Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionaspartic-type endopeptidase activity

ERVK-6 ERVK-7 ERVK-21 ERVK-9 ERVK-10 ERVK-8 ERVK-18 ERVK-19 ERVK-25 ERVK-24

1.76e-15379910GO:0004190
GeneOntologyMolecularFunctionaspartic-type peptidase activity

ERVK-6 ERVK-7 ERVK-21 ERVK-9 ERVK-10 ERVK-8 ERVK-18 ERVK-19 ERVK-25 ERVK-24

2.37e-15389910GO:0070001
GeneOntologyMolecularFunctionendopeptidase activity

ERVK-6 TPSAB1 PAMR1 CAPN3 ERVK-7 ERVK-21 ERVK-9 ERVK-10 TPSD1 ERVK-8 ERVK-18 ERVK-19 ERVK-25 ERVK-24 MMP17 TPSB2 TMPRSS11A

3.68e-114309917GO:0004175
GeneOntologyMolecularFunctionpeptidase activity

ERVK-6 TPSAB1 PAMR1 CAPN3 ERVK-7 ERVK-21 ERVK-9 ERVK-10 TPSD1 ERVK-8 ERVK-18 ERVK-19 ERVK-25 ERVK-24 MMP17 TPSB2 USP47 TMPRSS11A

3.15e-096549918GO:0008233
GeneOntologyMolecularFunctionRNA-directed DNA polymerase activity

ERVK-6 SGIP1 ERVK-7 ERVK-10 ERVK-8

5.23e-0914995GO:0003964
GeneOntologyMolecularFunctionRNA-DNA hybrid ribonuclease activity

ERVK-6 ERVK-7 ERVK-10 ERVK-8

1.83e-0711994GO:0004523
GeneOntologyMolecularFunctionDNA polymerase activity

ERVK-6 SGIP1 ERVK-7 ERVK-10 ERVK-8

1.19e-0638995GO:0034061
GeneOntologyMolecularFunctionRNA stem-loop binding

ERVK-6 ERVK-7 ERVK-10 ERVK-8

3.19e-0621994GO:0035613
GeneOntologyMolecularFunctioncatalytic activity, acting on DNA

ERVK-6 SGIP1 NTHL1 CHD1 ERVK-7 ERVK-10 CRY2 RECQL4 ERVK-8

6.22e-06262999GO:0140097
GeneOntologyMolecularFunctionstructural molecule activity

ERVK-6 CAPN3 ERVK-7 ERVK-21 ERVK-9 ERVK-10 SPON1 ASPH ERVK-8 ERVK-18 ERVK-19 ERVK-25 ERVK-24 MUC4 MYBPC3

3.19e-058919915GO:0005198
GeneOntologyMolecularFunctionRNA endonuclease activity, producing 5'-phosphomonoesters

ERVK-6 ERVK-7 ERVK-10 ERVK-8

3.31e-0537994GO:0016891
GeneOntologyMolecularFunctionfolic acid receptor activity

FOLR1 FOLR3

7.28e-053992GO:0061714
GeneOntologyMolecularFunctionendonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters

ERVK-6 ERVK-7 ERVK-10 ERVK-8

7.91e-0546994GO:0016893
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH3 DNAH10 DNAH11

9.14e-0518993GO:0008569
GeneOntologyMolecularFunctiontransition metal ion binding

ERVK-6 CYP1B1 NAPEPLD ERVK-7 ERVK-21 ERVK-9 ERVK-10 F8 LOX SUMF1 RECQL4 ERVK-8 ERVK-19 KDM4A ERVK-24 MMP17

2.37e-0411899916GO:0046914
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DNAH3 DNAH10 DNAH11

3.54e-0428993GO:0051959
GeneOntologyMolecularFunctionendonuclease activity

ERVK-6 NTHL1 ERVK-7 ERVK-10 ERVK-8

5.83e-04136995GO:0004519
GeneOntologyMolecularFunctionRNA endonuclease activity

ERVK-6 ERVK-7 ERVK-10 ERVK-8

6.42e-0479994GO:0004521
GeneOntologyMolecularFunctiontransferase activity, transferring phosphorus-containing groups

ERVK-6 SGIP1 PI4K2A ERVK-7 ERVK-10 STK32C ACVR1B LCK MST1R FAM20B ERVK-8 IKBKB WNK2

7.31e-049389913GO:0016772
GeneOntologyMolecularFunctiondynein intermediate chain binding

DNAH3 DNAH10 DNAH11

8.13e-0437993GO:0045505
GeneOntologyMolecularFunctionvolume-sensitive anion channel activity

LRRC8C LRRC8D

8.56e-049992GO:0005225
GeneOntologyMolecularFunctionnucleotidyltransferase activity

ERVK-6 SGIP1 ERVK-7 ERVK-10 ERVK-8

9.63e-04152995GO:0016779
GeneOntologyMolecularFunctionstructural constituent of muscle

CAPN3 ASPH MYBPC3

1.26e-0343993GO:0008307
GeneOntologyMolecularFunctioncatalytic activity, acting on a nucleic acid

ERVK-6 SGIP1 NTHL1 CHD1 ERVK-7 ERVK-10 CRY2 RECQL4 ERVK-8 HELZ

1.36e-036459910GO:0140640
GeneOntologyMolecularFunctionzinc ion binding

ERVK-6 NAPEPLD ERVK-7 ERVK-21 ERVK-9 ERVK-10 RECQL4 ERVK-8 ERVK-19 KDM4A ERVK-24 MMP17

1.51e-038919912GO:0008270
GeneOntologyMolecularFunctiontitin binding

CAPN3 MYBPC3

2.13e-0314992GO:0031432
GeneOntologyMolecularFunctionserine-type endopeptidase activity

TPSAB1 PAMR1 TPSD1 TPSB2 TMPRSS11A

2.57e-03190995GO:0004252
GeneOntologyBiologicalProcessDNA integration

ERVK-6 ERVK-7 ERVK-10 ERVK-8

3.45e-0713994GO:0015074
GeneOntologyBiologicalProcesscell-cell fusion

ERVK-6 ERVK-21 ERVK-9 ERVK-8 ERVK-19

5.57e-0585995GO:0140253
GeneOntologyBiologicalProcesssyncytium formation by plasma membrane fusion

ERVK-6 ERVK-21 ERVK-9 ERVK-8 ERVK-19

5.57e-0585995GO:0000768
GeneOntologyBiologicalProcesssyncytium formation

ERVK-6 ERVK-21 ERVK-9 ERVK-8 ERVK-19

6.94e-0589995GO:0006949
GeneOntologyBiologicalProcessviral process

ERVK-6 CHD1 ERVK-7 ERVK-21 ERVK-9 ERVK-10 ERVK-8 ERVK-19 ERVK-24 TMPRSS11A

7.86e-054649910GO:0016032
GeneOntologyBiologicalProcessDNA synthesis involved in DNA repair

