Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionsemaphorin receptor activity

PLXNA3 PLXNA4 PLXNA1

6.77e-0612643GO:0017154
GeneOntologyMolecularFunctionaspartate:glutamate, proton antiporter activity

SLC25A12 SLC25A13

1.01e-052642GO:0000515
GeneOntologyMolecularFunction3-sulfino-L-alanine: proton, glutamate antiporter activity

SLC25A12 SLC25A13

1.01e-052642GO:0000514
GeneOntologyMolecularFunctionbent DNA binding

HMGB1 SNAPC3

3.03e-053642GO:0003681
GeneOntologyMolecularFunctionamino acid:monoatomic cation antiporter activity

SLC25A12 SLC25A13

1.01e-045642GO:0140848
GeneOntologyMolecularFunctionchemokine binding

CXCR4 HMGB1 ITGA4

1.60e-0433643GO:0019956
GeneOntologyMolecularFunctionligase activity, forming carbon-oxygen bonds

IARS1 QARS1 WARS2

3.30e-0442643GO:0016875
GeneOntologyMolecularFunctionaminoacyl-tRNA ligase activity

IARS1 QARS1 WARS2

3.30e-0442643GO:0004812
GeneOntologyMolecularFunctionL-aspartate transmembrane transporter activity

SLC25A12 SLC25A13

4.48e-0410642GO:0015183
GeneOntologyMolecularFunctionmetallopeptidase activity

BMP1 RNPEP ERAP1 IDE MMP2

4.53e-04200645GO:0008237
GeneOntologyMolecularFunctionsulfur amino acid transmembrane transporter activity

SLC25A12 SLC25A13

5.46e-0411642GO:0000099
GeneOntologyMolecularFunctionpalmitoyl-(protein) hydrolase activity

ABHD17A ABHD17B

7.71e-0413642GO:0008474
GeneOntologyMolecularFunctionpalmitoyl hydrolase activity

ABHD17A ABHD17B

8.98e-0414642GO:0098599
GeneOntologyMolecularFunctionantiporter activity

SLC9C1 SLC25A12 SLC25A13 SLC44A2

1.01e-03138644GO:0015297
GeneOntologyMolecularFunctionC4-dicarboxylate transmembrane transporter activity

SLC25A12 SLC25A13

1.03e-0315642GO:0015556
GeneOntologyMolecularFunctionL-glutamate transmembrane transporter activity

SLC25A12 SLC25A13

1.03e-0315642GO:0005313
GeneOntologyMolecularFunctionacidic amino acid transmembrane transporter activity

SLC25A12 SLC25A13

1.85e-0320642GO:0015172
GeneOntologyMolecularFunctionligase activity

IARS1 GART QARS1 WARS2

2.36e-03174644GO:0016874
GeneOntologyMolecularFunctionvirus receptor activity

MRC1 CXCR4 IDE

2.57e-0385643GO:0001618
GeneOntologyMolecularFunctionexogenous protein binding

MRC1 CXCR4 IDE

2.66e-0386643GO:0140272
GeneOntologyMolecularFunctionmetalloaminopeptidase activity

RNPEP ERAP1

3.13e-0326642GO:0070006
GeneOntologyMolecularFunctionpeptide binding

RNPEP ERAP1 HMGB1 IDE OPRL1

3.51e-03318645GO:0042277
GeneOntologyMolecularFunctiondicarboxylic acid transmembrane transporter activity

SLC25A12 SLC25A13

4.43e-0331642GO:0005310
GeneOntologyMolecularFunctionmodified amino acid transmembrane transporter activity

SLC25A12 SLC25A13

5.01e-0333642GO:0072349
GeneOntologyBiologicalProcessolfactory nerve formation

PLXNA3 PLXNA1

8.89e-062622GO:0021628
GeneOntologyBiologicalProcessadenine metabolic process

HPRT1 GART

2.66e-053622GO:0046083
GeneOntologyBiologicalProcessolfactory nerve morphogenesis

PLXNA3 PLXNA1

2.66e-053622GO:0021627
GeneOntologyBiologicalProcessdevelopmental cell growth

AKAP6 PLXNA3 MAP2 CXCR4 PLXNA4 ITGA4 PLXNA1

3.25e-05301627GO:0048588
GeneOntologyBiologicalProcessneuron projection extension

PLXNA3 MAP2 CXCR4 PLXNA4 ITGA4 PLXNA1

3.66e-05207626GO:1990138
GeneOntologyBiologicalProcessamino acid metabolic process

SLC25A12 IARS1 SLC25A13 GART QARS1 WARS2 CRTAP

6.05e-05332627GO:0006520
GeneOntologyBiologicalProcessnegative regulation of protein localization to microtubule

ABHD17A ABHD17B

8.84e-055622GO:1902817
GeneOntologyBiologicalProcessregulation of protein localization to microtubule

ABHD17A ABHD17B

8.84e-055622GO:1902816
GeneOntologyBiologicalProcessmalate-aspartate shuttle

SLC25A12 SLC25A13

8.84e-055622GO:0043490
GeneOntologyBiologicalProcessneuron projection development

JAK2 PLXNA3 MAP2 MYO7A CXCR4 HPRT1 VPS13A PLXNA4 HMGB1 MMP2 ITGA4 PREX1 PLXNA1

9.48e-0512856213GO:0031175
GeneOntologyBiologicalProcesscranial nerve morphogenesis

PLXNA3 PLXNA4 PLXNA1

1.21e-0432623GO:0021602
GeneOntologyBiologicalProcessblood circulation

AKAP6 TBC1D8 RNPEP ERAP1 CXCR4 AGTR1 MMP2 ITGA4 OPRL1

1.29e-04648629GO:0008015
GeneOntologyBiologicalProcesstrigeminal nerve morphogenesis

PLXNA3 PLXNA4

1.32e-046622GO:0021636
GeneOntologyBiologicalProcesstrigeminal nerve structural organization

PLXNA3 PLXNA4

1.32e-046622GO:0021637
GeneOntologyBiologicalProcesssymbiont entry into host cell

MRC1 CXCR4 AGTR1 HMGB1 IDE

1.54e-04169625GO:0046718
GeneOntologyBiologicalProcessmotor neuron axon guidance

PLXNA3 CXCR4 PLXNA4

1.58e-0435623GO:0008045
GeneOntologyBiologicalProcessgonadotrophin-releasing hormone neuronal migration to the hypothalamus

PLXNA3 PLXNA1

1.85e-047622GO:0021828
GeneOntologyBiologicalProcesshypothalamic tangential migration using cell-axon interactions

PLXNA3 PLXNA1

1.85e-047622GO:0021856
GeneOntologyBiologicalProcessbranchiomotor neuron axon guidance

PLXNA3 PLXNA4

1.85e-047622GO:0021785
GeneOntologyBiologicalProcesssymbiont entry into host

MRC1 CXCR4 AGTR1 HMGB1 IDE

1.87e-04176625GO:0044409
GeneOntologyBiologicalProcesscentral nervous system neuron development

PLXNA3 HPRT1 PLXNA4 PLXNA1

2.25e-0499624GO:0021954
GeneOntologyBiologicalProcessolfactory nerve development

PLXNA3 PLXNA1

2.46e-048622GO:0021553
GeneOntologyBiologicalProcessregulation of hydrolase activity

TBC1D8 JAK2 PLXNA3 RASGRP3 AGTR1 PLXNA4 HMGB1 ST18 PREX1 PLXNA1

2.67e-048786210GO:0051336
GeneOntologyBiologicalProcesstRNA aminoacylation for protein translation

IARS1 QARS1 WARS2

2.73e-0442623GO:0006418
GeneOntologyBiologicalProcessdevelopmental growth involved in morphogenesis

PLXNA3 MAP2 CXCR4 PLXNA4 ITGA4 PLXNA1

2.74e-04299626GO:0060560
GeneOntologyBiologicalProcesshypothalamus cell migration

PLXNA3 PLXNA1

3.16e-049622GO:0021855
GeneOntologyBiologicalProcesshypothalamus gonadotrophin-releasing hormone neuron differentiation

PLXNA3 PLXNA1

3.16e-049622GO:0021886
GeneOntologyBiologicalProcesshypothalamus gonadotrophin-releasing hormone neuron development

PLXNA3 PLXNA1

3.16e-049622GO:0021888
GeneOntologyBiologicalProcesscirculatory system process

AKAP6 TBC1D8 RNPEP ERAP1 CXCR4 AGTR1 MMP2 ITGA4 OPRL1

3.23e-04733629GO:0003013
GeneOntologyBiologicalProcessnerve development

PLXNA3 PLXNA4 ITGA4 PLXNA1

3.25e-04109624GO:0021675
GeneOntologyBiologicalProcesstRNA aminoacylation

IARS1 QARS1 WARS2

3.35e-0445623GO:0043039
GeneOntologyBiologicalProcessneuron development

JAK2 PLXNA3 MAP2 MYO7A CXCR4 HPRT1 VPS13A PLXNA4 HMGB1 MMP2 ITGA4 PREX1 PLXNA1

3.42e-0414636213GO:0048666
GeneOntologyBiologicalProcessamino acid activation

IARS1 QARS1 WARS2

3.58e-0446623GO:0043038
GeneOntologyBiologicalProcessprotein depalmitoylation

ABHD17A ABHD17B

3.94e-0410622GO:0002084
GeneOntologyBiologicalProcessfacial nerve structural organization

PLXNA3 PLXNA4

3.94e-0410622GO:0021612
GeneOntologyBiologicalProcesspurine nucleobase biosynthetic process

HPRT1 GART

3.94e-0410622GO:0009113
GeneOntologyBiologicalProcessL-aspartate transmembrane transport

SLC25A12 SLC25A13

4.80e-0411622GO:0070778
GeneOntologyBiologicalProcesscranial nerve formation

PLXNA3 PLXNA1

4.80e-0411622GO:0021603
GeneOntologyBiologicalProcessregulation of GTPase activity

TBC1D8 PLXNA3 RASGRP3 PLXNA4 PREX1 PLXNA1

5.02e-04335626GO:0043087
GeneOntologyBiologicalProcesssemaphorin-plexin signaling pathway

