Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiondiacylglycerol binding

UNC13B UNC13A

3.13e-0416332GO:0019992
GeneOntologyMolecularFunctionsyntaxin-1 binding

UNC13B UNC13A

7.15e-0424332GO:0017075
GeneOntologyMolecularFunctionspectrin binding

ANK2 UNC13A

1.44e-0334332GO:0030507
GeneOntologyBiologicalProcessdense core granule docking

UNC13B UNC13A

2.48e-062332GO:0061790
GeneOntologyBiologicalProcessRNA splicing

RBM5 RBM15 DDX17 CLK2 LUC7L2 RBM10 ZC3H13

1.20e-05502337GO:0008380
GeneOntologyBiologicalProcessdense core granule priming

UNC13B UNC13A

1.49e-054332GO:0061789
GeneOntologyBiologicalProcessregulation of RNA splicing

RBM5 RBM15 DDX17 CLK2 RBM10

1.83e-05207335GO:0043484
GeneOntologyBiologicalProcessmRNA processing

RBM5 RBM15 DDX17 LEO1 LUC7L2 RBM10 ZC3H13

2.18e-05551337GO:0006397
GeneOntologyBiologicalProcessregulation of mRNA splicing, via spliceosome

RBM5 RBM15 DDX17 RBM10

5.19e-05129334GO:0048024
GeneOntologyBiologicalProcesspresynaptic dense core vesicle exocytosis

UNC13B UNC13A

1.11e-0410332GO:0099525
GeneOntologyBiologicalProcessregulation of mRNA processing

RBM5 RBM15 DDX17 RBM10

1.14e-04158334GO:0050684
GeneOntologyBiologicalProcessregulation of alternative mRNA splicing, via spliceosome

RBM5 RBM15 DDX17

1.14e-0459333GO:0000381
GeneOntologyBiologicalProcessneuronal dense core vesicle exocytosis

UNC13B UNC13A

1.62e-0412332GO:0099011
GeneOntologyBiologicalProcessregulation of ribonucleoprotein complex localization

SETD2 RBM10

1.91e-0413332GO:2000197
GeneOntologyBiologicalProcessregulation of synaptic vesicle priming

UNC13B UNC13A

2.23e-0414332GO:0010807
GeneOntologyBiologicalProcessribonucleoprotein complex localization

SETD2 RBM10

2.23e-0414332GO:0071166
GeneOntologyBiologicalProcessmRNA splicing, via spliceosome

RBM5 RBM15 DDX17 LUC7L2 RBM10

2.44e-04358335GO:0000398
GeneOntologyBiologicalProcessRNA splicing, via transesterification reactions with bulged adenosine as nucleophile

RBM5 RBM15 DDX17 LUC7L2 RBM10

2.44e-04358335GO:0000377
GeneOntologyBiologicalProcessRNA splicing, via transesterification reactions

RBM5 RBM15 DDX17 LUC7L2 RBM10

2.57e-04362335GO:0000375
GeneOntologyBiologicalProcessdense core granule exocytosis

UNC13B UNC13A

2.57e-0415332GO:1990504
GeneOntologyBiologicalProcessalternative mRNA splicing, via spliceosome

RBM5 RBM15 DDX17

2.72e-0479333GO:0000380
GeneOntologyBiologicalProcesssynaptic vesicle docking

UNC13B UNC13A

3.33e-0417332GO:0016081
GeneOntologyBiologicalProcessmRNA metabolic process

RBM5 RBM15 DDX17 LEO1 LUC7L2 RBM10 ZC3H13

5.20e-04917337GO:0016071
GeneOntologyBiologicalProcessregulation of short-term neuronal synaptic plasticity

UNC13B UNC13A

5.62e-0422332GO:0048172
GeneOntologyBiologicalProcesscalcium ion-regulated exocytosis of neurotransmitter

UNC13B UNC13A

7.28e-0425332GO:0048791
GeneOntologyBiologicalProcessdense core granule localization

UNC13B UNC13A

9.14e-0428332GO:0032253
GeneOntologyBiologicalProcessmyelin assembly

TENM4 ANK2

9.14e-0428332GO:0032288
GeneOntologyBiologicalProcesstranscription elongation by RNA polymerase II

SETD2 LEO1 SUPT16H

1.09e-03127333GO:0006368
GeneOntologyBiologicalProcesssynaptic vesicle priming

UNC13B UNC13A

1.12e-0331332GO:0016082
GeneOntologyBiologicalProcessheart development

RBM15 SETD2 MYH10 TENM4 ANK2 RBM10

1.14e-03757336GO:0007507
GeneOntologyBiologicalProcesscardiac septum development

RBM15 MYH10 ANK2

1.27e-03134333GO:0003279
GeneOntologyBiologicalProcessinnervation

UNC13B UNC13A

1.35e-0334332GO:0060384
GeneOntologyBiologicalProcesssecretory granule localization

UNC13B UNC13A

1.35e-0334332GO:0032252
GeneOntologyBiologicalProcesscardiac muscle tissue growth

MYH10 TENM4 RBM10

1.38e-03138333GO:0055017
GeneOntologyBiologicalProcessnucleosome organization

SETD2 CHD1 SUPT16H

1.50e-03142333GO:0034728
GeneOntologyBiologicalProcessDNA-templated transcription elongation

SETD2 LEO1 SUPT16H

1.56e-03144333GO:0006354
GeneOntologyBiologicalProcessestablishment of organelle localization

UNC13B MYH10 UNC13A RBM10 MAD1L1

1.64e-03546335GO:0051656
GeneOntologyBiologicalProcessendodermal cell differentiation

SETD2 LEO1

1.68e-0338332GO:0035987
GeneOntologyBiologicalProcessheart growth

MYH10 TENM4 RBM10

1.69e-03148333GO:0060419
GeneOntologyCellularComponentnuclear speck

RBM15 DDX17 CLK2 LUC7L2 RBM10 ZC3H13

5.13e-05431336GO:0016607
GeneOntologyCellularComponentRNA N6-methyladenosine methyltransferase complex

RBM15 ZC3H13

8.64e-059332GO:0036396
GeneOntologyCellularComponentpresynaptic active zone cytoplasmic component

UNC13B UNC13A

5.99e-0423332GO:0098831
GeneOntologyCellularComponentneuromuscular junction

UNC13B MYH10 UNC13A

7.27e-04112333GO:0031594
DomainUnc-13

UNC13B UNC13A

9.07e-063332IPR027080
DomainMunc13_dom-2

UNC13B UNC13A

3.02e-055332IPR014772
DomainMembr_traf_MHD

UNC13B UNC13A

3.02e-055332PF10540
DomainDUF1041

UNC13B UNC13A

3.02e-055332SM01145
DomainMHD2

UNC13B UNC13A

3.02e-055332PS51259
DomainMunc13_subgr_dom-2

UNC13B UNC13A

3.02e-055332IPR019558
DomainDUF1041

UNC13B UNC13A

6.32e-057332PF06292
DomainMunc13_1

UNC13B UNC13A

6.32e-057332IPR014770
DomainCAPS_dom

UNC13B UNC13A

6.32e-057332IPR010439
DomainMHD1

UNC13B UNC13A

6.32e-057332PS51258
Domain-

RBM5 RBM10

1.35e-04103324.10.1060.10
DomainRRM_1

RBM5 RBM15 RBM10 EIF4B

4.75e-04208334PF00076
DomainRRM

RBM5 RBM15 RBM10 EIF4B

5.57e-04217334SM00360
DomainRRM_dom

RBM5 RBM15 RBM10 EIF4B

6.59e-04227334IPR000504
Domainzf-RanBP

RBM5 RBM10

6.84e-0422332PF00641
DomainRRM

RBM5 RBM15 RBM10 EIF4B

6.93e-04230334PS50102
DomainG_patch

RBM5 RBM10

7.48e-0423332SM00443
DomainG_patch_dom

RBM5 RBM10

7.48e-0423332IPR000467
DomainZnF_RBZ

RBM5 RBM10

7.48e-0423332SM00547
DomainG-patch

RBM5 RBM10

7.48e-0423332PF01585
DomainG_PATCH

RBM5 RBM10

7.48e-0423332PS50174
DomainZF_RANBP2_2

RBM5 RBM10

7.48e-0423332PS50199
DomainZF_RANBP2_1

RBM5 RBM10

8.15e-0424332PS01358
Domain-

RBM5 RBM15 RBM10 EIF4B

8.63e-042443343.30.70.330
DomainZnf_RanBP2

RBM5 RBM10

8.85e-0425332IPR001876
DomainNucleotide-bd_a/b_plait

RBM5 RBM15 RBM10 EIF4B

1.06e-03258334IPR012677
DomainC2

UNC13B RGS3 UNC13A

1.58e-03131333PF00168
DomainC2

UNC13B RGS3 UNC13A

1.79e-03137333SM00239
DomainC2

UNC13B RGS3 UNC13A

1.99e-03142333PS50004
Domain-

UNC13B RGS3 UNC13A

2.23e-031483332.60.40.150
DomainC2_dom

UNC13B RGS3 UNC13A

2.99e-03164333IPR000008
DomainC1_1

UNC13B UNC13A

4.55e-0357332PF00130
DomainZF_DAG_PE_1

UNC13B UNC13A

5.70e-0364332PS00479
Pubmed

MYC multimers shield stalled replication forks from RNA polymerase.

RBM5 BAZ1B RBM15 CHD1 FASN MYH10 DDX17 LUC7L2 RBM10 DNAJA2 EIF4B SUPT16H

5.36e-11989331236424410
Pubmed

Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.

