Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessresponse to vitamin K

F5 F7

1.41e-055252GO:0032571
HumanPhenoPost-partum hemorrhage

F5 F7

1.05e-041462HP:0011891
HumanPhenoJoint hemorrhage

F5 F7

1.56e-041762HP:0005261
HumanPhenoProlonged bleeding after surgery

F5 F7

1.56e-041762HP:0004846
HumanPhenoProlonged bleeding after dental extraction

F5 F7

2.89e-042362HP:0006298
HumanPhenoPersistent bleeding after trauma

F5 F7

4.31e-042862HP:0001934
PathwayBIOCARTA_EXTRINSIC_PATHWAY

F5 F7

6.09e-0513132M4470
PathwayBIOCARTA_EXTRINSIC_PATHWAY

F5 F7

6.09e-0513132MM1395
PathwayWP_BLOOD_CLOTTING_CASCADE

F5 F7

1.79e-0422132M39480
PathwayWP_BLOOD_CLOTTING_CASCADE

F5 F7

1.96e-0423132MM15936
PathwayREACTOME_FORMATION_OF_FIBRIN_CLOT_CLOTTING_CASCADE

F5 F7

5.71e-0439132M2844
PathwayREACTOME_FORMATION_OF_FIBRIN_CLOT_CLOTTING_CASCADE

F5 F7

5.71e-0439132MM14559
PathwayWP_COMPLEMENT_AND_COAGULATION_CASCADES

F5 F7

1.26e-0358132M39649
PathwayWP_DENGUE2_INTERACTIONS_WITH_COMPLEMENT_AND_COAGULATION_CASCADES

F5 F7

1.30e-0359132M48343
PathwayKEGG_COMPLEMENT_AND_COAGULATION_CASCADES

F5 F7

1.78e-0369132M16894
Pubmed

No significant association between the promoter region polymorphisms of factor VII gene and risk of venous thrombosis in cancer patients.

F5 F7

4.96e-07225220332763
Pubmed

Joint effect of G1691A factor V point mutation and factor VII Arg/Gln(353) gene polymorphism on the risk of premature coronary artery disease.

F5 F7

4.96e-07225211334615
Pubmed

[Association of coagulation factor V, VII gene polymorphisms with coronary heart disease].

F5 F7

4.96e-07225212579498
Pubmed

Structural and functional studies of γ-carboxyglutamic acid domains of factor VIIa and activated Protein C: role of magnesium at physiological calcium.

F5 F7

4.96e-07225223454357
Pubmed

Genetic variation in coagulation factors II, V, VII and fatal MI.

F5 F7

1.49e-06325211858502
Pubmed

Risk of venous thromboembolism and myocardial infarction associated with factor V Leiden and prothrombin mutations and blood type.

F5 F7

1.49e-06325223382263
Pubmed

Prothrombotic gene polymorphisms and atherothrombotic cerebral infarction.

F5 F7

2.97e-06425212859287
Pubmed

The mechanism of inactivation of human factor V and human factor Va by activated protein C.

F5 F7

2.97e-0642527989361
Pubmed

The association between vascular function-related genes and age at natural menopause.

F5 F7

2.97e-06425218030173
Pubmed

The influence of established genetic variation in the haemostatic system on clinical restenosis after percutaneous coronary interventions.

F5 F7

2.97e-06425218064331
Pubmed

Combined effect of hemostatic gene polymorphisms and the risk of myocardial infarction in patients with advanced coronary atherosclerosis.

F5 F7

2.97e-06425218253477
Pubmed

Genetic polymorphisms of hemostasis genes and primary outcome of very low birth weight infants.

F5 F7

2.97e-06425216882823
Pubmed

Polymorphisms of genes encoding coagulation factors II, V, VII, and XIII in relation to pediatric ischemic stroke: family-based and case-control study.

F5 F7

2.97e-06425222931734
Pubmed

A new regulatory function of activated factor V: inhibition of the activation by tissue factor/factor VII(a) of factor X.

F5 F7

2.97e-06425223294934
Pubmed

Factor VIIa/tissue factor generates a form of factor V with unchanged specific activity, resistance to activation by thrombin, and increased sensitivity to activated protein C.

