Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessprotein secretion

PORCN TRPM4 RHBDD3 NEO1 EPHA5

1.59e-04480235GO:0009306
GeneOntologyBiologicalProcessestablishment of protein localization to extracellular region

PORCN TRPM4 RHBDD3 NEO1 EPHA5

1.64e-04483235GO:0035592
GeneOntologyBiologicalProcessprotein localization to extracellular region

PORCN TRPM4 RHBDD3 NEO1 EPHA5

1.75e-04490235GO:0071692
GeneOntologyBiologicalProcessaxon guidance

NEO1 GDF7 EPHA5 ROBO3

2.57e-04285234GO:0007411
GeneOntologyBiologicalProcessneuron projection guidance

NEO1 GDF7 EPHA5 ROBO3

2.60e-04286234GO:0097485
Domainfn3

SPEG NEO1 EPHA5 ROBO3

4.25e-05162234PF00041
DomainFN3

SPEG NEO1 EPHA5 ROBO3

7.12e-05185234SM00060
DomainI-set

SPEG NEO1 ROBO3 CEACAM7

7.90e-05190234PF07679
DomainIg_I-set

SPEG NEO1 ROBO3 CEACAM7

7.90e-05190234IPR013098
DomainFN3

SPEG NEO1 EPHA5 ROBO3

9.45e-05199234PS50853
DomainFN3_dom

SPEG NEO1 EPHA5 ROBO3

1.14e-04209234IPR003961
Domain-

SPEG NEO1 EPHA5 ROBO3 CEACAM7

1.10e-036632352.60.40.10
DomainIg-like_fold

SPEG NEO1 EPHA5 ROBO3 CEACAM7

1.45e-03706235IPR013783
DomainIg_sub

SPEG NEO1 ROBO3 CEACAM7

1.60e-03421234IPR003599
DomainIG

SPEG NEO1 ROBO3 CEACAM7

1.60e-03421234SM00409
DomainIG_LIKE

SPEG NEO1 ROBO3 CEACAM7

2.81e-03491234PS50835
DomainIg_sub2

SPEG NEO1 ROBO3

2.89e-03235233IPR003598
DomainIGc2

SPEG NEO1 ROBO3

2.89e-03235233SM00408
DomainIg-like_dom

SPEG NEO1 ROBO3 CEACAM7

3.06e-03503234IPR007110
DomainTyrKc

TNK1 EPHA5

5.21e-0388232SM00219
DomainTyr_kinase_cat_dom

TNK1 EPHA5

5.21e-0388232IPR020635
DomainPROTEIN_KINASE_TYR

TNK1 EPHA5

6.29e-0397232PS00109
DomainTyr_kinase_AS

TNK1 EPHA5

6.29e-0397232IPR008266
DomainProtein_kinase_ATP_BS

TNK1 SPEG EPHA5

1.09e-02379233IPR017441
DomainPkinase_Tyr

TNK1 EPHA5

1.09e-02129232PF07714
DomainSer-Thr/Tyr_kinase_cat_dom

TNK1 EPHA5

1.24e-02138232IPR001245
DomainAAA+_ATPase

HELZ2 DNAH5

1.34e-02144232IPR003593
DomainAAA

HELZ2 DNAH5

1.34e-02144232SM00382
DomainPROTEIN_KINASE_ATP

TNK1 SPEG EPHA5

1.81e-02459233PS00107
DomainLRR_8

LRRTM1 TPBGL

1.86e-02171232PF13855
DomainLeu-rich_rpt_typical-subtyp

LRRTM1 TPBGL

1.98e-02177232IPR003591
DomainLRR_TYP

LRRTM1 TPBGL

1.98e-02177232SM00369
DomainProt_kinase_dom

TNK1 SPEG EPHA5

2.14e-02489233IPR000719
DomainPROTEIN_KINASE_DOM

TNK1 SPEG EPHA5

2.19e-02493233PS50011
Pubmed

NOVA regulates Dcc alternative splicing during neuronal migration and axon guidance in the spinal cord.

NEO1 EPHA5 ROBO3

1.41e-071623327223328
Pubmed

Neural migration. Structures of netrin-1 bound to two receptors provide insight into its axon guidance mechanism.

