Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionextracellular matrix structural constituent

LAMA2 LAMB1 SLIT2 HSPG2 FRAS1

6.93e-06188295GO:0005201
GeneOntologyMolecularFunctionheparin binding

SLIT2 PLA2G5 FGF10 FURIN CCN3

7.68e-06192295GO:0008201
GeneOntologyMolecularFunctionglycosaminoglycan binding

SLIT2 PLA2G5 FGF10 FURIN CCN3

3.83e-05268295GO:0005539
GeneOntologyMolecularFunctionsulfur compound binding

SLIT2 PLA2G5 FGF10 FURIN CCN3

9.27e-05323295GO:1901681
GeneOntologyMolecularFunctioncalcium ion binding

SLIT2 PLA2G5 HSPG2 MEGF6 MEGF8 ADGRE3

6.19e-04749296GO:0005509
GeneOntologyMolecularFunctiongrowth factor binding

ERBB2 EGFR FURIN

1.47e-03156293GO:0019838
GeneOntologyMolecularFunctionintegrin binding

LAMB1 EGFR CCN3

2.04e-03175293GO:0005178
GeneOntologyBiologicalProcesspositive regulation of cell differentiation

VWC2L BRINP2 LAMA2 LAMB1 SLIT2 PLA2G5 KDM4A MEGF8 EGFR CCN3

1.97e-0611412910GO:0045597
GeneOntologyBiologicalProcessaxon guidance

LAMA2 LAMB1 SLIT2 HSPG2 ERBB2 MEGF8

2.40e-06285296GO:0007411
GeneOntologyBiologicalProcessneuron projection guidance

LAMA2 LAMB1 SLIT2 HSPG2 ERBB2 MEGF8

2.45e-06286296GO:0097485
GeneOntologyBiologicalProcessepithelial cell proliferation

LAMB1 HSPG2 FGF10 ERBB2 DEAF1 EGFR CCN3

1.57e-05603297GO:0050673
GeneOntologyBiologicalProcesscellular response to growth factor stimulus

VWC2L KCP SLIT2 FGF10 ERBB2 MEGF8 EGFR FURIN

1.60e-05850298GO:0071363
GeneOntologyBiologicalProcessresponse to growth factor

VWC2L KCP SLIT2 FGF10 ERBB2 MEGF8 EGFR FURIN

2.10e-05883298GO:0070848
GeneOntologyBiologicalProcessenzyme-linked receptor protein signaling pathway

VWC2L KCP FGF10 ERBB2 MEGF8 EGFR ADGRE3 FURIN CCN3

2.34e-051186299GO:0007167
GeneOntologyBiologicalProcessgliogenesis

LAMA2 LAMB1 FGF10 ERBB2 KDM4A EGFR

2.68e-05435296GO:0042063
GeneOntologyBiologicalProcesspositive regulation of epithelial cell proliferation

LAMB1 HSPG2 FGF10 ERBB2 EGFR

3.40e-05270295GO:0050679
GeneOntologyBiologicalProcessregulation of low-density lipoprotein particle receptor catabolic process

FURIN MYLIP

3.99e-057292GO:0032803
GeneOntologyBiologicalProcesslow-density lipoprotein particle receptor catabolic process

FURIN MYLIP

3.99e-057292GO:0032802
GeneOntologyBiologicalProcesslow-density lipoprotein receptor particle metabolic process

FURIN MYLIP

3.99e-057292GO:0032799
GeneOntologyBiologicalProcessnegative regulation of monocyte chemotaxis

SLIT2 CCN3

3.99e-057292GO:0090027
GeneOntologyBiologicalProcesscell surface receptor protein serine/threonine kinase signaling pathway

VWC2L KCP FGF10 MEGF8 FURIN CCN3

4.75e-05482296GO:0007178
GeneOntologyBiologicalProcessERBB2-EGFR signaling pathway

ERBB2 EGFR

5.32e-058292GO:0038134
GeneOntologyBiologicalProcesscerebral cortex cell migration

LAMB1 SLIT2 EGFR

6.59e-0556293GO:0021795
GeneOntologyBiologicalProcessregulation of epithelial cell proliferation

LAMB1 HSPG2 FGF10 ERBB2 DEAF1 EGFR

6.78e-05514296GO:0050678
GeneOntologyBiologicalProcessglial cell differentiation

LAMA2 FGF10 ERBB2 KDM4A EGFR

7.73e-05321295GO:0010001
GeneOntologyBiologicalProcessneuron projection morphogenesis

LAMA2 LAMB1 SLIT2 HSPG2 ERBB2 MEGF8 EGFR

9.65e-05802297GO:0048812
GeneOntologyBiologicalProcessregulation of basement membrane organization

LAMA2 LAMB1

1.04e-0411292GO:0110011
GeneOntologyBiologicalProcessembryo development

LAMA2 SLIT2 HSPG2 FGF10 FRAS1 DEAF1 MEGF8 EGFR FURIN

1.05e-041437299GO:0009790
GeneOntologyBiologicalProcessplasma membrane bounded cell projection morphogenesis

LAMA2 LAMB1 SLIT2 HSPG2 ERBB2 MEGF8 EGFR

1.10e-04819297GO:0120039
GeneOntologyBiologicalProcessregulation of transmembrane receptor protein serine/threonine kinase signaling pathway

VWC2L KCP FGF10 FURIN CCN3

1.12e-04347295GO:0090092
GeneOntologyBiologicalProcessaxonogenesis

LAMA2 LAMB1 SLIT2 HSPG2 ERBB2 MEGF8

1.15e-04566296GO:0007409
GeneOntologyBiologicalProcesscell projection morphogenesis

LAMA2 LAMB1 SLIT2 HSPG2 ERBB2 MEGF8 EGFR

1.16e-04826297GO:0048858
GeneOntologyBiologicalProcesstube morphogenesis

SLIT2 HSPG2 FGF10 ERBB2 DEAF1 MEGF8 EGFR CCN3

1.17e-041125298GO:0035239
GeneOntologyBiologicalProcessnegative regulation of multicellular organismal process

SLIT2 PLA2G5 HSPG2 ERBB2 KDM4A EGFR FURIN CCN3 MYLIP

1.38e-041488299GO:0051241
GeneOntologyBiologicalProcesstelencephalon cell migration

LAMB1 SLIT2 EGFR

1.40e-0472293GO:0022029
GeneOntologyBiologicalProcessforebrain cell migration

LAMB1 SLIT2 EGFR

1.58e-0475293GO:0021885
GeneOntologyBiologicalProcesspositive regulation of integrin-mediated signaling pathway

LAMA2 LAMB1

1.72e-0414292GO:2001046
GeneOntologyBiologicalProcessregulation of receptor catabolic process

FURIN MYLIP

1.72e-0414292GO:2000644
GeneOntologyBiologicalProcesscentral nervous system development

BRINP2 LAMB1 SLIT2 HSPG2 FGF10 ERBB2 KDM4A EGFR

1.80e-041197298GO:0007417
GeneOntologyBiologicalProcessmorphogenesis of an epithelium

SLIT2 FGF10 FRAS1 DEAF1 MEGF8 EGFR

1.88e-04619296GO:0002009
GeneOntologyBiologicalProcessmammary gland epithelium development

SLIT2 FGF10 DEAF1

2.21e-0484293GO:0061180
GeneOntologyBiologicalProcessaxon development

LAMA2 LAMB1 SLIT2 HSPG2 ERBB2 MEGF8

2.29e-04642296GO:0061564
GeneOntologyBiologicalProcessregulation of cellular response to growth factor stimulus

VWC2L KCP SLIT2 FGF10 FURIN

2.48e-04412295GO:0090287
GeneOntologyBiologicalProcessanimal organ morphogenesis

LAMA2 LAMB1 SLIT2 HSPG2 FGF10 FRAS1 MEGF8 EGFR

2.69e-041269298GO:0009887
GeneOntologyBiologicalProcessneuron projection development

LAMA2 LAMB1 SLIT2 HSPG2 ERBB2 MEGF8 EGFR MYLIP

2.93e-041285298GO:0031175
GeneOntologyBiologicalProcessmetanephros development

SLIT2 FGF10 FRAS1

3.17e-0495293GO:0001656
GeneOntologyBiologicalProcessregulation of chemotaxis

SLIT2 FGF10 MEGF8 CCN3

3.49e-04242294GO:0050920
GeneOntologyBiologicalProcesstransforming growth factor beta receptor superfamily signaling pathway

VWC2L KCP FGF10 MEGF8 FURIN

3.54e-04445295GO:0141091
GeneOntologyBiologicalProcessregulation of locomotion

LAMA2 LAMB1 SLIT2 FGF10 MEGF8 EGFR FURIN CCN3

3.65e-041327298GO:0040012
GeneOntologyBiologicalProcessregulation of plasma lipoprotein particle levels

PLA2G5 FURIN MYLIP

4.02e-04103293GO:0097006
GeneOntologyBiologicalProcessregeneration

HSPG2 FGF10 EGFR CCN3

4.06e-04252294GO:0031099
GeneOntologyBiologicalProcessaxon extension involved in axon guidance

SLIT2 MEGF8

4.33e-0422292GO:0048846
GeneOntologyBiologicalProcessneuron projection extension involved in neuron projection guidance

SLIT2 MEGF8

4.33e-0422292GO:1902284
GeneOntologyBiologicalProcessregulation of integrin-mediated signaling pathway

LAMA2 LAMB1

4.74e-0423292GO:2001044
GeneOntologyBiologicalProcessnegative regulation of leukocyte chemotaxis

SLIT2 CCN3

4.74e-0423292GO:0002689
GeneOntologyBiologicalProcesspositive regulation of locomotion

LAMB1 SLIT2 FGF10 MEGF8 EGFR FURIN

4.97e-04742296GO:0040017
GeneOntologyBiologicalProcesscell morphogenesis involved in neuron differentiation

LAMA2 LAMB1 SLIT2 HSPG2 ERBB2 MEGF8

5.18e-04748296GO:0048667
GeneOntologyBiologicalProcesstissue morphogenesis

SLIT2 FGF10 FRAS1 DEAF1 MEGF8 EGFR

5.26e-04750296GO:0048729
GeneOntologyBiologicalProcesstube development

SLIT2 HSPG2 FGF10 ERBB2 DEAF1 MEGF8 EGFR CCN3

5.28e-041402298GO:0035295
GeneOntologyBiologicalProcesspositive regulation of Ras protein signal transduction

FGF10 ERBB2

5.61e-0425292GO:0046579
GeneOntologyBiologicalProcesscell-cell adhesion

LAMB1 SLIT2 PLA2G5 ERBB2 EGFR CCN3 PEAR1

5.88e-041077297GO:0098609
GeneOntologyBiologicalProcessERBB2 signaling pathway

ERBB2 EGFR

6.56e-0427292GO:0038128
GeneOntologyBiologicalProcesspositive regulation of neuron differentiation

VWC2L BRINP2 KDM4A

6.75e-04123293GO:0045666
GeneOntologyBiologicalProcessneuron development

LAMA2 LAMB1 SLIT2 HSPG2 ERBB2 MEGF8 EGFR MYLIP

7.01e-041463298GO:0048666
GeneOntologyBiologicalProcessregulation of cell growth

SLIT2 ERBB2 MEGF8 EGFR CCN3

7.13e-04519295GO:0001558
GeneOntologyBiologicalProcessmetanephros morphogenesis

FGF10 FRAS1

7.57e-0429292GO:0003338
GeneOntologyBiologicalProcessmorphogenesis of an epithelial fold

FGF10 EGFR

7.57e-0429292GO:0060571
GeneOntologyBiologicalProcessblood vessel morphogenesis

SLIT2 HSPG2 FGF10 ERBB2 MEGF8 CCN3

8.24e-04817296GO:0048514
GeneOntologyBiologicalProcessreceptor catabolic process

FURIN MYLIP

8.65e-0431292GO:0032801
GeneOntologyBiologicalProcessregulation of monocyte chemotaxis

SLIT2 CCN3

9.22e-0432292GO:0090025
GeneOntologyBiologicalProcessepidermal growth factor receptor signaling pathway

ERBB2 EGFR ADGRE3

9.63e-04139293GO:0007173
GeneOntologyBiologicalProcesscell morphogenesis

LAMA2 LAMB1 SLIT2 HSPG2 ERBB2 MEGF8 EGFR

1.08e-031194297GO:0000902
GeneOntologyBiologicalProcessmotor neuron axon guidance

SLIT2 ERBB2

1.10e-0335292GO:0008045
GeneOntologyBiologicalProcesscerebral cortex development

LAMB1 SLIT2 EGFR

1.13e-03147293GO:0021987
GeneOntologyBiologicalProcessembryonic skeletal system development

HSPG2 DEAF1 MEGF8

1.15e-03148293GO:0048706
GeneOntologyBiologicalProcessplasma lipoprotein particle remodeling

PLA2G5 FURIN

1.17e-0336292GO:0034369
GeneOntologyBiologicalProcessprotein-lipid complex remodeling

PLA2G5 FURIN

1.17e-0336292GO:0034368
GeneOntologyBiologicalProcessnegative regulation of cell differentiation

SLIT2 FGF10 ERBB2 KDM4A EGFR CCN3

1.18e-03875296GO:0045596
GeneOntologyBiologicalProcessregulation of cell migration

LAMA2 LAMB1 SLIT2 FGF10 EGFR FURIN CCN3

1.18e-031211297GO:0030334
GeneOntologyBiologicalProcessnegative regulation of developmental process

SLIT2 HSPG2 FGF10 ERBB2 KDM4A EGFR CCN3

1.23e-031220297GO:0051093
GeneOntologyBiologicalProcessdigestive tract development

FGF10 MEGF8 EGFR

1.25e-03152293GO:0048565
GeneOntologyBiologicalProcesssalivary gland morphogenesis

FGF10 EGFR

1.30e-0338292GO:0007435
GeneOntologyBiologicalProcessnegative regulation of mononuclear cell migration

SLIT2 CCN3

1.37e-0339292GO:0071676
GeneOntologyBiologicalProcessprotein-containing complex remodeling

PLA2G5 FURIN

1.37e-0339292GO:0034367
GeneOntologyBiologicalProcesschordate embryonic development

SLIT2 HSPG2 DEAF1 MEGF8 EGFR FURIN

1.41e-03906296GO:0043009
GeneOntologyBiologicalProcessERBB signaling pathway

ERBB2 EGFR ADGRE3

1.44e-03160293GO:0038127
GeneOntologyBiologicalProcessmammary gland development

SLIT2 FGF10 DEAF1

1.50e-03162293GO:0030879
GeneOntologyBiologicalProcessphagocytosis, recognition

PLA2G5 PEAR1

1.59e-0342292GO:0006910
GeneOntologyBiologicalProcessblood vessel development

SLIT2 HSPG2 FGF10 ERBB2 MEGF8 CCN3

1.60e-03929296GO:0001568
GeneOntologyBiologicalProcessembryo development ending in birth or egg hatching

SLIT2 HSPG2 DEAF1 MEGF8 EGFR FURIN

1.60e-03929296GO:0009792
GeneOntologyBiologicalProcesspositive regulation of chemotaxis

SLIT2 FGF10 MEGF8

1.60e-03166293GO:0050921
GeneOntologyBiologicalProcessregulation of cell motility

LAMA2 LAMB1 SLIT2 FGF10 EGFR FURIN CCN3

1.63e-031280297GO:2000145
GeneOntologyBiologicalProcessdigestive system development

FGF10 MEGF8 EGFR

1.63e-03167293GO:0055123
GeneOntologyBiologicalProcesscell growth

SLIT2 ERBB2 MEGF8 EGFR CCN3

1.63e-03625295GO:0016049
GeneOntologyCellularComponentextracellular matrix

LAMA2 LAMB1 SLIT2 HSPG2 FGF10 FRAS1 MUC5B MEGF6 CCN3

2.21e-07656309GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

LAMA2 LAMB1 SLIT2 HSPG2 FGF10 FRAS1 MUC5B MEGF6 CCN3

2.27e-07658309GO:0030312
GeneOntologyCellularComponentcollagen-containing extracellular matrix