F5 F7

2.97e-06425210026263
Pubmed

Prothrombotic genetic risk factors in patients with coexisting migraine and ischemic cerebrovascular disease.

F5 F7

2.97e-06425211279932
Pubmed

[Hyperhomocysteinemia--one of the factors underlying thrombotic complications in patients with chronic myeloproliferative diseases].

F5 F7

2.97e-06425218220034
Pubmed

Human neutrophil elastase activates human factor V but inactivates thrombin-activated human factor V.

F5 F7

2.97e-0642529242537
Pubmed

Absence of association between polymorphisms in the hemostatic factor pathway genes and carotid intimal medial thickness: the Framingham Heart Study.

F5 F7

4.95e-06525214963283
Pubmed

Correlation of polymorphisms to coagulation and biochemical risk factors for cardiovascular diseases.

F5 F7

4.95e-06525211397354
Pubmed

[Associations of hemostasis factors genes with early development of ischemic heart disease and manifestation of myocardial infarction in young age].

F5 F7

4.95e-06525216353042
Pubmed

The effect of nine common polymorphisms in coagulation factor genes (F2, F5, F7, F12 and F13 ) on the effectiveness of statins: the GenHAT study.

F5 F7

4.95e-06525219415820
Pubmed

Traces of factor VIIa modulate thromboplastin sensitivity to factors V, VII, X, and prothrombin.

F5 F7

4.95e-06525216839353
Pubmed

Polymorphisms in coagulation factors and the risk of recurrent cardiovascular events in men after a first myocardial infarction.

F5 F7

4.95e-06525218284606
Pubmed

Sequence variations within the genes related to hemostatic imbalance and their impact on coronary artery disease in Turkish population.

F5 F7

4.95e-06525216472842
Pubmed

Common polymorphisms and cardiovascular factors in patients with myocardial infarction of Costa Rica.

F5 F7

7.43e-06625218457169
Pubmed

Polymorphisms in prothrombotic genes and their impact on ischemic stroke in a Sardinian population.

F5 F7

1.04e-05725215968394
Pubmed

No evidence of association between prothrombotic gene polymorphisms and the development of acute myocardial infarction at a young age.

F5 F7

1.78e-05925212615788
Pubmed

Hemostatic gene polymorphisms in young Sardinian with non-fatal acute myocardial infarction.

F5 F7

2.22e-051025220036902
Pubmed

Clinical factors such as B-type natriuretic peptide link to factor VII, endothelial NO synthase and estrogen receptor alpha polymorphism in elderly women.

F5 F7

2.22e-051025219560472
Pubmed

Gene polymorphisms implicated in influencing susceptibility to venous and arterial thromboembolism: frequency distribution in a healthy German population.

F5 F7

3.85e-051325217003923
Pubmed

Causal relationship of susceptibility genes to ischemic stroke: comparison to ischemic heart disease and biochemical determinants.

F5 F7

5.92e-051625220161734
Pubmed

Study of 18 functional hemostatic polymorphisms in mucocutaneous bleeding disorders.

F5 F7

5.92e-051625220532885
Pubmed

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.

CCDC25 VPS18 HUWE1 F5 RRP1

8.44e-0564525525281560
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

UTP18 HUWE1 SIRT7 VCL RRP1

8.94e-0565325522586326
Pubmed

Candidate genes and cerebral palsy: a population-based study.

F5 F7

1.03e-042125218977990
Pubmed

Ubiquitination regulates ER-phagy and remodelling of endoplasmic reticulum.

RTN3 HUWE1

1.14e-042225237225996
Pubmed

Genetic risk factors for cerebrovascular disease in children with sickle cell disease: design of a case-control association study and genomewide screen.

F5 F7

1.14e-042225212871600
Pubmed

Perioperative genomic profiles using structure-specific oligonucleotide probes.

F5 F7

1.24e-042325219474452
Pubmed

Genetic associations for activated partial thromboplastin time and prothrombin time, their gene expression profiles, and risk of coronary artery disease.

F5 F7

2.58e-043325222703881
Pubmed

The genomic basis of cerebral palsy: a HuGE systematic literature review.

