Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionglutamate-gated receptor activity

GRIK3 GRIN2C

1.71e-0417232GO:0004970
GeneOntologyMolecularFunctionglutamate receptor activity

GRIK3 GRIN2C

4.38e-0427232GO:0008066
GeneOntologyMolecularFunctioncarboxylic acid transmembrane transporter activity

ABCB11 GRIK3 GRIN2C

1.67e-03207233GO:0046943
GeneOntologyMolecularFunctionorganic acid transmembrane transporter activity

ABCB11 GRIK3 GRIN2C

1.69e-03208233GO:0005342
GeneOntologyMolecularFunctiontransmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

GRIK3 GRIN2C

1.95e-0357232GO:1904315
GeneOntologyMolecularFunctionneurotransmitter receptor activity involved in regulation of postsynaptic membrane potential

GRIK3 GRIN2C

2.16e-0360232GO:0099529
GeneOntologyMolecularFunctiontransmitter-gated channel activity

GRIK3 GRIN2C

2.53e-0365232GO:0022835
GeneOntologyMolecularFunctiontransmitter-gated monoatomic ion channel activity

GRIK3 GRIN2C

2.53e-0365232GO:0022824
GeneOntologyMolecularFunctionpostsynaptic neurotransmitter receptor activity

GRIK3 GRIN2C

3.35e-0375232GO:0098960
GeneOntologyMolecularFunctionextracellular ligand-gated monoatomic ion channel activity

GRIK3 GRIN2C

3.52e-0377232GO:0005230
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

ABCB11 GRIK3 GRIN2C

4.46e-03293233GO:0008514
GeneOntologyBiologicalProcessacid secretion

ABCB11 UMOD ABAT

3.41e-0557233GO:0046717
GeneOntologyBiologicalProcessregulation of postsynaptic membrane potential

ABAT GRIK3 MAPK8IP2 GRIN2C

4.36e-05180234GO:0060078
GeneOntologyBiologicalProcessreproductive behavior

ABAT MAPK8IP2 NPAS1

7.46e-0574233GO:0019098
GeneOntologyBiologicalProcessregulation of synaptic transmission, glutamatergic

GRIK3 MAPK8IP2 GRIN2C

1.43e-0492233GO:0051966
MousePhenodecreased circulating triglyceride level

LYN ABCB11 UMOD SAR1B GRHL3

3.46e-05275205MP:0002644
MousePhenodecreased triglyceride level

LYN ABCB11 UMOD SAR1B GRHL3

1.06e-04348205MP:0005318
DomainEGF_3

UMOD CUBN

9.50e-0512232PF12947
DomainEGF_dom

UMOD CUBN

9.50e-0512232IPR024731
DomainIontro_rcpt

GRIK3 GRIN2C

2.19e-0418232IPR001320
DomainLig_chan

GRIK3 GRIN2C

2.19e-0418232PF00060
DomainLig_chan-Glu_bd

GRIK3 GRIN2C

2.19e-0418232PF10613
DomainPBPe

GRIK3 GRIN2C

2.19e-0418232SM00079
DomainIono_rcpt_met

GRIK3 GRIN2C

2.19e-0418232IPR001508
DomainGlu/Gly-bd

GRIK3 GRIN2C

2.19e-0418232IPR019594
DomainLig_chan-Glu_bd

GRIK3 GRIN2C

2.19e-0418232SM00918
DomainANF_receptor

GRIK3 GRIN2C

9.41e-0437232PF01094
DomainANF_lig-bd_rcpt

GRIK3 GRIN2C

9.41e-0437232IPR001828
DomainPeripla_BP_I

GRIK3 GRIN2C

1.05e-0339232IPR028082
DomainEGF_CA

UMOD CUBN

4.98e-0386232PF07645
DomainEGF_Ca-bd_CS

UMOD CUBN

6.29e-0397232IPR018097
DomainEGF_CA

UMOD CUBN

6.54e-0399232PS01187
DomainASX_HYDROXYL

UMOD CUBN

6.67e-03100232PS00010
DomainEGF-type_Asp/Asn_hydroxyl_site

UMOD CUBN

7.47e-03106232IPR000152
DomainEGF_CA

UMOD CUBN

9.79e-03122232SM00179
DomainEGF-like_Ca-bd_dom

UMOD CUBN

1.01e-02124232IPR001881
DomainEGF

UMOD CUBN

1.04e-02126232PF00008
DomainGrowth_fac_rcpt_

UMOD CUBN

1.56e-02156232IPR009030
PathwayREACTOME_METABOLISM_OF_STEROIDS

ABCB11 MVD SAR1B CUBN

3.72e-05154184M27832
PathwayWP_CHOLESTEROL_METABOLISM

ABCB11 MVD SAR1B

9.87e-0572183M46457
Pubmed

Expression of angiopoietin-1, angiopoietin-2, and the Tie-2 receptor tyrosine kinase during mouse kidney maturation.

