Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyCellularComponentnuclear protein-containing complex

THOC2 NVL KDM2B CASP8 SMARCC2 MYH9 RBM41

1.92e-041377207GO:0140513
HumanPhenoMegakaryocyte dysplasia

MYH9 SAMD9

1.15e-05562HP:0031689
MousePhenoabnormal prenatal body size

THOC2 KDM2B CASP8 SMARCC2 RSU1 MYH9 KIF3A DOT1L

3.13e-061116148MP:0010866
MousePhenoabnormal embryo size

KDM2B CASP8 SMARCC2 RSU1 MYH9 KIF3A DOT1L

1.53e-05956147MP:0001697
MousePhenoabnormal prenatal growth/weight/body size

THOC2 KDM2B CASP8 SMARCC2 RSU1 MYH9 KIF3A DOT1L

2.76e-051493148MP:0004196
MousePhenoembryonic lethality during organogenesis, complete penetrance

KDM2B CASP8 MYH9 CTNNAL1 KIF3A DOT1L

3.28e-05700146MP:0011098
MousePhenoabnormal embryonic growth/weight/body size

KDM2B CASP8 SMARCC2 RSU1 MYH9 KIF3A DOT1L

1.10e-041295147MP:0002088
MousePhenoembryonic lethality during organogenesis

KDM2B CASP8 MYH9 CTNNAL1 KIF3A DOT1L

1.16e-04876146MP:0006207
MousePhenodecreased embryo size

KDM2B CASP8 MYH9 KIF3A DOT1L

3.22e-04659145MP:0001698
MousePhenoabnormal actin cytoskeleton morphology

MYH9 CTNNAL1

5.13e-0434142MP:0020849
MousePhenowavy neural tube

CASP8 KIF3A

6.08e-0437142MP:0000930
MousePhenoabnormal nervous system development

THOC2 KDM2B CASP8 SPEF2 CTNNAL1 KIF3A

8.32e-041257146MP:0003861
MousePhenoabnormal motile cilium physiology

SPEF2 KIF3A

1.15e-0351142MP:0013209
MousePhenoabnormal cilium physiology

SPEF2 KIF3A

1.25e-0353142MP:0013208
MousePhenokinked neural tube

KDM2B CASP8

1.44e-0357142MP:0003400
MousePhenoabnormal vitelline vasculature morphology

CASP8 MYH9 DOT1L

1.49e-03235143MP:0003229
DomainP-loop_NTPase

NVL MYH9 SPEF2 KIF3A SAMD9

1.67e-03848205IPR027417
DomainF-box

KDM2B FBXO40

2.31e-0367202PF00646
DomainFBOX

KDM2B FBXO40

2.66e-0372202PS50181
DomainF-box_dom

KDM2B FBXO40

2.88e-0375202IPR001810
PathwayREACTOME_CHROMATIN_MODIFYING_ENZYMES

KDM2B SMARCC2 DOT1L

3.81e-04175123MM14941
PathwayREACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS

CASP8 STK26

4.35e-0437122MM14488
PathwayREACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS

CASP8 STK26

4.59e-0438122M495
Pubmed

SAMD9 Promotes Postoperative Recurrence of Esophageal Squamous Cell Carcinoma by Stimulating MYH9-Mediated GSK3β/β-Catenin Signaling.

MYH9 SAMD9

1.88e-06420236757050
Pubmed

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.

THOC2 KDM2B SMARCC2 MYH9 STK26 KIF3A DOT1L

3.85e-06124720727684187
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

THOC2 SENP6 ENSA SPAG7 MYH9 CKAP2

1.04e-0593420633916271
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

NVL SENP6 KDM2B SMARCC2 DOT1L

2.00e-0560820536089195
Pubmed

Identification of proteins that interact with the central coiled-coil region of the human protein kinase NEK1.

CTNNAL1 KIF3A

2.44e-051320214690447
Pubmed

Identification and functional characterization of transcriptional activators in human cells.

KDM2B SMARCC2 RSU1 DOT1L

7.08e-0539820435016035
Pubmed

Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.

THOC2 NVL SMARCC2 MYH9 DOT1L

9.68e-0584720535850772
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

THOC2 NVL SENP6 CASP8 SMARCC2

1.69e-0495420536373674
Pubmed

Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.

THOC2 NVL SMARCC2 SPAG7

2.17e-0453320430554943
Pubmed

Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.