F5 F7

2.74e-043425219238444
Pubmed

Early embryonic expression of murine coagulation system components.

F5 F7

2.74e-043425211154109
Pubmed

New application of intelligent agents in sporadic amyotrophic lateral sclerosis identifies unexpected specific genetic background.

F5 F7

2.91e-043525218513389
Pubmed

Gender differences in genetic risk profiles for cardiovascular disease.

F5 F7

5.04e-044625218974842
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

RTN3 CCDC25 TUT4 UTP18 HUWE1 RRP1

5.49e-04149625632877691
Pubmed

Proteomic analysis of cerebrospinal fluid extracellular vesicles: a comprehensive dataset.

F5 VCL

5.95e-045025224769233
Pubmed

A candidate gene association study of 77 polymorphisms in migraine.

F5 F7

6.43e-045225219559392
Cytoband22q12.1

CCDC117 SRRD

1.40e-043225222q12.1
ToppCellBrain_organoid-organoid_Tanaka_cellReport-5w-Mesenchymal-Mesoderm|5w / Sample Type, Dataset, Time_group, and Cell type.

THEMIS2 IKZF2 SIRT7 ANKZF1

4.46e-062002540927061536a664b4f7feb9e5b0a8c11ca0d5955c
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-Treg-Treg_2|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

UTP18 AFAP1L2 F5

5.17e-05130253fc68a648161dd314d9ee6612fd039cb12171b8c6
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-Treg-Treg_2|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

UTP18 AFAP1L2 F5

5.17e-051302530f9d3e6297f48ae14d24ac997d8d3a94f337d4d4
ToppCellT_cells-Treg_cells|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

REC8 IKZF2 F5

8.39e-05153253ac793f3176ac3c42c23e7dffc12dd1b057bae4ae
ToppCell356C-Lymphocytic-ILC-ILC-2|356C / Donor, Lineage, Cell class and subclass (all cells)

GCNA REC8 IKZF2

8.72e-051552530fd66c623cb433ceaa893bc21ba2e3b394faaf70
ToppCellVE-CD8-CD4_Treg|VE / Condition, Cell_class and T cell subcluster

REC8 SIRT7 F5

9.76e-05161253a114f4f75859d9ef900e5146686438d051241429
ToppCellCOVID-19-kidney-Podocyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

CRACD AFAP1L2 F5

1.25e-04175253a73e3a65fd5c1e09cb0c2dae20c1a7bfcae49223
ToppCelldroplet-Marrow-BM-1m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANKZF1 F5 VCL

1.25e-04175253c1c722db42da9b8a2a46e516ddb83d9be5e2e504
ToppCell368C-Lymphocytic-CD4_T-cell-Treg_cell_2|368C / Donor, Lineage, Cell class and subclass (all cells)

GCNA CACNA2D4 SIRT7

1.36e-04180253551b8de8d933d11bcd3897aeb2fd033355f958e2
ToppCellMS-CD8-CD4_Treg|MS / Condition, Cell_class and T cell subcluster

REC8 ANKZF1 F5

1.54e-041882532f0e2c7d79ee2d69a5d908c0247dc950c056c30a
ToppCell356C-Lymphocytic-CD4_T-cell-Treg_cell_3|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

LRCH1 F5 AGPAT4

1.57e-0418925399b01893da9f9f7c9528afaffad178285211738b
ToppCellASK428-Epithelial-Transformed_epithelium|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

REC8 AFAP1L2 F5

1.57e-0418925387189275234b5d59484c58acbb14a09903f2b578
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Monocytic-Classical_Monocyte-Mono_c3-CD14-VCAN|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

THEMIS2 RTN3 F5

1.77e-0419725315bcfe6105c0b508811fb9bba0bc4312fea04f4c
ToppCell10x_3'_v3-blood_(10x_3'_v3)|10x_3'_v3 / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

RTN3 F5 VCL

1.77e-041972532d3547107c88c7443fc6425742694e13368a71f5
ToppCellSigmoid-T_cell-Treg|T_cell / Region, Cell class and subclass

REC8 IKZF2 F5

1.80e-04198253e2d2f9f209f77d0c48cfe3e9902c0ae0795511b2
ToppCellParenchyma_COVID-19-Immune-TX-MoAM-4|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

