Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyCellularComponentexocytic vesicle

SYN3 WFS1 UNC13D SLC6A9 OTOF SCAMP5 CLN3 SLC22A2 STON2 SYN1 SYN2

8.70e-0632013711GO:0070382
GeneOntologyCellularComponentlysosome

ABCA3 GALC MAN2B2 WWOX UNC13D LAMP2 FYCO1 NAPRT CLN3 LRP1 CPNE1 CTBS USP4 TRPV3 DEPDC5 ENPEP AP3D1

2.33e-0581113717GO:0005764
GeneOntologyCellularComponentlytic vacuole

ABCA3 GALC MAN2B2 WWOX UNC13D LAMP2 FYCO1 NAPRT CLN3 LRP1 CPNE1 CTBS USP4 TRPV3 DEPDC5 ENPEP AP3D1

2.33e-0581113717GO:0000323
GeneOntologyCellularComponentexocytic vesicle membrane

SYN3 WFS1 SLC6A9 OTOF SCAMP5 SLC22A2 SYN1 SYN2

2.41e-051791378GO:0099501
GeneOntologyCellularComponentsynaptic vesicle membrane

SYN3 WFS1 SLC6A9 OTOF SCAMP5 SLC22A2 SYN1 SYN2

2.41e-051791378GO:0030672
GeneOntologyCellularComponentsynaptic vesicle

SYN3 WFS1 SLC6A9 OTOF SCAMP5 CLN3 SLC22A2 STON2 SYN1 SYN2

2.94e-0530013710GO:0008021
GeneOntologyCellularComponentvacuole

ABCA3 GALC MAN2B2 WWOX GRAMD1A UNC13D LAMP2 FYCO1 NAPRT CLN3 LRP1 CPNE1 CTBS USP4 TRPV3 DEPDC5 ENPEP AP3D1

2.97e-0591313718GO:0005773
GeneOntologyCellularComponenttransport vesicle

SYN3 WFS1 COPB2 UNC13D SLC6A9 OTOF SCAMP5 CLN3 SLC22A2 STON2 SYN1 SYN2 ECE2

3.80e-0551913713GO:0030133
GeneOntologyCellularComponenttransport vesicle membrane

SYN3 WFS1 SLC6A9 OTOF SCAMP5 SLC22A2 SYN1 SYN2 ECE2

1.38e-042931379GO:0030658
GeneOntologyCellularComponentpresynapse

SYN3 WFS1 CNTNAP1 ADGRL1 SLC6A9 TENM3 OTOF SCAMP5 KCNH1 CLN3 SLC22A2 STON2 CNTNAP2 SYN1 SYN2 AP3D1

2.31e-0488613716GO:0098793
GeneOntologyCellularComponentasymmetric synapse

SYN3 SLITRK1 SLC6A9 KCNH1 ARHGEF9 CNTNAP2 LRP1 SYN1 SYN2 LRP4 PLCB4

3.12e-0447713711GO:0032279
GeneOntologyCellularComponentsynaptic membrane

GABRP TRPV1 ADGRL1 SLITRK1 SLC6A9 TENM3 OTOF KCNH1 SLC22A2 CNTNAP2 LRP1 LRP4

4.64e-0458313712GO:0097060
GeneOntologyCellularComponentapical part of cell

TRPM6 GABRP ABCC1 ENPP3 TEK SLC6A9 OTOF LMO7 SLC22A2 LRP1 ENPEP SLC38A3

5.32e-0459213712GO:0045177
GeneOntologyCellularComponentextrinsic component of synaptic vesicle membrane

SYN3 SYN1 SYN2

5.70e-04251373GO:0098850
GeneOntologyCellularComponentneuron to neuron synapse

SYN3 SLITRK1 SLC6A9 KCNH1 ARHGEF9 CNTNAP2 LRP1 SYN1 SYN2 LRP4 PLCB4

6.73e-0452313711GO:0098984
GeneOntologyCellularComponentpostsynaptic density

SYN3 SLITRK1 SLC6A9 KCNH1 ARHGEF9 LRP1 SYN1 SYN2 LRP4 PLCB4

7.93e-0445113710GO:0014069
GeneOntologyCellularComponentintraciliary transport particle

IFT140 IFT172 TTC21B

8.00e-04281373GO:0030990
GeneOntologyCellularComponentcytoplasmic vesicle membrane

ABCA3 SYN3 WFS1 COPB2 LAMP2 SLC6A9 OTOF SCAMP5 KCNH1 CLN3 SLC22A2 STON2 LRP1 SYN1 SYN2 CPNE1 AP3D1 ECE2 MVB12B

8.92e-04130713719GO:0030659
GeneOntologyCellularComponentcell surface

TRPV1 SLAMF9 ENPP3 SUCNR1 TEK GFRA1 PLA2R1 LMO7 KCNH1 CNTNAP2 CD40LG AOC3 LRP1 LRP4 ROS1 LY75 ENPEP

9.72e-04111113717GO:0009986
GeneOntologyCellularComponentvesicle membrane

ABCA3 SYN3 WFS1 COPB2 LAMP2 SLC6A9 OTOF SCAMP5 KCNH1 CLN3 SLC22A2 STON2 LRP1 SYN1 SYN2 CPNE1 AP3D1 ECE2 MVB12B

1.05e-03132513719GO:0012506
GeneOntologyCellularComponentintraciliary transport particle A

IFT140 TTC21B

1.16e-0381372GO:0030991
GeneOntologyCellularComponentapical plasma membrane

TRPM6 GABRP ABCC1 ENPP3 TEK SLC6A9 LMO7 SLC22A2 ENPEP SLC38A3

1.41e-0348713710GO:0016324
GeneOntologyCellularComponentclathrin-sculpted glutamate transport vesicle membrane

OTOF SYN1

1.49e-0391372GO:0060203
GeneOntologyCellularComponentclathrin-sculpted glutamate transport vesicle

OTOF SYN1

1.49e-0391372GO:0060199
GeneOntologyCellularComponentpostsynaptic specialization

SYN3 SLITRK1 SLC6A9 KCNH1 ARHGEF9 LRP1 SYN1 SYN2 LRP4 PLCB4

1.79e-0350313710GO:0099572
GeneOntologyCellularComponentinner dynein arm

DNAH10 DNAH1

1.85e-03101372GO:0036156
GeneOntologyCellularComponentparanodal junction

CNTNAP1 CNTNAP2

2.26e-03111372GO:0033010
GeneOntologyCellularComponentpresynaptic membrane

ADGRL1 SLC6A9 TENM3 OTOF KCNH1 SLC22A2 CNTNAP2

2.37e-032771377GO:0042734
GeneOntologyCellularComponentpresynaptic active zone

CNTNAP1 TENM3 OTOF CNTNAP2 SYN1

2.38e-031411375GO:0048786
GeneOntologyCellularComponentparallel fiber to Purkinje cell synapse

SLC6A9 KCNH1 PLCB4

2.81e-03431373GO:0098688
GeneOntologyCellularComponentextrinsic component of organelle membrane