PLXNA3 PLXNA4 PLXNA1

5.15e-0452623GO:0071526
GeneOntologyBiologicalProcesspositive regulation of angiogenesis

ERAP1 CXCR4 AGTR1 HMGB1 WARS2

5.21e-04220625GO:0045766
GeneOntologyBiologicalProcesscell growth

AKAP6 PLXNA3 MAP2 CXCR4 AGTR1 PLXNA4 ITGA4 PLXNA1

5.43e-04625628GO:0016049
GeneOntologyBiologicalProcesspositive regulation of vasculature development

ERAP1 CXCR4 AGTR1 HMGB1 WARS2

5.54e-04223625GO:1904018
GeneOntologyBiologicalProcessfacial nerve morphogenesis

PLXNA3 PLXNA4

5.75e-0412622GO:0021610
GeneOntologyBiologicalProcessfacial nerve development

PLXNA3 PLXNA4

5.75e-0412622GO:0021561
GeneOntologyBiologicalProcessbiological process involved in interaction with host

MRC1 CXCR4 AGTR1 HMGB1 IDE

6.12e-04228625GO:0051701
GeneOntologyBiologicalProcessaxon development

JAK2 PLXNA3 MAP2 CXCR4 PLXNA4 MMP2 ITGA4 PLXNA1

6.48e-04642628GO:0061564
GeneOntologyBiologicalProcesscranial nerve structural organization

PLXNA3 PLXNA4

6.79e-0413622GO:0021604
GeneOntologyBiologicalProcesstrigeminal nerve development

PLXNA3 PLXNA4

6.79e-0413622GO:0021559
GeneOntologyBiologicalProcessmacromolecule depalmitoylation

ABHD17A ABHD17B

7.90e-0414622GO:0098734
GeneOntologyBiologicalProcesspositive regulation of protein localization to endosome

ABHD17A ABHD17B

7.90e-0414622GO:1905668
GeneOntologyBiologicalProcesshypothalamus cell differentiation

PLXNA3 PLXNA1

7.90e-0414622GO:0021979
GeneOntologyBiologicalProcesspositive regulation of vascular associated smooth muscle cell proliferation

JAK2 AGTR1 MMP2

8.62e-0462623GO:1904707
GeneOntologyBiologicalProcessregulation of cell migration

JAK2 PLXNA3 SP100 CXCR4 PLXNA4 HMGB1 MMP2 ITGA4 PREX1 PLXNA1 SCAI

8.74e-0412116211GO:0030334
GeneOntologyBiologicalProcesschemotaxis

PLXNA3 CXCR4 AGTR1 PLXNA4 HMGB1 MMP2 PREX1

8.92e-04517627GO:0006935
GeneOntologyBiologicalProcessnegative regulation of cell adhesion

JAK2 PLXNA3 PLXNA4 HMGB1 MMP2 PLXNA1

9.05e-04375626GO:0007162
GeneOntologyBiologicalProcessregulation of protein localization to endosome

ABHD17A ABHD17B

9.10e-0415622GO:1905666
GeneOntologyBiologicalProcessAMP biosynthetic process

HPRT1 GART

9.10e-0415622GO:0006167
GeneOntologyBiologicalProcessIMP biosynthetic process

HPRT1 GART

9.10e-0415622GO:0006188
GeneOntologyBiologicalProcesstaxis

PLXNA3 CXCR4 AGTR1 PLXNA4 HMGB1 MMP2 PREX1

9.12e-04519627GO:0042330
GeneOntologyBiologicalProcessGMP biosynthetic process

HPRT1 GART

1.04e-0316622GO:0006177
GeneOntologyBiologicalProcesscranial nerve development

PLXNA3 PLXNA4 PLXNA1

1.08e-0367623GO:0021545
GeneOntologyBiologicalProcessregulation of axon extension involved in axon guidance

PLXNA3 PLXNA4

1.17e-0317622GO:0048841
GeneOntologyBiologicalProcesslipoprotein catabolic process

ABHD17A ABHD17B

1.17e-0317622GO:0042159
GeneOntologyBiologicalProcessregulation of binding

JAK2 SP100 MAP2 HMGB1 IDE ITGA4

1.20e-03396626GO:0051098
GeneOntologyBiologicalProcessnegative regulation of vasoconstriction

MMP2 ITGA4

1.32e-0318622GO:0045906
GeneOntologyBiologicalProcessnucleobase biosynthetic process

HPRT1 GART

1.32e-0318622GO:0046112
GeneOntologyBiologicalProcessregulation of cell motility

JAK2 PLXNA3 SP100 CXCR4 PLXNA4 HMGB1 MMP2 ITGA4 PREX1 PLXNA1 SCAI

1.37e-0312806211GO:2000145
GeneOntologyBiologicalProcessregulation of anatomical structure morphogenesis

PLXNA3 SP100 MAP2 ERAP1 CXCR4 AGTR1 PLXNA4 HMGB1 WARS2 PLXNA1

1.43e-0310906210GO:0022603
GeneOntologyBiologicalProcesspreganglionic parasympathetic fiber development

PLXNA3 PLXNA4

1.47e-0319622GO:0021783
GeneOntologyCellularComponentsemaphorin receptor complex

PLXNA3 PLXNA4 PLXNA1

7.66e-0613643GO:0002116
GeneOntologyCellularComponentgamma-delta T cell receptor complex

TRGC1 TRGC2

1.37e-046642GO:0042106
GeneOntologyCellularComponentpostsynaptic recycling endosome membrane

ABHD17A ABHD17B

1.37e-046642GO:0098944
GeneOntologyCellularComponentdynactin complex

ACTR1B ACTR1A

2.55e-048642GO:0005869
GeneOntologyCellularComponentpostsynaptic endosome membrane

ABHD17A ABHD17B

4.99e-0411642GO:0098895
GeneOntologyCellularComponentaminoacyl-tRNA synthetase multienzyme complex

IARS1 QARS1

5.97e-0412642GO:0017101
GeneOntologyCellularComponentpostsynaptic recycling endosome

ABHD17A ABHD17B

7.04e-0413642GO:0098837
GeneOntologyCellularComponentmicrotubule associated complex

ACTR1B ACTR1A MAP2 DNAH7

1.50e-03161644GO:0005875
DomainPlexin_cytopl

PLXNA3 PLXNA4 PLXNA1

2.75e-069613PF08337
DomainPlexin_cytoplasmic_RasGAP_dom

PLXNA3 PLXNA4 PLXNA1

2.75e-069613IPR013548
DomainPlexin

PLXNA3 PLXNA4 PLXNA1

2.75e-069613IPR031148
DomainArp1

ACTR1B ACTR1A

1.05e-052612IPR029909
Domainaa-tRNA-synth_I_CS

IARS1 QARS1 WARS2

2.61e-0518613IPR001412
DomainAA_TRNA_LIGASE_I

IARS1 QARS1 WARS2

3.09e-0519613PS00178
DomainIPT

PLXNA3 PLXNA4 PLXNA1

9.17e-0527613SM00429
DomainTIG

PLXNA3 PLXNA4 PLXNA1

1.40e-0431613PF01833
DomainSema

PLXNA3 PLXNA4 PLXNA1

1.40e-0431613SM00630
DomainSemap_dom

PLXNA3 PLXNA4 PLXNA1

1.40e-0431613IPR001627
DomainSema

PLXNA3 PLXNA4 PLXNA1

1.40e-0431613PF01403
DomainSEMA

PLXNA3 PLXNA4 PLXNA1

1.40e-0431613PS51004
DomainPSI

PLXNA3 PLXNA4 PLXNA1

1.54e-0432613PF01437
DomainIPT

PLXNA3 PLXNA4 PLXNA1

1.54e-0432613IPR002909
DomainPlexin_repeat

PLXNA3 PLXNA4 PLXNA1

1.54e-0432613IPR002165
DomainCXCR4/ACKR2

CXCR4 AGTR1

2.18e-047612IPR001277
DomainZINC_PROTEASE

BMP1 RNPEP ERAP1 MMP2

2.96e-0498614PS00142
DomainHMG_box_2

SP100 HMGB1

3.72e-049612PF09011
DomainHydrolase_4

ABHD17A ABHD17B

3.72e-049612IPR022742
DomainHydrolase_4

ABHD17A ABHD17B

3.72e-049612PF12146
DomainRossmann-like_a/b/a_fold

IARS1 QARS1 WARS2

3.73e-0443613IPR014729
Domain-

IARS1 QARS1 WARS2

3.73e-04436133.40.50.620
DomainPSI

PLXNA3 PLXNA4 PLXNA1

3.99e-0444613IPR016201
DomainPSI

PLXNA3 PLXNA4 PLXNA1

4.55e-0446613SM00423
DomainHAT

CRNKL1 ZFC3H1

4.64e-0410612IPR003107
DomainHAT

CRNKL1 ZFC3H1

4.64e-0410612SM00386
DomainPeptidase_M1

RNPEP ERAP1

6.78e-0412612IPR001930
DomainPeptidase_M1

RNPEP ERAP1

8.00e-0413612PF01433
Domain-

MRC1 MMP2

8.00e-04136122.10.10.10
DomainPeptidase_M1_N

RNPEP ERAP1

8.00e-0413612IPR014782
DomainFN_type2_col-bd

MRC1 MMP2

9.31e-0414612IPR000562
DomainFN2_2

MRC1 MMP2

9.31e-0414612PS51092
Domainfn2

MRC1 MMP2

9.31e-0414612PF00040
DomainFN2_1

MRC1 MMP2

9.31e-0414612PS00023
DomainFN2

MRC1 MMP2

9.31e-0414612SM00059
DomainActin_CS

ACTR1B ACTR1A

1.22e-0316612IPR004001
DomainACTINS_2

ACTR1B ACTR1A

1.38e-0317612PS00432
DomainActin/actin-like_CS

ACTR1B ACTR1A

1.55e-0318612IPR020902
DomainACTINS_ACT_LIKE

ACTR1B ACTR1A

1.73e-0319612PS01132
DomainRho_GTPase_activation_prot

PLXNA3 PLXNA4 PLXNA1

2.99e-0388613IPR008936
DomainAden_trnslctor

SLC25A12 SLC25A13

3.76e-0328612IPR002113
DomainZnMc

BMP1 MMP2

4.02e-0329612SM00235
DomainPeptidase_Metallo

BMP1 MMP2

4.02e-0329612IPR006026
DomainActin

ACTR1B ACTR1A

4.59e-0331612IPR004000
PathwayREACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION

PLXNA3 PLXNA4 PLXNA1

4.39e-069543MM15030
PathwayREACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION

PLXNA3 PLXNA4 PLXNA1

1.88e-0514543MM15029
PathwayREACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION

PLXNA3 PLXNA4 PLXNA1

1.88e-0514543M7578
PathwayREACTOME_CRMPS_IN_SEMA3A_SIGNALING

PLXNA3 PLXNA4 PLXNA1

2.34e-0515543MM15031
PathwayREACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION

PLXNA3 PLXNA4 PLXNA1

2.87e-0516543M16498
PathwayREACTOME_CRMPS_IN_SEMA3A_SIGNALING

PLXNA3 PLXNA4 PLXNA1

2.87e-0516543M8245
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SOD1_TO_RETROGRADE_AXONAL_TRANSPORT

ACTR1B ACTR1A DNAH7

1.46e-0427543M47755
PathwayKEGG_BASE_EXCISION_REPAIR

PARP4 HMGB1 HMGB1P1

3.19e-0435543M5500
PathwayKEGG_MEDICUS_REFERENCE_ANGII_AT1R_NOX2_SIGNALING_PATHWAY

AGTR1 MMP2

3.97e-048542M47780
PathwayREACTOME_MALATE_ASPARTATE_SHUTTLE

SLC25A12 SLC25A13

5.10e-049542M48269
PathwayREACTOME_MALATE_ASPARTATE_SHUTTLE

SLC25A12 SLC25A13

5.10e-049542MM17242
PathwayKEGG_AMINOACYL_TRNA_BIOSYNTHESIS

IARS1 QARS1 WARS2

5.11e-0441543M14691
PathwayREACTOME_TRNA_AMINOACYLATION

IARS1 QARS1 WARS2

5.49e-0442543M456
PathwayKEGG_MEDICUS_REFERENCE_RETROGRADE_AXONAL_TRANSPORT

ACTR1B ACTR1A DNAH7

5.88e-0443543M47669
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_RETROGRADE_AXONAL_TRANSPORT

ACTR1B ACTR1A DNAH7

6.73e-0445543M47670
PathwayREACTOME_ASPARTATE_AND_ASPARAGINE_METABOLISM

SLC25A12 SLC25A13

7.75e-0411542M27836
PathwayREACTOME_ASPARTATE_AND_ASPARAGINE_METABOLISM

SLC25A12 SLC25A13

9.27e-0412542MM15556
PathwayREACTOME_SEMAPHORIN_INTERACTIONS

PLXNA3 PLXNA4 PLXNA1

9.72e-0451543MM14967
Pubmed

Chromosome assignment of four plexin A genes (Plxna1, Plxna2, Plxna3, Plxna4) in mouse, rat, Syrian hamster and Chinese hamster.

PLXNA3 PLXNA4 PLXNA1

2.61e-08466311306810
Pubmed

PlexinA polymorphisms mediate the developmental trajectory of human corpus callosum microstructure.

PLXNA3 PLXNA4 PLXNA1

2.61e-08466325518740
Pubmed

Semaphorin-6A controls guidance of corticospinal tract axons at multiple choice points.

PLXNA3 PLXNA4 PLXNA1

2.27e-07766319063725
Pubmed

Increased proximal bifurcation of CA1 pyramidal apical dendrites in sema3A mutant mice.

PLXNA3 PLXNA4 PLXNA1

2.27e-07766319655386
Pubmed

The expression of plexins during mouse embryogenesis.

PLXNA3 PLXNA4 PLXNA1

3.63e-07866315661641
Pubmed

Integration of opposing semaphorin guidance cues in cortical axons.

PLXNA3 PLXNA4 PLXNA1

3.63e-07866322368082
Pubmed

The role of neuropilins in cell signalling.

PLXNA3 PLXNA4 PLXNA1

5.44e-07966319909241
Pubmed

Plexin A3 and plexin A4 convey semaphorin signals during facial nerve development.

PLXNA3 PLXNA4 PLXNA1

7.76e-071066318804103
Pubmed

Transient microglial absence assists postmigratory cortical neurons in proper differentiation.

MRC1 MAP2 CXCR4

1.07e-061166332242005
Pubmed

On and off retinal circuit assembly by divergent molecular mechanisms.

PLXNA3 PLXNA4 PLXNA1

1.42e-061266324179230
Pubmed

Deletion of Sema3a or plexinA1/plexinA3 causes defects in sensory afferent projections of statoacoustic ganglion neurons.

PLXNA3 PLXNA4 PLXNA1

1.42e-061266323991118
Pubmed

Functional loss of semaphorin 3C and/or semaphorin 3D and their epistatic interaction with ret are critical to Hirschsprung disease liability.

PLXNA3 PLXNA4 PLXNA1

1.42e-061266325839327
Pubmed

PLXNA1 and PLXNA3 cooperate to pattern the nasal axons that guide gonadotropin-releasing hormone neurons.

PLXNA3 PLXNA4 PLXNA1

1.42e-061266331690636
Pubmed

Transcriptome profiling reveals expression signatures of cranial neural crest cells arising from different axial levels.

PLXNA3 PLXNA4 PLXNA1

1.42e-061266328407732
Pubmed

Transmembrane semaphorin signalling controls laminar stratification in the mammalian retina.

PLXNA3 PLXNA4 PLXNA1

1.42e-061266321270798
Pubmed

Plexin signaling via off-track and rho family GTPases.

PLXNA3 PLXNA4 PLXNA1

1.84e-061366311604131
Pubmed

Semaphorin3A, Neuropilin-1, and PlexinA1 are required for lymphatic valve formation.

PLXNA3 PLXNA4 PLXNA1

1.84e-061366322723296
Pubmed

Functional assembly of accessory optic system circuitry critical for compensatory eye movements.

PLXNA3 PLXNA4 PLXNA1

1.84e-061366325959730
Pubmed

Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates.

PLXNA3 PLXNA4 PLXNA1

1.84e-061366310520995
Pubmed

A midline switch of receptor processing regulates commissural axon guidance in vertebrates.

PLXNA3 PLXNA4 PLXNA1

2.34e-061466320159958
Pubmed

Calcium-induced conformational changes of the regulatory domain of human mitochondrial aspartate/glutamate carriers.

SLC25A12 SLC25A13

3.55e-06266225410934
Pubmed

Polymorphism of Tcrb and Tcrg genes in Biozzi mice: segregation analysis of a new Tcrg haplotype with antibody responsiveness.

TRGC1 TRGC2

3.55e-0626621973682
Pubmed

T cell-specific gamma genes in C57BL/10 mice. Sequence and expression of new constant and variable region genes.

TRGC1 TRGC2

3.55e-0626623486244
Pubmed

Nociceptin/orphanin FQ receptor-driven heterologous desensitization of the major HIV-1 co-receptor CXCR4.

CXCR4 OPRL1

3.55e-06266221656184
Pubmed

Beta-centractin: characterization and distribution of a new member of the centractin family of actin-related proteins.

ACTR1B ACTR1A

3.55e-0626627696711
Pubmed

Developmentally ordered V-J recombination in mouse T cell receptor gamma locus is not perturbed by targeted deletion of the Vgamma4 gene.

TRGC1 TRGC2

3.55e-0626629126983
Pubmed

Limited diversity of the rearranged T-cell gamma gene.

TRGC1 TRGC2

3.55e-0626623871915
Pubmed

Mapping genomic organization by field inversion and two-dimensional gel electrophoresis: application to the murine T-cell receptor gamma gene family.

TRGC1 TRGC2

3.55e-0626623375073
Pubmed

Structure, organization, and somatic rearrangement of T cell gamma genes.

TRGC1 TRGC2

3.55e-0626623917858
Pubmed

Phenotypic heterogeneity in IGHV-mutated CLL patients has prognostic impact and identifies a subset with increased sensitivity to BTK and PI3Kδ inhibition.

CXCR4 ITGA4

3.55e-06266225349153
Pubmed

Age-related changes in expression of CTL2/SLC44A2 and its isoforms in the mouse inner ear.

MYO7A SLC44A2

3.55e-06266221986210
Pubmed

Organization of the murine T-cell receptor gamma locus.

TRGC1 TRGC2

3.55e-0626628244371
Pubmed

Ca2+ Activation kinetics of the two aspartate-glutamate mitochondrial carriers, aralar and citrin: role in the heart malate-aspartate NADH shuttle.

SLC25A12 SLC25A13

3.55e-06266217213189
Pubmed

The genomic arrangement of T cell receptor variable genes is a determinant of the developmental rearrangement pattern.

TRGC1 TRGC2

3.55e-06266214691262
Pubmed

A gammaGT-AT1A receptor transgene protects renal cortical structure in AT1 receptor-deficient mice.

HPRT1 AGTR1

3.55e-06266215306694
Pubmed

CD49d is an independent prognostic marker that is associated with CXCR4 expression in CLL.

CXCR4 ITGA4

3.55e-06266221093051
Pubmed

Allelic differences in TCR gamma-chains alter gamma delta T cell antigen reactivity.

TRGC1 TRGC2

3.55e-0626628046225
Pubmed

Effect of acute lung injury on VLA-4 and CXCR4 expression in resident and circulating hematopoietic stem/progenitor cells.

CXCR4 ITGA4

3.55e-06266223018206
Pubmed

Exogenous aralar/slc25a12 can replace citrin/slc25a13 as malate aspartate shuttle component in liver.

SLC25A12 SLC25A13

3.55e-06266236967723
Pubmed

AGC1/2, the mitochondrial aspartate-glutamate carriers.

SLC25A12 SLC25A13

3.55e-06266227132995
Pubmed

Expression of the aspartate/glutamate mitochondrial carriers aralar1 and citrin during development and in adult rat tissues.