ERVK-6 ERVK-7 ERVK-10 ERVK-8

8.26e-0548994GO:0000731
GeneOntologyBiologicalProcessdrinking behavior

TACR1 EN1 MMP17

8.31e-0518993GO:0042756
GeneOntologyBiologicalProcessfeeding behavior

CEACAM5 SGIP1 NAPEPLD TACR1 EN1 MMP17

1.31e-04162996GO:0007631
GeneOntologyCellularComponentdynein complex

DNAH3 DNAH10 DNAI4 DNAH11

1.35e-04541014GO:0030286
GeneOntologyCellularComponentaxonemal dynein complex

DNAH3 DNAH10 DNAI4

2.33e-04251013GO:0005858
Domain-

DMXL2 LRWD1 DCAF8L2 EDC4 MST1R WDR97 WRAP73 DNAI4 ELP2

3.55e-053339192.130.10.10
DomainWD40/YVTN_repeat-like_dom

DMXL2 LRWD1 DCAF8L2 EDC4 MST1R WDR97 WRAP73 DNAI4 ELP2

3.72e-05335919IPR015943
DomainDynein_heavy_chain_D4_dom

DNAH3 DNAH10 DNAH11

3.92e-0514913IPR024317
DomainDynein_HC_stalk

DNAH3 DNAH10 DNAH11

3.92e-0514913IPR024743
DomainDynein_heavy_dom-2

DNAH3 DNAH10 DNAH11

3.92e-0514913IPR013602
DomainDHC_N2

DNAH3 DNAH10 DNAH11

3.92e-0514913PF08393
DomainMT

DNAH3 DNAH10 DNAH11

3.92e-0514913PF12777
DomainAAA_8

DNAH3 DNAH10 DNAH11

3.92e-0514913PF12780
DomainATPase_dyneun-rel_AAA

DNAH3 DNAH10 DNAH11

3.92e-0514913IPR011704
DomainAAA_5

DNAH3 DNAH10 DNAH11

3.92e-0514913PF07728
DomainDHC_fam

DNAH3 DNAH10 DNAH11

4.88e-0515913IPR026983
DomainDynein_heavy_dom

DNAH3 DNAH10 DNAH11

4.88e-0515913IPR004273
DomainDynein_heavy

DNAH3 DNAH10 DNAH11

4.88e-0515913PF03028
DomainWD40

DMXL2 LRWD1 DCAF8L2 EDC4 WDR97 WRAP73 DNAI4 ELP2

4.92e-05268918SM00320
DomainWD40_repeat

DMXL2 LRWD1 DCAF8L2 EDC4 WDR97 WRAP73 DNAI4 ELP2

5.46e-05272918IPR001680
DomainWD_REPEATS_2

DMXL2 LRWD1 DCAF8L2 EDC4 WDR97 WRAP73 DNAI4 ELP2

6.53e-05279918PS50082
DomainWD_REPEATS_REGION

DMXL2 LRWD1 DCAF8L2 EDC4 WDR97 WRAP73 DNAI4 ELP2

6.53e-05279918PS50294
DomainTRYPSIN_SER

TPSAB1 PAMR1 TPSD1 TPSB2 TMPRSS11A

1.69e-04106915PS00135
DomainTRYPSIN_HIS

TPSAB1 PAMR1 TPSD1 TPSB2 TMPRSS11A

1.77e-04107915PS00134
DomainPeptidase_S1A

TPSAB1 PAMR1 TPSD1 TPSB2 TMPRSS11A

2.28e-04113915IPR001314
DomainLRRC8_Pannexin-like

LRRC8C LRRC8D

2.33e-045912IPR021040
DomainPannexin_like

LRRC8C LRRC8D

2.33e-045912PF12534
DomainFolate_rcpt

FOLR1 FOLR3

2.33e-045912IPR004269
DomainTRYPSIN_DOM

TPSAB1 PAMR1 TPSD1 TPSB2 TMPRSS11A

2.47e-04115915PS50240
DomainTryp_SPc

TPSAB1 PAMR1 TPSD1 TPSB2 TMPRSS11A

2.68e-04117915SM00020
DomainWD40

DMXL2 LRWD1 DCAF8L2 WDR97 WRAP73 DNAI4 ELP2

2.73e-04259917PF00400
DomainTrypsin

TPSAB1 PAMR1 TPSD1 TPSB2 TMPRSS11A

3.13e-04121915PF00089
DomainTrypsin_dom

TPSAB1 PAMR1 TPSD1 TPSB2 TMPRSS11A

3.13e-04121915IPR001254
DomainPeptidase_S1_PA

TPSAB1 PAMR1 TPSD1 TPSB2 TMPRSS11A

3.38e-04123915IPR009003
DomainWD_REPEATS_1

DMXL2 LRWD1 EDC4 WDR97 WRAP73 DNAI4 ELP2

4.19e-04278917PS00678
DomainWD40_repeat_dom

DMXL2 LRWD1 DCAF8L2 EDC4 WDR97 DNAI4 ELP2

6.20e-04297917IPR017986
DomainFolate_rcpt-like

FOLR1 FOLR3

6.45e-048912IPR018143
DomainDHC_N1

DNAH10 DNAH11

6.45e-048912PF08385
DomainDynein_heavy_dom-1

DNAH10 DNAH11

6.45e-048912IPR013594
DomainFolate_rec

FOLR1 FOLR3

6.45e-048912PF03024
DomainTRYPSIN_SER

TPSAB1 TPSD1 TPSB2 TMPRSS11A

9.79e-0490914IPR033116
DomainTRYPSIN_HIS

TPSAB1 TPSD1 TPSB2 TMPRSS11A

1.61e-03103914IPR018114
DomainHSP70_2

HSPA12B HSPA12A

3.04e-0317912PS00329
DomainHSP70_3

HSPA12B HSPA12A

3.04e-0317912PS01036
DomainHSP70_1

HSPA12B HSPA12A

3.04e-0317912PS00297
DomainHsp_70_fam

HSPA12B HSPA12A

3.41e-0318912IPR013126
DomainAAA+_ATPase

DNAH3 DNAH10 ABCA13 DNAH11

5.39e-03144914IPR003593
DomainAAA

DNAH3 DNAH10 ABCA13 DNAH11

5.39e-03144914SM00382
DomainIPT

MST1R PKHD1

7.61e-0327912SM00429
Pubmed

Quantitation of HERV-K env gene expression and splicing in human breast cancer.

ERVK-6 ERVK-7 ERVK-21 ERVK-18 ERVK-19

2.17e-135104512629516
Pubmed

A revised nomenclature for transcribed human endogenous retroviral loci.

ERVK-6 ERVK-7 ERVK-21 ERVK-9 ERVK-10 ERVK-8 ERVK-18 ERVK-19 ERVK-25 ERVK-24

2.69e-13941041021542922
Pubmed

Expression patterns of transcribed human endogenous retrovirus HERV-K(HML-2) loci in human tissues and the need for a HERV Transcriptome Project.

ERVK-21 ERVK-9 ERVK-10 ERVK-18 ERVK-25 ERVK-24

1.11e-1118104618664271
Pubmed

Many human endogenous retrovirus K (HERV-K) proviruses are unique to humans.

ERVK-6 ERVK-7 ERVK-10 ERVK-24

7.54e-114104410469592
Pubmed

Genomewide screening for fusogenic human endogenous retrovirus envelopes identifies syncytin 2, a gene conserved on primate evolution.

ERVK-6 ERVK-21 ERVK-9 ERVK-8 ERVK-19

1.69e-1012104514557543
Pubmed

Genome-wide screening, cloning, chromosomal assignment, and expression of full-length human endogenous retrovirus type K.

ERVK-6 ERVK-18 ERVK-19

2.60e-083104310516026
Pubmed

Characterization of genes encoding known and novel human mast cell tryptases on chromosome 16p13.3.

TPSAB1 TPSD1 TPSB2

2.60e-08310439920877
Pubmed

Human subjects are protected from mast cell tryptase deficiency despite frequent inheritance of loss-of-function mutations.

TPSAB1 TPSD1 TPSB2

2.60e-083104319748655
Pubmed

Human endogenous retrovirus K10: expression of Gag protein and detection of antibodies in patients with seminomas.

ERVK-6 ERVK-10 ERVK-19

1.04e-07410437983737
Pubmed

Human endogenous retrovirus HERV-K(HML-2) proviruses with Rec protein coding capacity and transcriptional activity.

ERVK-6 ERVK-9 ERVK-19

5.16e-076104315063128
Pubmed

New developments in the genetics and activation of mast cell proteases.

TPSAB1 TPSD1 TPSB2

5.16e-076104312217407
Pubmed

Survey of human genes of retroviral origin: identification and transcriptome of the genes with coding capacity for complete envelope proteins.

ERVK-6 ERVK-21 ERVK-19

3.07e-0610104312970426
Pubmed

The structure of the human betaII-tryptase tetramer: fo(u)r better or worse.

TPSAB1 TPSB2

8.86e-062104210500112
Pubmed

The mouse mast cell-restricted tetramer-forming tryptases mouse mast cell protease 6 and mouse mast cell protease 7 are critical mediators in inflammatory arthritis.

TPSAB1 TPSD1

8.86e-062104218668540
Pubmed

Characterization of a tryptase mRNA expressed in the human basophil cell line KU812.

TPSAB1 TPSB2

8.86e-06210428434231
Pubmed

Increase in TPSB2 and TPSD1 Expression in Synovium of Hip Osteoarthritis Patients Who Are Overweight.

TPSD1 TPSB2

8.86e-062104237511292
Pubmed

Alternate mRNA splicing in multiple human tryptase genes is predicted to regulate tetramer formation.

TPSAB1 TPSD1

8.86e-062104218854315
Pubmed

Cloning and characterization of a second complementary DNA for human tryptase.

TPSAB1 TPSB2

8.86e-06210422203827
Pubmed

Expression of human endogenous retrovirus type K envelope glycoprotein in insect and mammalian cells.

ERVK-6 ERVK-19

8.86e-06210429060628
Pubmed

Combined use of lysyl oxidase, carcino-embryonic antigen, and carbohydrate antigens improves the sensitivity of biomarkers in predicting lymph node metastasis and peritoneal metastasis in gastric cancer.

CEACAM5 LOX

8.86e-062104225060181
Pubmed

Evolutionary relationships within a subgroup of HERV-K-related human endogenous retroviruses.

ERVK-6 ERVK-19

8.86e-06210429460924
Pubmed

Characterization of two highly polymorphic human tryptase loci and comparison with a newly discovered monkey tryptase ortholog.

TPSAB1 TPSB2

8.86e-062104210898108
Pubmed

Fate of two mast cell tryptases in V3 mastocytosis and normal BALB/c mice undergoing passive systemic anaphylaxis: prolonged retention of exocytosed mMCP-6 in connective tissues, and rapid accumulation of enzymatically active mMCP-7 in the blood.