THOC2 SENP6 SPEF2

2.23e-0420820333230847
Pubmed

An emerin "proteome": purification of distinct emerin-containing complexes from HeLa cells suggests molecular basis for diverse roles including gene regulation, mRNA splicing, signaling, mechanosensing, and nuclear architecture.

SMARCC2 MYH9

3.49e-044820217620012
Pubmed

Identification of Jmjd3 as an Essential Epigenetic Regulator of Hox Gene Temporal Collinear Activation for Body Axial Patterning in Mice.

KDM2B DOT1L

3.64e-044920234368113
Pubmed

Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B.

KIF3A CKAP2 DOT1L

3.87e-0425120329778605
Pubmed

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.

THOC2 SPAG7 KIF3A CKAP2

4.48e-0464520425281560
Pubmed

Proteomic characterization of chromosomal common fragile site (CFS)-associated proteins uncovers ATRX as a regulator of CFS stability.

THOC2 SMARCC2 MYH9 CKAP2

4.67e-0465220431180492
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

THOC2 NVL SMARCC2 MYH9

4.70e-0465320422586326
Pubmed

Unbiased Identification of trans Regulators of ADAR and A-to-I RNA Editing.

THOC2 SMARCC2 MYH9

4.84e-0427120332433965
Pubmed

New nomenclature for chromatin-modifying enzymes.

KDM2B DOT1L

4.92e-045720218022353
Pubmed

Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.

THOC2 NVL MYH9

5.48e-0428320330585729
Pubmed

Systematic analysis and nomenclature of mammalian F-box proteins.

KDM2B FBXO40

5.63e-046120215520277
InteractionH2BC8 interactions

NVL SENP6 KDM2B SMARCC2 SPAG7 MYH9 CKAP2

8.43e-07576207int:H2BC8
InteractionSAMD9 interactions

SMARCC2 MYH9 SAMD9

2.70e-0628203int:SAMD9
InteractionH3-3A interactions

NVL SENP6 KDM2B SMARCC2 MYH9 DOT1L

6.40e-05749206int:H3-3A
InteractionSOX7 interactions

KDM2B SMARCC2 DOT1L

7.04e-0582203int:SOX7
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-Stress_sig-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CASP8 MYH9 STK26 SAMD9

1.57e-06195204662b50a2aa97373bf343b88caace9717049c722a
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-Stress_sig|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CASP8 MYH9 STK26 SAMD9

1.57e-061952049b7157b5e4b81bc35b0e6d9b954279160ea57324
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-CD8_NK_sig-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CASP8 MYH9 STK26

5.66e-05169203f06118754fa62c580b4bcbecff6f9e5fdc2106a0
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-CD8_NK_sig|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CASP8 MYH9 STK26

7.53e-0518620371e87c4c755ab607689cb050f5a363cb520a0f53
ToppCellPBMC-Severe|PBMC / Location, Disease Group, Cell group, Cell class (2021.03.09)

RSU1 MYH9 CTNNAL1

8.92e-05197203af10b5e6e959e2ced01ad066f906941bc4194cc3
ToppCellPBMC-Severe|PBMC / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RSU1 MYH9 CTNNAL1

8.92e-051972033ff23b86d310ace388d2efb3ee73dd47c46f363e
ToppCellCOVID-19_Severe-PLT_0|World / Disease Group and Platelet Clusters

RSU1 ENSA MYH9

9.06e-05198203d508d69d8de233573aee14f17dd8ef054654aa54
ToppCellcritical-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

SPEF2 KIF3A CCDC190

9.06e-05198203ee2c8385c0bf4ea9f5c9517b52cf131af3fbdd40
ToppCellMegakaryocytic-erythropoietic-Megakaryo-cells-Megakaryocyte|Megakaryocytic-erythropoietic / Lineage, cell class and subclass

RSU1 ENSA MYH9

9.06e-051982038cedd6ae249ac1c08441b90901a8bb2360feba17
ToppCell(01)_IL1RL1+-(2)_GFP_FOXI1|(01)_IL1RL1+ / shred by cell type by condition

THOC2 CTNNAL1 SAMD9

9.19e-05199203a2f7d0cabf35b80fe239fae34a77bf9344d5d743
ToppCellSigmoid-T_cell-cycling_gd_T|T_cell / Region, Cell class and subclass

CTNNAL1 CKAP2 DOT1L

9.33e-052002034e489ecf472857357d45e9f6c7a812aa48b72ebf
ToppCellLPS-IL1RA-Lymphocytic_NKT-T_cells-Erythroid|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CASP8 STK26