NEO1 ROBO3

6.26e-06623224876346
Pubmed

Phenotypic analysis of mice completely lacking netrin 1.

NEO1 ROBO3

4.37e-051523226395479
Pubmed

Fezl regulates the differentiation and axon targeting of layer 5 subcortical projection neurons in cerebral cortex.

NEO1 EPHA5 ROBO3

7.80e-0512623316284245
Pubmed

Zic2-dependent axon midline avoidance controls the formation of major ipsilateral tracts in the CNS.

EPHA5 ROBO3

1.05e-042323224360543
Pubmed

Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion.

SPEG ROBO3 CEACAM7

1.64e-0416223325826454
Pubmed

The transcription factor gene Nfib is essential for both lung maturation and brain development.

NEO1 ROBO3

1.80e-043023215632069
Pubmed

Axon guidance genes control hepatic artery development.

NEO1 CEACAM7

2.60e-043623237497580
Pubmed

ER-export and ARFRP1/AP-1-dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication.

PCDH7 TRPM4 RHBDD3 TMEM87B NEO1

3.39e-0495223538569033
Pubmed

Cytoplasmic Metadherin (MTDH) provides survival advantage under conditions of stress by acting as RNA-binding protein.

DNAH5 PCDH7 NEO1

3.71e-0421423322199357
Pubmed

High-throughput screening of mouse gene knockouts identifies established and novel skeletal phenotypes.

PORCN NEO1

5.86e-045423226273529
GeneFamilyFibronectin type III domain containing

NEO1 EPHA5 ROBO3

1.82e-04160133555
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

SPEG NEO1 ROBO3

1.86e-04161133593
GeneFamilyImmunoglobulin like domain containing

NEO1 ROBO3 CEACAM7

3.17e-04193133594
CoexpressionBENPORATH_PRC2_TARGETS

NDUFA4L2 LRRTM1 GDF7 EPHA5 ROBO3 TMEM59L

1.60e-05650236M8448
CoexpressionGSE20198_UNTREATED_VS_IL12_TREATED_ACT_CD4_TCELL_DN

PORCN TRPM4 NEO1 EPHA5

2.60e-05200234M7361
ToppCellBasal_cells-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

PCDH7 LRRTM1 SPRED3 TMEM59L

1.43e-0616423485487a303194f5244956ec1ca2d1758d38117f41
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-Neuronal-cortical_neurons_1|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

MAL2 NEO1 EPHA5 TMEM59L

3.02e-06198234d81f35c0066558ff96dd06f58fca72cd82e681e8
ToppCellhealthy_donor-Lymphocytic-T_cell-CD4+_T_cell_(ISG_high)|healthy_donor / Disease condition, Lineage, Cell class and subclass

HELZ2 DNAH5 SPEG

4.78e-0513823397f5dc17522462133e582b508ad0ef036e656872
ToppCellChildren_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

NDUFA4L2 PCDH7 SPEG

6.75e-05155233cd7d95cbcad248670e531d80bb83c55e36ebc573
ToppCell343B-Myeloid-Macrophage-SPP1+_Macrophage|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

HELZ2 NDUFA4L2 XKR6

7.01e-051572334183dbed6b31ebe13ef33eb19ba6d0fb4f625953
ToppCell343B-Myeloid-Macrophage-SPP1+_Macrophage|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

HELZ2 NDUFA4L2 XKR6

7.15e-05158233de65af8d3b8514b17978155f31975e2347b75251
ToppCellAdult-Mesenchymal-vascular_smooth_muscle_cell-D175|Adult / Lineage, Cell type, age group and donor

PCDH7 SPEG ROBO3

8.42e-05167233c4e321bb87512ea839f324c92c0f1afea891483f
ToppCelldroplet-Kidney-nan-18m-Epithelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NDUFA4L2 SPEG SPRED3

8.72e-0516923387116c33c5ca8cb1862e103e5607b1df4d264569
ToppCellwk_20-22-Epithelial-PNS-Late_Schwann|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

SPRED3 EPHA5 TMEM59L

9.84e-0517623381924471d8a8c5bd8eedf294c007e25b6cd3e417
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_G2M|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NDUFA4L2 PCDH7 XKR6