TPSAB1 TPSD1

8.86e-06210429064323
Pubmed

Essential role for mast cell tryptase in acute experimental colitis.

TPSAB1 TPSD1

8.86e-062104221173247
Pubmed

Mast Cell Protease 7 Promotes Angiogenesis by Degradation of Integrin Subunits.

TPSAB1 TPSD1

8.86e-062104231013764
Pubmed

Human beta-tryptase is a ring-like tetramer with active sites facing a central pore.

TPSAB1 TPSB2

8.86e-06210429521329
Pubmed

Human mast cell tryptase: multiple cDNAs and genes reveal a multigene serine protease family.

TPSAB1 TPSB2

8.86e-06210422187193
Pubmed

Delta tryptase is expressed in multiple human tissues, and a recombinant form has proteolytic activity.

TPSAB1 TPSD1

8.86e-062104212391231
Pubmed

Natural disruption of the mouse mast cell protease 7 gene in the C57BL/6 mouse.

TPSAB1 TPSD1

8.86e-06210428576265
Pubmed

Structural requirements and mechanism for heparin-dependent activation and tetramerization of human betaI- and betaII-tryptase.

TPSAB1 TPSB2

8.86e-062104215567416
Pubmed

Two Hsp70 family members expressed in atherosclerotic lesions.

HSPA12B HSPA12A

8.86e-062104212552099
Pubmed

Human tryptases alpha and beta/II are functionally distinct due, in part, to a single amino acid difference in one of the surface loops that forms the substrate-binding cleft.

TPSAB1 TPSB2

8.86e-062104210391906
Pubmed

The human mast cell tryptase tetramer: a fascinating riddle solved by structure.

TPSAB1 TPSB2

8.86e-062104210708850
Pubmed

Tryptase haplotype in mastocytosis: relationship to disease variant and diagnostic utility of total tryptase levels.

TPSAB1 TPSB2

8.86e-062104217449330
Pubmed

The tryptase, mouse mast cell protease 7, exhibits anticoagulant activity in vivo and in vitro due to its ability to degrade fibrinogen in the presence of the diverse array of protease inhibitors in plasma.

TPSAB1 TPSD1

8.86e-06210429395536
Pubmed

Impact of naturally forming human α/β-tryptase heterotetramers in the pathogenesis of hereditary α-tryptasemia.

TPSAB1 TPSB2

8.86e-062104231337736
Pubmed

Genetic deficiency of human mast cell alpha-tryptase.

TPSAB1 TPSD1

8.86e-062104212100045
Pubmed

Identification and molecular cloning of a novel mouse mucosal mast cell serine protease.

TPSAB1 TPSD1

8.86e-06210421688433
Pubmed

Lack of expression of the tryptase mouse mast cell protease 7 in mast cells of the C57BL/6J mouse.

TPSAB1 TPSD1

8.86e-06210428077672
Pubmed

Isolation, characterization, and transcription of the gene encoding mouse mast cell protease 7.

TPSAB1 TPSD1

8.86e-06210421454796
Pubmed

Interferon-alpha-induced endogenous superantigen. a model linking environment and autoimmunity.

ERVK-6 ERVK-18

8.86e-062104211672541
Pubmed

Transcriptional regulation of mouse mast cell protease-7 by TGF-beta.

TPSAB1 TPSD1

8.86e-062104216730810
Pubmed

Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

DNAH3 DNAH10 DNAH11

9.23e-061410439373155
Pubmed

A mammalian homolog of Drosophila melanogaster transcriptional coactivator intersex is a subunit of the mammalian Mediator complex.

MED14 MED17 USP47

1.15e-0515104314576168
Pubmed

Mouse models for hereditary spastic paraplegia uncover a role of PI4K2A in autophagic lysosome reformation.

PI4K2A ZFYVE26

2.65e-053104233618608
Pubmed

Increased expression and characterization of two distinct folate binding proteins in murine erythroleukemia cells.

FOLR1 FOLR3

2.65e-05310428304978
Pubmed

Characterization of two cDNAs encoding folate-binding proteins from L1210 murine leukemia cells. Increased expression associated with a genomic rearrangement.

FOLR1 FOLR3

2.65e-05310421894617
Pubmed

Identification of amino acid residues that determine the differential ligand specificities of folate receptors alpha and beta.

FOLR1 FOLR3

2.65e-05310429166787
Pubmed

Identification of an active reverse transcriptase enzyme encoded by a human endogenous HERV-K retrovirus.

ERVK-6 ERVK-9

2.65e-05310429971820
Pubmed

Renal tubular reabsorption of folate mediated by folate binding protein 1.

FOLR1 FOLR3

2.65e-053104215703271
Pubmed

The expression pattern of three mast cell specific proteases during mouse development.

TPSAB1 TPSD1

2.65e-053104216777228
Pubmed

Developmental consequences of in utero sodium arsenate exposure in mice with folate transport deficiencies.

FOLR1 FOLR3

2.65e-053104215694460
Pubmed

Characterization of mouse mast cell protease-8, the first member of a novel subfamily of mouse mast cell serine proteases, distinct from both the classical chymases and tryptases.

TPSAB1 TPSD1

2.65e-05310429541598
Pubmed

Expression patterns of folate binding proteins one and two in the developing mouse embryo.

FOLR1 FOLR3

2.65e-05310429973545
Pubmed

Mice lacking the folic acid-binding protein Folbp1 are defective in early embryonic development.

FOLR1 FOLR3

2.65e-053104210508523
Pubmed

Inhibitory effect of the transcription factor encoded by the mutant mi microphthalmia allele on transactivation of mouse mast cell protease 7 gene.

TPSAB1 TPSD1

2.65e-053104211157480
Pubmed

Protective role of protease-activated receptor-2 in anaphylaxis model mice.

TPSAB1 TPSD1

2.65e-053104238635782
Pubmed

Growing Mouse Oocytes Transiently Activate Folate Transport via Folate Receptors As They Approach Full Size.

FOLR1 FOLR3

5.29e-054104227122634
Pubmed

LRRC8 Proteins Form Volume-Regulated Anion Channels that Sense Ionic Strength.

LRRC8C LRRC8D

5.29e-054104226824658
Pubmed

Murine implantation serine proteinases 1 and 2: structure, function and evolution.

TPSAB1 TPSD1

5.29e-054104216257142
Pubmed

Necdin, a Prader-Willi syndrome candidate gene, regulates gonadotropin-releasing hormone neurons during development.

MAGEL2 MAGED1

5.29e-054104218930956
Pubmed

Identification of two putative novel folate receptor genes in humans and mouse.

FOLR1 FOLR3

5.29e-054104211111049
Pubmed

Role of metazoan mediator proteins in interferon-responsive transcription.

MED14 MED17

5.29e-054104212509459
Pubmed

Linkage analysis of susceptibility to ozone-induced lung inflammation in inbred mice.

TPSAB1 TPSD1

5.29e-05410429398854
Pubmed

Mutations in folate transporter genes and risk for human myelomeningocele.

FOLR1 FOLR3

5.29e-054104228948692
Pubmed

LRRC8A:C/E Heteromeric Channels Are Ubiquitous Transporters of cGAMP.

LRRC8C LRRC8D

5.29e-054104233171122
Pubmed

Association of folate receptor (FOLR1, FOLR2, FOLR3) and reduced folate carrier (SLC19A1) genes with meningomyelocele.

FOLR1 FOLR3

5.29e-054104220683905
Pubmed

Identification, tissue specific expression, and chromosomal localisation of several human dynein heavy chain genes.

DNAH3 DNAH10

5.29e-054104211175280
Pubmed

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.

DNAH3 NTHL1 HSPA12B CCDC17 WNK2 DNAH11

7.44e-05233104637704626
Pubmed

Renal Deletion of LRRC8/VRAC Channels Induces Proximal Tubulopathy.

LRRC8C LRRC8D

8.80e-055104235777784
Pubmed

Genetic linkage analysis of susceptibility to particle exposure in mice.

TPSAB1 TPSD1

8.80e-055104210783129
Pubmed

Transcriptionally active HERV-K genes: identification, isolation, and chromosomal mapping.

ERVK-6 ERVK-7

8.80e-055104211401426
Pubmed

LRRC8 involved in B cell development belongs to a novel family of leucine-rich repeat proteins.

LRRC8C LRRC8D

8.80e-055104215094057
Pubmed

Identification of LRRC8 heteromers as an essential component of the volume-regulated anion channel VRAC.

LRRC8C LRRC8D

8.80e-055104224790029
Pubmed

Pulmonary mastocytosis and enhanced lung inflammation in mice heterozygous null for the Foxf1 gene.

TPSAB1 TPSD1

8.80e-055104218421012
Pubmed

Characterization of human gamma-tryptases, novel members of the chromosome 16p mast cell tryptase and prostasin gene families.