UMOD ANGPT1

6.26e-06623210446940
Pubmed

PSD-95 promotes Fyn-mediated tyrosine phosphorylation of the N-methyl-D-aspartate receptor subunit NR2A.

LYN GRIN2C

1.50e-0592329892651
Pubmed

Absence of functional peroxisomes does not lead to deficiency of enzymes involved in cholesterol biosynthesis.

MVD GNPAT

2.29e-051123211792727
Pubmed

Conserved and Divergent Features of Human and Mouse Kidney Organogenesis.

UMOD CUBN

5.66e-051723229449453
Pubmed

Ascending Vasa Recta Are Angiopoietin/Tie2-Dependent Lymphatic-Like Vessels.

UMOD ANGPT1

1.05e-042323229237738
Pubmed

Glutamate can act as a signaling molecule in mouse preimplantation embryos†.

GRIK3 GRIN2C

1.14e-042423235746896
Pubmed

Hypoxia-inducible factor prolyl-4-hydroxylation in FOXD1 lineage cells is essential for normal kidney development.

UMOD CUBN

1.56e-042823228847650
Pubmed

Reevaluating human gene annotation: a second-generation analysis of chromosome 22.

SCO2 MAPK8IP2

2.18e-043323212529303
Pubmed

Hnf1b haploinsufficiency differentially affects developmental target genes in a new renal cysts and diabetes mouse model.

UMOD CUBN

2.60e-043623233737325
Pubmed

A genome-scale protein interaction profile of Drosophila p53 uncovers additional nodes of the human p53 network.

JPH1 AGO1

3.21e-044023220308539
Cytoband22q13.33

SCO2 MAPK8IP2

1.67e-043823222q13.33
Cytoband1p34.3

GRIK3 AGO1

4.46e-04622321p34.3
CytobandEnsembl 112 genes in cytogenetic band chr1p34

GRIK3 AGO1

9.46e-03294232chr1p34
CytobandEnsembl 112 genes in cytogenetic band chr22q13

SCO2 MAPK8IP2

1.18e-02330232chr22q13
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Tac2_Myh4|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GRIK3 NPAS1 GRHL3

2.24e-05107233fc07dd90f280191bd643398eac5c8273651d0925
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Tac2_Tacstd2|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ABCB11 GRIK3 NPAS1

3.07e-05119233e868453c02dcf0e07821886b81ca739887d43c67
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Tac2_Tacstd2|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ABCB11 GRIK3 NPAS1

5.31e-0514323324fd24846fbef049af669a57d42fcc18928d2b27
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Crhr2_Efemp1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GRIK3 NPAS1 GRHL3

6.62e-05154233a2adaa4a6cd8708cd579b8efbeb4ff2131c5482e
ToppCellLPS-IL1RA-Stromal_mesenchymal-Fibroblasts-Pericyte_2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MMP19 ABAT GRIN2C

7.15e-051582337f5426585d0d299d2b48e5fcb349950feffdef33
ToppCellHippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Hippocampus / BrainAtlas - Mouse McCarroll V32

ABAT RIMS4 NPAS1

7.56e-05161233b81b346309f3facbfbebd91cae4c5b33c7bd24ef
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Granulocytic|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LYN ABCB11 UMOD

8.72e-051692332e15a9317da4017757d184f7cc91bd66b072ac51
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_B_(ET)-Glut_ET_L5_FEZF2|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ABCB11 ANGPT1 CUBN

8.72e-05169233d0c64ca31053dfc283a07d5ad1117ca7dc1777a7
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_B_(ET)|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ABCB11 ANGPT1 CUBN

8.72e-05169233d79abfbeffd082a4fbffbc1051ffc474374874fa
ToppCellTCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-8|TCGA-Liver / Sample_Type by Project: Shred V9

AKR7A3 ABAT SAR1B

9.03e-05171233c4a919fe3d56ae6df2fcab6686abacc10befc053
ToppCelldroplet-Kidney-nan-21m|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UMOD ABAT CUBN