1.48e-03128202c2045f052cc713e52312eb015825711576fcb6c5
ToppCellControl-PLT_3|Control / Disease Group and Platelet Clusters

ENSA MYH9

1.76e-0314020282ea671f61d55f6896d903c5876b042e2f3385d6
ToppCell10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD8_NK_sig-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CASP8 STK26

2.10e-03153202d8773ee16c7d3e0834b9f64054d42336d6f9833b
ToppCellControl-B_naive-1|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

MYH9 STK26

2.15e-031552020a78d1cab2bdba2dc8a74cdf35b5a0192370c4b5
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic-Neutrophil-Neu_c4-RSAD2|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

NVL SENP6

2.18e-03156202f5889a6899904dfb7f596600b3a76857cf9d5378
ToppCellfacs-Lung-ENDOMUCIN-18m-Lymphocytic-CD4-positive,_alpha-beta_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KDM2B STK26

2.37e-031632024af92b211d12c5b88b65bb746242cd702b545bd0
ToppCelldroplet-Kidney-nan-3m-Lymphocytic-NK_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STK26 CKAP2

2.37e-03163202eaed783eecd07aafa5af844b63c9d816b4da99e4
ToppCellfacs-Lung-ENDOMUCIN-18m-Lymphocytic-CD4+_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KDM2B STK26

2.37e-03163202d24774e0aa612322c22fdb3b314aef275fa01d68
ToppCelldroplet-Kidney-nan-3m-Lymphocytic-CD45____NK_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STK26 CKAP2

2.37e-03163202a763c1632d6465a1e753bdc8eadaf819d2b09e5e
ToppCell343B-Myeloid-Dendritic-cDC_activated|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

KDM2B RBM41

2.40e-03164202eae6d440877b292ad18dc4bd02802dda5b2f9c60
ToppCellPND14-Immune-Immune_Myeloid-Dendritic|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RBM41 CKAP2

2.52e-031682029b8a74abb83c64f0b5829dcb4275f722c82b45dc
ToppCellPND14-Immune-Immune_Myeloid-Dendritic-cDC1|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RBM41 CKAP2

2.52e-031682024b152b8d0f4a66faf664dfacb7914b18d60ce64a
ToppCellPND14-Immune-Immune_Myeloid-Dendritic-cDC1-cDC1_G2M|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RBM41 CKAP2

2.52e-03168202c3169ad8f4130ef18777ed86770bb722ffb5db85
ToppCell343B-Myeloid-Dendritic-cDC_activated|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

KDM2B RBM41

2.55e-03169202e68e6c24606fd46eca6f86bb63fa86ea17879ae2
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPEF2 CCDC190

2.55e-0316920214aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-NK-NK|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MYH9 SAMD9

2.58e-031702029a47d03f7eea6299a836a0eb1e7c1252c03f76df
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-NK|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MYH9 SAMD9

2.58e-031702020aa11d8cb44403b6769860dac2d3b05da6fff79d
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-NK-NK-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MYH9 SAMD9

2.58e-031702024252c0a335762508bd1f8f71c6e78a657d7df125
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-10|TCGA-Brain / Sample_Type by Project: Shred V9

SPEF2 CCDC190

2.61e-0317120274be8d3bf6b99e2d734635a8b1a7c41e8c596959
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-CD4_rest-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MYH9 STK26

2.61e-03171202e1fe07652c10c37191d1471ddaea500f74269e0c
ToppCellLPS-IL1RA-Lymphocytic_NKT-T_cells-T-cells|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CASP8 STK26

2.61e-03171202539ea88acc6f948efdeae8b69e5c5ffaee29f1d9
ToppCellControl-B_naive-1|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

MYH9 STK26

2.61e-03171202d18855b24aadea38fd1e4592f945cf15b85e05f1
ToppCellCiliated_cells-B-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

SPEF2 CCDC190

2.64e-03172202187ae91148d293537afc77e10da2b64302322224
ToppCellMild-CD4+_T_Exhausted|World / Disease group and Cell class

SPAG7 SAMD9

2.64e-03172202efe68d9477aa873b1637ee689f298120303aa322
ToppCellLPS-IL1RA-Lymphocytic_NKT-T_cells|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CASP8 STK26

2.64e-031722020fc692be845d4225ff8b63bf9195724fc8510c2c
ToppCellPND28-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NVL CTNNAL1