TPSAB1 TPSB2

8.80e-055104210843716
Pubmed

Mast cells contribute to autoimmune inflammatory arthritis via their tryptase/heparin complexes.

TPSAB1 TPSD1

8.80e-055104219109198
Pubmed

Elastase and tryptase govern TNFα-mediated production of active chemerin by adipocytes.

TPSAB1 TPSD1

8.80e-055104223227233
Pubmed

Transcriptional activation of mouse mast cell Protease-7 by activin and transforming growth factor-beta is inhibited by microphthalmia-associated transcription factor.

TPSAB1 TPSD1

8.80e-055104214527958
Pubmed

HSPA12A attenuates lipopolysaccharide-induced liver injury through inhibiting caspase-11-mediated hepatocyte pyroptosis via PGC-1α-dependent acyloxyacyl hydrolase expression.

AOAH HSPA12A

8.80e-055104232332915
Pubmed

The mediator complex functions as a coactivator for GATA-1 in erythropoiesis via subunit Med1/TRAP220.

MED14 MED17

8.80e-055104217132730
Pubmed

A mammalian mediator subunit that shares properties with Saccharomyces cerevisiae mediator subunit Cse2.

MED14 MED17 USP47

8.97e-0529104314638676
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

FAM193B LRWD1 MED14 STK32C EDC4 MST1R THADA DNAJC14 SUMF1 ZFYVE26 MMP17 WNK2

1.17e-0411051041235748872
Pubmed

Two naturally occurring variants of the serotonin receptor gene HTR3C are associated with nausea in pregnancy.

HTR3C TACR1

1.32e-046104220021265
Pubmed

Folate transport in mouse cumulus-oocyte complexes and preimplantation embryos.

FOLR1 FOLR3

1.32e-046104223904512
Pubmed

Genome-wide scan of healthy human connectome discovers SPON1 gene variant influencing dementia severity.

SPON1 TACR1

1.84e-047104223471985
Pubmed

Isolation of several human axonemal dynein heavy chain genes: genomic structure of the catalytic site, phylogenetic analysis and chromosomal assignment.

DNAH3 DNAH11

1.84e-04710429256245
Pubmed

The murine Ten-m/Odz genes show distinct but overlapping expression patterns during development and in adult brain.

TENM1 EN1

1.84e-047104212915301
Pubmed

Location of the mouse mast cell protease 7 gene (Mcpt7) to chromosome 17.

TPSAB1 TPSD1

2.45e-04810427849408
Pubmed

Microarray analysis on Runx2-deficient mouse embryos reveals novel Runx2 functions and target genes during intramembranous and endochondral bone formation.

TPSAB1 TPSD1

2.45e-048104216774856
Pubmed

Spatial and temporal expression of folate-related transporters and metabolic enzymes during mouse placental development.

FOLR1 FOLR3

2.45e-048104222365888
Pubmed

The transcriptional cofactor complex CRSP is required for activity of the enhancer-binding protein Sp1.

MED14 MED17

3.14e-04910429989412
Pubmed

Coordination of p300-mediated chromatin remodeling and TRAP/mediator function through coactivator PGC-1alpha.

MED14 MED17

3.14e-049104214636573
Pubmed

TRAP/SMCC/mediator-dependent transcriptional activation from DNA and chromatin templates by orphan nuclear receptor hepatocyte nuclear factor 4.

MED14 MED17

3.14e-049104212101254
Pubmed

Ligand induction of a transcriptionally active thyroid hormone receptor coactivator complex.

MED14 MED17

3.14e-04910428710870
Pubmed

Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.

DMXL2 CEACAM5 DNAH10 CAPN3 ACVR1B LCK MMP17 WNK2 DNAH11

3.51e-04730104934857952
Pubmed

A coregulatory role for the TRAP-mediator complex in androgen receptor-mediated gene expression.

MED14 MED17

3.92e-0410104212218053
Pubmed

Mouse chromosome 17A3.3 contains 13 genes that encode functional tryptic-like serine proteases with distinct tissue and cell expression patterns.

TPSAB1 TPSD1

3.92e-0410104214583634
Pubmed

Necdin promotes ubiquitin-dependent degradation of PIAS1 SUMO E3 ligase.

MAGEL2 MAGED1

4.79e-0411104224911587
Pubmed

Transcription coactivator TRAP220 is required for PPAR gamma 2-stimulated adipogenesis.

MED14 MED17

4.79e-0411104212037571
GeneFamilyWD repeat domain containing

DMXL2 LRWD1 DCAF8L2 WDR97 WRAP73 DNAI4 ELP2

1.98e-05262587362
GeneFamilyDyneins, axonemal

DNAH3 DNAH10 DNAH11

2.06e-0517583536
GeneFamilyVolume regulated anion channel subunits

LRRC8C LRRC8D

1.01e-0455821158
GeneFamilyHeat shock 70kDa proteins

HSPA12B HSPA12A

1.33e-0317582583
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RGSL1 DNAH10 ABCA13 PKHD1 FUT9 TENM1 WNK2 TMPRSS11A

2.03e-09162948bf886e22ff2a20353499004b53f25fb9e6574896
ToppCellEpithelial-ciliated_cell|World / Lineage, Cell type, age group and donor

DNAH3 DNAH10 ABCA13 MYCBPAP DNAI4 CCDC17 CFAP99 DNAH11

6.56e-0918894861a459f3fe57e5728efc72637ff2edc2d343492b
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RGSL1 ABCA13 PKHD1 FUT9 TENM1 WNK2 TMPRSS11A

2.53e-0814594796712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 DNAH10 ABCA13 MYCBPAP DNAI4 CCDC17 DNAH11

7.24e-0816994714aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 DNAH10 ABCA13 MYCBPAP DNAI4 CCDC17 DNAH11

8.50e-08173947c3762655caa79ac4879876f470d32578a3c93b01
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 DNAH10 ABCA13 DNAI4 MUC4 CCDC17 DNAH11

1.11e-071809471f1af4474f3f0ac3c0d6b1a6c875c354d36d8eec
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DNAH3 DNAH10 DNAI4 MUC4 CCDC17 CFAP99 DNAH11

1.16e-07181947dfce05bd472f67e6e2bb60ebd6fd34f0a9aeeca6
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DNAH3 DNAH10 MYCBPAP DNAI4 CCDC17 CFAP99 DNAH11

1.44e-071879479e10ed56090d82589bc457788282f664b70ace4b
ToppCellAdult-Epithelial-ciliated_cell-D231|Adult / Lineage, Cell type, age group and donor

DNAH3 DNAH10 ABCA13 MYCBPAP DNAI4 CCDC17 DNAH11

1.50e-0718894734b11f72ca73153d02edcd09b38983ad1a504659
ToppCellCOVID-19-lung-Ciliated|COVID-19 / Disease (COVID-19 only), tissue and cell type

DNAH3 DNAH10 ABCA13 MYCBPAP DNAI4 CCDC17 DNAH11

1.55e-07189947a2da5debd10f27b1280b40141ef0bfef007cc72c
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

DNAH3 DNAH10 ABCA13 DNAI4 CCDC17 CFAP99 DNAH11

1.55e-0718994768a3cf7763d6f9b95d6d6524eff7a16042703f1d
ToppCellControl-Epithelial-Ciliated|Control / Disease state, Lineage and Cell class

DNAH3 DNAH10 ABCA13 DNAI4 MUC4 CCDC17 DNAH11

1.55e-07189947c007fccd08728db3ea99af9da91d67b9b16dabb3
ToppCellAdult-Epithelial-ciliated_cell|Adult / Lineage, Cell type, age group and donor

DNAH3 DNAH10 ABCA13 MYCBPAP DNAI4 CCDC17 DNAH11

1.55e-07189947b679920f0993e917dd86da082113bfbd85ea1ca5
ToppCellnucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

DNAH3 DNAH10 ABCA13 DNAI4 MUC4 CCDC17 DNAH11

1.67e-07191947e417bf491f8b8d7838a61f7f4f6b1740ba97aa3f
ToppCellnucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

DNAH3 DNAH10 ABCA13 DNAI4 MUC4 CCDC17 DNAH11

1.67e-071919479d31c8424d35bdc0c27188b68bfd0f731af3600b
ToppCellnucseq-Epithelial-Epithelial_Airway|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

DNAH3 DNAH10 ABCA13 DNAI4 MUC4 CCDC17 DNAH11

1.67e-071919471c528f72c9ef3ef3a850b05e4a9715190832270c
ToppCellCOPD-Epithelial-Ciliated|World / Disease state, Lineage and Cell class

DNAH3 DNAH10 ABCA13 DNAI4 MUC4 CCDC17 DNAH11

1.73e-07192947eab1105cd1a98cfcd3d74dc5c9b89e1799bba59e
ToppCellwk_20-22-Epithelial-Proximal_epithelial-MUC16+_ciliated|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

