Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontestosterone 16-alpha-hydroxylase activity

CYP3A4 CYP3A5 CYP3A43

2.24e-0641663GO:0008390
GeneOntologyMolecularFunctiontestosterone 6-beta-hydroxylase activity

CYP3A4 CYP3A5 CYP3A43

5.57e-0651663GO:0050649
GeneOntologyMolecularFunctionvitamin D 23-hydroxylase activity

CYP3A4 CYP3A5 CYP3A43

5.57e-0651663GO:0062179
GeneOntologyMolecularFunction1-alpha,25-dihydroxyvitamin D3 23-hydroxylase activity

CYP3A4 CYP3A5 CYP3A43

5.57e-0651663GO:0062181
GeneOntologyMolecularFunctionmicrotubule binding

DCDC1 EML4 EML6 DYSF MAP10 TUBGCP6 NEFH NF1 RMDN1 ABRAXAS1 MACF1 DYNC1I1

1.07e-0530816612GO:0008017
GeneOntologyMolecularFunctionvitamin D3 25-hydroxylase activity

CYP3A4 CYP3A5 CYP3A43

1.11e-0561663GO:0030343
GeneOntologyMolecularFunctionvitamin D 24-hydroxylase activity

CYP3A4 CYP3A5 CYP3A43

1.11e-0561663GO:0070576
GeneOntologyMolecularFunctionvitamin D 25-hydroxylase activity

CYP3A4 CYP3A5 CYP3A43

1.93e-0571663GO:0070643
GeneOntologyMolecularFunctionoxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor

CYP3A4 CYP3A5 CYP3A43

3.06e-0581663GO:0033695
GeneOntologyMolecularFunctioncaffeine oxidase activity

CYP3A4 CYP3A5 CYP3A43

3.06e-0581663GO:0034875
GeneOntologyMolecularFunctionestrogen 2-hydroxylase activity

CYP3A4 CYP3A5 CYP3A43

3.06e-0581663GO:0101021
GeneOntologyMolecularFunctionestrogen 16-alpha-hydroxylase activity

CYP3A4 CYP3A5 CYP3A43

8.86e-05111663GO:0101020
GeneOntologyMolecularFunctioncytoskeletal protein binding

DCDC1 SYNM MYO9B EML4 EML6 DYSF MAP10 ABLIM3 TUBGCP6 SPTBN4 SPTBN5 NEFH NF1 DLC1 LMO7 RMDN1 ABRAXAS1 SYNE2 MACF1 SNTA1 DYNC1I1 FRMD3

1.18e-04109916622GO:0008092
GeneOntologyMolecularFunctionGTPase activator activity

MYO9B TBC1D8B RGS7 RGS12 RGS8 NF1 DLC1 TBC1D14 ARHGAP21 ARAP1

1.18e-0427916610GO:0005096
GeneOntologyMolecularFunctionretinoic acid 4-hydroxylase activity

CYP3A4 CYP3A5 CYP3A43

1.92e-04141663GO:0008401
GeneOntologyMolecularFunctionoxidoreductase activity, acting on CH or CH2 groups

CYP3A4 CYP3A5 CYP3A43

2.39e-04151663GO:0016725
GeneOntologyMolecularFunctiondynein intermediate chain binding

DNAH1 SPTBN5 DNAH17 DYNC1H1

2.46e-04371664GO:0045505
GeneOntologyMolecularFunctiontubulin binding

DCDC1 EML4 EML6 DYSF MAP10 TUBGCP6 NEFH NF1 RMDN1 ABRAXAS1 MACF1 DYNC1I1

2.52e-0442816612GO:0015631
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

IQSEC3 MYO9B TBC1D8B RGS7 RGS12 RGS8 NF1 DLC1 SBF1 TBC1D14 HERC2 ARHGAP21 ARAP1

3.30e-0450716613GO:0060589
GeneOntologyMolecularFunctionGTPase regulator activity

IQSEC3 MYO9B TBC1D8B RGS7 RGS12 RGS8 NF1 DLC1 SBF1 TBC1D14 HERC2 ARHGAP21 ARAP1

3.30e-0450716613GO:0030695
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH1 DNAH17 DYNC1H1

4.20e-04181663GO:0008569
GeneOntologyMolecularFunctionhigh-affinity L-glutamate transmembrane transporter activity

SLC1A3 SLC1A6

6.76e-0451662GO:0005314
GeneOntologyMolecularFunctionglutamate:sodium symporter activity

SLC1A3 SLC1A6

6.76e-0451662GO:0015501
GeneOntologyMolecularFunctionpeptide hormone binding

PRLHR GALR3 PTH2R HCRTR1

1.13e-03551664GO:0017046
GeneOntologyMolecularFunctionenzyme activator activity

WDR4 MYO9B GPRC5A TBC1D8B RGS7 RGS12 MMP24 RGS8 NF1 DLC1 TBC1D14 CDC20 ARHGAP21 ARAP1

1.19e-0365616614GO:0008047
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DNAH1 DNAH17 DYNC1H1

1.59e-03281663GO:0051959
GeneOntologyBiologicalProcessvesicle cargo loading

CTAGE9 MIA3 CTAGE6 CTAGE8 CTAGE15 CTAGE4

4.10e-07361676GO:0035459
GeneOntologyBiologicalProcessalkaloid catabolic process

CYP3A4 CYP3A5 CYP3A43

5.15e-0651673GO:0009822
GeneOntologyBiologicalProcessGolgi vesicle transport

CTAGE9 MIA3 CTAGE6 COG8 EXOC8 SLC30A6 CTAGE8 TBC1D14 CTAGE15 MACF1 EXOC1 CTAGE4

2.15e-0533916712GO:0048193
GeneOntologyBiologicalProcessL-glutamate import

CLN8 SLC1A3 SLC1A6 NF1 ABCC8

3.43e-05461675GO:0051938
GeneOntologyBiologicalProcessalkaloid metabolic process

CYP3A4 CYP3A5 CYP3A43

4.23e-0591673GO:0009820
GeneOntologyBiologicalProcesslipid hydroxylation

CYP3A4 CYP3A5 CYP3A43

4.23e-0591673GO:0002933
GeneOntologyBiologicalProcesspositive regulation of uterine smooth muscle relaxation

NPPC ABCC8

6.52e-0521672GO:1900721
GeneOntologyBiologicalProcessregulation of uterine smooth muscle relaxation

NPPC ABCC8

6.52e-0521672GO:1900719
GeneOntologyBiologicalProcessuterine smooth muscle relaxation

NPPC ABCC8

6.52e-0521672GO:0044558
GeneOntologyBiologicalProcessoxidative demethylation

CYP3A4 CYP3A5 CYP3A43

1.09e-04121673GO:0070989
GeneOntologyBiologicalProcessintermediate filament cytoskeleton organization

CLN8 KRT26 KRT16 SYNM NEFH MACF1

1.55e-04991676GO:0045104
GeneOntologyBiologicalProcessintermediate filament-based process

CLN8 KRT26 KRT16 SYNM NEFH MACF1

1.64e-041001676GO:0045103
GeneOntologyBiologicalProcesspositive regulation of relaxation of smooth muscle

NPPC ABCC8

1.94e-0431672GO:1901082
GeneOntologyBiologicalProcesstight junction disassembly

TGFB3 ABCC8

1.94e-0431672GO:1905071
GeneOntologyBiologicalProcesspositive regulation of tight junction disassembly

TGFB3 ABCC8

1.94e-0431672GO:1905075
GeneOntologyBiologicalProcessregulation of tight junction disassembly

TGFB3 ABCC8

1.94e-0431672GO:1905073
GeneOntologyBiologicalProcessmicrotubule cytoskeleton organization

EML4 DYSF MAP10 KIAA0753 DNAH1 TUBGCP6 NEFH RMDN1 ABRAXAS1 DNAH17 SYNE2 PAX6 CDC20 DYNC1H1 MOS BBOF1

2.57e-0472016716GO:0000226
GeneOntologyCellularComponentendoplasmic reticulum exit site

CTAGE9 MIA3 CTAGE6 CTAGE8 CTAGE15 CTAGE4

1.09e-06421706GO:0070971
GeneOntologyCellularComponentpolymeric cytoskeletal fiber

KRT26 KRT16 DCDC1 NCKAP1 SYNM MYO9B EML4 EML6 TPGS2 DYSF MAP10 DNAH1 TUBGCP6 SPTBN4 NEFH DLC1 RMDN1 DNAH17 MACF1 DYNC1H1 DYNC1I1

1.38e-0589917021GO:0099513
GeneOntologyCellularComponentsupramolecular fiber

KRT26 KRT16 DCDC1 NCKAP1 SYNM MYO9B EML4 EML6 TPGS2 DYSF MAP10 RYR2 DNAH1 TUBGCP6 SPTBN4 NEFH DLC1 RMDN1 DNAH17 SYNE2 MACF1 DYNC1H1 DYNC1I1

8.75e-05117917023GO:0099512
GeneOntologyCellularComponentsupramolecular polymer

KRT26 KRT16 DCDC1 NCKAP1 SYNM MYO9B EML4 EML6 TPGS2 DYSF MAP10 RYR2 DNAH1 TUBGCP6 SPTBN4 NEFH DLC1 RMDN1 DNAH17 SYNE2 MACF1 DYNC1H1 DYNC1I1