RBM5 RBM15 FASN MYH10 DDX17 LUC7L2 RBM10 ZC3H13 DNAJA2 EIF4B

6.13e-11551331034728620
Pubmed

SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18.

RBM5 BAZ1B RBM15 LEO1 CLK2 RBM10 ZC3H13 SUPT16H

7.82e-1125133831076518
Pubmed

CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.

RBM5 BAZ1B RBM15 MYH10 DDX17 LEO1 LUC7L2 RBM10 ZC3H13 SUPT16H

1.52e-10605331028977666
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

SENP6 BAZ1B RBM15 SETD2 FASN LEO1 RBM10 ZC3H13 EIF4B MAD1L1

1.64e-09774331015302935
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

RBM5 RBM15 DMXL2 SETD2 MYH10 DDX17 LUC7L2 UNC13A RBM10 ZC3H13 SUPT16H

2.60e-091082331138697112
Pubmed

Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.

RBM5 BAZ1B RBM15 CHD1 FASN MYH10 DDX17 LUC7L2 RBM10 ZC3H13

3.88e-09847331035850772
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

SENP6 BAZ1B SETD2 CHD1 FASN MYH10 DDX17 ANK2 RBM10 EIF4B

9.83e-09934331033916271
Pubmed

The cellular EJC interactome reveals higher-order mRNP structure and an EJC-SR protein nexus.

FASN MYH10 DDX17 RBM10 ZC3H13 EIF4B

1.20e-0816933623084401
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

SENP6 BAZ1B RBM15 SETD2 CHD1 DDX17 RBM10 ZC3H13 EIF4B SUPT16H

1.20e-08954331036373674
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

RBM5 BAZ1B RBM15 SETD2 DDX17 LEO1 LUC7L2 RBM10 ZC3H13 DNAJA2 SUPT16H

1.65e-081294331130804502
Pubmed

A comprehensive resource of interacting protein regions for refining human transcription factor networks.

SENP6 BAZ1B ANK2 RGS3 ZC3H13 SEC62

2.48e-0819133620195357
Pubmed

Deubiquitinating enzyme PSMD14 promotes tumor metastasis through stabilizing SNAIL in human esophageal squamous cell carcinoma.

RBM5 FASN MYH10 DDX17 LUC7L2 RBM10 EIF4B

6.21e-0838333729331416
Pubmed

TNIP2 is a Hub Protein in the NF-κB Network with Both Protein and RNA Mediated Interactions.

RBM15 LSR FASN MYH10 DDX17 ZC3H13 DNAJA2 EIF4B SUPT16H

1.35e-0792233927609421
Pubmed

Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.

RBM5 RBM15 FASN DDX17 RGS3 RBM10

2.01e-0727233631010829
Pubmed

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.

BAZ1B RBM15 CHD1 FASN MYH10 DDX17 CLK2 LUC7L2 ZC3H13 SUPT16H

2.46e-071318331030463901
Pubmed

PINK1 Content in Mitochondria is Regulated by ER-Associated Degradation.

RBM15 FASN MYH10 DDX17 ZC3H13 EIF4B SUPT16H

2.74e-0747733731300519
Pubmed

Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins.

RBM5 RBM15 FASN DDX17 CLK2 LUC7L2 RBM10 EIF4B

2.94e-0772333834133714
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

BAZ1B RBM15 SETD2 CHD1 FASN LEO1 DNAJA2 MAD1L1 SUPT16H

3.02e-07101433932416067
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

UNC13B RBM5 RBM15 FASN MYH10 ANK2 LUC7L2 SEC62 PEG3 SUPT16H

3.54e-071371331036244648
Pubmed

HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.

BAZ1B RBM15 SETD2 FASN DDX17 RBM10 DNAJA2 EIF4B

4.04e-0775433835906200
Pubmed

A bead-based approach for large-scale identification of in vitro kinase substrates.

DDX17 LEO1 RBM10 ZC3H13 EIF4B

4.54e-0716333522113938
Pubmed

Functional specialization of beta-arrestin interactions revealed by proteomic analysis.

FASN MYH10 LEO1 RGS3 RBM10 EIF4B

4.92e-0731733617620599
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

RBM5 BAZ1B RBM15 CHD1 FASN MYH10 DDX17 LUC7L2 DNAJA2 SUPT16H

5.05e-071425331030948266
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

DMXL2 FASN MYH10 DDX17 TENM4 ANK2 DOCK8 UNC13A DNAJA2 EIF4B

5.24e-071431331037142655
Pubmed

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.

RBM5 RBM15 FASN DDX17 LUC7L2 ZC3H13 EIF4B SUPT16H

6.74e-0780733822681889
Pubmed

Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.

BAZ1B CHD1 MYH10 RBM10 MAD1L1 SUPT16H

7.53e-0734133632971831
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

DMXL2 MYH10 DDX17 TENM4 ANK2 UNC13A DNAJA2 EIF4B SEC62

7.97e-07113933936417873
Pubmed

Formation and Maintenance of Functional Spines in the Absence of Presynaptic Glutamate Release.

UNC13B UNC13A

8.73e-07233228426965
Pubmed

Exon sharing of a novel human zinc-finger gene, ZIM2, and paternally expressed gene 3 (PEG3).

ZIM2 PEG3

8.73e-07233210708526
Pubmed

A fluorescent nanosensor paint detects dopamine release at axonal varicosities with high spatiotemporal resolution.

UNC13B UNC13A

8.73e-07233235613050
Pubmed

Dynamic control of synaptic vesicle replenishment and short-term plasticity by Ca(2+)-calmodulin-Munc13-1 signaling.

UNC13B UNC13A

8.73e-07233223770256
Pubmed

Membrane bridging by Munc13-1 is crucial for neurotransmitter release.

UNC13B UNC13A

8.73e-07233230816091
Pubmed

Total arrest of spontaneous and evoked synaptic transmission but normal synaptogenesis in the absence of Munc13-mediated vesicle priming.

UNC13B UNC13A

8.73e-07233212070347
Pubmed

RBM10 promotes transformation-associated processes in small cell lung cancer and is directly regulated by RBM5.

RBM5 RBM10

8.73e-07233228662214
Pubmed

A common molecular basis for membrane docking and functional priming of synaptic vesicles.

UNC13B UNC13A

8.73e-07233219558619
Pubmed

Regulation of insulin exocytosis by Munc13-1.

UNC13B UNC13A

8.73e-07233212871971
Pubmed

Phorbol esters modulate spontaneous and Ca2+-evoked transmitter release via acting on both Munc13 and protein kinase C.

UNC13B UNC13A

8.73e-07233218701688
Pubmed

Formation of perineuronal nets in organotypic mouse brain slice cultures is independent of neuronal glutamatergic activity.

UNC13B UNC13A

8.73e-07233217561838
Pubmed

Munc13 genotype regulates secretory amyloid precursor protein processing via postsynaptic glutamate receptors.

UNC13B UNC13A

8.73e-07233223070049
Pubmed

Calcium-Independent Exo-endocytosis Coupling at Small Central Synapses.

UNC13B UNC13A

8.73e-07233231851910
Pubmed

Heterodimerization of Munc13 C2A domain with RIM regulates synaptic vesicle docking and priming.

UNC13B UNC13A

8.73e-07233228489077
Pubmed

Differential control of vesicle priming and short-term plasticity by Munc13 isoforms.

UNC13B UNC13A

8.73e-07233211832228
Pubmed

Munc13-1 is essential for fusion competence of glutamatergic synaptic vesicles.

UNC13B UNC13A

8.73e-07233210440375
Pubmed

Inhibition of exocytosis or endocytosis blocks activity-dependent redistribution of synapsin.

UNC13B UNC13A

8.73e-07233222066784
Pubmed

Munc13 controls the location and efficiency of dense-core vesicle release in neurons.

UNC13B UNC13A

8.73e-07233223229896
Pubmed

Ultrastructural Correlates of Presynaptic Functional Heterogeneity in Hippocampal Synapses.

UNC13B UNC13A

8.73e-07233232187536
Pubmed

Beta phorbol ester- and diacylglycerol-induced augmentation of transmitter release is mediated by Munc13s and not by PKCs.

UNC13B UNC13A

8.73e-07233211792326
Pubmed

Autoregulation of RBM10 and cross-regulation of RBM10/RBM5 via alternative splicing-coupled nonsense-mediated decay.

RBM5 RBM10

8.73e-07233228586478
Pubmed

Molecular Mechanisms of Synaptic Vesicle Priming by Munc13 and Munc18.

UNC13B UNC13A

8.73e-07233228772123
Pubmed

Munc13-1 C1 domain activation lowers the energy barrier for synaptic vesicle fusion.

UNC13B UNC13A

8.73e-07233217267576
Pubmed

Role of mammalian homologue of Caenorhabditis elegans unc-13-1 (Munc13-1) in the recruitment of newcomer insulin granules in both first and second phases of glucose-stimulated insulin secretion in mouse islets.

UNC13B UNC13A

8.73e-07233222814762
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

RBM15 FASN DDX17 DOCK8 LUC7L2 RBM10 MAD1L1

1.04e-0658233720467437
Pubmed

FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2.

BAZ1B CHD1 MYH10 DDX17 RBM10 DNAJA2 SUPT16H

1.29e-0660133733658012
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

BAZ1B RBM15 FASN MYH10 DDX17 ZC3H13 DNAJA2 EIF4B SUPT16H

1.80e-06125733936526897
Pubmed

Suppression of ACE2 SUMOylation protects against SARS-CoV-2 infection through TOLLIP-mediated selective autophagy.