9.84e-051762330475db3f860de1e216cbdeb886f7a75b9f4fc801
ToppCelldroplet-Kidney|droplet / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UMOD ABAT CUBN

1.05e-041802337e5f497699876ac8e1ce780626c6f5a1f6f5f079
ToppCelldroplet-Kidney-nan-21m-Epithelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UMOD ABAT CUBN

1.09e-04182233942c18a27b22fb33a5200d5717cad972f3ef0576
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

AKR7A3 ABAT CUBN

1.10e-04183233d73cac83cde82665f110baad7cf28db75f9ffe52
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANGPT1 CUBN NPAS1

1.18e-04187233d2ffb2f34f07b0dd5d3cb3ee0275f46ebecf4146
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

AKR7A3 ABAT CUBN

1.29e-0419323355f37fdba469bea9869a34c4d4f00cb1a3b7a73f
ToppCellCOPD-Myeloid|COPD / Disease state, Lineage and Cell class

LYN MMP19 SCO2

1.29e-04193233f58552e286aa27e592497ad78776f58f8ee09841
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

AKR7A3 ABAT CUBN

1.35e-041962334ebcaac758ed01d918de9c1cd383a84457b615f3
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

AKR7A3 ABAT CUBN

1.37e-041972339b038dac4d4d306aa40ec07d79374c4fe9c604a6
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

AKR7A3 ABAT CUBN

1.39e-04198233a9d72b17adfddb6ac1857c5f094280e86582693b
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

AKR7A3 ABAT CUBN

1.39e-04198233b933bd66f544822fcf1f2aa2d928c31500e2b3f4
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

AKR7A3 ABAT CUBN

1.39e-0419823372733b6149b797ac11cc108bc80428b77fbbba78
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

AKR7A3 ABAT CUBN

1.39e-04198233f23559ce6072e3c323f6791ff95269271b0f7ff1
ToppCellPBMC-Mild-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_3|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LYN SCO2 SIRPB1

1.41e-041992339314eb9a89407738626a0384884454b5f9031ee7
ToppCellTracheal-10x3prime_v2-Immune_Myeloid-Macrophage_alveolar-Macro_alv_MT|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

LYN MMP19 SIRPB1

1.41e-041992334e0b73d88b1345ec63a9e5629762341e75beb47f
ToppCellPBMC-Mild-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_3|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

LYN SCO2 SIRPB1

1.41e-04199233dbf0bf09896c46155ae6fbd6307f097799e7e34e
ToppCellCOVID_non-vent-Myeloid|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

LYN SCO2 SIRPB1

1.44e-04200233a40768e8e58c86b8e20bc188b9274ebe412fc765
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-KLHDC8A|Neuronal / cells hierarchy compared to all cells using T-Statistic

GRIK3 ANGPT1 NPAS1

1.44e-0420023305bcde6ce8f1354ef65e4eb9cbd963a92108081c
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-KLHDC8A-|Neuronal / cells hierarchy compared to all cells using T-Statistic

GRIK3 ANGPT1 NPAS1

1.44e-042002331a04331862079092bc04b1010aa9228c0fa3d8c5
ToppCellNeuronal-Inhibitory-iA-iA_1(SST_PAX6)-PAX6|Neuronal / cells hierarchy compared to all cells using T-Statistic

ANGPT1 CUBN NPAS1

1.44e-042002338a8f9d9e5ffab3f736c4bd0a5bb616d442d137d1
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-KLHDC8A--L5-6|Neuronal / cells hierarchy compared to all cells using T-Statistic

GRIK3 ANGPT1 NPAS1

1.44e-04200233fb56d430957e73fba17db7bc0127ecf3577e0867
ToppCellCOVID_non-vent-Myeloid-Monocytic-CD14+_Monocyte|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

LYN SCO2 SIRPB1

1.44e-04200233465ed50e0b92bb8c27ffe56d816f063a45b52be9
ToppCellCOVID_non-vent-Myeloid-Monocytic|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

LYN SCO2 SIRPB1

1.44e-042002334243a9d32f3a11141284d0d944cb81194b532876
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Igfbp4_Mab21l1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ANGPT1 NPAS1

1.11e-039623278f19fee755061b4144b1beebb60f4e8bc4dbf0d
ToppCellFrontal_cortex-Macroglia-ASTROCYTE-Gja1-Gfap-_astrocytes_(Gja1)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ABCB11 GRIN2C