SYN3 SYN1 SYN2

2.81e-03431373GO:0031312
GeneOntologyCellularComponentsecretory vesicle

ABCA3 SYN3 WFS1 UNC13D LAMP2 SLC6A9 OTOF SCAMP5 NAPRT CLN3 SLC22A2 STON2 LRP1 SYN1 SYN2 CPNE1 SSH2

3.26e-03124613717GO:0099503
GeneOntologyCellularComponentciliary tip

IFT140 IFT172 TTC21B

3.84e-03481373GO:0097542
GeneOntologyCellularComponentclathrin-sculpted vesicle

OTOF SYN1

4.82e-03161372GO:0060198
DomainSynapsin_pre-ATP-grasp_dom

SYN3 SYN1 SYN2

3.45e-0731323IPR020897
DomainSynapsin_ATP-bd_dom

SYN3 SYN1 SYN2

3.45e-0731323IPR020898
DomainSYNAPSIN_1

SYN3 SYN1 SYN2

3.45e-0731323PS00415
DomainSYNAPSIN_2

SYN3 SYN1 SYN2

3.45e-0731323PS00416
DomainSynapsin_C

SYN3 SYN1 SYN2

3.45e-0731323PF02750
DomainSynapsin_N

SYN3 SYN1 SYN2

3.45e-0731323PF10581
DomainSynapsin_CS

SYN3 SYN1 SYN2

3.45e-0731323IPR019735
DomainSynapsin_P_site

SYN3 SYN1 SYN2

3.45e-0731323IPR019736
DomainSynapsin

SYN3 SYN1 SYN2

3.45e-0731323PF02078
DomainSynapsin

SYN3 SYN1 SYN2

3.45e-0731323IPR001359
DomainEGF

RELN FAT3 CNTNAP1 TEK CNTNAP5 TENM3 TIE1 CNTNAP2 LRP1 LRP4

6.71e-0623513210SM00181
DomainEGF_3

RELN FAT3 CNTNAP1 TEK CNTNAP5 TENM3 TIE1 CNTNAP2 LRP1 LRP4

6.71e-0623513210PS50026
DomainEGF-like_dom

RELN FAT3 CNTNAP1 TEK CNTNAP5 TENM3 TIE1 CNTNAP2 LRP1 LRP4

1.11e-0524913210IPR000742
DomainEGF_1

RELN FAT3 CNTNAP1 TEK CNTNAP5 TENM3 TIE1 CNTNAP2 LRP1 LRP4

1.37e-0525513210PS00022
DomainEGF_2

RELN FAT3 CNTNAP1 TEK CNTNAP5 TENM3 TIE1 CNTNAP2 LRP1 LRP4

1.91e-0526513210PS01186
DomainGREB1

GREB1L GREB1

4.96e-0521322PF15782
DomainGREB1

GREB1L GREB1

4.96e-0521322IPR028422
Domain-

FAT3 CNTNAP1 ADGRG4 CNTNAP5 CNTNAP2 PAPPA

5.77e-059513262.60.120.200
Domain-

SYN3 SYN1 SYN2

9.37e-051313233.40.50.20
DomainEGF-like_CS

RELN FAT3 CNTNAP1 TEK TENM3 TIE1 CNTNAP2 LRP1 LRP4

1.01e-042611329IPR013032
DomainPreATP-grasp_dom

SYN3 SYN1 SYN2

1.19e-04141323IPR016185
DomainLAM_G_DOMAIN

FAT3 CNTNAP1 CNTNAP5 CNTNAP2

1.46e-04381324PS50025
DomainLY

LRP1 LRP4 ROS1

1.48e-04151323SM00135
Domain-

SYN3 SYN1 SYN2

1.48e-041513233.30.1490.20
DomainLDLR_classB_rpt

LRP1 LRP4 ROS1

1.48e-04151323IPR000033
Domain-

TENM3 LRP1 LRP4 ROS1

1.62e-043913242.120.10.30
DomainLaminin_G_2

FAT3 CNTNAP1 CNTNAP5 CNTNAP2

1.79e-04401324PF02210
DomainLamG

FAT3 CNTNAP1 CNTNAP5 CNTNAP2

2.60e-04441324SM00282
DomainATP_grasp_subdomain_1

SYN3 SYN1 SYN2

2.61e-04181323IPR013815
Domain-

SYN3 SYN1 SYN2

2.61e-041813233.30.470.20
DomainSAA

SAA1 SAA2

2.95e-0441322PS00992
DomainUbiquitin_3

USP11 USP4

2.95e-0441322PF14836
DomainUb_USP-typ

USP11 USP4

2.95e-0441322IPR028135
DomainSAA

SAA1 SAA2

2.95e-0441322SM00197
DomainTRPV1-4_channel

TRPV1 TRPV3

2.95e-0441322IPR008347
DomainSAA

SAA1 SAA2

2.95e-0441322PF00277
Domain6-blade_b-propeller_TolB-like

TENM3 LRP1 LRP4 ROS1

3.09e-04461324IPR011042
DomainFA58C

CNTNAP1 CNTNAP5 CNTNAP2

4.18e-04211323SM00231
DomainFA58C_3

CNTNAP1 CNTNAP5 CNTNAP2

4.18e-04211323PS50022
DomainFA58C_1

CNTNAP1 CNTNAP5 CNTNAP2

4.18e-04211323PS01285
DomainFA58C_2

CNTNAP1 CNTNAP5 CNTNAP2

4.18e-04211323PS01286
DomainSerum_amyloid_A

SAA1 SAA2

4.89e-0451322IPR000096
DomainF5_F8_type_C

CNTNAP1 CNTNAP5 CNTNAP2

6.26e-04241323PF00754
DomainFA58C

CNTNAP1 CNTNAP5 CNTNAP2

6.26e-04241323IPR000421
DomainDNA/RNA_non-sp_Endonuclease

ENPP3 EXOG

7.30e-0461322IPR001604
DomainHELP

EML4 EML3

7.30e-0461322PF03451
Domain-

ENPP3 EXOG

7.30e-04613223.40.570.10
DomainEndonuclease_NS

ENPP3 EXOG

7.30e-0461322PF01223
DomainExtracellular_endonuc_su_A

ENPP3 EXOG

7.30e-0461322IPR020821
DomainDUSP

USP11 USP4

7.30e-0461322PF06337
DomainNUC

ENPP3 EXOG

7.30e-0461322SM00477
DomainDUSP

USP11 USP4

7.30e-0461322SM00695
DomainEndonuclease_NS

ENPP3 EXOG

7.30e-0461322SM00892
DomainHELP

EML4 EML3

7.30e-0461322IPR005108
DomainLaminin_G

FAT3 CNTNAP1 CNTNAP5 CNTNAP2

7.53e-04581324IPR001791
DomainEGF_extracell

RELN TEK TENM3 TIE1

8.56e-04601324IPR013111
DomainEGF_2

RELN TEK TENM3 TIE1

8.56e-04601324PF07974
DomainConA-like_dom

FAT3 CNTNAP1 MDGA2 ADGRG4 CNTNAP5 CNTNAP2 PAPPA

9.46e-042191327IPR013320
DomainDUSP

USP11 USP4

1.02e-0371322PS51283
Domain-

USP11 USP4

1.02e-03713223.30.2230.10
DomainPept_C19_DUSP

USP11 USP4

1.02e-0371322IPR006615
DomainIon_trans_dom

TRPM6 TRPV1 KCNH4 KCNH1 TRPV3

1.30e-031141325IPR005821
DomainIon_trans

TRPM6 TRPV1 KCNH4 KCNH1 TRPV3

1.30e-031141325PF00520
DomainATP_grasp_subdomain_2

SYN3 SYN1 SYN2

1.34e-03311323IPR013816
DomainAlkaline_phosphatase_core

ENPP3 ARSI ARSH

1.34e-03311323IPR017850
DomainAlkaline_Pase-like_a/b/a

ENPP3 ARSI ARSH

1.34e-03311323IPR017849
Domain-

ENPP3 ARSI ARSH

1.34e-033113233.40.720.10
DomainERAP1-like_C_dom

LVRN ENPEP

1.35e-0381322IPR024571
DomainERAP1_C

LVRN ENPEP

1.35e-0381322PF11838
DomainFIBRINOGEN_C_1

CNTNAP1 CNTNAP5 CNTNAP2

1.47e-03321323PS00514
DomainFibrinogen_a/b/g_C_dom

CNTNAP1 CNTNAP5 CNTNAP2

1.47e-03321323IPR002181
DomainFIBRINOGEN_C_2

CNTNAP1 CNTNAP5 CNTNAP2

1.47e-03321323PS51406
DomainEGF

CNTNAP1 TIE1 CNTNAP2 LRP1 LRP4

2.02e-031261325PF00008
DomainGPS

PKD1L1 ADGRL1 ADGRG4

2.08e-03361323PS50221
DomainPAS_9

KCNH4 KCNH1

2.15e-03101322PF13426
DomainGPS

PKD1L1 ADGRL1 ADGRG4

2.25e-03371323IPR000203
DomainPeptidase_M1

LVRN ENPEP

3.12e-03121322IPR001930
DomainPeptidase_M1_N

LVRN ENPEP

3.67e-03131322IPR014782
DomainPeptidase_M1

LVRN ENPEP

3.67e-03131322PF01433
DomainDynein_heavy_chain_D4_dom

DNAH10 DNAH1

4.27e-03141322IPR024317
DomainFN_type2_col-bd

PLA2R1 LY75

4.27e-03141322IPR000562
DomainFN2_2

PLA2R1 LY75

4.27e-03141322PS51092
DomainDynein_HC_stalk

DNAH10 DNAH1

4.27e-03141322IPR024743
DomainDynein_heavy_dom-2

DNAH10 DNAH1

4.27e-03141322IPR013602
DomainDHC_N2

DNAH10 DNAH1

4.27e-03141322PF08393
DomainATPase_dyneun-rel_AAA

DNAH10 DNAH1

4.27e-03141322IPR011704
DomainFN2_1

PLA2R1 LY75

4.27e-03141322PS00023
DomainK_chnl_volt-dep_EAG/ELK/ERG

KCNH4 KCNH1

4.27e-03141322IPR003938
DomainMT

DNAH10 DNAH1

4.27e-03141322PF12777
DomainAAA_8

DNAH10 DNAH1

4.27e-03141322PF12780
DomainLdl_recept_b

LRP1 LRP4

4.27e-03141322PF00058
DomainLDLRB

LRP1 LRP4

4.27e-03141322PS51120
Domainfn2

PLA2R1 LY75

4.27e-03141322PF00040
DomainFN2

PLA2R1 LY75

4.27e-03141322SM00059
DomainNeurexin-like

CNTNAP1 CNTNAP2

4.27e-03141322IPR003585
Domain4.1m

CNTNAP1 CNTNAP2

4.27e-03141322SM00294
DomainAAA_5

DNAH10 DNAH1

4.27e-03141322PF07728
DomainDHC_fam

DNAH10 DNAH1

4.90e-03151322IPR026983
DomainDynein_heavy

DNAH10 DNAH1

4.90e-03151322PF03028
DomainDynein_heavy_dom

DNAH10 DNAH1

4.90e-03151322IPR004273
PathwayREACTOME_NEUROTRANSMITTER_RELEASE_CYCLE

MAOA SYN3 SLC22A2 SYN1 SYN2

4.66e-05511105M4281
PathwayREACTOME_NEUROTRANSMITTER_RELEASE_CYCLE

MAOA SYN3 SLC22A2 SYN1 SYN2

4.66e-05511105MM14499
Pubmed

Synapsin IIa controls the reserve pool of glutamatergic synaptic vesicles.

SYN3 SYN1 SYN2

6.11e-083138318945891
Pubmed

Different presynaptic roles of synapsins at excitatory and inhibitory synapses.

SYN3 SYN1 SYN2

6.11e-083138315601943
Pubmed

Compensatory network alterations upon onset of epilepsy in synapsin triple knock-out mice.

SYN3 SYN1 SYN2

6.11e-083138321621590
Pubmed

ERK activation in axonal varicosities modulates presynaptic plasticity in the CA3 region of the hippocampus through synapsin I.

SYN3 SYN1 SYN2

6.11e-083138319487674
Pubmed

Autism-related behavioral abnormalities in synapsin knockout mice.

SYN3 SYN1 SYN2

6.11e-083138323280234
Pubmed

Synapsin Isoforms Regulating GABA Release from Hippocampal Interneurons.

SYN3 SYN1 SYN2

6.11e-083138327335405
Pubmed

The Lack of Synapsin Alters Presynaptic Plasticity at Hippocampal Mossy Fibers in Male Mice.

SYN3 SYN1 SYN2

6.11e-083138338866497
Pubmed

Cortico-hippocampal hyperexcitability in synapsin I/II/III knockout mice: age-dependency and response to the antiepileptic drug levetiracetam.

SYN3 SYN1 SYN2

6.11e-083138320804820
Pubmed

Synapsins differentially control dopamine and serotonin release.