9.68e-05118717023GO:0099081
GeneOntologyCellularComponentmicrotubule

DCDC1 EML4 EML6 TPGS2 DYSF MAP10 DNAH1 TUBGCP6 RMDN1 DNAH17 MACF1 DYNC1H1 DYNC1I1

4.34e-0453317013GO:0005874
DomainCyt_P450_E_grp-II

CYP3A4 CYP3A5 CYP3A43

6.21e-0651613IPR002402
DomainCyt_P450_E_CYP3A

CYP3A4 CYP3A5 CYP3A43

1.23e-0561613IPR008072
DomainWD40_repeat

WDR4 EML4 EML6 WSB2 WDFY4 ERCC8 MIOS HERC2 MAPKBP1 CDC20 DYNC1I1

2.47e-0527216111IPR001680
DomainWD_REPEATS_1

WDR4 EML4 EML6 WSB2 WDFY4 ERCC8 MIOS HERC2 MAPKBP1 CDC20 DYNC1I1

3.02e-0527816111PS00678
DomainWD_REPEATS_2

WDR4 EML4 EML6 WSB2 WDFY4 ERCC8 MIOS HERC2 MAPKBP1 CDC20 DYNC1I1

3.12e-0527916111PS50082
DomainWD_REPEATS_REGION

WDR4 EML4 EML6 WSB2 WDFY4 ERCC8 MIOS HERC2 MAPKBP1 CDC20 DYNC1I1

3.12e-0527916111PS50294
DomainSpectrin

SPTBN4 SPTBN5 SYNE2 MACF1

4.15e-05231614PF00435
DomainACTININ_2

SPTBN4 SPTBN5 SYNE2 MACF1

4.15e-05231614PS00020
DomainACTININ_1

SPTBN4 SPTBN5 SYNE2 MACF1

4.15e-05231614PS00019
DomainActinin_actin-bd_CS

SPTBN4 SPTBN5 SYNE2 MACF1

4.15e-05231614IPR001589
DomainSpectrin_repeat

SPTBN4 SPTBN5 SYNE2 MACF1

1.07e-04291614IPR002017
DomainWD40

WDR4 EML4 EML6 WSB2 WDFY4 ERCC8 MIOS MAPKBP1 CDC20 DYNC1I1

1.14e-0426816110SM00320
DomainSPEC

SPTBN4 SPTBN5 SYNE2 MACF1

1.58e-04321614SM00150
DomainSpectrin/alpha-actinin

SPTBN4 SPTBN5 SYNE2 MACF1

1.58e-04321614IPR018159
DomainCH

SPTBN4 SPTBN5 LMO7 SYNE2 MACF1

2.43e-04651615SM00033
DomainWD40_repeat_dom

WDR4 EML4 EML6 WSB2 WDFY4 ERCC8 MIOS MAPKBP1 CDC20 DYNC1I1

2.61e-0429716110IPR017986
DomainPH_dom-like

CDC42BPG IQSEC3 WDFY4 RGS12 EXOC8 SPTBN4 SPTBN5 SBF1 ARHGAP21 SNTA1 ARAP1 FRMD3

3.32e-0442616112IPR011993
DomainCH

SPTBN4 SPTBN5 LMO7 SYNE2 MACF1

3.45e-04701615PF00307
Domain-

SPTBN4 SPTBN5 LMO7 SYNE2 MACF1

3.68e-047116151.10.418.10
DomainCH

SPTBN4 SPTBN5 LMO7 SYNE2 MACF1

4.19e-04731615PS50021
DomainWD40

WDR4 EML4 EML6 WSB2 WDFY4 ERCC8 MAPKBP1 CDC20 DYNC1I1

4.22e-042591619PF00400
DomainCH-domain

SPTBN4 SPTBN5 LMO7 SYNE2 MACF1

4.75e-04751615IPR001715
Domain-

WDR4 EML4 EML6 WSB2 WDFY4 ERCC8 MIOS MAPKBP1 CDC20 DYNC1I1

6.40e-04333161102.130.10.10
DomainWD40/YVTN_repeat-like_dom

WDR4 EML4 EML6 WSB2 WDFY4 ERCC8 MIOS MAPKBP1 CDC20 DYNC1I1

6.70e-0433516110IPR015943
DomainPH

CDC42BPG IQSEC3 EXOC8 SPTBN4 SPTBN5 SBF1 ARHGAP21 SNTA1 ARAP1

7.02e-042781619SM00233
DomainPH_DOMAIN

CDC42BPG IQSEC3 EXOC8 SPTBN4 SPTBN5 SBF1 ARHGAP21 SNTA1 ARAP1

7.20e-042791619PS50003
DomainPH_domain

CDC42BPG IQSEC3 EXOC8 SPTBN4 SPTBN5 SBF1 ARHGAP21 SNTA1 ARAP1

7.39e-042801619IPR001849
DomainPH

CDC42BPG EXOC8 SPTBN4 SPTBN5 SBF1 ARHGAP21 SNTA1 ARAP1

8.51e-042291618PF00169
Domain-

RGS7 RGS12 RGS8

8.58e-042216131.10.196.10
DomainRGS_subdom1

RGS7 RGS12 RGS8

8.58e-04221613IPR024066
DomainRho_GTPase_activation_prot

MYO9B NF1 DLC1 ARHGAP21 ARAP1

9.85e-04881615IPR008936
DomainHELP

EML4 EML6

1.08e-0361612PF03451
DomainHELP

EML4 EML6

1.08e-0361612IPR005108
DomainNA_DICARBOXYL_SYMP_1

SLC1A3 SLC1A6

1.51e-0371612PS00713
DomainNA_DICARBOXYL_SYMP_2

SLC1A3 SLC1A6

1.51e-0371612PS00714
DomainSDF

SLC1A3 SLC1A6

1.51e-0371612PF00375
Domain-

SLC1A3 SLC1A6

1.51e-03716121.10.3860.10
DomainNa-dicarboxylate_symporter

SLC1A3 SLC1A6

1.51e-0371612IPR001991
DomainNa-dicarboxylate_symporter_CS

SLC1A3 SLC1A6

1.51e-0371612IPR018107
PathwayBIOCARTA_ACETAMINOPHEN_PATHWAY

CYP3A4 CYP3A5 CYP3A43

4.05e-0581293MM1547
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

GPC1 IQSEC3 PDE1C KRT16 NCKAP1 PRR36 WFS1 PLD3 PFKP ABLIM3 SLC1A3 NDUFS8 SPTBN4 NEFH NF1 SBF1 LMO7 AJM1 MIOS PRKAR1A MACF1 EXOC1 ARHGAP21 SNTA1 DYNC1H1 DYNC1I1

8.15e-0914311702637142655
Pubmed

Downregulation of mouse hepatic CYP3A protein by 3-methylcholanthrene does not require cytochrome P450-dependent metabolism.

CYP3A4 CYP3A5 CYP3A43

1.15e-073170323846873
Pubmed

Regulation of the expression of two female-predominant CYP3A mRNAs (CYP3A41 and CYP3A44) in mouse liver by sex and growth hormones.

CYP3A4 CYP3A5 CYP3A43

1.15e-073170312147261
Pubmed

Mouse liver cytochrome P-450 (P-450IIIAM1): its cDNA cloning and inducibility by dexamethasone.

CYP3A4 CYP3A5 CYP3A43

1.15e-07317031339292
Pubmed

Predominantly neuronal expression of cytochrome P450 isoforms CYP3A11 and CYP3A13 in mouse brain.

CYP3A4 CYP3A5 CYP3A43

1.15e-073170312617959
Pubmed

Intergenic mRNA molecules resulting from trans-splicing.

CYP3A4 CYP3A5 CYP3A43

1.15e-073170311726664
Pubmed

High fat diet induced obesity is mitigated in Cyp3a-null female mice.

CYP3A4 CYP3A5 CYP3A43

1.15e-073170329738703
Pubmed

A novel female-specific member of the CYP3A gene subfamily in the mouse liver.

CYP3A4 CYP3A5 CYP3A43

1.15e-073170310775455
Pubmed

Concordant up-regulation of cytochrome P450 Cyp3a11, testosterone oxidation and androgen receptor expression in mouse brain after xenobiotic treatment.

CYP3A4 CYP3A5 CYP3A43

1.15e-073170319226368
Pubmed

Dynamic patterns of histone methylation are associated with ontogenic expression of the Cyp3a genes during mouse liver maturation.

CYP3A4 CYP3A5 CYP3A43

1.15e-073170319188337
Pubmed

Human gut microbiota influences drug-metabolizing enzyme hepatic Cyp3a: A human flora-associated mice study.

CYP3A4 CYP3A5 CYP3A43

1.15e-073170337258238
Pubmed

Effect of Naringenin, Quercetin, and Sesamin on Xenobiotica-Metabolizing CYP1A and CYP3A in Mice Offspring after Maternal Exposure to Persistent Organic Pollutants.

CYP3A4 CYP3A5 CYP3A43

1.15e-073170328567424
Pubmed

A useful model capable of predicting the clearance of cytochrome 3A4 (CYP3A4) substrates in humans: validity of CYP3A4 transgenic mice lacking their own Cyp3a enzymes.

CYP3A4 CYP3A5 CYP3A43

1.15e-073170325005602
Pubmed

Cloning, sequencing, heterologous expression, and characterization of murine cytochrome P450 3a25*(Cyp3a25), a testosterone 6beta-hydroxylase.

CYP3A4 CYP3A5 CYP3A43

1.15e-073170311284050
Pubmed

Collaborated regulation of female-specific murine Cyp3a41 gene expression by growth and glucocorticoid hormones.

CYP3A4 CYP3A5 CYP3A43

1.15e-073170314733933
Pubmed

Genetic variations in androgen metabolism genes and associations with prostate cancer in South African men.

CYP3A4 CYP3A5 CYP3A43

1.15e-073170321081028
Pubmed

Mouse cytochrome P450 (Cyp3a11): predominant expression in liver and capacity to activate aflatoxin B1.

CYP3A4 CYP3A5 CYP3A43

1.15e-07317039143324
Pubmed

Lentiviral transgenic microRNA-based shRNA suppressed mouse cytochromosome P450 3A (CYP3A) expression in a dose-dependent and inheritable manner.

CYP3A4 CYP3A5 CYP3A43

1.15e-073170322291988
Pubmed

CYP3A4, CYP3A5, and CYP3A43 genotypes and haplotypes in the etiology and severity of prostate cancer.

CYP3A4 CYP3A5 CYP3A43

1.15e-073170315548719
Pubmed

CYP3A-mediated generation of aldehyde and hydrazine in atazanavir metabolism.

CYP3A4 CYP3A5 CYP3A43

1.15e-073170321148252
Pubmed

Different diets cause alterations in the enteric environment and trigger changes in the expression of hepatic cytochrome P450 3A, a drug-metabolizing enzyme.

CYP3A4 CYP3A5 CYP3A43

1.15e-073170323370405
Pubmed

Selective inactivation of mouse liver cytochrome P-450IIIA by cannabidiol.

CYP3A4 CYP3A5 CYP3A43

1.15e-07317032402224
Pubmed

Genetic analysis of sensitization and tolerance to cocaine.

CYP3A4 CYP3A5 CYP3A43

1.15e-07317037932176
Pubmed

Metabolomics reveals the formation of aldehydes and iminium in gefitinib metabolism.

CYP3A4 CYP3A5 CYP3A43

1.15e-073170326212543
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

IQSEC3 MIA3 NCKAP1 PRR36 ABLIM3 SLC1A3 SPTBN4 NEFH FRY NF1 SBF1 SYNE2 MIOS PRKAR1A MACF1 HERC2 TOP3B ARHGAP21 DYNC1H1

2.89e-079631701928671696
Pubmed

Hepatocyte nuclear factor 4α regulates expression of the mouse female-specific Cyp3a41 gene in the liver.

CYP3A4 CYP3A5 CYP3A43

4.57e-074170321088200
Pubmed

Humanized liver TK-NOG mice with functional deletion of hepatic murine cytochrome P450s as a model for studying human drug metabolism.

CYP3A4 CYP3A5 CYP3A43

4.57e-074170336050438
Pubmed

A novel form of mouse cytochrome P450 3A (Cyp3a-16). Its cDNA cloning and expression in fetal liver.

CYP3A4 CYP3A5 CYP3A43

4.57e-07417037813478
Pubmed

Knockout of cytochrome P450 3A yields new mouse models for understanding xenobiotic metabolism.

CYP3A4 CYP3A5 CYP3A43

4.57e-074170317975676
Pubmed

Bmal1 regulates circadian expression of cytochrome P450 3a11 and drug metabolism in mice.

CYP3A4 CYP3A5 CYP3A43

4.57e-074170331633069
Pubmed

Cyp2c70 is responsible for the species difference in bile acid metabolism between mice and humans.

CYP3A4 CYP3A5 CYP3A43

4.57e-074170327638959
Pubmed

Humanized xenobiotic response in mice expressing nuclear receptor SXR.

CYP3A4 CYP3A5 CYP3A43

4.57e-074170310935643
Pubmed

Knockout of mouse Cyp3a gene enhances synthesis of cholesterol and bile acid in the liver.

CYP3A4 CYP3A5 CYP3A43

4.57e-074170323709690
Pubmed

Thalidomide-induced limb abnormalities in a humanized CYP3A mouse model.

CYP3A4 CYP3A5 CYP3A43

4.57e-074170326903378
Pubmed

iTAG-RNA Isolates Cell-Specific Transcriptional Responses to Environmental Stimuli and Identifies an RNA-Based Endocrine Axis.

CYP3A4 CYP3A5 CYP3A43

4.57e-074170332130917
Pubmed

CYP3A4 and pregnane X receptor humanized mice.

CYP3A4 CYP3A5 CYP3A43

4.57e-074170317936928
Pubmed

Genomic characterization and regulation of CYP3a13: role of xenobiotics and nuclear receptors.

CYP3A4 CYP3A5 CYP3A43

4.57e-074170312958193
Pubmed

Unchanged cytochrome P450 3A (CYP3A) expression and metabolism of midazolam, triazolam, and dexamethasone in mdr(-/-) mouse liver microsomes.

CYP3A4 CYP3A5 CYP3A43

4.57e-074170310230766
Pubmed

Schisandrol B protects against acetaminophen-induced hepatotoxicity by inhibition of CYP-mediated bioactivation and regulation of liver regeneration.

CYP3A4 CYP3A5 CYP3A43

4.57e-074170325319358
Pubmed

The transcription factor E4bp4 regulates the expression and activity of Cyp3a11 in mice.

CYP3A4 CYP3A5 CYP3A43

4.57e-074170330796914
Pubmed

Mouse aortic muscle cells respond to oxygen following cytochrome P450 3A13 gene transfer.

CYP3A4 CYP3A5 CYP3A43

4.57e-074170323656416
Pubmed

Molecular cloning and functional expression of a mouse cytochrome P-450 (Cyp3a-13): examination of Cyp3a-13 enzyme to activate aflatoxin B1 (AFB1).

CYP3A4 CYP3A5 CYP3A43

4.57e-07417037803471
Pubmed

A map of the mouse Cyp3a locus.

CYP3A4 CYP3A5 CYP3A43

4.57e-074170314509827
Pubmed

Trans-chromosomic mice containing a human CYP3A cluster for prediction of xenobiotic metabolism in humans.