SLC25A12 SLC25A13

3.55e-06266212084073
Pubmed

Physical linkage of mouse Tcrg-V genes. II. Regulatory features of the Vg4-Vg3 intergenic region.

TRGC1 TRGC2

3.55e-0626628119740
Pubmed

VLA-4 and CXCR4 expression levels show contrasting prognostic impact (favorable and unfavorable, respectively) in acute myeloid leukemia.

CXCR4 ITGA4

3.55e-06266226155911
Pubmed

Expression of CXCR4 and MMP-2 is associated with poor prognosis in patients with osteosarcoma.

CXCR4 MMP2

3.55e-06266232314796
Pubmed

Distinct cytoplasmic domains in Plexin-A4 mediate diverse responses to semaphorin 3A in developing mammalian neurons.

PLXNA3 PLXNA4

3.55e-06266224619647
Pubmed

The gene mutated in adult-onset type II citrullinaemia encodes a putative mitochondrial carrier protein.

SLC25A12 SLC25A13

3.55e-06266210369257
Pubmed

New T-cell receptor gamma haplotypes in wild mice and evidence for limited Tcrg-V gene polymorphism.

TRGC1 TRGC2

3.55e-0626628420824
Pubmed

Conservation of Tcrg-V5 and limited allelic sequence polymorphism of the other Tcrg-V genes used by mouse tissue-specific gd-T lymphocytes.

TRGC1 TRGC2

3.55e-0626628550103
Pubmed

Allocation of paraventricular and supraoptic neurons requires Sim1 function: a role for a Sim1 downstream gene PlexinC1.

PLXNA3 PLXNA4 PLXNA1

3.59e-061666317356169
Pubmed

Expression of the semaphorins Sema 3D and Sema 3F in the developing parathyroid and thymus.

PLXNA3 PLXNA4 PLXNA1

3.59e-061666318489001
Pubmed

Plexin-A3 mediates semaphorin signaling and regulates the development of hippocampal axonal projections.

PLXNA3 PLXNA4 PLXNA1

4.35e-061766311683995
Pubmed

Semaphorin signaling facilitates cleft formation in the developing salivary gland.

PLXNA3 PLXNA4 PLXNA1

4.35e-061766317626059
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

PPP1R8 ACTR1B ACTR1A SLC9C1 MYO7A CXCR4 IARS1 HPRT1 HMGB1 QARS1 TSPYL4 HIF1AN

6.33e-061321661227173435
Pubmed

Structural Basis for Plexin Activation and Regulation.

PLXNA4 PLXNA1

1.06e-05366227397516
Pubmed

Myosin VIIA is specifically associated with calmodulin and microtubule-associated protein-2B (MAP-2B).

MAP2 MYO7A

1.06e-05366211171103
Pubmed

JAK2/STAT1-mediated HMGB1 translocation increases inflammation and cell death in a ventilator-induced lung injury model.

JAK2 HMGB1

1.06e-05366231467427
Pubmed

High Mobility Group Box Protein 1 Serves as a Potential Prognostic Marker of Lung Cancer and Promotes Its Invasion and Metastasis by Matrix Metalloproteinase-2 in a Nuclear Factor-κB-Dependent Manner.

HMGB1 MMP2

1.06e-05366229850505
Pubmed

Silibinin downregulates MMP2 expression via Jak2/STAT3 pathway and inhibits the migration and invasive potential in MDA-MB-231 cells.

JAK2 MMP2

1.06e-05366228440514
Pubmed

Mitochondrial dysfunction-mediated decline in angiogenic capacity of endothelial progenitor cells is associated with capillary rarefaction in patients with hypertension via downregulation of CXCR4/JAK2/SIRT5 signaling.

JAK2 CXCR4

1.06e-05366230904607
Pubmed

Hierarchy of molecular-pathway usage in bone marrow homing and its shift by cytokines.

CXCR4 ITGA4

1.06e-05366216141352
Pubmed

Soluble RAGE attenuates AngII-induced endothelial hyperpermeability by disrupting HMGB1-mediated crosstalk between AT1R and RAGE.

AGTR1 HMGB1

1.06e-05366231562296
Pubmed

The prognostic value of CXCR4, MMP-2 and MMP-9 in tongue squamous carcinoma.

CXCR4 MMP2

1.06e-05366231263828
Pubmed

Plexin signaling selectively regulates the stereotyped pruning of corticospinal axons from visual cortex.

PLXNA3 PLXNA4

1.06e-05366218523013
Pubmed

Distribution of neuronal KCC2a and KCC2b isoforms in mouse CNS.

MAP2 HPRT1

1.06e-05366224639001
Pubmed

HMGB1 promotes HCC progression partly by downregulating p21 via ERK/c-Myc pathway and upregulating MMP-2.

HMGB1 MMP2

1.06e-05366226499944
Pubmed

Ex vivo expansion of hematopoietic progenitor cells is associated with downregulation of alpha4 integrin- and CXCR4-mediated engraftment in NOD/SCID beta2-microglobulin-null mice.

CXCR4 ITGA4

1.06e-05366219144663
Pubmed

The angiotensin II-dependent nuclear translocation of Stat1 is mediated by the Jak2 protein motif 231YRFRR.

JAK2 AGTR1

1.06e-05366211152457
Pubmed

Non-oxidizable HMGB1 induces cardiac fibroblasts migration via CXCR4 in a CXCL12-independent manner and worsens tissue remodeling after myocardial infarction.

CXCR4 HMGB1

1.06e-05366228716707
Pubmed

Genetic polymorphism and exon changes of the constant regions of the human T-cell rearranging gene gamma.

TRGC1 TRGC2

1.06e-0536622879283
Pubmed

High CXCR4 and low VLA-4 expression predicts poor survival in adults with acute lymphoblastic leukemia.

CXCR4 ITGA4

1.06e-05366224239175
Pubmed

Novel BMP1, CRTAP, and SERPINF1 variants causing autosomal recessive osteogenesis imperfecta.

BMP1 CRTAP

1.06e-05366235703132
Pubmed

HIV-1 interaction with human mannose receptor (hMR) induces production of matrix metalloproteinase 2 (MMP-2) through hMR-mediated intracellular signaling in astrocytes.

MRC1 MMP2

1.06e-05366215955449
Pubmed

Identification of plexin family molecules in mice.

PLXNA3 PLXNA1

1.06e-0536628806646
Pubmed

Targeting AGTR1/NF-κB/CXCR4 axis by miR-155 attenuates oncogenesis in glioblastoma.

CXCR4 AGTR1

1.06e-05366232896760
Pubmed

Langerhans cells are not required for epidermal Vgamma3 T cell homeostasis and function.

TRGC1 TRGC2

1.06e-05366221486908
Pubmed

AT1A angiotensin receptors in the renal proximal tubule regulate blood pressure.

HPRT1 AGTR1

1.06e-05366221459331
Pubmed

Direct stimulation of Jak/STAT pathway by the angiotensin II AT1 receptor.

JAK2 AGTR1

1.06e-0536627746328
Pubmed

An analysis of candidate autism loci on chromosome 2q24-q33: evidence for association to the STK39 gene.

SLC25A12 ITGA4

1.06e-05366218348195
Pubmed

Repulsive and attractive semaphorins cooperate to direct the navigation of cardiac neural crest cells.

PLXNA4 PLXNA1

1.06e-05366218625214
Pubmed

RasGRP1, but not RasGRP3, is required for efficient thymic β-selection and ERK activation downstream of CXCR4.

CXCR4 RASGRP3

1.06e-05366223308188
Pubmed

C-X-C motif chemokine receptor 4 promotes tumor angiogenesis in gastric cancer via activation of JAK2/STAT3.

JAK2 CXCR4

1.06e-05366228544312
Pubmed

Differential expression of plexin-A subfamily members in the mouse nervous system.

PLXNA3 PLXNA1

1.06e-05366211241833
Pubmed

ClC-3 Deficiency Impairs the Neovascularization Capacity of Early Endothelial Progenitor Cells by Decreasing CXCR4/JAK-2 Signalling.

JAK2 CXCR4

1.06e-05366231679624
Pubmed

SDF-1/CXCR4 and VLA-4 interaction regulates homing in Waldenstrom macroglobulinemia.

CXCR4 ITGA4

1.06e-05366218448868
Pubmed

Identification of the cytoplasmic domains of CXCR4 involved in Jak2 and STAT3 phosphorylation.

JAK2 CXCR4

1.06e-05366215615703
Pubmed

Cucurbitacin I inhibits Rac1 activation in breast cancer cells by a reactive oxygen species-mediated mechanism and independently of Janus tyrosine kinase 2 and P-Rex1.

JAK2 PREX1

1.06e-05366223478800
Pubmed

Safety and efficacy profile of G-CSF therapy in patients with acute on chronic liver failure.

CXCR4 ITGA4

1.06e-05366217964871
Pubmed

Myeloid translocation gene 16b is a dual A-kinase anchoring protein that interacts selectively with plexins in a phospho-regulated manner.

PLXNA3 PLXNA1

1.06e-05366220138877
Pubmed

Differences between chronic lymphocytic leukaemia and small lymphocytic lymphoma cells by proteomic profiling and SNP microarray analysis.

CXCR4 ITGA4

1.06e-05366229153094
Pubmed

Angiotensin II type 1 receptor expression in human gastric cancer and induces MMP2 and MMP9 expression in MKN-28 cells.

AGTR1 MMP2

1.06e-05366217486447
Pubmed

A semaphorin code defines subpopulations of spinal motor neurons during mouse development.

PLXNA3 PLXNA4 PLXNA1

1.28e-052466315869472
Pubmed

A radial axis defined by semaphorin-to-neuropilin signaling controls pancreatic islet morphogenesis.

PLXNA3 PLXNA4 PLXNA1

1.28e-052466328893946
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

ACTR1A CRNKL1 RNPEP CXCR4 IARS1 HPRT1 SLC25A13 GART HMGB1 IDE QARS1 PLXNA1

1.35e-051425661230948266
Pubmed

Expression of Robo/Slit and Semaphorin/Plexin/Neuropilin family members in the developing hypothalamic paraventricular and supraoptic nuclei.