SYN3 SYN1 SYN2

6.11e-083138320660258
Pubmed

Synapsins regulate brain-derived neurotrophic factor-mediated synaptic potentiation and axon elongation by acting on membrane rafts.

SYN3 SYN1 SYN2

6.11e-083138328245069
Pubmed

Synapsin selectively controls the mobility of resting pool vesicles at hippocampal terminals.

SYN3 SYN1 SYN2

6.11e-083138322442064
Pubmed

Synapsin condensation controls synaptic vesicle sequestering and dynamics.

SYN3 SYN1 SYN2

6.11e-083138337872159
Pubmed

Molecular evolution of the synapsin gene family.

SYN3 SYN1 SYN2

6.11e-083138310578110
Pubmed

Maternal synapsin autoantibodies are associated with neurodevelopmental delay.

SYN3 SYN1 SYN2

6.11e-083138336742338
Pubmed

Synapsin-dependent reserve pool of synaptic vesicles supports replenishment of the readily releasable pool under intense synaptic transmission.

SYN3 SYN1 SYN2

6.11e-083138322805168
Pubmed

Epileptic synapsin triple knockout mice exhibit progressive long-term aberrant plasticity in the entorhinal cortex.

SYN3 SYN1 SYN2

6.11e-083138323236212
Pubmed

Synapsin 2a tetramerisation selectively controls the presynaptic nanoscale organisation of reserve synaptic vesicles.

SYN3 SYN1 SYN2

6.11e-083138338472171
Pubmed

The readily-releasable pool dynamically regulates multivesicular release.

SYN3 SYN1 SYN2

6.11e-083138331364987
Pubmed

DNA hypomethylation of Synapsin II CpG islands associates with increased gene expression in bipolar disorder and major depression.

SYN3 SYN1 SYN2

6.11e-083138327515700
Pubmed

Synapsins contribute to the dynamic spatial organization of synaptic vesicles in an activity-dependent manner.

SYN3 SYN1 SYN2

6.11e-083138322933803
Pubmed

Synaptic vesicle mobility in mouse motor nerve terminals with and without synapsin.

SYN3 SYN1 SYN2

6.11e-083138318077680
Pubmed

The Knockout of Synapsin II in Mice Impairs Social Behavior and Functional Connectivity Generating an ASD-like Phenotype.

SYN3 SYN1 SYN2

6.11e-083138328922833
Pubmed

Temporal evolution of neurophysiological and behavioral features of synapsin I/II/III triple knock-out mice.

SYN3 SYN1 SYN2

6.11e-083138322846639
Pubmed

Synaptic and extrasynaptic origin of the excitation/inhibition imbalance in the hippocampus of synapsin I/II/III knockout mice.

SYN3 SYN1 SYN2

6.11e-083138322368083
Pubmed

Cocaine increases dopamine release by mobilization of a synapsin-dependent reserve pool.

SYN3 SYN1 SYN2

6.11e-083138316554471
Pubmed

Neuronal nitric-oxide synthase localization mediated by a ternary complex with synapsin and CAPON.

SYN3 SYN1 SYN2

6.08e-075138311867766
Pubmed

Homo- and heterodimerization of synapsins.

SYN3 SYN1 SYN2

6.08e-075138310358015
Pubmed

Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.

DNAH10 MDGA2 TEK GFRA1 CNTNAP5 TENM3 CNTNAP2 C13orf42

1.40e-06199138823382691
Pubmed

Establishment and Dysfunction of the Blood-Brain Barrier.

ABCC1 SLC6A9 SLC22A2 LRP1 SLC38A3

2.05e-0652138526590417
Pubmed

Molecular determinants of synapsin targeting to presynaptic terminals.

SYN3 SYN1 SYN2

3.37e-068138315071120
Pubmed

Development of the mouse neuromuscular junction in the absence of regulated secretion.

SYN3 SYN1 SYN2

3.37e-068138312895513
Pubmed

A quantitative analysis of the spatiotemporal pattern of transient receptor potential gene expression in the developing mouse cochlea.

TRPM6 TRPV1 PKD1L1 TRPV3

8.88e-0633138419834762
Pubmed

Integral and associated lysosomal membrane proteins.

LAMP2 CLN3 LRP1 DEPDC5 ENPEP AP3D1

1.17e-05126138617897319
Pubmed

Polymorphisms in the SAA1/2 gene are associated with carotid intima media thickness in healthy Han Chinese subjects: the Cardiovascular Risk Survey.

SAA1 SAA2

1.56e-052138221103356
Pubmed

The rate and significance of type 1/type 2 serum amyloid A protein gene polymorphisms in patients with ankylosing spondylitis and amyloidosis.

SAA1 SAA2

1.56e-052138226300108
Pubmed

Seizure elements and seizure element transitions during tonic-clonic seizure activity in the synapsin I/II double knockout mouse: a neuroethological description.

SYN1 SYN2

1.56e-052138219236947
Pubmed

DNA sequence evidence for polymorphic forms of human serum amyloid A (SAA).

SAA1 SAA2

1.56e-05213823800865
Pubmed

Serum Amyloid A Induces Inflammation, Proliferation and Cell Death in Activated Hepatic Stellate Cells.

SAA1 SAA2

1.56e-052138226937641
Pubmed

The importance of synapsin I and II for neurotransmitter levels and vesicular storage in cholinergic, glutamatergic and GABAergic nerve terminals.

SYN1 SYN2

1.56e-052138219428802
Pubmed

Synapsin-dependent development of glutamatergic synaptic vesicles and presynaptic plasticity in postnatal mouse brain.

SYN1 SYN2

1.56e-052138218606212
Pubmed

Evidence for heterotypic interaction between the receptor tyrosine kinases TIE-1 and TIE-2.

TEK TIE1

1.56e-052138210995770
Pubmed

Molecular cloning and characterization of mouse TIE and TEK receptor tyrosine kinase genes and their expression in hematopoietic stem cells.

TEK TIE1

1.56e-05213828395828
Pubmed

Glutamatergic neurotransmission in the synapsin I and II double knock-out mouse.

SYN1 SYN2

1.56e-052138221827868
Pubmed

Influence of Serum Amyloid A (SAA1) and SAA2 gene polymorphisms on renal amyloidosis, and on SAA/C-reactive protein values in patients with familial mediterranean fever in the Turkish population.

SAA1 SAA2

1.56e-052138215170927
Pubmed

Acute-phase, but not constitutive serum amyloid A (SAA) is chemotactic for cultured human aortic smooth muscle cells.

SAA1 SAA2

1.56e-052138212557751
Pubmed

Serum amyloid alpha 1-2 are not required for liver inflammation in the 4T1 murine breast cancer model.

SAA1 SAA2

1.56e-052138236817472
Pubmed

Association of genetic variation in serum amyloid-A with cardiovascular disease and interactions with IL6, IL1RN, IL1beta and TNF genes in the Cardiovascular Health Study.

SAA1 SAA2

1.56e-052138219729864
Pubmed

Synapsins I and II are ATP-binding proteins with differential Ca2+ regulation.

SYN1 SYN2

1.56e-05213829430678
Pubmed

Genetic and pharmacological evidence for low-abundance TRPV3 expression in primary vagal afferent neurons.

TRPV1 TRPV3

1.56e-052138226843581
Pubmed

Localization of the angiopoietin receptors Tie-1 and Tie-2 on the primary cilia in the female reproductive organs.

TEK TIE1

1.56e-052138215893943
Pubmed

No evidence for a role of adipose tissue-derived serum amyloid a in the development of insulin resistance or obesity-related inflammation in hSAA1(+/-) transgenic mice.

SAA1 SAA2

1.56e-052138223967285
Pubmed

Monoamine oxidase and semicarbazide-sensitive amine oxidase kinetic analysis in mesenteric arteries of patients with type 2 diabetes.

MAOA AOC3

1.56e-052138221114364
Pubmed

Diversity and complexity of the mouse Saa1 and Saa2 genes.

SAA1 SAA2

1.56e-052138224521869
Pubmed

Synapsin II and calcium regulate vesicle docking and the cross-talk between vesicle pools at the mouse motor terminals.

SYN1 SYN2

1.56e-052138218669537
Pubmed

Heterogeneity of human serum amyloid A protein. Five different variants from one individual demonstrated by cDNA sequence analysis.

SAA1 SAA2

1.56e-05213821971508
Pubmed

Serum amyloid A induces calcium mobilization and chemotaxis of human monocytes by activating a pertussis toxin-sensitive signaling pathway.

SAA1 SAA2

1.56e-05213827561109
Pubmed

Synapsins regulate use-dependent synaptic plasticity in the calyx of Held by a Ca2+/calmodulin-dependent pathway.

SYN1 SYN2

1.56e-052138216481620
Pubmed

Human serum amyloid A. Three hepatic mRNAs and the corresponding proteins in one person.

SAA1 SAA2

1.56e-05213823183061
Pubmed

Complete primary structures of two major murine serum amyloid A proteins deduced from cDNA sequences.

SAA1 SAA2

1.56e-05213823857624
Pubmed

FGF13 enhances the function of TRPV1 by stabilizing microtubules and regulates acute and chronic itch.

TRPV1 FGF13

1.56e-052138238733310
Pubmed

SNP variants within the vanilloid TRPV1 and TRPV3 receptor genes are associated with migraine in the Spanish population.

TRPV1 TRPV3

1.56e-052138222162417
Pubmed

Activation of the orphan endothelial receptor Tie1 modifies Tie2-mediated intracellular signaling and cell survival.

TEK TIE1

1.56e-052138217504972
Pubmed

Distinct changes in neuronal and astrocytic amino acid neurotransmitter metabolism in mice with reduced numbers of synaptic vesicles.

SYN1 SYN2

1.56e-052138218346203
Pubmed

Serum amyloid A protein induces production of matrix metalloproteinases by human synovial fibroblasts.

SAA1 SAA2

1.56e-05213829605178
Pubmed

Exome-wide Association Study Identifies GREB1L Mutations in Congenital Kidney Malformations.