1.02e-041782339fc5688cf705a74398d24e10e0aab4758612e72b
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-Tuft-related-BEST4+_epithelial|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MAL2 NEO1 CEACAM7

1.05e-041802337c7c4d64ff99d0710a7d19d8bc29fc9217394db1
ToppCell5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PCDH7 TPBGL TMEM59L

1.05e-04180233f2f6e83127a4a415e65c76a35efa8175fbd5b5d9
ToppCellPericytes-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

NDUFA4L2 PCDH7 SPEG

1.10e-04183233d04deef7cd4e1738227a6593b84874ce0168c773
ToppCell21-Trachea-Epithelial-Goblet-like_secretory|Trachea / Age, Tissue, Lineage and Cell class

NDUFA4L2 MAL2 TRPM4

1.16e-04186233f8cddad28896f0edf10a8645fa49a011b22b120d
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DNAH5 MAL2 XKR6

1.16e-041862332ea5ff14861e5f91d0e6a5767c403a24045d715c
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

MAL2 SPRED3 EPHA5

1.20e-04188233b73e8a40393c3f656e2fcfe395a761b1f985c254
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MAL2 PCDH7 EPHA5

1.21e-04189233bfc76a72b600d641c8fe58346e5d8986c34f3981
ToppCellHealthy_Control-Epithelial-Epithelial|Healthy_Control / Condition, Lineage, Cell class and cell subclass

DNAH5 MAL2 PCDH7

1.25e-0419123315b9386b26caaa7d15f704c4a18881e1ce918a21
ToppCellHealthy_Control-Epithelial|Healthy_Control / Condition, Lineage, Cell class and cell subclass

DNAH5 MAL2 PCDH7

1.25e-04191233fdcdadbfc9ccae175abe4de8c7428ac4f6a67fde
ToppCellHealthy_Control-Epithelial-Epithelial-|Healthy_Control / Condition, Lineage, Cell class and cell subclass

DNAH5 MAL2 PCDH7

1.25e-0419123328caedb2e448e0c7f494100d714fa7cdcf150691
ToppCell390C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

NDUFA4L2 PCDH7 TMEM59L

1.27e-04192233c6795ceba90f1a5d441dff92a737b9c7d28b06b0
ToppCelldroplet-Lung-18m-Mesenchymal-myofibroblast|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NDUFA4L2 PCDH7 SPEG

1.27e-041922332cc712186e37fb21a964c032765c36a8b4a852cf
ToppCellP28-Mesenchymal-myocytic_cell-vascular_associated_smooth_muscle_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

NDUFA4L2 PCDH7 SPEG

1.27e-0419223387c7780cf72f4c204f2a5f6655309d47a23c08ae
ToppCellP15-Mesenchymal-myocytic_cell-vascular_associated_smooth_muscle_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

NDUFA4L2 PCDH7 SPEG

1.27e-04192233a476895b7b252c388d6346eacbc72f0115b1443e
ToppCell390C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

NDUFA4L2 PCDH7 TMEM59L

1.27e-041922335d24bb6c6c17a6b803b241d065b31896a7d86c37
ToppCellPCW_10-12-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

DNAH5 MAL2 TMEM59L

1.29e-04193233b25cdca3a1e381784ae48ca73c51cbb6ac62b811
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NDUFA4L2 PCDH7 SPEG

1.29e-04193233469a7f1c2ff7137cc5a064464456911f67f92e70
ToppCellP28-Mesenchymal-myocytic_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

NDUFA4L2 PCDH7 SPEG

1.31e-0419423383e45441c74b7f50b6725876b583229280179dc2
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NDUFA4L2 PCDH7 SPEG

1.33e-04195233c51b1bee79e77aa2ac444a4883ef533c0095eaad
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NDUFA4L2 PCDH7 SPEG

1.33e-0419523343d372373367b71243c6ea958aedccde4478618f
ToppCell11.5-Distal-Epithelial-Secretory_progenitor|Distal / Age, Tissue, Lineage and Cell class

DNAH5 MAL2 TMEM59L

1.35e-041962332648d64b0e7b59ae78182d55f32699ceea37ff8d
ToppCell343B-Fibroblasts-Fibroblast-K_(Pericytes)|343B / Donor, Lineage, Cell class and subclass (all cells)

