Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyCellularComponent	nuclear RNA-directed RNA polymerase complex	ZNFX1 TENT2	1.34e-05	2	77	2	GO:0031380
GeneOntologyCellularComponent	RNA-directed RNA polymerase complex	ZNFX1 TENT2	4.01e-05	3	77	2	GO:0031379
Domain	LIM1_prickle	PRICKLE3 PRICKLE2	1.81e-05	2	80	2	IPR033725
Domain	LIM3_prickle	PRICKLE3 PRICKLE2	5.42e-05	3	80	2	IPR033727
Domain	LIM2_prickle	PRICKLE3 PRICKLE2	5.42e-05	3	80	2	IPR033726
Domain	PET_prickle	PRICKLE3 PRICKLE2	5.42e-05	3	80	2	IPR033723
Domain	PKNOX/Meis_N	MEIS3 MEIS1	1.80e-04	5	80	2	IPR032453
Domain	Meis_PKNOX_N	MEIS3 MEIS1	1.80e-04	5	80	2	PF16493
Domain	PET	PRICKLE3 PRICKLE2	2.69e-04	6	80	2	PF06297
Domain	PET_domain	PRICKLE3 PRICKLE2	2.69e-04	6	80	2	IPR010442
Domain	PET	PRICKLE3 PRICKLE2	2.69e-04	6	80	2	PS51303
Domain	ARM-type_fold	KPNA7 DOCK11 INTS1 ZNFX1 CTNND2 MEI1 WDFY4	6.23e-04	339	80	7	IPR016024
Domain	ATPase_dyneun-rel_AAA	MDN1 DNAH9	1.59e-03	14	80	2	IPR011704
Domain	AAA_5	MDN1 DNAH9	1.59e-03	14	80	2	PF07728
Domain	CRAL/TRIO_N_dom	MEIS3 CLVS1	1.83e-03	15	80	2	IPR011074
Domain	Homeobox_KN	MEIS3 MEIS1	2.36e-03	17	80	2	PF05920
Domain	Homeobox_KN_domain	MEIS3 MEIS1	2.36e-03	17	80	2	IPR008422
Domain	RhoGAP	ARAP3 MYO9A ARHGAP30	2.39e-03	62	80	3	SM00324
Domain	RhoGAP	ARAP3 MYO9A ARHGAP30	2.50e-03	63	80	3	PF00620
Domain	RHOGAP	ARAP3 MYO9A ARHGAP30	2.61e-03	64	80	3	PS50238
Domain	RhoGAP_dom	ARAP3 MYO9A ARHGAP30	2.61e-03	64	80	3	IPR000198
Domain	-	ARAP3 MYO9A ARHGAP30	2.61e-03	64	80	3	1.10.555.10
Domain	P-loop_NTPase	ORC5 DDX17 MDN1 MYO9A NLRP1 ZNFX1 RASL10B DNAH9 URGCP DDX5	3.27e-03	848	80	10	IPR027417
Domain	DEP	DEPDC5 PREX1	3.96e-03	22	80	2	PF00610
Domain	DEP	DEPDC5 PREX1	3.96e-03	22	80	2	PS50186
Domain	DEP	DEPDC5 PREX1	3.96e-03	22	80	2	SM00049
Domain	DEP_dom	DEPDC5 PREX1	4.32e-03	23	80	2	IPR000591
Domain	-	ORC5 DDX17 MDN1 NLRP1 ZNFX1 RASL10B DNAH9 URGCP DDX5	4.54e-03	746	80	9	3.40.50.300
Domain	Rho_GTPase_activation_prot	ARAP3 MYO9A ARHGAP30	6.39e-03	88	80	3	IPR008936
Domain	Arm	KPNA7 CTNND2	7.77e-03	31	80	2	PF00514
Domain	DEAD_ATP_HELICASE	DDX17 DDX5	7.77e-03	31	80	2	PS00039
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	MDN1 CEP89 DOCK11 MYO9A MPDZ CGNL1 ARHGEF4 STIL SPECC1 CSPP1 DCAF7	4.44e-06	861	80	11	36931259
Pubmed	Activation of hypoxia-inducible factor-1 ameliorates postischemic renal injury via inducible nitric oxide synthase.	HIF1A NOS2	5.23e-06	2	80	2	21755458
Pubmed	[Effects of hypoxia inducible factor-1 α siRNA on inducible nitric oxide synthase expression in HaCaT cells].	HIF1A NOS2	5.23e-06	2	80	2	22086003
Pubmed	Helicases DDX5 and DDX17 promote heterogeneity in HBV transcription termination in infected human hepatocytes.	DDX17 DDX5	5.23e-06	2	80	2	38782119
Pubmed	Expression of NOS and HIF-1alpha in human colorectal carcinoma and implication in tumor angiogenesis.	HIF1A NOS2	5.23e-06	2	80	2	16937436
Pubmed	Role of Hypoxia Inducible Factor-1α (HIF-1α) in Innate Defense against Uropathogenic Escherichia coli Infection.	HIF1A NOS2	5.23e-06	2	80	2	25927232
Pubmed	Identification of novel pathway partners of p68 and p72 RNA helicases through Oncomine meta-analysis.	DDX17 DDX5	5.23e-06	2	80	2	18005418
Pubmed	The highly related DEAD box RNA helicases p68 and p72 exist as heterodimers in cells.	DDX17 DDX5	5.23e-06	2	80	2	12595555
Pubmed	Upregulation of DEAD box helicase 5 and 17 are correlated with the progression and poor prognosis in gliomas.	DDX17 DDX5	5.23e-06	2	80	2	32008867
Pubmed	[Expression and significance of HIF-1alpha and iNOS in human middle ear cholesteatoma epithelium].	HIF1A NOS2	5.23e-06	2	80	2	17650819
Pubmed	The Ddx5 and Ddx17 RNA helicases are cornerstones in the complex regulatory array of steroid hormone-signaling pathways.	DDX17 DDX5	5.23e-06	2	80	2	24275493
Pubmed	Involvement of RNA helicases p68 and p72 in colon cancer.	DDX17 DDX5	5.23e-06	2	80	2	17699760
Pubmed	Mycobacterium tuberculosis-infected alveolar epithelial cells modulate dendritic cell function through the HIF-1α-NOS2 axis.	HIF1A NOS2	5.23e-06	2	80	2	32557929
Pubmed	Expression of human inducible nitric oxide synthase in response to cytokines is regulated by hypoxia-inducible factor-1.	HIF1A NOS2	5.23e-06	2	80	2	30391674
Pubmed	The roles of DEAD box helicases in the life cycle of HIV-1.	DDX17 DDX5	5.23e-06	2	80	2	26312911
Pubmed	Chronic hypoxia of endothelial cells boosts HIF-1α-NLRP1 circuit in Alzheimer's disease.	HIF1A NLRP1	5.23e-06	2	80	2	37245530
Pubmed	[Expression of iNOS and HIF-1α with angiogenesis in affected skin biopsies from patients with psoriasis].	HIF1A NOS2	5.23e-06	2	80	2	20871160
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	MDN1 ZBED4 DOCK11 VPS13C INTS1 PRICKLE2 RNASE12 REV3L SDHA DDX5	7.35e-06	736	80	10	29676528
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	ARAP3 MDN1 ZBED4 UBE3B INTS1 DEPDC5 SMG5 ARHGEF4 REV3L NPHP4 PREX1 SDHA	8.21e-06	1105	80	12	35748872
Pubmed	Nitric Oxide Modulates Macrophage Responses to Mycobacterium tuberculosis Infection through Activation of HIF-1α and Repression of NF-κB.	HIF1A NOS2	1.57e-05	3	80	2	28754681