PLXNA3 PLXNA4 PLXNA1

2.07e-052866318617019
Pubmed

GRK2 mediates TCR-induced transactivation of CXCR4 and TCR-CXCR4 complex formation that drives PI3Kγ/PREX1 signaling and T cell cytokine secretion.

CXCR4 PREX1

2.12e-05466230018141
Pubmed

Slc25a13-knockout mice harbor metabolic deficits but fail to display hallmarks of adult-onset type II citrullinemia.

SLC25A12 SLC25A13

2.12e-05466214701727
Pubmed

Osteopontin enhances the expression and activity of MMP-2 via the SDF-1/CXCR4 axis in hepatocellular carcinoma cell lines.

CXCR4 MMP2

2.12e-05466221909361
Pubmed

Oral mucosal expression of HIV-1 receptors, co-receptors, and alpha-defensins: tableau of resistance or susceptibility to HIV infection?

MRC1 CXCR4

2.12e-05466216672549
Pubmed

Differential requirement for Plexin-A3 and -A4 in mediating responses of sensory and sympathetic neurons to distinct class 3 Semaphorins.

PLXNA3 PLXNA4

2.12e-05466215721238
Pubmed

Crosstalk between CXCR4/stromal derived factor-1 and VLA-4/VCAM-1 pathways regulates neutrophil retention in the bone marrow.

CXCR4 ITGA4

2.12e-05466219109194
InteractionSEMA5A interactions

PLXNA3 PLXNA4 PLXNA1

1.01e-067633int:SEMA5A
InteractionSEMA5B interactions

PLXNA3 PLXNA4 PLXNA1

1.29e-0515633int:SEMA5B
Cytoband9q21

IARS1 VPS13A

1.11e-04116629q21
Cytoband7p14

TRGC1 TRGC2

8.63e-04306627p14
GeneFamilyPlexins

PLXNA3 PLXNA4 PLXNA1

1.37e-069473683
GeneFamilyAminoacyl tRNA synthetases, Class I

IARS1 QARS1 WARS2

1.55e-0519473131
GeneFamilyZinc fingers MYND-type|A-kinase anchoring proteins

AKAP6 MAP2 MYO7A

5.74e-0529473396
GeneFamilyAminopeptidases|CD molecules

RNPEP ERAP1

8.77e-0417472104
GeneFamilyT cell receptor gamma locus at 7p14

TRGC1 TRGC2

1.48e-0322472375
GeneFamilyAbhydrolase domain containing

ABHD17A ABHD17B

1.48e-03224724
GeneFamilyEF-hand domain containing

SLC25A12 RASGRP3 SLC25A13 DNAH7

2.48e-03219474863
GeneFamilyC-type lectin domain family

MRC1 CLEC19A

6.64e-0347472494
GeneFamilyAnkyrin repeat domain containing|FERM domain containing

JAK2 MYO7A

7.48e-03504721293
GeneFamilySolute carriers

SLC9C1 SLC25A12 SLC25A13 SLC44A2

1.91e-02395474752
CoexpressionGSE9601_UNTREATED_VS_NFKB_INHIBITOR_TREATED_HCMV_INF_MONOCYTE_UP

SLC25A12 PLXNA4 CNKSR2 ITGA4 PREX1 OPRL1

3.78e-06165666M6880
CoexpressionBLANCO_MELO_HUMAN_PARAINFLUENZA_VIRUS_3_INFECTION_A594_CELLS_UP

JAK2 SP100 MAP2 ERAP1 RASGRP3 HERC5

1.27e-05204666M34006
CoexpressionMURARO_PANCREAS_ENDOTHELIAL_CELL

TBC1D8 CXCR4 RASGRP3 SLC44A2 HMGB1 MMP2 PREX1

3.50e-05362667M39176
CoexpressionCOLDREN_GEFITINIB_RESISTANCE_UP

ACTR1A IARS1 IDE CRTAP

6.67e-0586664M18134
CoexpressionOSMAN_BLADDER_CANCER_UP

TBC1D8 ABHD17A ACTR1A PARP4 ERAP1 SLC25A13 CRTAP

6.77e-05402667M5275
CoexpressionGSE3920_UNTREATED_VS_IFNB_TREATED_ENDOTHELIAL_CELL_DN

SLC25A12 SLC44A2 TSPYL4 PREX1 HERC5

8.05e-05175665M6694
CoexpressionWALLACE_PROSTATE_CANCER_RACE_UP

MRC1 ERAP1 CXCR4 RASGRP3 ITGA4 HERC5

1.15e-04303666M10319
CoexpressionLTE2_UP.V1_DN

JAK2 SP100 AGTR1 GART HERC5

1.34e-04195665M2721
CoexpressionGAO_LARGE_INTESTINE_ADULT_CA_ENTEROENDOCRINE_CELLS

AKAP6 MAP2 AGTR1 MMP2 CEP126 ST18

1.35e-04312666M39161
CoexpressionGSE10325_CD4_TCELL_VS_LUPUS_CD4_TCELL_DN

SP100 MYO7A RASGRP3 SNAPC3 HERC5

1.47e-04199665M3093
CoexpressionGSE41867_NAIVE_VS_DAY6_LCMV_EFFECTOR_CD8_TCELL_UP

ACTR1A ABHD17B MYO7A SLC44A2 ITGA4

1.51e-04200665M9455
CoexpressionGSE1432_CTRL_VS_IFNG_24H_MICROGLIA_UP

BMP2K CXCR4 HPRT1 RASGRP3 MMP2

1.51e-04200665M3407
CoexpressionGSE27786_LSK_VS_CD8_TCELL_DN

CRNKL1 CNKSR2 SNAPC3 ITGA4 TSPYL4

1.51e-04200665M4750
CoexpressionGSE27786_LIN_NEG_VS_NKTCELL_UP

PPP1R8 RNPEP CIAO3 IARS1 HPRT1

1.51e-04200665M4787
CoexpressionGSE16450_CTRL_VS_IFNA_6H_STIM_IMMATURE_NEURON_CELL_LINE_UP

JAK2 BMP2K IARS1 ZFC3H1 WARS2

1.51e-04200665M7417
CoexpressionVALK_AML_WITH_FLT3_ITD

MRC1 TRGC1 MMP2

1.52e-0441663M10010
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HNBML5

PLXNA3 MAP2 PLXNA4 CEP126 TSPYL4 ST18 SCAI

1.67e-04465667M39066
ToppCellfacs-Lung-24m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TBC1D8 JAK2 BMP2K ZFC3H1 ITGA4 PREX1

3.01e-0718565619fa853f6f746ccf232a343b3c9c7a5e55800409
ToppCellNS-moderate-d_0-4|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

AKAP6 TBC1D8 ABCA13 HS3ST6 CEP126 DNAH7

3.86e-07193656ea345d34440b25f65358a53dc72831998d1c3620
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MRC1 BMP2K CXCR4 ITGA4 ST18 PREX1

3.98e-0719465696f16bcd393a0d3f8df479b172b5360ae5a1e663
ToppCellTracheal-NucSeq-Immune_Lymphocytic-T-T_CD8-gdT|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MYO7A CXCR4 TRGC1 TRGC2 ITGA4 PREX1

4.35e-07197656b803c07072a7860497d07a3be358a28a24359cbf
ToppCell390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5|390C / Donor, Lineage, Cell class and subclass (all cells)

SP100 CXCR4 TRGC2 UGT3A2 ITGA4

2.71e-06150655fdbfc8f743cf848978cf0488493f6df60be53982
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-neuro-epithelial-N_cells_(NTS+)|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MIR7-3HG MAP2 AGTR1 PLXNA4 ST18

5.75e-0617565597a58bc6ed2e8e359283d4214172c990c6e3755e
ToppCellControl-B_cells-B_cells|Control / group, cell type (main and fine annotations)

SP100 BMP2K CXCR4 RASGRP3 ITGA4

5.91e-06176655d2c353783bd78dc24f28e00d917b88d8294fb5df
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

AKAP6 ABCA13 CEP126 CPT1B DNAH7

6.24e-061786553b12db04006db6e94fc45649a4b3a63b92f21a61
ToppCellfacs-Lung-EPCAM-24m-Myeloid-dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBC1D8 JAK2 BMP2K ITGA4 PREX1

6.42e-0617965551872338e54c5f3e42ca9f1c4cf1e8b0cb84afcc
ToppCellfacs-Lung-EPCAM-24m-Myeloid-Ccr7+_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBC1D8 JAK2 BMP2K ITGA4 PREX1

6.42e-061796551b979e0203a2ddfe98bf6c2c80c4af1ba437a80f
ToppCellILEUM-non-inflamed-(1)_T_(gd)|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

MIR7-3HG CXCR4 TRGC1 TRGC2 HMGB1

6.59e-0618065544c37644973c4fc555dc966f8cfe1f4f81fef300
ToppCellPCW_10-12-Immune_Lymphocytic-Immune_Lymphocytic_NK/ILC-im_ILC2_(21)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

CXCR4 TRGC1 TRGC2 ITGA4 PREX1

7.33e-0618465533db879e629821fb75684e60f8f0749cf9623bdd
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Immune-Myeloid-Monocytic-Monocyte-derived_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MRC1 CXCR4 ITGA4 ST18 PREX1

7.73e-06186655e152bdd837366e3e0b8bcfdb4d53f0685f2e803a
ToppCellnormal-na-Lymphocytic_B-B_naive-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

AKAP6 SP100 MAP2 CXCR4 RASGRP3

8.14e-06188655ec72ba73b10c6f2ff39699b6b46b90a3e95a4c24
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid-Monocytic-Monocyte-derived_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BMP2K CXCR4 ITGA4 ST18 PREX1

8.14e-061886550d7296ad26e97ad91c6927a6cfe4e6e70a74c5a6
ToppCellPCW_13-14-Immune_Lymphocytic-Immune_Lymphocytic_NK/ILC-im_ILC2_(21)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

CXCR4 TRGC1 TRGC2 ITGA4 PREX1

8.35e-06189655620d5a71b8cb6288540e2d2d848b9d4d66c1226f
ToppCellCOVID-19-Heart-T_cell|Heart / Disease (COVID-19 only), tissue and cell type