DNAH3 DNAH10 ABCA13 DNAI4 MUC4 CCDC17 DNAH11

1.85e-07194947756082a0f5953b52229bb60d40b84701cb6cb23d
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 DNAH10 ABCA13 MUC4 CCDC17 CFAP99 DNAH11

1.85e-071949474a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 DNAH10 ABCA13 DNAI4 MUC4 CCDC17 DNAH11

1.92e-0719594779dc031258579ea328181dda33710dd897f1064a
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 DNAH10 ABCA13 DNAI4 MUC4 CCDC17 DNAH11

2.06e-0719794791637bdeab85024b5a02d1066f76cb803a2d6420
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 DNAH10 ABCA13 DNAI4 MUC4 CCDC17 DNAH11

2.06e-0719794722c87dd15dc57bd0aa98a204c9fc9b3b9b573b45
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 DNAH10 ABCA13 DNAI4 MUC4 CCDC17 DNAH11

2.06e-071979473bbf068d2ad8196fbc85d3f311a7c54c9aece856
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 DNAH10 ABCA13 DNAI4 MUC4 CCDC17 DNAH11

2.06e-0719794787db09f341e2b20eb6e1c3e917cb5c960387b3e9
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 CEACAM5 ABCA13 DNAI4 MUC4 CCDC17 DNAH11

2.13e-07198947d0ecace1fad24ce50b0935036fabb07e6c9e372d
ToppCellBronchial-10x5prime-Epithelial-Epi_airway_ciliated-Deuterosomal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

DNAH3 DNAH10 DCST2 MYCBPAP SLC22A2 RECQL4 CCDC17

2.20e-0719994792778939e9d06599c7d06cfd8f4362b97ed0606b
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_ciliated-Ciliated|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DNAH3 DNAH10 ABCA13 MYCBPAP DNAI4 CCDC17 CFAP99

2.28e-07200947926a7ea94b5908aebf103893ea83ce9d25285b65
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_ciliated|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DNAH3 DNAH10 ABCA13 MYCBPAP DNAI4 CCDC17 CFAP99

2.28e-0720094706ce6e03498ba38ef6a06eaf2731e3b2eeda59eb
ToppCell3'-Airway_Nasal-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes-Classical_monocytes_L.1.2.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CYP1B1 DMXL2 AOAH CHD1 CLEC4D MYBPC3

1.95e-06175946cd42020fe57afeaadfbd3ef6d7375e66d71e9669
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA13 SLC12A8 SPON1 FUT9 DNAI4 DNAH11

1.95e-06175946284fdc7a9d303636a637041846850d19d114861a
ToppCellCiliated_cells-B-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

DNAH3 ABCA13 MYCBPAP DNAI4 CCDC17 DNAH11

2.08e-06177946c38138fb5ad9766c2d240811210c854338cd612e
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SGIP1 ABCA13 SPON1 PKHD1 FUT9 DNAH11

2.15e-06178946c20f050344a2e120e685e2a7fe36c6dfc1dc37b6
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 ABCA13 WDR97 MUC4 CCDC17 DNAH11

2.15e-061789463b12db04006db6e94fc45649a4b3a63b92f21a61
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 RGSL1 DNAH10 SLC22A2 MUC4 CCDC17

2.29e-06180946adf5db5bfa9a38b1227ab0beccd8d6f3eea67ac0
ToppCellfacs-GAT-Fat-3m-Epithelial-epithelial_cell|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOLR1 MYCBPAP TM4SF4 PKHD1 WNK2 DNAH11

2.37e-06181946e97cbaafb93fdbee8e3cf4a06e6bcf121d941403
ToppCellfacs-GAT-Fat-3m-Epithelial|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOLR1 MYCBPAP TM4SF4 PKHD1 WNK2 DNAH11

2.37e-0618194611cb84528f7ca084f0a92eda4f2e18e63a428fe9
ToppCell-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

DOK5 TPSAB1 SLC12A8 TPSD1 LOX TMEM151A

2.37e-06181946ef579e958f334da0f9415aa7e3d5c02c807954a6
ToppCellfacs-GAT-Fat-3m-Epithelial-nan|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOLR1 MYCBPAP TM4SF4 PKHD1 WNK2 DNAH11

2.37e-061819465ffeca29e4d31a20c110d27af128ed024a79ad56
ToppCellControl-Epithelial_cells-Airway_ciliated|Control / group, cell type (main and fine annotations)

DNAH3 DNAH10 ABCA13 DNAI4 CCDC17 DNAH11

2.45e-06182946fb725d10d9ed25dfc6d5bb69cfef78513f7d3e8f
ToppCellCiliated_cells-A-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

DNAH3 DNAH10 DNAI4 MUC4 CCDC17 DNAH11

2.60e-0618494607c5a9633ccdcd18771e3230d6198a55c400afa6
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

DNAH3 DNAH10 ABCA13 MYCBPAP CCDC17 DNAH11

2.60e-061849465daff849625f2f41d56615569c0ed59cd733b34c
ToppCelldroplet-Kidney-KIDNEY-1m-Mesenchymal-podocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SGIP1 HSPA12B MYCBPAP SPON1 MMP17 WNK2

2.69e-06185946ca69499ba8c39b7ed6717d05685d6f70066a77bd
ToppCellNS-moderate-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH3 DNAH10 MYCBPAP DNAI4 CCDC17 DNAH11

2.69e-061859465e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCellAdult-Epithelial-ciliated_cell-D175|Adult / Lineage, Cell type, age group and donor

DNAH3 DNAH10 DNAI4 CCDC17 CFAP99 DNAH11

2.69e-0618594630f4980dee6cd5959655f8d74049f3bfb5312611
ToppCellCOVID-19-Epithelial_cells-Airway_ciliated|COVID-19 / group, cell type (main and fine annotations)

DNAH3 DNAH10 ABCA13 DNAI4 CCDC17 DNAH11

2.69e-0618594618a40f0a338aa398d81384b5159fb80ce8a2020c
ToppCellCiliated_cells-B-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

DNAH3 DNAH10 ABCA13 DNAI4 CCDC17 DNAH11

2.77e-06186946f72267d533fd0c5280d9741ceee3dd116300a7e4
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA13 PKHD1 FUT9 TENM1 KAZN DNAH11

2.77e-06186946f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCellCOPD-Epithelial-Ciliated|COPD / Disease state, Lineage and Cell class

DNAH3 DNAH10 ABCA13 DNAI4 MUC4 CCDC17

2.86e-06187946f0fd0792f6926f705d175f6e6fd480f12c7a3bd4
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SGIP1 ABCA13 PKHD1 FUT9 KAZN DNAH11

2.95e-0618894663a4b25a0a6e05f80f1a6dd91b817f3cf49e6b68
ToppCellCiliated_cells-B-Donor_07|World / lung cells shred on cell class, cell subclass, sample id

DNAH3 DNAH10 DNAI4 MUC4 CCDC17 DNAH11

2.95e-06188946606907c865bd2f11bb6474932716550f7723d858
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

DNAH3 DNAH10 ABCA13 DNAI4 CCDC17 DNAH11

2.95e-061889462b6dfc88be9ded7b88da9fe78a9cd9f9b3af8af3
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Ciliated_1|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

DNAH3 DNAH10 MYCBPAP DNAI4 CCDC17 DNAH11

3.04e-06189946dc440015949a768188c67661b6be63b1ead1a0f0
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SGIP1 NAPEPLD ABCA13 PKHD1 FUT9 DNAH11

3.04e-06189946904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SGIP1 ABCA13 SPON1 FUT9 KAZN DNAH11

3.04e-061899461ecf9911ff82e0ca0f0c101b735d3b1f3b339d57
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 DNAH10 ABCA13 SLC22A2 MUC4 CCDC17

3.04e-06189946b4b93bd10b7e3cc16e54ff73beac230f519c010a
ToppCellCOVID-19-lung-Ciliated|lung / Disease (COVID-19 only), tissue and cell type

DNAH3 DNAH10 ABCA13 DNAI4 CCDC17 DNAH11

3.04e-0618994627329c4661aebabd19fac7fe5dca263fe99d76f3
ToppCellCOPD-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

DNAH3 DNAH10 ABCA13 DNAI4 CCDC17 DNAH11

3.04e-061899463e77883db34722b9ce0a03ea74caefc92dc7feff
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SGIP1 ABCA13 PKHD1 FUT9 DNAI4 KAZN

3.23e-06191946d0e9afe7b6334dd515d3e68892efdc76347a55e5
ToppCellwk_15-18-Epithelial-Proximal_epithelial-MUC16+_ciliated|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

DNAH3 DNAH10 ABCA13 MUC4 CCDC17 DNAH11

3.23e-06191946e81cd65dbf0ef1c2ab7088f73ce605d456dd3a7a
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 DNAH10 ABCA13 DNAI4 CCDC17 DNAH11