2.67e-0317320203b50b2376d353748a32bf14a9fc8341ea61dbca
ToppCellPND28-Endothelial-Endothelial_lymphatic|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NVL CTNNAL1

2.67e-031732022978c744d3c8dcaa2b9bb225abf846f82e8f9176
ToppCellPND28-Endothelial-Endothelial_lymphatic-Lymphatic_EC|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NVL CTNNAL1

2.67e-0317320212da47b90aecedaa31764ff7ddb853ee39123e9d
ToppCellPND28-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NVL CTNNAL1

2.67e-0317320223d4a315a0ad5c6fc77bcfc18b6c1ff55be99e8f
ToppCellPND07-28-samps-Epithelial-Epithelial-non_alveolar-Ciliated_cell_of_lung_parenchyma|PND07-28-samps / Age Group, Lineage, Cell class and subclass

SPEF2 CCDC190

2.70e-03174202f41d05a3703d7092bd3c4a97c15ae13069aaa4ad
ToppCellPND07-28-samps-Epithelial-Epithelial-non_alveolar|PND07-28-samps / Age Group, Lineage, Cell class and subclass

SPEF2 CCDC190

2.73e-03175202c01a15b2084da4a18f8ff3623f44eb9dfe499f10
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_26.46.91|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FBXO40 CTNNAL1

2.73e-031752023031f1eef3cfef8a7e5f57e567cb0868d06cac38
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-CD4_rest|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MYH9 STK26

2.73e-031752028269721389a3ce98681460e6393f2cff816eaa25
ToppCellLPS-antiTNF-Lymphocytic_NKT-T_cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CASP8 STK26

2.76e-03176202ea27e18407b8a13e8212830da859efeb8f158690
ToppCellLPS-IL1RA+antiTNF-Lymphocytic_NKT-T_cells|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CASP8 STK26

2.76e-03176202bb41e9478373726eb460af764de0277b2d09928e
ToppCellLPS-IL1RA+antiTNF-Lymphocytic_NKT-T_cells-T-cells|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CASP8 STK26

2.76e-031762029d4a4dfeebb5a8a0f3ab18c37c8ddc2cd2158575
ToppCellLPS-antiTNF-Lymphocytic_NKT-T_cells-T-cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CASP8 STK26

2.76e-03176202bfbab3c5b738b3b0b1540f2059d0245fbd8c0031
ToppCellNS-critical-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SPEF2 CCDC190

2.76e-03176202b794275fdd757b8fa2108e3c867f23da2649146d
ToppCellLPS-IL1RA+antiTNF-Lymphocytic_NKT|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CASP8 STK26

2.79e-03177202f1efd9c3074d5635700fe7fbebf3dd0b1e0a84f1
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

STK26 SAMD9

2.79e-03177202d3e6c768b88b7906f3c7fdd00ba20842212c14b1
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

STK26 SAMD9

2.79e-03177202f8f101c772c043636bedd6b2ec81409b1d2599bf
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

STK26 SAMD9

2.79e-03177202936ab2b180a052387124f68d0c7f41c0b164e748
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

STK26 SAMD9

2.79e-03177202d5aeda113afaa2425874394610344570c9078478
ToppCellControl|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SPEF2 CCDC190

2.79e-03177202b8ff6940e31b749776e81ae4f5bbd577dba9749c
ToppCellCOVID-19_Mild-Lymphoid_T/NK-NK_activated|COVID-19_Mild / Disease group, lineage and cell class

STK26 SAMD9

2.79e-031772026978a22fef40c8b455342373abe7593f5ede0fa4
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Hematopoietic-Megakaryocytic-Megakaryocyte-Mega|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RSU1 CTNNAL1

2.82e-031782025caeffb70cbb868586bd260b44ccd3751bbfa615
ToppCellControl-Lymphocytic_NKT-T_cells-T-cells|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CASP8 STK26

2.82e-03178202910f8bea19d335455aba24e6a07b4834b709db5d
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Hematopoietic-Megakaryocytic-Megakaryocyte|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RSU1 CTNNAL1

2.82e-031782022c581a338bf33dbd2be9abe87d0a84f97dfb546f
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Hematopoietic-Megakaryocytic|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RSU1 CTNNAL1

2.82e-03178202afc3220e2319cb38d59307db1b793a3915e1d5c4
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Hematopoietic|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RSU1 CTNNAL1