1.13e-0397232031bc124739541b0b2591e1b6ef41f12adfd5c18
ToppCellFrontal_cortex-Macroglia-ASTROCYTE-Gja1-Gfap-_astrocytes_(Gja1)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ABCB11 GRIN2C

1.13e-03972320cd19f619f10a35d3107518aa83c0eda0572930a
ToppCellFrontal_cortex-Macroglia-ASTROCYTE-Gja1-Gfap-_astrocytes_(Gja1)--|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ABCB11 GRIN2C

1.13e-039723233330ac2de9e49d78b478f175068999235c9af25
ToppCellTCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Dedifferentiated_Liposarcoma-3|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

ABCB11 ABAT

1.42e-031092325d194bf95eb777fb4d01bbe5b1639f17ea1bc11a
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Myh8_Fibin|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GRIK3 NPAS1

1.53e-03113232feb3c6a7723263d58e5ce020a0097fedfcf78ca8
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Hpse_Cbln4|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GRIK3 NPAS1

1.58e-03115232ac73aa06e617ed791c6ae9e38189bac74188c27b
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Esm1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NPAS1 GRHL3

1.75e-03121232056d0f0f7a4d1b2d38b83647bbe4468b7c959ce6
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Hpse_Sema3c|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GRIK3 NPAS1

1.78e-03122232eae9d94f8510ac0f434942451d55c7260977b178
ToppCellTCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Monophasic_Synovial_Sarcoma-3|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

GRIK3 NPAS1

1.81e-03123232ad22e41661e7d26d40cd133702003281ccfbedbf
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-Airway|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ABCB11 GRIN2C

1.84e-03124232a7b7d8b14d1218194da8fcf69b4780b6e9469332
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Chrna2_Ptgdr|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GRIK3 NPAS1

1.86e-03125232d05556ea185c15815a4f8643f1c01185badbeece
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Calb2_Necab1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GRIK3 GRHL3

1.89e-0312623228fbe63f7bc628b32d8e86bf9e80657e776dd1cc
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Hpse_Cbln4|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GRIK3 NPAS1

1.89e-0312623294bd9cfe982b41a3114885173eab55feb0fbbbae
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_26.46.91|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MMP19 ANGPT1

1.98e-031292326abdba987c8528f7cb90b32dc01796e02c7352c9
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Tac2_Myh4|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GRIK3 NPAS1

1.98e-03129232f83187c0bb06528127b8d2d56674ab1946846951
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Crh_4930553C11Rik_|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GRIK3 NPAS1

1.98e-031292326bc85761dea1f97c19bb379a99e4daf85d53201e
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Esm1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NPAS1 GRHL3

2.04e-031312323cb4b272e28ee9bad6d874f64a7aae18352a6cfb
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_1|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

ABCB11 MMP19

2.08e-03132232893b7ec2a2d8a140cc98575d1beca1189f053e9a
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Mme_Fam114a1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GRIK3 GRHL3

2.11e-03133232fc319644868078ea0f88a71d55f5e858c6848b50
ToppCellLPS-antiTNF-Epithelial_alveolar-Mes-like|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

JPH1 GRIK3

2.14e-0313423264979e1a056b7406e1be39c5ebe2f8d731ac3c17
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma-3|TCGA-Brain / Sample_Type by Project: Shred V9

AGO1 GRHL3

2.17e-031352323351e8b9e417397c5fa9f856184ff24ce1a27242
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Crhr2_Efemp1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GRIK3 NPAS1

2.20e-03136232e3a2425ba5ef538dbacab1479e682837ae42a888
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Gpc3_Slc18a3|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ANGPT1 NPAS1

2.23e-03137232d346086f42d8f04d3fa67fe696834284acdc7080
ToppCell10x3'2.3-week_12-13-Hematopoietic-HSC/MPP_and_pro-MPP_myeloid|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

ANGPT1 CUBN

2.33e-03140232eb1d22f5f5dbf60b6485464baec4be9b3060f65c
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Crh_4930553C11Rik_|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GRIK3 NPAS1

2.36e-03141232ad9a25569c142fb68ded34aeba0cd9be8124ce56
ToppCellLPS-antiTNF-Epithelial_alveolar-Mes-like-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

