Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncomplement component C3b binding

CFH CFHR4 CFHR3

5.57e-0612603GO:0001851
GeneOntologyMolecularFunctionopsonin binding

CFH CFHR4 CFHR3

5.66e-0525603GO:0001846
GeneOntologyMolecularFunctioncomplement binding

CFH CFHR4 CFHR3

1.20e-0432603GO:0001848
GeneOntologyBiologicalProcessresponse to dietary excess

CFH APPL2 WNK4 CFHR4

9.82e-0647594GO:0002021
GeneOntologyCellularComponentsymbiont cell surface

CFH CFHR4

2.40e-048622GO:0106139
GeneOntologyCellularComponentother organism part

CFH CFHR4

3.07e-049622GO:0044217
MousePhenoartery occlusion

CFH CFHR4

1.11e-052472MP:0006134
MousePhenoabnormal hepatic portal vein thrombosis

CFH CFHR4

1.11e-052472MP:0031159
MousePhenowhite pupil

CFH CFHR4

1.11e-052472MP:0006242
MousePhenodecreased serum complement activity

CFH CFHR4

1.11e-052472MP:0012553
MousePhenodecreased complement C5 level

CFH CFHR4

1.11e-052472MP:0012609
MousePhenoabnormal complement C5 level

CFH CFHR4

1.11e-052472MP:0012608
MousePhenoabnormal kidney venous thrombosis

CFH CFHR4

3.31e-053472MP:0031161
MousePhenoincreased susceptilbility to retina ischemic injury

CFH CFHR4

3.31e-053472MP:0012049
MousePhenoincreased susceptibility to type III hypersensitivity reaction

CFH CFHR4

6.61e-054472MP:0005615
MousePhenomesangial cell interposition

CFH CFHR4

6.61e-054472MP:0011512
MousePhenoabnormal brain thrombosis

CFH CFHR4

6.61e-054472MP:0031168
MousePhenoabnormal response to retina ischemic injury

CFH CFHR4

6.61e-054472MP:0012048
MousePhenodecreased circulating complement protein level

CFH CFHR4

6.61e-054472MP:0020216
MousePhenoincreased creatine level

CFH CFHR4

6.61e-054472MP:0010061
MousePhenoabnormal venous thrombosis

CFH CFHR4

1.10e-045472MP:0031158
MousePhenoabnormal lung thrombosis

CFH CFHR4

1.10e-045472MP:0031167
MousePhenoabnormal gas homeostasis

CLSTN3 SEPSECS GPR50 ZFHX4 STAC3 KIF5A EPAS1 WNK4 CLDN2

1.47e-04600479MP:0003948
MousePhenoabnormal circulating complement protein level

CFH CFHR4

1.65e-046472MP:0010215
MousePhenoabnormal somatic nervous system physiology

TAS1R3 L1CAM SLC26A5 EPAS1

1.70e-0483474MP:0005423
MousePhenorenal glomerular immunoglobulin deposits

CFH TLR7 CFHR4

1.98e-0434473MP:0020519
MousePhenoabnormal oxygen level

SEPSECS ZFHX4 STAC3 KIF5A EPAS1 CLDN2

2.04e-04256476MP:0001574
MousePhenoabnormal glomerular capillary thrombosis

CFH CFHR4

2.30e-047472MP:0011508
MousePhenobrain ischemia

CFH CFHR4

3.06e-048472MP:0006080
MousePhenorenal glomerular protein deposits

CFH TLR7 CFHR4

3.73e-0442473MP:0020518
MousePhenoabnormal complement protein level

CFH CFHR4

3.92e-049472MP:0011566
MousePhenoabnormal creatine level

CFH CFHR4

3.92e-049472MP:0010060
MousePhenoexpanded mesangial matrix

CFH TLR7 CFHR4

4.89e-0446473MP:0011353
MousePhenoabnormal type III hypersensitivity reaction

CFH CFHR4

4.89e-0410472MP:0002533
MousePhenoabnormal kidney thrombosis

CFH CFHR4

4.89e-0410472MP:0011507
MousePhenoabnormal mesangial matrix morphology

CFH TLR7 CFHR4

6.62e-0451473MP:0011338
MousePhenoparalysis

CFH L1CAM STAC3 CFHR4

6.71e-04119474MP:0000753
MousePhenoabnormal visual acuity

CFH CFHR4

8.43e-0413472MP:0011832
MousePhenodecreased visual acuity

CFH CFHR4

8.43e-0413472MP:0006149
MousePhenoabnormal Bruch membrane morphology

CFH CFHR4

9.81e-0414472MP:0005239
MousePhenodecreased mean corpuscular hemoglobin concentration

SEPSECS APPL2 MKRN2 TENT5C

1.11e-03136474MP:0005642
MousePhenoretina detachment

CFH CFHR4

1.13e-0315472MP:0003099
DomainSushi

CFH CFHR4 CFHR3

5.93e-0452593PF00084
DomainCCP

CFH CFHR4 CFHR3

6.62e-0454593SM00032
DomainSUSHI

CFH CFHR4 CFHR3

7.37e-0456593PS50923
DomainPMG

KRTAP25-1 KRTAP24-1

7.48e-0413592PF05287
DomainKRTAP_PMG

KRTAP25-1 KRTAP24-1

7.48e-0413592IPR007951
DomainSushi_SCR_CCP_dom

CFH CFHR4 CFHR3

7.76e-0457593IPR000436
DomainCNH

CDC42BPA NRK

8.71e-0414592SM00036
DomainCNH

CDC42BPA NRK

1.00e-0315592PF00780
DomainCNH

CDC42BPA NRK

1.00e-0315592PS50219
DomainCNH_dom

CDC42BPA NRK

1.00e-0315592IPR001180
Domain-

CLSTN3 NRXN1 USH2A

3.37e-03955932.60.120.200
PathwayKEGG_MEDICUS_REFERENCE_REGULATION_OF_COMPLEMENT_CASCADE_CFHR

CFH CFHR4 CFHR3

5.64e-076443M47880
PathwayREACTOME_COMPLEMENT_CASCADE

IGKV1-39 CFH IGKV1D-39 CFHR4 CFHR3

2.79e-05115445M19752
Pubmed

Two factor H-related proteins from the mouse: expression analysis and functional characterization.

CFH CFHR4 CFHR3

5.39e-09362317028856
Pubmed

Localization of complement factor H gene expression and protein distribution in the mouse outer retina.

CFH CFHR4 CFHR3

5.39e-09362325684976
Pubmed

CFH and CFHR structural variants in atypical Hemolytic Uremic Syndrome: Prevalence, genomic characterization and impact on outcome.

CFH CFHR4 CFHR3

2.16e-08462336793547
Pubmed

Identification and sequence analysis of four complement factor H-related transcripts in mouse liver.

CFH CFHR4 CFHR3

5.38e-0856231689298
Pubmed

Molecular basis of C-reactive protein binding and modulation of complement activation by factor H-related protein 4.

CFH CFHR4 CFHR3

5.38e-08562320042240
Pubmed

A radiation hybrid map of complement factor H and factor H-related genes.

CFH CFHR4 CFHR3

5.38e-08562310380701
Pubmed

Sequence and Expression of Complement Factor H Gene Cluster Variants and Their Roles in Age-Related Macular Degeneration Risk.

CFH CFHR4 CFHR3

1.07e-07662327196323
Pubmed

Extended haplotypes in the complement factor H (CFH) and CFH-related (CFHR) family of genes protect against age-related macular degeneration: characterization, ethnic distribution and evolutionary implications.