Pubmed	ω-Alkynyl arachidonic acid promotes anti-inflammatory macrophage M2 polarization against acute myocardial infarction via regulating the cross-talk between PKM2, HIF-1α and iNOS.	HIF1A NOS2	1.57e-05	3	80	2	28964797
Pubmed	Acceleration of chronic myeloproliferation by enforced expression of Meis1 or Meis3 in Icsbp-deficient bone marrow cells.	MEIS3 MEIS1	1.57e-05	3	80	2	18223676
Pubmed	Meis1 regulates the metabolic phenotype and oxidant defense of hematopoietic stem cells.	HIF1A MEIS1	1.57e-05	3	80	2	22995899
Pubmed	Nitric oxide causes macrophage migration via the HIF-1-stimulated small GTPases Cdc42 and Rac1.	HIF1A NOS2	1.57e-05	3	80	2	19523512
Pubmed	The DEAD-box protein p72 regulates ERalpha-/oestrogen-dependent transcription and cell growth, and is associated with improved survival in ERalpha-positive breast cancer.	DDX17 DDX5	1.57e-05	3	80	2	19718048
Pubmed	Dual role of the ddx5/ddx17 RNA helicases in the control of the pro-migratory NFAT5 transcription factor.	DDX17 DDX5	1.57e-05	3	80	2	22266867
Pubmed	Polymorphisms in oxidative pathway related genes and susceptibility to inflammatory bowel disease.	HIF1A NOS2	1.57e-05	3	80	2	29307990
Pubmed	The p68 and p72 DEAD box RNA helicases interact with HDAC1 and repress transcription in a promoter-specific manner.	DDX17 DDX5	1.57e-05	3	80	2	15298701
Pubmed	[Role of hypoxia-inducible factor-1α endothelin-1 and inducible nitric oxide synthase in the pathogenesis of hypoxia-induced pulmonary hypertension of the newborn].	HIF1A NOS2	1.57e-05	3	80	2	21251377
Pubmed	Ethanol and tobacco smoke increase hepatic steatosis and hypoxia in the hypercholesterolemic apoE(-/-) mouse: implications for a "multihit" hypothesis of fatty liver disease.	HIF1A NOS2	1.57e-05	3	80	2	19280709
Pubmed	Clinicopathological implications of the expression of hypoxia-related proteins in gastric cancer.	HIF1A NOS2	1.57e-05	3	80	2	23935399
Pubmed	Splicing switch of an epigenetic regulator by RNA helicases promotes tumor-cell invasiveness.	DDX17 DDX5	1.57e-05	3	80	2	23022728
Pubmed	RNA helicases DDX5 and DDX17 dynamically orchestrate transcription, miRNA, and splicing programs in cell differentiation.	DDX17 DDX5	1.57e-05	3	80	2	24910439
Pubmed	Changes in gene expression patterns in postmortem human myocardial infarction.	HIF1A NOS2	1.57e-05	3	80	2	32399898
Pubmed	[Expression of hypoxia-inducible factor-1alpha in nasal polyps and its correlation with vascular endothelial growth factor and inducible nitric oxide synthase].	HIF1A NOS2	1.57e-05	3	80	2	16229182
Pubmed	Hypoxic tumor microenvironment activates GLI2 via HIF-1α and TGF-β2 to promote chemoresistance in colorectal cancer.	HIF1A GLI2	1.57e-05	3	80	2	29891662
Pubmed	Modulation of NF-κB and hypoxia-inducible factor--1 by S-nitrosoglutathione does not alter allergic airway inflammation in mice.	HIF1A NOS2	1.57e-05	3	80	2	20693401
Pubmed	Hedgehog signalling controls sinoatrial node development and atrioventricular cushion formation.	GLI2 MEIS1 RYR2	2.29e-05	24	80	3	34062094
Pubmed	Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation.	VPS13C ZNFX1 CGNL1 STIL REV3L	2.76e-05	152	80	5	34299191
Pubmed	The DEAD box protein p68: a novel transcriptional coactivator of the p53 tumour suppressor.	DDX17 DDX5	3.13e-05	4	80	2	15660129
Pubmed	Integrative analysis of large-scale loss-of-function screens identifies robust cancer-associated genetic interactions.	DDX17 DDX5	3.13e-05	4	80	2	32463358
Pubmed	Relation of hypoxia-inducible factor-1alpha to vascular endothelial growth factor and vasoactive factors during healing of gastric ulcers.	HIF1A NOS2	3.13e-05	4	80	2	15838334
Pubmed	Identification of cytoplasmic proteins interacting with unliganded estrogen receptor α and β in human breast cancer cells.	DDX17 DDX5	3.13e-05	4	80	2	25604459
Pubmed	Hypoxia-inducible factor-1α, vascular endothelial growth factor, inducible nitric oxide synthase, and endothelin-1 expression correlates with angiogenesis in congenital heart disease.	HIF1A NOS2	3.13e-05	4	80	2	27450023
Pubmed	Three-amino-acid-loop-extension homeodomain factor Meis3 regulates cell survival via PDK1.	MEIS3 MEIS1	3.13e-05	4	80	2	21059917
Pubmed	RNA binding protein DDX5 restricts RORγt+ Treg suppressor function to promote intestine inflammation.	HIF1A DDX5	3.13e-05	4	80	2	36724232
Pubmed	Identification of a conserved family of Meis1-related homeobox genes.	MEIS3 MEIS1	3.13e-05	4	80	2	9049632
Pubmed	Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.	ARAP3 DOCK11 MYO9A PDZD11 MPDZ ARHGAP30 ARHGEF4 PREX1 SDHA DCAF7	4.76e-05	916	80	10	32203420
Pubmed	Molecular profiling of the vestibular lamina highlights a key role for Hedgehog signalling.	BOC SNED1 MEIS1	5.03e-05	31	80	3	36971701
Pubmed	Ultrasound induces hypoxia-inducible factor-1 activation and inducible nitric-oxide synthase expression through the integrin/integrin-linked kinase/Akt/mammalian target of rapamycin pathway in osteoblasts.	HIF1A NOS2	5.20e-05	5	80	2	17588951
Pubmed	EGFR-HIF1α signaling positively regulates the differentiation of IL-9 producing T helper cells.	HIF1A NOS2	5.20e-05	5	80	2	34075041
Pubmed	Identification of RNA helicases in human immunodeficiency virus 1 (HIV-1) replication - a targeted small interfering RNA library screen using pseudotyped and WT HIV-1.	DDX17 DDX5	5.20e-05	5	80	2	25701821