ABCA13 CXCR4 TRGC1 TRGC2 ITGA4

8.57e-06190655e6c3a6e01fef6c5b49f72661d4fb0414ba9046bf
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TBC1D8 ABCA13 PLPPR3 CEP126 DNAH7

8.79e-06191655683e5c7e6173644f01e67c98ab7b75d7cb9cce99
ToppCell15-Trachea-Epithelial-Intermediate_ciliated|Trachea / Age, Tissue, Lineage and Cell class

ABCA13 HS3ST6 PLPPR3 CEP126 DNAH7

9.01e-061926559cbe961a800c981cdc742a47ed18e9c8eb6430bd
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCA13 HS3ST6 PLPPR3 CEP126 DNAH7

9.24e-06193655e1b76102f812c433195d1e8811fdd3293a7bc22e
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic-Monocyte-derived_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MRC1 BMP2K ITGA4 ST18 PREX1

9.24e-061936553e3d7cb3e7242ec9c9677e07e303835649852b52
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CXCR4 TRGC1 TRGC2 ITGA4 PREX1

9.24e-0619365512f1333f11e6c262954ad7912d8fd2962ab06d25
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-lymphocytic|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CXCR4 TRGC1 TRGC2 HMGB1 ITGA4

9.24e-0619365581fdb825245cd346bf7277086b95d72a47bded73
ToppCellSmart-seq2-bone_marrow_(Smart-seq2)-lymphocytic-T_lymphocytic-CD8-positive,_alpha-beta_T_cell|bone_marrow_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CXCR4 TRGC1 TRGC2 HMGB1 ITGA4

9.48e-06194655bf2480acec5612cd8a3c33d3e7a98176dc6c9091
ToppCellControl-Epithelial-Ciliated|World / Disease state, Lineage and Cell class

SLC9C1 ABCA13 CEP126 CLEC19A DNAH7

9.48e-06194655958e648138676d46698090b4046cb484083ae449
ToppCellIIF-Lymphocyte-T_NK-CD8_TEM|IIF / Disease, Lineage and Cell Type

ABHD17A CXCR4 TRGC1 TRGC2 ITGA4

9.48e-06194655f4f7c85963ba52ee7ca2ef5657e60680fe6332fe
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

AKAP6 ABCA13 PLPPR3 CEP126 DNAH7

9.48e-061946554a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-lymphocytic-innate_lymphocytic-mature_NK_T_cell|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ABHD17A CXCR4 TRGC1 TRGC2 ITGA4

9.48e-06194655ae5357e2a276473cde1fc8c43acaf9f69da35fd7
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-lymphocytic-innate_lymphocytic|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ABHD17A CXCR4 TRGC1 TRGC2 ITGA4

9.48e-061946553a0b8b5d0354c43da57bb951cd8ba878363c3de5
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MRC1 BMP2K ITGA4 ST18 PREX1

9.72e-0619565591a3c439f10c03c5d51d904f512b6a08040edc76
ToppCellChildren_(3_yrs)-Immune-alveolar_macrophage_(MARCO_positive)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

MRC1 BMP2K RASGRP3 SLC25A13 ST18

9.72e-061956559d649ac7d2af313481069c95349efc0c68449e2b
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

CXCR4 TRGC1 TRGC2 ITGA4 PREX1

9.72e-0619565536c784709ee32174e05b457500339c3b8eee3244
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Monocytic-Monocyte-derived_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MRC1 BMP2K ITGA4 ST18 PREX1

1.02e-0519765557dafb3047745a44b2345b8036e159c3641d496e
ToppCellTracheal-10x3prime_v2-Immune_Lymphocytic-NK-ILC-T_NK-ILC|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

MYO7A CXCR4 TRGC1 TRGC2 ITGA4

1.02e-051976559791923feefbd78810242113ad2a08ce4c2bb4f2
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic-Monocyte-derived_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MRC1 BMP2K CXCR4 ITGA4 PREX1

1.02e-05197655826cc6baafab13e7ef5cfcf28cd79d0fbf3af38d
ToppCell5'-GW_trimst-1-SmallIntestine-Neuronal-neurons_A|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

AKAP6 MIR7-3HG MAP2 CXCR4 ST18

1.02e-05197655a07e1a9b95c9f8a09452cbfe5a9f06648f66e29e
ToppCellFetal_29-31_weeks-Immune|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MRC1 BMP2K CXCR4 ITGA4 PREX1

1.05e-051986555dff131356b8c22743bd27b2b21f86ee6e4a0a0d
ToppCellTracheal-NucSeq-Immune_Lymphocytic-T-T_CD8-CD8_GZMK+|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CXCR4 TRGC1 TRGC2 ITGA4 PREX1

1.07e-0519965509e0b45529fa9d5fc86da1747b3fb3a238a09aa6
ToppCellTracheal-NucSeq-Immune_Lymphocytic-T-T_CD8-CD8_TRM|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CXCR4 TRGC1 TRGC2 ITGA4 PREX1

1.07e-05199655b947ecaf912d97869f6df32736b8c2b2dd695d66
ToppCellTracheal-NucSeq-Immune_Lymphocytic-T-T_CD8-CD8|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CXCR4 TRGC1 TRGC2 ITGA4 PREX1

1.10e-052006555f41906cf1585e09b150a84364d47c3e466dc5b7
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

JAK2 SP100 ZFC3H1 ITGA4 HERC5

1.10e-0520065512f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellBronchial-NucSeq-Immune_Myeloid-Macrophage_other|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MRC1 BMP2K MYO7A RASGRP3 ST18

1.10e-0520065578d75d381cb2b9a4c9eb7c32a07b014eaee39195
ToppCellMS-IIF-Lymphocyte-T/NK-CD8+_Tem|IIF / Disease, condition lineage and cell class

ABHD17A CXCR4 TRGC1 TRGC2 ITGA4

1.10e-05200655d75582d50f178ec67490fc298d42b10e18640c5a
ToppCellTracheal-NucSeq-Immune_Lymphocytic-T-T_CD8|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CXCR4 TRGC1 TRGC2 ITGA4 PREX1

1.10e-0520065513d8c5d65d7f900979319433e7044efa6d06de20
ToppCellParenchymal-NucSeq-Immune_Lymphocytic-T-T_CD8|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CXCR4 TRGC1 TRGC2 ITGA4 PREX1

1.10e-0520065566fb892bda1d29e67a65717e85f2ec221f520b2a
ToppCellTracheal-NucSeq-Immune_Lymphocytic-T-T_CD8-CD8_CTL|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CXCR4 TRGC1 TRGC2 ITGA4 PREX1

1.10e-05200655893bb7c25ad7c6589a4c7c0364c2ace666e9b4be
ToppCellTracheal-NucSeq-Immune_Lymphocytic-T|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CXCR4 TRGC1 TRGC2 ITGA4 PREX1

1.10e-05200655dbbc7e16929e744b48017da068479a6046e99cf6
ToppCellTracheal-10x5prime-Immune_Myeloid-Macrophage_other-Macro_AW_CX3CR1|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

BMP2K MYO7A CXCR4 ITGA4 PREX1

1.10e-0520065527f498bcd706d0751091662996795b5270e46f14
ToppCellParenchymal-NucSeq-Immune_Lymphocytic-T-T_CD8-CD8_TRM|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CXCR4 TRGC1 TRGC2 ITGA4 PREX1

1.10e-052006559ef322486e46e4ff05a8cbe06cf8019e996c94b3
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|367C / Donor, Lineage, Cell class and subclass (all cells)

CXCR4 TRGC1 TRGC2 SCAI

4.05e-05131654cc5b5afab8622e98f673fa116a226d930c295327
ToppCell343B-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1|343B / Donor, Lineage, Cell class and subclass (all cells)

CXCR4 TRGC1 TRGC2 CPT1B

6.68e-051496542a7f71da51c85e04de2123164914122480e60d66
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

ABHD17A TRGC1 DNAH7 PREX1

7.04e-051516540cc2f4aec3dae4603fa831f22c40f897e68b34e2
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell-T_gdT_c14-TRDV2|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

ABHD17A TRGC1 DNAH7 PREX1

7.04e-05151654b545823113a3450c5f841f7de48bf0937593544f
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-lymphocytic-T_lymphocytic-effector_CD8-positive,_alpha-beta_T_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

BMP1 CXCR4 TRGC2 PLPPR3

7.99e-05156654b0511ce81c446482339def3a0945fcbba6da35d0
ToppCellCOVID-19-Myeloid-Dendritic_cells|COVID-19 / group, cell type (main and fine annotations)

MRC1 ITGA4 ST18 PREX1

7.99e-05156654a07a9096799e4ba663841c70035b4b32c1fda4f9
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_4|367C / Donor, Lineage, Cell class and subclass (all cells)

CXCR4 TRGC2 ZNF431 ITGA4

7.99e-0515665471f49db7d6da5533ecfcd4eacb50ecf1f30ee712
ToppCellICU-NoSEP-Lymphocyte-T_NK-gdT|ICU-NoSEP / Disease, Lineage and Cell Type

ABHD17A CXCR4 TRGC1 TRGC2

8.81e-051606542798c5bd971407f27dd4d3a4831d63d9c88003c3
ToppCell3'-GW_trimst-2-SmallIntestine-Hematopoietic-T_cells-ILCP|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CXCR4 TRGC1 TRGC2 ITGA4

9.02e-051616546d9907e2949a742c0933128fde57832a9ca5f77c
ToppCell367C-Lymphocytic-ILC-ILC-1|367C / Donor, Lineage, Cell class and subclass (all cells)

MYO7A CXCR4 TRGC1 TRGC2

9.24e-0516265474cd0de957fdbe527656befd61f67d6814ce9e98
ToppCellfacs-MAT-Fat-3m-Myeloid-nan|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBC1D8 MRC1 ITGA4 PREX1

9.69e-051646541250876abd7311f86730e5b9c03c3610cc2ff6d3
ToppCellfacs-MAT-Fat-3m-Myeloid|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBC1D8 MRC1 ITGA4 PREX1