THEMIS2 CACNA2D4 F5

1.80e-04198253a7eed9eeb728a8796e2780090cc244856efd8c65
ToppCellmild-Treg|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

CCDC25 IKZF2 F5

1.80e-041982530269617c0628003d2a13dab98abfd2d15775d16a
ToppCellfacs-Tongue-nan-3m-Epithelial-nan|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HUWE1 LRCH1 VCL

1.82e-041992538d50e1ee58710d896c0204937331d9f4dcd38de0
ToppCellSigmoid-T_cell-cycling_gd_T|Sigmoid / Region, Cell class and subclass

IKZF2 AFAP1L2 AGPAT4

1.85e-042002539769185abae084ffac36420c749625e679b70ca8
ToppCellSigmoid-(1)_T_cell-(18)_cycling_gd_T|Sigmoid / shred on region, Cell_type, and subtype

IKZF2 AFAP1L2 AGPAT4

1.85e-042002536e367abd1a4b87e20eb9095b8337723163e8bbae
ToppCellEntopeduncular-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

THEMIS2 F5

6.99e-0470252be300c0447735aba89df4c3082b81eb5abf22770
ToppCellEntopeduncular-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)--|Entopeduncular / BrainAtlas - Mouse McCarroll V32

THEMIS2 F5

6.99e-04702522121ba6a0beb2a8fdc589ff1063e7d8c2c3c68f6
ToppCellEntopeduncular-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)-|Entopeduncular / BrainAtlas - Mouse McCarroll V32

THEMIS2 F5

6.99e-0470252cd6bca68fe52f451716fc8c0b1745984bc9ec057
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)--|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

F5 F7

8.02e-04752523167beedef7304697e9577270cdeacfc9743cee1
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

F5 F7

8.02e-047525270c346f92a9ac7e33fc1b9dee1dca0bf9ae0a38c
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

F5 F7

8.02e-047525226d6e54ed0a6c3ff57f6269c460177bc7b8bf979
ToppCellHippocampus-Macroglia-OLIGODENDROCYTE-O2-Trf-Oligodendrocyte.Trf.Man1a_(Man1a)|Hippocampus / BrainAtlas - Mouse McCarroll V32

CACNA2D4 F7

9.12e-0480252d42b72ef822f731ff5ff1d04216e91f414c5556e
ToppCellHippocampus-Macroglia-OLIGODENDROCYTE-O2-Trf-Oligodendrocyte.Trf.Man1a_(Man1a)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

CACNA2D4 F7

9.12e-0480252d3ee8fc9b2cb47ee476f4cd8b9fcba14cb9ca759
ToppCellPosterior_cortex-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Vwf_(Vwf)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

F5 F7

1.08e-0387252cc89f4176b70d4eb5b5bf0ff2319b5f1f9e292c0
ToppCellPosterior_cortex-Endothelial-ENDOTHELIAL_STALK-Flt1_2|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

F5 F7

1.08e-038725254cbdf80aae3595eaace20c7cbac763282558213
ToppCellPosterior_cortex-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Vwf_(Vwf)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

F5 F7

1.08e-03872524274e04fa4aca85c2cefd8c5e03d0fa4a4f15536
ToppCellPosterior_cortex-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Vwf_(Vwf)--|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

F5 F7

1.08e-03872528b1a0bd5d6af32afaca19e9c69f86530bbaa309d
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-Treg-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

GCNA IKZF2

2.24e-03126252feedea978d76de326c14da5149e57d0d767271b9
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-Treg-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

GCNA IKZF2

2.24e-031262526311cc64320db7e24a09065ebdf054f5f551b182
ToppCellPBMC-Mild-cDC_2|Mild / Compartment, Disease Groups and Clusters

CRACD IKZF2

2.56e-03135252cb9d834f8301cf53f20e09c3f4cb6a148690196a
ToppCellLPS-antiTNF-Myeloid-Monocytes,_Macrophages-T-cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

THEMIS2 SRRD

2.60e-03136252186be8e1595608004b8216892cb9c7a7f31fbb4d
ToppCell10x5'-blood-Lymphocytic_T_CD4/8-lo-Tgd_CRTAM|blood / Manually curated celltypes from each tissue