Pubmed	Transcription-dependent nucleolar cap localization and possible nuclear function of DExH RNA helicase RHAU.	DDX17 DDX5	5.20e-05	5	80	2	18279852
Pubmed	Priming of hypoxia-inducible factor by neuronal nitric oxide synthase is essential for adaptive responses to severe anemia.	HIF1A NOS2	5.20e-05	5	80	2	21976486
Pubmed	Inflammasome sensor Nlrp1b-dependent resistance to anthrax is mediated by caspase-1, IL-1 signaling and neutrophil recruitment.	NLRP1 NOS2	5.20e-05	5	80	2	21170303
Pubmed	Transcriptional Repression of Aerobic Glycolysis by OVOL2 in Breast Cancer.	DDX17 PDZD11 DDX5 DCAF7	7.05e-05	95	80	4	35896951
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	IGF2BP2 CEP89 DOCK11 PDZD11 MPDZ CSPP1 DCAF7	7.72e-05	446	80	7	24255178
Pubmed	Metabolic adaptation to glycolysis is a basic defense mechanism of macrophages for Mycobacterium tuberculosis infection.	HIF1A NOS2	7.79e-05	6	80	2	31201418
Pubmed	Characterization of TALE genes expression during the first lineage segregation in mammalian embryos.	MEIS3 MEIS1	7.79e-05	6	80	2	22987645
Pubmed	Distinct DDX DEAD-box RNA helicases cooperate to modulate the HIV-1 Rev function.	DDX17 DDX5	7.79e-05	6	80	2	23608157
Pubmed	The RNA helicases p68/p72 and the noncoding RNA SRA are coregulators of MyoD and skeletal muscle differentiation.	DDX17 DDX5	7.79e-05	6	80	2	17011493
Pubmed	Regulation of EphA8 gene expression by TALE homeobox transcription factors during development of the mesencephalon.	MEIS3 MEIS1	1.09e-04	7	80	2	17178831
Pubmed	Sumoylation of p68 and p72 RNA helicases affects protein stability and transactivation potential.	DDX17 DDX5	1.09e-04	7	80	2	19995069
Pubmed	PBX, MEIS, and IGF-I are potential mediators of retinoic acid-induced proximodistal limb reduction defects.	MEIS3 MEIS1	1.09e-04	7	80	2	12397630
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	MDN1 ZNFX1 REV3L CTNND2 CSPP1 PREX1 RYR2 AKR7A2	1.11e-04	638	80	8	31182584
Pubmed	Identification of Novel Proteins Co-Purifying with Cockayne Syndrome Group B (CSB) Reveals Potential Roles for CSB in RNA Metabolism and Chromatin Dynamics.	DDX17 VPS13C DDX5	1.35e-04	43	80	3	26030138
Pubmed	Spatiotemporal expression of sonic hedgehog signalling molecules in the embryonic mesencephalic dopaminergic neurons.	BOC GLI2	1.45e-04	8	80	2	34767969
Pubmed	Pleiotropic effects of p300-mediated acetylation on p68 and p72 RNA helicase.	DDX17 DDX5	1.45e-04	8	80	2	20663877
Pubmed	Hippo signaling regulates microprocessor and links cell-density-dependent miRNA biogenesis to cancer.	DDX17 DDX5	1.86e-04	9	80	2	24581491
Pubmed	Tumor-derived exosomes drive immunosuppressive macrophages in a pre-metastatic niche through glycolytic dominant metabolic reprogramming.	HIF1A NOS2	1.86e-04	9	80	2	34559989
Pubmed	Meis homeoproteins directly regulate Pax6 during vertebrate lens morphogenesis.	MEIS3 MEIS1	1.86e-04	9	80	2	12183364
Pubmed	Epithelial junction formation requires confinement of Cdc42 activity by a novel SH3BP1 complex.	MYO9A CGNL1	1.86e-04	9	80	2	22891260
Pubmed	IRG1 and Inducible Nitric Oxide Synthase Act Redundantly with Other Interferon-Gamma-Induced Factors To Restrict Intracellular Replication of Legionella pneumophila.	HIF1A NOS2	1.86e-04	9	80	2	31719183
Pubmed	Autonomous and non-autonomous Shh signalling mediate the in vivo growth and guidance of mouse retinal ganglion cell axons.	BOC GLI2	1.86e-04	9	80	2	18832395
Pubmed	Polymorphisms in angiogenesis-related genes and prostate cancer.	HIF1A NOS2	1.86e-04	9	80	2	18398039
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	DDX17 MDN1 CGNL1 SDHA DDX5	2.11e-04	234	80	5	36243803
Pubmed	Construction of a multi-functional cDNA library specific for mouse pancreatic islets and its application to microarray.	PDZD11 TGFBRAP1 MED12L MEIS3 NPHP4 CSPP1	2.19e-04	371	80	6	15747579
Pubmed	Full activation of estrogen receptor alpha activation function-1 induces proliferation of breast cancer cells.	DDX17 DDX5	2.32e-04	10	80	2	12738788
Pubmed	Identification of a new family of Pbx-related homeobox genes.	MEIS3 MEIS1	2.32e-04	10	80	2	8950991
Pubmed	SARS-CoV-2 N Protein Antagonizes Stress Granule Assembly and IFN Production by Interacting with G3BPs to Facilitate Viral Replication.	IGF2BP2 PPAN DDX17 SDHA DDX5	2.60e-04	245	80	5	35652658
Pubmed	Rostral hindbrain patterning involves the direct activation of a Krox20 transcriptional enhancer by Hox/Pbx and Meis factors.	MEIS3 MEIS1	2.84e-04	11	80	2	18787068
Pubmed	Expanded CUG repeats Dysregulate RNA splicing by altering the stoichiometry of the muscleblind 1 complex.	DDX17 DDX5	2.84e-04	11	80	2	21900255
Pubmed	Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India.	IGF2BP2 SACS	2.84e-04	11	80	2	23300278
Pubmed	The centrosomal deubiquitylase USP21 regulates Gli1 transcriptional activity and stability.	SLF1 GLI2	2.84e-04	11	80	2	27621083
Pubmed	Podocan, a novel small leucine-rich repeat protein expressed in the sclerotic glomerular lesion of experimental HIV-associated nephropathy.	EPYC OMD	2.84e-04	11	80	2	12796502
Pubmed	Adaptive mechanisms that preserve cardiac function in mice without myoglobin.	HIF1A NOS2	3.40e-04	12	80	2	11304494