CYP3A4 CYP3A5 CYP3A43

4.57e-074170323125282
Pubmed

Cell-Type-Specific Alternative Splicing Governs Cell Fate in the Developing Cerebral Cortex.

EML4 SYNE2 MACF1 PAX6 ARHGAP21

1.01e-0637170527565344
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

EXOSC10 MIA3 NDUFAF2 SYNM WFS1 DNAJC30 ANKRD26 DNAJC27 PFAS PLD3 PFKP NDUFS8 KIAA0753 TUBGCP6 URB1 SBF1 SYNE2 ASCC2 PRKAR1A EIF5B MACF1 HERC2 TOP3B

1.08e-0614871702333957083
Pubmed

Sterol 27-hydroxylase gene dosage and the antiatherosclerotic effect of Rifampicin in mice.

CYP3A4 CYP3A5 CYP3A43

1.14e-065170329191818
Pubmed

Genomic organization of the human CYP3A locus: identification of a new, inducible CYP3A gene.

CYP3A4 CYP3A5 CYP3A43

1.14e-065170311266076
Pubmed

Absence of both cytochrome P450 3A and P-glycoprotein dramatically increases docetaxel oral bioavailability and risk of intestinal toxicity.

CYP3A4 CYP3A5 CYP3A43

1.14e-065170319920203
Pubmed

Hepatic and hippocampal cytochrome P450 enzyme overexpression during spontaneous recurrent seizures.

CYP3A4 CYP3A5 CYP3A43

1.14e-065170329125184
Pubmed

P-glycoprotein and cytochrome P450 3A act together in restricting the oral bioavailability of paclitaxel.

CYP3A4 CYP3A5 CYP3A43

1.14e-065170323090875
Pubmed

Multiple cytochrome P450 isozymes in murine skin: induction of P450 1A, 2B, 2E, and 3A by dexamethasone.

CYP3A4 CYP3A5 CYP3A43

1.14e-06517038006463
Pubmed

Glycine N-methyltransferase inhibits aristolochic acid nephropathy by increasing CYP3A44 and decreasing NQO1 expression in female mouse hepatocytes.

CYP3A4 CYP3A5 CYP3A43

1.14e-065170329725048
Pubmed

Midazolam metabolism in cytochrome P450 3A knockout mice can be attributed to up-regulated CYP2C enzymes.

CYP3A4 CYP3A5 CYP3A43

1.14e-065170318156313
Pubmed

OATP1A/1B, CYP3A, ABCB1, and ABCG2 limit oral availability of the NTRK inhibitor larotrectinib, while ABCB1 and ABCG2 also restrict its brain accumulation.

CYP3A4 CYP3A5 CYP3A43

1.14e-065170332087611
Pubmed

Characterization and expression pattern of the novel MIA homolog TANGO.

CTAGE9 MIA3 CTAGE8

1.14e-065170315183315
Pubmed

Zinc Fingers and Homeoboxes 2 (Zhx2) Regulates Sexually Dimorphic Cyp Gene Expression in the Adult Mouse Liver.

CYP3A4 CYP3A5 CYP3A43 ZHX2

1.25e-0617170427197076
Pubmed

Induction and genetic regulation of mouse hepatic cytochrome P450 by cannabidiol.

CYP3A4 CYP3A5 CYP3A43

2.27e-06617038043019
Pubmed

Defining Human Pathways of Drug Metabolism In Vivo through the Development of a Multiple Humanized Mouse Model.

CYP3A4 CYP3A5 CYP3A43

2.27e-066170326265742
Pubmed

Cytochrome P-450 3A13 and endothelin jointly mediate ductus arteriosus constriction to oxygen in mice.

CYP3A4 CYP3A5 CYP3A43

2.27e-066170321193583
Pubmed

Activated sterol regulatory element-binding protein-2 suppresses hepatocyte nuclear factor-4-mediated Cyp3a11 expression in mouse liver.

CYP3A4 CYP3A5 CYP3A43

2.27e-066170320926756
Pubmed

Individual and combined roles of CYP3A, P-glycoprotein (MDR1/ABCB1) and MRP2 (ABCC2) in the pharmacokinetics of docetaxel.

CYP3A4 CYP3A5 CYP3A43

2.27e-066170321351274
Pubmed

Opposing regulation of cytochrome P450 expression by CAR and PXR in hypothyroid mice.

CYP3A4 CYP3A5 CYP3A43

2.27e-066170322503787
Pubmed

Upregulation of CYP2e1 and CYP3a activities in histamine-deficient histidine decarboxylase gene targeted mice.

CYP3A4 CYP3A5 CYP3A43

2.27e-066170314642533
Pubmed

LXR deficiency and cholesterol feeding affect the expression and phenobarbital-mediated induction of cytochromes P450 in mouse liver.

CYP3A4 CYP3A5 CYP3A43

2.27e-066170315930522
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

KRT16 WDR4 EML6 ANKRD26 CTAGE6 PFKP PLA2G4D RYR2 SPTBN4 RIMKLB CLCN5 LMO7 SYNE2 CTAGE8 EIF5B CTAGE15 MACF1 CTAGE4 TOP3B ARHGAP21 DYNC1I1 BBOF1

2.36e-0614421702235575683
Pubmed

The human cytochrome P450 3A locus. Gene evolution by capture of downstream exons.

CYP3A4 CYP3A5 CYP3A43

3.96e-067170311137287
Pubmed

Cyp3a deficiency enhances androgen receptor activity and cholesterol synthesis in the mouse prostate.

CYP3A4 CYP3A5 CYP3A43

3.96e-067170327137100
Pubmed

Joint effects of inflammation and androgen metabolism on prostate cancer severity.

CYP3A4 CYP3A5 CYP3A43

3.96e-067170318566991
Pubmed

Effects of infection of MRSA on the expression and activity of renal cytochrome P450s in mice.

CYP3A4 CYP3A5 CYP3A43

3.96e-067170330944282
Pubmed

Cyp3a11-mediated testosterone-6β-hydroxylation decreased, while UGT1a9-mediated propofol O-glucuronidation increased, in mice with diabetes mellitus.

CYP3A4 CYP3A5 CYP3A43

3.96e-067170327514509
Pubmed

A novel transmembrane MSP-containing protein that plays a role in right ventricle development.

CYP3A4 CYP3A5 CYP3A43

3.96e-067170315533722
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

WDR4 SYNM LONRF1 RFX5 MSTO1 SPTBN4 FRY LMO7 PRKAR1A LRP4 MACF1 ASTN1 EXOC1 PAX6 HERC2 MERTK ARHGAP21 SNTA1 DYNC1H1 DYNC1I1

5.26e-0612851702035914814
Pubmed

Identification and characterization of human FNBP3 gene in silico.

CYP3A4 CYP3A5 CYP3A43

6.31e-068170312964049
Pubmed

Drug metabolizing enzyme induction pathways in experimental non-alcoholic steatohepatitis.

CYP3A4 CYP3A5 CYP3A43

6.31e-068170318488193
Pubmed

Intestinal cytochrome P450 3A plays an important role in the regulation of detoxifying systems in the liver.

CYP3A4 CYP3A5 CYP3A43

6.31e-068170318794335
Pubmed

An Extensively Humanized Mouse Model to Predict Pathways of Drug Disposition and Drug/Drug Interactions, and to Facilitate Design of Clinical Trials.

CYP3A4 CYP3A5 CYP3A43

6.31e-068170330910785
Pubmed

Chromosomal assignments of genes coding for components of the mixed-function oxidase system in mice. Genetic localization of the cytochrome P-450PCN and P-450PB gene families and the nadph-cytochrome P-450 oxidoreductase and epoxide hydratase genes.

CYP3A4 CYP3A5 CYP3A43

9.43e-06917033917435
Pubmed

The P450 superfamily: update on new sequences, gene mapping, accession numbers, early trivial names of enzymes, and nomenclature.

CYP3A4 CYP3A5 CYP3A43

9.43e-06917037678494
Pubmed

The duality of beta-catenin function: a requirement in lens morphogenesis and signaling suppression of lens fate in periocular ectoderm.

LRP6 PAX1 PAX6

9.43e-069170316102745
Pubmed

Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.

NCKAP1 WFS1 ABLIM3 SLC1A3 NEFH NF1 SBF1 MACF1 HERC2 ARHGAP21 SNTA1

9.66e-064301701132581705
Pubmed

Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

SYNM PFAS ZFYVE26 HERC2 DYNC1H1 ZNF646

1.27e-0510417069205841
Pubmed

Liver maturation deficiency in p57(Kip2)-/- mice occurs in a hepatocytic p57(Kip2) expression-independent manner.

CYP3A4 CYP3A5 CYP3A43

1.34e-0510170326165599
Pubmed

140 mouse brain proteins identified by Ca2+-calmodulin affinity chromatography and tandem mass spectrometry.

NCKAP1 PFKP SPTBN4 NF1 SBF1 DYNC1H1 DYNC1I1

1.65e-05163170716512683
Pubmed

Role of the Drug-Metabolizing Enzyme CYP during Mouse Liver Development.

CYP3A4 CYP3A5 CYP3A43

1.84e-0511170327904043
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

EXOSC10 NCKAP1 PFAS PFKP URB1 NF1 SBF1 PHF3 SYNE2 EIF5B MACF1 HERC2 DYNC1H1

2.16e-056531701322586326
Pubmed

Effects of Genetic Polymorphism in CYP3A4 and CYP3A5 Genes on Tacrolimus Dose Among Kidney Transplant Recipients.

CYP3A4 CYP3A5

2.38e-052170227225724
Pubmed

Loss of cerebellar glutamate transporters EAAT4 and GLAST differentially affects the spontaneous firing pattern and survival of Purkinje cells.

SLC1A3 SLC1A6

2.38e-052170229741614
Pubmed

The combination of CYP3A4*22 and CYP3A5*3 single-nucleotide polymorphisms determines tacrolimus dose requirement after kidney transplantation.

CYP3A4 CYP3A5

2.38e-052170228704257
Pubmed

Genotype-phenotype associations of cytochrome P450 3A4 and 3A5 polymorphism with midazolam clearance in vivo.

CYP3A4 CYP3A5

2.38e-052170215900284
Pubmed

Genetic association in CYP3A4 and CYP3A5 genes elevate the risk of prostate cancer.

CYP3A4 CYP3A5

2.38e-052170236688864
Pubmed

Whole genome sequencing followed by functional analysis of genomic deletion encompassing ERCC8 and NDUFAF2 genes in a non-consanguineous Indian family reveals dysfunctional mitochondrial bioenergetics leading to infant mortality.

NDUFAF2 ERCC8

2.38e-052170238237647
Pubmed

The frameshift polymorphism CYP3A43_74_delA is associated with poor differentiation of breast tumors.

CYP3A4 CYP3A43

2.38e-052170220715157
Pubmed

Relative impact of CYP3A genotype and concomitant medication on the severity of atorvastatin-induced muscle damage.

CYP3A4 CYP3A5

2.38e-052170215900215
Pubmed

Cytochrome P450 3A4, 3A5, and 2C8 expression in breast, prostate, lung, endometrial, and ovarian tumors: relevance for resistance to taxanes.

CYP3A4 CYP3A5

2.38e-052170231309254
Pubmed

Impact of CYP3A5 and CYP3A4 gene polymorphisms on dose requirement of calcineurin inhibitors, cyclosporine and tacrolimus, in renal allograft recipients of North India.

CYP3A4 CYP3A5

2.38e-052170219343327
Pubmed

CYP3A4 and CYP3A5 polymorphisms and blood pressure response to amlodipine among African-American men and women with early hypertensive renal disease.

CYP3A4 CYP3A5

2.38e-052170219907160
Pubmed

CYP3A4*1G and CYP3A5*3 genetic polymorphisms alter the antihypertensive efficacy of amlodipine in patients with hypertension following renal transplantation
.

CYP3A4 CYP3A5

2.38e-052170227841150
Pubmed

Neurofibromin interacts with the cytoplasmic Dynein Heavy Chain 1 in melanosomes of human melanocytes.

NF1 DYNC1H1

2.38e-052170223583712
Pubmed

Precision Dosing for Tacrolimus Using Genotypes and Clinical Factors in Kidney Transplant Recipients of European Ancestry.