IKZF2 NACAD

2.60e-03136252f024015bf60e64b8657e410e24995a1edec85196
ToppCellT_cells-Treg_cells|T_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

IKZF2 F5

2.68e-0313825235880e23ef317862891b54ac6a2265ca03b1d12a
ToppCellLPS_only-Myeloid-Monocytes,_Macrophages-Erythroid|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

THEMIS2 AGPAT4

2.71e-03139252d96e5c17582f1576fa09d6bad35c418b6248448c
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW16-Mesenchymal-Mesoderm|GW16 / Sample Type, Dataset, Time_group, and Cell type.

THEMIS2 SIRT7

2.71e-03139252d441c29852c28928ecb696b4b95e31b30c17116b
ToppCellfacs-Trachea-18m-Hematologic-myeloid-tracheal_macrophage-macrophage_of_trachea|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CRACD F7

2.71e-0313925296e6fed23e7a69f678f85e8e2fe77a7491586b4b
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-Treg-Treg_1|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IKZF2 F5

2.75e-031402529f105687f5749399fd76043fd85da58be30f2caf
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-Treg-Treg_1|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

IKZF2 F5

2.75e-03140252a3be1fb7d2eb44bc123456d03250502938d46d9d
ToppCellP03-Hematopoietic|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

THEMIS2 F5

2.79e-031412524a856521520ea73291f4730fe94c5de88c2b6f0c
ToppCellBLOOD--(3)_MNP-(3)_Classical_Mono-1|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

RTN3 F5

2.83e-03142252395f80e99be4a0ef07fb9d65c74399e7e67c9a8d
ToppCellmetastatic_Brain-Myeloid_cells-CD1c+_DCs|Myeloid_cells / Location, Cell class and cell subclass

REC8 CRACD

2.83e-031422521eecbec805a873fa3539df0574670cf73c18c7b1
ToppCellLPS-IL1RA-Myeloid-Monocytes,_Macrophages-Erythroid|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

THEMIS2 F5

2.91e-031442527c471e332f87d60f4dbed01f3e66bf39995218d0
ToppCellTCGA-Blood_and_Bone_Marrow-Primary_Blood_Derived_Cancer_-_Peripheral_Blood-Leukemia-Acute_Myeloid_Leukemia-7|TCGA-Blood_and_Bone_Marrow / Sample_Type by Project: Shred V9

CRACD IKZF2

2.95e-0314525288090a226ddfa6df59976f025bf0fd84ca0f72ef
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-Treg-Treg_2|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CCDC25 IKZF2

2.95e-03145252734d85ca7a2e5e040f433cadc5f9be1f25cf2e91
ToppCell367C-Lymphocytic-CD4_T-cell-Treg_cell_4|367C / Donor, Lineage, Cell class and subclass (all cells)

IKZF2 F5

2.95e-0314525229422c908d58081e6a748e362a7ac41bf001444c
ToppCell390C-Lymphocytic-NK_cells-NK_cell_D2|390C / Donor, Lineage, Cell class and subclass (all cells)

REC8 CRACD

2.95e-031452523a34c25ff77cd33fdca84742097cc7484066ebc4
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-Treg-Treg_2|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CCDC25 IKZF2

2.95e-031452528ba09eb0fd27f25aa90a3ad75d67a9f79f3f4f43
ToppCell367C-Lymphocytic-CD4_T-cell-Treg_cell_1|367C / Donor, Lineage, Cell class and subclass (all cells)

IKZF2 F5

3.03e-0314725247544227faf9b0f107bcf6be92b5f423b50c8e92
ToppCell368C-Lymphocytic-CD4_T-cell-Treg_cell_1|368C / Donor, Lineage, Cell class and subclass (all cells)

CACNA2D4 IKZF2

3.07e-0314825280470353e12599440f711b6e107730763376d04d
ToppCellP03-Hematopoietic-Immune-immune_cell_unspecified|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

THEMIS2 F5

3.11e-0314925243d756f81d532b5c7f2306e6af9d072d496cbc8e
ToppCellP03-Hematopoietic-Immune|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