JPH1 GRIK3

2.40e-031422325690eee2ce1ecd02e34eac4193578bd13c4228b9
ToppCellsevere_COVID-19-B_cell|World / disease group, cell group and cell class (v2)

MMP19 CUBN

2.43e-0314323228b0e168126a9fe60541dc12bfab385b7a0a2342
ToppCellTCGA-Head_and_Esophagus-Primary_Tumor-Head_and_Neck_Carcinoma-Squamous_Cell_Carcinoma-5|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9

ABAT GRHL3

2.46e-0314423276c0e551864c4faab7528c4ecf1a40d7ea60569f
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Lmo1_Myl1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ANGPT1 NPAS1

2.46e-031442320322fef818a963be00535d5f141f028d43de5c6a
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Chrna2_Ptgdr|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GRIK3 NPAS1

2.46e-0314423271107275767a0728541a3695715c44874b3e5efc
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Lmo1_Myl1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ANGPT1 NPAS1

2.50e-03145232590ba937c741ae67460f303eca88b1cd3ac87f64
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Chrna2_Glra3|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GRIK3 NPAS1

2.56e-0314723250e86860a94be103092c40e39a172eac92372f0d
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Lmo1_Fam159b|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ANGPT1 NPAS1

2.60e-031482329205b26e0d042b342cc643cda0f4f3f8bb392d00
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Myh8_Etv1_|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GRIK3 GRHL3

2.60e-031482324d43efee96a6493abd78e9ca41aab73db0c80626
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-Goblet_cell,_top_of_crypt_(Distal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCB11 UMOD

2.60e-03148232dfd3f2c4b884ea9e23831a242a89ac985b409640
ToppCellfacs-Skin-nan-18m-Myeloid-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LYN MMP19

2.63e-0314923223a1b95c12f2e3708dc003e13fab423e89821f11
ToppCellfacs-Skin-nan-18m-Myeloid|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LYN MMP19

2.63e-03149232bb18a18b891af85849b9658d774053f839c9a8e1
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Lmo1_Fam159b|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ANGPT1 NPAS1

2.63e-0314923298ae408d2d0347865875ff8bbd89d359decea526
ToppCellfacs-Skin-nan-18m-Myeloid-macrophage|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LYN MMP19

2.63e-03149232c53a3226adc8fd0eaaa842b6a96442287580cbe0
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-3|TCGA-Brain / Sample_Type by Project: Shred V9

AGO1 GRHL3

2.63e-03149232768877bade04ca0321593b8470b5011ad8270431
ToppCelldroplet-Liver-nan-3m-Epithelial-Hepatocyte_(Pericentral,_Midlobular,_Periportal)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCB11 ABAT

2.70e-03151232cc9632b58522e2ba3ad36a0b8d37c7c9c8b636c4
ToppCell390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

LYN SIRPB1

2.77e-03153232e7d20c88466ff81db613869cf7a6a4bb95fd6c2f
ToppCell10x5'v1-week_14-16-Hematopoietic-HSC/MPP_and_pro-MEMP|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

ABCB11 ANGPT1

2.77e-0315323214753baa9980f75206fefc3c8b43685fd4178a43
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Arhgap36_Hmcn1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ANGPT1 NPAS1

2.77e-031532329c6fce56300ba5053efda59a438d63a808c497c0
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_ALM_Cpa6|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

JPH1 GRIK3

2.81e-0315423212cbc38bc1f7231c67e1d2d5e86e95bc12e24682
ToppCellFetal_29-31_weeks-Immune-dendritic_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

LYN GRHL3

2.85e-031552329f937ae48767fdcf1a944af4de0530d9c0ab441d
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Hpse_Sema3c|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GRIK3 NPAS1

2.85e-031552325c7b68b59244525e3714806c205a57a2daebf423
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Degenerative_Medullary_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

GRIK3 MAPK8IP2

2.88e-03156232d34f386985dd17293b1e320d732ab11b46be76ce
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Myh8_Fibin|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GRIK3 NPAS1

2.92e-03157232741d79c10cb87fa7f14080c6fccb1553c3a20bad
ToppCell367C-Lymphocytic-ILC|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

MMP19 NPAS1

2.92e-03157232f511871e1a004c6e9af08ee325ab1bfc41807487
ToppCellPND28-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MMP19 CUBN

2.95e-031582326811dc4f101dfa9a9cc13d949760d43aa522bf3b
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Neural-neural_cell-Schwann_Cell_/_Neural|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GRIK3 GRIN2C