GREB1L GREB1

1.56e-052138229100090
Pubmed

Long-term potentiation in mice lacking synapsins.

SYN1 SYN2

1.56e-05213828606805
Pubmed

Ultrastructural quantification of glutamate receptors at excitatory synapses in hippocampus of synapsin I+II double knock-out mice.

SYN1 SYN2

1.56e-052138216344150
Pubmed

Synapsins: mosaics of shared and individual domains in a family of synaptic vesicle phosphoproteins.

SYN1 SYN2

1.56e-05213822506642
Pubmed

Absence of synapsin I and II is accompanied by decreases in vesicular transport of specific neurotransmitters.

SYN1 SYN2

1.56e-052138216478532
Pubmed

Tie1-Tie2 interactions mediate functional differences between angiopoietin ligands.

TEK TIE1

1.56e-052138220227369
Pubmed

Serum amyloid A is a soluble pattern recognition receptor that drives type 2 immunity.

SAA1 SAA2

1.56e-052138232572240
Pubmed

Acute heat-evoked temperature sensation is impaired but not abolished in mice lacking TRPV1 and TRPV3 channels.

TRPV1 TRPV3

1.56e-052138224925072
Pubmed

Effect of serum amyloid A on selected in vitro functions of isolated human neutrophils.

SAA1 SAA2

1.56e-05213829823935
Pubmed

AA amyloidosis-resistant CE/J mice have Saa1 and Saa2 genes that encode an identical SAA isoform.

SAA1 SAA2

1.56e-052138224228751
Pubmed

The frequencies of the serum amyloid A2 alleles in healthy (Turkish, Azerbaijan and Kazakh) populations.

SAA1 SAA2

1.56e-052138216152805
Pubmed

Differential glucocorticoid enhancement of the cytokine-driven transcriptional activation of the human acute phase serum amyloid A genes, SAA1 and SAA2.

SAA1 SAA2

1.56e-052138212077270
Pubmed

Regulation of the human acute phase serum amyloid A genes by tumour necrosis factor-alpha, interleukin-6 and glucocorticoids in hepatic and epithelial cell lines.

SAA1 SAA2

1.56e-052138214871291
Pubmed

Isolation and purification of two major serum amyloid A isotypes SAA1 and SAA2 from the acute phase plasma of mice.

SAA1 SAA2

1.56e-05213829518179
Pubmed

Sensitive and critical periods in the development of handling induced seizures in mice lacking synapsins: differences between synapsin I and synapsin II knockouts.

SYN1 SYN2

1.56e-052138223570901
Pubmed

Structural prerequisites for serum amyloid A fibril formation.

SAA1 SAA2

1.56e-05213828376413
Pubmed

A Gene Implicated in Activation of Retinoic Acid Receptor Targets Is a Novel Renal Agenesis Gene in Humans.

GREB1L GREB1

1.56e-052138228739660
Pubmed

Tie-1: A potential target for anti-angiogenesis therapy.

TEK TIE1

1.56e-052138226489611
Pubmed

Synapsin I and Synapsin II regulate neurogenesis in the dentate gyrus of adult mice.

SYN1 SYN2

1.56e-052138229721159
Pubmed

Serum Amyloid A Promotes Inflammation-Associated Damage and Tumorigenesis in a Mouse Model of Colitis-Associated Cancer.

SAA1 SAA2

1.56e-052138234217896
Pubmed

Serum amyloid A, an acute phase protein, inhibits platelet activation.

SAA1 SAA2

1.56e-05213821697614
Pubmed

A new kinetic framework for synaptic vesicle trafficking tested in synapsin knock-outs.

SYN1 SYN2

1.56e-052138221832187
Pubmed

Serum amyloid A facilitates the binding of high-density lipoprotein from mice injected with lipopolysaccharide to vascular proteoglycans.

SAA1 SAA2

1.56e-052138221474830
Pubmed

Electroencephalographic characterization of seizure activity in the synapsin I/II double knockout mouse.

SYN1 SYN2

1.56e-052138221281619
Pubmed

Structure of a human serum amyloid A gene and modulation of its expression in transfected L cells.

SAA1 SAA2

1.56e-05213822890635
Pubmed

Acute-phase serum amyloid A: an inflammatory adipokine and potential link between obesity and its metabolic complications.

SAA1 SAA2

1.56e-052138216737350
Pubmed

Murine apolipoprotein serum amyloid A in solution forms a hexamer containing a central channel.

SAA1 SAA2

1.56e-052138212456883
Pubmed

The Impairment of Macrophage-to-Feces Reverse Cholesterol Transport during Inflammation Does Not Depend on Serum Amyloid A.

SAA1 SAA2

1.56e-052138223431457
Pubmed

Synapsin dispersion and reclustering during synaptic activity.

SYN1 SYN2

1.56e-052138211685225
Pubmed

Large-scale isotype-specific quantification of Serum amyloid A 1/2 by multiple reaction monitoring in crude sera.

SAA1 SAA2

1.56e-052138222300576
Pubmed

Extracellular matrix-anchored serum amyloid A preferentially induces mast cell adhesion.

SAA1 SAA2

1.56e-05213829252455
Pubmed

Inflammatory remodeling of the HDL proteome impairs cholesterol efflux capacity.

SAA1 SAA2

1.56e-052138225995210
Pubmed

Linkage of protection against amyloid fibril formation in the mouse to a single, autosomal dominant gene.

SAA1 SAA2

1.56e-05213827760010
Pubmed

Serum amyloid A exhibits pH dependent antibacterial action and contributes to host defense against Staphylococcus aureus cutaneous infection.

SAA1 SAA2

1.56e-052138231819008
Pubmed

SAA does not induce cytokine production in physiological conditions.

SAA1 SAA2

1.56e-052138223165195
Pubmed

The receptor tyrosine kinase TIE is required for integrity and survival of vascular endothelial cells.

TEK TIE1

1.56e-05213828846781
InteractionSYN3 interactions

SYN3 PIAS2 CNTNAP2 SYN1 SYN2

8.94e-08181325int:SYN3
GeneFamilySynapsins

SYN3 SYN1 SYN2

1.19e-0739031325
GeneFamilyIntraflagellar transport proteins|Tetratricopeptide repeat domain containing

IFT140 IFT172 TTC21B

2.24e-0424903615
GeneFamilyTransient receptor potential cation channels

TRPM6 TRPV1 TRPV3

3.57e-0428903249
GeneFamilyReceptor Tyrosine Kinases|CD molecules

TEK TIE1 ROS1

1.03e-0340903321
GeneFamilyLow density lipoprotein receptors

LRP1 LRP4

1.84e-0313902634
GeneFamilyDyneins, axonemal

DNAH10 DNAH1

3.17e-0317902536
GeneFamilyAminopeptidases|CD molecules

LVRN ENPEP

3.17e-0317902104
GeneFamilyADAM metallopeptidase domain containing|CD molecules

ENPP3 LAMP2 TEK CD40LG LRP1 LY75 ENPEP

3.51e-03394907471
GeneFamilySulfatases

ARSI ARSH

3.56e-0318902410
CoexpressionDELYS_THYROID_CANCER_DN

RELN WWOX WFS1 NEB TEK PLA2R1 IPCEF1 AOC3 FGF13

3.74e-062331369M13273
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HGABA

RELN ABCA3 SYN3 ARFGEF1 ADGRL1 MDGA2 NEB PIAS2 SLITRK1 GFRA1 RUSC2 KLHL13 RABGAP1L CNTNAP2 SYN2 PAPPA PLCB4 SSH2 MVB12B

4.58e-06110613619M39071
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN DNAH10 FAT3 MDGA2 NEB DNAH1 ROS1 UNC80

1.13e-0718413882cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN DNAH10 FAT3 MDGA2 NEB DNAH1 ROS1 UNC80

1.13e-071841388ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN DNAH10 FAT3 MDGA2 NEB DNAH1 ROS1 UNC80

1.13e-0718413882b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DNAH10 FAT3 MDGA2 NEB CNTNAP5 ROS1 UNC80

7.52e-071621387bf886e22ff2a20353499004b53f25fb9e6574896
ToppCellRV-11._Adipocyte|World / Chamber and Cluster_Paper

LVRN MAOA ACSS2 SAA1 TENM3 FGF13 TMEM164

1.36e-061771387f0edf04930692418953e4f00a917257804ec0ffd
ToppCellLA-11._Adipocyte|LA / Chamber and Cluster_Paper

LVRN MAOA ACSS2 SAA1 TENM3 FGF13 TMEM164

1.70e-0618313873f9011976782fa8aa95cdd6f00f07a91094d411b
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAT3 GFRA1 SPON2 LRP1 LRP4 DAAM2 PAPPA

1.70e-0618313877eae9b3b4d1c9b135fa7cff348393d4adec474b4
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

RELN TENM3 KCNH1 KLHL13 PAPPA PLCB4 UNC80

1.83e-0618513877dcdc009c5681ee05dd18968f7e85c3403fe34af
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAT3 GFRA1 KLHL13 LRP1 LRP4 DAAM2 PAPPA

2.10e-06189138745e588b2a4ad9e3ff74e22d9d627ed3571f3b8b8
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RELN CNTNAP1 TENM3 CNTNAP2 PAPPA PLCB4 ENPEP

2.96e-06199138783383d9ae4f501754fd3da0215ce6f0e3c70562c
ToppCellStriatum-Neuronal|Striatum / BrainAtlas - Mouse McCarroll V32

ASPHD1 KCNH1 ARHGEF9 CNTNAP2 SYN1 SYN2 AP3D1

3.06e-062001387c888fd487990cad482a4ca47601cdebc0ca3f3ce
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ABCA3 CLIC6 SAA1 SAA2 LRRIQ1 LMO7 ROS1

3.06e-06200138721d9cf3cd3696ad6b745c7c036798f04b6ce5160
ToppCellLung_Parenchyma-Severe-Epithelial|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