BAZ1B RBM15 FASN MYH10 DDX17 RBM10 SUPT16H

1.97e-0664133736057605
Pubmed

ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.

BAZ1B RBM15 MYH10 DDX17 RBM10 DNAJA2 SUPT16H

2.39e-0666033732780723
Pubmed

Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells.

MYH10 DDX17 LEO1 LUC7L2 RBM10 DNAJA2 SUPT16H

2.51e-0666533730457570
Pubmed

Munc13- and SNAP25-dependent molecular bridges play a key role in synaptic vesicle priming.

UNC13B UNC13A

2.62e-06333237343100
Pubmed

Interaction between Munc13-1 and RIM is critical for glucagon-like peptide-1 mediated rescue of exocytotic defects in Munc13-1 deficient pancreatic beta-cells.

UNC13B UNC13A

2.62e-06333217639022
Pubmed

The Munc13 proteins differentially regulate readily releasable pool dynamics and calcium-dependent recovery at a central synapse.

UNC13B UNC13A

2.62e-06333223658173
Pubmed

Heterogeneous Presynaptic Distribution of Munc13 Isoforms at Retinal Synapses and Identification of an Unconventional Bipolar Cell Type with Dual Expression of Munc13 Isoforms: A Study Using Munc13-EXFP Knock-in Mice.

UNC13B UNC13A

2.62e-06333233105896
Pubmed

Nonconserved Ca(2+)/calmodulin binding sites in Munc13s differentially control synaptic short-term plasticity.

UNC13B UNC13A

2.62e-06333222966208
Pubmed

Co- and post-transcriptional regulation of Rbm5 and Rbm10 in mouse cells as evidenced by tissue-specific, developmental and disease-associated variation of splice variant and protein expression levels.

RBM5 RBM10

2.62e-06333226784654
Pubmed

Aberrant morphology and residual transmitter release at the Munc13-deficient mouse neuromuscular synapse.

UNC13B UNC13A

2.62e-06333215988013
Pubmed

In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators.

BAZ1B RBM15 FASN DDX17 ANK2 RBM10 DNAJA2 EIF4B

2.68e-0697133833306668
Pubmed

PTPN14 regulates Roquin2 stability by tyrosine dephosphorylation.

RBM15 DDX17 LUC7L2 RBM10 DNAJA2 EIF4B SUPT16H

2.85e-0667833730209976
Pubmed

TRIM28-mediated nucleocapsid protein SUMOylation enhances SARS-CoV-2 virulence.

BAZ1B CHD1 FASN MYH10 DDX17 SUPT16H

2.88e-0643033638172120
Pubmed

Targeted and Interactome Proteomics Revealed the Role of PHD2 in Regulating BRD4 Proline Hydroxylation.

RBM15 FASN MYH10 DDX17 RBM10 EIF4B

3.33e-0644133631239290
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

BAZ1B RBM15 LSR CHD1 FASN DDX17 RBM10 SUPT16H

3.96e-06102433824711643
Pubmed

Characterizing ZC3H18, a Multi-domain Protein at the Interface of RNA Production and Destruction Decisions.

RBM15 MYH10 DDX17 LUC7L2 RBM10 ZC3H13 SUPT16H

4.67e-0673133729298432
Pubmed

Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.

CHD1 FASN MYH10 DDX17 LEO1 LUC7L2 DNAJA2 EIF4B SUPT16H

4.74e-06141533928515276
Pubmed

Transient, phorbol ester-induced DOC2-Munc13 interactions in vivo.

UNC13B UNC13A

5.23e-06433210488064
Pubmed

Fbxo45, a novel ubiquitin ligase, regulates synaptic activity.

UNC13B UNC13A

5.23e-06433219996097
Pubmed

Munc13-1-mediated vesicle priming contributes to secretory amyloid precursor protein processing.

UNC13B UNC13A

5.23e-06433215123597
Pubmed

ELKS1 localizes the synaptic vesicle priming protein bMunc13-2 to a specific subset of active zones.

UNC13B UNC13A

5.23e-06433228264913
Pubmed

RBM5, 6, and 10 differentially regulate NUMB alternative splicing to control cancer cell proliferation.

RBM5 RBM10

5.23e-06433224332178
Pubmed

A promiscuous biotin ligase fusion protein identifies proximal and interacting proteins in mammalian cells.

SENP6 BAZ1B FASN RBM10

5.28e-0612133422412018
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

RBM5 FASN MYH10 DDX17 ANK2 LEO1 EIF4B SEC62 SUPT16H

5.53e-06144233935575683
Pubmed

mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis.

RBM5 FASN MYH10 DDX17 RBM10

5.80e-0627433534244482
Pubmed

UBE2O promotes lipid metabolic reprogramming and liver cancer progression by mediating HADHA ubiquitination.

RBM15 MYH10 DDX17 LUC7L2 RBM10 DNAJA2

6.15e-0649133636273042
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

RBM5 DMXL2 ANK2 EIF4B PEG3 SUPT16H

6.60e-0649733623414517
Pubmed

Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.

BAZ1B MYH10 DDX17 RBM10 SUPT16H

6.78e-0628333530585729
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

RBM15 FASN DDX17 LEO1 ZC3H13 MAD1L1

7.06e-0650333616964243
Pubmed

A Noncanonical Role of Fructose-1, 6-Bisphosphatase 1 Is Essential for Inhibition of Notch1 in Breast Cancer.

MYH10 DDX17 LUC7L2 RBM10 EIF4B

7.14e-0628633532041737
Pubmed

RIM, Munc13, and Rab3A interplay in acrosomal exocytosis.

UNC13B UNC13A

8.72e-06533222248876
Pubmed

An active vesicle priming machinery suppresses axon regeneration upon adult CNS injury.

UNC13B UNC13A

8.72e-06533234706221
Pubmed

Disentangling the Roles of RIM and Munc13 in Synaptic Vesicle Localization and Neurotransmission.

UNC13B UNC13A

8.72e-06533233139401
Pubmed

Fatty Acid Synthase induced S6Kinase facilitates USP11-eIF4B complex formation for sustained oncogenic translation in DLBCL.

FASN EIF4B

8.72e-06533229483509
Pubmed

PEG3 controls lipogenesis through ACLY.

FASN PEG3

8.72e-06533234048454
Pubmed

A Trio of Active Zone Proteins Comprised of RIM-BPs, RIMs, and Munc13s Governs Neurotransmitter Release.

UNC13B UNC13A

8.72e-06533232755572
Pubmed

Identification of a Munc13-sensitive step in chromaffin cell large dense-core vesicle exocytosis.

UNC13B UNC13A

8.72e-06533226575293
Pubmed

Tumor suppressor BAP1 nuclear import is governed by transportin-1.

FASN MYH10 DDX17 LUC7L2 RBM10 DNAJA2 EIF4B SUPT16H

9.21e-06114933835446349
Pubmed

Identification of Wilms' tumor 1-associating protein complex and its role in alternative splicing and the cell cycle.

RBM15 ZC3H13

1.31e-05633224100041
Pubmed

Munc13-1 and Munc18-1 together prevent NSF-dependent de-priming of synaptic vesicles.

UNC13B UNC13A

1.31e-05633228635948
Pubmed

LOXL2 Upregulates Phosphorylation of Ezrin to Promote Cytoskeletal Reorganization and Tumor Cell Invasion.

FASN MYH10 DDX17 EIF4B SUPT16H

1.36e-0532733531409639
Pubmed

Genome-wide CRISPR-Cas9 Screen Identifies Leukemia-Specific Dependence on a Pre-mRNA Metabolic Pathway Regulated by DCPS.

BAZ1B CHD1 MYH10 LUC7L2 SUPT16H

1.64e-0534033529478914
Pubmed

Aerobic glycolysis tunes YAP/TAZ transcriptional activity.

MYH10 RBM10 EIF4B SUPT16H

1.67e-0516233425796446
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

SENP6 BAZ1B RBM15 SETD2 LEO1 DNAJA2

1.71e-0558833638580884
Pubmed

LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.