LAMA2 LAMB1 SLIT2 HSPG2 FGF10 FRAS1 MEGF6 CCN3

5.80e-07530308GO:0062023
GeneOntologyCellularComponentkeratin filament

KRTAP4-16 KRTAP10-1 KRTAP10-6 KRTAP10-8

1.09e-0597304GO:0045095
GeneOntologyCellularComponentbasement membrane

LAMA2 LAMB1 HSPG2 FRAS1

2.69e-05122304GO:0005604
GeneOntologyCellularComponentprotein complex involved in cell-matrix adhesion

LAMA2 LAMB1

2.67e-0417302GO:0098637
GeneOntologyCellularComponentintermediate filament

KRTAP4-16 KRTAP10-1 KRTAP10-6 KRTAP10-8

2.97e-04227304GO:0005882
GeneOntologyCellularComponentGolgi lumen

HSPG2 MUC5B FURIN

5.05e-04109303GO:0005796
GeneOntologyCellularComponentintermediate filament cytoskeleton

KRTAP4-16 KRTAP10-1 KRTAP10-6 KRTAP10-8

5.19e-04263304GO:0045111
GeneOntologyCellularComponentprotein complex involved in cell adhesion

LAMA2 LAMB1

3.24e-0359302GO:0098636
GeneOntologyCellularComponentcell surface

SLIT2 PLA2G5 FGF10 EGFR ADGRE3 FURIN

4.40e-031111306GO:0009986
HumanPhenoAlveolar cell carcinoma

ERBB2 MUC5B EGFR

6.01e-0618113HP:0006519
HumanPhenoNeoplasm of the tracheobronchial system

ERBB2 MUC5B EGFR

1.13e-0522113HP:0100552
HumanPhenoHorizontal eyebrow

HSPG2 DEAF1 EGFR

4.32e-0534113HP:0011228
HumanPhenoAbnormal lacrimal duct morphology

FGF10 FRAS1 MEGF8

1.39e-0450113HP:0011481
MousePhenomicrophthalmia

VWC2L SLIT2 HSPG2 FGF10 FRAS1 MEGF8 EGFR

1.26e-06362237MP:0001297
MousePhenoabnormal eye size

VWC2L SLIT2 HSPG2 FGF10 FRAS1 MEGF8 EGFR

1.60e-06375237MP:0002697
MousePhenoabnormal Schwann cell morphology

LAMA2 HSPG2 ERBB2

2.91e-0537233MP:0001106
MousePhenoabnormal PNS glial cell morphology

LAMA2 HSPG2 ERBB2

2.91e-0537233MP:0001105
MousePhenoabnormal respiration

LAMA2 HSPG2 FGF10 ERBB2 FRAS1 MUC5B EGFR

3.41e-05598237MP:0001943
MousePhenoabnormal basement membrane morphology

LAMA2 HSPG2 FRAS1

3.69e-0540233MP:0004272
MousePhenoabnormal blood vessel morphology

SLIT2 HSPG2 FGF10 ERBB2 FRAS1 MEGF8 EGFR IER5L FURIN CCN3

5.12e-0514722310MP:0001614
MousePhenoabnormal submandibular gland development

FGF10 EGFR

5.41e-057232MP:0013541
MousePhenocleft palate

HSPG2 FGF10 FRAS1 MEGF8 EGFR

9.04e-05289235MP:0000111
MousePhenooral cleft

HSPG2 FGF10 FRAS1 MEGF8 EGFR

9.34e-05291235MP:0021164
MousePhenolimbs/digits/tail phenotype

NFXL1 LAMB1 HSPG2 FGF10 FRAS1 MEGF8 EGFR FURIN CCN3

9.59e-051258239MP:0005371
MousePhenoabnormal ureteric bud morphology

SLIT2 FGF10 FRAS1

1.07e-0457233MP:0006032
MousePhenoabnormal pectoral girdle bone morphology

HSPG2 FGF10 FRAS1 DEAF1 MEGF8

1.10e-04301235MP:0004508
MousePhenoeyelids open at birth

FGF10 FRAS1 EGFR

1.13e-0458233MP:0001302
MousePhenopetechiae

MEGF8 EGFR

1.41e-0411232MP:0008816
MousePhenoabnormal palate morphology

HSPG2 FGF10 FRAS1 MEGF8 EGFR

1.48e-04321235MP:0003755
MousePhenoabnormal limb morphology

NFXL1 HSPG2 FGF10 FRAS1 MEGF8 EGFR FURIN CCN3

1.50e-041028238MP:0002109
MousePhenoabsent eyelids

FRAS1 EGFR

1.69e-0412232MP:0001341
MousePhenoabnormal vein morphology

HSPG2 FGF10 FURIN CCN3

1.78e-04176234MP:0002725
MousePhenoabnormal heart ventricle morphology

SLIT2 HSPG2 ERBB2 FRAS1 MEGF8 EGFR CCN3

2.03e-04793237MP:0005294
MousePhenoabnormal cranium morphology

LAMA2 HSPG2 FGF10 FRAS1 MEGF8 EGFR CCN3

2.36e-04813237MP:0000438
MousePhenoabnormal digestive system development

SLIT2 FGF10 FURIN

2.43e-0475233MP:0003119
MousePhenoabnormal craniofacial bone morphology

LAMA2 HSPG2 FGF10 FRAS1 MEGF8 EGFR CCN3

2.63e-04827237MP:0002116
MousePhenoabnormal hindlimb morphology

NFXL1 HSPG2 FGF10 FRAS1 EGFR CCN3

2.64e-04576236MP:0000556
MousePhenoabnormal heart development

HSPG2 ERBB2 MEGF8 FURIN CCN3

2.94e-04372235MP:0000267
MousePhenoabnormal chondrocyte morphology

HSPG2 EGFR CCN3

3.28e-0483233MP:0000166
MousePhenoabnormal joint mobility

LAMA2 CCN3

3.47e-0417232MP:0008069
MousePhenoabnormal autopod morphology

FRAS1 MEGF8 EGFR FURIN CCN3

3.66e-04390235MP:0000572
MousePhenoabnormal respiratory function

LAMA2 FGF10 FRAS1 MUC5B EGFR

4.06e-04399235MP:0002327
MousePhenoabnormal appendicular skeleton morphology

NFXL1 HSPG2 FGF10 FRAS1 DEAF1 MEGF8 CCN3

4.29e-04896237MP:0009250
MousePhenoabnormal respiratory system physiology

LAMA2 HSPG2 FGF10 ERBB2 FRAS1 MUC5B EGFR

4.32e-04897237MP:0002133
MousePhenoabnormal sensory neuron innervation pattern

FGF10 ERBB2 EGFR

4.44e-0492233MP:0000968
MousePhenoabnormal aorta morphology

SLIT2 HSPG2 MEGF8 EGFR

4.55e-04225234MP:0000272
MousePhenoabnormal kidney development

SLIT2 FGF10 FRAS1

4.58e-0493233MP:0000527
MousePhenoexencephaly

HSPG2 DEAF1 MEGF8 FURIN

4.94e-04230234MP:0000914
MousePhenoabnormal heart ventricle outflow tract morphology

HSPG2 MEGF8 EGFR

5.03e-0496233MP:0010224
MousePhenoabnormal cranium size

LAMA2 HSPG2 CCN3

5.19e-0497233MP:0010031
MousePhenoabnormal eyelid morphology

HSPG2 FGF10 FRAS1 EGFR

5.19e-04233234MP:0001340
MousePhenoflaky skin

FRAS1 EGFR

5.34e-0421232MP:0001195
MousePhenoabnormal extracellular matrix morphology

LAMA2 HSPG2 FRAS1

5.67e-04100233MP:0013258
MousePhenoabnormal glossopharyngeal nerve morphology

ERBB2 MEGF8

5.86e-0422232MP:0001073
MousePhenoabnormal artery morphology

SLIT2 HSPG2 FGF10 MEGF8 EGFR

6.35e-04440235MP:0002191
MousePhenoabnormal axon fasciculation

ERBB2 MEGF8

6.42e-0423232MP:0009450
MousePhenoabnormal sternum morphology

HSPG2 FRAS1 DEAF1 MEGF8

7.29e-04255234MP:0000157
MousePhenoabnormal urinary system development

SLIT2 FGF10 FRAS1

7.69e-04111233MP:0003942
MousePhenoabnormal submandibular gland morphology

FGF10 EGFR

8.22e-0426232MP:0003793
MousePhenoabnormal ear morphology

LAMA2 HSPG2 FGF10 MUC5B EGFR

8.57e-04470235MP:0002102
MousePhenoabnormal cardinal vein morphology

HSPG2 FURIN

9.54e-0428232MP:0004783
MousePhenoabnormal coronary artery morphology

HSPG2 MEGF8

1.02e-0329232MP:0004111
MousePhenoabnormal vagus nerve morphology

ERBB2 MEGF8

1.02e-0329232MP:0001074
MousePhenodelayed bone ossification

HSPG2 MEGF8 CCN3

1.14e-03127233MP:0000060
MousePhenoabnormal heartbeat

BRINP2 PLA2G5 HSPG2 ERBB2 EGFR

1.14e-03501235MP:0004085
MousePhenoperinatal lethality, incomplete penetrance

LAMA2 SLIT2 HSPG2 DEAF1 EGFR

1.16e-03503235MP:0011090
MousePhenoabnormal thoracic aorta morphology

SLIT2 HSPG2 MEGF8

1.33e-03134233MP:0010468
MousePhenoabnormal bronchus morphology

FGF10 EGFR

1.33e-0333232MP:0002264
MousePhenothin epidermis

FGF10 EGFR

1.33e-0333232MP:0001218
MousePhenoabnormal systemic artery morphology

SLIT2 HSPG2 MEGF8 EGFR

1.40e-03304234MP:0011655
MousePhenosmall pancreas

FGF10 EGFR

1.41e-0334232MP:0004247
MousePhenoabnormal branching involved in lung morphogenesis

FGF10 EGFR

1.41e-0334232MP:0011024
MousePhenoabnormal jaw morphology

HSPG2 FGF10 FRAS1 MEGF8 EGFR

1.47e-03530235MP:0000454
MousePhenoprolonged RR interval

BRINP2 PLA2G5 EGFR

1.47e-03139233MP:0010506
MousePhenoabnormal limb development

FGF10 FRAS1 MEGF8

1.50e-03140233MP:0006279
MousePhenoabnormal muscle morphology

LAMA2 HSPG2 FGF10 ERBB2 MEGF8 EGFR CCN3

1.51e-031106237MP:0002108
MousePhenoabnormal lung development

FGF10 FRAS1 EGFR

1.57e-03142233MP:0001176
MousePhenoabnormal axial skeleton morphology

LAMA2 HSPG2 FGF10 FRAS1 DEAF1 MEGF8 EGFR CCN3

1.60e-031458238MP:0002114
MousePhenosmall snout

HSPG2 MEGF8 EGFR

1.63e-03144233MP:0030190
MousePhenoabnormal joint physiology

LAMA2 HSPG2 CCN3

1.66e-03145233MP:0031169
MousePhenoabnormal major salivary gland morphology

FGF10 EGFR

1.67e-0337232MP:0003792
MousePhenoperinatal lethality

LAMA2 SLIT2 HSPG2 FGF10 ERBB2 DEAF1 EGFR

1.71e-031130237MP:0002081
MousePhenopreaxial polydactyly

FRAS1 MEGF8

1.85e-0339232MP:0009743
MousePhenoabnormal chest morphology

HSPG2 CCN3

1.85e-0339232MP:0004134
MousePhenoabnormal body wall morphology

MEGF8 FURIN CCN3

1.87e-03151233MP:0003385
MousePhenodecreased hair follicle number

FGF10 EGFR

2.04e-0341232MP:0000379
MousePhenoincreased compact bone thickness

HSPG2 CCN3

2.04e-0341232MP:0004148
MousePhenoabnormal heart right ventricle morphology

SLIT2 HSPG2 MEGF8

2.05e-03156233MP:0003920
MousePhenoabnormal interventricular septum morphology

SLIT2 FRAS1 MEGF8 CCN3

2.16e-03342234MP:0000281
MousePhenoabnormal respiratory system development

FGF10 FRAS1 EGFR

2.20e-03160233MP:0003115
MousePhenoabnormal RR interval

BRINP2 PLA2G5 EGFR

2.20e-03160233MP:0010504
MousePhenoincreased variability of skeletal muscle fiber size