CFH CFHR4 CFHR3

1.07e-07662317438673
Pubmed

Association of factor H autoantibodies with deletions of CFHR1, CFHR3, CFHR4, and with mutations in CFH, CFI, CD46, and C3 in patients with atypical hemolytic uremic syndrome.

CFH CFHR4 CFHR3

1.88e-07762319861685
Pubmed

Epidemiological approach to identifying genetic predispositions for atypical hemolytic uremic syndrome.

CFH CFHR4 CFHR3

4.50e-07962320059470
Pubmed

FHR-1 Binds to C-Reactive Protein and Enhances Rather than Inhibits Complement Activation.

CFH CFHR4 CFHR3

4.50e-07962328533443
Pubmed

Genetic Atypical Hemolytic-Uremic Syndrome

CFH CFHR4 CFHR3

8.81e-071162320301541
Pubmed

Complement Factor H Modulates Splenic B Cell Development and Limits Autoantibody Production.

CFH CFHR4

3.13e-06262231354740
Pubmed

Absence of complement factor H reduces physical performance in C57BL6 mice.

CFH CFHR4

3.13e-06262232962822
Pubmed

Transgenic mice expressing variants of complement factor H develop AMD-like retinal findings.

CFH CFHR4

3.13e-06262220538999
Pubmed

Inheritance, hormonal regulation and properties of polymorphic murine antigens Mud1 and Mud2.

CFH CFHR4

3.13e-0626224992636
Pubmed

Retinal changes precede visual dysfunction in the complement factor H knockout mouse.

CFH CFHR4

3.13e-06262223844226
Pubmed

Prediction from sequence comparisons of residues of factor H involved in the interaction with complement component C3b.

CFH CFHR4

3.13e-0626228615824
Pubmed

Cadmium Induces Glomerular Endothelial Cell-Specific Expression of Complement Factor H via the -1635 AP-1 Binding Site.

CFH CFHR4

3.13e-06262230642982
Pubmed

Partial Complement Factor H Deficiency Associates with C3 Glomerulopathy and Thrombotic Microangiopathy.

CFH CFHR4

3.13e-06262226374608
Pubmed

A gene locus concerned with an antigenic serum substance in Mus musculus.

CFH CFHR4

3.13e-0626224955525
Pubmed

Analysis of complement factor H mRNA expression: dexamethasone and IFN-gamma increase the level of H in L cells.

CFH CFHR4

3.13e-0626222533512
Pubmed

Complement factor H: spatial and temporal expression and localization in the eye.

CFH CFHR4

3.13e-06262216936129
Pubmed

Watching synchronous mitochondrial respiration in the retina and its instability in a mouse model of macular degeneration.

CFH CFHR4

3.13e-06262233558624
Pubmed

Genome-Wide Association Study Reveals Variants in CFH and CFHR4 Associated with Systemic Complement Activation: Implications in Age-Related Macular Degeneration.

CFH CFHR4

3.13e-06262229398083
Pubmed

Complement factor H Y402H polymorphism results in diminishing CD4+ T cells and increasing C-reactive protein in plasma.

CFH CFHR4

3.13e-06262237940659
Pubmed

Comparative analysis of the properties and ligand binding characteristics of CspZ, a factor H binding protein, derived from Borrelia burgdorferi isolates of human origin.

CFH CFHR4

3.13e-06262219620346
Pubmed

Downregulation of OCLN and GAS1 in clear cell renal cell carcinoma.

GAS1 OCLN

3.13e-06262228184927
Pubmed

Complement factor H regulates retinal development and its absence may establish a footprint for age related macular degeneration.

CFH CFHR4

3.13e-06262230705315
Pubmed

Occludin regulates macromolecule flux across the intestinal epithelial tight junction barrier.

OCLN CLDN2

3.13e-06262221415414
Pubmed

Genome-wide association study identifies variants in the CFH region associated with host susceptibility to meningococcal disease.

CFH CFHR3

3.13e-06262220694013
Pubmed

A complement factor H homolog, heparan sulfation, and syndecan maintain inversin compartment boundaries in C. elegans cilia.

CFH CFHR4

3.13e-06262233859044
Pubmed

Regulation of age-related macular degeneration-like pathology by complement factor H.

CFH CFHR4

3.13e-06262225991857
Pubmed

Activation of TLR7-mediated autophagy increases epileptic susceptibility via reduced KIF5A-dependent GABAA receptor transport in a murine model.

TLR7 KIF5A

3.13e-06262237258573
Pubmed

Genetic variation in CFH predicts phenytoin-induced maculopapular exanthema in European-descent patients.

CFH CFHR4

3.13e-06262229288229
Pubmed

Tumour extracellular vesicle-derived Complement Factor H promotes tumorigenesis and metastasis by inhibiting complement-dependent cytotoxicity of tumour cells.

CFH CFHR4

3.13e-06262233708358
Pubmed

Serological survey of complement factor H in common laboratory and wild mice: a new third allotype.

CFH CFHR4

3.13e-0626222522412
Pubmed

Absence of complement factor H alters bone architecture and dynamics.

CFH CFHR4

3.13e-06262230107932
Pubmed

Murine Factor H Co-Produced in Yeast With Protein Disulfide Isomerase Ameliorated C3 Dysregulation in Factor H-Deficient Mice.

CFH CFHR4

3.13e-06262234054871
Pubmed

Factor H binding to PspC of Streptococcus pneumoniae increases adherence to human cell lines in vitro and enhances invasion of mouse lungs in vivo.

CFH CFHR4

3.13e-06262217562771
Pubmed

Aged complement factor H knockout mice kept in a clean barriered environment have reduced retinal pathology.

CFH CFHR4

3.13e-06262227397653
Pubmed

Effect of Anti-C5a Therapy in a Murine Model of Early/Intermediate Dry Age-Related Macular Degeneration.

CFH CFHR4

3.13e-06262229392311
Pubmed

Phage display of a human antibody against Clostridium tetani toxin.

IGKV1-39 IGKV1D-39

3.13e-0626227926831
Pubmed

Complement Factor H-Related 3 Enhanced Inflammation and Complement Activation in Human RPE Cells.

CFH CFHR3

3.13e-06262234819935
Pubmed

The critical role of complement alternative pathway regulator factor H in allergen-induced airway hyperresponsiveness and inflammation.

CFH CFHR4

3.13e-06262222174452
Pubmed

Loss of Complement Factor H in Plasma Increases Endothelial Cell Migration.

CFH CFHR4

3.13e-06262228819420
Pubmed

Complement factor H genotypes impact risk of age-related macular degeneration by interaction with oxidized phospholipids.

CFH CFHR4

3.13e-06262222875704
Pubmed

Local complement factor H protects kidney endothelial cell structure and function.

CFH CFHR4

3.13e-06262234139209
Pubmed

Systemic administration of Abeta mAb reduces retinal deposition of Abeta and activated complement C3 in age-related macular degeneration mouse model.

CFH CFHR4

3.13e-06262223799019
Pubmed

Circulating FH Protects Kidneys From Tubular Injury During Systemic Hemolysis.

CFH CFHR4

3.13e-06262232849636
Pubmed

Complement factor h is critical in the maintenance of retinal perfusion.

CFH CFHR4

3.13e-06262219541934
Pubmed

Complement factor H deficiency in aged mice causes retinal abnormalities and visual dysfunction.

CFH CFHR4

3.13e-06262217921253
Pubmed

The role of complement dysregulation in AMD mouse models.