CYP3A4 CYP3A5

2.38e-052170233512723
InteractionCTAGE1 interactions

MIA3 CTAGE6 CTAGE8 CTAGE15 CTAGE4

8.70e-09101665int:CTAGE1
InteractionSNAPIN interactions

KRT26 KRT16 LAMA2 DYSF RGS7 MACF1 EXOC1 HERC2 DYNC1H1

1.14e-051691669int:SNAPIN
Cytoband7q21.1

CYP3A4 CYP3A5 CYP3A43

2.76e-06817037q21.1
Cytoband7q35

CTAGE6 CTAGE8 CTAGE15 CTAGE4

5.34e-055517047q35
CytobandEnsembl 112 genes in cytogenetic band chr7q35

CTAGE6 CTAGE8 CTAGE15 CTAGE4

1.09e-04661704chr7q35
GeneFamilyCTAGE family

CTAGE9 CTAGE6 CTAGE8 CTAGE15 CTAGE4

4.31e-08151265907
GeneFamilyCytochrome P450 family 3

CYP3A4 CYP3A5 CYP3A43

1.80e-05812631002
GeneFamilyWD repeat domain containing

WDR4 EML4 EML6 WSB2 WDFY4 ERCC8 MAPKBP1 CDC20 DYNC1I1

9.25e-052621269362
GeneFamilyRegulators of G-protein signaling

RGS7 RGS12 RGS8

4.01e-04211263720
GeneFamilyIntermediate filaments Type IV

SYNM NEFH

7.10e-0461262611
GeneFamilyEF-hand domain containing|Spectrins

SPTBN4 SPTBN5

9.89e-04712621113
GeneFamilyExocyst complex

EXOC8 EXOC1

1.68e-03912621055
GeneFamilyPaired boxes

PAX1 PAX6

1.68e-0391262675
GeneFamilyLaminin subunits

LAMA2 LAMB2

3.04e-03121262626
GeneFamilyDyneins, cytoplasmic

DYNC1H1 DYNC1I1

3.57e-03131262538
GeneFamilyLow density lipoprotein receptors

LRP4 LRP6

3.57e-03131262634
GeneFamilyPDZ domain containing

RGS12 LMO7 ARHGAP21 SNTA1 CARD14

4.25e-0315212651220
GeneFamilyDyneins, axonemal

DNAH1 DNAH17

6.12e-03171262536
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Granulocytic|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PFAS NYX EXOC8 SPTBN4 USHBP1 DNAH17 LRP4 SARDH

1.51e-07155170851f6447945389649d99dcf7603b396195c631ead
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Granulocytic-Mast_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PFAS NYX EXOC8 SPTBN4 USHBP1 DNAH17 LRP4 SARDH

1.51e-07155170823dc71cab28094ca0ac4d2baf4e24871ed107781
ToppCellfacs-Brain_Myeloid-Striatum|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLN8 KRT16 SLC1A3 KLHL9 MACF1 EDEM1 ZSWIM4

5.43e-061771707efb1990fd1d216f64261e81017299783afb24a1e
ToppCellCOVID-19-Heart-CM_+_EC_+_Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

PDE1C LAMA2 SLC1A3 RYR2 SLC5A1 FRY DYNC1I1

6.28e-061811707719eb532453ab7cd7893726885bc75d74a10b21e
ToppCell343B-Epithelial_cells-Epithelial-I_(AT1)|343B / Donor, Lineage, Cell class and subclass (all cells)

GPC1 WFS1 GPRC5A SLC5A1 MMP24 LMO7 FRMD3

7.00e-061841707cb15d6bae52c5ec251c2235859dc7e65f630ae23
ToppCell343B-Epithelial_cells-Epithelial-I_(AT1)-|343B / Donor, Lineage, Cell class and subclass (all cells)

GPC1 WFS1 GPRC5A SLC5A1 MMP24 LMO7 FRMD3

7.00e-061841707bde4eaabd3e9bdaed23867d23a919b9d84b52d4b
ToppCellRV-04._Ventricular_Cardiomyocyte_I|RV / Chamber and Cluster_Paper

PDE1C GCNT2 RYR2 SLC5A1 FRY LMO7 DYNC1I1

8.33e-0618917079c1debd65c13d63fd4f3158917d621b44b714c26
ToppCellLV-06._Ventricular_Cardiomyocyte_II|World / Chamber and Cluster_Paper

PDE1C LAMA2 GCNT2 SLC1A3 RYR2 SLC5A1 LMO7

8.63e-061901707de5ef606a002f85c2e0e3a36c1f259d0b85a76ff
ToppCellCOVID-19-Heart|COVID-19 / Disease (COVID-19 only), tissue and cell type

PDE1C SYNM LAMA2 RYR2 FRY DLC1 DYNC1I1

8.63e-061901707918ad5037881212008f9f69d5df5da91fd01422c
ToppCelldroplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IQSEC3 NPPC IFI44 GPRC5A MMP24 LRP2BP

9.02e-0612617064eeea015efe17e0aae5bd76b71fa70b5149dfada
ToppCellCOPD-Multiplet-Multiplet|COPD / Disease state, Lineage and Cell class

DCDC1 NCKAP1 GPRC5A LMO7 SYNE2 MACF1 BBOF1

1.06e-051961707af4cdc61830685a888a1209826c23bcf54a43084
ToppCellCOPD-Multiplet|COPD / Disease state, Lineage and Cell class

DCDC1 NCKAP1 GPRC5A LMO7 SYNE2 MACF1 BBOF1

1.06e-0519617076d02d494196e3f857d53eea46d9419690d43beca
ToppCellControl-Control-Lymphocyte-T/NK-CD4+_T_activated|Control / Disease, condition lineage and cell class

CERKL TRABD2A ZNF175 IFI44 MMP24 SYNE2 MACF1

1.13e-051981707ee71543559836fd59adc0da877b2ca538cba60cb
ToppCelldroplet-Fat-Gat-18m-Mesenchymal-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WWOX LONRF1 GPT DNAJC27 ABRAXAS1 ZFYVE26

1.18e-0513217064152529611eeacf0c547e2a134d5b98c45426b13
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Stem_cells-stem_cells_1|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

AMH NPPC MAP10 TUBGCP6 EDEM1 CRB2

2.62e-051521706375c9ef88c7703a002e868645a722c35e046ef1e
ToppCellLPS-antiTNF-Stromal_mesenchymal-Myocytic-Pericyte_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADAMTS19 TRABD2A LAMA2 NR2F1 RYR2 LRP6

3.14e-051571706bfec34182f052cf1c0d847ba53ea335d4d1190de
ToppCelldroplet-Fat-Scat-18m-Mesenchymal-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CERKL SLC1A3 RGS7 CLCN5 ANKEF1 CARD14

3.87e-0516317061eec7f5e5fed05fa21d3f81db588f10605f08ea7
ToppCellcontrol-Epithelial-Ionocyte|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

PDE1C CYP3A4 MFSD6L WDFY4 TGFB3 USHBP1

4.15e-0516517065cfba9a46bd8ceeca74a6493057b4d38af6b06fe
ToppCellNS-control-d_0-4-Epithelial-Ionocyte|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PDE1C CYP3A4 MFSD6L WDFY4 TGFB3 USHBP1

4.29e-0516617066d9fb239f69ba519844f593c00d515e1aac4ff50
ToppCellcontrol-Epithelial-Ionocyte|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

PDE1C CYP3A4 MFSD6L WDFY4 TGFB3 USHBP1

4.58e-051681706327b02f19f4a8607c033203824fdc60a1254331f
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-mesothelial_cell|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GALR3 GPT SLC1A3 ASTN1 CARD14 CRB2

4.74e-0516917060cece9b2bb1f58e465c20ec8735a4fc3c1021f03
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-mesothelial_cell-Mesothelium|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GALR3 GPT SLC1A3 ASTN1 CARD14 CRB2

4.74e-0516917066937c46b119d4ce382fc8c2fa5925ede5ae89c81
ToppCellCOVID-19-Heart-CM_+_Macrophage|COVID-19 / Disease (COVID-19 only), tissue and cell type

PDE1C LAMA2 SLC1A3 RYR2 FRY DYNC1I1

4.90e-0517017063f15242a1d3e4e9871d9170b2ef05842fb609c29
ToppCell356C-Lymphocytic-ILC-ILC-2|ILC / Donor, Lineage, Cell class and subclass (all cells)

SPTBN5 URB1 RIMKLB DNAH17 MIOS ZNF333

5.23e-0517217064977e1f4deae781750e27a8054deccd336cfb74a
ToppCellAT1-AT2_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

AADAC PDE1C WFS1 LAMB2 NR2F1 MMP24

5.23e-0517217060be41df5d35d818deb7316ac21c9366eb4b7bfd1
ToppCelldroplet-Kidney-nan-3m-Epithelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT16 NR2F1 HHIPL1 DYNC1I1 CRB2 FRMD3

5.23e-051721706073a503dc922e3e3ac3528e249b0f8b74402110b
ToppCellBAL-Mild-Epithelial-Epithelial-AT1/AT2|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PDE1C CYP3A4 MFSD6L RGS7 USHBP1 ASTN1

5.57e-051741706b7f5492ce8098f7eb0aef30ee558d00738d59d0e
ToppCellBAL-Mild-Epithelial-Epithelial-AT1/AT2-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

PDE1C CYP3A4 MFSD6L RGS7 USHBP1 ASTN1

5.57e-05174170671730503be3d9c839c4c9e950145e2101d682a1c
ToppCellBAL-Mild-Epithelial-Epithelial-AT1/AT2|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

PDE1C CYP3A4 MFSD6L RGS7 USHBP1 ASTN1

5.57e-051741706ee8ac51fa0b426ad7b7453371bb79c8bf8c1d358
ToppCellBAL-Mild-Epithelial-Epithelial-AT1/AT2-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PDE1C CYP3A4 MFSD6L RGS7 USHBP1 ASTN1

5.57e-051741706cafe4d6b5f08d8888e9db6e196c66df991c03e7b
ToppCelldroplet-Marrow-BM-1m-Lymphocytic-plasma_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLD3 DYSF SLC1A3 MMP24 MERTK SNTA1

6.13e-05177170626bad614560609d318bfc9c235a698bca4e1c22c
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_B-plasmablast-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

WWOX WFS1 PIWIL1 EML6 ABLIM3 CDC20

6.52e-051791706021d782134126c6f7dce6b6ea50cc54bdaa39987
ToppCelldroplet-Fat-Gat-18m-Endothelial-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DYSF MAP10 ABLIM3 TUBGCP6 BMP6 USHBP1

6.52e-05179170608cf9986804a6417a9afb19b50c69a3554f71ec6
ToppCellNS-moderate-d_16-33-Epithelial-Ionocyte|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

NPPC PDE1C CYP3A4 LAMB2 MFSD6L USHBP1

6.72e-0518017068af8b4af2dc72223ac71fc027e0d4280c5dd81f8
ToppCellMatrixFB-Fibroblast-A|MatrixFB / shred on cell class and cell subclass (v4)

SYNM EML4 ABLIM3 SLC1A3 DLC1 MACF1

6.72e-051801706adc64ad6033af705dd7b9163a83e20ef5c59f6eb
ToppCell5'-Adult-Appendix-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

WFS1 LAMB2 DYSF NR2F1 TGFB3 DLC1

7.15e-051821706fd786c88826ad3d5cc5c3d80f8e392d6be1b5267
ToppCellGlobus_pallidus-Neuronal-Inhibitory|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

IQSEC3 DNAJC27 ABLIM3 SLC1A6 NEFH ABCC8

7.15e-05182170604ccfa951eaa31fed6d140edb6c702d49363c5fa
ToppCellCOPD-Epithelial-Basal|COPD / Disease state, Lineage and Cell class

NPPC KRT16 NCKAP1 GPRC5A LMO7 ADGRA3

7.37e-0518317060f760e393edc91009bf6c7e02eeac039a1dfb4ed
ToppCellfacs-Liver-Non-hepatocytes-24m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NPPC LAMA2 GPRC5A RIMKLB DLC1 CRB2

7.37e-051831706ebe369dc80c4fbf8f4dbe947147f8c47507ffb60
ToppCell3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte-Ionocyte_L.0.7.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PDE1C CYP3A4 MFSD6L PFKP RGS7 SYNE2