LAMA2 HSPG2

2.24e-0343232MP:0009403
MousePhenoabnormal heart valve morphology

HSPG2 MEGF8 EGFR

2.32e-03163233MP:0000285
MousePhenoimpaired lung alveolus development

FGF10 EGFR

2.35e-0344232MP:0006027
MousePhenorespiratory failure

HSPG2 ERBB2 EGFR

2.40e-03165233MP:0001953
MousePhenoabnormal viscerocranium morphology

HSPG2 FGF10 FRAS1 MEGF8 EGFR

2.41e-03593235MP:0005274
MousePhenoabnormal skin adnexa physiology

FGF10 FRAS1 EGFR

2.49e-03167233MP:0010680
MousePhenodecreased respiration

HSPG2 ERBB2 EGFR

2.62e-03170233MP:0014274
MousePhenotransposition of great arteries

HSPG2 MEGF8

2.68e-0347232MP:0004110
MousePhenoabnormal vestibular hair cell morphology

LAMA2 FGF10

2.79e-0348232MP:0002623
MousePhenoabnormal digestive system morphology

SLIT2 HSPG2 FGF10 FRAS1 MEGF8 EGFR FURIN

2.83e-031233237MP:0000462
MousePhenoabnormal lung alveolus development

FGF10 EGFR

3.02e-0350232MP:0010995
MousePhenonarrow eye opening

FGF10 FRAS1

3.02e-0350232MP:0005287
DomainGrowth_fac_rcpt_

LAMB1 HSPG2 ERBB2 FRAS1 MEGF6 MEGF8 EGFR ADGRE3 FURIN CCN3

2.16e-141562910IPR009030
DomainEGF

BRINP2 LAMA2 LAMB1 SLIT2 HSPG2 FRAS1 MEGF6 MEGF8 ADGRE3 PEAR1

1.33e-122352910SM00181
DomainLaminin_EGF

LAMA2 LAMB1 HSPG2 MEGF6 MEGF8 PEAR1

1.27e-1135296PF00053
DomainEGF_Lam

LAMA2 LAMB1 HSPG2 MEGF6 MEGF8 PEAR1

1.27e-1135296SM00180
DomainLaminin_EGF

LAMA2 LAMB1 HSPG2 MEGF6 MEGF8 PEAR1

2.15e-1138296IPR002049
DomainEGF-like_dom

LAMA2 LAMB1 SLIT2 HSPG2 FRAS1 MEGF6 MEGF8 ADGRE3 PEAR1

9.14e-11249299IPR000742
DomainVWFC_1

VWC2L KCP FRAS1 MUC5B CCN3

2.29e-0936295PS01208
DomainVWC

VWC2L KCP FRAS1 MUC5B CCN3

3.04e-0938295SM00214
DomainVWFC_2

VWC2L KCP FRAS1 MUC5B CCN3

3.04e-0938295PS50184
DomainVWF_dom

VWC2L KCP FRAS1 MUC5B CCN3

5.13e-0942295IPR001007
DomainFurin_repeat

ERBB2 FRAS1 EGFR FURIN

1.41e-0818294IPR006212
DomainFU

ERBB2 FRAS1 EGFR FURIN

1.41e-0818294SM00261
DomainVWC

KCP FRAS1 MUC5B CCN3

9.35e-0828294PF00093
DomainEGF_1

LAMA2 LAMB1 SLIT2 HSPG2 MEGF6 MEGF8 PEAR1

9.84e-08255297PS00022
DomainEGF-like_CS

LAMA2 LAMB1 SLIT2 HSPG2 MEGF6 MEGF8 PEAR1

1.15e-07261297IPR013032
DomainEGF_LAM_2

LAMA2 LAMB1 HSPG2 MEGF8

1.25e-0730294PS50027
DomainEGF_LAM_1

LAMA2 LAMB1 HSPG2 MEGF8

1.25e-0730294PS01248
DomainEGF_2

LAMA2 LAMB1 SLIT2 HSPG2 MEGF6 MEGF8 PEAR1

1.28e-07265297PS01186
DomainLaminin_G_1

LAMA2 SLIT2 HSPG2

5.51e-0711293PF00054
DomainEGF_CA

SLIT2 HSPG2 MEGF6 MEGF8 ADGRE3

1.15e-06122295SM00179
DomainEGF-like_Ca-bd_dom

SLIT2 HSPG2 MEGF6 MEGF8 ADGRE3

1.24e-06124295IPR001881
DomainEGF_3

SLIT2 HSPG2 MEGF6 MEGF8 ADGRE3 PEAR1

1.39e-06235296PS50026
DomainVWFD

KCP MUC5B SUSD2

1.86e-0616293PS51233
DomainVWD

KCP MUC5B SUSD2

1.86e-0616293SM00216
DomainVWF_type-D

KCP MUC5B SUSD2

1.86e-0616293IPR001846
DomainVWD

KCP MUC5B SUSD2

1.86e-0616293PF00094
DomainCTCK_1

SLIT2 MUC5B CCN3

2.70e-0618293PS01185
DomainVWC_out

KCP FRAS1 MUC5B

3.21e-0619293SM00215
DomainCT

SLIT2 MUC5B CCN3

5.08e-0622293SM00041
DomainCys_knot_C

SLIT2 MUC5B CCN3

7.57e-0625293IPR006207
DomainCTCK_2

SLIT2 MUC5B CCN3

7.57e-0625293PS01225
DomainTyr_kinase_EGF/ERB/XmrK_rcpt

ERBB2 EGFR

1.39e-054292IPR016245
DomainEGF_Ca-bd_CS

SLIT2 MEGF6 MEGF8 ADGRE3

1.47e-0597294IPR018097
DomainEGF_CA

SLIT2 MEGF6 MEGF8 ADGRE3

1.59e-0599294PS01187
DomainASX_HYDROXYL

SLIT2 MEGF6 MEGF8 ADGRE3

1.66e-05100294PS00010
DomainEGF-type_Asp/Asn_hydroxyl_site

SLIT2 MEGF6 MEGF8 ADGRE3

2.09e-05106294IPR000152
DomainLAM_G_DOMAIN

LAMA2 SLIT2 HSPG2

2.74e-0538293PS50025
DomainKeratin_B2_2

KRTAP10-1 KRTAP10-6 KRTAP10-8

2.96e-0539293PF13885
DomainLaminin_G_2

LAMA2 SLIT2 HSPG2

3.20e-0540293PF02210
DomainGF_recep_IV

ERBB2 EGFR

3.48e-056292PF14843
DomainGF_recep_IV

ERBB2 EGFR

3.48e-056292IPR032778
DomainLamG

LAMA2 SLIT2 HSPG2

4.27e-0544293SM00282
DomainFurin-like

ERBB2 EGFR

4.87e-057292PF00757
DomainRcpt_L-dom

ERBB2 EGFR

4.87e-057292IPR000494
DomainFurin-like_Cys-rich_dom

ERBB2 EGFR

4.87e-057292IPR006211
DomainRecep_L_domain

ERBB2 EGFR

4.87e-057292PF01030
Domain-

ERBB2 EGFR

4.87e-0572923.80.20.20
DomainLAMININ_IVA

LAMA2 HSPG2

6.48e-058292PS51115
DomainLaminin_B

LAMA2 HSPG2

6.48e-058292PF00052
DomainLamB

LAMA2 HSPG2

6.48e-058292SM00281
DomainLaminin_IV

LAMA2 HSPG2

6.48e-058292IPR000034
DomainLaminin_G

LAMA2 SLIT2 HSPG2

9.81e-0558293IPR001791
DomainKAP

KRTAP10-1 KRTAP10-6 KRTAP10-8

9.81e-0558293IPR002494
DomainUnchr_dom_Cys-rich

KCP MUC5B

1.80e-0413292IPR014853
DomainC8

KCP MUC5B

1.80e-0413292SM00832
DomainTIL_dom

KCP MUC5B

2.09e-0414292IPR002919
DomainGlyco_hormone_CN

MUC5B CCN3

2.41e-0415292IPR006208
DomainCys_knot

MUC5B CCN3

2.41e-0415292PF00007
DomainLAMININ_NTER

LAMA2 LAMB1

2.76e-0416292PS51117
DomainLaminin_N

LAMA2 LAMB1

2.76e-0416292PF00055
DomainEMI_domain

MEGF6 PEAR1

2.76e-0416292IPR011489
DomainLaminin_N

LAMA2 LAMB1

2.76e-0416292IPR008211
DomainLamNT

LAMA2 LAMB1

2.76e-0416292SM00136
DomainEMI

MEGF6 PEAR1

3.12e-0417292PS51041
DomainEGF_CA

MEGF6 MEGF8 ADGRE3

3.16e-0486293PF07645
DomainGalactose-bd-like

LAMA2 LAMB1 FURIN

4.10e-0494293IPR008979
Domain-

LAMA2 SLIT2 HSPG2

4.23e-04952932.60.120.200
DomainhEGF

SLIT2 MEGF6

8.58e-0428292PF12661
DomainEGF

SLIT2 HSPG2 MEGF6

9.64e-04126293PF00008
DomainKeratin_B2

KRTAP10-1 KRTAP10-6

1.75e-0340292PF01500
DomainConA-like_dom

LAMA2 SLIT2 HSPG2

4.64e-03219293IPR013320
Domain-

LAMA2 FURIN

5.71e-03732922.60.120.260
DomainTyrKc

ERBB2 EGFR

8.20e-0388292SM00219
DomainTyr_kinase_cat_dom

ERBB2 EGFR

8.20e-0388292IPR020635
PathwayPID_A6B1_A6B4_INTEGRIN_PATHWAY

LAMA2 LAMB1 ERBB2 EGFR

5.70e-0746214M239
PathwayWP_ALPHA_6_BETA_4_INTEGRIN_SIGNALING_PATHWAY

LAMA2 LAMB1 ERBB2 EGFR

2.47e-0666214MM15925
PathwayREACTOME_RESPIRATORY_SYNCYTIAL_VIRUS_RSV_ATTACHMENT_AND_ENTRY

HSPG2 EGFR FURIN

4.95e-0623213M48234
PathwayREACTOME_LAMININ_INTERACTIONS

LAMA2 LAMB1 HSPG2

1.13e-0530213M27216
PathwayREACTOME_DEVELOPMENTAL_BIOLOGY

LAMA2 LAMB1 SLIT2 FGF10 ERBB2 EGFR KRTAP10-1 FURIN KRTAP10-6 KRTAP10-8

1.40e-0514322110M509
PathwayKEGG_MEDICUS_VARIANT_ERBB2_OVEREXPRESSION_TO_EGF_JAK_STAT_SIGNALING_PATHWAY

ERBB2 EGFR

4.42e-057212M47431
PathwayREACTOME_DEVELOPMENTAL_BIOLOGY

SLIT2 ERBB2 EGFR KRTAP10-1 KRTAP10-6 KRTAP10-8

6.80e-05502216MM14537
PathwayKEGG_MEDICUS_REFERENCE_RTK_PLCG_ITPR_SIGNALING_PATHWAY

FGF10 ERBB2 EGFR

7.11e-0555213M47952
PathwayREACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS

LAMA2 LAMB1 HSPG2

8.78e-0559213M27218
PathwayREACTOME_SIGNALING_BY_RECEPTOR_TYROSINE_KINASES

LAMA2 LAMB1 FGF10 ERBB2 EGFR FURIN

9.39e-05532216M27870
PathwayKEGG_PATHWAYS_IN_CANCER

LAMA2 LAMB1 FGF10 ERBB2 EGFR

9.48e-05325215M12868
PathwayPID_INTEGRIN4_PATHWAY

LAMA2 LAMB1

1.15e-0411212M158
PathwayREACTOME_ERBB2_ACTIVATES_PTK6_SIGNALING

ERBB2 EGFR

1.15e-0411212MM15478
PathwayKEGG_MEDICUS_VARIANT_ERBB2_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY

ERBB2 EGFR

1.38e-0412212M47393
PathwayWP_FOCAL_ADHESION

LAMA2 LAMB1 ERBB2 EGFR

1.50e-04187214MM15913
PathwayREACTOME_ERBB2_ACTIVATES_PTK6_SIGNALING

ERBB2 EGFR

1.63e-0413212M27729
PathwayREACTOME_ERBB2_REGULATES_CELL_MOTILITY

ERBB2 EGFR

1.63e-0413212MM15320
PathwayREACTOME_ECM_PROTEOGLYCANS

LAMA2 LAMB1 HSPG2

1.87e-0476213M27219
PathwayREACTOME_PI3K_EVENTS_IN_ERBB2_SIGNALING

ERBB2 EGFR

1.90e-0414212MM14761
PathwayREACTOME_SHC1_EVENTS_IN_ERBB2_SIGNALING

ERBB2 EGFR

1.90e-0414212MM14531
PathwayWP_FOCAL_ADHESION

LAMA2 LAMB1 ERBB2 EGFR

1.91e-04199214M39402
PathwayKEGG_FOCAL_ADHESION

LAMA2 LAMB1 ERBB2 EGFR

1.91e-04199214M7253
PathwayPID_ERBB_NETWORK_PATHWAY

ERBB2 EGFR

2.19e-0415212M201
PathwayREACTOME_ERBB2_REGULATES_CELL_MOTILITY

ERBB2 EGFR

2.19e-0415212M27608
PathwayREACTOME_TFAP2_AP_2_FAMILY_REGULATES_TRANSCRIPTION_OF_GROWTH_FACTORS_AND_THEIR_RECEPTORS

ERBB2 EGFR

2.19e-0415212M27766
PathwayWP_DELTANOTCH_SIGNALING_PATHWAY

EGFR FURIN CCN3

2.34e-0482213MM15922
PathwayREACTOME_CONSTITUTIVE_SIGNALING_BY_ABERRANT_PI3K_IN_CANCER

FGF10 ERBB2 EGFR

2.42e-0483213M27163
PathwayKEGG_MEDICUS_REFERENCE_GF_RTK_PI3K_SIGNALING_PATHWAY

FGF10 ERBB2 EGFR

2.42e-0483213M47961
PathwayREACTOME_GRB2_EVENTS_IN_ERBB2_SIGNALING

ERBB2 EGFR

2.50e-0416212M562
PathwayREACTOME_PI3K_EVENTS_IN_ERBB2_SIGNALING

ERBB2 EGFR

2.50e-0416212M570
PathwayREACTOME_SIGNALING_BY_ERBB2_ECD_MUTANTS

ERBB2 EGFR

2.50e-0416212M29847
PathwayKEGG_MEDICUS_REFERENCE_EGF_ERBB2_RAS_ERK_SIGNALING_PATHWAY

ERBB2 EGFR

2.50e-0416212M47381
PathwayKEGG_ECM_RECEPTOR_INTERACTION

LAMA2 LAMB1 HSPG2

2.51e-0484213M7098
PathwayREACTOME_KERATINIZATION

KRTAP10-1 FURIN KRTAP10-6 KRTAP10-8

2.66e-04217214M27640
PathwayKEGG_MEDICUS_REFERENCE_GF_RTK_RAS_PI3K_SIGNALING_PATHWAY

FGF10 ERBB2 EGFR

2.98e-0489213M47963
PathwayREACTOME_SIGNALING_BY_RECEPTOR_TYROSINE_KINASES

FGF10 ERBB2 MEGF6 EGFR FURIN

3.07e-04418215MM15587
PathwayKEGG_MEDICUS_REFERENCE_GF_RTK_RAS_ERK_SIGNALING_PATHWAY

FGF10 ERBB2 EGFR

3.29e-0492213M47927
PathwayREACTOME_ATTACHMENT_AND_ENTRY

HSPG2 FURIN

3.56e-0419212M41729
PathwayWP_BMP_SIGNALING_PATHWAY_IN_EYELID_DEVELOPMENT

FGF10 EGFR

3.95e-0420212MM15907
PathwayWP_BMP_SIGNALING_IN_EYELID_DEVELOPMENT

FGF10 EGFR

3.95e-0420212M39624
PathwayREACTOME_SHC1_EVENTS_IN_ERBB2_SIGNALING

ERBB2 EGFR

4.80e-0422212M26929
PathwayBIOCARTA_HER2_PATHWAY

ERBB2 EGFR

5.25e-0423212MM1480
PathwayBIOCARTA_HER2_PATHWAY

ERBB2 EGFR

5.25e-0423212M18719
PathwayREACTOME_PI3K_AKT_SIGNALING_IN_CANCER

FGF10 ERBB2 EGFR

5.55e-04110213M27162
PathwayBIOCARTA_TFF_PATHWAY

ERBB2 EGFR

5.72e-0424212M15926
PathwayREACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK

FGF10 ERBB2 EGFR

6.00e-04113213MM14783
PathwayKEGG_MEDICUS_REFERENCE_REGULATION_OF_GF_RTK_RAS_ERK_SIGNALING_UBIQUITINATION_OF_RTK_BY_CBL

ERBB2 EGFR

6.21e-0425212M47934
PathwayWP_SPINAL_CORD_INJURY

SLIT2 PLA2G5 EGFR

6.64e-04117213M39341
PathwayREACTOME_SIGNALING_BY_ERBB2_IN_CANCER

ERBB2 EGFR

6.72e-0426212M29535
PathwayREACTOME_DOWNREGULATION_OF_ERBB2_SIGNALING

ERBB2 EGFR

6.72e-0426212MM15501
PathwayREACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK

FGF10 ERBB2 EGFR

6.81e-04118213M713
PathwayREACTOME_RESPIRATORY_SYNCYTIAL_VIRUS_INFECTION_PATHWAY

HSPG2 EGFR FURIN

7.15e-04120213M48233
PathwayREACTOME_EGR2_AND_SOX10_MEDIATED_INITIATION_OF_SCHWANN_CELL_MYELINATION

LAMA2 LAMB1

8.38e-0429212M29808
PathwayBIOCARTA_TFF_PATHWAY

ERBB2 EGFR

8.38e-0429212MM1522
PathwayREACTOME_DOWNREGULATION_OF_ERBB2_SIGNALING

ERBB2 EGFR

8.38e-0429212M27756
PathwayWP_EXTRACELLULAR_VESICLEMEDIATED_SIGNALING_IN_RECIPIENT_CELLS

ERBB2 EGFR

8.38e-0429212M39516
PathwayREACTOME_MET_ACTIVATES_PTK2_SIGNALING

LAMA2 LAMB1

8.97e-0430212M27772
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

LAMA2 LAMB1 HSPG2 FURIN

9.04e-04300214M610
PathwayWP_FOCAL_ADHESION_PI3KAKTMTORSIGNALING

LAMA2 LAMB1 FGF10 EGFR

9.26e-04302214M39719
PathwayBIOCARTA_AGR_PATHWAY

LAMA2 EGFR

9.58e-0431212MM1343
PathwayWP_MAMMARY_GLAND_DEVELOPMENT_PREGNANCY_AND_LACTATION_STAGE_3_OF_4

ERBB2 EGFR

1.09e-0333212M39455
PathwayWP_ALPHA_6_BETA_4_SIGNALING

LAMA2 LAMB1

1.09e-0333212M39503
PathwayBIOCARTA_AGR_PATHWAY

LAMA2 EGFR

1.09e-0333212M6220
PathwayREACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX

LAMB1 HSPG2 FURIN

1.12e-03140213M587
PathwayWP_FOCAL_ADHESION_PI3KAKTMTOR_SIGNALING_PATHWAY

LAMA2 LAMB1 FGF10 EGFR

1.23e-03326214MM15917
PathwayREACTOME_NERVOUS_SYSTEM_DEVELOPMENT

LAMA2 LAMB1 SLIT2 ERBB2 EGFR

1.31e-03575215M29853
PathwayREACTOME_EARLY_SARS_COV_2_INFECTION_EVENTS

HSPG2 FURIN

1.36e-0337212M45028
PathwayWP_PI3KAKT_SIGNALING

LAMA2 LAMB1 FGF10 EGFR

1.42e-03339214M39736
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_THE_AP_2_TFAP2_FAMILY_OF_TRANSCRIPTION_FACTORS