NDUFA4L2 PCDH7 SPEG

1.37e-0419723378d45d11820ec379942c4c3defd619d5f8cc8e1f
ToppCellParenchymal-NucSeq-Stromal-Myofibroblastic-Muscle_perivascular_immune_recruiting|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SPEG SPRED3 GDF7

1.37e-041972333332b9b5bf78f0203ebbd94257a36e9054d896c3
ToppCell343B-Fibroblasts-Fibroblast-K_(Pericytes)-|343B / Donor, Lineage, Cell class and subclass (all cells)

NDUFA4L2 PCDH7 SPEG

1.37e-0419723331bc9fd679d78550541d4158568e8dd09ff29e8e
ToppCellBronchial-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_pulmonary|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

NDUFA4L2 SPEG GDF7

1.39e-04198233705118a5db366b43ffd3389c60e4cb392ad3f2e6
ToppCellFetal_29-31_weeks-Epithelial-club_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DNAH5 MAL2 GDF7

1.39e-041982336ba5e5970109a04ed968bac7ff099ae250c579dc
ToppCellFetal_29-31_weeks-Epithelial-club_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DNAH5 MAL2 GDF7

1.39e-041982335fc25b008a4d8d6bec83923a16f64dd9e1ff1f2d
ToppCellBAL-Mild-Epithelial-Epithelial|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DNAH5 MAL2 PCDH7

1.41e-041992331ee4010d8557564e25e8ee00b914c2dfd9037838
ToppCellBAL-Mild-Epithelial-Epithelial|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

DNAH5 MAL2 PCDH7

1.41e-041992331df69c0cb5f759f6a2152521842506a75bb95cae
ToppCellMild-Epithelial|Mild / Condition, Lineage, Cell class and cell subclass

DNAH5 MAL2 PCDH7

1.41e-04199233ec5fff80e2a8a94fbaf1fdcc6d45c8d7c6252e18
ToppCellBAL-Mild-Epithelial|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DNAH5 MAL2 PCDH7

1.41e-0419923374087b4b5e567310fc4ac58fb267ff651a180680
ToppCellMild-Epithelial-Epithelial-|Mild / Condition, Lineage, Cell class and cell subclass

DNAH5 MAL2 PCDH7

1.41e-0419923381115bbd2c10bfdd38376d2075f03a59c31870d2
ToppCellMild_COVID-19-Epithelial|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）

DNAH5 MAL2 PCDH7

1.41e-0419923372689bda7476930887ae007682fcab27f956f050
ToppCellBAL-Mild-Epithelial|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

DNAH5 MAL2 PCDH7

1.41e-0419923300b5ce099c50a5e1786ce2b3a06ee0931a8205a4
ToppCellMild-Epithelial-Epithelial|Mild / Condition, Lineage, Cell class and cell subclass

DNAH5 MAL2 PCDH7

1.41e-0419923391308b255783ad4029e5575028c18d7550832c51
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia/MHC|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NDUFA4L2 MCFD2 TMEM59L

1.44e-04200233ac5843142e0f8a5bcd2c3a784ea13b2f955a32fd
ToppCell11.5-Airway|11.5 / Age, Tissue, Lineage and Cell class

NDUFA4L2 MAL2 TMEM59L

1.44e-042002339e3a8978b76ee9ba1ccc220f128dad081eceba1a
ToppCell343B-Fibroblasts-Fibroblast-K_(Pericytes)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

NDUFA4L2 PCDH7 SPEG

1.44e-04200233b50de1f8c8f598e281951e4587f2d96c11aac836
ToppCell343B-Fibroblasts-Fibroblast-K_(Pericytes)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

NDUFA4L2 PCDH7 SPEG

1.44e-042002334fb6fd703aca9a992924245105ad99163146a415
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Bcl6-Excitatory_Neuron.Slc17a7.Bcl6-Tshz2-Syt2_(Layer_5a,_Entorhinal_cortex,_Tshz1+)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