7.59e-051841706a60802e11dcc5f932811260b08a95a32f60f6b19
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADAMTS19 TRABD2A LAMA2 NR2F1 RYR2 LRP6

7.59e-051841706689a8af81a79a4bb3123cfa01958c953eab5de98
ToppCell3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-ionocyte|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PDE1C CYP3A4 MFSD6L PFKP RGS7 SYNE2

7.59e-05184170639c230d32e4259bc784e0edfd9e2884c96898564
ToppCell3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PDE1C CYP3A4 MFSD6L PFKP RGS7 SYNE2

7.59e-0518417062a2fb691cc9414ef5b06c26239d2da03d6d7e5c2
ToppCell5'-Adult-Appendix-Endothelial-lymphatic_endothelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

WFS1 LAMB2 DYSF NR2F1 TGFB3 DLC1

7.59e-051841706453295362888c9a59d0e73c7a5b15914c50ff591
ToppCellCOVID-19-Heart-CM_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

PDE1C LAMA2 SLC1A3 RYR2 FRY DYNC1I1

7.82e-051851706549eeb521c3985bff396ea0f202db21822efa51f
ToppCellLV-15._Ventricular_Cardiomyocyte_III|World / Chamber and Cluster_Paper

GCNT2 SLC1A3 RYR2 SLC5A1 FRY LMO7

7.82e-0518517066baccb26f999145e51b91d94315bf8d4655bef31
ToppCell3'-Child04-06-SmallIntestine-Endothelial-lymphatic_endothelial|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IQSEC3 SYNM WFS1 ABLIM3 NR2F1 USHBP1

8.06e-051861706eeacf59a9e6bf1c9fd59b6b13d35e8abae228cf0
ToppCellmoderate-Epithelial-Ionocyte|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

NPPC PDE1C CYP3A4 LAMB2 MFSD6L USHBP1

8.30e-0518717063e3fe2d5712a0ac477cddefe56705d4b8d8f7eac
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Degenerative_Podocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS19 GPRC5A FRY DYNC1I1 CRB2 FRMD3

8.54e-0518817069db778c1d9e622a68337212296e3a1ed8f771fa5
ToppCell367C-Lymphocytic-CD4_T-cell-Proliferating_T_cell|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

NPPC TPGS2 PTH2R GINS2 CDC20 SMC1B

8.54e-051881706f5102e8d95506c25c675094b86162a6a50087b64
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RYR2 FRY DLC1 ABCC8 ASTN1 DYNC1I1

8.80e-0518917067fbe855bfdb47d35e040b04a80fe4b729a3764e8
ToppCelldroplet-Kidney-nan-3m-Epithelial-Stroma____kidney_mesangial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYNM NR2F1 TGFB3 ABCC8 FGF4 HCRTR1

8.80e-051891706a959c9d6a0866582688a4204d625c1e5a123e93d
ToppCellfacs-Lung-nan-3m-Endothelial-Capillary_Aerocyte_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCKAP1 GPRC5A RGS12 FRY LMO7 MERTK

8.80e-05189170609dd2b3d89416192e84abe302a6237b8f3fdcb6e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RYR2 FRY DLC1 ABCC8 ASTN1 DYNC1I1

8.80e-05189170606b35abecd29f902cf251fcc1f6ad33db7ab08a2
ToppCellmoderate-Epithelial-Ionocyte|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

NPPC PDE1C CYP3A4 LAMB2 MFSD6L USHBP1

8.80e-0518917066011b747e27d61d222380a7bffdd921a68e9b657
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LAMB2 ZHX2 SLC1A3 LRP4 PAX6 MERTK

9.06e-0519017065c64b727669b23d2a23c8ad1d5d6caab7af37d56
ToppCellLV-06._Ventricular_Cardiomyocyte_II|LV / Chamber and Cluster_Paper

PDE1C LAMA2 GCNT2 SLC1A3 RYR2 LMO7

9.32e-05191170625f3eb34f4e70761e81e84c8a5829f216108cbc6
ToppCellfacs-Lung-Endomucin_-18m-Endothelial-Capillary_Aerocyte_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPRC5A RGS12 FRY LMO7 LRP4 MERTK

9.32e-051911706df8cdbc26443e55a203cbafa21b0952a2a55b9bf
ToppCell3'-Pediatric_IBD-SmallIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IQSEC3 SYNM WFS1 DYSF NR2F1 USHBP1

9.32e-051911706361b123c8289015206d5e706ab2c615d9a724179
ToppCellCOPD-Epithelial-Club|COPD / Disease state, Lineage and Cell class

AADAC NCKAP1 GCNT2 GPRC5A LMO7 ADGRA3

9.32e-051911706c909cf5fa0e6519aa93a47d2c3fcd2ae2163cd8d
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

EML4 ABLIM3 SLC1A3 NR2F1 RYR2 ADGRA3

9.32e-05191170608720998aa55131d7377c4c67c4c935865bd7d79
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_GGH|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NPPC PRLHR GCNT2 RGS12 PTH2R RGS8

9.32e-05191170606760c3bb40e4f66879a5f5e09c9abfce4ebbba3
ToppCell10x_5'_v1-Non-neoplastic-Lymphoid-NK|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

WDR4 IFI44 TUBGCP6 GINS2 MACF1 SNTA1

9.59e-051921706930319cbd82b9e54864147ffcdc8bd0ea7b937be
ToppCellLV-04._Ventricular_Cardiomyocyte_I|LV / Chamber and Cluster_Paper

GCNT2 SLC1A3 RYR2 FRY LMO7 DYNC1I1

9.59e-051921706ad19e2c1d36a0566c9b12ced10db78f4781c8ea6
ToppCell10x_5'_v1-Non-neoplastic-Lymphoid-NK-NK|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

WDR4 IFI44 TUBGCP6 GINS2 MACF1 SNTA1

9.59e-051921706c7bcebcb88a25b2c97d798120efa9d5958e7f798
ToppCell3'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SYNM WFS1 DYSF ABLIM3 NR2F1 TGFB3

9.59e-051921706ee9a23a4f00424a50bd7907cf3b12dc50027877e
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-AC-like-AC-like_Prolif-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CYP3A4 RGS7 ABCC8 CCDC87 ADGRA3 LRP2BP

9.59e-051921706d6f656be2698bd215717d35f4e7ab727c08c61e0
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

LAMA2 ABLIM3 NR2F1 RYR2 DLC1 MACF1

9.87e-05193170699525545552b371c86b18b6ea6f4897dc6e9a9ec
ToppCell5'-Adult-SmallIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IQSEC3 SYNM WFS1 DYSF ABLIM3 NR2F1

9.87e-051931706bd0027fa97de41ae22ff64a61c8e217496f122ca
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

LAMA2 ABLIM3 SLC1A3 NR2F1 RYR2 DYNC1I1

1.02e-041941706011e14d9ed1393275f892060e7708ffadcd0767f
ToppCell10x_5'_v1-Non-neoplastic-Lymphoid-NK-NK-Z|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

WDR4 SYNM EML4 IFI44 TUBGCP6 MACF1

1.02e-0419417063211d89440a6f4a9b3d4cfb755890816944242ec
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DCDC1 GPRC5A PFKP LMO7 SYNE2 ADGRA3

1.02e-041941706e577d9e88390b36b5a09b97fe1026089892275a3
ToppCellCOVID-19-Heart-CM_1|Heart / Disease (COVID-19 only), tissue and cell type

PDE1C GCNT2 SLC1A3 RYR2 LMO7 DYNC1I1

1.04e-041951706f1ef50331eda8f1239dba6ea970df4eaccf032f1
ToppCell10x5'v1-week_17-19-Endothelial-stroma-sinusoidal_EC|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

IQSEC3 NCKAP1 GPRC5A NR2F1 BMP6 USHBP1

1.04e-04195170622a481927147ec4ae9d59e6af7c87df0e9cb51e4
ToppCellCOVID-19-lung-Macrophage_CD163hi_MERTKhi|lung / Disease (COVID-19 only), tissue and cell type

MYO9B DYSF WDFY4 SLC1A3 TBC1D14 MERTK

1.04e-041951706148fff8c3c9ba45ec36e98dff1be57e3f8294506
ToppCellCOVID-19-Heart-CM_2|Heart / Disease (COVID-19 only), tissue and cell type

PDE1C LAMA2 SLC1A3 RYR2 FRY LMO7

1.04e-04195170675fc81bddb246dca3b437fb60827b1d4fe416405
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

WWOX GCNT2 PTH2R CLCN5 LMO7 ADGRA3

1.04e-0419517066477e6e7be5bd8eb99119a12ae16334ccddecd43
ToppCellMid-temporal_gyrus_(MTG)-Neuronal|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

EML6 RGS7 RYR2 SPTBN4 FRY DYNC1I1

1.07e-041961706676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_neuro-secretory-Ionocyte_n_Brush|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CLN8 PDE1C PRR36 MFSD6L RGS7 KCNU1

1.07e-041961706ef650ff106a76c1e926e13c7f002fbc452cc48ae
ToppCellCOVID-19-Myeloid-Transitioning_MDM|COVID-19 / group, cell type (main and fine annotations)

MYO9B DYSF SLC1A3 TBC1D14 MERTK DHX34

1.07e-0419617064929cfed1f150c1fde4d79cb49895c2ea467a18f
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

WFS1 LAMB2 GPRC5A MMP24 DLC1 LMO7

1.07e-041961706eb68f7954e7c2f86d05e740e95b6e74805a6053f
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

LAMA2 SLC1A3 NR2F1 DLC1 MACF1 DYNC1I1

1.07e-0419617061450cb69c5bf469e97c03bf1890f6f7c54165b8a
ToppCell10x5'-bone_marrow-Hematopoietic_Erythro-Mega|bone_marrow / Manually curated celltypes from each tissue

GPT TPGS2 PTH2R APOL4 GINS2 CDC20

1.07e-041961706707eecbb2b14051fd843afa66035014ec59e6bd5
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_neuro-secretory|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CLN8 PDE1C PRR36 MFSD6L RGS7 KCNU1

1.07e-04196170672b6a68ee760599ea86cd2d712bfd17b7b4ee417
ToppCell10x5'-bone_marrow-Hematopoietic_Erythro-Mega-Erythrocytic_early|bone_marrow / Manually curated celltypes from each tissue

GPT TPGS2 PTH2R APOL4 GINS2 CDC20

1.07e-041961706507254c4c00e535fe01851431b5b74a5f15d9592
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Macroglial-astrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO9B SLC1A3 EXOC1 CRB2 BBOF1

1.09e-041231705a45d6907c041ad3f3218cd46dccfc25d4bd961cb
ToppCellBronchial-10x5prime-Epithelial-Epi_airway_neuro-secretory-Neuroendocrine|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PLA2G4D RGS7 RYR2 SPTBN4 GINS2 ASTN1

1.10e-0419717063a0e97bfebe82f9687d518baaad7f20d0ffea8a1
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

LAMA2 SLC1A3 NR2F1 DLC1 MACF1 DYNC1I1

1.10e-0419717060034bae02ee7fcfea520d453ca3c842ab6963b12
ToppCellprimary_auditory_cortex_(A1C)-Neuronal|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

EML6 RGS7 RYR2 SPTBN4 FRY DYNC1I1

1.14e-0419817066d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

EML6 RGS7 RYR2 SPTBN4 FRY DYNC1I1

1.14e-0419817068ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

LAMA2 SLC1A3 NR2F1 DLC1 MACF1 DYNC1I1

1.14e-04198170617dc055e2a289496d9c5cdbf3297bdf906dc6d22
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

EML6 RGS7 RYR2 SPTBN4 FRY DYNC1I1

1.14e-0419817064ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCellParenchyma_COVID-19-Immune-TX-MoAM-4|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

TPGS2 GCNT2 PLD3 PFKP SLC1A3 NDUFS8

1.14e-041981706a7eed9eeb728a8796e2780090cc244856efd8c65
ToppCellmild-CD4+_Tcm|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TRABD2A EML4 IFI44 PHF3 SYNE2 MACF1

1.17e-04199170606c8a0e39f7a33736548f04a5e2263334c8541cf
ToppCelldroplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IQSEC3 IFI44 GPRC5A MMP24 LRP2BP

1.18e-04125170535042ed43045dddc341b76cc5f9fe31b5ba0abb8
ToppCellLPS_IL1RA-Endothelial-Endothelial|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