FASN MYH10 DDX17 DNAJA2 SUPT16H

1.74e-0534433530333137
InteractionRAD18 interactions

RBM5 BAZ1B RBM15 CHD1 MYH10 LEO1 CLK2 RBM10 ZC3H13 SUPT16H

1.89e-094573310int:RAD18
InteractionNUP43 interactions

SENP6 RBM15 SETD2 CHD1 DDX17 LEO1 LUC7L2 ZC3H13 DNAJA2 SUPT16H

3.72e-086253310int:NUP43
InteractionDDX23 interactions

RBM5 RBM15 SETD2 CHD1 MYH10 LEO1 RBM10 ZC3H13 SUPT16H

5.31e-08480339int:DDX23
InteractionPRMT1 interactions

RBM5 RBM15 FASN MYH10 DDX17 CLK2 LUC7L2 RBM10 ZC3H13 DNAJA2 EIF4B

1.43e-079293311int:PRMT1
InteractionNAA40 interactions

SENP6 BAZ1B SETD2 CHD1 FASN MYH10 DDX17 ANK2 RBM10 EIF4B SUPT16H

2.40e-079783311int:NAA40
InteractionFGF11 interactions

SETD2 CHD1 FASN DNAJA2 EIF4B PEG3

3.02e-07170336int:FGF11
InteractionDHX8 interactions

RBM5 RBM15 SETD2 CHD1 LUC7L2 RBM10 ZC3H13

3.86e-07292337int:DHX8
InteractionDOT1L interactions

RBM5 BAZ1B RBM15 CHD1 FASN MYH10 DDX17 LUC7L2 RBM10 ZC3H13

4.01e-078073310int:DOT1L
InteractionSNRNP40 interactions

RBM5 SENP6 RBM15 SETD2 CHD1 DDX17 RBM10 ZC3H13 SUPT16H

5.82e-07637339int:SNRNP40
InteractionEED interactions

RBM5 BAZ1B RBM15 LSR FASN MYH10 DDX17 CLK2 ZC3H13 PEG3 MAD1L1 SUPT16H

1.52e-0614453312int:EED
InteractionCENPA interactions

SENP6 BAZ1B CHD1 DDX17 LEO1 ZC3H13 SUPT16H

2.13e-06377337int:CENPA
InteractionCHD3 interactions

RBM5 BAZ1B RBM15 MYH10 DDX17 LUC7L2 RBM10 ZC3H13 SUPT16H

2.43e-06757339int:CHD3
InteractionDHX40 interactions

RBM15 SETD2 CHD1 CLK2 ZC3H13 SUPT16H

2.80e-06249336int:DHX40
InteractionSMC5 interactions

SENP6 BAZ1B RBM15 SETD2 CHD1 DDX17 RBM10 ZC3H13 EIF4B SUPT16H

2.82e-0610003310int:SMC5
InteractionMECP2 interactions

RBM5 RBM15 DMXL2 SETD2 MYH10 DDX17 LUC7L2 UNC13A RBM10 ZC3H13 SUPT16H

3.61e-0612873311int:MECP2
InteractionMEN1 interactions

RBM5 BAZ1B RBM15 CHD1 MYH10 DDX17 RBM10 ZC3H13 MAD1L1 SUPT16H

3.64e-0610293310int:MEN1
InteractionUFL1 interactions

RBM15 FASN MYH10 DDX17 LUC7L2 RBM10 DNAJA2 EIF4B SEC62 SUPT16H

3.70e-0610313310int:UFL1
InteractionMAGOH interactions

FASN MYH10 DDX17 RBM10 ZC3H13 EIF4B

3.93e-06264336int:MAGOH
InteractionCBX3 interactions

SENP6 BAZ1B SETD2 CHD1 FASN ZC3H13 MAD1L1 SUPT16H

7.29e-06646338int:CBX3
InteractionZC3H18 interactions

RBM15 MYH10 DDX17 LEO1 CLK2 LUC7L2 RBM10 ZC3H13 SUPT16H

8.07e-06877339int:ZC3H18
InteractionH3C1 interactions

SENP6 BAZ1B SETD2 CHD1 MYH10 ANK2 LEO1 LUC7L2 SUPT16H

1.00e-05901339int:H3C1
InteractionSNRPA interactions

RBM15 SETD2 DDX17 LEO1 CLK2 RBM10 SUPT16H

1.07e-05482337int:SNRPA
InteractionSSRP1 interactions

RBM15 SETD2 CHD1 DDX17 LEO1 RBM10 ZC3H13 SUPT16H

1.12e-05685338int:SSRP1
InteractionEIF4A3 interactions

FASN MYH10 DDX17 ANKRD55 RBM10 ZC3H13 EIF4B

1.34e-05499337int:EIF4A3
InteractionCHD4 interactions

RBM5 BAZ1B RBM15 MYH10 DDX17 LEO1 LUC7L2 RBM10 SUPT16H

1.38e-05938339int:CHD4
InteractionMBD6 interactions

FASN DDX17 RBM10 DNAJA2

1.44e-0591334int:MBD6
InteractionTNIP2 interactions

RBM15 LSR FASN MYH10 DDX17 ZC3H13 DNAJA2 EIF4B SUPT16H

1.56e-05952339int:TNIP2
InteractionCSNK2A1 interactions

FASN DDX17 LEO1 CLK2 LUC7L2 RBM10 ZC3H13 EIF4B SUPT16H

1.61e-05956339int:CSNK2A1
InteractionPRC1 interactions

BAZ1B RBM15 CHD1 FASN MYH10 DDX17 UNC13A RBM10 SUPT16H

1.85e-05973339int:PRC1
InteractionCPSF6 interactions

RBM15 SETD2 DDX17 LEO1 CLK2 LUC7L2 RBM10

1.88e-05526337int:CPSF6
InteractionYWHAG interactions

RBM15 LSR MYH10 DDX17 ANKRD55 CLK2 LUC7L2 ZC3H13 EIF4B MAD1L1

1.99e-0512483310int:YWHAG
InteractionSNRNP70 interactions

RBM15 MYH10 DDX17 DOCK8 CLK2 LUC7L2 RBM10 ZC3H13 DNAJA2

2.03e-05984339int:SNRNP70
InteractionCHST5 interactions

LSR ANK2 SEC62

2.31e-0534333int:CHST5
InteractionSNAI1 interactions

RBM5 FASN MYH10 DDX17 LUC7L2 RBM10 EIF4B

2.39e-05546337int:SNAI1
InteractionPTK6 interactions

CHD1 DDX17 ANKRD55 DNAJA2

2.44e-05104334int:PTK6
InteractionDCAF4 interactions

SETD2 CHD1 DDX17 CLK2 DNAJA2 SUPT16H

3.02e-05378336int:DCAF4
InteractionUBE2O interactions

RBM15 MYH10 DDX17 LUC7L2 RBM10 ZC3H13 DNAJA2 SUPT16H

3.12e-05790338int:UBE2O
InteractionRBM39 interactions

SETD2 FASN DDX17 ANKRD55 CLK2 LUC7L2 RBM10 EIF4B SUPT16H

3.19e-051042339int:RBM39
InteractionSLX4 interactions

SENP6 RBM15 CHD1 FASN DDX17 RBM10 SUPT16H

3.22e-05572337int:SLX4
InteractionNLE1 interactions

SENP6 SETD2 DDX17 ZC3H13 SUPT16H

3.25e-05228335int:NLE1
InteractionCAPZB interactions

RBM5 CHD1 FASN MYH10 DDX17 LEO1 LUC7L2 DNAJA2 EIF4B

3.36e-051049339int:CAPZB
InteractionKIF20A interactions

BAZ1B CHD1 FASN MYH10 DDX17 ANK2 DNAJA2 FAM83A SUPT16H

3.44e-051052339int:KIF20A
InteractionKCNK16 interactions

LSR SEC62 SLC27A3

4.40e-0542333int:KCNK16
InteractionYAP1 interactions

BAZ1B SETD2 CHD1 FASN MYH10 DDX17 RBM10 EIF4B SUPT16H

4.71e-051095339int:YAP1
InteractionMTF1 interactions

FASN DDX17 RBM10 SUPT16H

4.71e-05123334int:MTF1
InteractionCUL7 interactions

BAZ1B RBM15 SETD2 CHD1 FASN DDX17 RBM10 SUPT16H

5.04e-05845338int:CUL7
InteractionKCTD13 interactions

DMXL2 FASN MYH10 DDX17 TENM4 ANK2 DOCK8 UNC13A DNAJA2 EIF4B

5.16e-0513943310int:KCTD13
InteractionRBM7 interactions

FASN DDX17 CLK2 RBM10

5.18e-05126334int:RBM7
InteractionNR2C2 interactions

BAZ1B RBM15 CHD1 FASN MYH10 DDX17 CLK2 LUC7L2 ZC3H13 SUPT16H

5.45e-0514033310int:NR2C2
InteractionRNF40 interactions

RBM15 FASN LEO1 ZC3H13 EIF4B

6.19e-05261335int:RNF40
InteractionATRX interactions

SENP6 SETD2 ANK2 LUC7L2 SUPT16H

6.89e-05267335int:ATRX
InteractionCEBPB interactions

BAZ1B FASN DDX17 LEO1 LUC7L2 RBM10 DNAJA2 EIF4B MAD1L1 SUPT16H

6.91e-0514433310int:CEBPB
InteractionEFTUD2 interactions

CHD1 FASN MYH10 DDX17 LEO1 ANKRD55 LUC7L2 DNAJA2 EIF4B SUPT16H

7.16e-0514493310int:EFTUD2
InteractionCIT interactions

RBM5 BAZ1B RBM15 CHD1 FASN MYH10 DDX17 RBM10 ZC3H13 SUPT16H

7.20e-0514503310int:CIT
InteractionH2BC9 interactions

RBM5 BAZ1B LSR MYH10 EIF4B SUPT16H

7.58e-05446336int:H2BC9
InteractionOBSL1 interactions

BAZ1B RBM15 CHD1 FASN DDX17 RBM10 DNAJA2 SUPT16H

7.98e-05902338int:OBSL1
InteractionTRIM33 interactions

ZIM2 FASN MYH10 DDX17 EIF4B SUPT16H

8.26e-05453336int:TRIM33
InteractionRC3H2 interactions

RBM15 DDX17 LUC7L2 RBM10 DNAJA2 EIF4B SUPT16H

8.50e-05667337int:RC3H2
InteractionCIC interactions

SETD2 DDX17 RBM10 DNAJA2 EIF4B SEC62 SUPT16H