CFH CFHR4

3.13e-06262224664701
Pubmed

Mitochondrial decline precedes phenotype development in the complement factor H mouse model of retinal degeneration but can be corrected by near infrared light.

CFH CFHR4

3.13e-06262226149919
Pubmed

Murine protein H is comprised of 20 repeating units, 61 amino acids in length.

CFH CFHR4

3.13e-0626222940596
Pubmed

A receptor for the complement regulator factor H increases transmission of trypanosomes to tsetse flies.

CFH CFHR4

3.13e-06262232165615
Pubmed

Death by color: differential cone loss in the aging mouse retina.

CFH CFHR4

3.13e-06262224929970
Pubmed

Cfh genotype interacts with dietary glycemic index to modulate age-related macular degeneration-like features in mice.

CFH CFHR4

3.13e-06262224370827
Pubmed

Essential role of surface-bound complement factor H in controlling immune complex-induced arthritis.

CFH CFHR4

3.13e-06262223436934
Pubmed

Treatment with 670 nm light up regulates cytochrome C oxidase expression and reduces inflammation in an age-related macular degeneration model.

CFH CFHR4

3.13e-06262223469078
Pubmed

Topical cyclodextrin reduces amyloid beta and inflammation improving retinal function in ageing mice.

CFH CFHR4

3.13e-06262225921262
Pubmed

Complement factor h limits immune complex deposition and prevents inflammation and scarring in glomeruli of mice with chronic serum sickness.

CFH CFHR4

3.13e-06262215574507
Pubmed

Design and evaluation of meningococcal vaccines through structure-based modification of host and pathogen molecules.

CFH CFHR4

3.13e-06262223133374
Pubmed

Human complement factor H Y402H polymorphism causes an age-related macular degeneration phenotype and lipoprotein dysregulation in mice.

CFH CFHR4

3.13e-06262230808757
Pubmed

Binding of factor H to tubular epithelial cells limits interstitial complement activation in ischemic injury.

CFH CFHR4

3.13e-06262221544060
Pubmed

Role of ocular complement factor H in a murine model of choroidal neovascularization.

CFH CFHR4

3.13e-06262220813971
Pubmed

The specific α-neurexin interactor calsyntenin-3 promotes excitatory and inhibitory synapse development.

CLSTN3 NRXN1

3.13e-06262224094106
Pubmed

Location of the mouse complement factor H gene (cfh) by FISH analysis and replication R-banding.

CFH CFHR4

3.13e-0626221486806
Pubmed

A chimeric Cfh transgene leads to increased retinal oxidative stress, inflammation, and accumulation of activated subretinal microglia in mice.

CFH CFHR4

3.13e-06262226030099
Pubmed

Spontaneous hemolytic uremic syndrome triggered by complement factor H lacking surface recognition domains.

CFH CFHR4

3.13e-06262217517971
Pubmed

Treatment with human complement factor H rapidly reverses renal complement deposition in factor H-deficient mice.

CFH CFHR4

3.13e-06262220445496
Pubmed

Possible role of complement factor H in podocytes in clearing glomerular subendothelial immune complex deposits.

CFH CFHR4

3.13e-06262231133737
Pubmed

High-density lipoproteins are a potential therapeutic target for age-related macular degeneration.

CFH CFHR4

3.13e-06262232737203
Pubmed

A De Novo Deletion in the Regulators of Complement Activation Cluster Producing a Hybrid Complement Factor H/Complement Factor H-Related 3 Gene in Atypical Hemolytic Uremic Syndrome.

CFH CFHR3

3.13e-06262226490391
Pubmed

Distinct and separable roles of the complement system in factor H-deficient bone marrow chimeric mice with immune complex disease.

CFH CFHR4

3.13e-06262216597679
Pubmed

AAV Gene Augmentation of Truncated Complement Factor H Differentially Rescues Ocular Complement Dysregulation in a Mouse Model.

CFH CFHR4

3.13e-06262237471073
Pubmed

Complement Factor H Serum Levels Determine Resistance to Pneumococcal Invasive Disease.

CFH CFHR4

3.13e-06262226802141
Pubmed

Expression of human complement factor H prevents age-related macular degeneration-like retina damage and kidney abnormalities in aged Cfh knockout mice.

CFH CFHR4

3.13e-06262225447048
Pubmed

Structure of the murine complement factor H gene.

CFH CFHR4

3.13e-0626222972715
Pubmed

Complement factor H deficiency combined with smoking promotes retinal degeneration in a novel mouse model.

CFH CFHR4

3.13e-06262234775843
Pubmed

Genome-wide association study identifies susceptibility loci for IgA nephropathy.

CFH CFHR4 CFHR3

5.12e-061962321399633
Pubmed

Associations of CFHR1-CFHR3 deletion and a CFH SNP to age-related macular degeneration are not independent.

CFH CFHR3

9.37e-06362220581873
Pubmed

Complement factor H, FHR-3 and FHR-1 variants associate in an extended haplotype conferring increased risk of atypical hemolytic uremic syndrome.

CFH CFHR3

9.37e-06362226163426
Pubmed

Complement factor H: sequence analysis of 221 kb of human genomic DNA containing the entire fH, fHR-1 and fHR-3 genes.

CFH CFHR3

9.37e-06362210781834
Pubmed

Association assessment of copy number polymorphism and risk of age-related macular degeneration.

CFH CFHR3

9.37e-06362221856016
Pubmed

Human Genetic Disorders Resulting in Systemic Selenoprotein Deficiency.

SEPSECS SECISBP2

9.37e-06362234884733
Pubmed

Epithelial permeability alterations in an in vitro air-liquid interface model of allergic fungal rhinosinusitis.

OCLN CLDN2

9.37e-06362222927233
Pubmed

Uncontrolled C3 activation causes membranoproliferative glomerulonephritis in mice deficient in complement factor H.

CFH CFHR4

9.37e-06362212091909
Pubmed

Functional properties of complement factor H-related proteins FHR-3 and FHR-4: binding to the C3d region of C3b and differential regulation by heparin.

CFHR4 CFHR3

9.37e-06362210622723
Pubmed

Borrelia burgdorferi binding of host complement regulator factor H is not required for efficient mammalian infection.

CFH CFHR4

9.37e-06362217420242
Pubmed

Immunoglobulin genes of the kappa light chain type from two human lymphoid cell lines are closely related.

IGKV1-39 IGKV1D-39

9.37e-0636226091049
Pubmed

Complement Regulatory Protein Factor H Is a Soluble Prion Receptor That Potentiates Peripheral Prion Pathogenesis.

CFH CFHR4

9.37e-06362229070671
Pubmed

Altered expression patterns of complement factor H and miR-146a genes in acute-chronic phases in experimental autoimmune encephalomyelitis mouse.

CFH CFHR4

9.37e-06362230972735
Pubmed

Retinal Basal Laminar Deposits in Complement fH/fP Mouse Model of Dense Deposit Disease.

CFH CFHR4

9.37e-06362230025090
Pubmed

Tight junction proteins in gallbladder epithelium: different expression in acute acalculous and calculous cholecystitis.

OCLN CLDN2

9.37e-06362217283368
Pubmed

Comparison of surface recognition and C3b binding properties of mouse and human complement factor H.

CFH CFHR4

9.37e-06362216023208
Pubmed

Location of theSas-1 locus on mouse chromosome 1.

CFH CFHR4

9.37e-06362221302086
Pubmed

Loss of properdin exacerbates C3 glomerulopathy resulting from factor H deficiency.