NCKAP1 DLC1 USHBP1 SYNE2 MACF1 DYNC1H1

1.20e-04200170672ea9882a8ed26fa1534aeb6ba0d1897dccc20c5
ToppCellHematolymphoid-Endothelial-NOSTRIN|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

LAMA2 ABLIM3 BMP6 FRY DLC1 SYNE2

1.20e-042001706032df80aa5c40991e1c1e80f9d8da106e6aeaee2
ToppCellMacroglial-Astrocytes|Macroglial / cells hierarchy compared to all cells using T-Statistic

PFKP SLC1A3 PAX6 MERTK SNTA1 ADGRA3

1.20e-042001706941536b7c32f1e63c70535233b2ccce0cd7bf96e
ToppCellBiopsy_Other_PF-Epithelial-KRT5-/KRT17+|Biopsy_Other_PF / Sample group, Lineage and Cell type

GPC1 CDC42BPG KRT16 GPRC5A MMP24 LMO7

1.20e-042001706077e6b9340686de9d0f11b035a8954e1f6a1b790
ToppCellLPS_IL1RA-Endothelial|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

NCKAP1 DLC1 USHBP1 SYNE2 MACF1 DYNC1H1

1.20e-0420017065c092b2ecc081b5d04476c56333c338cd89ab984
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

EML4 PHF3 SYNE2 MACF1 DYNC1H1

6.80e-0549955GAVISH_3CA_METAPROGRAM_CD8_T_CELLS_CHROMATIN
DrugAC1L1J6H

CYP3A4 CYP3A5 CYP3A43 GPT IFI44 USHBP1 ABCC8 LRP4 LRP6 HTR3B LRP2BP

1.52e-0623616811CID000004889
Drug(+/-)-thalidomide; Down 200; 100uM; MCF7; HG-U133A

GPC1 DTX3 ANKRD26 RGS12 ERCC8 POGLUT1 PHF3 EIF5B DHX34

1.45e-051941689606_DN
Drug15(S)-15-methyl Prostaglandin E2; Up 200; 10uM; PC3; HT_HG-U133A

AADAC GCNT2 GPRC5A TBC1D8B TAF6L NF1 SBF1 DNAH17 ARAP1

1.45e-0519416897494_UP
DrugHydrastinine hydrochloride [4884-68-8]; Down 200; 16.4uM; MCF7; HT_HG-U133A

CYP3A4 GCNT2 PLD3 RYR2 NF1 PHF3 LRP6 MERTK SNTA1

1.51e-0519516892283_DN
DrugTiclopidine hydrochloride [53885-35-1]; Down 200; 13.4uM; MCF7; HT_HG-U133A

WDR4 PRR36 MYO9B GCNT2 NR2F1 RGS12 NF1 DHX34 CARD14

1.51e-0519516894155_DN
Drugacetylmethadol

CYP3A4 CYP3A5 GPT LAMA2

1.55e-05211684CID000010517
DrugKaempferol [520-18-3]; Up 200; 14uM; MCF7; HT_HG-U133A

WWOX CYP3A5 PLD3 RGS12 SPTBN5 URB1 NF1 MIOS ZFYVE26

1.57e-0519616893579_UP
DrugProguanil hydrochloride [637-32-1]; Up 200; 13.8uM; MCF7; HT_HG-U133A

GALR3 CYP3A4 NYX RGS12 BMP6 NF1 LRP6 MACF1 ARAP1

1.64e-0519716895506_UP
DrugN-Acetyl-DL-homocysteine Thiolactone [1195-16-0]; Down 200; 25.2uM; MCF7; HT_HG-U133A

PDE1C CYP3A4 MYO9B NR2F1 RYR2 TAF6L DNAH17 DHX34 ARAP1

1.64e-0519716893930_DN
DrugTenoxicam [59804-37-4]; Up 200; 11.8uM; MCF7; HT_HG-U133A

AMH MYO9B LAMA2 GCNT2 DYSF NR2F1 SLC5A1 PHF3 SNTA1

1.64e-0519716892860_UP
DrugTrimeprazine tartrate [4330-99-8]; Down 200; 5.4uM; MCF7; HT_HG-U133A

WDR4 MYO9B ANKRD26 PLD3 NR2F1 CLCN5 SBF1 MACF1 MAPKBP1

1.70e-0519816897235_DN
Drug(S)-(-)-Atenolol [93379-54-5]; Down 200; 15uM; MCF7; HT_HG-U133A

CLN8 WDR4 MYO9B NR2F1 RYR2 PHF3 DNAH17 DHX34 ARAP1

1.70e-0519816896444_DN
Drugpolybrominated biphenyl

CYP3A4 CYP3A5 CYP3A43 GPT MERTK

1.77e-05441685CID000042948
DrugPF-00562151-00 [351320-12-2]; Down 200; 10uM; MCF7; HT_HG-U133A

AMH CYP3A4 MYO9B NR2F1 TAF6L BMP6 DNAH17 DHX34 SNTA1

1.77e-0519916895954_DN
DrugTrichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A

AMH GALR3 NR2F1 RGS12 SPTBN5 DLC1 ABCC8 HTR3B CARD14

1.77e-0519916893872_UP
Drugprecocene I

CYP3A4 CYP3A5 GPT

2.15e-0581683CID000028619
Drugplakin

KRT16 SPTBN4 SPTBN5 SYNE2 MACF1 DYNC1H1

3.25e-05821686CID000018752
Drugsimvastatin

CYP3A4 CYP3A5 CYP3A43 GPT IFI44 USHBP1 ABCC8 LRP4 LRP6 FGF4 HTR3B LRP2BP

3.46e-0539016812CID000054454
DrugNDMA

WWOX CYP3A4 SYNM CYP3A5 GPT

4.05e-05521685CID000008749
Drug4-hydroxymidazolam

CYP3A4 CYP3A5

5.41e-0521682ctd:C042940
Drugdehydrorotenone

WWOX CYP3A5

5.41e-0521682CID000099190
Drugnorverapamil

CYP3A4 CYP3A5

5.41e-0521682ctd:C016904
Drug5,6-dihydro-2H-pyran-2-one

CYP3A4 CYP3A5

5.41e-0521682CID000520660
DrugNSC254180

SYNM CYP3A5

5.41e-0521682CID000099639
Drugnotopterol

CYP3A4 CYP3A5

5.41e-0521682CID005320227
DrugN-acetyl-S--(1,2,3,4,4-pentachlorobutadienyl)cysteine sulfoxide

CYP3A4 CYP3A5

5.41e-0521682ctd:C114289
Drugacetylalanylalanine

SYNM CYP3A5

5.41e-0521682CID000088328
Drug3-hydroxyxanthine

WWOX SYNM

5.41e-0521682CID000083520
Drug6 beta-hydroxytestosterone

CYP3A4 CYP3A5

5.41e-0521682ctd:C025591
Drug2-acetamidonaphthalene

AADAC CYP3A5

5.41e-0521682CID000011394
DrugCQA 206-291

CYP3A4 CYP3A5

5.41e-0521682ctd:C059483
Drugfructus schizandrae, radix ginseng, radix ophiopogonis drug combination

CYP3A4 CYP3A5

5.41e-0521682ctd:C009252
DrugAC1L1IZE

RYR2 DNAH1 P2RX6 DNAH17 EIF5B NME3 DYNC1H1

5.44e-051311687CID000004799
Drugsphondin

CYP3A4 CYP3A5 IFI44

6.23e-05111683CID000108104
DrugAC1Q6DJO

WWOX MYO9B GPT LAMA2 RFX5 GINS2

6.62e-05931686CID000000630
DrugAC1L1CIR

NPPC EXOSC10 TGFB3 MERTK CARD14

6.88e-05581685CID000001918
Drugnitroxyl

GPC1 WWOX CYP3A5 RYR2 NEFH NF1 PAX6 CARD14

7.18e-051851688CID000000945
Drug5-hydroxydiclofenac

WWOX CYP3A4 CYP3A5

8.27e-05121683CID003052566
DrugFurosemide [54-31-9]; Down 200; 12uM; MCF7; HT_HG-U133A

DYSF ERCC8 NF1 CLCN5 SLC2A6 DNAH17 DHX34 ARAP1

9.65e-0519316883197_DN
Drugvanadyl

NPPC PDE1C IFI44 LAMB2 ZHX2 DNAH1 DNAH17 PRKAR1A LRP6 DYNC1H1

9.89e-0530716810CID000061671
DrugTetrahydroxy-1,4-quinone monohydrate [319-89-1]; Down 200; 21uM; MCF7; HT_HG-U133A

WWOX WDR4 PRR36 ANKRD26 NF1 DLC1 DHX34 TOP3B

1.00e-0419416884159_DN
DrugAconitine [302-27-2]; Up 200; 6.2uM; MCF7; HT_HG-U133A

PRR36 LAMA2 NR2F1 URB1 NF1 DLC1 TOP3B DYNC1I1

1.00e-0419416882776_UP
DrugPentamidine isethionate [140-64-7]; Up 200; 6.8uM; PC3; HT_HG-U133A

PRR36 CYP3A4 MYO9B IFI44 NF1 DNAH17 CCDC87 MIOS

1.00e-0419416884573_UP
Drug15d-PGJ2; Up 200; 10uM; PC3; HG-U133A

GPC1 NCKAP1 GALR3 NYX SLC1A3 DLC1 CLCN5 PAX1

1.00e-041941688446_UP
DrugDihydroergotoxine mesylate [8067-24-1]; Down 200; 6.4uM; MCF7; HT_HG-U133A

WDR4 PLD3 NR2F1 TAF6L ERCC8 NF1 DHX34 ARAP1

1.00e-0419416882793_DN
DrugFenbufen [36330-85-5]; Down 200; 15.8uM; MCF7; HT_HG-U133A

WDR4 NCKAP1 DYSF NR2F1 NF1 CLCN5 PHF3 BBOF1

1.04e-0419516882308_DN
DrugPargyline hydrochloride [306-07-0]; Down 200; 20.4uM; PC3; HT_HG-U133A

GCNT2 PLD3 KIAA0753 SBF1 LRP6 DHX34 ARAP1 BBOF1

1.04e-0419516882102_DN
DrugChlorpromazine hydrochloride [69-09-0]; Down 200; 11.2uM; MCF7; HT_HG-U133A

GPC1 PRR36 MYO9B PLD3 TGFB3 SBF1 LRP6 MAPKBP1

1.04e-0419516881700_DN
DrugEstradiol-17 beta [50-28-2]; Up 200; 14.6uM; PC3; HT_HG-U133A

AMH WWOX GALR3 RGS12 SPTBN5 NF1 SARDH TOP3B

1.04e-0419516886718_UP
Drug(R)-Propranolol hydrochloride [13071-11-9]; Down 200; 13.6uM; PC3; HT_HG-U133A

MYO9B IFI44 URB1 CLCN5 PHF3 ASCC2 DHX34 SNTA1

1.04e-0419516885814_DN
DrugTHDCA

CYP3A4 CYP3A5 GPT

1.07e-04131683CID000119046
DrugNSC-13158

WWOX CYP3A4 CYP3A5

1.07e-04131683CID000079470
Drug2-chloro-1,1-difluoroethene

CYP3A4 CYP3A5 GPT

1.07e-04131683CID000009664
DrugMeclofenamic acid sodium salt monohydrate [6385-02-0]; Down 200; 11.8uM; MCF7; HT_HG-U133A

PRR36 TAF6L NF1 SBF1 LRP6 MERTK TOP3B ARAP1

1.07e-0419616882291_DN
DrugEthambutol dihydrochloride [1070-11-7]; Down 200; 14.4uM; MCF7; HT_HG-U133A

GPC1 WWOX DYSF ABLIM3 RGS12 NF1 DHX34 SNTA1

1.07e-0419616884120_DN
DrugAmyleine hydrochloride [532-59-2]; Down 200; 14.8uM; PC3; HT_HG-U133A

WWOX IFI44 TBC1D8B TAF6L DLC1 LMO7 ASTN1 DHX34

1.11e-0419716884089_DN
DrugAlclometasone dipropionate [667634-13-2]; Down 200; 7.6uM; PC3; HT_HG-U133A

IFI44 ANKRD26 RGS7 TAF6L BMP6 NF1 SBF1 ARAP1

1.11e-0419716885752_DN
Drug(-)-Adenosine 3',5'-cyclic monophosphate [60-92-4]; Up 200; 12.2uM; MCF7; HT_HG-U133A