8.99e-05673337int:CIC
InteractionPINK1 interactions

RBM15 FASN MYH10 DDX17 ZC3H13 EIF4B SUPT16H

9.50e-05679337int:PINK1
InteractionMETTL3 interactions

RBM15 FASN ZC3H13 DNAJA2 EIF4B

9.68e-05287335int:METTL3
InteractionNUPR1 interactions

BAZ1B RBM15 MYH10 DDX17 RBM10 DNAJA2 SUPT16H

9.86e-05683337int:NUPR1
InteractionCHMP4C interactions

BAZ1B CHD1 FASN MYH10 DDX17 EIF4B SUPT16H

1.02e-04687337int:CHMP4C
InteractionSF3A1 interactions

SETD2 DDX17 DOCK8 LUC7L2 RBM10 SUPT16H

1.02e-04471336int:SF3A1
InteractionTOP1 interactions

BAZ1B RBM15 SETD2 DDX17 LEO1 RBM10 SUPT16H

1.11e-04696337int:TOP1
InteractionARRB1 interactions

CHD1 FASN RGS3 RBM10 EIF4B

1.27e-04304335int:ARRB1
InteractionDDRGK1 interactions

RBM5 RBM15 FASN DDX17 LUC7L2 RBM10 DNAJA2 SEC62 SUPT16H

1.30e-041249339int:DDRGK1
InteractionISG15 interactions

CHD1 FASN MYH10 DDX17 RGS3 SUPT16H

1.33e-04494336int:ISG15
InteractionSRPK2 interactions

RBM15 SETD2 CLK2 LUC7L2 ZC3H13 EIF4B SUPT16H

1.33e-04717337int:SRPK2
InteractionNDEL1 interactions

RBM5 ANK2 LUC7L2 RBM10

1.44e-04164334int:NDEL1
InteractionDHX15 interactions

RBM5 RBM15 FASN DDX17 RBM10 SUPT16H

1.45e-04502336int:DHX15
InteractionSRSF6 interactions

RBM5 SETD2 CLK2 LUC7L2 RBM10 ZC3H13

1.47e-04503336int:SRSF6
InteractionGLDC interactions

RBM5 FASN MYH10 DDX17 RBM10

1.64e-04321335int:GLDC
InteractionTWIST1 interactions

CHD1 FASN DNAJA2 SUPT16H

1.65e-04170334int:TWIST1
InteractionDNAJC24 interactions

FASN DNAJA2

1.70e-0412332int:DNAJC24
InteractionCOP1 interactions

SENP6 FASN DDX17 LUC7L2 MAD1L1

1.76e-04326335int:COP1
InteractionBAP1 interactions

FASN MYH10 DDX17 LUC7L2 RBM10 ZC3H13 DNAJA2 EIF4B SUPT16H

1.91e-041314339int:BAP1
InteractionPOLR2A interactions

BAZ1B SETD2 DDX17 LEO1 ZC3H13 SUPT16H

2.07e-04536336int:POLR2A
InteractionSBDS interactions

ZIM2 FASN DDX17 LUC7L2

2.10e-04181334int:SBDS
InteractionATXN1 interactions

SETD2 MYH10 DDX17 LEO1 LUC7L2 RBM10 DNAJA2 SUPT16H

2.13e-041039338int:ATXN1
InteractionPRPF8 interactions

RBM5 FASN DDX17 ANKRD55 LUC7L2 DNAJA2 SUPT16H

2.17e-04776337int:PRPF8
InteractionSREK1 interactions

DDX17 LUC7L2 RBM10 SUPT16H

2.19e-04183334int:SREK1
InteractionANO7 interactions

RBM15 FASN SUPT16H

2.21e-0472333int:ANO7
InteractionFBP1 interactions

MYH10 DDX17 LUC7L2 RBM10 EIF4B

2.38e-04348335int:FBP1
InteractionCBLL1 interactions

FASN DDX17 RBM10

2.40e-0474333int:CBLL1
InteractionCOIL interactions

RBM15 CHD1 FASN LEO1 MAD1L1 SUPT16H

2.42e-04552336int:COIL
InteractionMETTL14 interactions

CHD1 MYH10 DDX17 ZC3H13 DNAJA2 EIF4B

2.57e-04558336int:METTL14
InteractionSSTR1 interactions

SLC27A3 SUPT16H

2.69e-0415332int:SSTR1
InteractionZRSR2 interactions

RBM5 CLK2 LUC7L2

2.69e-0477333int:ZRSR2
InteractionMECOM interactions

BAZ1B RBM15 FASN DDX17 SUPT16H

2.71e-04358335int:MECOM
InteractionCLK2 interactions

SETD2 CLK2 RGS3 LUC7L2

2.79e-04195334int:CLK2
InteractionDDX39B interactions

RBM15 FASN MYH10 DDX17 DNAJA2 SUPT16H

2.88e-04570336int:DDX39B
InteractionUHRF2 interactions

BAZ1B LUC7L2 PEG3 SUPT16H

3.07e-04200334int:UHRF2
InteractionLRRC31 interactions

FASN MYH10 DDX17 SUPT16H

3.38e-04205334int:LRRC31
InteractionSLFN11 interactions

SETD2 CHD1 MYH10 RBM10 EIF4B

3.40e-04376335int:SLFN11
InteractionMED1 interactions

RBM5 FASN ZC3H13 SUPT16H

3.44e-04206334int:MED1
InteractionSUMO2 interactions

SENP6 BAZ1B FASN DDX17 MAD1L1 SUPT16H

3.50e-04591336int:SUMO2
InteractionYWHAQ interactions

LSR FASN ANKRD55 CLK2 RGS3 LUC7L2 ZC3H13 EIF4B

3.50e-041118338int:YWHAQ
InteractionZFP36L2 interactions

FASN RBM10 EIF4B SUPT16H

3.77e-04211334int:ZFP36L2
InteractionCDC5L interactions

RBM5 SENP6 FASN DDX17 DOCK8 RBM10 MAD1L1

3.92e-04855337int:CDC5L
Cytoband15q21.2

DMXL2 LEO1

2.01e-042933215q21.2
Cytoband19q13.4

ZIM2 PEG3

1.49e-037933219q13.4
GeneFamilyUNC13 homologs

UNC13B UNC13A

1.10e-054252836
GeneFamilyRNA binding motif containing

RBM5 RBM15 RBM10 EIF4B

1.95e-04213254725
GeneFamilyZinc fingers RANBP2-type |RNA binding motif containing

RBM5 RBM10

3.79e-042125289
GeneFamilyG-patch domain containing|Minor histocompatibility antigens

RBM5 RBM10

4.17e-0422252579
CoexpressionWANG_TUMOR_INVASIVENESS_UP

FASN CLK2 RBM10 ZC3H13 EIF4B SEC62

7.54e-06384336M1865
CoexpressionWANG_TUMOR_INVASIVENESS_UP

FASN CLK2 RBM10 ZC3H13 EIF4B SEC62

9.78e-06402336MM1248
CoexpressionDANG_BOUND_BY_MYC

BAZ1B LSR FASN DDX17 DNAJA2 EIF4B SEC62 SUPT16H

3.95e-051061338M15774
CoexpressionGSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_TREATED_WITH_DIGOXIN_UP

BAZ1B SETD2 FASN DOCK8

7.53e-05180334M8239
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

BAZ1B DMXL2 SETD2 CHD1 DDX17 SLC27A3 MAD1L1

7.86e-05856337M4500
CoexpressionGSE24574_BCL6_LOW_TFH_VS_TCONV_CD4_TCELL_UP

RBM5 TENM4 UNC13A PEG3

1.01e-04194334M8340
CoexpressionGSE28783_ANTI_MIR33_VS_CTRL_ATHEROSCLEROSIS_MACROPHAGE_DN

UNC13B DMXL2 ZC3H13 PEG3

1.09e-04198334M8355
CoexpressionGSE17721_LPS_VS_GARDIQUIMOD_4H_BMDC_DN

CLK2 RGS3 EIF4B SUPT16H

1.11e-04199334M4049
CoexpressionGSE6674_ANTI_IGM_VS_PL2_3_STIM_BCELL_DN

SENP6 CHD1 FASN DNAJA2

1.11e-04199334M6932
CoexpressionGSE31082_DN_VS_DP_THYMOCYTE_DN

RBM5 SENP6 CHD1 SEC62

1.13e-04200334M5055
CoexpressionTABULA_MURIS_SENIS_PANCREAS_PANCREATIC_BETA_CELL_AGEING

DDX17 ANK2 LUC7L2 PEG3

1.42e-04212334MM3816
CoexpressionMENON_FETAL_KIDNEY_0_CAP_MESENCHYME_CELLS

BAZ1B ZC3H13 SUPT16H

1.98e-0490333M39250
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_LatNas_2500_K3

BAZ1B CHD1 FASN MYH10 ANK2 LEO1 CLK2 ZC3H13 MAD1L1 SUPT16H

1.35e-0512573310facebase_RNAseq_e10.5_Emin_LatNas_2500_K3
CoexpressionAtlasDevelopingGonad_P2_ovary_emap-30224_top-relative-expression-ranked_500

RBM5 DMXL2 TENM4 LUC7L2 ZC3H13 PEG3

2.29e-05379336gudmap_developingGonad_P2_ovary_500
CoexpressionAtlasDevelopingGonad_e18.5_ovary_emap-12283_top-relative-expression-ranked_500

RBM5 DMXL2 TENM4 LUC7L2 ZC3H13 PEG3

2.57e-05387336gudmap_developingGonad_e18.5_ovary_500
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_LatNas_2500

BAZ1B CHD1 FASN MYH10 ANK2 LEO1 CLK2 ZC3H13 MAD1L1 SUPT16H

4.88e-0514593310facebase_RNAseq_e10.5_Emin_LatNas_2500
CoexpressionAtlasDevelopingGonad_e12.5_epididymis_emap-29139_top-relative-expression-ranked_200