ABCA3 CLIC6 SAA1 SAA2 LRRIQ1 LMO7 ROS1

3.06e-06200138733658d5d09e2eaff60f4dd88837d4252328eab63
ToppCellParenchyma_COVID-19-Epithelial-TX|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

ABCA3 CLIC6 SAA1 SAA2 LRRIQ1 LMO7 ROS1

3.06e-062001387d5426cd318a8f90c0bd8f9804351ab230fafc995
ToppCellCOVID-19-kidney-Technical/muscle_(EC)|kidney / Disease (COVID-19 only), tissue and cell type

RELN SYN3 MDGA2 ADGRG4 CNTNAP5 CNTNAP2

4.80e-06139138664c35411bbe67acb5010dadc4b0b1be0f8b17737
ToppCellThalamus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3|Thalamus / BrainAtlas - Mouse McCarroll V32

SAA1 SAA2 SPON2 AOC3 ENPEP

6.05e-068313854017af9a4804a06d0f2cd0f285ebf1b582b751de
ToppCellThalamus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Car4_(Mural.Rgs5Acta2.Car4)|Thalamus / BrainAtlas - Mouse McCarroll V32

SAA1 SAA2 SPON2 AOC3 ENPEP

6.05e-0683138559fce941d45f9763a8584f3fd5b7c0738de9f592
ToppCellThalamus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Car4_(Mural.Rgs5Acta2.Car4)-|Thalamus / BrainAtlas - Mouse McCarroll V32

SAA1 SAA2 SPON2 AOC3 ENPEP

6.05e-06831385ebabce70dc01fdeda7fccebc2c4a0b686cda580f
ToppCellCOVID-19-kidney-Technical/muscle_(PCT)|kidney / Disease (COVID-19 only), tissue and cell type

RELN SYN3 MDGA2 CNTNAP5 CNTNAP2 TRPV3

6.36e-061461386c55f1bdb6ac43b4118cb27ea7c879527e1afcbab
ToppCellCOVID-19-Epithelial_cells-Airway_mucous|COVID-19 / group, cell type (main and fine annotations)

DNAH10 CLIC6 LRRIQ1 LMO7 CNTNAP2 FGF13

7.72e-0615113868216462e723fec2797387929dde095370947e10a
ToppCelldroplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM6 RELN GRAMD1A EML3 UBE4A LCOR

9.64e-061571386a426c54fd1545093d41426e9620862f71bd06f6b
ToppCellCOVID-19-kidney-Technical/muscle_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type

RELN FAT3 MDGA2 GREB1L CNTNAP5 CNTNAP2

1.04e-0515913865335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCellCOVID-19-kidney-Technical/muscle_(Imm)|kidney / Disease (COVID-19 only), tissue and cell type

RELN SYN3 MDGA2 GREB1L CNTNAP5 CNTNAP2

1.19e-05163138619c28ce16a588a7f4a035c32726f6ccd67702b5b
ToppCellfacs-Large_Intestine-Distal-3m-Epithelial-enterocyte_of_epithelium_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM6 SAA1 SAA2 LMO7 STON2 TRPV3

1.42e-05168138603896466698a79f7f1ad862cb7e05585260e2a5a
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH10 FAT3 KCNH4 DNAH1 CNTNAP2 UNC80

1.47e-05169138612bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCellE15.5-Epithelial-epithelial_progenitor_cell-epithelial_unknown_3|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MDGA2 GFRA1 CNTNAP5 SYN1 SYN2 FGF13

1.62e-051721386a8b33d8ebc56e442a2ad6ac7dafd0c887571bd95
ToppCellAdult-Endothelial-endothelial_cell_of_lymph_vessel-D231|Adult / Lineage, Cell type, age group and donor

RELN TEK TENM3 TIE1 STON2 PLCB4

1.97e-051781386c80ca7a2d3f976089a5e71d0cd9ba9a1c0bd2815
ToppCelldroplet-Lung-LUNG-30m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MDGA2 HID1 TEK TIE1 LMO7 PLCB4

2.03e-051791386a09647750eba9d93c5efc1db3b555fefb5eec7b5
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CNTNAP1 SPON2 KLHL13 LRP1 LRP4 DAAM2

2.03e-05179138602c90d8306016365ed811f0c63cfb3ac7b85464c
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH10 CNTNAP1 DNAH1 SAA1 SAA2 LRRIQ1

2.09e-05180138692fb01b91261b3103454924cde56add337b41844
ToppCellRA-11._Adipocyte|RA / Chamber and Cluster_Paper

LVRN ACSS2 SAA1 TENM3 SYN2 FGF13

2.09e-051801386d48a3d27357f7d184132a6805950f93080146b59
ToppCellMesenchymal_cells-Stromal_fibro.|Mesenchymal_cells / Lineage and Cell class

RELN CLIC6 GFRA1 SAA1 SAA2 GREB1

2.16e-051811386f8d914fdc06aaa75a4dc9158daf574ca28fa5432
ToppCell5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RELN WFS1 TENM3 TIE1 IPCEF1 STON2

2.23e-05182138653c267ee327e116dbd89d5927ed3bdf78d25ee62
ToppCellLA-11._Adipocyte|World / Chamber and Cluster_Paper

LVRN ACSS2 SAA1 TENM3 FGF13 TMEM164

2.30e-051831386b177be283e1553fb1f69a346f1ba79ad00297fa2
ToppCell5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RELN WFS1 TENM3 TIE1 IPCEF1 STON2

2.30e-0518313864d16bfbadf2cd13008c35e23dd2b5b4ecf92ee11
ToppCellP03-Endothelial-lymphatic_endothelial_cell-endothelial_cell_of_lymphatic_vessel|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

RELN ENPP3 GRAMD1A PTPN18 TIE1 FGF13

2.30e-05183138689727b4f65949ed2dce9d2e0228c79fe4280230c
ToppCellP03-Endothelial-lymphatic_endothelial_cell|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

RELN ENPP3 GRAMD1A PTPN18 TIE1 FGF13

2.30e-051831386113e6d8d4bb271be984af06cd6c22b180425dcfc
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN GFRA1 ARHGEF9 SYN1 DAAM2 PAPPA

2.30e-0518313868330c39184ce076e1f95fd3725b68af551d89db0
ToppCellfacs-Skin-Skin_Anagen-18m-Mesenchymal-fibroblast|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LVRN ENPP3 RUSC2 PLA2R1 DAAM2 ENPEP

2.37e-051841386fea4fe648e9749177d0783443dc26a7df5807883
ToppCelldroplet-Lung-30m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MDGA2 TEK LRRIQ1 TIE1 LMO7 PLCB4

2.37e-051841386f506d0ee48f39d6f59f19554217dfdf0987cc405
ToppCelldroplet-Lung-30m-Endothelial-arterial_endothelial|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MDGA2 TEK LRRIQ1 TIE1 LMO7 PLCB4

2.37e-0518413868bcb1c4bc8ffef74338cdade926a94711de93c64
ToppCellfacs-Skin-Skin_Anagen-18m-Mesenchymal-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LVRN ENPP3 RUSC2 PLA2R1 DAAM2 ENPEP

2.37e-05184138696a8a0a190bc293655fe7d80cbed8119c0da25f2
ToppCellfacs-Skin-Skin_Anagen-18m-Mesenchymal|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LVRN ENPP3 RUSC2 PLA2R1 DAAM2 ENPEP

2.37e-051841386780eb72da43527f0c72effac3423ec7384f05f20
ToppCellpdx-Tumor_cells-T0|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

RELN WWOX TENM3 LRP1 GREB1 TNS3

2.44e-0518513861d874608aa2062024323512f68889219471b2f00
ToppCellMesenchymal_cells-Osteo-CAR|World / Lineage and Cell class

LMO7 KCNH1 SLC22A2 LRP4 PAPPA TNS3

2.44e-05185138616f1588893d09c864e0cb4f837a1b972a1a57baa
ToppCell5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RELN WFS1 TENM3 TIE1 IPCEF1 STON2

2.52e-05186138640070d9cd20188ba49b32acfca9bc16256b38bf5
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RELN TENM3 OTOF CNTNAP2 PAPPA ECE2

2.59e-05187138685f1678338a47d91e296f0620d4887f057eb7e70
ToppCellCerebellum-Neuronal|Cerebellum / BrainAtlas - Mouse McCarroll V32

ASPHD1 SLITRK1 ARHGEF9 CNTNAP2 SYN1 UNC80

2.59e-05187138661b9d6eb131a674598aa8409d7fa909c8765442d
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ABCA3 MAOA FAAH2 LMO7 ROS1 TMEM164

2.59e-0518713865df9e1f5ca32217af255e76e6fb5afa346337811
ToppCellRA-11._Adipocyte|World / Chamber and Cluster_Paper

LVRN ACSS2 SAA1 TENM3 SYN2 FGF13

2.67e-0518813864dac9d636e5cad4cda540b93d4bfed6b5732c880
ToppCelldroplet-Heart-nan-3m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYN3 HID1 TEK DNAH1 GREB1L SLC22A2

2.75e-0518913868e583ec4df0f5b79ce5211cc99ecd8616d180bde
ToppCelldroplet-Heart-nan-3m-Endothelial-endocardial_endothelial_cells|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYN3 HID1 TEK DNAH1 GREB1L SLC22A2

2.75e-051891386fb2253b8463d08b3d28e952a31a23dea2c2d986b
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

PLA2R1 TENM3 SPON2 CNTNAP2 PAPPA ENPEP

2.84e-0519013864f775ee24b14733f06ae40b45f2dc1a0f0df0705
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAT3 ARSI GFRA1 TENM3 LRP1 PAPPA

2.92e-051911386b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCellControl-Stromal_mesenchymal|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAT3 GFRA1 LRP1 LRP4 DAAM2 PAPPA

2.92e-05191138614057205ddb9b4bbc582d1358d13cf36d979a61b
ToppCelldroplet-Heart-nan-18m-Endothelial-endocardial_endothelial_cells|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UNC13D HID1 TEK GREB1L TMEM164 ATL2