CFH CFHR4

9.37e-06362223184055
Pubmed

A single gene product, claudin-1 or -2, reconstitutes tight junction strands and recruits occludin in fibroblasts.

OCLN CLDN2

9.37e-0636229786950
Pubmed

Variants in Complement Factor H and Complement Factor H-Related Protein Genes, CFHR3 and CFHR1, Affect Complement Activation in IgA Nephropathy.

CFH CFHR3

9.37e-06362225205734
Cytoband1q32

CFH CFHR4 CFHR3

4.13e-05496231q32
CytobandEnsembl 112 genes in cytogenetic band chr1q31

CFH CFHR4 CFHR3

1.48e-0475623chr1q31
GeneFamilyComplement system|Sushi domain containing

CFH CFHR4 CFHR3

5.83e-0536383492
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

CFH CFHR4 CFHR3

2.32e-04573831179
GeneFamilyFibronectin type III domain containing

L1CAM ROS1 USH2A

4.57e-03160383555
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

PLEKHG1 PLEKHG3

8.48e-0366382722
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

PLEKHG1 APPL2 PLEKHG3

9.17e-03206383682
CoexpressionAtlasFacebaseRNAseq_e10.5_Olfactory Pit_top-relative-expression-ranked_1000_k-means-cluster#5

CLSTN3 ZFHX4 NRK SLC26A5 P4HA3 RBM47 EPAS1

1.11e-05276597Facebase_RNAseq_e10.5_Olfactory Pit_1000_K5
CoexpressionAtlasFacebaseRNAseq_e8.5_Non-Floor Plate Neural Epithelium_top-relative-expression-ranked_1000_k-means-cluster#4

CLSTN3 ZFHX4 NRK MAPKAPK3 TENT5C P4HA3 EPAS1

1.83e-05298597Facebase_RNAseq_e8.5_Non-Floor Plate Neural Epithelium_1000_K4
CoexpressionAtlasdev lower uro neuro_e15.5_PelvicGanglion_Sox10_k-means-cluster#1_top-relative-expression-ranked_1000

NRXN1 NRK L1CAM P4HA3 PGAP4 KIF5A

2.60e-05211596gudmap_dev lower uro neuro_e15.5_PelvicGanglion_Sox10_k1_1000
CoexpressionAtlasFacebaseRNAseq_e9.5_Olfactory Placode_top-relative-expression-ranked_1000_k-means-cluster#5

CLSTN3 ZFHX4 NRK P4HA3 RBM47 EPAS1

5.86e-05244596Facebase_RNAseq_e9.5_Olfactory Placode_1000_K5
CoexpressionAtlasFacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_500_k-means-cluster#3

CLSTN3 ZFHX4 NRK TENT5C P4HA3 EPAS1

6.56e-05249596Facebase_RNAseq_e8.5_Paraxial Mesoderm_500_K3
CoexpressionAtlasFacebaseRNAseq_e9.5_Olfactory Placode_top-relative-expression-ranked_1000

CLSTN3 ZFHX4 NRXN1 ACRBP PLEKHG3 NRK GAS1 TENT5C P4HA3 RBM47 EPAS1

6.56e-059735911Facebase_RNAseq_e9.5_Olfactory Placode_1000
CoexpressionAtlasFacebaseRNAseq_e9.5_Maxillary Arch_top-relative-expression-ranked_1000_k-means-cluster#1

CLSTN3 ZFHX4 NRK MAPKAPK3 P4HA3 RBM47 EPAS1

7.34e-05371597Facebase_RNAseq_e9.5_Maxillary Arch_1000_K1
CoexpressionAtlasFacebaseRNAseq_e9.5_Facial Mesenchyne_top-relative-expression-ranked_1000_k-means-cluster#3

CLSTN3 ZFHX4 NRK MAPKAPK3 SLC26A5 P4HA3 EPAS1

9.10e-05384597Facebase_RNAseq_e9.5_Facial Mesenchyne_1000_K3
CoexpressionAtlasFacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_1000

CLSTN3 GPR50 ZFHX4 NRXN1 TAS1R3 NRK MAPKAPK3 TENT5C P4HA3 EPAS1

3.02e-049675910Facebase_RNAseq_e8.5_Paraxial Mesoderm_1000
CoexpressionAtlasFacebaseRNAseq_e9.5_Maxillary Arch_top-relative-expression-ranked_1000

CLSTN3 GPR50 ZFHX4 NRXN1 NRK MAPKAPK3 TENT5C P4HA3 RBM47 EPAS1

3.02e-049675910Facebase_RNAseq_e9.5_Maxillary Arch_1000
CoexpressionAtlasFacebaseRNAseq_e9.5_Facial Mesenchyne_top-relative-expression-ranked_1000

CLSTN3 GPR50 ZFHX4 NRXN1 NRK MAPKAPK3 SLC26A5 TENT5C P4HA3 EPAS1

3.04e-049685910Facebase_RNAseq_e9.5_Facial Mesenchyne_1000
CoexpressionAtlasFacebaseRNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_1000

CLSTN3 GPR50 ZFHX4 NRXN1 NRK MAPKAPK3 TENT5C P4HA3 RBM47 EPAS1

3.14e-049725910Facebase_RNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_1000
CoexpressionAtlasFacebaseRNAseq_e8.5_Non-Floor Plate Neural Epithelium_top-relative-expression-ranked_1000

CLSTN3 GPR50 ZFHX4 NRXN1 PLEKHG3 NRK MAPKAPK3 TENT5C P4HA3 EPAS1

3.25e-049765910Facebase_RNAseq_e8.5_Non-Floor Plate Neural Epithelium_1000
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZFHX4 NRXN1 NRK ROS1 KIF5A USH2A

2.19e-071846262cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZFHX4 NRXN1 NRK ROS1 KIF5A USH2A

2.19e-07184626ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZFHX4 NRXN1 NRK ROS1 KIF5A USH2A

2.19e-071846262b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellPBMC-Control-Lymphocyte-B-B_cell-B_memory-B_memory-6|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IGKV1-39 NRXN1 MS4A1 TAS1R3 IGKV1D-39

2.07e-061496252cd860b96ed4be4d26844085d464961c1418054a
ToppCellBAL-Mild-Lymphocyte-B|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IGKV1-39 PLEKHG1 MS4A1 TAS1R3 IGKV1D-39

3.84e-06169625307571e57c3bfdf15f0fe1a8b36585e8e4f8a207
ToppCell5'-Adult-Distal_Rectal-Hematopoietic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IGKV1-39 TENT5C IGKV1D-39 CPVL MFSD1

4.30e-06173625b335ca2a247156eba821943b2b9fc9922230b409
ToppCellBAL-Mild-Lymphocyte-B|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

IGKV1-39 PLEKHG1 MS4A1 TAS1R3 IGKV1D-39

5.36e-06181625700adfb41e4e377530f0dd31be89e12f109f3469
ToppCellMild_COVID-19-B_cell|Mild_COVID-19 / Disease group,lineage and cell class (2021.01.30)

IGKV1-39 PLEKHG1 MS4A1 TAS1R3 IGKV1D-39

5.65e-06183625dea119e2988e954475f557f0bbe12556a83e81a4
ToppCellB_cell_maturation-plasma|World / Lineage and Cell class

IGKV1-39 PSAT1 TAS1R3 TENT5C IGKV1D-39

5.65e-061836250c3cb61912df05f1beba1004540770ef1a4de786
ToppCellwk_15-18-Hematologic_Lymphocytic-B-CD5+_CCL22-_mature_B|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