RBM5 LUC7L2 ZC3H13 PEG3

1.05e-04159334gudmap_developingGonad_e12.5_epididymis_200
CoexpressionAtlasDevelopingGonad_e14.5_ epididymis_emap-29141_top-relative-expression-ranked_200

RBM5 LUC7L2 ZC3H13 PEG3

1.26e-04167334gudmap_developingGonad_e14.5_ epididymis_200
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_2500_k-means-cluster#5

RBM5 BAZ1B DMXL2 SETD2 CHD1 CLK2 SUPT16H

2.40e-04831337Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_2500_K5
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_2500_k-means-cluster#4

SENP6 BAZ1B MYH10 DNAJA2 SEC62 MAD1L1

2.74e-04595336Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_2500_K4
CoexpressionAtlasDevelopingKidney_e15.5_anlage of loop of Henle_emap-31283_k-means-cluster#3_top-relative-expression-ranked_1000

BAZ1B CHD1 DDX17 DOCK8 EIF4B

2.77e-04379335gudmap_developingKidney_e15.5_1000_k3
CoexpressionAtlasDevelopingGonad_e14.5_ ovary_emap-6699_top-relative-expression-ranked_500

RBM5 DMXL2 LUC7L2 ZC3H13 PEG3

2.88e-04382335gudmap_developingGonad_e14.5_ ovary_500
CoexpressionAtlasDevelopingGonad_e14.5_ epididymis_emap-29141_top-relative-expression-ranked_100

RBM5 LUC7L2 PEG3

2.99e-0484333gudmap_developingGonad_e14.5_ epididymis_100
CoexpressionAtlasDevelopingGonad_e16.5_ovary_emap-9563_top-relative-expression-ranked_500

RBM5 DMXL2 LUC7L2 ZC3H13 PEG3

3.05e-04387335gudmap_developingGonad_e16.5_ovary_500
CoexpressionAtlasDevelopingGonad_e12.5_epididymis_emap-29139_top-relative-expression-ranked_500

RBM5 TENM4 LUC7L2 ZC3H13 PEG3

3.68e-04403335gudmap_developingGonad_e12.5_epididymis_500
CoexpressionAtlasDevelopingGonad_e12.5_ovary_emap-28876_top-relative-expression-ranked_500

RBM5 TENM4 LUC7L2 ZC3H13 PEG3

3.94e-04409335gudmap_developingGonad_e12.5_ovary_500
CoexpressionAtlasDevelopingGonad_e18.5_epididymis_emap-13166_k-means-cluster#1_top-relative-expression-ranked_200

LUC7L2 PEG3

3.94e-0419332gudmap_developingGonad_e18.5_epididymis_200_k1
CoexpressionAtlasDevelopingGonad_e14.5_ epididymis_emap-29141_top-relative-expression-ranked_500

RBM5 TENM4 LUC7L2 ZC3H13 PEG3

4.12e-04413335gudmap_developingGonad_e14.5_ epididymis_500
ToppCelldroplet-Marrow-nan-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BAZ1B SETD2 CHD1 DOCK8

1.01e-051843341154a5ad7b8512272b7476f949ddac350910bfb7
ToppCelldroplet-Heart-4Chambers-21m-Endothelial-endocardial_endothelial_cells|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UNC13B LSR RGS3 PEG3

1.24e-05194334c5e77650d7abee339ec38fa78a622bb124db3fa5
ToppCelldroplet-Heart-4Chambers-21m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UNC13B LSR RGS3 PEG3

1.27e-05195334df644b4c3ddccd34614ece5a2378000e6bc0fa10
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MYH10 TENM4 UNC13A PEG3

1.35e-051983348ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SETD2 CHD1 DDX17 DOCK8

1.40e-0520033412f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellControl-Fibroblasts-Mesothelial_FB|Control / group, cell type (main and fine annotations)

TENM4 ANK2 ANKRD55

1.47e-04139333e769beb031b262dd92c9605b07dbf3c29fb82520
ToppCellCOVID-19_Mild-Neu_0|World / 5 Neutrophil clusters in COVID-19 patients

TENM4 ANK2 UNC13A

1.50e-0414033393f024473b1bb3bf93ae776fd6a8fc5e93d013f0
ToppCellAdult-Mesenchymal-vascular_smooth_muscle_cell-D175|Adult / Lineage, Cell type, age group and donor

MYH10 TENM4 ANK2

2.52e-04167333c4e321bb87512ea839f324c92c0f1afea891483f
ToppCellfacs-Heart-RA-18m-Endothelial-endothelial_cell_of_endocardium|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UNC13B RGS3 PEG3

2.57e-0416833306dc5b2d356d3a9454b10bba6f3b9ead2a0a7d46
ToppCellfacs-Heart-RA-18m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UNC13B RGS3 PEG3

2.57e-041683331002f058a340763e3d8de0bd1f0547a903526ec6
ToppCelldroplet-Marrow-nan-24m-Lymphocytic-late_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UNC13B LSR ANKRD55

2.85e-04174333cdfc50e5383c8670ce5109736aff36406f46c03d
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Mucinous_Colon_Adenocarcinoma-10|TCGA-Colorectal / Sample_Type by Project: Shred V9

MYH10 TENM4 DOCK8

3.09e-04179333cc079ba015326dccde955c5eafa3e4a2e40de192
ToppCell368C-Lymphocytic-CD4_T-cell-Treg_cell_3|368C / Donor, Lineage, Cell class and subclass (all cells)

SENP6 BAZ1B SETD2

3.20e-04181333b193f3606554adc55c5906219d114288bb1f978a
ToppCellwk_20-22-Mesenchymal-Chondrocyte-Resting_chondrocyte|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

ZIM2 TENM4 PEG3

3.25e-0418233303a5a02acd48f0eb210485348bfe0cd21f486215
ToppCelldroplet-Heart-4Chambers-18m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UNC13B LSR RGS3

3.30e-041833336c4a09c02e30e1f24dde39f8cb8c5b453826ee2e
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYH10 TENM4 PEG3

3.41e-041853333b2dfc8f4c87be516265dbecfc251276034d0efd
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYH10 TENM4 PEG3

3.41e-041853336712512100ccef456d2e2bd201d0987986c92ac9
ToppCellPND07-28-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_C|PND07-28-samps / Age Group, Lineage, Cell class and subclass

MYH10 TENM4 ANK2

3.41e-04185333427176ad9ab8d9511200fb0a132cfd1e835fe35c
ToppCellfacs-Heart-LA-24m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UNC13B LSR RGS3

3.52e-041873337b13c3b67d66f3afb410141d5471c9e78a4d8623
ToppCellfacs-Heart-LA-24m-Endothelial-endothelial_cell_of_endocardium|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UNC13B LSR RGS3

3.52e-04187333d9943e65eedab73d141eae524e2411653a751705
ToppCellfacs-Heart-RA-3m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UNC13B RGS3 PEG3

3.57e-041883334ddb11a90bf3baa7237bde304db44dfcc56aed52
ToppCellfacs-Heart-RA-3m-Endothelial-endothelial_cell_of_endocardium|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UNC13B RGS3 PEG3

3.57e-04188333e47e66906922d5c69b1aafe28face0787d3fc563
ToppCellE12.5-Mesenchymal|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MYH10 TENM4 PEG3

3.57e-041883339778dadc2bd7ded3a723e717d1c8cd3160e99c6c
ToppCelldroplet-Tongue-nan|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SENP6 CHD1 SEC62

3.57e-04188333d62cc37e86b7b186e53aeb7f421c4e5ee28f23bd
ToppCelldroplet-Heart-nan-3m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LSR RGS3 PEG3

3.63e-041893338e583ec4df0f5b79ce5211cc99ecd8616d180bde
ToppCellILEUM-inflamed-(5)_Plasma-(5)_IgA_plasma_cells|(5)_Plasma / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

DDX17 EIF4B SEC62

3.63e-04189333a0634d72bfdd5f93877724ed6480b50a3a046f71
ToppCelldroplet-Heart-nan-24m-Endothelial-endocardial_endothelial_cells|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UNC13B LSR RGS3

3.63e-041893331137583e21d874c201c20581ba1995e2bfa3de59
ToppCelldroplet-Heart-nan-24m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UNC13B LSR RGS3

3.68e-041903337068754c29f63a331e2b6c54715f3b26f37ad32b
ToppCelldroplet-Heart-4Chambers-18m-Endothelial-endocardial_endothelial_cells|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UNC13B LSR RGS3

3.68e-041903336f71a9f74af7cd9a674753cfc9833ebe5bba0fa2
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25|PBMC_fresh-frozen / Compartment, severity and other cell annotations on 10x 3' data (130k)

SETD2 CHD1 FAM83A

3.74e-041913331ecd9849d14d5ebf3daf610e83fb50820cafd3ed
ToppCell(7)_Epithelial-E_(AT2)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

UNC13B LSR FASN

3.74e-041913330fc8d109d5c50957ceef5b8b8b818b0c598b1bbe
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-lymphocytic-T_lymphocytic-T_follicular_helper_cell|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

LSR FASN MAD1L1

3.80e-041923333e2a0f332e7f9833ba88f3c809cee78b65090401
ToppCellfacs-Heart-LA-3m-Endothelial-endothelial_cell_of_endocardium|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UNC13B LSR RGS3

3.80e-0419233314a816ef116aa992f86edab411f043cf7d07fe04
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZIM2 MYH10 PEG3