3.43e-06193946e1b76102f812c433195d1e8811fdd3293a7bc22e
ToppCellControl-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

DNAH3 DNAH10 ABCA13 DNAI4 CCDC17 DNAH11

3.43e-061939460e37d454f3735edd936ee9a5f5f516ac3aad400e
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA13 SPON1 SLC22A2 PKHD1 FUT9 DNAH11

3.43e-06193946ffa1932da2979d7b63dbac32eb5788346a3f5b2a
ToppCellControl-Epithelial-Ciliated|World / Disease state, Lineage and Cell class

DNAH3 DNAH10 ABCA13 DNAI4 CCDC17 DNAH11

3.53e-06194946958e648138676d46698090b4046cb484083ae449
ToppCellCOVID-19-Epithelial-Ciliated_cells|COVID-19 / Condition, Lineage and Cell class

DNAH3 DNAH10 ABCA13 MUC4 CCDC17 DNAH11

3.53e-0619494643be5fbd51dd58839cb03ca3ddd05a458e1ddb74
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 DNAH10 ABCA13 DNAI4 CCDC17 DNAH11

3.64e-06195946649fd2336e963f6a150d182a53ad5dd838ca80b1
ToppCellNS-critical-LOC-Epithelial-Ciliated|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH3 DNAH10 ABCA13 DNAI4 CCDC17 DNAH11

3.64e-0619594634e37cff4849696ca4ba5dd8fd2cf98fed8bc912
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 DNAH10 ABCA13 DNAI4 CCDC17 DNAH11

3.64e-06195946129ad5f4253ecb1a8477cc38773e6e91ea9570b0
ToppCell10x5'v1-week_12-13-Myeloid_neutrophil-granulo-neutrophil|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

CYP1B1 DMXL2 ABCA13 FOLR3 CAPN3 CLEC4D

3.64e-06195946fb3dc2c8fd125f23d0c3aa211520778aac8d6dda
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 DNAH10 ABCA13 DNAI4 CCDC17 DNAH11

3.64e-061959463e70ee987d66d450062d5df3d7c733ccc7344470
ToppCellCOPD-Multiplet-Multiplet|COPD / Disease state, Lineage and Cell class

DNAH3 ABCA13 DNAI4 MUC4 TPSB2 DNAH11

3.75e-06196946af4cdc61830685a888a1209826c23bcf54a43084
ToppCellCOPD-Multiplet|COPD / Disease state, Lineage and Cell class

DNAH3 ABCA13 DNAI4 MUC4 TPSB2 DNAH11

3.75e-061969466d02d494196e3f857d53eea46d9419690d43beca
ToppCellGoblet_cell|World / shred on cell type and cluster

CEACAM5 MAGED1 REG4 SLC12A8 ASPH MUC4

3.86e-06197946d82d3204f24c95771c1496c28e3fbc6e2442199b
ToppCellC_04|World / shred on cell type and cluster

CEACAM5 MAGED1 REG4 SLC12A8 ASPH MUC4

3.86e-06197946885604356e19a850b0e601c3167ad26b8180bcec
ToppCellCOVID-19-Epithelial|COVID-19 / Condition, Lineage and Cell class

DNAH3 DNAH10 ABCA13 MUC4 CCDC17 DNAH11

3.86e-0619794618fd7344628a87d5c7ef5efb66e260a4136245bf
ToppCelldistal-Epithelial-Ciliated-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

DNAH3 DNAH10 DNAI4 MUC4 CCDC17 DNAH11

4.09e-061999462de1fe124737a6cca4b3805ab3056f9d9d7c16c7
ToppCell3'_v3-Lung-Myeloid_Monocytic|Lung / Manually curated celltypes from each tissue

CYP1B1 FOLR3 ETS2 CHD1 PPM1F ASPH

4.09e-061999463e14f9a62d6414add8d5f681be184b4625001838
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_ciliated|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DNAH3 DNAH10 ABCA13 MYCBPAP CCDC17 CFAP99

4.09e-061999462498237b9e895ca4826a3378d9d40989968df72b
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_ciliated-Ciliated|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DNAH3 DNAH10 ABCA13 MYCBPAP CCDC17 CFAP99

4.09e-06199946542ec45c931b40738df1f3777b00c83be33a514a
ToppCellBiopsy_Other_PF-Epithelial-Differentiating_Ciliated|Biopsy_Other_PF / Sample group, Lineage and Cell type

DNAH10 ABCA13 DNAI4 MUC4 CCDC17 DNAH11

4.21e-06200946f7b4581d958afbd68f9045af619aaca0ab463439
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

DNAH3 DNAH10 MYCBPAP DNAI4 CCDC17 DNAH11

4.21e-0620094631d75c26055177d656df1fbb10b764cebd61e122
ToppCellBronchus_Control_(B.)-Epithelial-TX-Club|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

CEACAM5 ABCA13 FOLR1 NTHL1 MUC4 WNK2

4.21e-06200946292c63693eb7f435335a8cfba07aa35b72139393
ToppCellBiopsy_Control_(H.)-Epithelial-Differentiating_Ciliated|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

DNAH3 DNAH10 ABCA13 DNAI4 MUC4 WNK2

4.21e-06200946a552a99f5e4fa00dfb7775e5a3e1f62f1530d104
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_ciliated-Ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

DNAH3 DNAH10 MYCBPAP DNAI4 CCDC17 DNAH11

4.21e-06200946e1dce91c6c531bb212002a14705e496d77ad3490
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-Ciliated|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DNAH3 DNAH10 ABCA13 DNAI4 CCDC17 DNAH11

4.21e-06200946f1a49bc818054fb0734d3b84725ee6487b034567
ToppCellParenchyma_COVID-19-Epithelial-TX-Club|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

CEACAM5 ABCA13 FOLR1 TACR1 MUC4 WNK2

4.21e-0620094685f946dd3831acf3488c87efba96689cc2667c3a
ToppCellParenchyma_COVID-19-Epithelial-TX-Ciliated|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

DNAH3 DNAH10 ABCA13 DNAI4 CCDC17 DNAH11

4.21e-06200946d7ae09189cf0b7e2f7e7fc6b0921975b75aa7d62
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-Ciliated|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

DNAH3 DNAH10 ABCA13 DNAI4 CCDC17 DNAH11

4.21e-06200946ddd39b754bfaa98249d497dfb7e97ec58617a11a
ToppCellBiopsy_IPF-Epithelial|Biopsy_IPF / Sample group, Lineage and Cell type

DNAH10 FOLR1 DNAI4 MUC4 CCDC17 DNAH11

4.21e-0620094676f1ac00b34d07057d8da03d276438b719b46b1d
ToppCellParenchyma_Control_(B.)-Epithelial-TX-Ciliated|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

DNAH3 DNAH10 ABCA13 DNAI4 CCDC17 DNAH11

4.21e-06200946a521cf837cadf280505ff9d7e641a205af7d6513
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-Ciliated-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DNAH3 DNAH10 ABCA13 DNAI4 CCDC17 DNAH11

4.21e-06200946918b576fd9491d23c2bb9d663fa5fb3505cb1c7e
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-Club-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CEACAM5 ABCA13 FOLR1 TACR1 MUC4 WNK2

4.21e-062009468a44a4f7ea9358f2194a490e79601c98ff7fdcb0
ToppCellBiopsy_IPF-Mesenchymal-HAS1_High_Fibroblasts|Biopsy_IPF / Sample group, Lineage and Cell type

DOK5 CYP1B1 PAMR1 SLC12A8 LOX SPON1

4.21e-06200946d02e256b5d65a5c982ba5696bc7e077281ca3e24
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-Club|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

CEACAM5 ABCA13 FOLR1 TACR1 MUC4 WNK2

4.21e-0620094630d428510c68da96c7c8cfd472f449ebb9631132
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-Ciliated-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DNAH3 DNAH10 ABCA13 DNAI4 CCDC17 DNAH11

4.21e-06200946cf59110547cc66b5f4a2999735336b0309ba9b0d
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Granulocytic-Neutrophil-Neu_c1-IL1B|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CYP1B1 DMXL2 CLEC4D MUC4 MYBPC3

1.72e-051519457b50425d2bbd7b6ff2a6e67d3e2470a4455740e0
ToppCellCOVID-19-Epithelial_cells-Airway_mucous|COVID-19 / group, cell type (main and fine annotations)

DNAH3 DNAH10 ABCA13 DNAI4 DNAH11

1.72e-051519458216462e723fec2797387929dde095370947e10a
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid-Granulocytic|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TPSAB1 FOLR3 TPSD1 MPP4 TPSB2

1.83e-0515394583942ef63d21725fa15ed5a91481d1f9936e8f11
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SGIP1 ABCA13 PKHD1 FUT9 DNAH11