TNK1 GDF7

3.14e-0451232adc73d6909d75ad432aef884dae540b7e48cecd6
ToppCellThalamus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a7-Tac2-Excitatory_Neuron.Slc17a7.Tac2.Chat_(Habenular_cholinergic_cells)|Thalamus / BrainAtlas - Mouse McCarroll V32

TPBGL ROBO3

8.10e-048223251dd9ab3ddb26d3d3395d0c1a156a12a86caf89b
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NDUFA4L2 TPBGL

1.02e-039223284ac97a16920b912a67ea80e71146eddf9dfa92f
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Metaplastic_Carcinoma-4|TCGA-Breast / Sample_Type by Project: Shred V9

LRRTM1 GDF7

1.22e-031012321291191e8de321ecb5f5b4ef3f836328429aeee5
ToppCellEntopeduncular-Macroglia-POLYDENDROCYTE-P3-Tnr|Entopeduncular / BrainAtlas - Mouse McCarroll V32

TNK1 DNAH5

1.42e-03109232e3696d84da1dcd15f15d0434ea9d1955f2af22d6
ToppCellEntopeduncular-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendendrocytes_NG2_cells_(Tnr-Cspg5)-|Entopeduncular / BrainAtlas - Mouse McCarroll V32

TNK1 DNAH5

1.42e-031092326678036ff66c825a18d2506e33be421c27cf82e1
ToppCellEntopeduncular-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendendrocytes_NG2_cells_(Tnr-Cspg5)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

TNK1 DNAH5

1.42e-0310923287f647cfebbb7de725e434cc27058e1c6accbb90
ToppCellEntopeduncular-Macroglia-POLYDENDROCYTE-P3|Entopeduncular / BrainAtlas - Mouse McCarroll V32

TNK1 DNAH5

1.42e-03109232c9d1e69f9841135f4d114563a293a69a8ba5f965
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_ALM_Npw|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

XKR6 ROBO3

1.53e-03113232165de4316059222f33d1e51aeff4554037c0b937
ToppCellBronchial-10x5prime-Stromal-Schwann-Schwann_nonmyelinating|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SPRED3 ROBO3

1.61e-03116232b0a3c109c5f20ab699e53bf8ab3903d102f5f315
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Neuronal-Intermediate|GW19 / Sample Type, Dataset, Time_group, and Cell type.

DNAH5 XKR6

1.72e-03120232eb5b88c47dd4a6f9b55ace24f19d4e81d4ed31e1
ToppCellSmart-seq2-bone_marrow_(Smart-seq2)-lymphocytic-B_lymphocytic-plasmablast|bone_marrow_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MAL2 CEACAM7

1.95e-031282323c810fc4934dee4de2b8b64a2e152547b08c6f8d
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_104|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NDUFA4L2 ROBO3

1.98e-03129232e7a15f98c3e6e4ee317e21958be3e413e3acd101
ToppCellLPS-antiTNF-Epithelial_alveolar-Mes-like|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RXFP4 EPHA5

2.14e-0313423264979e1a056b7406e1be39c5ebe2f8d731ac3c17
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage_4|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

HELZ2 TPBGL

2.14e-031342329e12aac8f42790c2f104dfd61c87aa99fc7925f1
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Mucinous_Rectal_Adenocarcinoma-10|TCGA-Colorectal / Sample_Type by Project: Shred V9

TPBGL SPRED3

2.20e-03136232feb957df4bff3266cb9a7382b16fc927ae03b9b4
ToppCellLPS_only-Epithelial_alveolar-AT_1-AT1_Progenitor|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH5 MAL2

2.27e-03138232615822e542f12aa83df1561e262b8d72bdefc60e
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling-Cycling_Connecting_Tubule_Cell_low-phase|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PORCN SPRED3

2.27e-03138232cd2f4682fcfd0275ce0640150bbb18da839e5c0a
ToppCellPBMC-Mild-Lymphocyte-B-B_cell-B_memory-B_activate-7|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

XKR6 GDF7

2.30e-03139232693ca81f5831b63fe6148ac755631e09f67d0ebf
ToppCellE16.5-samps-Mesenchymal-Myofibroblast-Smooth_Muscle-like_MyoFibroblast|E16.5-samps / Age Group, Lineage, Cell class and subclass