Pubmed	Transcription factors, cAMP-responsive element modulator (CREM) and Tisp40, act in concert in postmeiotic transcriptional regulation.	DDX17 DDX5	3.40e-04	12	80	2	16595651
Pubmed	A network comprising short and long noncoding RNAs and RNA helicase controls mouse retina architecture.	DDX17 DDX5	3.40e-04	12	80	2	26041499
Pubmed	Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods.	CEP89 STIL NPHP4 CSPP1	3.68e-04	146	80	4	21399614
Pubmed	The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.	ORC5 DDX17 ZBED4 INTS1 SDHA DDX5 DCAF7	3.96e-04	583	80	7	29844126
Pubmed	A CASPR1-ATP1B3 protein interaction modulates plasma membrane localization of Na+/K+-ATPase in brain microvascular endothelial cells.	DDX17 DDX5	4.01e-04	13	80	2	30792309
Pubmed	Ptch2/Gas1 and Ptch1/Boc differentially regulate Hedgehog signalling in murine primordial germ cell migration.	BOC GLI2	4.01e-04	13	80	2	32332736
Pubmed	Hypomorphic mutation of the TALE gene Prep1 (pKnox1) causes a major reduction of Pbx and Meis proteins and a pleiotropic embryonic phenotype.	MEIS3 MEIS1	4.01e-04	13	80	2	16847320
Pubmed	Nucleolar localization of DGCR8 and identification of eleven DGCR8-associated proteins.	DDX17 DDX5	4.01e-04	13	80	2	17765891
Pubmed	Pax6 is regulated by Meis and Pbx homeoproteins during pancreatic development.	MEIS3 MEIS1	4.01e-04	13	80	2	17049510
Pubmed	SHLD2/FAM35A co-operates with REV7 to coordinate DNA double-strand break repair pathway choice.	ORC5 PARP2 INTS1 REV3L	4.08e-04	150	80	4	30154076
Pubmed	Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.	DDX17 MDN1 INTS1 DDX5 DCAF7	4.20e-04	272	80	5	31010829
Pubmed	Violating the splicing rules: TG dinucleotides function as alternative 3' splice sites in U2-dependent introns.	UBE3B MPDZ NPHP4	4.21e-04	63	80	3	17672918
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	DDX17 SACS MYO9A PRICKLE2 ZNFX1 CGNL1 ARHGEF4 CTNND2 SPECC1 SDHA DDX5	4.26e-04	1431	80	11	37142655
Pubmed	Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.	VPS13C INTS1 ZNFX1 PREX1	4.39e-04	153	80	4	10718198
GeneFamily	Prickle planar cell polarity proteins\|LIM domain containing	PRICKLE3 PRICKLE2	4.85e-05	4	52	2	1184
GeneFamily	Small leucine rich repeat proteoglycans	EPYC OMD	5.26e-04	12	52	2	573
GeneFamily	TALE class homeoboxes and pseudogenes	MEIS3 MEIS1	2.52e-03	26	52	2	526
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	ARAP3 DOCK11 ARHGEF4 PREX1	2.89e-03	206	52	4	682
GeneFamily	DEAD-box helicases	DDX17 DDX5	6.49e-03	42	52	2	499
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	KPNA7 CTNND2	6.79e-03	43	52	2	409
ToppCell	Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SNED1 PRICKLE2 MEIS3 REV3L MEIS1 RYR2	9.46e-07	182	80	6	ed6ae0fd8653f213fe29906a6a4e0729a62e1b75
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SNED1 ARAP3 NLRP1 CTNND2 SPECC1 PREX1	1.33e-06	193	80	6	2e72309607902dabe3218888b22a77fe941f3570
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IGF2BP2 MPDZ CPLANE1 CSPP1 DNAH9 CFAP65	1.50e-06	197	80	6	74a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell	COVID-19-kidney-Technical/muscle_(PCT)\|kidney / Disease (COVID-19 only), tissue and cell type	ARHGEF4 CTNND2 DNAH9 CLVS1 RYR2	6.64e-06	146	80	5	c55f1bdb6ac43b4118cb27ea7c879527e1afcbab
ToppCell	droplet-Liver-Hepatocytes-24m-Myeloid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZBED4 MYO9A RNASE12 ARHGAP30 WDFY4	9.45e-06	157	80	5	ec433d2fe827abdb647be4176c231b7052482b6f
ToppCell	droplet-Liver-LIVER_NPC-30m-Myeloid-macrophage/monocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SACS HLA-DOB ARHGAP30 CTNND2 WDFY4	1.04e-05	160	80	5	8dae9b0cf90a09acb196223f45a14680102630b2
ToppCell	Control-B_intermediate-1\|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)	MDN1 SLF1 CPLANE1 WDFY4 TENT2	1.27e-05	167	80	5	948504367ecf58144d9dd74d2ec531358fc4b309
ToppCell	facs-Lung-EPCAM-24m-Myeloid-Myeloid_Dendritic_Type_1\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HLA-DOB ARHGAP30 CTNND2 WDFY4 PREX1	1.47e-05	172	80	5	cabe7b4131d72da87d3caacd8cced3a4f2cbef53
ToppCell	3'-Adult-SmallIntestine-Hematopoietic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MED12L NLRP1 ARHGAP30 WDFY4 PREX1	1.73e-05	178	80	5	da1695a936dbe3ca9ee3fb28ceb60511c47b35f8
ToppCell	356C-Fibroblasts-Fibroblast-E-\|356C / Donor, Lineage, Cell class and subclass (all cells)	SNHG28 BOC EPYC PRICKLE2 MEIS1	1.73e-05	178	80	5	a493a277d175e5e153410a745b26ebe2e0839ea0
ToppCell	356C-Fibroblasts-Fibroblast-E\|356C / Donor, Lineage, Cell class and subclass (all cells)	SNHG28 BOC EPYC PRICKLE2 MEIS1	1.73e-05	178	80	5	371218babddfd3d8a7bb82a46ce65327ee3fcf12
ToppCell	3'-Adult-SmallIntestine-Hematopoietic-B_cells\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MED12L NLRP1 ARHGAP30 WDFY4 PREX1	1.73e-05	178	80	5	580fc1d45b82010c665a313b2e7a21e0116819ef
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BOC SNED1 GLI2 MEIS1 RYR2	1.98e-05	183	80	5	7eae9b3b4d1c9b135fa7cff348393d4adec474b4
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_B-B_cell-B_c03-CD27-AIM2\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	SNED1 HLA-DOB RASL10B STIL MEIS1	2.09e-05	185	80	5	3563dd39ec58d3273f95f5bb36b9ccdc0aafb63a