IGKV1-39 PLEKHG1 MS4A1 TENT5C IGKV1D-39

5.80e-0618462518aa9c43b79d12c9e420dfd9822745c022be6789
ToppCellSevere_COVID-19-B_cell|Severe_COVID-19 / Disease group,lineage and cell class (2021.01.30)

IGKV1-39 PSAT1 MS4A1 TENT5C IGKV1D-39

6.61e-0618962559ce8f15f413557d2059ee6b53ba5957b864cb8e
ToppCellBAL-Severe-Lymphocyte-B|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

IGKV1-39 PSAT1 MS4A1 TENT5C IGKV1D-39

6.78e-06190625d55b9f9b82bd2b2e1ea2446813fce04f04a1dcdf
ToppCellcellseq2-Immune-Lymphocytic_B-Lymphocytic_B|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

IGKV1-39 MS4A1 TAS1R3 TENT5C IGKV1D-39

6.96e-0619162517746a32f723c078aba1f7e320b0e3f1ab8bf5c6
ToppCellcellseq2-Immune-Lymphocytic_B|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

IGKV1-39 MS4A1 TAS1R3 TENT5C IGKV1D-39

6.96e-06191625c2c450df810f83163987cd0f7ed9b50025cd3de1
ToppCell5'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-Differentiating_glia|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PSAT1 NRXN1 L1CAM PGAP4 KIF5A

7.32e-06193625d5930f7bd9b299f792212d40a3272a37adf64a82
ToppCellTracheal-10x5prime-Stromal-Schwann|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

NRXN1 L1CAM TTYH2 KIF5A TMEM215

7.89e-06196625b6226163d9fc93ecfff2115bb74408303a000490
ToppCellParenchymal-10x5prime-Stromal-Mesofibroblastic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CFH ZFHX4 NRK GAS1 WNK4

8.08e-0619762588a86286b9c3ea3b076d7464faec42d0392ee7f8
ToppCellParenchymal-10x5prime-Stromal-Mesofibroblastic-Mesothelia|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CFH ZFHX4 NRK GAS1 WNK4

8.08e-061976252773d2eb5f232a7e49da116efffcb6bf5eb90810
ToppCellSigmoid-(5)_Dendritic_cell-(51)_cDC1|Sigmoid / shred on region, Cell_type, and subtype

STAC3 TTYH2 CPVL TGM5 MGAM2

8.70e-062006254ce0a2238c90622e41fd86ac4b7d82adf4af2c3b
ToppCellSigmoid-Dendritic_cell-cDC1|Sigmoid / Region, Cell class and subclass

STAC3 TTYH2 CPVL TGM5 MGAM2

8.70e-062006253523ec986e8c9e176e08836c974b1de8b56d8b16
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c4-CD14-CD16|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

ANKAR STAC3 TLR7 CPVL

2.23e-051186247e6cb77fa9154f2da985c455bb6a24d6029cc8d6
ToppCellLPS-antiTNF-Epithelial_alveolar-Mes-Like-Differentiating_AT1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ZFHX4 SLC26A5 P4HA3 CFAP43

3.07e-051286242cf0384240a4a663869cf6b27d954236f6214a9a
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Dendritic-conventional_dendritic_cell-DC_c1-CLEC9A|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SEPSECS ACRBP ELOVL1 USH2A

3.36e-051316241823cab28fab40486247ca92104267b1e370bdc1
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANKAR SLC26A5 ROS1 USH2A

4.99e-0514562496712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCellLPS-IL1RA-Myeloid-Dendritic_cells-Monocytes-Macrophages|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ACRBP STAC3 TLR7 CPVL

5.55e-05149624a464c0fd54e3c9e1d40d95b49489cb9371dd7c24
ToppCellsaliva-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CLSTN3 MS4A1 ACRBP WNK4

7.14e-051596241dde4d19cc0fde7ebbccb4c31bb845a92206021b
ToppCell368C-Lymphocytic-Plasma_cell-|368C / Donor, Lineage, Cell class and subclass (all cells)

IGKV1-39 TAS1R3 TENT5C IGKV1D-39

7.68e-05162624c21a54310b239d999bbc9d8fb5e8fda16e0bc336
ToppCell368C-Lymphocytic-Plasma_cell|368C / Donor, Lineage, Cell class and subclass (all cells)

IGKV1-39 TAS1R3 TENT5C IGKV1D-39

7.68e-05162624f945688815229c8386cbcbf46deee7df316fa8d3
ToppCellfacs-Trachea-18m-Hematologic-lymphocytic-B_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MS4A1 TENT5C SECISBP2 RBM47

8.05e-051646244274a4f225cabf61f0fe27d8ea162b4eba612f87
ToppCellfacs-Trachea-18m-Hematologic-lymphocytic-B_cell-B_cell_of_the_trachea|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MS4A1 TENT5C SECISBP2 RBM47

8.05e-05164624d62143450f59097ad4b34603a6257f897a769ead
ToppCell367C-Myeloid-Monocyte-CD16+_Monocyte|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

IGKV1-39 MS4A1 MAPKAPK3 P4HA3

8.05e-051646241aff83fc73b4e41e6f0d4b04dbca153bcc7a3518
ToppCellfacs-Lung-Endomucin-3m-Myeloid-Myeloid_Dendritic_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PSAT1 ACRBP PLEKHG3 L1CAM

8.44e-05166624a2ce44702a0cd5fa5872cac3302d3c451205feef
ToppCellfacs-Lung-Endomucin-3m-Myeloid-myeloid_dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PSAT1 ACRBP PLEKHG3 L1CAM

8.44e-051666240f641302a6b71c4badaaf20f51162bfc2386b167
ToppCellICU-NoSEP-Lymphocyte-T_NK-MAIT|ICU-NoSEP / Disease, Lineage and Cell Type

PSAT1 CDC42BPA ANKAR OCLN

8.44e-05166624d3fa2e42497201f1ca57f4f977fbaa0def950033
ToppCell367C-Lymphocytic-NK_cells-NK_cell_E|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

HOXA6 GAS1 P4HA3 RBM47

8.64e-05167624b5d15773be32cd277125fd3b4056a8fefaefa5ec
ToppCellBAL-Mild-Lymphocyte-B-B_cell-B_cell-B_activate-7|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IGKV1-39 PLEKHG1 MS4A1 IGKV1D-39

9.25e-05170624ee2ee67d90ae4596de8ccd620e37c82cf51651d4
ToppCellBAL-Mild-Lymphocyte-B-B_cell-B_cell|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IGKV1-39 PLEKHG1 MS4A1 IGKV1D-39

9.25e-05170624d7ca0c6ce5d2b7de99346f87e07aa7fe728fa08a
ToppCellControl-Lymphoid-B_Plasma|World / Disease state, Lineage and Cell class

IGKV1-39 TAS1R3 TENT5C IGKV1D-39

9.25e-05170624fb05f49b7113470995b3c16683c54dc1a660b73a
ToppCellBAL-Mild-Lymphocyte-B-B_cell|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IGKV1-39 PLEKHG1 MS4A1 IGKV1D-39

9.25e-0517062452787f6d529c285d9f0c04cc022710ead5b89b3f
ToppCell367C-Myeloid-Monocyte-CD16+_Monocyte|Monocyte / Donor, Lineage, Cell class and subclass (all cells)