ERBB2 EGFR

1.44e-0338212M27757
PathwayREACTOME_KERATINIZATION

KRTAP10-1 KRTAP10-6 KRTAP10-8

1.44e-03153213MM15343
PathwayWP_BREAST_CANCER_PATHWAY

FGF10 ERBB2 EGFR

1.47e-03154213M39739
PathwayREACTOME_SIGNALING_BY_NOTCH

EGFR FURIN

1.52e-0339212MM14604
PathwayWP_BLADDER_CANCER

ERBB2 EGFR

1.59e-0340212M39523
PathwayREACTOME_MET_PROMOTES_CELL_MOTILITY

LAMA2 LAMB1

1.67e-0341212M27778
PathwayKEGG_BLADDER_CANCER

ERBB2 EGFR

1.76e-0342212M19096
PathwayREACTOME_SIGNALING_BY_ERBB2

ERBB2 EGFR

1.93e-0344212MM14520
PathwayWP_ERBB_SIGNALING_PATHWAY

ERBB2 EGFR

2.10e-0346212MM15950
PathwayREACTOME_NR1H2_AND_NR1H3_MEDIATED_SIGNALING

KDM4A MYLIP

2.19e-0347212M29777
PathwayREACTOME_SIGNALING_BY_PTK6

ERBB2 EGFR

2.29e-0348212MM15479
PathwayREACTOME_SIGNALING_BY_ERBB2

ERBB2 EGFR

2.48e-0350212M553
PathwayKEGG_ENDOMETRIAL_CANCER

ERBB2 EGFR

2.68e-0352212M19877
PathwayREACTOME_SIGNALING_BY_PTK6

ERBB2 EGFR

2.89e-0354212M29742
PathwayKEGG_NON_SMALL_CELL_LUNG_CANCER

ERBB2 EGFR

2.89e-0354212M19818
PathwayWP_DEVELOPMENT_OF_URETERIC_COLLECTION_SYSTEM

SLIT2 FRAS1

3.55e-0360212M40048
PathwayWP_PLEURAL_MESOTHELIOMA

LAMA2 LAMB1 FGF10 EGFR

3.64e-03439214M42563
PathwayREACTOME_PLASMA_LIPOPROTEIN_ASSEMBLY_REMODELING_AND_CLEARANCE

FURIN MYLIP

3.79e-0362212MM14686
PathwayWP_TAR_SYNDROME

EGFR FURIN

3.91e-0363212M48082
PathwayWP_ENDOMETRIAL_CANCER

ERBB2 EGFR

3.91e-0363212M39623
PathwayWP_PHYSICOCHEMICAL_FEATURES_AND_TOXICITYASSOCIATED_PATHWAYS

ERBB2 EGFR

4.28e-0366212M39642
PathwayPID_INTEGRIN1_PATHWAY

LAMA2 LAMB1

4.28e-0366212M18
PathwayWP_RAC1PAK1P38MMP2_PATHWAY

ERBB2 EGFR

4.54e-0368212M39456
PathwayKEGG_PANCREATIC_CANCER

ERBB2 EGFR

4.80e-0370212M9726
PathwayKEGG_MELANOMA

FGF10 EGFR

4.94e-0371212M15798
PathwayWP_NONSMALL_CELL_LUNG_CANCER

ERBB2 EGFR

5.07e-0372212M39738
PathwayKEGG_ADHERENS_JUNCTION

ERBB2 EGFR

5.21e-0373212M638
PathwayWP_HEAD_AND_NECK_SQUAMOUS_CELL_CARCINOMA

ERBB2 EGFR

5.35e-0374212M39857
PathwayREACTOME_PLASMA_LIPOPROTEIN_ASSEMBLY_REMODELING_AND_CLEARANCE

FURIN MYLIP

5.49e-0375212M27032
PathwayREACTOME_INTRACELLULAR_SIGNALING_BY_SECOND_MESSENGERS

FGF10 ERBB2 EGFR

5.92e-03252213MM15585
PathwayREACTOME_SIGNALING_BY_MET

LAMA2 LAMB1

6.08e-0379212M27643
PathwayWP_CANCER_PATHWAYS

LAMA2 LAMB1 ERBB2 EGFR

6.08e-03507214M48302
Pubmed

Schwann cell myelination requires integration of laminin activities.

LAMA2 LAMB1 HSPG2 ERBB2

2.66e-092130422767514
Pubmed

Basement membrane assembly of the integrin α8β1 ligand nephronectin requires Fraser syndrome-associated proteins.

LAMA2 LAMB1 HSPG2 FRAS1

1.05e-082930422613833
Pubmed

Platelet-derived growth factor receptor regulates salivary gland morphogenesis via fibroblast growth factor expression.

LAMB1 HSPG2 FGF10

2.09e-071430318559345
Pubmed

Basement membrane composition in the early mouse embryo day 7.

LAMA2 LAMB1 HSPG2

2.62e-071530315895400
Pubmed

Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury.

LAMA2 LAMB1 HSPG2 FRAS1

2.76e-076430422261194
Pubmed

A cluster of 21 keratin-associated protein genes within introns of another gene on human chromosome 21q22.3.

KRTAP10-1 KRTAP10-6 KRTAP10-8

3.22e-071630315028290
Pubmed

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.

LAMA2 LAMB1 SLIT2 HSPG2 MEGF6

3.92e-0717530528071719
Pubmed

A direct functional link between the multi-PDZ domain protein GRIP1 and the Fraser syndrome protein Fras1.

LAMA2 LAMB1 FRAS1

4.68e-071830314730302
Pubmed

Transcriptome-based systematic identification of extracellular matrix proteins.

LAMA2 LAMB1 HSPG2 FRAS1

6.46e-077930418757743
Pubmed

Prognostic and predictive values of EGFR overexpression and EGFR copy number alteration in HER2-positive breast cancer.

ERBB2 EGFR

7.19e-07230225349977
Pubmed

Prognostic role of human epidermal growth factor receptor in gastric cancer: a systematic review and meta-analysis.

ERBB2 EGFR

7.19e-07230223871709
Pubmed

HER1 R497K and HER2 I655V polymorphisms are linked to development of breast cancer.

ERBB2 EGFR

7.19e-07230223594562
Pubmed

Identification of autophosphorylation sites of HER2/neu.

ERBB2 EGFR

7.19e-0723021706616
Pubmed

Effects of the combined blockade of EGFR and ErbB-2 on signal transduction and regulation of cell cycle regulatory proteins in breast cancer cells.

ERBB2 EGFR

7.19e-07230219946741
Pubmed

EGFR and ERBB2 Exon 20 Insertion Mutations in Chinese Non-small Cell Lung Cancer Patients: Pathological and Molecular Characterization, and First-Line Systemic Treatment Evaluation.

ERBB2 EGFR

7.19e-07230238416376
Pubmed

Evolutionary analysis of the ErbB receptor and ligand families.

ERBB2 EGFR

7.19e-07230210824084
Pubmed

Genetic and expression analysis of HER-2 and EGFR genes in salivary duct carcinoma: empirical and therapeutic significance.

ERBB2 EGFR

7.19e-07230220371674
Pubmed

Epidermal growth factor receptor status in breast cancer metastases to the central nervous system. Comparison with HER-2/neu status.

ERBB2 EGFR

7.19e-07230215335267
Pubmed

Significance of epidermal growth factor receptor expression in breast cancer.

ERBB2 EGFR

7.19e-07230221104342
Pubmed

Synergistic Blockade of EGFR and HER2 by New-Generation EGFR Tyrosine Kinase Inhibitor Enhances Radiation Effect in Bladder Cancer Cells.

ERBB2 EGFR

7.19e-07230225589492
Pubmed

Protein overexpression and gene amplification of HER-2 and EGFR in colorectal cancers: an immunohistochemical and fluorescent in situ hybridization study.

ERBB2 EGFR

7.19e-07230215143334
Pubmed

An EGFR/HER2-Bispecific and enediyne-energized fusion protein shows high efficacy against esophageal cancer.

ERBB2 EGFR

7.19e-07230224664246
Pubmed

Impact of common epidermal growth factor receptor and HER2 variants on receptor activity and inhibition by lapatinib.

ERBB2 EGFR

7.19e-07230218199554
Pubmed

Status of HER1 and HER2 in peritoneal, ovarian and colorectal endometriosis and ovarian endometrioid adenocarcinoma.

ERBB2 EGFR

7.19e-07230219294416
Pubmed

Expression of erbB-1 and erbB-2 genes in normal and pathological human endometrium.

ERBB2 EGFR

7.19e-07230217549377
Pubmed

Prognostic implications of EGFR and HER-2 alteration assessed by immunohistochemistry and silver in situ hybridization in gastric cancer patients following curative resection.

ERBB2 EGFR

7.19e-07230223955257
Pubmed

The efficient elimination of solid tumor cells by EGFR-specific and HER2-specific scFv-SNAP fusion proteins conjugated to benzylguanine-modified auristatin F.

ERBB2 EGFR

7.19e-07230227502168
Pubmed

Frequent genetic alterations in EGFR- and HER2-driven pathways in breast cancer brain metastases.

ERBB2 EGFR

7.19e-07230223665199
Pubmed

Epidermal growth factor receptor activity is necessary for mouse basal cell proliferation.

ERBB2 EGFR

7.19e-07230225217659
Pubmed

EGFR and HER2 expression in advanced biliary tract cancer.

ERBB2 EGFR

7.19e-07230219777609
Pubmed

Differential cytoskeletal association of ErbB1 and ErbB2 during keratinocyte differentiation.

ERBB2 EGFR

7.19e-07230212135609
Pubmed

Dual inhibition of ErbB1 and ErbB2 in cancer by recombinant human prolidase mutant hPEPD-G278D.

ERBB2 EGFR

7.19e-07230227286447
Pubmed

Increased concentrations of growth factors and activation of the EGFR system in breast cancer.

ERBB2 EGFR

7.19e-07230223089711
Pubmed

EGFR Expression in HER2-Driven Breast Cancer Cells.

ERBB2 EGFR

7.19e-07230233260837
Pubmed

Membrane-bound trafficking regulates nuclear transport of integral epidermal growth factor receptor (EGFR) and ErbB-2.

ERBB2 EGFR

7.19e-07230222451678
Pubmed

The immune microenvironment in EGFR- and ERBB2-mutated lung adenocarcinoma.

ERBB2 EGFR

7.19e-07230234487971
Pubmed

Screening and validation of dinucleotide repeats in intron 1 of the human EGFR gene and its paralog in the HER2 gene.

ERBB2 EGFR

7.19e-07230218946768
Pubmed

Dissecting the molecular recognition of dual lapatinib derivatives for EGFR/HER2.

ERBB2 EGFR

7.19e-07230231828486
Pubmed

Design, biological evaluation and 3D QSAR studies of novel dioxin-containing pyrazoline derivatives with thiourea skeleton as selective HER-2 inhibitors.

ERBB2 EGFR

7.19e-07230227273260
Pubmed

Association of EGFR and HER2 polymorphisms with risk and clinical features of thyroid cancer.

ERBB2 EGFR

7.19e-07230219860576
Pubmed

Androgen receptor controls EGFR and ERBB2 gene expression at different levels in prostate cancer cell lines.

ERBB2 EGFR

7.19e-07230219318561
Pubmed

Induction of cancer cell migration by epidermal growth factor is initiated by specific phosphorylation of tyrosine 1248 of c-erbB-2 receptor via EGFR.

ERBB2 EGFR

7.19e-07230212354693
Pubmed

Fluorescence-Raman dual modal endoscopic system for multiplexed molecular diagnostics.

ERBB2 EGFR

7.19e-07230225820115
Pubmed

HER2 induced EMT and tumorigenicity in breast epithelial progenitor cells is inhibited by coexpression of EGFR.

ERBB2 EGFR

7.19e-07230226686087
Pubmed

Expression of EGFR, Her2 predict lymph node metastasis (LNM)-associated metastasis in colorectal cancer.

ERBB2 EGFR

7.19e-07230223220854
Pubmed

Amplification and expression of EGFR and ERBB2 in Wilms tumor.

ERBB2 EGFR

7.19e-07230219781441
Pubmed

Cardiac ErbB-1/ErbB-2 mutant expression in young adult mice leads to cardiac dysfunction.

ERBB2 EGFR

7.19e-07230218599591
Pubmed

Therapeutic potential of the dual EGFR/HER2 inhibitor AZD8931 in circumventing endocrine resistance.

ERBB2 EGFR

7.19e-07230224554387
Pubmed

Targeting EGFR and HER-2 with cetuximab- and trastuzumab-mediated immunotherapy in oesophageal squamous cell carcinoma.

ERBB2 EGFR

7.19e-07230217622245
Pubmed

Epidermal growth factor receptor, c-erbB2 and c-erbB3 receptor interaction, and related cell cycle kinetics of SK-BR-3 and BT474 breast carcinoma cells.

ERBB2 EGFR

7.19e-07230211500850
Pubmed

Gangliosides influence EGFR/ErbB2 heterodimer stability but they do not modify EGF-dependent ErbB2 phosphorylation.

ERBB2 EGFR

7.19e-07230220156584
Pubmed

EGFR and HER-2 oncogenes expression in an experimental model of two-stage chemically induced carcinogenesis in mouse skin.

ERBB2 EGFR

7.19e-07230238443188
Pubmed

Differential spatial expression and activation pattern of EGFR and HER2 in human breast cancer.

ERBB2 EGFR

7.19e-07230217611648
Pubmed

The correlation between cytoplasmic overexpression of epidermal growth factor receptor and tumor aggressiveness: poor prognosis in patients with pancreatic ductal adenocarcinoma.

ERBB2 EGFR

7.19e-07230215211117
Pubmed

A novel dual EGFR/HER2 inhibitor KU004 induces cell cycle arrest and apoptosis in HER2-overexpressing cancer cells.

ERBB2 EGFR

7.19e-07230226437915
Pubmed

EGFR and HER2 receptor kinase signaling mediate epithelial cell invasion by Candida albicans during oropharyngeal infection.

ERBB2 EGFR

7.19e-07230222891338
Pubmed

Expression of epidermal growth factor receptor and HER-2 in pediatric embryonal brain tumors.

ERBB2 EGFR

7.19e-07230220962551
Pubmed

Structural and energetic basis for the molecular recognition of dual synthetic vs. natural inhibitors of EGFR/HER2.

ERBB2 EGFR

7.19e-07230229329808
Pubmed

Role of epidermal growth factor and ErbB2 receptors in 3T3-L1 adipogenesis.

ERBB2 EGFR

7.19e-07230217372305
Pubmed

Prognostic significance of the co-expression of EGFR and HER2 in adenocarcinoma of the uterine cervix.

ERBB2 EGFR

7.19e-07230228859123
Pubmed

Trastuzumab plus chemotherapy in gastric cancer overexpressing HER-2 and EGFR: a case report.

ERBB2 EGFR

7.19e-07230221346384
Pubmed

Activation of EGFR and ERBB2 by Helicobacter pylori results in survival of gastric epithelial cells with DNA damage.

ERBB2 EGFR

7.19e-07230224530706
Pubmed

Molecular dynamics simulations of asymmetric heterodimers of HER1/HER2 complexes.

ERBB2 EGFR

7.19e-07230229280017
Pubmed

A novel proteotoxic combination therapy for EGFR+ and HER2+ cancers.

ERBB2 EGFR

7.19e-07230230718919
Pubmed

Immunohistochemical correlation of epidermal growth factor receptor and c-erbB-2 with histopathologic grading of mucoepidermoid carcinoma.

ERBB2 EGFR

7.19e-07230223361279
Pubmed

Dual-Receptor-Targeted (DRT) Radiation Nanomedicine Labeled with 177Lu Is More Potent for Killing Human Breast Cancer Cells That Coexpress HER2 and EGFR Than Single-Receptor-Targeted (SRT) Radiation Nanomedicines.

ERBB2 EGFR

7.19e-07230232022567
Pubmed

Comparative analysis of fluorescence resonance energy transfer (FRET) and proximity ligation assay (PLA).