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	BOC SNED1 ARAP3 NLRP1 PREX1	2.20e-05	187	80	5	35c382c0aabd46906113e5db30ea24bb8e658899
ToppCell	droplet-Limb_Muscle-nan-3m-Endothelial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CEP89 GLI2 PRICKLE2 NOS2 FBXL21P	2.31e-05	189	80	5	16a4c92dd7a0d60f3691bd3130a091a9a54730f1
ToppCell	Adult-Mesenchymal-matrix_fibroblast_2_cell-D175\|Adult / Lineage, Cell type, age group and donor	BOC SNED1 GLI2 MEIS3 MEIS1	2.37e-05	190	80	5	7dcca3469f3a3b70db0420cb94f7765f39492f06
ToppCell	LV-08._Macrophage\|World / Chamber and Cluster_Paper	DOCK11 MED12L ARHGAP30 WDFY4 PREX1	2.43e-05	191	80	5	e7a0bc46ba9ba772636a583f3387748418e18832
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SNED1 HIF1A REV3L MEIS1 RYR2	2.43e-05	191	80	5	08720998aa55131d7377c4c67c4c935865bd7d79
ToppCell	Control-Stromal_mesenchymal\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BOC SNED1 GLI2 MEIS1 RYR2	2.43e-05	191	80	5	14057205ddb9b4bbc582d1358d13cf36d979a61b
ToppCell	Children_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ARAP3 PRICKLE2 CSPP1 NOS2 MEIS1	2.43e-05	191	80	5	f229abf69a1217194f74b0502486907e07dba989
ToppCell	Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)\|World / Lineage, Cell type, age group and donor	ARAP3 PRICKLE2 NOS2 PREX1 MEIS1	2.49e-05	192	80	5	1e156bab5ecf64627890d2de9b27603d9a01f28d
ToppCell	Adult-Mesenchymal-matrix_fibroblast_2_cell\|Adult / Lineage, Cell type, age group and donor	BOC SNED1 GLI2 MEIS3 MEIS1	2.49e-05	192	80	5	d21f0f577156f17c899b08871046a26b88aea011
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	BOC SNED1 ARAP3 NLRP1 PREX1	2.49e-05	192	80	5	c0e59e642b42c055cf73d029cf54d07d9b719359
ToppCell	COVID-19-Fibroblasts-Other_FB\|COVID-19 / group, cell type (main and fine annotations)	BOC SNED1 PRICKLE2 MEIS1 RYR2	2.55e-05	193	80	5	e6b75be08e33c1de079fb5c02f0b4468128b369c
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	BOC SNED1 ARAP3 NLRP1 PREX1	2.55e-05	193	80	5	52e918884877b6659cdca0496390e440f73694a9
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	BOC SNED1 ARAP3 NLRP1 PREX1	2.62e-05	194	80	5	f76808666fb875fc787751cbfd924d9be20a8192
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SNED1 ARAP3 NLRP1 NOS2 PREX1	2.62e-05	194	80	5	e55dc30e200c9f576804acb642175eb4fa9146b5
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	BOC SNED1 ARAP3 NLRP1 PREX1	2.62e-05	194	80	5	a52c5906fce43c2f72cf7e463a3d15cde06431f6
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Immune\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK11 NLRP1 ARHGAP30 WDFY4 PREX1	2.68e-05	195	80	5	7b6c69df943842b566a596e30bb50dbe80dccc83
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	BOC SNED1 ARAP3 NLRP1 PREX1	2.75e-05	196	80	5	ab7be3858deabbd1fc44e8b9da8ff49a50bf1fb1
ToppCell	PBMC-Control-cDC_3\|Control / Compartment, Disease Groups and Clusters	DDX17 HLA-DOB ARHGAP30 WDFY4 DCAF7	2.75e-05	196	80	5	09d197b321ff9f13c0672ea059c850845b0dbbd5
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	SNED1 MEIS3 REV3L MEIS1 RYR2	2.82e-05	197	80	5	fdb92985f7df0c280b87d3e43c2394e70786a2c7
ToppCell	COVID-19-Fibroblasts-Intermediate_pathological_FB\|COVID-19 / group, cell type (main and fine annotations)	SNED1 GLI2 PRICKLE2 MEIS1 RYR2	2.82e-05	197	80	5	f1c8936986123a3151140c374fcd62d6705c530b
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	BOC SNED1 ARAP3 NLRP1 PREX1	2.82e-05	197	80	5	cd509e49bbdbf991cc5913960ff3ef275ad40628
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	BOC SNED1 ARAP3 NLRP1 PREX1	2.82e-05	197	80	5	0f467ef58f0c4dcc00b34b7b9639e03fb3ebe780
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK11 NLRP1 ARHGAP30 WDFY4 PREX1	2.82e-05	197	80	5	c9b1f2ee7eb31a66af331c5aae29e1bbb5186f5a
ToppCell	Children_(3_yrs)-Immune\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DOCK11 NLRP1 ARHGAP30 WDFY4 PREX1	2.82e-05	197	80	5	f18807124b91310fcd84238484a80ecdba684679
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic-Monocyte-derived_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NLRP1 ARHGAP30 SPECC1 WDFY4 PREX1	2.82e-05	197	80	5	826cc6baafab13e7ef5cfcf28cd79d0fbf3af38d
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	BOC SNED1 ARAP3 NLRP1 PREX1	2.82e-05	197	80	5	412cb5f37df57121ddd1492021445479c7cbccbf
ToppCell	COVID-19-Fibroblasts\|COVID-19 / group, cell type (main and fine annotations)	SNED1 GLI2 PRICKLE2 MEIS1 RYR2	2.82e-05	197	80	5	fb847f2277609c31fffcdf49517243ce0684facf
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK11 NLRP1 ARHGAP30 WDFY4 PREX1	2.82e-05	197	80	5	61ef3f417767c3f5296a26399da63e3e4f58faf8
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	BOC SNED1 ARAP3 NLRP1 PREX1	2.89e-05	198	80	5	07701c73137947ed4a27e225975329235bbb8734
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	BOC SNED1 ARAP3 NLRP1 PREX1	2.89e-05	198	80	5	31ba87552be97c9b78c9e82f98e96699ccb19824
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	BOC SNED1 ARAP3 NLRP1 PREX1	2.89e-05	198	80	5	1378c6d4ceb84b42fdd6556be3296df7a8059e6e
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	BOC SNED1 ARAP3 NLRP1 PREX1	2.89e-05	198	80	5	451003a21162eeae90739fdb502bb50b362d80c8