2.82e-031782024ff23a0bb20c4373db14bfaad18b5fa5c7c78e76
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPEF2 CCDC190

2.82e-031782023b12db04006db6e94fc45649a4b3a63b92f21a61
ToppCellPND28-Immune-Immune_Myeloid-Megakaryocyte/Platelet|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYH9 CTNNAL1

2.85e-03179202362c003503190dc272fa89185a83a65e063d7a67
ToppCellLPS-antiTNF-Lymphocytic_NKT|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CASP8 STK26

2.85e-03179202ecea75c568911ff56939c9f67ab901497bd4356c
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L2-3_LINC00507_RPL9P17|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MYH9 CTNNAL1

2.85e-031792029ba8693fba2175bca9ff9735cc04e657abeb9084
ToppCellPND28-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYH9 CTNNAL1

2.85e-03179202e0eec8d48868c76c3e879f219357c62ceff1bc76
ToppCellLPS-IL1RA-Lymphocytic_NKT|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CASP8 STK26

2.85e-031792025ccf0824611ded5c673d94dff3048aedac12f1a8
ToppCellControl-Lymphocytic_NKT-T_cells|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CASP8 STK26

2.85e-03179202d892d9496f1c33e23312092591eb2e968e736f7d
ToppCellPND28-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet-Megakaryocyte/Platelet_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYH9 CTNNAL1

2.85e-031792027d2e6bde00a9ab4cb21bd48b140ce205e36f9d77
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPEF2 CCDC190

2.88e-03180202adf5db5bfa9a38b1227ab0beccd8d6f3eea67ac0
ToppCellLPS_only-Lymphocytic_NKT-T_cells-T-cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CASP8 STK26

2.88e-03180202dcef253f2e97e4436b1b04e8a06a53ff6e64522c
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

CASP8 CCDC190

2.88e-03180202d9dae9db8e17f6990032ee6cfa8393fae4768ca5
ToppCell10x5'-Lung-Myeloid_Dendritic-migDC|Lung / Manually curated celltypes from each tissue

KDM2B CCDC190

2.88e-03180202e9e8992deb0beeee5548910e4616e7c990763d99
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPEF2 CCDC190

2.88e-031802021f1af4474f3f0ac3c0d6b1a6c875c354d36d8eec
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial-neuronal_stem_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTNNAL1 CKAP2

2.92e-031812024e81ec1580e9acb22c32c465eb46f83d1e9e424e
ToppCellLPS_only-Lymphocytic_NKT-T_cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CASP8 STK26

2.92e-03181202a4347ae554e6dcf03c7001a2b69332b377c7c034
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTNNAL1 CKAP2

2.92e-03181202ad30c01290fb98adbd0caed301a584761212c977
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTNNAL1 CKAP2

2.92e-031812023a3268a4dff8ffcb79e09f46490e138c96f8d916
ToppCellAdult-Epithelial-ciliated_cell-D122|Adult / Lineage, Cell type, age group and donor

SPEF2 CCDC190

2.95e-031822027ded554a4b441e6496db673ba206c0d76ccad7d9
ToppCelldroplet-Marrow-nan-3m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SENP6 STK26

2.95e-031822021710eab3037a87609d21838be2d2d29c3bc36651
ToppCelldroplet-Marrow-nan-3m-Hematologic-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SENP6 STK26

2.95e-03182202e78ba2c5cae480c16a596ce7c3bf2d480becacf4
ToppCellControl-Epithelial_cells-Airway_ciliated|Control / group, cell type (main and fine annotations)

SPEF2 CCDC190

2.95e-03182202fb725d10d9ed25dfc6d5bb69cfef78513f7d3e8f
ToppCellfacs-Skin-Skin_Anagen-18m-Epithelial-keratinocyte_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPEF2 CKAP2

2.95e-031822020fc45214f0b0766f69be6eff69cc4bec574023aa
ToppCellNS-critical-d_0-4-Lymphoid-Treg|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CASP8 CKAP2

2.98e-03183202f478dfa231fc1b12ead0183cc9d22077cdf43d1f
ToppCellBasal|World / shred by cell class for mouse tongue

RSU1 CTNNAL1

2.98e-03183202c6729a207526ff4aa48176207b9353176f631fea
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FBXO40 CKAP2

3.01e-03184202d1e0e3b0eed2db8a5b7e3d6f81294667e4ba64e5
ToppCellCerebellum-Macroglia|Cerebellum / BrainAtlas - Mouse McCarroll V32