3.01e-0519213860b9b2eaed45456d7d74ce78a64ef4a26ac2458fb
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RELN PLA2R1 OTOF CNTNAP2 PAPPA ECE2

3.01e-051921386dc40ef2341e5d6a6d479f140e023fe1bf687928d
ToppCelldroplet-Spleen-nan-18m-Lymphocytic-plasma_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN WFS1 GPR55 HID1 STT3A TNS3

3.01e-0519213866417468829517a0f6e04e7e44eec1622001d4c5c
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RELN TENM3 OTOF CNTNAP2 PAPPA ECE2

3.10e-051931386010717ca052b6c8a525a43aaeffddea0d1113e63
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

LVRN RELN SPON2 CNTNAP2 PAPPA ENPEP

3.10e-051931386cd45118ced91b10baed3b1068d4673ec99824b86
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

GABRP LMO7 IPCEF1 KLHL13 FGF13 SSH2

3.10e-051931386f42a0f02ed00fe1bb833ff0a0640d9131bca89bd
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

TENM3 SPON2 KLHL13 CNTNAP2 PAPPA ENPEP

3.10e-051931386adc9fc94f9ec686a417d08c0b8b7b7ab687afec0
ToppCellfacs-Mammary_Gland-Mammary_Gland-18m-Epithelial-luminal_epithelial_cell_of_mammary_gland|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GABRP ENPP3 MDGA2 CLIC6 HID1 PTPN18

3.10e-0519313861526f51b589a7dc7a28f35f0e788dc38d338d2bc
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

GABRP LMO7 IPCEF1 KLHL13 FGF13 SSH2

3.10e-05193138642df7ed37d11fb542b4d1d714b6f87ae8e1396a6
ToppCell10x3'2.3-week_17-19-Myeloid_neutrophil-granulo-eo/baso/mast-basophil|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

GABRP ABCC1 GALC SYN3 RUSC2 TMEM164

3.19e-0519413865da8873cddff582e5693b32fd3aaebc102f65fc0
ToppCell5'-Adult-SmallIntestine-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RELN WFS1 LRRIQ1 TIE1 IPCEF1 STON2

3.19e-051941386937ee85ffd50869b60f0f6e91017ab77e8b24c0b
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

GABRP LMO7 IPCEF1 KLHL13 FGF13 SSH2

3.19e-051941386e577d9e88390b36b5a09b97fe1026089892275a3
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GABRP FAAH2 IPCEF1 KLHL13 FGF13 SSH2

3.28e-051951386938b31dbf1674ee6fd0123bc88391ddcaf151217
ToppCell10x3'2.3-week_17-19-Mesenchymal_osteo-stroma-osteoblast_precursor|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

FAT3 GFRA1 TENM3 CNTNAP2 LRP1 LRP4

3.28e-051951386ec12cfb2fce44cc2de4e198ef5af075e626f0329
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GABRP FAAH2 IPCEF1 KLHL13 FGF13 SSH2

3.28e-051951386d39e9e6544f49e677ebe528c6fe60b99a3630e30
ToppCelldroplet-Heart-nan-18m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UNC13D HID1 TEK GREB1L TMEM164 ATL2

3.38e-051961386e386526332138e636aef2542c11316347a45689c
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.2.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCA3 MAOA ACSS2 SAA1 SAA2 ROS1

3.47e-051971386d2a4d7e92e91bcc47a7657da2e5c8a3ad7eb08ad
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_neuro-secretory-Ionocyte_n_Brush|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FAT3 HID1 SLC6A9 SCAMP5 KCNH1 FGF13

3.57e-051981386dd0465b45b02cb8edf0914d19afb52fcaaeb012c
ToppCellSubstantia_nigra-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

PLA2R1 SAA1 SAA2 ENPEP MUTYH

3.62e-051201385e60b74758c8290919b326904ad841962256b72ec
ToppCellSubstantia_nigra-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2-MURAL_Mural.Rgs5Acta2.Kcnj8_(Mural.Rgs5Acta2.Kcnj8)-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

PLA2R1 SAA1 SAA2 ENPEP MUTYH

3.62e-0512013853e1ae5a5422729d484a90d72f779833fe3473fa8
ToppCellSubstantia_nigra-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2-MURAL_Mural.Rgs5Acta2.Kcnj8_(Mural.Rgs5Acta2.Kcnj8)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

PLA2R1 SAA1 SAA2 ENPEP MUTYH

3.62e-05120138524d5e86931a857bb87684392172bf04294a1a46a
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MDGA2 TEK GFRA1 CNTNAP5 LRP1 UNC80

3.67e-051991386333056c2abe9724efeab542c0365fcfe4eff8f18
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TEK GFRA1 CNTNAP5 LRP1 LRP4 UNC80

3.67e-05199138619a97e27a4758e794ce7246d295e112b47931a48
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MDGA2 TEK GFRA1 CNTNAP5 LRP1 UNC80

3.67e-051991386e60ecbb8fa7bcd3e2ce7d78f6efb2cfd1fd77698
ToppCellFrontal_cortex-Neuronal|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ADGRL1 RABGAP1L ARHGEF9 SYN1 SYN2 UNC80

3.67e-051991386f88039d862f3bfa01dc39d2de4f3f548dc5a0e61
ToppCellParenchymal-10x3prime_v2-Epithelial-Epi_submucosal-gland|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

GABRP CLIC6 FAAH2 PLA2R1 SAA1 SAA2

3.78e-05200138668b0f987c4fb8078675475f4f1e71302f832ef69
ToppCellParenchymal-10x3prime_v2-Epithelial-Epi_submucosal-gland-SMG_Duct|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

GABRP CLIC6 FAAH2 PLA2R1 SAA1 SAA2

3.78e-0520013861b527bebbca1ef8c52449e40beb9358e37494e04
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MDGA2 TEK GFRA1 CNTNAP5 CNTNAP2 LRP1

3.78e-052001386ad777683adeb2ce45ade570386235e311fa7ea2d
ToppCellCOVID-19-kidney-Epithelial_(EC)|COVID-19 / Disease (COVID-19 only), tissue and cell type

MDGA2 TEK SLITRK1 CNTNAP5 CNTNAP2

5.92e-051331385a8abb6b54862123961ae6defbf251ee6e9575258
ToppCellCerebellum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2|Cerebellum / BrainAtlas - Mouse McCarroll V32

ZBTB49 PLA2R1 SAA1 SAA2 ENPEP

6.82e-0513713859324b55eac55e0cc1e8e450a4b5374d12e9587a3
ToppCellCerebellum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2-MURAL_Mural.Acta2Rgs5.Kcnj8_(Mural.Acta2Rgs5.Kcnj8)|Cerebellum / BrainAtlas - Mouse McCarroll V32

ZBTB49 PLA2R1 SAA1 SAA2 ENPEP

6.82e-051371385032f8409d0d179e254c8ff632afbda78852a9889
ToppCellCerebellum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2-MURAL_Mural.Acta2Rgs5.Kcnj8_(Mural.Acta2Rgs5.Kcnj8)-|Cerebellum / BrainAtlas - Mouse McCarroll V32

ZBTB49 PLA2R1 SAA1 SAA2 ENPEP

6.82e-051371385265a4a50e48b13c8b3b0730f818235f71fbd6baa
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ADGRG4 SLC22A2 CNTNAP2 EXOG MVB12B

1.01e-0414913854b44108c40376a6b73258df40d2424e68f991383
ToppCellprimary_visual_cortex-Non-neuronal-pericyte_cell-Peri-Peri_Kcnj8|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PLA2R1 SAA1 SAA2 SPON2 ENPEP

1.22e-041551385ced64e26962c5c6e6d539f361fe57ab0b399e999
ToppCellprimary_visual_cortex-Non-neuronal-pericyte_cell|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PLA2R1 SAA1 SAA2 SPON2 ENPEP

1.22e-0415513850f24ef6486aef354f0911c06932cb01d1a0525ac
ToppCellprimary_visual_cortex-Non-neuronal-pericyte_cell-Peri|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PLA2R1 SAA1 SAA2 SPON2 ENPEP

1.22e-041551385d8b5145258f075b15080f8739f537f48dd22225e
ToppCell10x5'-GI_large-bowel-Lymphocytic_T_CD4-Teffector/EM_CD4|GI_large-bowel / Manually curated celltypes from each tissue

PIAS2 FAAH2 ZNF197 CD40LG DEPDC5

1.26e-04156138501f2c0c6a936dfb59bc727feef428a906ad2a80b
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ASPHD1 TEK TIE1 CPNE1 TRPV3

1.29e-0415713852c946c6ab284fac3c25db688ed0aabe5a3f9ffa5
ToppCellHippocampus-Endothelial-MURAL|Hippocampus / BrainAtlas - Mouse McCarroll V32

PLA2R1 SAA1 SAA2 AOC3 ENPEP

1.33e-0415813852d73b5e59c650c603fec6223b1c51f0962f7bc81
ToppCellHippocampus-Endothelial-MURAL-M1(Rgs5Acta2)|Hippocampus / BrainAtlas - Mouse McCarroll V32

PLA2R1 SAA1 SAA2 AOC3 ENPEP

1.33e-0415813857f4a644534b78f7e7539cae1fd895dad6f96862b
ToppCellIPF-Epithelial-Ionocyte|IPF / Disease state, Lineage and Cell class

FAT3 SLC6A9 KCNH1 FGF13 PLCB4

1.41e-041601385d65d19f4fae60836bfd4303a1bb7de34e9d83e35
ToppCellGlobus_pallidus-Neuronal-Excitatory|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

WFS1 CLIC6 KCNH4 OTOF KCNH1

1.41e-041601385f843287ed57d2d5a3b3f6dfb03b6934e330e6645
ToppCellGlobus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

WFS1 CLIC6 KCNH4 OTOF KCNH1

1.46e-041611385ebcd5066e82b7760b9da6adc02d11258d1309dab
ToppCellPND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg-Treg_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GPR55 NEB IPCEF1 SLC22A2 CPNE1