ToppCell	Immune\|World / Lineage, Cell type, age group and donor	DOCK11 NLRP1 ARHGAP30 WDFY4 PREX1	2.89e-05	198	80	5	65681b54d13c6997bd90a1c2a12314a80e964fe3
ToppCell	Fetal_29-31_weeks-Immune\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	DOCK11 NLRP1 ARHGAP30 WDFY4 PREX1	2.89e-05	198	80	5	5dff131356b8c22743bd27b2b21f86ee6e4a0a0d
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	BOC SNED1 ARAP3 NLRP1 PREX1	2.89e-05	198	80	5	440af8f90c7afa1c07000806bcf9110b70f489fb
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	BOC SNED1 ARAP3 NLRP1 PREX1	2.89e-05	198	80	5	fa84bf8533d1b91d2c2bcf06b710670605072b89
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	BOC SNED1 ARAP3 NLRP1 PREX1	2.89e-05	198	80	5	0a172c6d997c7cfbad34b56e80121bd104dee67d
ToppCell	Fetal_29-31_weeks-Mesenchymal\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	BOC SNED1 GLI2 MEIS1 RYR2	2.89e-05	198	80	5	21cf4d81386761d09d0f6829c01c198e5524176d
ToppCell	Fetal_29-31_weeks\|World / Lineage, Cell type, age group and donor	IGF2BP2 GLI2 MPDZ MEIS1 RYR2	2.96e-05	199	80	5	5b9d355795dd03a22f0961dfd143425c367a4654
ToppCell	Mesenchymal\|World / Lineage, Cell type, age group and donor	BOC SNED1 GLI2 MEIS1 RYR2	2.96e-05	199	80	5	4bac110c2b3609f6ee5d0e3275da0824a6240270
ToppCell	Parenchymal-NucSeq-Endothelial-Endothelia_vascular-VE_alveolar_capillary_Car4_aerocyte\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ARAP3 PRICKLE2 NOS2 PREX1 MEIS1	2.96e-05	199	80	5	dc88ce36cc066eb6c28cfd5b9b60fe07f8cc7b53
ToppCell	10x3'2.3-week_17-19-Mesenchymal_fibro-stroma\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	BOC SNED1 GLI2 PRICKLE2 CGNL1	3.03e-05	200	80	5	747c61d4e0b746278ae1f45ca4cd556c6961c76a
ToppCell	10x3'2.3-week_17-19-Mesenchymal_fibro\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	BOC SNED1 GLI2 PRICKLE2 CGNL1	3.03e-05	200	80	5	de1d193f773f4e2927baa6fc38d29754b015c6e6
ToppCell	356C-Fibroblasts-Fibroblast-E\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	SNHG28 EPYC PRICKLE2 PREX1	1.06e-04	136	80	4	edfd453c9a650d69d05a5a3ab15f7df56349fa86
ToppCell	356C-Fibroblasts-Fibroblast-E-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	SNHG28 EPYC PRICKLE2 PREX1	1.06e-04	136	80	4	03e4e2353c23ceffde35b2d0aadd15299e3db09f
ToppCell	droplet-Heart-nan-3m-Hematologic-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HLA-DOB MED12L SPECC1 WDFY4	1.18e-04	140	80	4	ab90f6f30d89761687f8836e3d327d143ce49ed4
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c10-MKI67-GZMK\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CEP89 MEIS3 NPHP4 DNAH9	1.58e-04	151	80	4	c1461d0dd622a081187eba77f454d2663df2732e
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_B-Plasma_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HLA-DOB MEI1 WDFY4 CLVS1	1.66e-04	153	80	4	3724dd498b982be693ddff9cea7671863acf3ff8
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_B-Plasma_Cell-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HLA-DOB MEI1 WDFY4 CLVS1	1.66e-04	153	80	4	d810fc5aff28449ce79b4148558b260878a2c696
ToppCell	droplet-Liver-LIVER_NPC-30m-Myeloid-myeloid_leukocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HLA-DOB ARHGAP30 CTNND2 WDFY4	1.88e-04	158	80	4	90ca742739a208d457db087655ba3d1c18a9da57
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	BOC SNED1 NLRP1 PREX1	1.93e-04	159	80	4	d3f81ba22160568ccaa6d2b04ebfd30630f9a6db
ToppCell	COVID-19-kidney-Technical/muscle_(Imm)\|kidney / Disease (COVID-19 only), tissue and cell type	ARHGEF4 CTNND2 DNAH9 RYR2	2.12e-04	163	80	4	19c28ce16a588a7f4a035c32726f6ccd67702b5b
ToppCell	10x5'-blood-Lymphocytic_B-ABC_aged-B_memory\|blood / Manually curated celltypes from each tissue	BOC HLA-DOB PRICKLE2 WDFY4	2.17e-04	164	80	4	0424b23fc540580e7c15c50a7a03dff7c25014fa
ToppCell	droplet-Lung-nan-3m-Myeloid-myeloid_dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MDN1 HLA-DOB CTNND2 WDFY4	2.17e-04	164	80	4	a67dd181eba275c191f4d0cab13df30eaa3ad913
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-Classical_Dendritic_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HLA-DOB STIL SPECC1 WDFY4	2.17e-04	164	80	4	43045879505774ac0d9b7f760557955564f06d00
ToppCell	facs-Aorta-Heart-24m-Endothelial-coronary_vascular_endothelial_cell\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARAP3 PRICKLE3 OAZ3 NOS2	2.17e-04	164	80	4	5ee3729fab794d7acb172d14ec5d91aa1a61cd61
ToppCell	Adult-Immune-dendritic_cell\|Adult / Lineage, Cell type, age group and donor	HLA-DOB MED12L SPECC1 WDFY4	2.22e-04	165	80	4	073f52698dac1fe4edd7410865f81b30e1c7196a
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling-Cycling_Connecting_Tubule_Cell_S-high\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MED12L DCLRE1A STIL OMD	2.32e-04	167	80	4	108ae6221c6edc63c0ec42c42471b3a15a594043
ToppCell	facs-Kidney-nan-24m-Lymphocytic-B_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KPNA7 HLA-DOB ARHGAP30 WDFY4	2.32e-04	167	80	4	3c4183a8225bae37b9f5341ebd1b95409ced2022
ToppCell	facs-Kidney-nan-24m-Lymphocytic-B_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KPNA7 HLA-DOB ARHGAP30 WDFY4	2.32e-04	167	80	4	28e9670586ff551b700c794313d27eedbfa1286b