IFI44 LAMA2 RGS12 FRY NF1 DLC1 MIOS TOP3B

1.11e-0419716883531_UP
DrugPentolinium bitartrate [52-62-0]; Up 200; 7.4uM; MCF7; HT_HG-U133A

CYP3A4 CYP3A5 IFI44 RYR2 SPTBN4 SPTBN5 SBF1 DNAH17

1.11e-0419716882305_UP
DrugAmikacin hydrate [37517-28-5]; Up 200; 6.6uM; MCF7; HT_HG-U133A

MIA3 CYP3A4 CYP3A5 GCNT2 BMP6 SBF1 ASTN1 DHX34

1.11e-0419716883233_UP
Drugstaurosporine; Up 200; 1uM; MCF7; HG-U133A

AMH CYP3A4 DTX3 ABLIM3 SLC5A1 POGLUT1 ASCC2 PAX1

1.11e-041971688312_UP
DrugDiprophylline [479-18-5]; Down 200; 15.8uM; MCF7; HT_HG-U133A

CLN8 WDR4 MYO9B LAMB2 NF1 MACF1 ZFYVE26 MAPKBP1

1.11e-0419716885482_DN
DrugAlprostadil [745-65-3]; Down 200; 11.2uM; PC3; HT_HG-U133A

AMH WDR4 SLC1A6 RGS7 MMP24 DLC1 MERTK DHX34

1.15e-0419816884099_DN
DrugSulfachloropyridazine [80-32-0]; Down 200; 14uM; MCF7; HT_HG-U133A

MIA3 PRR36 GCNT2 NR2F1 RGS12 RYR2 TAF6L NF1

1.15e-0419816883944_DN
DrugTrimipramine maleate salt [521-78-8]; Up 200; 9.8uM; MCF7; HT_HG-U133A

CYP3A5 CYP3A43 LAMA2 RGS12 SPTBN5 NF1 DLC1 ZNF646

1.15e-0419816883342_UP
DrugAcacetin [480-44-4]; Up 200; 14uM; MCF7; HT_HG-U133A

CYP3A5 GCNT2 NR2F1 RGS12 RYR2 NEFH FRY MERTK

1.15e-0419816886044_UP
DrugLobelanidine hydrochloride [6112-86-3]; Up 200; 10.6uM; MCF7; HT_HG-U133A

GPC1 ZNF175 RGS7 LRP4 LRP6 SARDH HCRTR1 ARAP1

1.15e-0419816885500_UP
DrugCondelphine [7633-69-4]; Up 200; 8.8uM; PC3; HT_HG-U133A

WWOX DTX3 IFI44 TAF6L NF1 LMO7 DNAH17 DHX34

1.19e-0419916886357_UP
DrugFluvastatin sodium salt [93957-55-2]; Up 200; 9.2uM; HL60; HT_HG-U133A

GPC1 LAMA2 LAMB2 RGS12 SLC5A1 SPTBN5 ASTN1 MERTK

1.19e-0419916883032_UP
DrugGanciclovir [82410-32-0]; Up 200; 15.6uM; HL60; HT_HG-U133A

GPC1 CYP3A5 LAMB2 RGS12 SLC5A1 LRP6 ARAP1 ZNF646

1.23e-0420016883030_UP
DrugXylazine [7361-61-7]; Up 200; 18.2uM; MCF7; HT_HG-U133A

PDE1C PRR36 RGS12 FRY DNAH17 MIOS DHX34 ZNF646

1.23e-0420016882788_UP
Drug9-hydroxyellipticine

CYP3A4 CYP3A5 TOP3B

1.35e-04141683CID000091643
Drugtamarixetin

WWOX CYP3A4 CYP3A5

1.35e-04141683CID005281699
Drugg due

AADAC CYP3A4 CYP3A5 MOS

1.40e-04361684CID000062612
Drugerythralosamine

CYP3A4 CYP3A5

1.62e-0431682CID000352196
DrugRifabutin

AADAC CYP3A4

1.62e-0431682ctd:D017828
Drug3-methoxymorphinan

CYP3A4 CYP3A5

1.62e-0431682ctd:C028657
Drugdechloroethylcyclophosphamide

CYP3A4 CYP3A5

1.62e-0431682ctd:C064445
Drug6 beta-hydroxydexamethasone

CYP3A4 CYP3A5

1.62e-0431682CID000063050
Drugterritrem C

CYP3A4 CYP3A5

1.62e-0431682CID000160306
DrugN-hydroxy-L-tyrosine

WWOX CYP3A5

1.62e-0431682CID000174052
Drugtetrabenzonaphthalene

SYNM CYP3A5

1.62e-0431682CID000067449
Drug4,4'-dihydroxyantipyrine

CYP3A5 MOS

1.62e-0431682CID000126307
Drugmegazol

WWOX CYP3A5

1.62e-0431682CID000029698
Drug1-hydroxymethylmidazolam

CYP3A4 CYP3A5

1.62e-0431682ctd:C040081
Drugfomocaine

AADAC CYP3A5

1.62e-0431682CID000071693
Drugphenanthrene-4,5-dicarboxylic acid

WWOX CYP3A5

1.62e-0431682CID000095075
Drug3-sulfanylhexyl acetate

AMH SYNE2

1.62e-0431682CID000518810
DrugN-acetyl-S-pentachloro-1,3-butadienylcysteine

CYP3A4 CYP3A5

1.62e-0431682ctd:C049739
DrugC15503

WWOX CYP3A5

1.62e-0431682CID005461147
DrugSCE-129

WWOX NDUFAF2 SLC1A3 NDUFS8 MACF1 HTR3B HERC2

1.63e-041561687CID000002648
DrugPRODAN

AMH SPTBN4 SPTBN5

1.68e-04151683CID000028127
DrugUROX

WWOX CYP3A4 CYP3A5

1.68e-04151683CID000008799
DrugAC1L1AFQ

WWOX RIMKLB MERTK

1.68e-04151683CID000000969
Drug2-(allylthio)pyrazine

CYP3A4 CYP3A5 GPT

2.06e-04161683CID003025899
Drug2,2,2-trichloroethanol

CYP3A4 CYP3A5 CYP3A43 GPT SLC5A1

2.06e-04731685CID000008259
Drugdipyrone

NPPC CYP3A5 GPT RYR2

2.12e-04401684CID000003110
Drugsenecionine

CYP3A4 CYP3A5 CYP3A43 GPT GPRC5A

2.20e-04741685ctd:C009237
DrugPDEs

NPPC PDE1C EXOSC10 AKAP3 PRKAR1A CARD14

2.24e-041161686CID003036959
DrugEpi Lovastatin

CYP3A4 CYP3A5 CYP3A43 GPT TGFB3 NEFH USHBP1 LRP4 LRP6 LRP2BP

2.32e-0434116810CID000003962
DiseaseMalignant neoplasm of breast

GPC1 ADAMTS19 WWOX CYP3A4 DTX3 LAMA2 DYSF NR2F1 NLRP9 NF1 ABRAXAS1 ANKEF1 SYNE2 FGF4 MACF1 ZFYVE26 HERC2 ZNF646

1.93e-05107415818C0006142
Diseasemetabolonic lactone sulfate measurement

CYP3A4 CYP3A5 CYP3A43

1.37e-04191583EFO_0800659
Diseasetacrolimus measurement

CYP3A4 CYP3A5

1.70e-0441582EFO_0008458
Diseasemuscular dystrophy (implicated_via_orthology)

LAMA2 DYSF SNTA1

1.87e-04211583DOID:9884 (implicated_via_orthology)
Diseaseepilepsy (implicated_via_orthology)

WWOX SLC1A3 SLC1A6 KCNU1 SBF1 DYNC1H1

2.55e-041631586DOID:1826 (implicated_via_orthology)
Diseaseunipolar depression, neuroticism measurement

WWOX PHF3 ARHGAP21

2.81e-04241583EFO_0003761, EFO_0007660
DiseaseCongenital muscular dystrophy (disorder)

LAMA2 SYNE2

4.21e-0461582C0699743
Diseaseepisodic ataxia type 6 (implicated_via_orthology)

SLC1A3 SLC1A6

4.21e-0461582DOID:0050994 (implicated_via_orthology)
DiseaseX-12063 measurement

CYP3A4 CYP3A5 ANKRD26 BMP6 NF1 HCRTR1

5.14e-041861586EFO_0021283
DiseaseIntellectual Disability

IQSEC3 WDR4 RGS7 FRY NF1 MACF1 ASTN1 PAX6 DYNC1H1

7.14e-044471589C3714756
Diseaseglucagon-like peptide-1 measurement, glucose tolerance test

GPT SLC5A1

7.81e-0481582EFO_0004307, EFO_0008465
DiseaseProfound Mental Retardation

RGS7 FRY NF1 PAX6 DYNC1H1

9.33e-041391585C0020796
DiseaseMental Retardation, Psychosocial

RGS7 FRY NF1 PAX6 DYNC1H1

9.33e-041391585C0025363
DiseaseMental deficiency

RGS7 FRY NF1 PAX6 DYNC1H1

9.33e-041391585C0917816
DiseaseDuchenne muscular dystrophy (implicated_via_orthology)

EML4 KCNU1 SNTA1

9.45e-04361583DOID:11723 (implicated_via_orthology)
DiseaseDisorder of eye

CLN8 CERKL WFS1 NYX PAX6 MERTK

1.02e-032121586C0015397
Diseasesquamous cell lung carcinoma, family history of lung cancer

WWOX MFSD6L SLC1A6 NF1

1.14e-03851584EFO_0000708, EFO_0006953
DiseaseOdontome

LRP4 PAX6

1.25e-03101582C0524730
Diseasearrhythmogenic right ventricular cardiomyopathy (is_implicated_in)

RYR2 TGFB3

1.25e-03101582DOID:0050431 (is_implicated_in)
DiseaseTooth Abnormalities

LRP4 PAX6

1.25e-03101582C0040427
Diseasetestosterone measurement

MIA3 WWOX DCDC1 CYP3A4 MYO9B EML4 KIAA0753 SLC30A6 BMP6 URB1 NF1 SYNE2 MACF1 HHIPL1 ARHGAP21 ARAP1

1.40e-03127515816EFO_0004908
Diseasenevus count, cutaneous melanoma

MIA3 GPRC5A SYNE2 HERC2

1.47e-03911584EFO_0000389, EFO_0004632
Diseasemethionine sulfone measurement

CYP3A4 CYP3A43

1.82e-03121582EFO_0800072
Diseaseactinic keratosis

MMP24 HERC2

2.49e-03141582EFO_0002496
DiseaseSchizophrenia

CYP3A4 CYP3A5 MYO9B LAMA2 SLC1A3 SLC1A6 RGS12 APOL4 PAX6 HTR3B TOP3B HCRTR1

2.94e-0388315812C0036341
Diseasealcohol dependence measurement

ABCC8 ARHGAP21 ARAP1

3.22e-03551583EFO_0007835
Diseaseforced expiratory volume

CERKL WWOX CYP3A4 EML4 DNAJC27 ZHX2 ABLIM3 RYR2 KIAA0753 BMP6 ASCC2

3.60e-0378915811EFO_0004314
Diseasemuscular dystrophy (is_implicated_in)

LAMA2 DYSF

3.68e-03171582DOID:9884 (is_implicated_in)
Diseasecutaneous melanoma, hair color

LMO7 SYNE2 HERC2

4.52e-03621583EFO_0000389, EFO_0003924
Diseaseobsessive-compulsive disorder, autism spectrum disorder