ERBB2 EGFR

7.19e-07230221480528
Pubmed

Targeting EGFR/HER2 pathways enhances the antiproliferative effect of gemcitabine in biliary tract and gallbladder carcinomas.

ERBB2 EGFR

7.19e-07230221087480
Pubmed

A Comparison of Immunohistochemical Expression of Epidermal Growth Factor Receptor and Human Epidermal Growth Factor Receptor 2 in Dental Follicles with Different Radiographic Sizes.

ERBB2 EGFR

7.19e-07230239205824
Pubmed

ErbB receptor-driven prolactinomas respond to targeted lapatinib treatment in female transgenic mice.

ERBB2 EGFR

7.19e-07230225375038
Pubmed

Lapatinib, a dual inhibitor of ErbB-1/-2 receptors, enhances effects of combination chemotherapy in bladder cancer cells.

ERBB2 EGFR

7.19e-07230219287975
Pubmed

The signaling and transformation potency of the overexpressed HER2 protein is dependent on the normally-expressed EGFR.

ERBB2 EGFR

7.19e-07230221911055
Pubmed

Pre-diagnostic serum levels of EGFR and ErbB2 and genetic glioma risk variants: a nested case-control study.

ERBB2 EGFR

7.19e-07230226906551
Pubmed

Cross-reactivity of EGFR mutation-specific immunohistochemistry assay in HER2-positive tumors.

ERBB2 EGFR

7.19e-07230225390349
Pubmed

Differential c-erbB-1 and c-erbB-2 mRNA expression in cancer of the pancreas compared with cancer of the papilla of Vater.

ERBB2 EGFR

7.19e-07230216489645
Pubmed

Elevated levels of epidermal growth factor receptor/c-erbB2 heterodimers mediate an autocrine growth regulatory pathway in tamoxifen-resistant MCF-7 cells.

ERBB2 EGFR

7.19e-07230212586780
Pubmed

Overexpression of Epidermal Growth Factor Receptor (EGFR) and HER-2 in Bladder Carcinoma and Its Association with Patients' Clinical Features.

ERBB2 EGFR

7.19e-07230230296252
Pubmed

EGFR and ERBB2 Germline Mutations in Chinese Lung Cancer Patients and Their Roles in Genetic Susceptibility to Cancer.

ERBB2 EGFR

7.19e-07230230610926
Pubmed

Multiple ErbB-2/Neu Phosphorylation Sites Mediate Transformation through Distinct Effector Proteins.

ERBB2 EGFR

7.19e-07230211500516
Pubmed

EGFR negates the proliferative effect of oncogenic HER2 in MDA-MB-231 cells.

ERBB2 EGFR

7.19e-07230225935365
Pubmed

Flow cytometric in situ proximity ligation analyses of protein interactions and post-translational modification of the epidermal growth factor receptor family.

ERBB2 EGFR

7.19e-07230219650109
Pubmed

[Relationship between HER2/neu gene amplification and protein expression and prognosis in patients with advanced gastric carcinoma].

ERBB2 EGFR

7.19e-07230220038314
Pubmed

The Dipole Potential Modifies the Clustering and Ligand Binding Affinity of ErbB Proteins and Their Signaling Efficiency.

ERBB2 EGFR

7.19e-07230227775011
Pubmed

Antitumor and antiangiogenic effect of the dual EGFR and HER-2 tyrosine kinase inhibitor lapatinib in a lung cancer model.

ERBB2 EGFR

7.19e-07230220459769
Pubmed

Serum levels of epidermal growth factor and HER-2 neu in non small-cell lung cancer: prognostic correlation.

ERBB2 EGFR

7.19e-07230219093231
Pubmed

Circular HER2 RNA positive triple negative breast cancer is sensitive to Pertuzumab.

ERBB2 EGFR

7.19e-07230232917240
Pubmed

EGFR and erbB2 in malignant peripheral nerve sheath tumors and implications for targeted therapy.

ERBB2 EGFR

7.19e-07230218650488
Pubmed

Genomic activation of the EGFR and HER2-neu genes in a significant proportion of invasive epithelial ovarian cancers.

ERBB2 EGFR

7.19e-07230218182111
Pubmed

Expression of herstatin, an autoinhibitor of HER-2/neu, inhibits transactivation of HER-3 by HER-2 and blocks EGF activation of the EGF receptor.

ERBB2 EGFR

7.19e-07230211526509
Pubmed

A role of Rab7 in stabilizing EGFR-Her2 and in sustaining Akt survival signal.

ERBB2 EGFR

7.19e-07230221928319
Pubmed

Correlations of EGFR mutations and increases in EGFR and HER2 copy number to gefitinib response in a retrospective analysis of lung cancer patients.

ERBB2 EGFR

7.19e-07230217626639
Pubmed

Affinity-Tuned ErbB2 or EGFR Chimeric Antigen Receptor T Cells Exhibit an Increased Therapeutic Index against Tumors in Mice.

ERBB2 EGFR

7.19e-07230226330166
Pubmed

EGFR and HER2 signals play a salvage role in MEK1-mutated gastric cancer after MEK inhibition.

ERBB2 EGFR

7.19e-07230226081723
Pubmed

Overexpression of c-erbB-2 oncoprotein and associated pathobiological factors in invasive primary breast cancer.

ERBB2 EGFR

7.19e-07230215233293
Pubmed

Critical roles for EGFR and EGFR-HER2 clusters in EGF binding of SW620 human carcinoma cells.

ERBB2 EGFR

7.19e-07230235612280
Pubmed

The Transmodulation of HER2 and EGFR by Substance P in Breast Cancer Cells Requires c-Src and Metalloproteinase Activation.

ERBB2 EGFR

7.19e-07230226114632
Pubmed

Capsaicin causes cell-cycle arrest and apoptosis in ER-positive and -negative breast cancer cells by modulating the EGFR/HER-2 pathway.

ERBB2 EGFR

7.19e-07230219855437
Pubmed

Assessment of HER1 (rs11543848) and HER2 (rs1136201) polymorphism and their association with colorectal cancer susceptibility in Khyber Pakhtunkhwa, Pakistan.

ERBB2 EGFR

7.19e-07230238040921
Pubmed

HER2 and EGFR amplification and expression in urothelial carcinoma occurs in distinct biological and molecular contexts.

ERBB2 EGFR

7.19e-07230228388586
Pubmed

EGFR and erbB2 mutation status in Japanese lung cancer patients.