PCDH7 SPRED3

2.33e-031402325623a0a68403fc00166b7d13d13e184a718d9bdd
ToppCell368C-Myeloid-Macrophage-SPP1+_Macrophage_4|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

NDUFA4L2 TPBGL

2.40e-031422325ef69032ed7dc5f2244b84e8c6662290bf59a34b
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L2/3_IT-L2/3_IT_ALM_Macc1_Lrg1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

XKR6 ROBO3

2.40e-03142232d08e1880425d285c4433014fe0242ac7ff7734af
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MAL2 PCDH7

2.40e-031422326469cf82552b39f63e20b841c9eed50de6f58d54
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

MAL2 ROBO3

2.43e-031432325fb5a4ea93e5cce55d427e3b4a50a979504fad3c
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NDUFA4L2 TMEM59L

2.46e-03144232121853910eeea1ea0642b3cc99f9200015480368
ToppCellEntopeduncular-Macroglia-POLYDENDROCYTE|Entopeduncular / BrainAtlas - Mouse McCarroll V32

TNK1 DNAH5

2.53e-03146232a317f14a1aab11ffcce65baeb1c475c04324315f
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar-Macro_c4-DNAJB1|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

MAL2 SPEG

2.60e-03148232e73860f6b8021482f82b83ccd2b7e1dfd7d9e80b
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DNAH5 MAL2

2.60e-031482329fe3c0a5904b8e9a0f28130f8d84d4f2a819b06c
ToppCell3'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PCDH7 EPHA5

2.67e-03150232aa11579a57d671a55e64183d35c1340fda6dec14
ToppCellPericytes-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

NDUFA4L2 SPEG

2.67e-03150232dbc202bd6db4fb5c8b2abd1200e074a2a9e63a59
ToppCellE16.5-samps-Myeloid-Fetal_macrophage-macrophage_-_intermediate_-_unactivated|E16.5-samps / Age Group, Lineage, Cell class and subclass

TPBGL GDF7

2.67e-0315023260fdd266aaca1b589b9a77465a4a7fad4921339a
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-lymphoid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCDH7 SPEG

2.74e-03152232acfafdb64bd5b0eb7371b04cfef51ed2798e9b30
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NDUFA4L2 SPEG

2.74e-031522320cb5f4dfae04e3f4eba502bbf229007d5fa3884d
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-common_lymphoid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCDH7 SPEG

2.74e-031522329d6c88ceca0569dbeb12e488acec7fcb7f972f03
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NDUFA4L2 SPEG

2.74e-03152232ba89ffb5a8bb33c188f854f54b39123b6d73496a
ToppCell3'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PCDH7 EPHA5

2.77e-0315323282b77c8bae49dd63b8f10eb67df66ca71d0bb315
ToppCellmetastatic_Brain-Fibroblasts-Smooth_muscle_cells|Fibroblasts / Location, Cell class and cell subclass

SPEG XKR6

2.81e-03154232423f58fc7dcef068458cbf7b4ee989e37227041e
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_VISp_Col27a1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

XKR6 ROBO3

2.81e-03154232d22902d2922784583f7016453768ed05b14b965e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal--glomerular_mesenchymal_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NDUFA4L2 SPEG

2.81e-031542323211f003f4d1735c7cab9b6cc68af3e0bbfba35e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NDUFA4L2 SPEG

2.81e-03154232c0fe767fc9ab45b2dfa71171f2a673a4a8decbaf
ToppCell10x5'-blood-Lymphocytic_T_CD8-Trm_gut_CD8|blood / Manually curated celltypes from each tissue

XKR6 ROBO3

2.81e-03154232c77a02df403358361aca86c679d5c43a64ff2f7f
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NDUFA4L2 SPEG

2.81e-031542324c2a7590791c2255b15dab82c3622f71f9ffd949
ToppCellPND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HELZ2 PORCN

2.88e-03156232895927228c93cd090303984c5be6ebfb59ed6f3a
ToppCellCOVID-19-lung-Mesothelial|lung / Disease (COVID-19 only), tissue and cell type

SPEG EPHA5

2.88e-03156232e1f563869b3bf997eaa2e756e31b53db1a478903
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MAL2 PCDH7