IGKV1-39 MS4A1 MAPKAPK3 P4HA3

9.68e-05172624fb8ab2576b5c38db63573a3bf46b8d9d634c4999
ToppCellPlasma_cells|World / lung cells shred on cell class, cell subclass, sample id

IGKV1-39 TAS1R3 TENT5C IGKV1D-39

9.90e-0517362452a387e2a4694af61a9223a4c2ecf4e6f762c064
ToppCellAT1_cells-Donor_07|World / lung cells shred on cell class, cell subclass, sample id

PSAT1 NRK SLC26A5 PGAP4

9.90e-05173624b29816427428c7053017477f59b828bf1357f3b2
ToppCellwk_15-18-Hematologic_Lymphocytic-B-CD5+_CCL22+_mature_B|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

IGKV1-39 MS4A1 IGKV1D-39 HSF5

1.03e-04175624fa53ea81ad943a2cd266114829135cbcbcf2f634
ToppCellwk_08-11-Mesenchymal-Chondrocyte|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

CFH PLEKHG1 NRK WNK4

1.06e-041766241af28b701c4598ce761f85adbd5d79e4918d265a
ToppCellwk_15-18-Epithelial-PNS-Schwann_precursor|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

PSAT1 NRXN1 L1CAM PGAP4

1.08e-041776245357359e6c2161a37f39a6b3b78449f5cbc327d1
ToppCell(2)_Plasma_cells|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

IGKV1-39 TAS1R3 TENT5C IGKV1D-39

1.08e-04177624ed3c936bb69f9bc7291b4f6cde1d204078117c48
ToppCell-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

IGKV1-39 MS4A1 TENT5C IGKV1D-39

1.08e-04177624ae2d2e138946535596fa30a55207f261cafda461
ToppCellPBMC-Convalescent-Lymphocyte-B-B_cell-B_naive-B_naive-8|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MS4A1 ANKAR TLR7 KIF5A

1.08e-04177624066e7500e7bdde88a7914f50a4661d8adf6db925
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IGKV1-39 MS4A1 TENT5C IGKV1D-39

1.10e-04178624107dae8b00c4257697a63700e72bb434cdb8406f
ToppCellfacs-Marrow-Granulocytes-3m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GAS1 CFAP43 OCLN DMRT1

1.10e-041786246d9ecfaeb50d562899380de379ebf7b99fd8adc9
ToppCellfacs-Marrow-Granulocytes-3m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GAS1 CFAP43 OCLN DMRT1

1.10e-04178624d3f518cd75b02e85d45cbb9b2eff30f0272512a8
ToppCellcellseq-Immune-Lymphocytic_B-Lymphocytic_B|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

IGKV1-39 MS4A1 TENT5C IGKV1D-39

1.15e-04180624cd04d7bf92986a5b8a0193c9b92ec47da3929bac
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells-Plasma_cells_L.1.7.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IGKV1-39 TAS1R3 TENT5C IGKV1D-39

1.15e-04180624e3877f6ef5f54ff689058b4c996ab1851822f871
ToppCellcellseq-Immune-Lymphocytic_B|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

IGKV1-39 MS4A1 TENT5C IGKV1D-39

1.15e-04180624663a800ab70e7ab7d13183417f9c1ed36907aa5e
ToppCellPBMC-Convalescent-Lymphocyte-B-B_cell-B_naive-B_naive-2|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MS4A1 ANKAR TLR7 KIF5A

1.18e-0418162475035a3211e524bb659b82e6979f7d3a3121ae70
ToppCelldroplet-Heart-4Chambers-18m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRXN1 L1CAM TTYH2 P4HA3

1.20e-041826246fdaf3c8c3952a8f14dd7288e523ed58eb1d3517
ToppCellChildren_(3_yrs)-Epithelial-club_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

CFH PLEKHG1 TENT5C OCLN

1.20e-04182624215c303df42f13597b2c7a95cb157c6bc7aca9a1
ToppCell10x5'-Lung-Lymphocytic_B|Lung / Manually curated celltypes from each tissue

IGKV1-39 PLEKHG1 MS4A1 IGKV1D-39

1.20e-04182624310f94437d197eaaaf6e30e68063b33e94befe77
ToppCellPBMC-Control-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-6|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PLEKHG1 MS4A1 TAS1R3 IGKV1D-39

1.23e-0418362482fe14fc7039415de41bdfd615a1380bed99f560
ToppCelldroplet-Lung-nan-3m-Mesenchymal-Adventitial_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH NRK GAS1 TMEM215

1.23e-04183624a253ad65673fce6cb453e709cb235ce7cbfa18b7
ToppCellMild-Lymphoid-B|Mild / Condition, Lineage, Cell class and cell subclass

IGKV1-39 PLEKHG1 MS4A1 IGKV1D-39

1.23e-041836249b64d2d143525e6f48a191facfd101462ff36324
ToppCelldroplet-Lung-nan-3m-Mesenchymal-adventitial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH NRK GAS1 TMEM215

1.23e-04183624ddc45fb591ba0ce3fa05c08051d58286a89ef835
ToppCellMild-Lymphoid-B-|Mild / Condition, Lineage, Cell class and cell subclass

IGKV1-39 PLEKHG1 MS4A1 IGKV1D-39

1.23e-04183624b5740f05a4dcdbbf24f7bf7a3f57ac01a5e75f60
ToppCell3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells-Plasma_cells_L.1.7.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IGKV1-39 TAS1R3 TENT5C IGKV1D-39

1.23e-04183624cf5c98f451a568308c52da5c926543dd4836c6b2
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-4|TCGA-Pancreas / Sample_Type by Project: Shred V9

ZFHX4 NRK TLR7 TMEM215

1.25e-0418462467164bb6bcae7322cb89b585c7aa10bce35b0ecd
ToppCellBAL-Mild-Lymphocyte-B-B_cell-B_cell|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

IGKV1-39 PLEKHG1 MS4A1 IGKV1D-39

1.25e-041846243f8a359e40bebe58545f708682e5e5d1b70cf5cb
ToppCellBAL-Mild-Lymphocyte-B-B_cell-B_cell-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

IGKV1-39 PLEKHG1 MS4A1 IGKV1D-39

1.25e-0418462464bede8db709fd32f40c03265b96f0b12155bb8a
ToppCellBAL-Mild-Lymphocyte-B-B_cell|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

IGKV1-39 PLEKHG1 MS4A1 IGKV1D-39

1.28e-04185624609080adb2cfb105bb7b8efb617553833299f371
ToppCell3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IGKV1-39 TAS1R3 TENT5C IGKV1D-39

1.28e-041856246ec009e48e50471c28e914c402f500e56a88f8f2
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLEKHG1 GAS1 OCLN WNK4

1.28e-04185624af86e75096c1812ae27a78405355957ee8043d84
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_B-Plasma_Cell-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

IGKV1-39 TAS1R3 TENT5C IGKV1D-39

1.28e-041856240fff2608f507e019ebb69c27e58fd5be3b049bef
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_B-Plasma_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

IGKV1-39 TAS1R3 TENT5C IGKV1D-39

1.28e-0418562479edc1eeb7b5b9123961ac3ecf398ee68d9dddb9
ToppCell3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IGKV1-39 TAS1R3 TENT5C IGKV1D-39

1.28e-04185624f49ad6401b2abd089e30eba245b11b5031ea2318
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IGKV1-39 TAS1R3 TENT5C IGKV1D-39

1.28e-0418562408bc817908076734d66f2805cb954141f2cc5a18
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IGKV1-39 TAS1R3 TENT5C IGKV1D-39