ToppCell	3'_v3-lymph-node_spleen-Hematopoietic_progenitors-Progenitor\|lymph-node_spleen / Manually curated celltypes from each tissue	IGF2BP2 MED12L MPDZ MEIS1	2.32e-04	167	80	4	cb396f3edb9e8fdc316091e8e193dbba50e0be0c
ToppCell	PND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CEP89 HLA-DOB ARHGAP30 WDFY4	2.38e-04	168	80	4	943687a33fffd7e19d906b9dd385a126bcea109a
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SNED1 ARAP3 NOS2 PREX1	2.43e-04	169	80	4	987ff79ad563825dd9877ea8ccb536758f8c6700
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IGF2BP2 MPDZ CPLANE1 CFAP65	2.54e-04	171	80	4	1854a777d9eb9d3fc3ed3632332a6f89ce8131da
ToppCell	Influenza_Severe-B_intermediate\|World / Disease group and Cell class	BOC HLA-DOB MED12L WDFY4	2.54e-04	171	80	4	4d33e1dc1efc423dbdd5f4cca6d6440a68add8d0
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_B\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HLA-DOB ARHGAP30 MEI1 WDFY4	2.66e-04	173	80	4	62ba49c1c16760a8c6cde0cc44e068f94386946a
ToppCell	Leuk-UTI-Myeloid-cDC1\|Leuk-UTI / Disease, Lineage and Cell Type	HLA-DOB OMD OAZ3 WDFY4	2.66e-04	173	80	4	226bb8d881f32d65c60f5e4c034c6d465f8e7ba5
ToppCell	facs-Aorta-Heart-3m-Myeloid\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HLA-DOB ARHGAP30 SPECC1 WDFY4	2.66e-04	173	80	4	513b4d31bcfb269556c6b4cc389865fb12e52c4f
ToppCell	3'_v3-lymph-node_spleen-Hematopoietic_progenitors\|lymph-node_spleen / Manually curated celltypes from each tissue	IGF2BP2 MED12L MPDZ MEIS1	2.72e-04	174	80	4	6d9bdf4d28ff8ebb66ffd1ccdd6a4fe9440a83f3
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid-Myeloid_Dendritic_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MDN1 MYO9A CTNND2 AKR7A2	2.78e-04	175	80	4	bb058e714d21a0ec8532eaf3c7dd2faf78016bc0
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Hematopoietic-T_cells-ILCP\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TGFBRAP1 ARHGAP30 MEI1 PREX1	2.78e-04	175	80	4	f2c3e0f728a43d6988e793c8a50c964f7447db82
ToppCell	droplet-Lung-3m-Hematologic-myeloid-myeloid_dendritic_cell-dendritic_type_2\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HLA-DOB ARHGAP30 WDFY4 AKR7A2	2.84e-04	176	80	4	7b5e50eb144bf43ca0cf354a466eb58b976a79f1
ToppCell	droplet-Lung-3m-Hematologic-myeloid-myeloid_dendritic_cell-proliferating_dendritic\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HLA-DOB MED12L NLRP1 WDFY4	2.84e-04	176	80	4	581045e61cdcdfa85701343d1a7c0a72a36606a7
ToppCell	3'_v3-lymph-node_spleen-Hematopoietic_progenitors-HSC-MPP\|lymph-node_spleen / Manually curated celltypes from each tissue	IGF2BP2 MED12L MPDZ MEIS1	2.84e-04	176	80	4	32ed5623b8809b9f1aaf7a42dff9807d9376e9c2
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid-myeloid_dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MDN1 PRICKLE3 CTNND2 AKR7A2	2.84e-04	176	80	4	6b4afd2c9268172063fe5832896bea15e862579e
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SNED1 ARAP3 NLRP1 PREX1	2.84e-04	176	80	4	dc5a22f9d1347f157bdd93e6e5769b983deccf1a
ToppCell	facs-Lung-24m-Hematologic-myeloid-myeloid_dendritic_cell-myeloid_dendritic_type_1\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ARHGAP30 CTNND2 WDFY4 PREX1	2.84e-04	176	80	4	a85ad8b4815fde72edd5c900e882a0bc04033ea8
ToppCell	wk_08-11-Mesenchymal-Chondrocyte\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	BOC EPYC TMPRSS5 OMD	2.84e-04	176	80	4	1af28b701c4598ce761f85adbd5d79e4918d265a
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRICKLE2 REV3L MEIS1 RYR2	2.90e-04	177	80	4	9ec7f1e64312d26d434b3312b58386715dbad644
ToppCell	3'-Adult-SmallIntestine-Hematopoietic-B_cells-Memory_B\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NLRP1 ARHGAP30 WDFY4 PREX1	2.90e-04	177	80	4	0d1c39e99144fdb9c7f6f98a1ade41c73db45b65
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRICKLE2 REV3L MEIS1 RYR2	2.90e-04	177	80	4	016277dfd59b1793fddaaadc2b3f41622d76ce3a
ToppCell	PND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CEP89 HLA-DOB ARHGAP30 WDFY4	2.90e-04	177	80	4	c506b8fd9a550e6cf93b64a1f7eed2543224a140
ToppCell	droplet-Lung-21m-Epithelial-airway_epithelial-lung_ciliated_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FAM47E NPHP4 DNAH9 CFAP65	2.90e-04	177	80	4	d947ba38db1772fc5fdcdc211f7511c4aa699dee
ToppCell	PND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CEP89 HLA-DOB ARHGAP30 WDFY4	2.90e-04	177	80	4	840eaac045ada42cae0ab81177d1d0ae55a65633
ToppCell	wk_15-18-Mesenchymal-Chondrocyte-Resting_chondrocyte\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	BOC EPYC VXN TMPRSS5	2.90e-04	177	80	4	b01d7a6a78169962123ddfb0bb588f51d138ad02
ToppCell	droplet-Lung-21m-Epithelial-airway_epithelial-lung_ciliated_cell-ciliated_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FAM47E NPHP4 DNAH9 CFAP65	2.90e-04	177	80	4	d5640f0097878f0dac671e51dc51310278bb2682
Disease	Anoxic-Ischemic Encephalopathy	HIF1A NOS2	6.69e-05	5	77	2	C0752305
Disease	Hypoxic-Ischemic Encephalopathy	HIF1A NOS2	6.69e-05	5	77	2	C0752304
Disease	Anoxia-Ischemia, Cerebral	HIF1A NOS2	6.69e-05	5	77	2	C0752307
Disease	Anoxia-Ischemia, Brain	HIF1A NOS2	6.69e-05	5	77	2	C0752306