3.80e-0419233320ede290e01ad574afd122d72b59dbc52c595fad
ToppCelldroplet-Pancreas-Endocrine|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDX17 LUC7L2 PEG3

3.80e-041923330dfd1e9896c34aee0f842f8de5d0e3af62a15f68
ToppCellfacs-Heart-LA-3m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UNC13B LSR RGS3

3.80e-04192333847822514d747a21d5eb40e04ba9a023fd32bd65
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANK2 LUC7L2 PEG3

3.86e-04193333fe451b3295d77b2bd1ac25cf29310c85835a45fe
ToppCelldroplet-Heart-HEART-1m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UNC13B LSR RGS3

3.86e-04193333d0a5f212f8e8a13dbbe3e41df92548ef82eef70b
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANK2 LUC7L2 PEG3

3.86e-04193333471e65f02937bc18d7c5facdacdf1df58cf0f839
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYH10 TENM4 ANK2

3.86e-04193333f25bdd10ef531b8d8441ea84573078b4b1b0f105
ToppCelldroplet-Marrow-nan-3m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BAZ1B CHD1 SUPT16H

3.92e-041943338ef0b71fef5b84cfd04973f891215333e7035d1d
ToppCellE17.5-Mesenchymal-mesenchymal_fibroblast|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MYH10 SLC27A3 PEG3

3.92e-04194333f15e81ff12525523c62d13105cf264ea72205e2e
ToppCellControl-Fibroblasts-Intermediate_pathological_FB|Control / group, cell type (main and fine annotations)

MYH10 TENM4 ANK2

3.92e-0419433303a269f75a481ea54aea8e6444605db8d6df493d
ToppCelldroplet-Limb_Muscle-MUSCLE|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SENP6 CHD1 PEG3

3.92e-04194333e3d63874111d1e8da3977329426e4dcf68d6de87
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANK2 LUC7L2 PEG3

3.92e-041943330b023de48ed8a550d169bbe954881eb04bf4f981
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte-Non-classical_monocytes-Non-classical_monocytes_L.1.2.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DMXL2 CHD1 DOCK8

3.92e-04194333dfe0ece81922bfd7c6673726d3ea2365cbdb5513
ToppCellPND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYH10 SLC27A3 PEG3

3.97e-041953333a0cad69cfc150a27a0666f612f5294c817197d7
ToppCell(1)_T_cells-(1)_T_CD4_naive|(1)_T_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)

SETD2 DDX17 ANKRD55

3.97e-04195333d3fa551bc6f5ee5890af1040415e61ecd5d46201
ToppCellPND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYH10 SLC27A3 PEG3

3.97e-041953332b8ee7990267bb52b7e6ae03f509ffebf8908122
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYH10 SLC27A3 PEG3

4.03e-04196333db64ab27374f82553ee577aec056141170f3656f
ToppCelldroplet-Heart-nan-18m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UNC13B LSR RGS3

4.03e-04196333e386526332138e636aef2542c11316347a45689c
ToppCellP07-Mesenchymal-mesenchymal_fibroblast-mesenchymal_progenitor_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MYH10 TENM4 ANK2

4.03e-0419633374093f85e095606d1c723e0d7c2d78d9cfa47c4f
ToppCellE17.5-Mesenchymal-mesenchymal_fibroblast-mesenchymal_progenitor_cell|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MYH10 TENM4 PEG3

4.03e-04196333028a06ed92f1c058dcbeacd335625bf529e87a7b
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYH10 SLC27A3 PEG3

4.03e-04196333617103f4a09e009fe96c28eb5e40505a4fd6dcf4
ToppCellP07-Mesenchymal-myocytic_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MYH10 TENM4 ANK2

4.09e-04197333378299fe2ec6ed2fc858febb78ff1ac0898e457d
ToppCellControl-Classical_Monocyte-cMono_2|Classical_Monocyte / Disease condition and Cell class

DMXL2 DOCK8 EIF4B

4.09e-04197333eb7610c9496a95a5fd866e16abcbc39b83abe617
ToppCellP07-Mesenchymal-myocytic_cell-aortic_smooth_muscle_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MYH10 TENM4 ANK2

4.09e-04197333b1135378d768fbbe62a75747d1e8653d35252187
ToppCellASK440-Epithelial-Type_2|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

UNC13B FASN SLC27A3

4.09e-0419733308d5bbeb77a4152af1c783bc958afcae24667767
ToppCell(7)_Epithelial_cells-(7)_Epithelial-E_(AT2)|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

UNC13B FASN ANK2

4.16e-04198333498f11441c0a0982738537bcfcfc2877866b7400
ToppCellControl_saline-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|Control_saline / Treatment groups by lineage, cell group, cell type

RBM15 MYH10 ANK2

4.16e-041983330c4d2c68a42f8a9e964e2dd28092fe75f5216834
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.6.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DMXL2 CHD1 DOCK8

4.22e-041993335b6feacb0ca92c3fc6b327be978320426dcf6f68
ToppCellLPS_only-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_only / Treatment groups by lineage, cell group, cell type

MYH10 ANK2 RGS3

4.22e-04199333fde2b65afde69f402f1b7b056eaa266e9fd5b227
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

FASN MYH10 ANK2

4.22e-041993338b86c69aaf60feff53aa782559cfece7342a23de
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

MYH10 DDX17 ANK2

4.28e-042003339b0916d8d07ac2bf1739f7be5296bf77ffee6094
ToppCellParenchyma_Control_(B.)-Epithelial-TX-AT2-2|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

UNC13B LSR FASN

4.28e-0420033335c05cae30cd6b323d2662f1396ddeab08bc75fc
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-AT2-2-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

UNC13B LSR FASN

4.28e-042003333c251ad03fbbdae91dfd9037880ba43adbb03807
ToppCellLung_Parenchyma-Control-Epithelial|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

UNC13B LSR FASN

4.28e-04200333c2bde99b3bc7a8740441c1a0c1394892b940b857
ToppCellBiopsy_IPF-Immune-Monocytes|Biopsy_IPF / Sample group, Lineage and Cell type

DMXL2 CHD1 DOCK8

4.28e-0420033380b2b7eecc5dce9d22f9c80562e4aea83bbf0f50
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-AT2-2|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

UNC13B LSR FASN

4.28e-04200333c905451425d1c24773bb0ca69bcf0309b277d2f1
ToppCellLPS_only-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_only / Treatment groups by lineage, cell group, cell type

MYH10 DDX17 ANK2

4.28e-04200333a7ef7022b8efcaedb7319b0b43d8c4e99d788fe2
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-AT2-1-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

UNC13B LSR FASN

4.28e-0420033365c83a3f6ee2a10bcb5b95076696232c6373a7b4
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-AT2-1|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

UNC13B LSR FASN

4.28e-0420033340e969883bc302e8fbc6b6ab9814529dc1472902
ToppCellParenchyma_Control_(B.)-Epithelial-TX|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

UNC13B LSR FASN

4.28e-042003339970e9bde6aa2ff3aef60dcb065ff15b7463e147
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW26|organoid_Tanaka_cellReport / Sample Type, Dataset, Time_group, and Cell type.

FASN ANK2 UNC13A

4.28e-042003335c7263c862093ad9dbc81d06b16b6f74e8a6b634
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-AT2-2-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

UNC13B LSR FASN

4.28e-04200333eb44d1f80ecaac3a022cd04ab16dc36151e45488
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

UNC13B LSR FASN

4.28e-042003333ff9abd5e07780a59d5571da906fa15f00a1d5c2
ToppCellParenchyma_Control_(B.)-Epithelial-TX-AT2-1|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

UNC13B LSR FASN

4.28e-04200333ad9cdc82a647d379abc713a56db0e11bb6494106
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-AT2-2|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

UNC13B LSR FASN

4.28e-04200333acc771a902cf2f060c3eb9aedb72a256f5778a6c
ToppCellParenchyma_COVID-19-Epithelial-TX-AT2-2|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

UNC13B LSR FASN

4.28e-04200333ceb613ac6cdf0e3e6bb3f04d89034e18a524cefb
ComputationalNeighborhood of HDAC1

RBM15 CLK2 RBM10 EIF4B

7.91e-05110234GNF2_HDAC1
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

SENP6 BAZ1B SETD2

1.57e-0450233GAVISH_3CA_MALIGNANT_METAPROGRAM_4_CHROMATIN
ComputationalNeighborhood of DDX5

RBM5 SETD2 CHD1

3.13e-0463233GNF2_DDX5
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A

RBM5 SENP6 LUC7L2 RBM10 PEG3

5.64e-061793355822_DN
Drug2-propylpentanoic acid; Down 200; 10000uM; MCF7; HG-U133A

SENP6 DDX17 LUC7L2 RBM10 SLC27A3

7.16e-06188335345_DN
Drug2-propylpentanoic acid; Down 200; 10000uM; HL60; HG-U133A

SENP6 DDX17 ANKRD55 LUC7L2 RBM10

7.35e-06189335410_DN
Drug2-propylpentanoic acid; Down 200; 2000uM; MCF7; HG-U133A

SENP6 DDX17 LUC7L2 RBM10 ZC3H13

9.43e-06199335346_DN
Drugsilicon cation

ZIM2 PEG3

2.03e-055332CID016019983
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A

SENP6 DDX17 TENM4 LUC7L2

1.16e-041753344072_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A

RBM5 SENP6 DDX17 LUC7L2

1.21e-041773346340_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

SENP6 BAZ1B DDX17 LUC7L2

1.21e-041773343227_DN
DrugTrichostatin A, Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A

