV2 CNTNAP5

2.99e-0325962EFO_0010300
DiseaseCholangiocarcinoma

PRKACA PRKACB

3.24e-0326962C0206698

Protein segments in the cluster

PeptideGeneStartEntry
LSYSVREGPCWRKRG

ABCG4

66

Q9H172
ERSPYWACKGTVAGV

ADAD2

226

Q8NCV1
RGRSAKAPGWLSYSL

ADAM21

51

Q9UKJ8
SWGVGCARAKRPGIY

ACR

261

P10323
GCIRTLRYFAGWADK

ALDH1A3

136

P47895
RARGLKLDGCFSYWD

CARNS1

461

A5YM72
FWRKAPLRGRFCGSK

BMP1

386

P13497
DWIRVGLCYPRGTTF

CEMIP

1076

Q8WUJ3
QPGACRRDGYWFLKL

DLGAP4

796

Q9Y2H0
WLPRYSGIGTKDRCK

ADAMTS20

641

P59510
YRWKISVFSGPPCAD

MSANTD5

126

A0A3B3IT52
DRWASTDCPGYKPFL

RIC1

1321

Q4ADV7
LWCSGRSVPLDRQGY

ITPRIP

226

Q8IWB1
YRCFGSFRALPCVWS

KIR3DL2

291

P43630
RTLYGIVSWGDFPCG

KLK13

226

Q9UKR3
CLDYKPSKGRRWAAR

LEMD1

106

Q68G75
RDLTWYAKGRAPCAG

MMTAG2

46

Q9BU76
RVKGRTWTLCGTPEY

PRKACA

191

P17612
FSVKSLFWRTCGRPA

MCTP1

416

Q6DN14
WCFTLRPGTRVGFCY

MST1L

326

Q2TV78
YGRRKCGWTKSPLFV

JCAD

1146

Q9P266
KVWTPVEKRRCYSGG

FAM53B

136

Q14153
LSRVRNKPYDVFGCW

FBXW5

181

Q969U6
ASPRYKSLRFWGSVG

GHDC

466

Q8N2G8
YRRTWAGCAGFRLPV

RASGRP4

336

Q8TDF6
CNSSVGRKYPWAGLR

MDM1

26

Q8TC05
KALGRRQGWCPYFLA

ERCC2

181

P18074
WTVGLYPGKVREARC

POMGNT2

476

Q8NAT1
KRYEGPLWKSSRFFG

OSBPL1A

236

Q9BXW6
PWRTYRGAKVASLCV

NPBWR2

156

P48146
SRSAIYLGRPWDCGF

GPR4

246

P46093
KCYAGWLADGSLRYP

ACAN

621

P16112
CRSSYLPGELLWGHR

KCNJ14

316

Q9UNX9
RPGSFYGTLFTWKQR

FANCB

696

Q8NB91
WASGARPCIPKSFGY

GBA

36

P04062
HYFLPGSRCRLARWG

PRSS36

436

Q5K4E3
WSPSGRRTGSLYCRV

FGF5

81

P12034
SLLRRWPYGSDGCQA

RGR

76

P47804
TPLWRRDGTGHYLCN

GATA3

271

P23771
REFWKLFTGSACRPS

ATM

521

Q13315
FRYFLRKGCSLGPWN

ASB3

361

Q9Y575
WDQPQGCLTYKGRRS

ATP11AUN

61

Q6ZP68
RVKGRTWTLCGTPEY

PRKACB

191

P22694
RVKGRTWTLCGTPEY

PRKACG

191

P22612
CALTGSPEFTIRWYR

DSCAML1

336

Q8TD84
SWRGAYTRFPCERVL

FNDC10

111

F2Z333
KREPGALGARCWSLY

ATG9A

321

Q7Z3C6
TLAYLFWPKRRCPGA

CYP17A1

11

P05093
YGWTGCSLGFQSPRK

GPR143

311

P51810
AGYSSPRGCLYLKDW

JMJD4

171