1.28e-041856241704a12153a9b107bf03ecccd1a036cf61334d7a
ToppCell10x5'-Liver-Lymphocytic_B_plasma|Liver / Manually curated celltypes from each tissue

IGKV1-39 PSAT1 TAS1R3 IGKV1D-39

1.31e-04186624a2c7430781f432c9c90ac4d620f4518ff767a223
ToppCellcellseq-Mesenchymal-Fibroblastic-Fibroblastic_1-Mesothelial|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CFH ZFHX4 NRK GAS1

1.31e-041866247812ed80d2378aca9957ef22fc3c8fb7fb58434b
ToppCellMild_COVID-19-B_cell-B_cell|Mild_COVID-19 / Disease group,lineage and cell class (2021.01.30)

IGKV1-39 PLEKHG1 MS4A1 IGKV1D-39

1.31e-04186624855a5a00ba2aa1b5c63b8db56d026ddecc546050
ToppCellAdult-Epithelial-club_cell-D231|Adult / Lineage, Cell type, age group and donor

CFH PLEKHG1 TENT5C OCLN

1.34e-04187624ee59d7d3de5879738ff0b9c3ea5e4847fb48cb86
ToppCell3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IGKV1-39 MS4A1 TENT5C IGKV1D-39

1.34e-041876248089ae6ee59533a090fe0b19bdd057fba8fa11de
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CFH ZFHX4 NRXN1 GAS1

1.36e-04188624c32d023a69b6da79687ff8fa7485e7499db57046
ToppCellsevere_COVID-19-Plasmablast|World / disease group, cell group and cell class (v2)

IGKV1-39 PSAT1 TAS1R3 IGKV1D-39

1.36e-0418862425ca19af4ac419a0f5026a6ccbd8b554b268a6f3
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CFH ZFHX4 NRXN1 GAS1

1.36e-041886241cd5a4d744bd3777246958ea5eb94388a5cbad81
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRXN1 MS4A1 TTYH2 TMEM215

1.36e-04188624a91443aa8fa8fa87f7501c59219daa0305bd0bbf
ToppCellcellseq2-Immune-Lymphocytic_B-Lymphocytic_B-Plasma|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

IGKV1-39 TAS1R3 TENT5C IGKV1D-39

1.36e-0418862433360f1c30315d9772731c9067834dc059172b79
ToppCellBAL-Severe-Lymphocyte-B-Plasmablast-Plasmablast-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

IGKV1-39 PSAT1 TENT5C IGKV1D-39

1.39e-04189624b0fcbe13a91a4b8dfa507b7a484f45477ef31609
ToppCelldroplet-Heart-nan-3m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH NRK OCLN WNK4

1.39e-041896248e583ec4df0f5b79ce5211cc99ecd8616d180bde
ToppCellBAL-Severe-Lymphocyte-B-Plasmablast|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

IGKV1-39 PSAT1 TENT5C IGKV1D-39

1.39e-04189624d5d25f4151ea96e2d4b3a0e0910e7ff995eaf752
ToppCellControl-B_intermediate-6|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

MS4A1 TAS1R3 STAC3 ADAM32

1.39e-0418962411cb9a16f1de8f60af2073ed7ea6d4f41c02f299
ToppCellSevere_COVID-19-B_cell-Plasmablast|Severe_COVID-19 / Disease group,lineage and cell class (2021.01.30)

IGKV1-39 PSAT1 TENT5C IGKV1D-39

1.39e-04189624d7bfefc8c35374c5288807349a76dbb10e84c52b
ToppCell10x_3'_v3-bone_marrow_(10x_3'_v3)-lymphocytic-B_lymphocytic-plasma_cell|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

IGKV1-39 TAS1R3 TENT5C IGKV1D-39

1.39e-041896245a42be62552d912d0abf68f00d75ac80bbd69f2c
ToppCellBAL-Severe-Lymphocyte-B-Plasmablast-Plasmablast|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

IGKV1-39 PSAT1 TENT5C IGKV1D-39

1.39e-041896240f0607642eecc66222d23afe6d77b6872343cb8e
ToppCellwk_15-18-Hematologic_Lymphocytic-B-Immature_B|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

IGKV1-39 PLEKHG1 MS4A1 IGKV1D-39

1.39e-041896245776f842b3047d21ccdc44db884bfd210823c7da
ToppCelldroplet-Heart-nan-3m-Endothelial-endocardial_endothelial_cells|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH NRK OCLN WNK4

1.39e-04189624fb2253b8463d08b3d28e952a31a23dea2c2d986b
ToppCellwk_15-18-Hematologic_Lymphocytic-B-CD5-_Mature_B|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

IGKV1-39 PLEKHG1 MS4A1 IGKV1D-39

1.42e-04190624ade43d1d1f8909b8526a23152acf3c26f160f836
ToppCellBAL-Severe-Lymphocyte-B|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IGKV1-39 PSAT1 TENT5C IGKV1D-39

1.42e-04190624e82fefea5ac03470d10463832d3efd2380895860
ToppCellBAL-Severe-Lymphocyte-B-Plasmablast|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IGKV1-39 PSAT1 TENT5C IGKV1D-39

1.42e-041906249560722facaf3516936fcbc2a900a405fd85e5d0
ToppCellBAL-Severe-Lymphocyte-B-Plasmablast-Plasmablast|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IGKV1-39 PSAT1 TENT5C IGKV1D-39

1.42e-041906247fbaf46bf24d46543047582f0d262f3523e28eb4
ToppCellChildren_(3_yrs)-Epithelial-club_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

CFH PLEKHG1 TENT5C OCLN

1.45e-0419162423776c7302cead3881b39127398f3b3e0d27885e
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRXN1 MS4A1 TTYH2 TMEM215

1.45e-041916243387b95a3f2445c672d407922fdce3a91eabaef8
Drug(2S)-N-[4-(aminomethyl)-1,1-dioxothian-4-yl]-2-[1-(benzenesulfonamido)ethylideneamino]-3-(1-methylcyclopentyl)propanamide

CFH CFHR3

6.38e-062582CID011840931
DiseaseNADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial measurement

CFH CFHR4 CFHR3

2.73e-084573EFO_0803292
DiseaseAtypical hemolytic-uremic syndrome

CFH CFHR4 CFHR3

5.69e-079573cv:C2931788
DiseaseHemolytic-uremic syndrome

CFH CFHR4 CFHR3

5.69e-079573cv:C0019061
Diseasec3d:C3 ratio

CFH CFHR4

3.67e-062572EFO_0008543
Diseaseendoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase measurement

CFH CFHR3

1.10e-053572EFO_0801568
Diseaseanaphase-promoting complex subunit 7 measurement

CFH CFHR3

1.10e-053572EFO_0801381
DiseaseHEMOLYTIC UREMIC SYNDROME, ATYPICAL, SUSCEPTIBILITY TO, 1

CFH CFHR3

1.10e-053572C2749604
DiseaseHEMOLYTIC UREMIC SYNDROME, ATYPICAL, SUSCEPTIBILITY TO, 1

CFH CFHR3

1.10e-053572235400
Diseasecalnexin measurement

CFH CFHR4

1.10e-053572EFO_0801444
Diseasecomplement factor H-related protein 4A measurement

CFH CFHR4

1.10e-053572EFO_0600057
DiseaseHemolytic uremic syndrome, atypical, susceptibility to, 1