2.92e-0315723210989c7046fc859f137c7cef3296508d4476f11f
ToppCell10x5'-blood-Lymphocytic_T_CD4-Trm_Th1/Th17|blood / Manually curated celltypes from each tissue

RHBDD3 NEO1

2.92e-03157232c99cb26d831c25038f2aa1b1c0f7ba52facb2e7a
ToppCellHealthy/Control-CD8+_T_naive|World / Disease group and Cell class

TNK1 ROBO3

2.95e-0315823270680b29428b6bf882b1fae36f924b775961176b
ToppCellChildren_(3_yrs)-Epithelial-basal_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

DNAH5 CEACAM7

2.95e-03158232d78e7e52657dc094430291fec07e9c298be9e584
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

DNAH5 GDF7

2.99e-031592328680b054622f573a82b1625fb93c2d5db81d1034
ToppCellHealthy/Control-CD8+_T_naive|Healthy/Control / Disease group and Cell class

TNK1 ROBO3

3.03e-03160232e1386c21fcbbf57fa32d8bdfba3cb1887477ff73
ToppCellAdult-Mesenchymal-airway_smooth_muscle_cell-D231|Adult / Lineage, Cell type, age group and donor

PCDH7 SPEG

3.03e-03160232d783d29150033e9181c0e30870070268fed3fd85
Diseasediastolic blood pressure, systolic blood pressure

MAL2 RHBDD3 SPEG GDF7

9.55e-04670204EFO_0006335, EFO_0006336
Diseaseaggressive behaviour measurement, ADHD symptom measurement

PCDH7 XKR6

9.68e-0468202EFO_0007826, EFO_0007860
Diseasedentures

NEO1 TMEM59L

1.03e-0370202EFO_0010078
Diseasedental caries, dentures

NEO1 TMEM59L

1.03e-0370202EFO_0003819, EFO_0010078
Diseaserisk-taking behaviour

PCDH7 NEO1 XKR6 EPHA5

1.55e-03764204EFO_0008579
Diseasedescending aortic diameter

MAL2 GDF7

1.61e-0388202EFO_0021788
DiseaseStuttering

TMEM87B LRRTM1

4.18e-03143202HP_0025268
DiseaseAdenocarcinoma of lung (disorder)

TNK1 EPHA5

8.48e-03206202C0152013

Protein segments in the cluster

PeptideGeneStartEntry
RRSGLPRWILACCLF

TMEM59L

261

Q9UK28
CYSAPRRAPLWTCLL

EPHA5

31

P54756
RRAPLWTCLLLCAAL

EPHA5

36

P54756
ACPYRVCIPWQGLLL

CEACAM7

6

Q14002
LLRTPFLCGLLWAFC

MCFD2

6

Q8NI22
LGLCLYWLLRRPSGV

LRRTM1

6

Q86UE6
YWLLRRPSGVVLCLL

LRRTM1

11

Q86UE6
RGWCLGCCLLLPLSL

PCDH7

11

O60245
LYLLRLALRSPDVCW

NDUFA4L2

36

Q9NRX3
CLACRLLWRLGLPSY

PORCN

36

Q9H237
ACYGCSLGLALRRWR

MAL2

161

Q969L2
WLLLPARCCLALGLQ

HELZ2

446

Q9BYK8
LDCFRRLLLIRSWCP

DNAH5

3991

Q8TE73
CGVRLCLLRFPSRYW

RXFP4

186

Q8TDU9
AAALCLWLLSACRPR

GDF7

6

Q7Z4P5
FWLYCLLLLGRRAPG

NEO1

16

Q92859
LCRTLAGCWPLRLLA

RHBDD3

201

Q9Y3P4
YWGCRSACLRSLLGR

XKR6

66

Q5GH73
WLCRGRLLQPALLKC

SPEG

1001

Q15772
PGRLLVRRLSCLWCA

SPRED3

321

Q2MJR0
CGALLLGLCAALYWR

ROBO3

901

Q96MS0
ARAPLLRVALCLLCW

TMEM87B

21

Q96K49
PLCSRALYSLALRCW

TNK1

346

Q13470
LRCGCAARPLLAWLR

TPBGL

236

P0DKB5
LLLRRCPLWGDATCL

TRPM4

641

Q8TD43