SPEF2 CCDC190

3.01e-0318420291b047a01d2cad231308279ca37fa699630f7864
ToppCellCOVID-19_Severe-gd_T|COVID-19_Severe / Disease condition and Cell class

MYH9 STK26

3.01e-03184202791f1bcb954aadc63d4117c400537d036f68734d
ToppCellCOVID-19-Epithelial_cells-Airway_ciliated|COVID-19 / group, cell type (main and fine annotations)

SPEF2 CCDC190

3.04e-0318520218a40f0a338aa398d81384b5159fb80ce8a2020c
ToppCellControl-Lymphocytic_NKT|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CASP8 STK26

3.04e-0318520259d68e119f58b35bab36294758f6b2e25fd8f5c0
ToppCellCiliated_cells-B-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

SPEF2 CCDC190

3.04e-03185202f012c243343e1d1956db19b34d062e9b13de2b2a
ToppCell343B-Lymphocytic-CD4_T-cell-Treg_cell_1|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

SENP6 KDM2B

3.08e-0318620276cbc3610aedf8c19c17ad5faf6ef5e8980b6af5
ToppCellP28-Epithelial-airway_epithelial_cell-club_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SPEF2 CCDC190

3.08e-03186202a26811481668fa25c48a064a56c198685693ad8d
ToppCellP28-Epithelial-airway_epithelial_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SPEF2 CCDC190

3.08e-03186202df80f101954b8ec6ccdb03e702de22e70b65181f
ToppCellControl-Endothelial-Endothelial-Vein|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SPEF2 CTNNAL1

3.08e-0318620292092f11ecce22c14f244e42c499af0822977e6f
ToppCell21-Trachea-Epithelial-Intermediate_ciliated|Trachea / Age, Tissue, Lineage and Cell class

SPEF2 CCDC190

3.11e-031872021a2178a195d078d1963947b327c6d0d4f2f48341
ToppCelltumor_Lung-Epithelial_cells-tS3|Epithelial_cells / Location, Cell class and cell subclass

SPEF2 KIF3A

3.11e-031872023cea677279e71fdb9879530dea10a5e6393beacd
ToppCellPND03|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYH9 SPEF2

3.11e-03187202b3fcb36d853adfdea7172c5591de06f027e50af3
ToppCellP15-Epithelial-airway_epithelial_cell-club_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SPEF2 CCDC190

3.11e-03187202a70aaae32426e9ddb1cbfbd0e0db24ccc96b9f40
ToppCellAdult-Epithelial-ciliated_cell-D231|Adult / Lineage, Cell type, age group and donor

SPEF2 CCDC190

3.14e-0318820234b11f72ca73153d02edcd09b38983ad1a504659

Protein segments in the cluster

PeptideGeneStartEntry
KMKNKQLPSAGPDKN

ENSA

76

O43768
KMNTANPERKPKKNQ

DOT1L

416

Q8TEK3
TEKQKQDANMPKKPV

CKAP2

161

Q8WWK9
EPQKKNKGDPMNNLE

RBM41

176

Q96IZ5
QQKKNPEMEDLPSKG

NVL

496

O15381
GETLNNKDSKQKMPP

KIAA1107

416

Q9UPP5
KDPMKSKKQPLSQNN

CCDC190

131

Q86UF4
KVNKDDIQKMNPPKF

MYH9

66

P35579
GNNMRKQTPVPDKKE

KIF3A

626

Q9Y496
QKMNRDNKEGQEPAK

KDM2B

751

Q8NHM5
KPMKNNANLKSLKPD

CTNNAL1

541

Q9UBT7
SNKDDKKNMGKQMPQ

CASP8

451

Q14790
EGAPKKKEPQENQKQ

FBXO40

261

Q9UH90
QANPEPPKKNNDKSK

RSU1

251

Q15404
ADPKEKSPQMGANKK

SPEF2

1286

Q9C093
QDSGQIKKKFQPMNK

SPAG7

61

O75391
KKPDPKKVQNGAEQD

STK26

331

Q9P289
KQKQKGKENPDMANP

SAMD9

111

Q5K651
QQMLNFPDKGKEKPT

SMARCC2

556

Q8TAQ2
KAIDDNQEMPPNKKK

THOC2

911

Q8NI27
KDVMKGSNPKVPQQN

SENP6

1011

Q9GZR1