Q9H9V9
TAWYSPCVSLGRRKS

LDHD

221

Q86WU2
EITGHTYRFPCGRWL

DENND5B

1016

Q6ZUT9
TYRFPCGRWLGKGID

DENND5B

1021

Q6ZUT9
YRAPVTLVRKGCWTG

LYPD5

66

Q6UWN5
PSCRLKLEWVYGYRG

EML2

51

O95834
CRWGPKCPGTVTYRT

EMILIN3

86

Q9NT22
WATCKSYRSPGRLTV

DNAH9

346

Q9NYC9
CFWTYRTRVLIGDPG

ETFBKMT

206

Q8IXQ9
RGLYSNFWCGITPKG

COLGALT2

196

Q8IYK4
GCKDGWVYNRSVFPS

SLC22A20P

106

A6NK97
NSEAAWRIGPLRCYG

CNTNAP5

771

Q8WYK1
REFPCGAGSWNKSRF

LRRC43

41

Q8N309
LFSAVGRGRPASYLW

PKD1

1486

P98161
PCLTSSGAYWEFKRA

NYNRIN

1711

Q9P2P1
SRFWPRYVKVGSCFS

NOG

166

Q13253
SGRSPRYALWFCVGE

IRF3

336

Q14653
RGFWDYIRLACSKVP

RUNDC3A

91

Q59EK9
ARKRGKVLSYWCFSP

RTEL1

446

Q9NZ71
ECAWGSRGSFIPARY

SKOR1

186

P84550
DARAYCAWRGKRLPT

SUMF2

151

Q8NBJ7
WGYGCAQKRRPGVYT

PRSS3P2

216

Q8NHM4
DGYWRKSPLLGRFCG

TLL1

411

O43897
LCPYERRAFALLGWT

DNTT

436

P04053
GYWGVRLKYTPRCCR

KCNV2

186

Q8TDN2
VVTDEFWRRYKGGSP

PROZ

76

P22891
FWRRYKGGSPCISQP

PROZ

81

P22891
PSRADTGSLGRYWGK

SOWAHD

31

A6NJG2
CKGSRIGWSYPAYLD

PDGFRL

96

Q15198
YRRKDGGPATKFWES

SMARCC1

31

Q92922
GKPCVCRYGLSLAWY

OAF

211

Q86UD1
WEYSCRGGLHNRLFP

SUMF1

231

Q8NBK3
VWGNFLSCFGPEYRR

SV2A

431

Q7L0J3
RLGYKIWCGTTSRGY

PGBD2

291

Q6P3X8
GRDGKPSWCRLYYSR

RECQL5

351

O94762
RYGACSEPLAGKWFS

TSSK4

116

Q6SA08
LWDYSRGRCLKTYTG

WDR5B

236

Q86VZ2
WRPDTGFFAYTCGRL

WDR90

1126

Q96KV7
RGEYFWEKRVTGCPP

VWF

2681

P04275
KPYKCEDRGRSFGWS

ZNF721

711

Q8TF20
TSASWCLYGFRLRDP

SLC50A1

171

Q9BRV3
PQGRGKSWRFCAFLS

PLPP5

176

Q8NEB5
RKFTEWCYGPVRVSL

TRPV2

326

Q9Y5S1
VDGTCSWYRGHLPLR

TIMP4

201

Q99727
PSDKRFRLWYVGGSC

TBC1D4

31

O60343
VSAIGYPRGHWFKCR

ZNFX1

1836

Q9P2E3
YSPVFCWKVGNTSRG

VSIG10

436

Q8N0Z9
RWFCYSEVAGPRKAL

ZNF483

56

Q8TF39
CYSGDGRLKSWGLTL

SLC32A1

421

Q9H598
WVPSRCRLYSKDSGP

TEX28

391

O15482
EASSIARRYGPWFKG

WSCD2

81

Q2TBF2
FCWKSPIALGYTRGH

ZRANB1

571

Q9UGI0
SRCSRKSGGAPWLFY

UBE3C

306

Q15386
RYFGKRPQWDCRGAS

ZRANB3

226

Q5FWF4
GSDEWPQRCRGLYVF

LDLR

176

P01130