ERBB2 EGFR

7.19e-07230216003726
InteractionSPATA3 interactions

SPATA3 VWC2L KRTAP10-1 KRTAP10-6 KRTAP10-8

1.48e-1024285int:SPATA3
InteractionLCE3D interactions

VWC2L KRTAP10-1 KRTAP10-6 CCN3 KRTAP10-8

5.00e-0873285int:LCE3D
InteractionLCE1A interactions

VWC2L KRTAP10-1 KRTAP10-6 CCN3 KRTAP10-8

1.02e-0784285int:LCE1A
InteractionHOXA1 interactions

VWC2L SLIT2 MEGF6 MEGF8 KRTAP10-1 CCN3 KRTAP10-8

4.35e-07356287int:HOXA1
InteractionC17orf50 interactions

VWC2L KRTAP10-1 KRTAP10-8

5.24e-0712283int:C17orf50
InteractionCRCT1 interactions

VWC2L EGFR KRTAP10-1 KRTAP10-8

2.02e-0666284int:CRCT1
InteractionZNF138 interactions

KRTAP10-1 KRTAP10-6 KRTAP10-8

2.29e-0619283int:ZNF138
InteractionNKD1 interactions

KRTAP10-1 KRTAP10-6 KRTAP10-8

3.14e-0621283int:NKD1
InteractionKRTAP4-5 interactions

KRTAP10-1 KRTAP10-6 KRTAP10-8 PEAR1

3.57e-0676284int:KRTAP4-5
InteractionMOBP interactions

KRTAP10-1 KRTAP10-6 KRTAP10-8

4.18e-0623283int:MOBP
InteractionSDF2L1 interactions

LAMB1 HSPG2 FRAS1 MEGF8 EGFR SUSD2

4.45e-06322286int:SDF2L1
InteractionZNF319 interactions

EGFR KRTAP10-6 KRTAP10-8

6.87e-0627283int:ZNF319
InteractionLCE5A interactions

VWC2L KRTAP10-1 KRTAP10-6 KRTAP10-8

7.01e-0690284int:LCE5A
InteractionKRTAP5-6 interactions

KRTAP10-1 KRTAP10-6 CCN3 KRTAP10-8

8.34e-0694284int:KRTAP5-6
InteractionDEFB112 interactions

VWC2L KRTAP10-1

1.11e-054282int:DEFB112
InteractionPDGFA interactions

LAMB1 HSPG2 FURIN

1.16e-0532283int:PDGFA
InteractionPRELP interactions

HSPG2 FRAS1 MEGF8

1.16e-0532283int:PRELP
InteractionFBXO2 interactions

LAMB1 SLIT2 HSPG2 FRAS1 MEGF8 EGFR

1.79e-05411286int:FBXO2
InteractionVWC2L interactions

SPATA3 VWC2L KRTAP10-8

2.29e-0540283int:VWC2L
InteractionCCN2 interactions

HSPG2 EGFR CCN3

2.29e-0540283int:CCN2
InteractionZNF440 interactions

KRTAP10-1 KRTAP10-6 KRTAP10-8

2.29e-0540283int:ZNF440
InteractionCACNA1A interactions

LAMB1 HSPG2 MEGF6 MEGF8

2.42e-05123284int:CACNA1A
InteractionPSG8 interactions

LAMB1 FRAS1 MEGF8

2.47e-0541283int:PSG8
InteractionZNF264 interactions

KRTAP10-1 KRTAP10-6 KRTAP10-8

2.47e-0541283int:ZNF264
InteractionIL5RA interactions

HSPG2 FRAS1 MEGF8 EGFR

2.49e-05124284int:IL5RA
InteractionITGB4 interactions

LAMB1 ERBB2 EGFR KRTAP10-8

2.57e-05125284int:ITGB4
InteractionKRTAP4-2 interactions

SPATA3 KRTAP10-1 KRTAP10-6 KRTAP10-8

3.19e-05132284int:KRTAP4-2
InteractionLCE3B interactions

KRTAP10-1 KRTAP10-6 KRTAP10-8

3.50e-0546283int:LCE3B
InteractionGFI1B interactions

LAMB1 HSPG2 MEGF6 MEGF8

3.58e-05136284int:GFI1B
InteractionAVPI1 interactions

KRTAP10-1 KRTAP10-6 KRTAP10-8

3.98e-0548283int:AVPI1
InteractionC22orf39 interactions

VWC2L KRTAP10-1 KRTAP10-8

4.24e-0549283int:C22orf39
InteractionKRTAP10-1 interactions

SPATA3 KRTAP10-1 KRTAP10-6 KRTAP10-8

5.67e-05153284int:KRTAP10-1
InteractionFBXO34 interactions

VWC2L KRTAP10-1 KRTAP10-8

6.00e-0555283int:FBXO34
InteractionMUC4 interactions

ERBB2 EGFR

6.66e-059282int:MUC4
InteractionTYRO3 interactions

VWC2L NFXL1 ERBB2 KRTAP10-8

6.75e-05160284int:TYRO3
InteractionKRTAP10-5 interactions

SPATA3 KRTAP10-1 KRTAP10-6 KRTAP10-8

6.75e-05160284int:KRTAP10-5
InteractionWDR25 interactions

LAMB1 FRAS1 EGFR

7.04e-0558283int:WDR25
InteractionLYPD1 interactions

LAMB1 FRAS1 MEGF8

7.04e-0558283int:LYPD1
InteractionLCE3E interactions

KRTAP10-1 KRTAP10-6 KRTAP10-8

7.79e-0560283int:LCE3E
InteractionCOL9A3 interactions

ERBB2 EGFR

8.32e-0510282int:COL9A3
InteractionKRTAP5-2 interactions

KRTAP10-1 KRTAP10-6 KRTAP10-8

8.60e-0562283int:KRTAP5-2
InteractionKRTAP5-4 interactions

KRTAP10-1 KRTAP10-6 KRTAP10-8

9.02e-0563283int:KRTAP5-4
InteractionKRTAP10-11 interactions

SPATA3 KRTAP10-1 KRTAP10-8

9.45e-0564283int:KRTAP10-11
InteractionNPDC1 interactions

KRTAP10-1 KRTAP10-6 KRTAP10-8

9.90e-0565283int:NPDC1
InteractionPTPRK interactions

LAMB1 FRAS1 MEGF8 EGFR

9.99e-05177284int:PTPRK
InteractionPTPRT interactions

ERBB2 EGFR

1.02e-0411282int:PTPRT
InteractionPOM121L8P interactions

KRTAP10-1 KRTAP10-8

1.02e-0411282int:POM121L8P
InteractionKRTAP5-11 interactions

KRTAP10-1 KRTAP10-6 KRTAP10-8

1.04e-0466283int:KRTAP5-11
InteractionKRTAP5-3 interactions

KRTAP10-1 KRTAP10-6 KRTAP10-8

1.04e-0466283int:KRTAP5-3
InteractionLCE3C interactions

KRTAP10-1 KRTAP10-6 KRTAP10-8

1.08e-0467283int:LCE3C
InteractionNR1D2 interactions

KRTAP10-1 KRTAP10-8 MYLIP

1.08e-0467283int:NR1D2
InteractionLCE1E interactions

KRTAP10-1 KRTAP10-6 KRTAP10-8

1.13e-0468283int:LCE1E
InteractionNR4A3 interactions

VWC2L KRTAP10-1 KRTAP10-8

1.18e-0469283int:NR4A3
InteractionLCE2A interactions

KRTAP10-1 KRTAP10-6 KRTAP10-8

1.18e-0469283int:LCE2A
InteractionLCE1D interactions

KRTAP10-1 KRTAP10-6 KRTAP10-8

1.24e-0470283int:LCE1D
InteractionNAXD interactions

NFXL1 KRTAP10-6 KRTAP10-8

1.29e-0471283int:NAXD
InteractionZNF559 interactions

KRTAP10-1 KRTAP10-8

1.44e-0413282int:ZNF559
InteractionLCE2D interactions

KRTAP10-1 KRTAP10-6 KRTAP10-8

1.46e-0474283int:LCE2D
InteractionWT1 interactions

KRTAP10-1 KRTAP10-6 KRTAP10-8

1.58e-0476283int:WT1
InteractionLCE3A interactions

VWC2L KRTAP10-1 KRTAP10-8

1.58e-0476283int:LCE3A
InteractionLCE1C interactions

VWC2L KRTAP10-1 KRTAP10-8

1.64e-0477283int:LCE1C
InteractionPIN1 interactions

ERBB2 DEAF1 KRTAP10-1 KRTAP10-6 KRTAP10-8

1.66e-04383285int:PIN1
InteractionPRR19 interactions

EGFR KRTAP10-8

1.68e-0414282int:PRR19
InteractionROBO4 interactions

SLIT2 EGFR

1.68e-0414282int:ROBO4
InteractionKRTAP5-9 interactions

SPATA3 KRTAP10-1 KRTAP10-6 KRTAP10-8

1.69e-04203284int:KRTAP5-9
InteractionLCE4A interactions

KRTAP10-1 KRTAP10-6 KRTAP10-8

1.84e-0480283int:LCE4A
InteractionKRTAP4-4 interactions

KRTAP10-1 KRTAP10-6 KRTAP10-8

1.91e-0481283int:KRTAP4-4
InteractionLCE2B interactions

KRTAP10-1 KRTAP10-6 KRTAP10-8

1.91e-0481283int:LCE2B
InteractionADAMTSL3 interactions

KRTAP10-6 KRTAP10-8

1.93e-0415282int:ADAMTSL3
InteractionAPOL6 interactions

CCN3 KRTAP10-8

1.93e-0415282int:APOL6
InteractionZNF625 interactions

KRTAP10-1 KRTAP10-8

1.93e-0415282int:ZNF625
InteractionPOU4F2 interactions

KRTAP10-1 CCN3 KRTAP10-8

2.05e-0483283int:POU4F2
InteractionKRTAP10-8 interactions

SPATA3 VWC2L KRTAP10-1 SUSD2 KRTAP10-8

2.05e-04401285int:KRTAP10-8
InteractionPTPRH interactions

ERBB2 EGFR KRTAP10-8

2.12e-0484283int:PTPRH
InteractionLCE1B interactions

KRTAP10-1 KRTAP10-6 KRTAP10-8

2.20e-0485283int:LCE1B
InteractionKRTAP4-7 interactions

EGFR KRTAP10-8

2.21e-0416282int:KRTAP4-7
InteractionMEGF6 interactions

MEGF6 EGFR

2.21e-0416282int:MEGF6
InteractionSUSD2 interactions

SUSD2 KRTAP10-8

2.21e-0416282int:SUSD2
InteractionAREG interactions

EGFR KRTAP10-8

2.21e-0416282int:AREG
InteractionCEND1 interactions

ERBB2 EGFR

2.21e-0416282int:CEND1
InteractionNID2 interactions

LAMB1 HSPG2 CCN3

2.28e-0486283int:NID2
InteractionSIRPD interactions

HSPG2 FRAS1 MEGF8

2.28e-0486283int:SIRPD
InteractionLCE2C interactions

KRTAP10-1 KRTAP10-6 KRTAP10-8

2.44e-0488283int:LCE2C
InteractionKRTAP10-6 interactions

SPATA3 KRTAP10-1 KRTAP10-6

2.44e-0488283int:KRTAP10-6
InteractionCAMK1G interactions

KRTAP10-1 KRTAP10-8

2.50e-0417282int:CAMK1G
InteractionRNF8 interactions

NFXL1 KDM4A EGFR KRTAP10-1 KRTAP10-8

2.57e-04421285int:RNF8
InteractionLCE1F interactions

KRTAP10-1 KRTAP10-6 KRTAP10-8

2.78e-0492283int:LCE1F
InteractionKRTAP4-11 interactions

KRTAP10-1 KRTAP10-6 KRTAP10-8

2.78e-0492283int:KRTAP4-11
InteractionZAP70 interactions

ERBB2 EGFR PEAR1

2.78e-0492283int:ZAP70
InteractionSHD interactions

ERBB2 EGFR

2.81e-0418282int:SHD
InteractionMPZL2 interactions

ERBB2 EGFR

2.81e-0418282int:MPZL2
InteractionTNS2 interactions

ERBB2 EGFR SUSD2 KRTAP10-8

2.96e-04235284int:TNS2
InteractionADAMTS1 interactions

EGFR FURIN KRTAP10-8

3.05e-0495283int:ADAMTS1
InteractionSHFL interactions

EGFR KRTAP10-1 KRTAP10-8

3.24e-0497283int:SHFL
InteractionKRTAP10-9 interactions

SPATA3 EGFR KRTAP10-1 KRTAP10-8

3.26e-04241284int:KRTAP10-9
InteractionGGH interactions

LAMB1 FRAS1 MEGF8 EGFR

3.36e-04243284int:GGH
InteractionZNF114 interactions

EGFR KRTAP10-6

3.48e-0420282int:ZNF114
InteractionKRTAP9-8 interactions

KRTAP10-1 KRTAP10-6 KRTAP10-8

3.55e-04100283int:KRTAP9-8
InteractionDEFA1 interactions

LAMB1 SLIT2 EGFR

3.55e-04100283int:DEFA1
InteractionFBXO6 interactions

LAMB1 HSPG2 FRAS1 MUC5B MEGF8 EGFR

3.83e-04717286int:FBXO6
Cytoband21q22.3

KRTAP10-1 KRTAP10-6 KRTAP10-8

8.13e-0512830321q22.3
CytobandEnsembl 112 genes in cytogenetic band chr21q22

KRTAP10-1 KRTAP10-6 KRTAP10-8

1.89e-03377303chr21q22
Cytoband11p15.5

MUC5B DEAF1

2.72e-0311830211p15.5
CytobandEnsembl 112 genes in cytogenetic band chr1p36

PLA2G5 HSPG2 MEGF6

9.80e-03681303chr1p36
GeneFamilyKeratin associated proteins

KRTAP4-16 KRTAP10-1 KRTAP10-6 KRTAP10-8

3.58e-06109184619
GeneFamilyErb-b2 receptor tyrosine kinases

ERBB2 EGFR

5.61e-0641821096
GeneFamilyLaminin subunits

LAMA2 LAMB1

6.14e-0512182626
CoexpressionNABA_MATRISOME

VWC2L BRINP2 LAMA2 KCP LAMB1 SLIT2 HSPG2 FGF10 FRAS1 MUC5B MEGF6 MEGF8 CCN3

8.17e-1210082813MM17056
CoexpressionNABA_MATRISOME

VWC2L BRINP2 LAMA2 KCP LAMB1 SLIT2 HSPG2 FGF10 FRAS1 MUC5B MEGF6 MEGF8 CCN3

1.02e-1110262813M5889
CoexpressionNABA_CORE_MATRISOME

LAMA2 KCP LAMB1 SLIT2 HSPG2 FRAS1 CCN3

1.12e-08270287MM17057
CoexpressionNABA_CORE_MATRISOME

LAMA2 KCP LAMB1 SLIT2 HSPG2 FRAS1 CCN3

1.27e-08275287M5884
CoexpressionNABA_ECM_GLYCOPROTEINS

LAMA2 KCP LAMB1 SLIT2 FRAS1 CCN3

4.56e-08191286MM17059
CoexpressionNABA_ECM_GLYCOPROTEINS

LAMA2 KCP LAMB1 SLIT2 FRAS1 CCN3

5.32e-08196286M3008
CoexpressionHEVNER_TELENCEPHALON_VASCULAR_ENDOTHELIUM_AND_MENINGEAL_CELLS

LAMB1 HSPG2 MYLIP

4.92e-0715283MM402
CoexpressionHE_LIM_SUN_FETAL_LUNG_C7_MID_SCHWANN_CELL

LAMA2 LAMB1 SLIT2 HSPG2 ERBB2

8.73e-06268285M45796
CoexpressionNABA_BASEMENT_MEMBRANES

LAMA2 LAMB1 HSPG2

1.05e-0540283M5887
CoexpressionPAPASPYRIDONOS_UNSTABLE_ATEROSCLEROTIC_PLAQUE_DN

EGFR CCN3 MYLIP

1.31e-0543283M12432
CoexpressionNABA_SECRETED_FACTORS

VWC2L BRINP2 FGF10 MEGF6 MEGF8

2.67e-05338285MM17064
CoexpressionYAMAZAKI_TCEB3_TARGETS_UP

LAMB1 HSPG2 SUSD2 FURIN

2.82e-05166284M1542
CoexpressionNABA_SECRETED_FACTORS

VWC2L BRINP2 FGF10 MEGF6 MEGF8

2.86e-05343285M5883
CoexpressionTCGA_GLIOBLASTOMA_MUTATED

ERBB2 EGFR

3.07e-058282M19387
CoexpressionYAMAZAKI_TCEB3_TARGETS_UP

LAMB1 HSPG2 SUSD2 FURIN

3.79e-05179284MM660
CoexpressionPEREZ_TP53_AND_TP63_TARGETS

SLIT2 MEGF6 SUSD2 MYLIP

6.67e-05207284M14566
CoexpressionFRASOR_RESPONSE_TO_ESTRADIOL_DN

LAMB1 SLIT2 ERBB2

7.87e-0578283M3002
CoexpressionNABA_MATRISOME_ASSOCIATED

VWC2L BRINP2 FGF10 MUC5B MEGF6 MEGF8

1.08e-04738286MM17058
CoexpressionBREUHAHN_GROWTH_FACTOR_SIGNALING_IN_LIVER_CANCER

ERBB2 EGFR

1.15e-0415282M18219
CoexpressionNABA_MATRISOME_ASSOCIATED

VWC2L BRINP2 FGF10 MUC5B MEGF6 MEGF8

1.19e-04751286M5885
CoexpressionCHIBA_RESPONSE_TO_TSA_DN

LAMB1 EGFR

2.28e-0421282M12459
CoexpressionPLASARI_NFIC_TARGETS_BASAL_DN

SLIT2 CCN3

2.51e-0422282M2449
CoexpressionPLASARI_NFIC_TARGETS_BASAL_DN

SLIT2 CCN3

2.75e-0423282MM945
CoexpressionGSE12839_CTRL_VS_IL12_TREATED_PBMC_DN

SPATA3 MEGF6 MYLIP

3.33e-04127283M441
CoexpressionGSE37532_VISCERAL_ADIPOSE_TISSUE_VS_LN_DERIVED_PPARG_KO_TREG_CD4_TCELL_DN

BRINP2 FURIN PEAR1

4.34e-04139283M8948
CoexpressionTHEODOROU_MAMMARY_TUMORIGENESIS

LAMB1 FGF10

5.02e-0431282M1291
CoexpressionPEREZ_TP63_TARGETS

SLIT2 MEGF6 SUSD2 MYLIP

5.29e-04356284M10761
CoexpressionDESCARTES_FETAL_LIVER_STELLATE_CELLS

LAMA2 LAMB1 FGF10

6.54e-04160283M40233
CoexpressionVERHAAK_GLIOBLASTOMA_CLASSICAL

PLA2G5 MEGF8 EGFR

6.66e-04161283M2121
CoexpressionHU_FETAL_RETINA_FIBROBLAST

LAMB1 EGFR MYLIP PEAR1

7.10e-04385284M39264
CoexpressionTHEODOROU_MAMMARY_TUMORIGENESIS

LAMB1 FGF10

7.16e-0437282MM1121
CoexpressionHE_LIM_SUN_FETAL_LUNG_C7_PROLIFERATING_SCHWANN_CELL

LAMA2 SLIT2 HSPG2 ERBB2 MEGF8 CCN3

7.34e-041054286M45798
CoexpressionLAKE_ADULT_KIDNEY_C15_CONNECTING_TUBULE

LAMB1 SLIT2 FRAS1

7.93e-04171283M39234
CoexpressionGAZDA_DIAMOND_BLACKFAN_ANEMIA_MYELOID_DN

CCN3 MYLIP

8.79e-0441282M6979
CoexpressionVECCHI_GASTRIC_CANCER_ADVANCED_VS_EARLY_UP

LAMA2 SLIT2 IER5L

8.90e-04178283M17079
CoexpressionDAVICIONI_MOLECULAR_ARMS_VS_ERMS_DN

LAMA2 ERBB2 EGFR

9.05e-04179283M8519
CoexpressionAtlasStromal Cells, Fi.Sk, gp38+ CD140a+, Skin, avg-4

LAMA2 LAMB1 SLIT2 HSPG2 EGFR CCN3

1.51e-05437276GSM777046_500
CoexpressionAtlasStromal Cells, Fi.MTS15+.Th, CD45- PDGFRa+ MTS15+, Thymus, avg-3

LAMA2 LAMB1 SLIT2 HSPG2 EGFR SUSD2

1.67e-05445276GSM777043_500
CoexpressionAtlasStromal Cells, St.31-38-44-.SLN, CD45- gp38- CD31- CD44-, Lymph Node, avg-2

LAMA2 LAMB1 HSPG2 EGFR SUSD2 CCN3

1.85e-05453276GSM777067_500
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_k-means-cluster#3_top-relative-expression-ranked_200

LAMA2 SLIT2 EGFR

1.52e-0482273gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_k3_200
CoexpressionAtlasStromal Cells, LEC.MLN, gp38+ CD31+, Lymph Node, avg-4

LAMB1 SLIT2 HSPG2 SUSD2 PEAR1

2.05e-04439275GSM777059_500
CoexpressionAtlasStromal Cells, Fi.MTS15+.Th, CD45- PDGFRa+ MTS15+, Thymus, avg-3

LAMA2 LAMB1 HSPG2

2.50e-0497273GSM777043_100
CoexpressionAtlasdev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_1000

LAMA2 LAMB1 SLIT2 PLA2G5 FGF10 EGFR

3.39e-04768276gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_1000
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPATA3 LAMA2 KCP FGF10 FRAS1 MUC5B

1.02e-09160306c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPATA3 LAMA2 KCP FGF10 FRAS1 MUC5B

1.02e-0916030625c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellRV-01._Fibroblast_I|World / Chamber and Cluster_Paper

LAMA2 LAMB1 SLIT2 PLA2G5 FGF10 EGFR

2.95e-0919130670c067c54084bfb02c29bab085f4defd477194fb
ToppCellRV-01._Fibroblast_I|RV / Chamber and Cluster_Paper

LAMA2 LAMB1 SLIT2 PLA2G5 FGF10 EGFR

3.04e-09192306356160b113c3305a61ceeaff33ce3c9da0be2878
ToppCellRV-02._Fibroblast_II|RV / Chamber and Cluster_Paper

LAMA2 LAMB1 SLIT2 PLA2G5 FGF10 EGFR

3.24e-0919430611c79a8c56ece42713b04b321982e41e239f07a5
ToppCellRV-02._Fibroblast_II|World / Chamber and Cluster_Paper

LAMA2 LAMB1 SLIT2 PLA2G5 FGF10 EGFR

3.34e-09195306ce90b30dcdb56d4cd925cdb79fd9d7cefd998f48
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HSPG2 ERBB2 FRAS1 EGFR SUSD2

1.31e-07181305b45b11428d13950369347e051d4d517efb2bd4fd
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HSPG2 ERBB2 FRAS1 EGFR SUSD2

1.50e-071863053aebe163799109ffc67e4e10ee47c2dd0886a92c
ToppCellCOVID-19-Heart-Fib_1|COVID-19 / Disease (COVID-19 only), tissue and cell type

LAMA2 LAMB1 SLIT2 PLA2G5 EGFR

1.58e-07188305fe361215f4ba841aa5e1e581fb56f2f4d3ccd201
ToppCellLV-01._Fibroblast_I|World / Chamber and Cluster_Paper

LAMA2 LAMB1 SLIT2 PLA2G5 EGFR

1.67e-0719030512992ec80a7b4f4f17de693f0719ee061a9918fd
ToppCellLV-02._Fibroblast_II|World / Chamber and Cluster_Paper

LAMA2 LAMB1 SLIT2 PLA2G5 EGFR

1.71e-07191305d36565257ccba8c1bbed2c1c01be66a9cbb5f834
ToppCellfacs-Heart-LV-3m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA2 KCP LAMB1 EGFR SUSD2

1.71e-07191305b7a57691a4742070cee640e285c1f4d0da95baf1
ToppCellCOVID-19-Heart-Fib_+_EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

LAMA2 LAMB1 SLIT2 PLA2G5 EGFR

1.76e-0719230560b1312e84f6d6448365a952469c506c00b5fe93
ToppCellfacs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA2 KCP LAMB1 HSPG2 EGFR

1.76e-07192305671d4e1eee5aba03c43dbc98f4b51ce42b3df5d5
ToppCellfacs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA2 KCP LAMB1 HSPG2 EGFR

1.76e-07192305840a34c1b82d218be999ab5e1bcafd6370d7a4b1
ToppCellLV-01._Fibroblast_I|LV / Chamber and Cluster_Paper

LAMA2 LAMB1 SLIT2 PLA2G5 EGFR

1.80e-07193305dc17f3b9758936d428cf17f77a1ce6d4c479b165
ToppCellMesenchymal-matrix_fibroblast_1_cell|World / Lineage, Cell type, age group and donor

LAMA2 LAMB1 SLIT2 FGF10 FRAS1

1.80e-07193305acad568621ed677031797b8c2e34dafea798d681
ToppCellLV-02._Fibroblast_II|LV / Chamber and Cluster_Paper

LAMA2 LAMB1 SLIT2 PLA2G5 EGFR

1.85e-07194305014d2feb5db2a6a35ef759761a41e466e108c3c1
ToppCellCOVID-19-Fibroblasts-Alveolar_FB|COVID-19 / group, cell type (main and fine annotations)

LAMA2 LAMB1 SLIT2 FGF10 FRAS1

1.90e-07195305603050beeb33c331d4b2e3fa46cae3f3e0e4bdc7
ToppCellCOVID-19-Heart-Fib_1|Heart / Disease (COVID-19 only), tissue and cell type