SENP6 BAZ1B TENM4 LUC7L2

1.24e-041783344436_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A

SENP6 BAZ1B LUC7L2 PEG3

1.24e-041783345086_DN
DrugTrichostatin A, Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA

RBM5 SENP6 DDX17 LUC7L2

1.24e-041783341112_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

RBM5 SENP6 DDX17 LUC7L2

1.26e-041793345484_DN
Drugtrichostatin A, Streptomyces sp.; Down 200; 1uM; PC3; HT_HG-U133A

SENP6 SETD2 RGS3 LUC7L2

1.29e-041803346886_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HG-U133A

RBM5 SETD2 CLK2 RBM10

1.35e-041823341891_DN
DrugRifabutin [72559-06-9]; Down 200; 4.8uM; PC3; HT_HG-U133A

SENP6 BAZ1B TENM4 LUC7L2

1.38e-041833344527_DN
DrugSpiperone [749-02-0]; Down 200; 10.2uM; PC3; HT_HG-U133A

BAZ1B RGS3 SLC27A3 MAD1L1

1.47e-041863345777_DN
Drug2-propylpentanoic acid; Down 200; 1000uM; HL60; HT_HG-U133A

SENP6 DDX17 ANKRD55 LUC7L2

1.50e-041873342669_DN
Drugtrichostatin A; Down 200; 0.1uM; PC3; HG-U133A

RBM5 SENP6 LUC7L2 RBM10

1.50e-04187334448_DN
Drug6-azauracil

CHD1 LEO1 SUPT16H

1.55e-0472333CID000068037
DrugAC1L1B78

ZIM2 FASN PEG3

1.55e-0472333CID000001313
DrugPempidine tartrate [546-48-5]; Down 200; 13uM; PC3; HT_HG-U133A

RBM5 BAZ1B MYH10 DDX17

1.59e-041903344307_DN
DrugFlunisolide [3385-03-3]; Down 200; 9.2uM; PC3; HT_HG-U133A

BAZ1B SETD2 MYH10 DDX17

1.62e-041913344303_DN
Drugtrichostatin A, Streptomyces sp.; Down 200; 1uM; PC3; HT_HG-U133A

RBM5 SENP6 DDX17 LUC7L2

1.62e-041913347503_DN
DrugFenoprofen calcium salt dihydrate [53746-45-5]; Down 200; 7.2uM; PC3; HT_HG-U133A

RBM5 SENP6 SETD2 DDX17

1.66e-041923344274_DN
DrugEstropipate [7280-37-7]; Down 200; 9.2uM; MCF7; HT_HG-U133A

RBM5 BAZ1B DDX17 RGS3

1.66e-041923346808_DN
DrugN-Acetyl-DL-homocysteine Thiolactone [1195-16-0]; Down 200; 25.2uM; PC3; HT_HG-U133A

RBM5 BAZ1B MYH10 DDX17

1.66e-041923344311_DN
DrugAcacetin [480-44-4]; Down 200; 14uM; MCF7; HT_HG-U133A

RBM5 SENP6 DDX17 MAD1L1

1.66e-041923346044_DN
Drug0179445-0000 [211246-22-9]; Up 200; 10uM; PC3; HT_HG-U133A

SENP6 DDX17 ANKRD55 ZC3H13

1.69e-041933344289_UP
DrugGliclazide [21187-98-4]; Down 200; 12.4uM; PC3; HT_HG-U133A

SENP6 BAZ1B DDX17 PEG3

1.76e-041953345089_DN
Drugeuxanthone

ZIM2 PEG3

1.83e-0414332CID005281631
DrugUngerine nitrate; Down 200; 10.2uM; PC3; HT_HG-U133A

RBM5 SENP6 DDX17 MAD1L1

1.86e-041983345816_DN
Drug(-)-MK 801 hydrogen maleate [77086-19-2]; Down 200; 11.8uM; HL60; HT_HG-U133A

UNC13B SENP6 BAZ1B ANKRD55

1.86e-041983343081_DN
Drugexemestane; Down 200; 0.01uM; MCF7; HG-U133A

UNC13B RBM5 LSR DDX17

1.90e-04199334165_DN
DrugCimetidine [51481-61-9]; Up 200; 15.8uM; HL60; HG-U133A

DMXL2 SETD2 DDX17 DNAJA2

1.90e-041993341964_UP
DrugMetrizamide [31112-62-6]; Down 200; 5uM; PC3; HT_HG-U133A

SENP6 LSR SETD2 TENM4

1.94e-042003344075_DN
DiseaseNeurodevelopmental Disorders

SETD2 ANK2 DOCK8

1.54e-0493333C1535926
Diseaseepilepsy (implicated_via_orthology)

UNC13B ANK2 UNC13A

7.99e-04163333DOID:1826 (implicated_via_orthology)
DiseaseLymphoma

DOCK8 MAD1L1

9.21e-0440332C0024299
Diseasesystemic juvenile idiopathic arthritis, polyarticular juvenile idiopathic arthritis, rheumatoid factor negative, oligoarticular juvenile idiopathic arthritis

FASN ANKRD55

9.21e-0440332EFO_1001999, EFO_1002019, EFO_1002020
DiseaseColorectal Carcinoma

UNC13B CHD1 ANK2 RBM10 PEG3

1.03e-03702335C0009402
Diseasealcohol use disorder (implicated_via_orthology)

UNC13B DDX17 UNC13A

1.34e-03195333DOID:1574 (implicated_via_orthology)
Diseaselung adenocarcinoma (is_implicated_in)

SETD2 RBM10

1.38e-0349332DOID:3910 (is_implicated_in)
DiseaseIntellectual Disability

SETD2 FASN DOCK8 SUPT16H

1.50e-03447334C3714756
DiseaseAlzheimer's disease (implicated_via_orthology)

ANK2 DNAJA2

1.86e-0357332DOID:10652 (implicated_via_orthology)
Diseasemigraine disorder, type 2 diabetes mellitus

SENP6 MAD1L1

2.06e-0360332MONDO_0005148, MONDO_0005277
DiseaseCleft Palate

CHD1 RBM10

3.72e-0381332C0008925
DiseaseProstatic Neoplasms

SENP6 SETD2 CHD1 MAD1L1

4.76e-03616334C0033578
DiseaseMalignant neoplasm of prostate

SENP6 SETD2 CHD1 MAD1L1

4.76e-03616334C0376358
DiseaseAdenoid Cystic Carcinoma

ZIM2 SETD2

5.61e-03100332C0010606
Diseaseattention deficit hyperactivity disorder, unipolar depression, bipolar disorder, autism spectrum disorder, schizophrenia

TENM4 MAD1L1

5.72e-03101332EFO_0003756, EFO_0003761, EFO_0003888, MONDO_0004985, MONDO_0005090
Diseaseprostate cancer (is_implicated_in)

CHD1 MAD1L1

7.60e-03117332DOID:10283 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
DSAVDDRDSDYRSET

UNC13A

191

Q9UPW8
RSSYDDRSSDRRVYD

CLK2

56

P49760
RGRNYTEESASEDSE

BAZ1B

1241

Q9UIG0
SRDRYREEDTSEVND

ANKRD55

366

Q3KP44
DRESKSSDDVDYRGS

DMXL2

2706

Q8TDJ6
DEEDYDNDKRSSRRQ

CHD1

221

O14646
DDERRESATADAGYA

RBM10

681

P98175
ELSSSRDRYNSDNDR

RBM15

676

Q96T37
DTSDDNYGERSEAKR

RGS3

901

P49796
ADNRSLDDRSRYSAG

KCNG3

201

Q8TAE7
STEAEDRSYDKLNRD

ANK2

2751

Q01484
ERARIYSSDSDEGSE

LEO1

601

Q8WVC0
ERAASTSARNYEREV

MAD1L1

86

Q9Y6D9
RADFSDNESARLATD

FAM83A

26

Q86UY5
DSDYKRSSDDRRGDR

RBM5

36

P52756
DYDSPERERERRNSD

RBM5

56

P52756
DDRDSRAYESRSQDA

PEG3

211

Q9GZU2
QRREAYNDSSDEESS

DNAJA2

386

O60884
DTRRYRTSGSDEEQE

DOCK8

1236

Q8NF50
RRDSASYRDRSETDR

DDX17

596

Q92841
AAYRDRDSQRDLVEA

FASN

2116

P49327
DYQRELEEARASRDE

MYH10

1656

P35580
PRSRSRDDLYDQDDS

LSR

526

Q86X29
YESANGRSEDRRSSE

LUC7L2

371

Q9Y383
RYDRRDDRSWSSRDD

EIF4B

301

P23588
DDRSWSSRDDYSRDD

EIF4B

306

P23588
SSRDDYSRDDYRRDD

EIF4B

311

P23588
DRESRYEEEEEQSRS

SUPT16H

1001

Q9Y5B9
SDTDSDRREDDRSQH

SEC62

341

Q99442
FSYSEAERESNRAAR

SLC27A3

91

Q5K4L6
RDAERRYTSSSADSE

TENM4

16

Q6N022
SDDDDDNDRTNRRES

SENP6

336

Q9GZR1
DSAVDDRDSDYRSET

UNC13B

181

O14795
TDNRARESSDSEEEY

SETD2

451

Q9BYW2
DDRDSRAYESRSQDA

ZIM2

86

Q9NZV7
REEREYEQDQSSSRD

ZC3H13

431

Q5T200
YEQDQSSSRDHRDDR

ZC3H13

436

Q5T200