Disease	Hypoxia-Ischemia, Brain	HIF1A NOS2	6.69e-05	5	77	2	C0752308
Disease	Cerebral Hypoxia-Ischemia	HIF1A NOS2	6.69e-05	5	77	2	C0178540
Disease	Cholangitis, Sclerosing	HIF1A NOS2	1.00e-04	6	77	2	C0008313
Disease	restless legs syndrome (implicated_via_orthology)	MEIS3 MEIS1	1.86e-04	8	77	2	DOID:0050425 (implicated_via_orthology)
Disease	Primary sclerosing cholangitis	HIF1A NOS2	1.86e-04	8	77	2	C0566602
Disease	Polydactyly	GLI2 UBE3B CPLANE1 CSPP1	2.54e-04	117	77	4	C0152427
Disease	Gastrointestinal Stromal Sarcoma	BOC GLI2 SDHA	2.55e-04	47	77	3	C3179349
Disease	chronic lymphocytic leukemia	ORC5 KPNA7 HLA-DOB TMPRSS5	2.71e-04	119	77	4	EFO_0000095
Disease	abdominal obesity-metabolic syndrome (implicated_via_orthology)	DDX17 DDX5	2.98e-04	10	77	2	DOID:0060611 (implicated_via_orthology)
Disease	Gastrointestinal Stromal Tumors	BOC GLI2 SDHA	3.07e-04	50	77	3	C0238198
Disease	response to ondansetron, QT interval	MPDZ ARHGEF4	3.64e-04	11	77	2	EFO_0004682, EFO_0020997
Disease	Malignant neoplasm of breast	BOC HIF1A ARAP3 PRICKLE3 MANEA RASL10B ARHGEF4 DNAH9 NOS2 MEIS1	4.70e-04	1074	77	10	C0006142
Disease	peak insulin response measurement	IGF2BP2 URGCP	5.15e-04	13	77	2	EFO_0008000
Disease	hepatic encephalopathy (biomarker_via_orthology)	HIF1A NOS2	6.90e-04	15	77	2	DOID:13413 (biomarker_via_orthology)
Disease	susceptibility to mononucleosis measurement	MDN1 MANEA RYR2	7.91e-04	69	77	3	EFO_0008403
Disease	epilepsy (implicated_via_orthology)	PRICKLE3 PRICKLE2 DEPDC5 NOS2	8.88e-04	163	77	4	DOID:1826 (implicated_via_orthology)
Disease	leukemia (implicated_via_orthology)	MEIS3 MEIS1	1.12e-03	19	77	2	DOID:1240 (implicated_via_orthology)
Disease	pulmonary hypertension (biomarker_via_orthology)	HIF1A NOS2 RYR2	1.21e-03	80	77	3	DOID:6432 (biomarker_via_orthology)
Disease	Joubert syndrome 1	CPLANE1 CSPP1	1.37e-03	21	77	2	C4551568
Disease	psoriatic arthritis	HLA-DOB REV3L NOS2	1.55e-03	87	77	3	EFO_0003778
Disease	AIDS	TGFBRAP1 MPDZ	2.10e-03	26	77	2	EFO_0000765
Disease	glucose tolerance test	IGF2BP2 VPS13C	2.26e-03	27	77	2	EFO_0004307
Disease	amyloid-beta measurement	BOC CGNL1 ARHGEF4 CTNND2 TENT2	2.38e-03	355	77	5	EFO_0005194
Disease	cerebral white matter volume change measurement, age at assessment	HLA-DOB PRICKLE2	2.43e-03	28	77	2	EFO_0008007, EFO_0021499
Disease	Seizures	MED12L MPDZ NOS2 TBC1D20	2.57e-03	218	77	4	C0036572

Protein segments in the cluster

Peptide	Gene	Start	Entry
QCPQVDLFYLHAPDH	AKR7A2	131	O43488
PDISHQPAAALLHIY	nan	121	Q9N2J8
PHPQYPDHSQLLQAL	ARAP3	606	Q8WWN8
VDPHLQFYHPQRLSL	B4GALNT3	76	Q6L9W6
PLQLAELLKYTHPQH	ARHGEF4	431	Q9NR80
LHTYLPAHIPYQELN	SPECC1	1001	Q5M775
YPESFSPAIQLHLVH	TENT2	356	Q6PIY7
LQDRDHLSYIPPEQH	CBLL2	171	Q8N7E2
RALQSPEHHIDPIYE	CTNND2	411	Q9UQB3
HSTIIYEDPQHHPLL	DCAF7	211	P61962
LQSPEHPLDQHYRNL	PARP2	351	Q9UGN5
LFQHLTHPYPSEEQK	MEIS1	291	O00470
PHHYRLVQDSQPLDL	NOS2	706	P35228
IAHPNDEYSPLLLQV	DEPDC5	41	O75140
PCHHIQQLLAYDVLP	KPNA7	356	A9QM74
QQTLPPHEAKHYLSL	MDN1	3641	Q9NU22
DPLLHQDPVQLDFHF	OAZ3	111	Q9UMX2
LLRHLQYATHFPIPL	MED12L	701	Q86YW9
LNLCTYHHPENIQLP	INTS1	706	Q8N201
VFYELAHQLPLPHNV	HIF1A	36	Q16665
EHHIPQYSLDVPKLF	CFAP65	771	Q6ZU64
LSYLLPAIVHINHQP	DDX5	146	P17844
HLYLTDNNLDHIPLP	EPYC	241	Q99645
VHHPDYNNELTQFLP	PDZD11	31	Q5EBL8
QEHPIPLSYSFIHLC	NLRP1	611	Q9C000
YLDPPRDHHTLEIQQ	CSPP1	1031	Q1MSJ5
IQNILHIPPQYLHLV	CES5A	371	Q6NT32
LFQHLSHPYPSEEQK	MEIS3	281	Q99687
ASAPHLHDYLNPVDV	GLI2	201	P10070
HHSYPEQEIVNLFIP	IGF2BP2	421	Q9Y6M1
LVPLAYFLHPQVHDQ	NUDT7	146	P0C024
ELAEKLHLQAPQHYP	MPI	116	P34949
TRALLHQTLYHPDQP	ITFG2	421	Q969R8
LNLDELPPLNNYLHV	MANEA	91	Q5SRI9
SLAPQLYLRPHETAH	NPHP4	1046	O75161
LEGIPDLQLVYTHHP	MEI1	766	Q5TIA1
LLHQLPPHDNEVRYC	PRICKLE2	76	Q7Z3G6
QLLHQLPPHDSEAQY	PRICKLE3	131	O43900
YTLPDDSTHQLLQPH	BOC	1001	Q9BWV1
TVYPERTPLLHQHNL	HLA-DOB	126	P13765
QTICNHEHYIPLNLP	DOCK11	1071	Q5JSL3
YPRLSLLHSHLSPEN	CPLANE1	2396	Q9H799
HLLNFQRHPELLQPY	CGNL1	141	Q0VF96
LYAVPHRNQVPLLHE	CEP89	156	Q96ST8
NKLHVQEQYIHPLPL	DCLRE1A	761	Q6PJP8
LLPAIVHINHQPYLE	DDX17	226	Q92841
LILHTKLANPHYQPE	DNAH9	3551	Q9NYC9
TLEHLHVDYPQNDVP	RNASE12	26	Q5GAN4
HDLDLQPYLHNVPKT	SACS	1296	Q9NZJ4
LQDLIGYFHPPDEHL	RYR2	456	Q92736
HISDPYNVNLPLHIT	ARHGAP30	411	Q7Z6I6
LHLEHNNLEEFPFPL	OMD	146	Q99983
PHHVVLQIFQYLPLL	FBXL21P	46	Q9UKT6
HVHDLQILDFPPISA	RASL10B	51	Q96S79
HLTPHPLALYLNLEE	FAM47E	121	Q6ZV65
YLVPDTQALCHHLPV	SMG5	856	Q9UPR3
KDHVYLQLHHLPPEQ	SDHA	361	P31040
NLQKILSHDHPPEYS	ORC5	186	O43913
LSLSILHPAYAPIEH	PNPLA5	81	Q7Z6Z6
LHPAYAPIEHVKQQL	PNPLA5	86	Q7Z6Z6
ALEYCLHPEPQSQHE	PREX1	116	Q8TCU6
ELGPQHSEPAHLYII	SNED1	1181	Q8TER0
NTLNPLVLPEYLIHA	CNIH1	46	O95406
NSLHQLIHPEFLPSE	CLVS1	256	Q8IUQ0
FALPLVLPDSENHYH	URGCP	211	Q8TCY9
INHLEHLKPLQPQLY	STIL	456	Q15468
HPPLHEYADLNQLTQ	TGFBRAP1	401	Q8WUH2
NIEYAHVPHLSPAVI	MPDZ	71	O75970
QPHEAHIPYLLQLFI	REV3L	151	O60673
HEQQFAHPPLLVLNS	PPAN	131	Q9NQ55
LHYLPHDPLHQELSF	RNF44	251	Q7L0R7
LPRLYHEDHPQLSEE	WDFY4	841	Q6ZS81
VERIIPHPLYSAQNH	TMPRSS5	291	Q9H3S3
YHPDIQLLHPINLEF	VPS13C	1311	Q709C8
PHLVHKLPLSYLQTQ	SNHG28	131	P0DPA3
LQAHYIPPVCVLHAL	SLF1	436	Q9BQI6
RLLTPHIYQDLENHP	ZNFX1	1081	Q9P2E3
RAQLILQYIPHVIPH	UBE3B	636	Q7Z3V4
ESDLYTHQPLELLPH	VXN	46	Q8TAG6
HHLLSQIPQDLPYET	TBC1D20	276	Q96BZ9
EYALPQHHLIQDVPS	ZBED4	876	O75132
VIPAHQFPDELAAYH	MYO9A	1791	B2RTY4