THEMIS2 F5

3.11e-031492521c5a2572741c47246d455c865e8e1677c9f49598
ToppCelldroplet-Lung-18m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l21|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IKZF2 ANKZF1

3.11e-0314925265778f19599b4955c0a16f0121237656449431fb
ToppCellRV-16._Neuronal|World / Chamber and Cluster_Paper

CACNA2D4 AFAP1L2

3.11e-031492523a2f8c4173dcf9e3f8d3b8ffddbc597098adf7a9
ToppCelldroplet-Kidney-nan-24m-Lymphocytic-CD45____macrophage|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

F5 AGPAT4

3.15e-0315025234774b015adecc2be56a471fda8994e89a6ad93e
ToppCellPND07-28-samps-Mesenchymal-Pericyte|PND07-28-samps / Age Group, Lineage, Cell class and subclass

AFAP1L2 NACAD

3.15e-031502525b111ec11a642d63fafa7e1422e36f81a2776531
ToppCellPND07-28-samps-Mesenchymal-Pericyte-pericyte_F|PND07-28-samps / Age Group, Lineage, Cell class and subclass

AFAP1L2 NACAD

3.15e-031502522d0d6dc07dcfe28e3d7694c52d15d17dae2fd47b
ToppCell390C-Lymphocytic-NK_cells-NK_cell_D2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

REC8 CRACD

3.23e-03152252595afcfa8b161e291fcaf2afc7336bac9b6fae0f
ToppCell367C-Lymphocytic-CD4_T-cell-Treg_cell_4|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

IKZF2 F5

3.23e-03152252eb7ff36792c3c54ac88cfe976f84016b70b1a1d7
ToppCell367C-Lymphocytic-CD4_T-cell-Treg_cell_4|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

IKZF2 F5

3.23e-031522526d02b50e9e9ecf820f84a79e46d153a4840a1cfe
ToppCellPND10-Immune-Immune_Myeloid-DC-cDC2|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

THEMIS2 F7

3.23e-0315225227718e92715ddc80f28b457a5d6d6a3ac2b205d2
ToppCellMyeloid-C_(Monocyte)|World / shred on cell class and cell subclass (v4)

THEMIS2 F5

3.23e-031522529145dc014ed7f154c158d454dc2b9754396afcca
ToppCellLeuk-UTI-Lymphocyte-T_NK-Treg|Leuk-UTI / Disease, Lineage and Cell Type

IKZF2 F5

3.27e-03153252b24c693b142206d13b29c96faa7f79a1a22bc2ef
ToppCell356C-Lymphocytic-CD4_T-cell-Treg_cell_4|356C / Donor, Lineage, Cell class and subclass (all cells)

IKZF2 F5

3.27e-03153252cda759ab83a271974651fe4faa21ed4f7ecbb3ae
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-Treg-Treg_3|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IKZF2 F5

3.27e-031532527480522a47e367f8facc4f5d599fbaf0b5ad4007
ToppCellIIH-Treg|IIH / Condition, Cell_class and T cell subcluster

IKZF2 F5

3.27e-0315325217704e18833812fcf2a2727b1e3f8a9984ba5b59
ToppCell367C-Lymphocytic-CD4_T-cell-Treg_cell_2|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

IKZF2 F5

3.32e-031542529200e2f1783e54cbc5dfc3b485b57c761af74a46
ToppCell367C-Lymphocytic-CD4_T-cell-Treg_cell_2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

IKZF2 F5

3.32e-03154252b16f3139ce50e70a6a2377b1da7d7877b4000ea1
ToppCell356C-Lymphocytic-CD4_T-cell-Treg_cell_4|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

IKZF2 F5

3.32e-031542521f8d127b657976656e4ec292f26d619943533b86
ToppCellIIH-Treg-CD4_Treg|IIH / Condition, Cell_class and T cell subcluster

IKZF2 F5

3.32e-03154252d2211a892654b92decb208969040920f7ae8ba1e
ToppCell(2)_NK/T-(23)_CD4+_T_cell-(230)_CD4+/CD25+_Reg_T_cell|(23)_CD4+_T_cell / immune cells in Peripheral Blood (logTPM normalization)