9.69e-05164654fa0d77b648cde5e42b9394e877168c80de238bde
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Immune-Lymphocytic_T/NK-Natural_Killer_Cell_/_Natural_Killer_T_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRGC1 TRGC2 UGT3A2 ITGA4

9.69e-05164654649e42d9cfdec2f7771d1e938b516e46e7d07078
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Immune-Lymphocytic_T/NK-Natural_Killer_Cell_/_Natural_Killer_T_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRGC1 TRGC2 UGT3A2 ITGA4

9.69e-05164654ba85f7b21ae34e285d286ada24715885ca6329f7
ToppCellfacs-MAT-Fat-3m-Myeloid-macrophage|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBC1D8 MRC1 ITGA4 PREX1

9.69e-05164654b81498c3934e0d52bf0329dc745e02966f9d8613
ToppCellDendritic_Cells-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

MRC1 CXCR4 ITGA4 PREX1

1.02e-04166654fbeb74b98b58085de323f744b18d4a8f7b22d5d4
ToppCell3'-Adult-LargeIntestine-Epithelial-mature_enterocytic-Paneth|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

AKAP6 HMGB1 CLEC19A WARS2

1.02e-04166654b64ab3d13b76bba3c305ebbfc96f983cd6ca30c9
ToppCell367C-Lymphocytic-ILC-ILC-1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

MYO7A TRGC1 TRGC2 SNAPC3

1.06e-0416865480233a13135fd159f5764336a1fe67fba237776b
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Lymphocytic_T/NK-Natural_Killer_Cell_/_Natural_Killer_T_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CXCR4 TRGC1 TRGC2 ITGA4

1.06e-04168654318fa1bd5a9d6ae95042517ef30515b6416b61e4
ToppCellmetastatic_Brain-Myeloid_cells-pDCs|Myeloid_cells / Location, Cell class and cell subclass

SLC44A2 PLXNA4 CEP126 TSPYL4

1.06e-041686544bf3f85aac4b335efa93d22c9ce7b153cb5ce152
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Lymphocytic_T/NK-Natural_Killer_Cell_/_Natural_Killer_T_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CXCR4 TRGC1 TRGC2 ITGA4

1.06e-0416865475b3998aff704a77895ee3723813d8a3819b7cec
ToppCellcontrol-Myeloid-pDC|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

VPS13A SLC44A2 PLXNA4 CEP126

1.06e-04168654affc39c7568b7df4b36af6f5b0e3702a18b6268c
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-CD8_NK_sig-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CXCR4 TRGC1 TRGC2 ITGA4

1.09e-04169654f06118754fa62c580b4bcbecff6f9e5fdc2106a0
ToppCelldroplet-Marrow-nan-3m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MRC1 SP100 BMP2K TSPYL4

1.09e-041696545f5bec13208f4c3b6eacbba180c8a6402743b76e
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAP2 ZNF431 PLXNA1 SCAI

1.09e-04169654cd16e8462ee09877be962fbd9a3badcb825820b0
ToppCell3'-Child09-12-SmallIntestine-Epithelial-neuro-epithelial-N_cells_(NTS+)|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MIR7-3HG SLC9C1 CEP126 ST18

1.11e-0417065402f0be0aab8ba2d35a83238609352ef3677511c9
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic-Monocyte-derived_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MRC1 ITGA4 ST18 PREX1

1.16e-0417265472fbfa890995e47048b47199c170cc7dcd7661f8
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MRC1 ITGA4 ST18 PREX1

1.16e-041726542ca6f0d1181aabe0d0e3e8f2e193f08dbda42dea
ToppCellURO-Lymphocyte-T_NK-gdT|URO / Disease, Lineage and Cell Type

CXCR4 TRGC1 TRGC2 HMGB1

1.16e-0417265497b1eb95234639fcaa5ea3c4ba7ec2f4eb929dbf
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCA13 CEP126 CLEC19A DNAH7

1.19e-04173654c3762655caa79ac4879876f470d32578a3c93b01
ToppCellfacs-Trachea-nan-3m-Myeloid-macrophage|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MRC1 BMP2K CXCR4 ITGA4

1.19e-041736544e9b6c71030ae0d63d54e7255e4a10b25970fcc4
ToppCelldroplet-Lung-LUNG-1m-Myeloid-Ccr7+_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBC1D8 BMP2K PLXNA4 ZFC3H1

1.22e-041746547be0c6248e77f2d0260b852b01e17892f7828f1b
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Immune-Lymphocytic_T/NK-T_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CXCR4 TRGC1 TRGC2 ITGA4

1.22e-0417465447e308a777c927ae69ed344cb3dd8561bf2c48a5
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Immune-Lymphocytic_T/NK-T_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CXCR4 TRGC1 TRGC2 ITGA4

1.22e-04174654a92c745d20633909db0f08effa13fc738fda79a6
ToppCelldroplet-Lung-1m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TBC1D8 BMP2K PLXNA4 ZFC3H1

1.24e-041756541b910c08d2bfbcc77431ee66103e63a11a9d39fe
ToppCell356C-Lymphocytic-ILC|356C / Donor, Lineage, Cell class and subclass (all cells)

MYO7A CXCR4 TRGC1 TRGC2

1.24e-041756547fa8330ce813c48bd332be618909e5ec8d0f5d7e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK-Natural_Killer_Cell_/_Natural_Killer_T_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRGC1 TRGC2 ITGA4 PREX1

1.24e-041756542f43883d7c89f09b0579a390a7431f1f9b832582
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK-Natural_Killer_Cell_/_Natural_Killer_T_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRGC1 TRGC2 ITGA4 PREX1

1.24e-04175654da92eb8af0c7c65fed4a1d960708240f35dd997d
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-T_cells-NK_T_cell|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ABHD17A TRGC1 TRGC2 PREX1

1.27e-04176654dbc4f64cd39b229f2355ca1d0215cc7f6a767dce
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

AKAP6 ABCA13 CEP126 DNAH7

1.27e-04176654dee780cfa85234a7cd7bf440b66b84cec959893e
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1|356C / Donor, Lineage, Cell class and subclass (all cells)

CXCR4 TRGC1 TRGC2 ITGA4

1.27e-041766549399e174d14e81cc977fcb48facf844ee6726603
ToppCell5'-GW_trimst-2-SmallIntestine-Hematopoietic-T_cells-ILCP|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CXCR4 TRGC1 TRGC2 PREX1

1.27e-04176654238244294d08975df6bfa26b2b437db3654408ae
ToppCellCOVID-19_Severe-CD4+_CTL|COVID-19_Severe / disease group, cell group and cell class

ABHD17A CXCR4 TRGC1 TRGC2

1.30e-0417765434e9455790bae905dd91923792f4109d18b7686e
ToppCell3'_v3|World / Manually curated celltypes from each tissue

ABHD17A MRC1 TRGC2 HMGB1

1.33e-0417865442502f14d9c756df8104900ac6484477b885d3d9
ToppCellIIF-Lymphocyte-T_NK-gdT|IIF / Disease, Lineage and Cell Type

ABHD17A CXCR4 TRGC1 TRGC2

1.33e-041786543344d1328fd9c570c3a4b2629edec627a442d0e0
ToppCell356C-Lymphocytic-ILC-ILC-1|356C / Donor, Lineage, Cell class and subclass (all cells)

MYO7A CXCR4 TRGC1 TRGC2

1.33e-0417865440df4bb0978e5e5568c52ad4a5881ea0cdc6941d
ToppCell3'-Adult-LargeIntestine-Epithelial-neuro-epithelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MIR7-3HG MAP2 CEP126 ST18

1.36e-04179654f93e81a3fd94adedb24a9db4ac1d53e275bbf8b5
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Immune-Lymphocytic_T/NK|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CXCR4 TRGC1 TRGC2 ITGA4

1.36e-04179654874a9afa91774221c9c1775aa4968ba0aea7b554
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-lymphocytic-T_lymphocytic-naive_thymus-derived_CD8-positive,_alpha-beta_T_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ABHD17A CXCR4 TRGC2 HMGB1

1.36e-04179654c1f7c1b73dc1cb2135da390b16d3b5bd645cd724
ToppCell3'-GW_trimst-1-LargeIntestine-Hematopoietic-T_cells-ILCP|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CXCR4 TRGC1 TRGC2 PREX1

1.36e-04179654dd3cf8fd10dc257d933a7f45860dc2e244c158b7
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TBC1D8 ABCA13 CEP126 DNAH7

1.39e-041806541f1af4474f3f0ac3c0d6b1a6c875c354d36d8eec
ComputationalGenes in the cancer module 371.

BMP1 HMGB1 MMP2

1.45e-0426433MODULE_371
DrugFormyl

ACTR1B ACTR1A CXCR4 CIAO3 GART HMGB1 MMP2 ITGA4

3.83e-07238658CID000123370
Drugarabinosyladenine

AKAP6 ACTR1B ACTR1A CXCR4 IARS1 HPRT1 GART MMP2 QARS1 WARS2 OPRL1

9.46e-067626511CID000000191
DrugFumadil B

RNPEP MAP2 ERAP1 PLXNA1

1.72e-0554654CID000003430
Drugchlorpromazine hydrochloride; Up 200; 1uM; MCF7; HT_HG-U133A_EA

BMP1 MAP2 BMP2K CXCR4 AGTR1 VPS13A

1.87e-05193656997_UP
DrugBetulin [473-98-3]; Down 200; 9uM; MCF7; HT_HG-U133A

JAK2 BMP2K CXCR4 MMP2 SNAPC3 PLXNA1

1.98e-051956563513_DN
DrugKanamycin A sulfate [25389-94-0]; Down 200; 6.8uM; PC3; HT_HG-U133A

JAK2 BMP1 SP100 BMP2K VPS13A MMP2

2.29e-052006564625_DN
DrugAp3U

QARS1 WARS2

2.40e-053652CID003082313
Diseasecommon bile duct disease (implicated_via_orthology)

SLC25A12 SLC25A13

4.78e-062652DOID:4137 (implicated_via_orthology)
Diseaseatherosclerosis (biomarker_via_orthology)

JAK2 HMGB1 MMP2

1.13e-0520653DOID:1936 (biomarker_via_orthology)
Diseasecitrullinemia (implicated_via_orthology)