3.03e-0316023214dfa519e68bab4bce890ddb66fa7763f18d9f19
ToppCelldroplet-Trachea-3m-Hematologic-myeloid-granulocyte-granulocyte_l1-4|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LYN MMP19

3.03e-031602326329b0f02f9509086e563c2ed762a8ec693883b5
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Neural|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GRIK3 GRIN2C

3.03e-031602325b7789d4668ed7732babedc32d812233b430e0bd
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Neural-neural_cell-Schwann_Cell_/_Neural-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GRIK3 GRIN2C

3.03e-03160232bba1486faaad5299e10f4fe17c6d149c28dc2560
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Chrna2_Glra3|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GRIK3 NPAS1

3.03e-031602320bfdaf979e6f128cba2928ce16bca4d3deff8ac9
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Neural-neural_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GRIK3 GRIN2C

3.03e-03160232839bbdfd4e4c7b48260c8bfb7670378634405e1d
ToppCellPCW_13-14-Neuronal-Neuronal_postreplicative-neuro_immature_neuronal_(2)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

GRIK3 MAPK8IP2

3.06e-03161232bb9cb42882aaa4a1ecf9b480c0e7ac302f2c0d5d
ToppCell10x5'v1-week_17-19-Hematopoietic-HSC/MPP_and_pro-HSC/MPP|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

JPH1 ANGPT1

3.06e-03161232aee74a2e7a8acd2950341963f1c04b59c7862183
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GRIK3 NPAS1

3.06e-03161232dccb61d5e17a8f1c6d1fc146ee389f567659a0f0
ToppCellTCGA-Mesothelium-Primary_Tumor-Mesothelioma-Epitheliod-1|TCGA-Mesothelium / Sample_Type by Project: Shred V9

SERGEF NPAS1

3.06e-031612329e03aa7c50b4e8cf1f726a524b5b03af886535b1
ToppCellPND28-Immune-Immune_Myeloid-Monocytic-Macrophage-AM|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MMP19 CUBN

3.10e-03162232d712bc31840ad1523e3dbf884acbb428a8995001
ToppCellnormal_Lymph_Node-Myeloid_cells-Monocytes|Myeloid_cells / Location, Cell class and cell subclass

ABAT GRIN2C

3.14e-031632327d7f18e5c99be125e95bc180823430291b770d05
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Gpc3_Slc18a3|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ANGPT1 NPAS1

3.14e-03163232ec9a20cfe0d69430f9c68cddd1ab0e4a3e4554b8
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5|367C / Donor, Lineage, Cell class and subclass (all cells)

MAPK8IP2 GRIN2C

3.18e-031642324a834a7908d8aa643a2096c52430dad795898474
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_VIP_PRSS8|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANGPT1 NPAS1

3.18e-03164232ed7e0c8ccad7d19b9cc72d70391936ff5e698f28
ComputationalGenes in the cancer module 13.

MMP19 ANGPT1

3.40e-0415202MODULE_14
ComputationalGenes in the cancer module 516.

MMP19 ANGPT1

3.89e-0416202MODULE_516
ComputationalGenes in the cancer module 178.

MMP19 ANGPT1

4.40e-0417202MODULE_178
ComputationalGenes in the cancer module 165.

LYN UMOD NPAS1

4.44e-0482203MODULE_165
ComputationalGenes in the cancer module 444.

MMP19 ANGPT1

4.94e-0418202MODULE_444
ComputationalAngiogenesis.

MMP19 ANGPT1

6.76e-0421202MODULE_362
ComputationalNeighborhood of HMGA2

MMP19 SIRPB1 GRIN2C

1.45e-03123203GCM_HMGA2
DrugCX516

LYN GRIK3 GRIN2C

1.37e-0622233CID000148184
Drug6,7-dinitroquinoxaline

GRIK3 GRIN2C GRHL3

4.82e-0633233CID002724608
Drugperzinfotel

GRIK3 GRIN2C

2.72e-058232CID006918236
DrugCelecoxib

ABCB11 ABAT GRIK3 MVD GRIN2C

3.15e-05376235ctd:D000068579
DrugL-Glutamic Acid

ABAT GRIK3 GRIN2C

4.32e-0568233DB00142
DrugS(-)Eticlopride hydrochloride [97612-24-3]; Up 200; 10.6uM; HL60; HT_HG-U133A