LAMA2 LAMB1 SLIT2 PLA2G5 EGFR

1.90e-07195305f423baa36ac7cdc383c033e35a7d17e6bf913323
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-mesenchymal|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

LAMA2 LAMB1 HSPG2 FGF10 EGFR

1.99e-0719730517344464fdcc5ba0c03959696b97c195f11e644c
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-mesenchymal-mesenchymal-mesenchymal_stem_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

LAMA2 LAMB1 HSPG2 FGF10 EGFR

1.99e-071973053bb92dd8a94e2be3b7fe51c9a21b241215477ac7
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-mesenchymal-mesenchymal|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

LAMA2 LAMB1 HSPG2 FGF10 EGFR

1.99e-071973055b8d0d7116b20d8e27541e88ec80c9f1f477e384
ToppCellFibroblasts-HLA-DRA_high_Fibroblasts|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

LAMB1 SLIT2 HSPG2 FGF10 EGFR

2.04e-07198305e8c0fbf306fae13e97caa294d7c99a564bd97130
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Pericyte|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

LAMA2 KCP LAMB1 SLIT2 CCN3

2.15e-07200305b5b5a32925f225610fe25a021a742d6397162863
ToppCellAdult-Mesenchymal-myofibroblast_cell|Adult / Lineage, Cell type, age group and donor

BRINP2 LAMA2 SLIT2 FGF10

4.65e-06167304d584a8548a5317bd9686b3be8246ae6ed568796b
ToppCellRA-01._Fibroblast_I|RA / Chamber and Cluster_Paper

LAMA2 LAMB1 SLIT2 PLA2G5

4.88e-061693046373562ab3b1765060212a6a53d6543e7e942e80
ToppCellNS-critical-d_0-4-Epithelial-Secretory|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

HSPG2 ERBB2 MUC5B EGFR

4.88e-06169304aec97583b23112060437b619cb429dc32f29285f
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Macroglial-astrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPATA3 SLIT2 PLA2G5 EGFR

5.23e-06172304e15ab284df6dd241d4481f98864b18c39d757b8c
ToppCell5'-Adult-LargeIntestine-Mesenchymal-stromal_related|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAMA2 PLA2G5 FGF10 MEGF6

5.60e-06175304b8995e7ada85ba959f06264a0295b61e390c4e6c
ToppCell5'-Adult-LargeIntestine-Mesenchymal-stromal_related-T_reticular|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAMA2 PLA2G5 FGF10 MEGF6

5.60e-061753047ae76bd3b4f610b2f98716a4456437cd3696b686
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage_3|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

LAMB1 PLA2G5 HSPG2 EGFR

5.86e-061773043d955ea938a1d2fb1b6d68d4997fd454bd632dfc
ToppCell368C-Myeloid-Macrophage-SPP1+_Macrophage_3|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

KCP MEGF6 IER5L MYLIP

5.86e-06177304eb0cfe8e9a91910f9979608ed47add48d98ce4dd
ToppCellLA-01._Fibroblast_I|LA / Chamber and Cluster_Paper

LAMA2 SLIT2 PLA2G5 EGFR

6.12e-06179304dcb6ec9ae72b13fe388b72dace2815293fafe8ee
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

LAMA2 LAMB1 SLIT2 FRAS1

6.40e-061813049ede19228ba5c0668a9c06c915510b95585216ef
ToppCellCOVID-19-Heart-Fib_+_EC_+_Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

LAMA2 LAMB1 PLA2G5 HSPG2

6.54e-06182304fbd5e332df73bf7141c822fa67b76367dc962017
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LAMA2 KCP LAMB1 SLIT2

6.68e-061833048a799807fbf24456a9811e0c64068187940a2f71
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LAMA2 KCP LAMB1 SLIT2

6.83e-06184304102b6f621a5b551e622f97b12d787c080b052a72
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LAMA2 KCP LAMB1 SLIT2

6.83e-06184304689a8af81a79a4bb3123cfa01958c953eab5de98
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LAMA2 KCP LAMB1 SLIT2

6.83e-06184304327ff3ac8d2fecdd5d242bdc34f0dfdb1c59a68b
ToppCelldroplet-Liver-LIVER_HEP-30m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 IER5L MYLIP PEAR1

6.98e-06185304bdd2e6cb20294b39a9d856004bf57ba69cf877e2
ToppCellCOVID-19-Heart-Fib_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

LAMA2 LAMB1 SLIT2 PLA2G5

6.98e-061853048f95d8e591bf7379d13f5a0545b0cb49e2b1ab5d
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D175|Adult / Lineage, Cell type, age group and donor

LAMA2 LAMB1 SLIT2 PLA2G5

7.28e-06187304e15d2967aac248da3517bc2c7d1beaa1d5a0aa7f
ToppCellLA-01._Fibroblast_I|World / Chamber and Cluster_Paper

LAMA2 SLIT2 PLA2G5 EGFR

7.28e-061873044ea486991f66c29728d127171a07b81404ec0b78
ToppCellAT1_cells-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

BRINP2 HSPG2 FRAS1 SUSD2

7.28e-06187304f1dda349335e08dbfc8395d373924037f5ad2fd6
ToppCellControl-Fibroblasts-Alveolar_FB|Control / group, cell type (main and fine annotations)

LAMA2 LAMB1 SLIT2 FRAS1

7.28e-0618730492d468dde81125d51daf7abd4703741abe1ab91c
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Lobular_Carcinoma-6|TCGA-Breast / Sample_Type by Project: Shred V9

LAMA2 SLIT2 MEGF6 PEAR1

7.43e-06188304c90669b51e1902fe7726555290c91c92a911df83
ToppCell10x3'2.3-week_14-16-Mesenchymal_myocytic-stroma-muscle_stem_cell|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

LAMA2 SLIT2 HSPG2 FRAS1

7.43e-06188304de6f4889e0c5f39fbbaefd85526f645c6afa09d5
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

LAMA2 SLIT2 FGF10 FRAS1

7.59e-06189304203c80030df08ae112f9ae4043709f455d87ce89
ToppCellLV-14._Fibroblast_III|World / Chamber and Cluster_Paper

LAMB1 SLIT2 FGF10 EGFR

7.59e-061893043922135d1f6fc768d71ba3b465585fead6ea68a8
ToppCellMesenchymal-pericyte_cell|World / Lineage, Cell type, age group and donor

LAMA2 KCP LAMB1 PEAR1

7.59e-06189304d7ed96add29f219183c802895fbff519b627f635
ToppCelldroplet-Mammary_Gland-nan-3m-Mesenchymal|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA2 LAMB1 HSPG2 EGFR

7.75e-06190304bd0d68dc1b6f388190a6ba8a83b011619abe2bdd
ToppCelldroplet-Mammary_Gland-nan-3m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA2 LAMB1 HSPG2 EGFR

7.75e-06190304e275de94468872e70cf305b3b450823d4c9c5e3f
ToppCelldroplet-Mammary_Gland-nan-3m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA2 LAMB1 HSPG2 EGFR

7.75e-06190304ee2f4a55d2fd18b83e55399b5b5697a15a2d2e70
ToppCellASK454-Mesenchymal-Fibroblast|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

LAMA2 LAMB1 SLIT2 FRAS1

7.91e-061913041726add3f392a061536b7aff72ba84303f4a0b1f
ToppCellhuman_hepatoblastoma-Hepatic_Stellate_cells|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)

LAMA2 SLIT2 PLA2G5 PEAR1

7.91e-0619130478c3c2fdb68c3407f2436f90e1e6a780bbf8b79e
ToppCelldroplet-Lung-30m-Mesenchymal-fibroblast|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LAMA2 LAMB1 SLIT2 FGF10

7.91e-06191304cd497abed9e00e4e0becd9dbc036c6e7a60ae791
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

LAMA2 LAMB1 SLIT2 FRAS1

7.91e-061913046688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCellASK454-Mesenchymal|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

LAMA2 LAMB1 SLIT2 FRAS1

7.91e-06191304e30ae7a12439f8a79820b13f03e822c1223fd0cb
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

LAMA2 LAMB1 SLIT2 FRAS1

8.08e-0619230499ce9e3c4c50cf64ebb62145f2b5420efa0db309
ToppCellfacs-Pancreas-Exocrine-3m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA2 LAMB1 SLIT2 HSPG2

8.08e-06192304ac1477433704573f95111eee6263b93668d2845e
ToppCelldroplet-Lung-30m-Mesenchymal|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LAMA2 LAMB1 SLIT2 FGF10

8.08e-061923045d5bec238b196f0b3e727fd94f078d6ae524cb01
ToppCelldroplet-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l49|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LAMA2 LAMB1 SLIT2 FGF10

8.08e-061923041b228f0929b505de82a39bf64c837887b0e56701
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LAMA2 LAMB1 HSPG2 EGFR

8.08e-0619230432acd89617934016cd135d2cc797e8e79ae1b37f
ToppCellfacs-Lung-nan-3m-Mesenchymal-Adventitial_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA2 LAMB1 HSPG2 EGFR

8.08e-06192304a2c31390da4962bda9a936470b0b68fa1f5d47d1
ToppCellfacs-Pancreas-Exocrine-3m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA2 LAMB1 SLIT2 HSPG2

8.08e-061923048937a59f6bbe07f671bdabbd3707dc9c17a14cd9
ToppCellPND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LAMA2 KCP LAMB1 PEAR1

8.08e-06192304158cc5736f154da1cb3186ffbf186eae10483e48
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LAMA2 LAMB1 HSPG2 EGFR

8.08e-061923047b48df661f61ce494bf6f0b9a74b0422e29c24bf
ToppCellfacs-Lung-nan-3m-Mesenchymal-adventitial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA2 LAMB1 HSPG2 EGFR

8.08e-06192304eeab1cef7c36ae824381952c5b2c982368c379fd
ToppCelldroplet-Limb_Muscle-nan-18m-Mesenchymal-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA2 LAMB1 HSPG2 EGFR

8.08e-061923042d9e2262f1342fe17735f21f733c029d1275e955
ToppCellfacs-Pancreas-Exocrine-3m-Mesenchymal|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA2 LAMB1 SLIT2 HSPG2

8.08e-06192304e4a7f2673f801b008ca67291db2fb2b9fd2955b8
ToppCellPND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LAMA2 KCP LAMB1 PEAR1

8.08e-06192304f4ff62ac9c53eafbe917706de9af8b2d4bded4d4
ToppCelldroplet-Lung-30m-Mesenchymal-fibroblast-adventitial_fibroblast|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LAMA2 LAMB1 HSPG2 FGF10

8.24e-061933049d0b966d13cbce97beb43de6dc77f006c363a181
ToppCellPND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LAMA2 LAMB1 SLIT2 FGF10

8.24e-061933044c74a3f69b2cbdf139e7e66b44bd86869ac34dc0
ToppCellPND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LAMA2 LAMB1 SLIT2 FGF10

8.24e-06193304ff8ceeb3cfd1bef7239df490c19d181091750833
ToppCellfacs-Lung-nan-3m-Mesenchymal|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA2 LAMB1 HSPG2 EGFR

8.24e-06193304d9c20a092b507c43fcf7ccb04073fecd27d1749c
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

LAMA2 LAMB1 SLIT2 FGF10

8.24e-06193304b3ad5ff480d99217f36cc7471e5a96a519ddb409
ToppCelldroplet-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LAMA2 LAMB1 HSPG2 FGF10

8.24e-06193304fe9720185929ef849edd1b8eb4854306b392e5a2
ToppCellCOVID-19-Fibroblasts-Other_FB|COVID-19 / group, cell type (main and fine annotations)

LAMA2 LAMB1 SLIT2 FGF10

8.24e-06193304e6b75be08e33c1de079fb5c02f0b4468128b369c
ToppCellCOVID-19-Heart-Fib_2|Heart / Disease (COVID-19 only), tissue and cell type

LAMA2 LAMB1 SLIT2 EGFR

8.41e-06194304d91c9f2ec47319051fc398320693fddbe8bbd4d6
ToppCell3'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAMA2 LAMB1 SLIT2 FGF10

8.41e-06194304e2db75f4de114631b8bda4e188f84446545538b7
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

LAMA2 LAMB1 SLIT2 FRAS1

8.41e-0619430435f132cc38ac133be01834ed0946188aa0757eb4
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

LAMA2 LAMB1 SLIT2 FGF10

8.41e-06194304011e14d9ed1393275f892060e7708ffadcd0767f
ToppCellLV-14._Fibroblast_III|LV / Chamber and Cluster_Paper

LAMB1 SLIT2 FGF10 EGFR

8.41e-06194304927c26aea0147f7a4b8fb3f192de4de263f1b978
ToppCellLA-02._Fibroblast_II|LA / Chamber and Cluster_Paper

LAMA2 SLIT2 PLA2G5 EGFR

8.41e-06194304234d1494c114cce77c619708bbcd8d5ce805f19b
ToppCellfacs-GAT-Fat-3m-Mesenchymal-mesenchymal_progenitor|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA2 LAMB1 HSPG2 EGFR

8.58e-0619530469a29d03e664b72f32d41876510c62345c3aed31
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LAMA2 LAMB1 SLIT2 FGF10

8.58e-061953044243190ad291d56694e2155954dbaa879c9d3844
ToppCellfacs-GAT-Fat-3m-Mesenchymal|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA2 LAMB1 HSPG2 EGFR

8.58e-061953041cffae2b08dbfa1c633ce24023e89b66d28b5431
ToppCellBronchial-NucSeq-Stromal-Fibroblastic-Fibro_myofibroblast|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

BRINP2 LAMA2 LAMB1 SLIT2

8.58e-06195304f5e91ce20a7ce528dc4c1a968c7bf096bf45c528
ToppCellfacs-Lung-3m|Lung / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LAMA2 LAMB1 HSPG2 EGFR

8.58e-06195304c4648c0332c3826776f9ad3f5f803dbac2b4c0c0
ToppCellLA-02._Fibroblast_II|World / Chamber and Cluster_Paper

LAMA2 SLIT2 PLA2G5 EGFR

8.58e-06195304a78b605b49acd8c9d68716266ca269dafcd910b9
ToppCellfacs-GAT-Fat-3m-Mesenchymal-mesenchymal_stem_cell_of_adipose|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA2 LAMB1 HSPG2 EGFR

8.58e-061953049cef6f18664518060af7c192310dddce6d70345a
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LAMA2 LAMB1 SLIT2 FGF10

8.58e-06195304df409f94f4e83be89f7a608058ee07ce3ce3a149
ToppCell367C-Fibroblasts-Fibroblast-C_(Myofibroblast)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

LAMB1 SLIT2 PLA2G5 FRAS1

8.76e-061963046730743cf088c419ccc2d28765769fc09d3ba6a7
ToppCellfacs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LAMA2 LAMB1 FGF10 EGFR

8.76e-06196304d4676a6b0d9e417795fc9a6bcb1762d3dd656ca9
ToppCellfacs-Lung-nan|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA2 LAMB1 HSPG2 EGFR

8.76e-06196304b05f77f3990b662682ffeaf0e4c2fb190e0a6e65
ToppCell367C-Fibroblasts-Fibroblast-C_(Myofibroblast)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

LAMB1 SLIT2 PLA2G5 FRAS1

8.76e-0619630421dab89f3699037138a9c7a0e4dc98739a9fad9c
ToppCellfacs-Lung-nan-3m|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA2 LAMB1 HSPG2 EGFR

8.76e-06196304787c6cd92035e0b1108c2c086c42a229016e476b
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

LAMA2 LAMB1 SLIT2 FGF10

8.94e-0619730444673c38384453207871d3fd8e8ba9093cc06bc5
ToppCellCOPD-Stromal-Myofibroblast|World / Disease state, Lineage and Cell class

LAMA2 LAMB1 SLIT2 EGFR

8.94e-06197304d51f484b4e01ac64233950d0b97fa88825ea1dbb
DrugN-(2-(4-((3-chloro-4-(3-(trifluoromethyl)phenoxy)phenyl)amino)-5H-pyrrolo(3,2-d)pyrimidin-5-yl)ethyl)-3-hydroxy-3-methylbutanamide