IKZF2 F5

3.32e-03154252059bdf6843f94f5028d4df6aa025865a9edb4521
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CRACD F5

3.36e-03155252e7f49e2fdaf184fa6b4e685518004e7deff1316d
ToppCell390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_5|390C / Donor, Lineage, Cell class and subclass (all cells)

GCNA SRRD

3.36e-03155252afdd0aba0f3788c2fb916ffb453c5dd7cde2304c
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CRACD F5

3.36e-031552525a872ca70ae8c30b57f45a6772d7bf565e0c2663
ToppCell390C-Lymphocytic-NK_cells-NK_cell_D2|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

REC8 CRACD

3.36e-03155252216a240bfb82cdefc59e2f342689dbaaacb7c184
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CRACD F5

3.36e-0315525290e629681a72baacc7981b82883866a487638dbc
ToppCell3'_v3-GI_small-bowel-Lymphocytic_T_CD4-Tregs|GI_small-bowel / Manually curated celltypes from each tissue

IKZF2 F5

3.36e-03155252d4ef25965a15eab7679478b9b661e1b4a92f1c59
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-Treg-Treg_3|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

IKZF2 F5

3.40e-0315625253ded973358e3e48054130131e959f0d1f4ef60f
ToppCell343B-Myeloid-Dendritic-pDC|343B / Donor, Lineage, Cell class and subclass (all cells)

GCNA REC8

3.40e-03156252547e2debfc09c07c049a880dded5fda7dd53e156
ToppCellLPS-IL1RA-Hematopoietic_Meg-Ery-Mes-Epi-like|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GCNA CRACD

3.44e-03157252bd45590da540a557dc8096980a45220fccb99505
ToppCellfacs-Marrow-B-cells-18m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

F5 VCL

3.44e-031572520673c7161c25feceee8f1e5fd237171576c42c6b
ToppCellfacs-Marrow-B-cells-18m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

F5 VCL

3.44e-03157252d307d0b48af35e0e1af41ecd3ebf91be8fd29dc0
ToppCell3'_v3-Lung-Lymphocytic_T_CD4/8-lo-Tgd_CRTAM|Lung / Manually curated celltypes from each tissue

IKZF2 AFAP1L2

3.44e-03157252af6eb2214340847bbab7cb209ea27cdc83b62a27
ToppCellLPS-IL1RA-Hematopoietic_Meg-Ery-Mes-Epi-like-Erythroid|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GCNA CRACD

3.44e-0315725200c9a58b033b8b95b0d838f233dd077b62d8b02a
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-Tregs|GI_small-bowel / Manually curated celltypes from each tissue

IKZF2 F5

3.44e-03157252c44bd530e396b08f16f284e185dcb830843959ea
ToppCell367C-Lymphocytic-NK_cells-NK_cell_B|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

THEMIS2 VCL

3.49e-031582521bf692f1e85f677cd62805437b7a59cfaf3b0449
ToppCellAdult-Mesenchymal-myofibroblast_cell-D122|Adult / Lineage, Cell type, age group and donor

CRACD AFAP1L2

3.49e-03158252410fa08c9d880d27e80ec939fa5ba5a41dcb31ab
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Adenocarcinoma_Mixed_Subtype-2|TCGA-Lung / Sample_Type by Project: Shred V9

RTN3 CRACD

3.49e-031582529dea15b28f64206bac0e785df6f36a2cc9010ac7
ToppCellPND10-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

F5 F7

3.49e-03158252bdfa3aa1ffc025d846f14ccb3ca84d889916021f
ToppCell10x5'-Lung-Lymphocytic_T_CD4-Tregs|Lung / Manually curated celltypes from each tissue

IKZF2 F5

3.49e-03158252f433bc189f000efa34e8e09ab32b3fa22bcf64c4
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-Treg-Treg_0|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

IKZF2 F5

3.53e-03159252916d070d099726f22deb71966efccff00f8ea071
ToppCellASK440-Immune-B_cell|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

TUT4 AFAP1L2

3.53e-03159252d31eb59c1b5948df721b829b9a7e806f27cbd41c
ToppCell367C-Lymphocytic-CD4_T-cell-Treg_cell_1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