2.14e-051589451cefb82b9bf79c687a119be568cfc15b14c6e040
ToppCellCiliated_cells-B-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

DNAH3 ABCA13 MYCBPAP DNAI4 CCDC17

2.56e-051649450e9961acbb1d6c0089e6805ba6756736fa4d8bed
ToppCellMultiple_Sclerosis-Other-HSPC|Multiple_Sclerosis / Disease, Lineage and Cell Type

DOK5 TPSAB1 SGIP1 TPSD1 TPSB2

2.56e-051649456af5529507d695b347adee4be5ead70f56c9cf55
DrugBrunfelsamidine

TPSAB1 TPSD1 TPSB2

2.81e-074953CID005281683
Drugioxaglate

TPSAB1 TPSD1 TPSB2

2.43e-067953CID000003742
DrugTelebrix

TPSAB1 TPSD1 TPSB2

2.43e-067953CID000034536
Drugdaphnodorin C

TPSAB1 TPSD1 TPSB2

5.80e-069953CID000072428
DrugAC1NUP69

TPSAB1 TPSD1 TPSB2

8.27e-0610953CID005487154
Drug1c5s

TPSAB1 TPSD1 TPSB2

8.27e-0610953CID000444753
Drugpimaradiene

TPSAB1 TPSD1 TPSB2

1.13e-0511953CID000440909
DrugZ-ala-ala-lys-mna

TPSAB1 TPSD1 TPSB2

1.13e-0511953CID005486901
Drugdaphnodorin A

TPSAB1 TPSD1 TPSB2

1.13e-0511953CID000072426
DrugAC1NSU64

TPSAB1 TPSD1 TPSB2

1.13e-0511953CID005316303
Drugmethylhistamine

TPSAB1 TPSD1 TPSB2

1.13e-0511953CID000000912
Drugbis(5-amidino-2-benzimidazolyl)methane

TPSAB1 TPSD1 TPSB2

1.51e-0512953CID000002386
DrugElocom

TPSAB1 TPSD1 TPSB2

1.51e-0512953CID000123620
Drug4-amidinophenylpyruvic acid

TPSAB1 TPSD1 TPSB2

1.51e-0512953CID000151496
DrugNSC-648146

TPSAB1 TPSD1 TPSB2

1.51e-0512953CID000372649
DrugTrazodone hydrochloride [25332-39-2]; Up 200; 9.8uM; MCF7; HT_HG-U133A

AOAH PI4K2A ETS2 SLC12A8 CRY2 HSPA12A KAZN

1.72e-051949577410_UP
DrugAC1NUV1X

ERVK-6 LCK

1.72e-052952CID005494401
DrugProtriptyline hydrochloride [1225-55-4]; Down 200; 13.4uM; HL60; HT_HG-U133A

CYP1B1 CAPN3 ETS2 MED14 ACVR1B KAZN IKBKB

1.78e-051959573119_DN
DrugZ-ARR-AFC

TPSAB1 TPSD1 TPSB2

1.95e-0513953CID000125067
DrugNk3201

TPSAB1 TPSD1 TPSB2

1.95e-0513953CID000213050
Drug2-Chloropyrazine [14508-49-7]; Down 200; 35uM; PC3; HT_HG-U133A

DOK5 CEACAM5 PI4K2A SLC12A8 ACVR1B DNAI4 EN1

2.09e-052009575750_DN
DrugArtemisinin [63968-64-9]; Up 200; 14.2uM; MCF7; HT_HG-U133A

DOK5 FOLR1 CRY2 PPM1F FUT9 ZFYVE26 IKBKB

2.09e-052009577007_UP
DrugABPH

TPSAB1 TPSD1 TPSB2

2.48e-0514953CID000092377
DrugAa1

TPSAB1 TPSD1 LOX IKBKB TPSB2

2.55e-0583955CID009549188
DrugFdTTP

TPSAB1 TPSD1 TPSB2

3.09e-0515953CID000162005
Drugthymidine glycol

TPSAB1 NTHL1 TPSB2

3.79e-0516953CID003035041
Drug(E)-4-aminohex-4-enoic acid

TPSAB1 TPSD1 TPSB2

3.79e-0516953CID005288385
Drugmethylimidazoleacetic acid

TPSAB1 TPSD1 TPSB2

4.59e-0517953CID000075810
DrugH 17

TPSAB1 TPSD1 TPSB2

4.59e-0517953CID000476867
Drugthymidine glycol monophosphate

TPSAB1 TPSB2

5.15e-053952CID000165415
Drug2D7

TPSAB1 TPSD1 CLEC4D TPSB2

5.22e-0549954CID005327103
Drug2-azetidinone

TPSAB1 TPSD1 TPSB2

5.49e-0518953CID000136721
DrugA80a

TPSAB1 TPSD1 TPSB2

7.62e-0520953CID005487000
Drug4-oh-8-o-2'dg

CYP1B1 NTHL1 RECQL4

7.62e-0520953CID000126256
DrugAC1L1E6H

CYP1B1 HSPA12B HSPA12A IKBKB

7.67e-0554954CID000002661
DrugAC1LTNWX

TPSAB1 TPSD1 CLEC4D TPSB2

1.02e-0458954CID001536427
Drugatracurium besylate

TPSAB1 TPSD1 TPSB2

1.02e-0422953CID000047320
DrugKinetensin

TPSAB1 TPSD1 TPSB2

1.17e-0423953CID000147043
Drugfenpropathrin

TPSAB1 TPSD1 PKHD1 TPSB2

1.32e-0462954CID000047326
DrugPL 0

TPSAB1 TPSD1 TPSB2

1.34e-0424953CID000016157
DrugS)-bromoenol lactone

TPSAB1 NAPEPLD TPSD1 LOX TPSB2

1.43e-04119955CID000002445
DrugCAS 79547-78-7

TPSAB1 TPSD1 TPSB2

1.51e-0425953CID000003915
DrugCAS 83919-23-7

TPSAB1 TPSD1 TPSB2

1.71e-0426953CID000004240
Drugtetrachlorophthalimide

ERVK-6 CAPN3

1.71e-045952CID000074077
Drug7-CEGua

ERVK-6 CEACAM5

1.71e-045952CID000150878
DrugA821880

CYP1B1 CAPN3

1.71e-045952CID005040205
DrugChloroquine diphosphate [50-63-5]; Down 200; 7.8uM; PC3; HT_HG-U133A

CYP1B1 FAM193B MST1R THADA CCSER2 EN1

1.83e-041989567251_DN
DrugZimelidine dihydrochloride monohydrate [61129-30-4]; Up 200; 9.8uM; PC3; HT_HG-U133A

HSPA12A ASPH TACR1 IKBKB MUC4 MYBPC3

1.83e-041989564609_UP
DrugRicinine [524-40-3]; Up 200; 24.4uM; HL60; HT_HG-U133A

CYP1B1 PI4K2A ACVR1B LOX TM4SF4 EN1

1.83e-041989562505_UP
DrugScopolamine hydrochloride [55-16-3]; Up 200; 11.8uM; HL60; HT_HG-U133A

SLC12A8 ACVR1B MST1R ASPH TACR1 EN1

1.83e-041989563018_UP
DrugEtidronic acid, disodium salt [7414-83-7]; Up 200; 16uM; HL60; HT_HG-U133A

MED14 SLC12A8 ACVR1B SPON1 DNAI4 EN1

1.88e-041999562985_UP
Drugestradiol, USP; Down 200; 0.01uM; MCF7; HT_HG-U133A

REX1BD ETS2 ACVR1B PPM1F CCSER2 ZFYVE26

1.88e-041999567000_DN
Drug2-methylundecanal

TPSAB1 TPSD1 TPSB2

1.91e-0427953CID000061031
DrugProcaine hydrochloride [51-05-8]; Up 200; 14.6uM; PC3; HT_HG-U133A