CFH CFHR3

1.10e-053572cv:C2749604
Diseasehistone-lysine N-methyltransferase 2D measurement

CFH CFHR4

1.10e-053572EFO_0801683
DiseaseMeningococcal Infections

CFH CFHR3

2.19e-054572C0025303
Diseasekallikrein-5 measurement

CFH CFHR4

2.19e-054572EFO_0020515
DiseaseAutism Spectrum Disorders

GPR50 NRXN1 ANKRD11 USH2A

2.25e-0585574C1510586
DiseaseAge related macular degeneration

CFH CFHR4 CFHR3

2.67e-0530573C0242383
DiseaseComplement deficiency disease

CFH CFHR4 CFHR3

3.58e-0533573C0272242
Diseasecomplement C1s subcomponent measurement

CFH CFHR4

5.47e-056572EFO_0008091
Diseasecomplement factor H measurement

CFH RBM47 CFHR4

6.92e-0541573EFO_0008097
Diseaseatypical hemolytic-uremic syndrome (is_implicated_in)

CFH CFHR3

1.02e-048572DOID:0080301 (is_implicated_in)
Diseaseleukocyte immunoglobulin-like receptor subfamily A member 5 measurement

CFH CFHR4

1.31e-049572EFO_0801766
DiseaseAtypical Hemolytic Uremic Syndrome

CFH CFHR3

1.63e-0410572C2931788
Diseasehemopexin measurement

CFH CFHR4

1.99e-0411572EFO_0008149
Diseasecomplement factor H-related protein 3 measurement

CFH USH2A CFHR4 CFHR3

3.24e-04169574EFO_0600056
DiseaseSpastic Paraplegia, Hereditary

L1CAM KIF5A

3.29e-0414572C0037773
DiseaseAge-related macular degeneration

CFH CFHR3

5.50e-0418572cv:C0242383
Diseasecoagulation factor measurement

CFH CFHR4

6.81e-0420572EFO_0004634
DiseaseCOVID-19 (is_implicated_in)

CFH TLR7

7.52e-0421572DOID:0080600 (is_implicated_in)
Diseasetemperament and character inventory

SEPSECS NRXN1

9.85e-0424572EFO_0004825
Diseaseazoospermia (implicated_via_orthology)

CDC42BPA YIPF7

1.25e-0327572DOID:14227 (implicated_via_orthology)
Diseasecomplement factor H-related protein 2 measurement

CFH CFHR4

1.44e-0329572EFO_0600055

Protein segments in the cluster

PeptideGeneStartEntry
PQCYATQYQDYSLSS

EPAS1

801

Q99814
QIYGFCSQVPYICSY

CFAP43

601

Q8NDM7
DYCITPYAYNQDQHS

ERVK13-1

381

Q9NX77
QAPQCYAEYVTYTGS

ANKRD11

2461

Q6UB99
QYSQICYYEILTPNT

CLSTN3

176

Q9BQT9
LSLPCQIGSQVYYYN

C2orf78

201

A6NCI8
YIQYPNYCSFKSQQC

ACRBP

481

Q8NEB7
TYSSDIQTQCYYQGN

ADAM32

86

Q8TC27
SVYAPASSVEYQCQN

CFH

1126

P08603
NSPSTQYCYSIQSLF

MS4A1

176

P11836
SSSYSNEQQLCPYAA

MKRN2

161

Q9H000
QQPSYVYSCDPYTLA

RBM47

341

A0AV96
NQYQACYPSSSFGVT

EYA3

206

Q99504
QIYALCNQFYTPAAT

OCLN

211

Q16625
YCSYETNSNAYLLLQ

P4HA3

321

Q7Z4N8
CQICYLNYPNSYFTG

ARIH1

186

Q9Y4X5
YDQSSSCQLPPAYYD

ANKAR

126

Q7Z5J8
AYDSYVAICNPLQYS

OR52E2

121

Q8NGJ4
QPEDFATYYCQQSYS

IGKV1D-39

101

P04432
TYTSPCFYQQSNSVL

HOXA6

51

P31267
QNALQTPCYTPYYVA

MAPKAPK3

196

Q16644
CYYDTIPNYVASDIQ

MGAM2

946

Q2M2H8
YDPRTYTCIFNYLNN

GPR50

171

Q13585
DPSYFQNVTGCSNYY

CPVL

301

Q9H3G5
ASLSPQYVSYNQSSY

L1CAM

1061

P32004
SYFCYDNPAALQTQV

MFSD1

56

Q9H3U5
CSYAYNQYAEACAPV

GAS1

61

P54826
YVYCLESSLQTYNPD

PGAP4

191

Q9BRR3
YFCYDLSQNPIQSSS

NRXN1

291

Q9ULB1
YTSQYSNSLNPFYTL

GUCA1ANB

81

X6R8D5
PYYELQGSNYVTCSN

CFHR3

241

Q02985
LSSLQYYCALNALQY

APPL2

176

Q8NEU8
ISQYYFMSSCNYQYP

ELOVL1

216

Q9BW60
GQSYSYYCDQNFVTP

CFHR4

296

Q92496
VYVPQSRVEYQCQSY

CFHR4

476

Q92496
QCQSYYELQGSNYVT

CFHR4

486

Q92496
RSNYYDAYQAQPLAT

CLDN2

191

P57739
PECISYTNSLFQNYQ

KIF5A

941

Q12840
QPEDFATYYCQQSYS

IGKV1-39

101

P01597
NSCQPQSYLVRNYHY

KRTAP24-1

196

Q3LI83
RTCYPLSYFSYGNQT

KRTAP25-1

41

Q3LHN0
QCGDYYSALYTVPTQ

SEC24B

86

O95487
YYNNLYNCPQYSMAL

DMRT1

221

Q9Y5R6
NNNYYEAPSCPRASY

NRK

981

Q7Z2Y5
KYSNYTPSAQYSQAY

HSF5

291

Q4G112
YSQAYYPTAVLQCCS

HSF5

301

Q4G112
LQPYSQYNFSLVACT

USH2A

4411

O75445
TQYCNNYPNSVAALT

PLEKHG3

181

A1L390
NAPIYYANSDLYSNA

SLC26A5

541

P58743
NLNPDASYVYYCANE

PSAT1

141

Q9Y617
YLYNQPSCYRGFQTV

SECISBP2

111

Q96T21
NPSSCCYNAPYLSVY

CDC42BPA

1451

Q5VT25
CYNAPYLSVYSENAV

CDC42BPA

1456

Q5VT25
TNVTCYYQPAPYVSD

TENT5C

351

Q5VWP2
TSCYYNSTLTNQKLY

RNASE13

121

Q5GAN3
FYQCPYCNYNSRDQS

ZFHX4

1171

Q86UP3
AAYCNYTQYQPRVLA

TAS1R3

126

Q7RTX0
QNSPYDRYCCYINQI

TMEM215

211

Q68D42
YYLYCSQSGSSPFQQ

TTYH2

296

Q9BSA4
AYVCNITNLQPYTSY

ROS1

1711

P08922
PCKISYSQYSQYLST

TGM5

576

O43548
QNCYYRNPCYVSYSI

TLR7

181

Q9NYK1
TCYVQGASPCQSYYV

XP32

131

Q5T750
TNNYPCAYLNAASAI

SEPSECS

426

Q9HD40
YTQYCTNYPRSVAVL

PLEKHG1

201

Q9ULL1
FQPASNSDYYSQSPY

YIPF7

91

Q8N8F6
AYSSPLYSNQQYACV

STAC3

151

Q96MF2
SEYPYSECQNAAQIY

WNK4

371

Q96J92