IKZF2 F5

3.53e-03159252b05fda31b77536a1878f55d3199563b53f9420b2
ToppCell367C-Lymphocytic-CD4_T-cell-Treg_cell_1|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

IKZF2 F5

3.53e-03159252ae53ab7a1339007d0b245c6c291ac61e5ff5b682
ToppCellHealthy/Control-Treg|Healthy/Control / Disease group and Cell class

IKZF2 F5

3.53e-0315925216a322760c99f3e2c3b73cbb399f77868951d3cb
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-Treg-Treg_0|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IKZF2 F5

3.53e-031592526599707107083af6da092fe8984afc8fd89d2bb8
DrugPAAHA

F5 F7

3.47e-063252CID000160605
DiseaseThromboembolism

F5 F7

4.16e-0512242C0040038
Diseaseprothrombin time measurement

F5 F7

1.32e-0421242EFO_0008390
DiseaseVenous Thrombosis

F5 F7

1.32e-0421242C0042487
DiseaseDeep Vein Thrombosis

F5 F7

1.32e-0421242C0149871
Diseasecerebral infarction (is_implicated_in)

F5 F7

2.54e-0429242DOID:3526 (is_implicated_in)
DiseaseAcute Cerebrovascular Accidents

LRCH1 F5

8.84e-0454242C0751956
DiseaseCerebrovascular accident

LRCH1 F5

1.16e-0362242C0038454
Diseasestem Cell Growth Factor beta measurement

F5 AGPAT4

1.70e-0375242EFO_0008292
DiseaseMyocardial Infarction

F5 F7

2.70e-0395242C0027051
Diseasemyocardial infarction (is_implicated_in)

F5 F7

2.93e-0399242DOID:5844 (is_implicated_in)
Diseaseplatelet component distribution width

THEMIS2 VPS18 AFAP1L2 LRCH1

3.01e-03755244EFO_0007984

Protein segments in the cluster

PeptideGeneStartEntry
HKREEEEDDDCPVRK

CCDC117

71

Q8IWD4
EEDDDCPVRKKRITE

CCDC117

76

Q8IWD4
LKEIDEECRGEESRR

AFAP1L2

716

Q8N4X5
LPEEAAAEEERRKIE

REC8

381

O95072
ARAEDCEELLRIEED

LRCH1

416

Q9Y2L9
SDEECDRKPLSREDE

IKZF2

56

Q9UKS7
PEEVACRKEEEERKA

HUWE1

1396

Q7Z6Z7
FPDLAAEKECRDREE

CCDC25

141

Q86WR0
PTEEEIRKICRDEKE

ANKZF1

376

Q9H8Y5
RKDPDLECDEELVRE

CACNA2D4

711

Q7Z3S7
EGRCAEELKRQEEEE

CRACD

351

Q6ZU35
KELPRLQEPEEDEDC

GCNA

6

Q96QF7
EREIKEIPSCEREEK

RTN3

536

O95197
EEDKPAVERCLEELV

UTP18

81

Q9Y5J1
RLKFRDVKCIPDDDE

F5

676

P12259
EELRPGSLERECKEE

F7

66

P08709
EDEIPEKACRRLLEG

RRP1

341

P56182
LKRRQEEVCDDPEEL

SIRT7

71

Q9NRC8
EEVCDDPEELRGKVR

SIRT7

76

Q9NRC8
KRKRECLDESDDEPE

SPDYE3

51

A6NKU9
RKRECLDESDDEPEK

SPDYE3

271

A6NKU9
RECLDESDDEPEKEL

SPDYE3

346

A6NKU9
CADLPEEDEELRKKL

VPS18

741

Q9P253
EEEECKEEAESPERV

THEMIS2

406

Q5TEJ8
RKIAELCDDPKERDD

VCL

416

P18206
DCEDLEIIRNKREDP

SRRD

321

Q9UH36
RRIPLEDIPEDDDEC

AGPAT4

256

Q9NRZ5
EEEKDSRDVLDPRDL

TUT4

1331

Q5TAX3
PRVRLECKEEEEEEE

NACAD

1501

O15069