ERBB2 EGFR

1.68e-062302ctd:C570404
DrugLapatinib

ERBB2 EGFR

1.68e-062302DB01259
Drug2-acetamidoethanethiol

ERBB2 EGFR

5.03e-063302ctd:C023704
Drug4557 W

ERBB2 EGFR

5.03e-063302ctd:C433938
Drug4-aminopyrimidine-5-carbaldehyde

ERBB2 EGFR

5.03e-063302CID011228787
Drugpyrido[3,4-d]pyrimidine

ERBB2 EGFR

5.03e-063302CID014758064
Drug5-iodonicotinic acid

ERBB2 EGFR

5.03e-063302CID000151950
DrugEGFR/ErbB2 inhibitor

ERBB2 EGFR

1.01e-054302CID009843206
Drugtyrphostin AG825

ERBB2 EGFR

1.01e-054302CID000002062
DrugTAK-165

ERBB2 EGFR

1.67e-055302CID006444692
DrugB-31

ERBB2 EGFR

2.51e-056302CID000122475
DrugZD-6

ERBB2 EGFR

2.51e-056302CID010062753
DrugAC1L1JJ0

ERBB2 EGFR

3.51e-057302CID000005061
Drugdeazapurine

ERBB2 EGFR

3.51e-057302CID000261591
DrugPKI 166

ERBB2 EGFR

3.51e-057302ctd:C410026
Drugsecoisolariciresinol diglucoside

ERBB2 EGFR

3.51e-057302ctd:C090142
DrugFolfox protocol

ERBB2 EGFR

4.68e-058302ctd:C410216
Drugkalinin

LAMA2 LAMB1 HSPG2

5.17e-0555303CID000032518
Drugvinyl sulfonamide

ERBB2 EGFR

6.01e-059302CID000520075
Drugbut-2-enamide

ERBB2 EGFR

6.01e-059302CID000031877
Drug6-(methylamino)pyrido(3,4-d)pyrimidine

ERBB2 EGFR

7.50e-0510302ctd:C107875
Drugsulfo-MBS

ERBB2 EGFR

9.16e-0511302CID000124851
DrugGW2974

ERBB2 EGFR

9.16e-0511302CID006603857
DrugAC1L1G72

LAMA2 LAMB1

9.16e-0511302CID000003553
DrugBE-23372M

ERBB2 EGFR

9.16e-0511302CID005311105
Drugcompound 56

ERBB2 EGFR

9.16e-0511302CID000002857
DrugN-methyl-3-(1-(4-(piperazin-1-yl)phenyl)-5-(4'-(trifluoromethyl)-(1,1'-biphenyl)-4-yl)-1H-pyrazol-3-yl)propanamide

ERBB2 EGFR

1.10e-0412302ctd:C562238
DrugAC1L28C4

ERBB2 EGFR

1.10e-0412302CID000042675
DrugCanertinib

ERBB2 EGFR

1.10e-0412302ctd:C420268
DrugNorgestrel-(-)-D [797-63-7]; Up 200; 12.8uM; PC3; HT_HG-U133A

MUC5B MEGF6 MEGF8 EGFR

1.15e-041933043708_UP
DrugDropropizine (R,S) [17692-31-8]; Up 200; 17uM; MCF7; HT_HG-U133A

LAMA2 PLA2G5 HSPG2 DEAF1

1.18e-041943045531_UP
Drug2-propylpentanoic acid; Down 200; 1000uM; PC3; HG-U133A

HSPG2 MUC5B DEAF1 EGFR

1.18e-04194304433_DN
DrugBenperidol [2062-84-2]; Up 200; 10.4uM; MCF7; HT_HG-U133A

BRINP2 HSPG2 MUC5B MEGF6

1.20e-041953044781_UP
DrugBicuculline (+) [485-49-4]; Down 200; 10.8uM; MCF7; HT_HG-U133A

HSPG2 ERBB2 DEAF1 EGFR

1.25e-041973042796_DN
DrugCMF regimen

ERBB2 EGFR

1.30e-0413302ctd:C034456
DrugTrastuzumab

ERBB2 EGFR

1.30e-0413302DB00072
DrugFurazolidone [67-45-8]; Up 200; 17.8uM; MCF7; HT_HG-U133A

BRINP2 PLA2G5 MUC5B CCN3

1.30e-041993044178_UP
DrugA0395

LAMB1 ERBB2 FURIN

1.31e-0475303CID009906466
DrugFK-506; Up 200; 1uM; MCF7; HG-U133A

ERBB2 KDM4A MEGF6 CCN3

1.32e-04200304378_UP
DrugCarbarsone [121-59-5]; Down 200; 15.4uM; PC3; HT_HG-U133A

HSPG2 DEAF1 EGFR MYLIP

1.32e-042003043991_DN
Drug2-amino-5-methylpyridine

LAMA2 LAMB1 FURIN

1.41e-0477303CID000015348
DrugTapi

ERBB2 EGFR FURIN

1.58e-0480303CID003035404
DrugAntineoplastic Agents

ERBB2 EGFR

1.74e-0415302ctd:D000970
DrugNVP-TAE684

ERBB2 EGFR

1.74e-0415302ctd:C516714
Drug2-[(1R,2R,3S,4R,5R,6S)-2-[(2R,5S)-3-[(3S,4S,5R,6S)-4,5-dihydroxy-3-(methylamino)-6-methylol-tetrahydropyran-2-yl]-4-formyl-4-hydroxy-5-methylol-tetrahydrofuran-2-yl]oxy-5-guanidino-3,4,6-trihydroxy-cyclohexyl]guanidine

LAMA2 LAMB1 ERBB2

1.77e-0483303CID011968896
DrugAC1L1G2K

ERBB2 EGFR FURIN

1.83e-0484303CID000003498
DrugNSC 714187

LAMA2 LAMB1 FURIN

1.90e-0485303CID005288693
DrugLMWH

LAMA2 LAMB1 SLIT2 HSPG2 FGF10 EGFR

1.95e-04663306CID000000772
Druglapatinib

HSPG2 ERBB2 EGFR

1.96e-0486303CID000208908
Drug4-anilinoquinazoline

ERBB2 EGFR

1.99e-0416302CID000324081
Drugsulfate

LAMA2 LAMB1 SLIT2 HSPG2 FGF10 ERBB2 EGFR FURIN

2.00e-041292308CID000001117
DrugMEN 11420

HSPG2 DEAF1

2.25e-0417302CID003086682
DrugCL-387,785

ERBB2 EGFR

3.14e-0420302CID000002776
DrugNSC740137

FGF10 ERBB2 EGFR

3.34e-04103303CID000003817
Drugcapecitabine

PLA2G5 ERBB2 EGFR

3.44e-04104303CID000060953
Drug6)-gingerol

ERBB2 EGFR

3.47e-0421302CID000090942
Drugphenadoxone

ERBB2 EGFR

3.81e-0422302CID000010089
Drugbosutinib

ERBB2 EGFR

3.81e-0422302ctd:C471992
DrugMethylnitronitrosoguanidine

FGF10 ERBB2 DEAF1 EGFR

3.87e-04265304ctd:D008769
DrugAC1L1C2F

LAMB1 HSPG2 EGFR

4.05e-04110303CID000001711
DrugAC1L1CT9

ERBB2 EGFR

4.17e-0423302CID000002054
DrugPHA665752

ERBB2 EGFR

4.17e-0423302CID010461815
Drughydroxytamoxifen

ERBB2 CCN3 MYLIP

4.85e-04117303ctd:C475919
DrugQuinazolines

ERBB2 EGFR

4.94e-0425302ctd:D011799
Druggenistein

LAMA2 LAMB1 HSPG2 ERBB2 EGFR FURIN MYLIP

5.06e-041117307CID005280961
DrugReserpine

HSPG2 ERBB2 FURIN

5.10e-04119303ctd:D012110
Drug94 PU

HSPG2 EGFR

5.35e-0426302CID000023940
DrugBIBX1382BS

ERBB2 EGFR

5.35e-0426302CID006918508
DrugNVP & EFV

FGF10 ERBB2 EGFR

5.35e-04121303CID000492400
DrugArsenates

LAMA2 LAMB1 FGF10

5.48e-04122303ctd:D001149
DrugCaspofungin [inn]

HSPG2 FGF10

5.77e-0427302CID000151068
Drugbenzylidenemalononitrile

ERBB2 EGFR

5.77e-0427302CID000017608
Drugsaracatinib

ERBB2 EGFR

5.77e-0427302CID010302451
DiseaseCetuximab response

ERBB2 EGFR

8.05e-065272cv:CN077967
DiseasePanitumumab response

ERBB2 EGFR

8.05e-065272cv:CN077999
DiseaseHead and Neck Carcinoma

ERBB2 EGFR

3.61e-0510272C3887461
Diseasegallbladder neoplasm

ERBB2 EGFR

4.41e-0511272C0016978
DiseaseMalignant neoplasm of gallbladder

ERBB2 EGFR

4.41e-0511272C0153452
DiseasePapilloma

ERBB2 EGFR

5.29e-0512272C0030354
DiseasePapillomatosis

ERBB2 EGFR

5.29e-0512272C0205875
DiseasePapilloma, Squamous Cell

ERBB2 EGFR

5.29e-0512272C0205874
DiseaseLung cancer

ERBB2 EGFR

7.29e-0514272cv:C0242379
DiseaseLUNG CANCER

ERBB2 EGFR

7.29e-0514272211980
Diseasemedian neuropathy (biomarker_via_orthology)

ERBB2 EGFR

7.29e-0514272DOID:571 (biomarker_via_orthology)
DiseaseNeoplasm of lung

ERBB2 EGFR

7.29e-0514272cv:C0024121
Diseaseurinary bladder cancer (is_marker_for)

ERBB2 KDM4A EGFR

1.27e-04107273DOID:11054 (is_marker_for)
Diseaselaryngeal squamous cell carcinoma (is_marker_for)

ERBB2 EGFR

1.37e-0419272DOID:2876 (is_marker_for)
DiseasePolydactyly

FGF10 FRAS1 MEGF8

1.66e-04117273C0152427
Diseasehypertension

KCP KDM4A FURIN CCN3

1.67e-04307274EFO_0000537
DiseaseCarcinoma of lung

ERBB2 EGFR

2.02e-0423272C0684249
DiseaseIntrahepatic Cholangiocarcinoma

ERBB2 EGFR

2.20e-0424272C0345905
Diseasestomach carcinoma (is_marker_for)

ERBB2 KDM4A

2.20e-0424272DOID:5517 (is_marker_for)
DiseaseExtrahepatic Cholangiocarcinoma

ERBB2 EGFR

2.20e-0424272C3805278
DiseaseCholangiocarcinoma

ERBB2 EGFR

2.59e-0426272C0206698
DiseaseMammary Carcinoma, Animal

ERBB2 EGFR FURIN

2.93e-04142273C1257925
DiseaseAnimal Mammary Neoplasms

ERBB2 EGFR FURIN

2.93e-04142273C0024667
DiseaseMammary Neoplasms, Experimental

ERBB2 EGFR FURIN

3.79e-04155273C0024668
Diseaseintestinal cancer (implicated_via_orthology)

ERBB2 EGFR

3.93e-0432272DOID:10155 (implicated_via_orthology)
DiseaseHead and Neck Neoplasms

ERBB2 EGFR

4.18e-0433272C0018671
DiseaseEndometrioma

LAMB1 EGFR MYLIP

4.24e-04161273C0269102
DiseaseEndometriosis

LAMB1 EGFR MYLIP

4.24e-04161273C0014175
Diseaseretinal detachment, retinal break

LAMA2 FRAS1

4.71e-0435272EFO_0005773, EFO_0010698
Diseasevisceral heterotaxy (implicated_via_orthology)

SLIT2 MEGF8

5.26e-0437272DOID:0050545 (implicated_via_orthology)
DiseaseNeoplasm Recurrence, Local

ERBB2 EGFR

5.85e-0439272C0027643
DiseaseCongenital small ears

FGF10 FRAS1

6.47e-0441272C0152423
DiseaseMalignant Head and Neck Neoplasm

ERBB2 EGFR

7.45e-0444272C0278996
Diseaselung adenocarcinoma (is_implicated_in)

ERBB2 EGFR

9.23e-0449272DOID:3910 (is_implicated_in)
Diseaseattention deficit hyperactivity disorder, bipolar disorder, autism spectrum disorder, schizophrenia, major depressive disorder

KDM4A FURIN

1.00e-0351272EFO_0003756, EFO_0003888, MONDO_0002009, MONDO_0004985, MONDO_0005090
DiseaseSmall cell carcinoma of lung

SLIT2 EGFR

1.12e-0354272C0149925
Diseasepre-eclampsia (is_marker_for)

ERBB2 CCN3

1.29e-0358272DOID:10591 (is_marker_for)
Diseasetransitional cell carcinoma (is_marker_for)

ERBB2 EGFR

1.52e-0363272DOID:2671 (is_marker_for)
Diseaseoral squamous cell carcinoma (is_marker_for)

ERBB2 EGFR

1.52e-0363272DOID:0050866 (is_marker_for)
Diseasecarcinoma (implicated_via_orthology)

ERBB2 EGFR

1.57e-0364272DOID:305 (implicated_via_orthology)
DiseaseParkinson's disease (is_marker_for)

ERBB2 EGFR

1.72e-0367272DOID:14330 (is_marker_for)

Protein segments in the cluster

PeptideGeneStartEntry
GACQPCPINCTHSCV

ERBB2

621

P04626
CFSTHCVSGCVCPPG

MUC5B

826

Q9HC84
CSGCNCNGHASSCDP

HSPG2

761

P98160
CQPCNTHCGSCDSQA

FRAS1

906

Q86XX4
HKCENPCHAGSCQPC

NFXL1

321

Q6ZNB6
ACQFRCQCHGAPCDP

PEAR1

186

Q5VY43
CQCHGAPCDPQTGAC

PEAR1

191

Q5VY43
CQSHGQCQPPGVCAC

MEGF8

146

Q7Z7M0
AGCCVQCSHGRCPTA

KDM4A

841

O75164
PCGHTVCCESCAAQL

MYLIP

401

Q8WY64
CDPCNCNAAHSFGPS

LAMB1

1081

P07942
CAASPPNCCHPSCCQ

KRTAP4-16

16

G5E9R7
PQCCHSVCFQPTCCH

KRTAP4-16

91

G5E9R7
TCVPCQCNGHSSLCD

LAMA2

1416

P24043
TCEPGPFCHVNLCAC

PLA2G5

96

P39877
KSPSDCCHNQCAAGC

EGFR

226

P00533
FCGVCSDGRCCTPHN

CCN3

291

P48745
ILNPHAASCTCAACC

DEAF1

271

O75398
CAPCHASCATCQGPA

FURIN

641

P09958
ACPESCCEPHCCALS

KRTAP10-1

21

P60331
QSSCHPACCTSSPCQ

KRTAP10-1

166

P60331
CQPACCTSSPCQHAC

KRTAP10-6

256

P60371
CQHACCVPVCSGAST

KRTAP10-6

266

P60371
PASSCQPSCCHPASC

KRTAP10-8

231

P60410
QPSCCHPASCLSFLC

KRTAP10-8

236

P60410
LCANVECPPAHTCPC

CRIPAK

6

Q8N1N5
HTCPCGVPACSCAHV

CRIPAK

16

Q8N1N5
ECSPAHTCRCGVPAC

CRIPAK

196

Q8N1N5
SAFPHLPGCCCCCFL

FGF10

11

O15520
CCASAHCPCCGQGAP

IER5L

276

Q5T953
NPACHPATGTCSCAA

MEGF6

1181

O75095
PCSCHPTCSGLGTCC

SUSD2

41

Q9UGT4
DPCSHCRCANGSVQC

KCP

331

Q6ZWJ8
AGPHSCSCATCPCSS

SPATA3

106

Q8NHX4
CAHCAPDNSTRCGSC

BRINP2

466

Q9C0B6
CPPNASCVNNTHCTC

ADGRE3

31

Q9BY15
PSCSVLHCPAACTCS

SLIT2

266

O94813
HSNCPCVCALDGPVC

VWC2L

71

B2RUY7