MMP19 ABAT MVD GRIN2C

4.49e-052002343056_UP
Drugfelbamate

ABAT GRIK3 GRIN2C

4.72e-0570233CID000003331
DrugT2755

ABAT GRIK3 GRIN2C

4.92e-0571233CID000005514
DrugAC1L1B1W

ABAT GRIK3 GRIN2C

8.13e-0584233CID000001248
Drugremacemide

ABAT GRIN2C

8.82e-0514232CID000060510
Drughexachlorophene

JPH1 GRIK3 GRIN2C

9.99e-0590233CID000003598
DrugACEA-1011

GRIK3 GRIN2C

1.02e-0415232CID000127872
Drugargiopine

GRIK3 GRIN2C

1.16e-0416232CID000122294
Drug3HPG

GRIK3 GRIN2C

1.32e-0417232CID000001217
DrugEN-1530

ABAT GRIK3 MVD GRIN2C

1.60e-04278234CID000004425
DrugIDRA 21

GRIK3 GRIN2C

1.83e-0420232CID000003688
DrugNS 102

GRIK3 GRIN2C

2.23e-0422232CID005282252
Drugkynurenic acid

ABAT GRIK3 GRIN2C

2.46e-04122233CID000003845
Drugmuscimol

ABAT GRIK3 GRIN2C

2.90e-04129233CID000004266
Druganiracetam

GRIK3 GRIN2C NPAS1

2.96e-04130233CID000002196
Drug2-chloropropionate

GRIK3 GRIN2C

3.37e-0427232CID000011734
DrugAC1NUW3V

GRIK3 GRIN2C

3.90e-0429232CID005462126
DrugPb-D

MVD MAPK8IP2 GNPAT

3.92e-04143233CID000070065
DrugLY293558

GRIK3 GRIN2C

4.17e-0430232CID000127894
DrugAC1L32TU

GRIN2C GRHL3

4.17e-0430232CID000107831
Drugcis-2,3-piperidine dicarboxylic acid

GRIK3 GRIN2C

4.17e-0430232CID000001226
Drug4-methylglutamic acid

GRIK3 GRIN2C

4.46e-0431232CID000005365
DrugAstemizole [68844-77-9]; Up 200; 8.8uM; MCF7; HT_HG-U133A

MMP19 MVD SERGEF

4.68e-041522336807_UP
DrugAC1O5D5R

ABCB11 ANGPT1

5.06e-0433232CID006482240
Drugkainite

GRIK3 GRIN2C

5.69e-0435232CID000164810
Drugglutamic acid diethyl ester

ABAT GRIN2C

6.02e-0436232CID000073960
DrugR,S)-AMPA

GRIK3 GRIN2C

6.02e-0436232CID000001221
Drughaloperidol

AKR7A3 ABAT GRIK3 GRIN2C

6.03e-04394234CID000003559
Druggamma-Glu-Gly

GRIK3 GRIN2C

6.36e-0437232CID000100099
Druggabapentin

ABAT MVD GRIN2C

6.38e-04169233CID000003446
DrugGAMs

GRIK3 GRIN2C

6.71e-0438232CID000002935
DrugL-BMAA

GRIK3 GRIN2C

6.71e-0438232CID000028558
DrugCGS 19755

GRIK3 GRIN2C

6.71e-0438232CID000068736
DrugDETC-MeSO

GRIK3 GRIN2C

7.07e-0439232CID003035711
DrugHA-966

GRIK3 GRIN2C

7.07e-0439232CID000001232
Drug7-OH-DPAT

GRIK3 GRIN2C

7.07e-0439232CID000001219
Drugstrychnine HCl

ABAT GRIK3 GRIN2C

7.78e-04181233CID000005304
Drugpicrotoxin

ABAT GRIK3 GRIN2C

7.78e-04181233CID000031304
Drug1-(2-trifluoromethoxyphenyl)-2-nitroethanone

AKR7A3 MMP19 ABAT

8.16e-04184233ctd:C576882
DrugAC1Q6X9N

ABCB11 CUBN

8.20e-0442232CID000072205
DrugLY341495

GRIK3 GRIN2C

8.60e-0443232CID006324636
DrugJoro spider toxin

GRIK3 GRIN2C

8.60e-0443232CID000119582
Drugdiazepam

ABAT GRIK3 GRIN2C

8.82e-04189233CID000003016
Drugsaclofen

ABAT GRIN2C

9.00e-0444232CID000122150
Drug7-chlorokynurenic acid

GRIK3 GRIN2C

9.41e-0445232CID000001884
Drugphilanthotoxin

GRIK3 GRIN2C

9.41e-0445232CID000115201
Drug2-propylpentanoic acid; Down 200; 500uM; MCF7; HT_HG-U133A