1.50e-041621385adf545cf9357556e2ce7affed01c2f6a24b0581d
ToppCellfacs-Marrow-KLS-24m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IFT140 ENPP3 SLC6A9 SCAMP5 DAAM2

1.50e-041621385860ebf2390b4ad86475ad54717cbefcf61cd3b2a
DrugGentamicine sulfate [1405-41-0]; Up 200; 2.6uM; MCF7; HT_HG-U133A

ASPHD1 SYN3 NEB CFLAR RABGAP1L CNTNAP2 TMEM209 LRP4 CTBS

2.65e-0619613592245_UP
DrugNitrocaramiphen hydrochloride; Down 200; 10.8uM; MCF7; HT_HG-U133A

ABCA3 PTPN18 EML3 CFLAR TMEM209 CTBS GREB1 ATL2 MVB12B

2.88e-0619813597464_DN
Drugpentylamine

MAOA AOC3 SYN2 CTBS MUTYH

1.55e-05531355CID000008060
DrugBrinzolamide [138890-62-7]; Down 200; 10.4uM; PC3; HT_HG-U133A

IFT140 WWOX MAOA PTPN18 RABGAP1L ZNF197 CNTNAP2 ATL2

2.20e-0519513586670_DN
DrugNialamide [51-12-7]; Up 200; 13.4uM; MCF7; HT_HG-U133A

IFT140 TRPV1 MAOA GREB1L PLA2R1 RABGAP1L CNTNAP2 MVB12B

2.28e-0519613583871_UP
DrugTiaprofenic acid [33005-95-7]; Down 200; 15.4uM; PC3; HT_HG-U133A

IFT140 ABCA3 NEB EML3 RUSC2 CFLAR TMEM209 LRP4

2.36e-0519713584091_DN
DrugAC1LAGWX

GABRP TRPV1 MAOA AOC3 LRP1

2.42e-05581355CID000513616
DrugHA-1077 dihydrochloride; Down 200; 10uM; PC3; HG-U133A

TRPV1 LAMP2 GREB1L SLC6A9 HOXD13 TMEM209 CTBS AP3D1

2.45e-051981358436_DN
DrugPHA-00745360 [351320-33-7]; Up 200; 1uM; PC3; HT_HG-U133A

ADGRL1 GREB1L CFLAR PLA2R1 CLN3 ARHGEF9 CD40LG LRP4

2.45e-0519813584562_UP
DrugBethanechol chloride [590-63-6]; Down 200; 20.4uM; MCF7; HT_HG-U133A

TRPV1 ARFGEF1 ADGRL1 PTPN18 PIAS2 ARHGEF9 EXOG ENPEP

2.54e-0519913585539_DN
DrugPheniramine maleate [132-20-7]; Down 200; 11.2uM; PC3; HT_HG-U133A

WWOX NEB PTPN18 RUSC2 SLC6A9 ARHGEF9 CNTNAP2 SYN2

2.54e-0519913584012_DN
Drug16 d

WWOX HOXD13 KCNH1 AOC3

2.87e-05301354CID000016401
Diseaseautism spectrum disorder (implicated_via_orthology)

ABCA3 SYN3 CNTNAP1 CNTNAP5 SCAMP5 CNTNAP2 SYN1 SYN2

4.69e-071521338DOID:0060041 (implicated_via_orthology)
Diseaseautosomal recessive intellectual developmental disorder (implicated_via_orthology)

CNTNAP1 CNTNAP5 CNTNAP2

4.93e-0681333DOID:0060308 (implicated_via_orthology)
DiseaseJeune thoracic dystrophy

IFT140 IFT172 TTC21B

1.44e-05111333C0265275
DiseaseMainzer-Saldino Disease

IFT140 IFT172

2.02e-0521332C1849437
Diseasemetalloproteinase inhibitor 4 measurement

SYN3 SYN2

2.02e-0521332EFO_0801797
DiseaseShort Rib-Polydactyly Syndrome

IFT140 IFT172 TTC21B

2.48e-05131333C0036996
DiseaseSaldino-Noonan Syndrome

IFT140 IFT172 TTC21B

3.14e-05141333C0036069
DiseaseMajewski Syndrome

IFT140 IFT172 TTC21B

3.14e-05141333C0024507
DiseaseSchizophrenia

RELN MAOA SYN3 GFRA1 BRAP SLC6A9 PANK2 PEMT STON2 CNTNAP2 LRP1 SYN1 SYN2 DAAM2

4.73e-0588313314C0036341
Diseasesecretory phospholipase A2 receptor measurement

PLA2R1 LY75

6.03e-0531332EFO_0802043
DiseaseAutosomal Dominant Lateral Temporal Lobe Epilepsy

RELN DEPDC5

6.03e-0531332C1838062
Diseaseepilepsy (implicated_via_orthology)

WWOX SCAMP5 KCNH1 LRP1 SYN2 DEPDC5

9.96e-051631336DOID:1826 (implicated_via_orthology)
Diseaserenal agenesis (is_implicated_in)

GFRA1 GREB1L

1.20e-0441332DOID:14766 (is_implicated_in)
DiseasePolydactyly

IFT140 IFT172 HOXD13 TTC21B LRP4

1.93e-041171335C0152427
Diseaseserum amyloid A protein measurement

SAA1 SAA2

2.99e-0461332EFO_0004728
DiseasePolysyndactyly

HOXD13 LRP4

4.17e-0471332C0265553
DiseaseSyndactyly

HOXD13 LRP4

5.55e-0481332C0039075
Diseaseserum IgG glycosylation measurement

DNAH10 MDGA2 TEK GFRA1 CNTNAP5 TENM3 CNTNAP2 ENPEP C13orf42

6.30e-045231339EFO_0005193
Diseasecystic kidney disease (implicated_via_orthology)

IFT172 TTC21B

8.86e-04101332DOID:2975 (implicated_via_orthology)
Diseasealpha wave measurement, electroencephalogram measurement

DNAH1 TNS3

8.86e-04101332EFO_0004357, EFO_0006870
DiseaseAnilide use measurement

RABGAP1L LRP1

2.04e-03151332EFO_0009938
Diseaseautism spectrum disorder (is_implicated_in)

MAOA CNTNAP2

2.32e-03161332DOID:0060041 (is_implicated_in)
Diseasemigraine without aura, susceptibility to, 4

GFRA1 LRP1

2.32e-03161332MONDO_0011847
Diseasesuccinylcarnitine measurement

ABCC1 SYN3

2.32e-03161332EFO_0020020
Diseasecreatine kinase measurement

NEB CPNE1 ROS1

2.42e-03591333EFO_0004534
DiseaseHuntington Disease

RELN MAOA

2.62e-03171332C0020179
Diseaseresponse to opioid

CLIC6 TEK MVB12B

2.66e-03611333EFO_0008541
Diseaseserum amyloid A-1 protein measurement

SAA1 SAA2

2.94e-03181332EFO_0008282
DiseaseNuclear non-senile cataract

WFS1 FYCO1

2.94e-03181332C1112705
DiseaseNuclear cataract

WFS1 FYCO1

2.94e-03181332C0392557
Diseasegluteofemoral adipose tissue measurement

DNAH10 PEMT FGF13 EXOG

3.05e-031321334EFO_0803317
DiseaseGlobal developmental delay

GTF3C3 STT3A SCAMP5 CCDC47

3.14e-031331334C0557874
DiseaseSeizures

GALC GTF3C3 SCAMP5 SYN2 AP3D1

3.14e-032181335C0036572
Diseasecarotid artery disease (is_marker_for)

CD40LG PAPPA

3.28e-03191332DOID:3407 (is_marker_for)
DiseaseEpstein-Barr virus infection

GALC WWOX ARSI

3.33e-03661333EFO_0000769
Diseasecoronary artery disease (is_marker_for)

TEK CD40LG PAPPA

3.47e-03671333DOID:3393 (is_marker_for)
Diseasemyeloid white cell count

UBR2 DNAH10 GRAMD1A PLA2R1 BRD3OS SCAMP5 RABGAP1L SYN2 SSH2 LY75 TNS3

3.51e-0393713311EFO_0007988
Diseasebrain age measurement

GALC ECE2

3.63e-03201332EFO_0010602
Diseaseage-related macular degeneration, COVID-19

SYN3 BRAP CPNE1

3.78e-03691333EFO_0001365, MONDO_0100096
Diseasestroke, coronary artery disease

BRAP PEMT

4.00e-03211332EFO_0000712, EFO_0001645
DiseaseNeutropenia

HOXD13 AP3D1

4.00e-03211332C0027947
Diseasedisease

MDGA2 SLC22A2

4.00e-03211332EFO_0000408
Diseasetriglyceride measurement, phospholipid measurement