PTH2R DLC1

4.59e-03191582EFO_0003756, EFO_0004242
Diseasereasoning

PDE1C WWOX

4.59e-03191582EFO_0004350

Protein segments in the cluster

PeptideGeneStartEntry
AWLRLALSSREDELV

USHBP1

181

Q8N6Y0
LDDRWQFKRSRLLDT

ABRAXAS1

351

Q6UWZ7
ERAWALDVAELHRAL

GPT

211

P24298
TISEFDRLALWKRNE

ABLIM3

661

O94929
AAADETLRLWRCFEL

CDC20

461

Q12834
WLAARTAERNLSDLR

CTAGE4

466

Q8IX94
WLAARTAERNLSDLR

CTAGE6

466

Q86UF2
WLAARTAERNLSDLR

CTAGE8

466

P0CG41
WLAARTAERNLSDLR

CTAGE9

466

A4FU28
WLAARTAERNLSDLR

CTAGE15

466

A4D2H0
EAEWREALRALRAAA

C8orf33

171

Q9H7E9
EAEVELSARRLRAWG

ALDH16A1

621

Q8IZ83
DLLSRWTADRLDAVV

AADAC

126

P22760
LTSDEAWKRFVRVAE

APOL4

56

Q9BPW4
SAISLAEDEEWKRIR

CYP3A5

116

P20815
QEAEWLVLLSRFDRL

HTR3B

401

O95264
ADERVLWLAQREAKA

ADGRA3

496

Q8IWK6
LERATFVANDLDWLL

ASCC2

56

Q9H1I8
RALDWVASANLLDDI

AJM1

961

C9J069
ALRLHDWSVEREAFL

ANKEF1

326

Q9NU02
KVEWERELCSLRFSL

ANKRD26

781

Q9UPS8
LLRDLRVDTKSRAAW

NPPC

71

P23582
REALLARLEWFEGQA

CCDC87

731

Q9NVE4
ASLWEARLEVTELSR

BBOF1

36

Q8ND07
EGAERKSLEDLARWR

CCDC154

436

A6NI56
LDWAELSRDLRKTCE

ASTN1

1271

O14525
FDRRWDDTILSSALA

GPRC5A

236

Q8NFJ5
ALTCDWAERILKRSF

RFX5

206

P48382
ELAARLLFSAVEWAR

NR2F1

221

P10589
WSRCSKEDLERFLRS

ADAMTS19

521

Q8TE59
WQRVFAALSDSRLLL

CDC42BPG

966

Q6DT37
RVWSLERRLAAAEET

PAXX

131

Q9BUH6
RKDAEAWFNERSATL

KRT26

271

Q7Z3Y9
SIFAWEIRDRLLSEG

PAX6

96

P26367
LGRWDLFREDLVRSA

POGLUT1

181

Q8NBL1
ELDTRKAIRQAFDVW

MMP24

181

Q9Y5R2
LRSQLEAIFLRDWDS

PLD3

456

Q8IV08
RDLVLWALDESFLQR

DCDC1

1466

M0R2J8
SERLFSLELLVDWVR

MAP10

6

Q9P2G4
ALWRRAITEAREEAK

MERTK

16

Q12866
GRDAELTRRFWALAS

HHIPL1

51

Q96JK4
LTRRFWALASRVDAA

HHIPL1

56

Q96JK4
LSLAFRTRDSEAWLL

CRB2

896

Q5IJ48
RTRDSEAWLLRAAAG

CRB2

901

Q5IJ48
ADAIRRIRNSKDSWD

DNAJC27

206

Q9NZQ0
ETLAEFWARLLERLF

GPC1

161

P35052
AFLRRAWRSGEDADL

HERC2

206

O95714
TELWENKRFLRAALS

GCNT2

26

Q8N0V5
AAAESERWELLLRRG

LONRF1

41

Q17RB8
LAARALRSFRWQSLE

FAM86C1P

21

Q9NVL1
LRSFRWQSLEAKLRD

FAM86C1P

26

Q9NVL1
DEWTRFARTLVEIRA

DYNC1I1

616

O14576
SAISIAEDEEWKRLR

CYP3A4

116

P08684
KAWAFDLSLEALRRT

MFSD6L

231

Q8IWD5
AELERRWESLVALSL

FGF4

41

P08620
EALARDLTKLDLRRW

MSTO1

521

Q9BUK6
LSKDDWREFRTLVIE

PDE1C

321

Q14123
LFRKEWSGLLEELAR

PFKP

136

Q01813
AELRVKFLQARDAWL

COG8

241

Q96MW5
RRDAETWFLSKTEEL

KRT16

301

P08779
TELELFKAACRWLRL

KLHL9

211

Q9P2J3
EADLKRWEAIREASR

LMO7

666

Q8WWI1
SRLGKLFWADSDLRR

LRP6

1111

O75581
LFWADSDLRRIESSD

LRP6

1116

O75581
LLQDARRARSWAEDE

LAMB2

1586

P55268
RSNEEAERLWLIAAD

LRP2BP

151

Q9P2M1
DLWEAALTYEASKRR

TUBGCP6

281

Q96RT7
AWDLLREATDKIREA

LAMA2

1786

P24043
KWEDLRRVAVESAEA

KCNU1

396

A8MYU2
WATALARRVAAELQA

AMH

371

P03971
REWLEVLEDTKRALS

EXOC8

271

Q8IYI6
RDEEALRALAWLRGT

SLC2A6

226

Q9UGQ3
RRLDELSAENRSLWE

IQSEC3

41

Q9UPP2
SADSRVKLWDVRRAS

ERCC8

206

Q13216
SFARDEIIWLLRHAD

NCKAP1

376

Q9Y2A7
LLEWLSEAEQTLRFR

MACF1

6781

Q9UPN3
ERSALDVASEQRRLW

SBF1

721

O95248
VTDRAARTLLWTELF

NDUFS8

51

O00217
EWFRVRLDRLSEAAK

NEFH

291

P12036
IFAWEIRDRLLADGV

PAX1

191

P15863
TRLFSVCDERWADDL

HCRTR1

196

O43613
LRWALDDVVAFRLNS

GAL3ST2

241

Q9H3Q3
WEDARRRALDVATFA

GALR3

176

O60755
AEEEELKEARRALSW

FRMD3

496

A2A2Y4
LSDRAWRDILALSNL

DNAH1

3566

Q9P2D7
WDFLSKETPARLARL

DTX3

26

Q8N9I9
QLLFAWRDKTARRED

EXOSC10

511

Q01780
ILSALRRMLWAADDF

IFI44

406

Q8TCB0
RRDSALTALDEETLW

CARD14

6

Q9BXL6
SALSFAEDEEWKRIR

CYP3A43

116

Q9HB55
LLRIRELEAWTTDFA

DNAH17

4301

Q9UFH2
TLIIAVDWFLDRLRT

SLC1A3

466

P43003
DFNTIDWVREKSRDR

CLCN5

86

P51795
RDSDLFLLDTRVVWA

BMP6

286

P22004
RDSCDVVLSERALRW

CERKL

56

Q49MI3
TLIIAVDWFLDRLRT

SLC1A6

491

P48664
LSRLLGDSTFEWVAR

EDEM1

316

Q92611
LLCEFSDRRLLDKWV

MAPKBP1

256

O60336
RLRETWALARDAALV

ANKS3

556

Q6ZW76
WALARDAALVLDQLR

ANKS3

561

Q6ZW76
TALLKSLSAERERWE

DYNC1H1

3476

Q14204
LESLDKWERLTVADA

PRKAR1A

256

P10644
RQIAWALRDLAVVDA

EXOC1

66

Q9NV70
RWFVLDAETRDLVSI

EML4

656

Q9HC35
DRSVRLWSLADHALI

EML6

346

Q6ZMW3
WGVRRRSLDSLDKCD

FRY

2481

Q5TBA9
LRWEDTRDTAAIFLI

DNAJC30

201

Q96LL9
AASLRLRARWESALD

DHX34

941

Q14147
DWLISRLERLEASSG

RYR2

556

Q92736
QAEDWLLRLRALAEE

DYSF

771

O75923
SVWRELALASQARLA

P2RX6

386

O15547
ESARREIALWFRADE

NME3

141

Q13232
ARNLRWADLLSEADP

PLA2G4D

31

Q86XP0
RLASRRSFWAELNVA

MOS

96

P00540
LDRVARAWFADLAEL

NYX

266

Q9GZU5
RELRDWGLSFDSNLL

PIWIL1

436

Q96J94
RKLTVEDFNRALRWS

TAF6L

61

Q9Y6J9
KRLLRSDAEAVSTRW

TAF7L

266

Q5H9L4
ESLARLQRAFARKWE

RGS7

151

P49802
ALKRLSTEEATRWAD

RGS8

41

P57771
TLFLRAKDEASARSW

SNTA1

246

Q13424
AWLHDSFREELRKLL

PRLHR

336

P49683
SRFEDWLKSAERTAA

SYNE2

6146

Q8WXH0
WATALAEGERDALRR

SYNM

76

O15061
NWLKARAAERAIAEE

MIA3

1601

Q5JRA6
SSDFLALAGLRAWRE

LRRC56

376

Q8IYG6
SLVRVDWEIFALLRA

PRAMEF14

421

Q5SWL7
ISRQSIDALKDWFRD

EIF5B

1186

O60841
ALSDAELGRWAELLS

PRR36

1296

Q9H6K5
WDTRIAKLRVSADSF

GINS2

121

Q9Y248
LDSDLWSRLEEKARA

RNF227

96

A6NIN4
LDWLDAETSRRTKEL

KIAA0753

641

Q2KHM9
QRDSKRWSRLEEFDV

DLC1

541

Q96QB1
SAEELCAWRRTLLES

URB1

1371

O60287
ARKAADWLFSADVSR

SARDH

586

Q9UL12
FADAAEAASWLRERR

SPTBN5

751

Q9NRC6
EAAWERLDQAIKART

SPTBN5

3191

Q9NRC6
ASLFLTAANRWLEVR

ABCC8

1236

Q09428
VLSWLRRDLEKSTAE

AKAP3

41

O75969
DAALSVAEWLRALHL

ARAP1

6

Q96P48
LVAREKVFWDLAATR

CLN8

56

Q9UBY8
RSLNLDWIALDADAV

NLRP9

916

Q7RTR0
FDICLARAKERWRSL

TBC1D14

426

Q9P2M4
KDRSLLLDWDRVRVF

TOP3B

251

O95985
ERRVASWAVSFERLL

RGS12

706

O14924
WERAAAVALFNLDIR

MIOS

521

Q9NXC5
SLALWTFRLLDENSD

TBC1D8B

861

Q0IIM8
ESEDAELLWRLARAS

RMDN1

111

Q96DB5
LETELADLDAAWRSF

SMC1B

336

Q8NDV3
ELRALWEETSFQLDR

PFAS

1006

O15067
WSAARRASREAVEKE

TEDC1

396

Q86SX3
LRSWVDTKARPFADL

WDFY4

731

Q6ZS81
EAKLLAAESWTRELE

ZNF646

686

O15015
DLFRALWRSLSREVK

NDUFAF2

6

Q8N183
WDELARVLVTLFDSR

NF1

1236

P21359
EELASKELAAWRRRE

PHF3

1016

Q92576
EETARTLWALSERLI

WWOX

391

Q9NZC7
RLRQFSDLWVRLEES

TRABD2A

431

Q86V40
RRAELEASRSLWALL

SPTBN4

636

Q9H254
AESWARDKERLLEAA

SPTBN4

656

Q9H254
AAAAWEERFSSLRRL

SPTBN4

2096

Q9H254
AAKLWFLTDRRIRED

RIMKLB

6

Q9ULI2
VAAWAVARATLADAR

PTH2R

291

P49190
VARATLADARCWELS

PTH2R

296

P49190
VEFIQEWALLDSARR

ZNF333

11

Q96JL9
ALAEDTEIWFLDRAL

TPGS2

166

Q68CL5
TKLSRREIDSWFSER

ZHX2

566

Q9Y6X8
EFRLVAADRRSWKIL

SLC30A6

21

Q6NXT4
LTADRDEKIRVSWAA

WDR4

161

P57081
VADDRLLRIWALELK

WSB2

311

Q9NYS7
WSLRNSKEERIDLDA

SLC5A1

561

P13866
DLSISDWLARERLRT

ARHGAP21

1846

Q5T5U3
AFEESLVARDWSRAL

ZFYVE26

1416

Q68DK2
ASLRSRLALQFVDRW

ZFYVE26

1471

Q68DK2
SFDVTDTVREWLLRR

TGFB3

201

P10600
WCSILEELRLDADRT

ZNF175

131

Q9Y473
WENFRTLTDLLLRFE

WFS1

371

O76024
LDLSAKRVAESWAFE

ZSWIM4

36

Q9H7M6
SRREELWACARTLAL

ZSWIM4

746

Q9H7M6
LVFWSDVTLDRILRA

LRP4

481

O75096
LDAERLASAVELWRG

MYO9B

1301

Q13459