LYN MMP19 MVD

9.66e-041952331665_DN
Drugretinoic acid; Down 200; 1uM; HL60; HG-U133A

MMP19 ABAT CUBN

9.80e-04196233390_DN
DrugICI 182,780; Up 200; 1uM; MCF7; HT_HG-U133A

LYN MAPK8IP2 SERGEF

9.94e-041972335202_UP
DrugRanitidine hydrochloride [66357-59-3]; Up 200; 11.4uM; PC3; HT_HG-U133A

ABAT MAPK8IP2 SERGEF

1.01e-031982332088_UP
DrugMoxonidine [75438-57-2]; Up 200; 16.6uM; HL60; HT_HG-U133A

MMP19 MAPK8IP2 ANGPT1

1.02e-031992332923_UP
DrugNaCN

ABAT GRIN2C

1.03e-0347232CID000008929
Drugflurothyl

ABAT GRIN2C

1.03e-0347232CID000009528
Drugsodium 4-phenylbutyrate; Down 200; 100uM; HL60; HG-U133A

SCO2 MVD GRIN2C

1.04e-03200233363_DN
Drugarachidonic acid sodium salt; Up 200; 10uM; MCF7; HG-U133A

MMP19 MAPK8IP2 GRIN2C

1.04e-03200233604_UP
DrugIsotretinoin

LYN NDUFB3 MVD SAR1B GNPAT

1.04e-03799235ctd:D015474
Drugfelbamate

AKR7A3 GRIN2C

1.07e-0348232ctd:C047360
DrugOne-time

GRIK3 GRIN2C

1.07e-0348232CID000040813
Diseasekidney disease (implicated_via_orthology)

LYN UMOD CUBN

4.33e-0641233DOID:557 (implicated_via_orthology)
DiseaseParkinsonism (biomarker_via_orthology)

LYN ABAT

3.21e-0434232DOID:0080855 (biomarker_via_orthology)
DiseaseSchizophrenia

GRIK3 SIRPB1 GRIN2C GNPAT NPAS1

5.10e-04883235C0036341
Diseaseresponse to opioid

ABAT ANGPT1

1.03e-0361232EFO_0008541
Diseaseplatelet component distribution width

LYN SIRPB1 ANGPT1 CUBN

2.56e-03755234EFO_0007984
DiseasePsychotic Disorders

GRIK3 NPAS1

2.80e-03101232C0033975

Protein segments in the cluster

PeptideGeneStartEntry
GRFFGNTWAEMYRNR

AKR7A3

221

O95154
GVWDMRGKQFYNGIE

AGO1

431

Q9UL18
AQRWGIRKGIVMGFF

ABCB11

311

O95342
DFQRGWKEYKMGFGN

ANGPT1

336

Q15389
GRNEAWRYMGGFAKS

NDUFB3

46

O43676
GQVMTGYYRWLQRAG

NPAS1

361

Q99742
FMWYRSKERGQRGFS

ABAT

176

P80404
WFRGFNMRTGERGVF

MAPK8IP2

641

Q13387
YMGEWKNDKRNGFGV

JPH1

281

Q9HDC5
AAMSWQDGRVYFFKG

MMP19

431

Q99542
RSLYGGFVEWQMGEQ

MVD

161

P53602
GRREKGFQMQWFVYG

CUBN

1376

O60494
QVRNMGFGDGFWRQR

GRHL3

591

Q8TE85
AFFMRRTFGGNKLYW

GNPAT

206

O15228
KRLGAGQFGEVWMGY

LYN

251

P07948
WRFGGRFMNFIKEAQ

GRIK3

356

Q13003
KADFRGQWVLMYFGF

SCO2

116

O43819
MFTWGRADYGQLGRK

SERGEF

286

Q9UGK8
WGNYGRMERKQFMGV

RIMS4

201

Q9H426
MWFRGAGAGRELIYN

SIRPB1

66

O00241
GWYRFVGQGGARMAE

UMOD

201

P07911
LKRQGYGEGFRWMAQ

SAR1B

181

Q9Y6B6
RVRGVWNGMIGEVYY

GRIN2C

486

Q14957