DNAH10 DNAH1 PEMT SLC22A2

4.38e-031461334EFO_0004530, EFO_0004639
DiseaseHodgkin Disease

RELN CFLAR

4.39e-03221332C0019829

Protein segments in the cluster

PeptideGeneStartEntry
QKESRSVYQLQYMSW

PTPN18

181

Q99952
SVYQLQYMSWPDRGV

PTPN18

186

Q99952
ALNYEMAWKYSNRTN

TTC21B

1251

Q7Z4L5
MAWKYSNRTNPAVGY

TTC21B

1256

Q7Z4L5
YAMQLTNHRVWDYAG

BRAP

356

Q7Z569
SGMVSAYNLNRAFTW

ARSH

71

Q5FYA8
LSNYYSRLEGWMMDN

LINC00596

6

Q86U02
WVTRYMLLYGDRVDS

CNTNAP1

96

P78357
SVLQWAEKGYYTMSN

CD40LG

136

P29965
SRSRSMWYSQYGNEA

BRD3OS

46

A0A1B0GUI7
MWYSQYGNEAILVRD

BRD3OS

51

A0A1B0GUI7
DNSRYWMAFSYITNN

ADGRG4

66

Q8IZF6
WGLSGQYSTMLYAQR

ARSI

201

Q5FYB1
YRLESTLNYGMERVW

COPB2

261

P35606
NYSERSMLGYWSTQG

ADGRL1

806

O94910
YYTGTQSRIRRMWND

ADGRL1

1141

O94910
EISYYNMGRIRLQWS

ARFGEF1

1171

Q9Y6D6
AWMYSRTQDCLQYLQ

C13orf42

76

A0A1B0GVH6
FSYTRRNYMWTQTGS

ABCA3

156

Q99758
YYWITGRIDDMLNVS

ACSS2

561

Q9NR19
DWVILNLNMTGYYRV

LVRN

646

Q6Q4G3
TYIQNYRLRGIGMWN

CTBS

341

Q01459
MTGIWRYLNNAYARD

CLIC6

666

Q96NY7
LNGYMYDWNSRVSAK

CFLAR

446

O15519
QSWYSMLSPTYKQRN

GRAMD1A

76

Q96CP6
SSELIYTGEMAWIYQ

ARHGEF9

316

O43307
VVRSMSTLLNYDYVW

AOC3

461

Q16853
KLTYLQMLGYDISWA

AP3D1

61

O14617
YLDYNNLWRTIDNMG

MAOA

121

P21397
TSWPDYYIDRINSMA

DAAM2

96

Q86T65
EERVGYNWAYNTMLT

DEPDC5

1541

O75140
DINTFSMRVREWYGY

NOP56

181

O00567
VLYSNMLGEENTYLW

SLC25A3

146

Q00325
MLGEENTYLWRTSLY

SLC25A3

151

Q00325
EVWMNTSEIIIYNGY

LIPN

31

Q5VXI9
KTMTSTEQSLYYRQW

GREB1

1301

Q4ZG55
MNTKVTSDWYYARSP

FYCO1

126

Q9BQS8
YREQMIYWTDVTTQG

LRP1

3066

Q07954
FLWYCYRLGSQDMQA

ASPHD1

91

Q5U4P2
IEWMRQMYYSGSLEA

MFI

181

Q8NCR3
RMSQGISSYLAWYQQ

IGKV1D-8

46

A0A087WSZ0
NSWESYYLEILMVTG

CCDC47

131

Q96A33
RDQWSMTPQTVNAYY

ECE2

596

P0DPD6
MDLSWESRTGDQYSY

LCOR

261

Q96JN0
QSNLMYWAVDRCYTG

FRYL

1166

O94915
NSWLYQLAMDIGTPY

KCNH1

416

O95259
RMLEYFQTTWAVNSG

KCNH4

511

Q9UQ05
DAEMTGYVVTRWYRA

MAPK13

176

O15264
SLPRSYTMDDAWKYN

LMO7

926

Q8WWI1
NYMASWVMLGITYRN

LY75

1306

O60449
NNLSYWDAPLGSSYM

LAMP2

316

P13473
NSGYWNRIEMYCREL

EXOG

171

Q9Y2C4
VYRYGMQNSGNEISW

ENPEP

786

Q07075
MDLNLGSVYQYWVIT

PAPPA

911

Q13219
NRWPDYAATSIYMIN

GPR55

51

Q9Y2T6
MSSEEQSLYYRQWTL

GREB1L

1276

Q9C091
IMAAVVIQSYWRGYL

LRRIQ1

1336

Q96JM4
YSYSLQWTQMNPDAV

MDGA2

651

Q7Z553
YTFIGELNSMGIWYR

MVB12B

176

Q9H7P6
KSYDGRAYVITGMWN

RABGAP1L

356

Q5R372
SSTYYAGTMQGWRRE

RELN

2076

P78509
RSYYQWLMDTQQEER

IFT172

741

Q9UG01
TVNMYRASGLWEEAY

IFT172

1061

Q9UG01
NILDNPMYWGSTANY

PEMT

136

Q9UBM1
YSTTWSEAQQYLMDN

PRPF40A

546

O75400
MRLLAYALDYWSKGQ

PANK2

531

Q9BZ23
YTFTSYAMNWVRQAP

IGHV7-4-1

46

A0A0J9YVY3
SSLRDMSKGWYNLYE

DNAH1

571

Q9P2D7
FYRAQVGSWNMLESA

IL37

156

Q9NZH6
GSSLYWYSNQMAEKA

IPCEF1

71

Q8WWN9
YNPRTNEWTYVAKMS

KLHL13

461

Q9P2N7
RIYWSMYQSLQGNDL

GFRA1

101

P56159
AEYLYTWDTLMPNIN

ENPP3

171

O14638
LDRETMGSYWLTVYA

FAT3

1106

Q8TDW7
EAYISMEGYQSWTLA

HOXD13

221

P35453
RYMYNKDSQSWIGGN

ATL2

116

Q8NHH9
MWYESSNKIYGRSNN

FAAH2

181

Q6GMR7
WVYTVQESMRAYAAN

MAN2B2

41

Q9Y2E5
SSMIYRQQQSGRGWY

FGF13

156

Q92913
QGRYSSSDWVTQYRM

CNTNAP2

101

Q9UHC6
TQYRMLYSDTGRNWK

CNTNAP2

111

Q9UHC6
IMSNSGDYEILYWDV

EML3

741

Q32P44
IMSNSGDYEILYWDI

EML4

736

Q9HC35
YMEALALVGAWYTAR

HSDL1

21

Q3SXM5
YINGYMTSTIAWNLV

GALC

296

P54803
IGYYTQAARDMWAHL

DNAH10

4166

Q8IVF4
YYLWMLNSVTLAVNL

SCAMP5

41

Q8TAC9
LMYNWFTSSVLYQGL

SLC22A2

351

O15244
IYIMAANYLQSLDWR

IFT140

1246

Q96RY7
TVWYKMQSVSVYTNG

PKD1L1

501

Q8TDX9
YSLMFSDTGRNWKQY

CNTNAP5

106

Q8WYK1
YLMALWSVGSVVQDY

CPNE1

316

Q99829
DYTATIYLRQRWMDQ

GABRP

81

O00591
WVNMYGSTRNYTLLD

OTOF

536

Q9HC10
WASEIGKNYSMSVYL

PIAS2

281

O75928
YSLQVTTYLNWLVRM

ABCC1

1236

P33527
WYQLMQSSQVYIDGS

RUSC2

1271

Q8N2Y8
GNMTYKWNTRIETYY

TAS2R41

166

P59536
QNYKAYMRTSVSGNW

SYN1

321

P17600
NNYKAYMRTSISGNW

SYN2

321

Q92777
NYKAYMRTSISGNWK

SYN3

301

O14994
MYFPSWLSQLYRGLS

DARS2

1

Q6PI48
KTSDWYMNGNYLVIL

SLC38A3

181

Q99624
YSMWRKNQYVSNGLR

SPON2

81

Q9BUD6
QAWMASYKYVGATTN

PLCB4

546

Q15147
WRAYSDMREANYIGS

SAA2

36

P0DJI9
KYQANSGTAMWFRTY

HID1

746

Q8IV36
WDYGYQITAMANRTI

STT3A

526

P46977
QTQVATVINYYTGWM

MUTYH

136

Q9UIF7
MQAYGQSSYSTQTWV

TNS3

576

Q68CZ2
YGNRTYKIINANMTW

PLA2R1

1121

Q13018
AHYSYQVALGSIWLM

STON2

866

Q8WXE9
WRAYSDMREANYIGS

SAA1

36

P0DJI8
VRYLWERSSLYEQMG

GTF3C3

251

Q9Y5Q9
WYQMLYQAGVFASRS

CLN3

321

Q13286
LKGSSLYWYSNQMAE

CNK3/IPCEF1

531

G9CGD6
DRYMDAWNTVSRAYN

TIMM13

71

Q9Y5L4
LYWDVMLENYGNVTS

ZNF197

241

O14709
TRLWNKYMSNTYEQL

USP4

181

Q13107
EGTQWSLMYYLQRLR

UNC80

346

Q8N2C7
QNYWNMVSLGLTVYR

ZNF287

201

Q9HBT7
WYRKTQGNTMTFIYR

TRDV2

56

A0JD36
MESISNNLWKYNRYR

TRPM6

1076

Q9BX84
RWLYMDSNYLDTLSR

SLITRK1

426

Q96PX8
STVIAYAMKEYGWNL

SSH2

401

Q76I76
ALGWTNMLYYTRGFQ

TRPV1

546

Q8NER1
MSRYSYQSLLDWLYG

TMEM164

1

Q5U3C3
PVRWMAIESLNYSVY

TIE1

1016

P35590
SPTKNDYWAMLAYNR

WWOX

281

Q9NZC7
TSQAGIYWLLLMDNY

SLC6A9

516

P48067
RSLMYWITIQYDNMG

TENM3

2096

Q9P273
LLTDLYQATMALGYW

NAPRT

16

Q6XQN6
YQATMALGYWRAGRA

NAPRT

21

Q6XQN6
NALMYYSGRLFWING

ROS1

886

P08922
TMQQYNICVYRWLSE

SLAMF9

121

Q96A28
PVRWMAIESLNYSVY

TEK

1001

Q02763
LPMLIRSYANGNWIY

SUCNR1

76

Q9BXA5
TFWNYSRSMGDYAQT

TMEM209

271

Q96SK2
ALGWANMLYYTRGFQ

TRPV3

556

Q8NET8
YRNSEGQFFSSMTLW

ZBTB49

736

Q6ZSB9
ILRYMWGTDTYRESI

UBE4A

751

Q14139
MWRRNGFSLVNQIYY

UBR2

666

Q8IWV8
FTWEGLYNVLMYRLS

USP11

626

P51784
MAQWLAYSRLYQSLE

UNC13D

351

Q70J99
AIMLQSGRAEYYQWV

XKR8

151

Q9H6D3
GMKVYNSTLTWQQYG

WFS1

656

O76024
SDYRVENSMYIINPW

LEG1

41

Q6P5S2
NGLTIDYAGRRMYWV

LRP4

601

O75096
YKENYMSQLGIWRSI

NEB

5301

P20929