SLC25A12 SLC25A13

1.43e-053652DOID:9273 (implicated_via_orthology)
Diseaseblood rubidium measurement

ABCA13 PREX1 HIF1AN

2.56e-0526653EFO_0021529
Diseaseintrahepatic cholestasis (implicated_via_orthology)

SLC25A12 SLC25A13

2.86e-054652DOID:1852 (implicated_via_orthology)
Diseasecongestive heart failure (implicated_via_orthology)

CXCR4 AGTR1 HMGB1

1.02e-0441653DOID:6000 (implicated_via_orthology)
Diseaseneuroimaging measurement

MRC1 ACTR1B ACTR1A MAP2 CXCR4 RASGRP3 CNKSR2 HIF1AN WARS2 SCAI

1.09e-0410696510EFO_0004346
Diseasenephritis (implicated_via_orthology)

AGTR1 ITGA4

2.13e-0410652DOID:10952 (implicated_via_orthology)
DiseaseOsteogenesis imperfecta type III (disorder)

BMP1 CRTAP

2.59e-0411652C0268362
Diseasefocal segmental glomerulosclerosis (biomarker_via_orthology)

AGTR1 MMP2

3.11e-0412652DOID:1312 (biomarker_via_orthology)
Diseasemyocardial infarction (implicated_via_orthology)

JAK2 HMGB1 MMP2

4.23e-0466653DOID:5844 (implicated_via_orthology)
DiseaseNeuralgia, Supraorbital

CXCR4 HMGB1

5.62e-0416652C0038870
DiseaseNeuralgia, Iliohypogastric Nerve

CXCR4 HMGB1

5.62e-0416652C0423712
DiseaseNeuralgia, Perineal

CXCR4 HMGB1

5.62e-0416652C0423711
DiseaseNeuralgia

CXCR4 HMGB1

5.62e-0416652C0027796
DiseaseNeuralgia, Atypical

CXCR4 HMGB1

5.62e-0416652C0234247
DiseaseNeuralgia, Stump

CXCR4 HMGB1

5.62e-0416652C0234249
DiseaseParoxysmal Nerve Pain

CXCR4 HMGB1

5.62e-0416652C0751373
DiseaseNerve Pain

CXCR4 HMGB1

5.62e-0416652C0751372
DiseaseNeuralgia, Ilioinguinal

CXCR4 HMGB1

5.62e-0416652C0751371
DiseaseNeuralgia, Vidian

CXCR4 HMGB1

5.62e-0416652C0042656
Diseasemyopia (is_implicated_in)

MMP2 PRIMPOL

5.62e-0416652DOID:11830 (is_implicated_in)
Diseaseesophagus squamous cell carcinoma (is_marker_for)

JAK2 CXCR4 MMP2

5.91e-0474653DOID:3748 (is_marker_for)
DiseaseRheumatoid Arthritis

SLC25A12 CXCR4 GART MMP2

5.98e-04174654C0003873
DiseaseColorectal Carcinoma

AKAP6 MAP2 ABCA13 VPS13A CNKSR2 UGT3A2 MMP2

8.81e-04702657C0009402
DiseaseOsteogenesis imperfecta

BMP1 CRTAP

9.77e-0421652cv:C0029434
Diseaseperiodontitis (biomarker_via_orthology)

HMGB1 MMP2

9.77e-0421652DOID:824 (biomarker_via_orthology)
Diseasecarotid artery disease (is_implicated_in)

AGTR1 MMP2

1.07e-0322652DOID:3407 (is_implicated_in)
DiseaseDown syndrome (is_marker_for)

ACTR1A GART

1.07e-0322652DOID:14250 (is_marker_for)
Diseasesciatic neuropathy (biomarker_via_orthology)

MAP2 QARS1 OPRL1

1.38e-0399653DOID:11446 (biomarker_via_orthology)
Diseasecolon adenocarcinoma (is_marker_for)

JAK2 MMP2

1.39e-0325652DOID:234 (is_marker_for)
Diseaseunipolar depression, depressive symptom measurement

CNKSR2 PREX1

1.50e-0326652EFO_0003761, EFO_0007006
DiseaseEarly Pregnancy Loss

JAK2 MAP2 AGTR1

1.81e-03109653C3830362
DiseaseMiscarriage

JAK2 MAP2 AGTR1

1.81e-03109653C4552766
DiseaseSpontaneous abortion

JAK2 MAP2 AGTR1

1.81e-03109653C0000786
DiseaseAbortion, Tubal

JAK2 MAP2 AGTR1

1.81e-03109653C0000822
Diseasemean reticulocyte volume

JAK2 VPS13A HMGB1 ITGA4 PREX1 HMGB1P1 OPRL1

1.85e-03799657EFO_0010701
Diseasepneumonia, COVID-19

TBC1D8 MAP2 ST18

2.01e-03113653EFO_0003106, MONDO_0100096
Diseasereticulocyte measurement

TBC1D8 BMP2K VPS13A SLC44A2 PLPPR3 ITGA4 PREX1 HMGB1P1

2.13e-031053658EFO_0010700

Protein segments in the cluster

PeptideGeneStartEntry
RAFFPCFDTPAVKYK

RNPEP

176

Q9H4A4
CLNPILYAFLGAKFK

CXCR4

296

P61073
CLNPLFYGFLGKKFK

AGTR1

296

P30556
IKAGFAGDQIPKYCF

ACTR1B

21

P42025
KPFFCLEKYLGGLFV

ABCA13

2881

Q86UQ4
AFPDTKKTYCFDAFP

ABHD17A

221

Q96GS6
LNYKDPCKAAAFLGD

BMP1

41

P13497
VSYFAFKFAKKDCPV

BMP2K

311

Q9NSY1
GNADGEYCKFPFLFN

MMP2

226

P08253
EYCKFPFLFNGKEYN

MMP2

231

P08253
RCSPKDFNKYFLTFA

JAK2

426

O60674
ASKRDKKFFACAPNY

NUDCD1

491

Q96RS6
FFCKLHFIKGNDPYC

MIR7-3HG

101

Q8N6C7
AFFLFCSEYRPKIKG

HMGB1

101

P09429
FFAQIKGYKRCILFP

HIF1AN

206

Q9NWT6
HPELKVGDYFFGKCF

ERAP1

391

Q9NZ08
TFLLYKFLKECAGEP

PLXNA1

1446

Q9UIW2
KFLKECAGEPLFLLY

PLXNA3

1426

P51805
LYKFLKECAGEPLFS

PLXNA4

1446

Q9HCM2
KYIFPLDDKAAVCGF

PARP4

656

Q9UKK3
CVLKGGYKFFADLLD

HPRT1

66

P00492
DLGGVKKEFFYCLFA

HERC5

721

Q9UII4
KFEKKRYFFFGVLCG

HERC5

761

Q9UII4
RKLYEKFLEFGPENC

CRNKL1

626

Q9BZJ0
KYFNCNKEELPLFSD

CEP126

506

Q9P2H0
LALPDFFKAFYECLA

CRTAP

231

O75718
KPEEFKKLLYGLCFF

DNAH7

3571

Q8WXX0
IKAGFAGDQIPKYCF

ACTR1A

21

P61163
APCYQDYVKKFGENF

ITGA4

181

P13612
DFEYYKQFCVPGFKN

SLC44A2

131

Q8IWA5
KFFLPKACLNFEFFS

IDE

566

P14735
LYCFQFLPFGKGLIK

CPT1B

546

Q92523
NAVCKLYFDLEFNKP

PRIMPOL

106

Q96LW4
KHFYFNATKGFPCLK

HS3ST6

276

Q96QI5
PILYAFLDENFKACF

OPRL1

316

P41146
DTDKLFGYCPLKFEG

MRC1

201

P22897
KPFDKFQFERLGYFS

QARS1

736

P47897
DLAQGFNKKYGEFFP

WARS2

191

Q9UGM6
KKYYLFGRNPDLCDF

PPP1R8

46

Q12972
EKEGPSKYFFFRICH

SLC9C1

591

Q4G0N8
KAGTYLCLLEKFFPD

TRGC1

26

P0CF51
KAGTYLCLLEKFFPD

TRGC2

26

P03986
NYRKAFADCDGFKIP

RASGRP3

286

Q8IV61
AFFLFCSEYHPKIKG

HMGB1P1

101

B2RPK0
LGNVFLKFKDKFCVY

PREX1

131

Q8TCU6
ICADGSYYKFLFNPK

WDR45B

311

Q5MNZ6
PLFDYFLKCKENGAF

IARS1

291

P41252
FTFNDLCIKLGFPYL

SNAPC3

296

Q92966
KFGKVPFDYASFDAQ

ST18

496

O60284
AFPDTKKTYCFDAFP

ABHD17B

201

Q5VST6
DPLLRGFYFDKKSCK

AKAP6

1496

Q13023
CYDKKLEASRPDFFN

CIAO3

246

Q9H6Q4
YKGAKACFLRDIPFS

SLC25A12

481

O75746
DCFKKVLRYEGFFGL

SLC25A13

376

Q9UJS0
EFKGHCYRFFPLNKT

CLEC19A

46

Q6UXS0
AFKACHPKIKSFYFA

CNKSR2

636

Q8WXI2
FPCDKYVKVFHKFLN

ZNF431

176

Q8TF32
ANAFLKEFCLKCPEY

VPS13A

926

Q96RL7
LTDLFKPAKVGFQCY

PLPPR3

41

Q6T4P5
DCFFYDGIKAIFQLG

TBC1D8

686

O95759
FFLFCSEYRPKIKGE

SP100

776

P23497
RAGCKFKFIFQGNPY

TSPYL4

291

Q9UJ04
DFCYLLDKSKQLFNG

SCAI

61

Q8N9R8
PLFFLDYFSCGKLDL

GART

531

P22102
CESPFLAKDFYKNGT

MAP2

786

P11137
TFDYCPFLIAEKLGK

UGT3A2

146

Q3SY77
FKPGFEKYNNLDLFR

ZFC3H1

1701

O60293
CFAPSEKFVKYLRNF

MYO7A

1201

Q13402