DOK5 ACVR1B LOX SPON1 TENM1 MYBPC3

1.94e-042009566329_UP
Diseasetryptase beta-2 measurement

TPSAB1 TPSD1 TPSB2

2.51e-069933EFO_0008306
DiseaseOsteosarcoma

FOLR1 MST1R LOX RECQL4

1.49e-0547934C0029463
DiseaseColorectal Carcinoma

CYP1B1 DNAH3 ABCA13 NTHL1 HTR3C CHD1 STK32C PPM1F PKHD1 TENM1

7.46e-057029310C0009402
DiseaseCombined immunodeficiency

LCK RECQL4 IKBKB

2.96e-0441933C0494261
Diseasehip bone mineral density

PAMR1 HSPA12A SPON1 DNAH11

6.90e-04126934EFO_0007702
Diseasebasophil measurement

TPSAB1 THADA TPSB2

9.11e-0460933EFO_0803539
Diseaseglucose measurement

SGIP1 CRY2 THADA KDM4A USP47 MYBPC3

1.30e-03380936EFO_0004468
Diseaseurticaria

TPSAB1 TPSB2

1.80e-0320932EFO_0005531
Diseasesystemic mastocytosis

TPSAB1 TPSD1

2.81e-0325932MONDO_0016586
DiseaseImpaired glucose tolerance

CYP1B1 IKBKB

2.81e-0325932C0271650
Diseasevisuospatial function measurement

PAMR1 WRAP73

3.04e-0326932EFO_0803533

Protein segments in the cluster

PeptideGeneStartEntry
ERKWEVPLLPQNGFW

BTN2A3P

376

Q96KV6
GIAAKWWNPPQEKTI

AKAP2

236

Q9Y2D5
LQVWQGLAWARAPQP

CCDC17

476

Q96LX7
VVCDQKLRPNIPNWW

ACVR1B

446

P36896
KLRPNIPNWWQSYEA

ACVR1B

451

P36896
WWVNNQSLPVSPRLQ

CEACAM5

356

P06731
RWPLVIDPQQQGIKW

DNAH11

3491

Q96DT5
WKLQSLLQNLPQWPA

ABCA13

426

Q86UQ4
MDLVWDNPFINWNPK

HTR3C

91

Q8WXA8
NVNGLKAQPWWTPKE

ASPH

566

Q12797
NTVPPVLNDWKCVWQ

DMXL2

151

Q8TDJ6
PWWQVFNDDLTKPII

CCNQ

216

Q8N1B3
TNPEQIKQWRKNLWI

CHD1

1466

O14646
PPEDWPALIWQQQRE

EDC4

946

Q6P2E9
LQAPTQILKWPQPWA

LRWD1

596

Q9UFC0
QILKWPQPWALGQVV

LRWD1

601

Q9UFC0
EWQKRGGQPWQLIEP

AOAH

511

P28039
KENWIDPLMRWQPEV

CFAP99

146

D6REC4
QRPWQLAQELEPQSW

MUC4

4636

Q99102
WGWLELPWVKQNINR

DNAJC14

396

Q6Y2X3
NIDPVVWTNQRVLKW

KAZN

606

Q674X7
AWQNPVAWQNPVIWP

MAGED1

331

Q9Y5V3
VAWQNPVIWPNPVIW

MAGED1

336

Q9Y5V3
PRPWENLNLSDWEVQ

MAGEL2

911

Q9UJ55
PFLPNWQPVQWHSKV

IKBKB

221

O14920
PQQARPPFQKWIWMN

FUT9

121

Q9Y231
KVIVWDWVRQRPVLN

DCAF8L2

251

P0C7V8
WVQPWRCTLQPVLEN

PNMA6E

301

A0A0J9YXQ4
WWAVAPENKVIGQQP

CSNKA2IP

576

A0A1B0GTH6
RLGIPKNPWLWSEQQ

ETS2

96

P15036
QKAQEEPQWVPATWI

MPP4

616

Q96JB8
WAKPLSQLWQNRPPN

KDM4A

636

O75164
SRPCQTQKPQKPWWE

LCK

221

P06239
LWDVQNPRVKLISWP

DOK5

166

Q9P104
PNLGPWIRQVNQSWR

FOLR3

111

P41439
NAWRPQVNNPKEWLQ

F8

2236

P00451
VKFQPSLWPWDSVRN

MED17

86

Q9NVC6
DVRWVITVPAIWKQP

HSPA12A

196

O43301
VRWVLTVPAIWKQPA

HSPA12B

201

Q96MM6
IPWSPNRQWDEQLDP

HELZ

626

P42694
VVKTDSQQPLVWPAW

EN1

261

Q05925
PWIQQLKFWLGQQRC

MED14

491

O60244
WAWLPQAKVPFSQEI

PI4K2A

366

Q9BTU6
FWNPTPDIKQWRLIR

OSBPL8

656

Q9BZF1
QPQEGFWKRPPQRWS

CCSER2

586

Q9H7U1
QIPWDRNPEALAKWA

CRY2

336

Q49AN0
KVPRNHWVLQWPGQV

DNAH3

1271

Q8TD57
WRNWPGEAKARPQEQ

FAM193B

796

Q96PV7
AERQLQVQWEPPGSW

EBI3

141

Q14213
PAAPGAWRQQIQWEN

LOX

36

P28300
PQKHLGPVWQLQWIE

DNAI4

581

Q5VTH9
WLTRILKPWPMVNQA

FBXO47

236

Q5MNV8
WQINNQEKSWQRPPL

FOXR2

181

Q6PJQ5
FVNQWSVNHDPLKWP

CYP1B1

421

Q16678
WLAAAQRKDPEQAWL

DCST2

666

Q5T1A1
HLWKQNTVNPREWTP

ELP2

366

Q6IA86
VKLVRLRNPWGQVEW

CAPN3

351

P20807
NKRNQWVPWSKLVPE

DNAH10

2401

Q8IVF4
QWEIFPPQSWKLALV

SLC25A35

196

Q3KQZ1
QQDALAQPQPWWKTQ

SLC12A8

16

A0AV02
WCIPESPRWLISQNK

SLC22A2

281

O15244
PNLGPWIQQVDQSWR

FOLR1

111

P15328
NDIQPTYRILKPWWD

LRRC8D

11

Q7L1W4
NRLWEVAGQWQKQVP

PPM1F

131

P49593
NITAPKTQGLRWPWQ

PAMR1

451

Q6UXH9
PIWIGLHDPQKRQQW

REG4

91

Q9BYZ8
QWSLWPEIPCNLIAK

RGSL1

46

A5PLK6
KAQWPAWQPLNVRAA

SPON1

286

Q9HCB6
EAPRSKWPWQVSLRV

TPSAB1

36

Q15661
EAPRSKWPWQVSLRV

TPSB2

36

P20231
GQEAPRSKWPWQVSL

TPSD1

41

Q9BZJ3
CPNVSLQKLPEQWLW

THADA

1126

Q6YHU6
QAPAPTKWNKRNLSW

MMP17

126

Q9ULZ9
KRRWNEEPWESPAQV

RECQL4

261

O94761
PLKVPVWEPQDWQQQ

NTHL1

81

P78549
EPNQFVQPAWQIVLW

TACR1

21

P25103
PEKRTLWLPWNQFIV

TENM1

946

Q9UKZ4
NIPNAVWVWDIQKLR

WRAP73

351

Q9P2S5
EPNQWPQEPWHKVRN

PKHD1

3251

P08F94
RLQQAPPCVWWKATS

TMEM151A

141

Q8N4L1
QQAVAAAPWWLPVKG

SUMF1

171

Q8NBK3
SIIALNQWPKNWPKQ

ERVK-9

811

P63128
VRSQPRPLFQWSKWK

STK32C

51

Q86UX6
KGQWRWVDQTPFNPR

CLEC4D

151

Q8WXI8
VSIIALNQWPKNWPK

ERVK-9

31

P63127
VSIIALNQWPKNWPK

ERVK-24

31

P63129
WPWKDAPIRTLVQRI

REX1BD

31

Q96EN9
PPAVWNAEQQRILWK

SGIP1

741

Q9BQI5
VSIIALNQWPKNWPK

HERVK_113

31

P63121
LWRPRPSQTQWQRKL

WDR97

1071

A6NE52
QSPWEIAAQWVVPRE

FAM20B

61

O75063
VSIIALNQWPKNWPK

ERVK-7

31

P63131
DLDWNPKVSTLNVWP

USP47

1291

Q96K76
VSIIALNQWPKNWPK

ERVK-6

31

Q9Y6I0
VSIIALNQWPKNWPK

ERVK-25

31

P63125
WAPPPQHNFLKNWQR

MYCBPAP

196

Q8TBZ2
PNWSILPEEERNIQW

TBCC

331

Q15814
VSIIALNQWPKNWPK

ERVK-10

31

P10265
VSIIALNQWPKNWPK

ERVK-18

31

P63123
WRRERIWPALQPKEQ

WNK2

541

Q9Y3S1
VSIIALNQWPKNWPK

ERVK-8

31

P63122
NPQRVAWVWLLVLEK

ZFYVE26

71

Q68DK2
WWRRKQLVLPPNLND

MST1R

981

Q04912
ALWNKCREPLNVVPW

TM4SF4

141

P48230
VSIIALNQWPKNWPK

ERVK-21

31

P63119
IQWLKAVQRDNWTPT

THAP4

36

Q8WY91
VIAPKAAWPWQASLQ

TMPRSS11A

191

Q6ZMR5
VSIIALNQWPKNWPK

HERV-K104

31

P63124
VSIIALNQWPKNWPK

ERVK-19

31

P63120
SEQQPAFRVLKPWWD

LRRC8C

11

Q8TDW0
TWKNPSIPNVLRWLI

NAPEPLD

71

Q6IQ20
DAWGLNVALEWKPPQ

MYBPC3

1076

Q14896