Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	tRNA (cytidine-3-)-methyltransferase activity	METTL2A METTL2B	6.63e-05	4	67	2	GO:0052735
GeneOntologyMolecularFunction	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	ATP6V0A1 ATP6V0A4 ATP6V0A2	6.95e-05	24	67	3	GO:0044769
GeneOntologyMolecularFunction	proton-transporting ATPase activity, rotational mechanism	ATP6V0A1 ATP6V0A4 ATP6V0A2	6.95e-05	24	67	3	GO:0046961
GeneOntologyMolecularFunction	ATPase-coupled ion transmembrane transporter activity	ATP6V0A1 ATP6V0A4 ATP6V0A2	6.95e-05	24	67	3	GO:0042625
GeneOntologyMolecularFunction	ATPase binding	ATP6V0A1 ATP6V0A4 CHRFAM7A ATP6V0A2	4.77e-04	108	67	4	GO:0051117
GeneOntologyMolecularFunction	tRNA (cytidine) methyltransferase activity	METTL2A METTL2B	4.91e-04	10	67	2	GO:0016427
GeneOntologyMolecularFunction	calcium channel activity	TRPC4AP TRPM2 CACNA1I PKD1L3	9.30e-04	129	67	4	GO:0005262
GeneOntologyCellularComponent	vacuolar proton-transporting V-type ATPase, V0 domain	ATP6V0A1 ATP6V0A4 ATP6V0A2	4.06e-06	10	69	3	GO:0000220
GeneOntologyCellularComponent	ATPase complex	MYBBP1A ATP6V0A1 KAT5 ATP6V0A4 CHD3 ATP6V0A2	4.28e-06	129	69	6	GO:1904949
GeneOntologyCellularComponent	proton-transporting V-type ATPase, V0 domain	ATP6V0A1 ATP6V0A4 ATP6V0A2	7.41e-06	12	69	3	GO:0033179
GeneOntologyCellularComponent	vacuolar proton-transporting V-type ATPase complex	ATP6V0A1 ATP6V0A4 ATP6V0A2	8.47e-05	26	69	3	GO:0016471
GeneOntologyCellularComponent	proton-transporting two-sector ATPase complex, proton-transporting domain	ATP6V0A1 ATP6V0A4 ATP6V0A2	8.47e-05	26	69	3	GO:0033177
GeneOntologyCellularComponent	proton-transporting V-type ATPase complex	ATP6V0A1 ATP6V0A4 ATP6V0A2	1.18e-04	29	69	3	GO:0033176
GeneOntologyCellularComponent	cation-transporting ATPase complex	ATP6V0A1 ATP6V0A4 ATP6V0A2	5.69e-04	49	69	3	GO:0090533
GeneOntologyCellularComponent	proton-transporting two-sector ATPase complex	ATP6V0A1 ATP6V0A4 ATP6V0A2	7.16e-04	53	69	3	GO:0016469
GeneOntologyCellularComponent	ATPase dependent transmembrane transport complex	ATP6V0A1 ATP6V0A4 ATP6V0A2	7.99e-04	55	69	3	GO:0098533
GeneOntologyCellularComponent	vacuolar membrane	ATP6V0A1 SLC38A9 ATP6V0A4 TRPM2 WDFY3 LRBA ATP6V0A2	1.40e-03	507	69	7	GO:0005774
GeneOntologyCellularComponent	endosome	ATG9B ATP6V0A1 TRIO SLC38A9 ATP6V0A4 VPS8 ANKRD50 ZDHHC1 WDFY4 CX3CR1 ATP6V0A2	1.45e-03	1167	69	11	GO:0005768
Domain	V-type_ATPase_116kDa_su_euka	ATP6V0A1 ATP6V0A4 ATP6V0A2	1.68e-07	4	66	3	IPR026028
Domain	V_ATPase_I	ATP6V0A1 ATP6V0A4 ATP6V0A2	1.68e-07	4	66	3	PF01496
Domain	V-ATPase_116kDa_su	ATP6V0A1 ATP6V0A4 ATP6V0A2	1.68e-07	4	66	3	IPR002490
Domain	PH-BEACH_dom	WDFY3 LRBA WDFY4	2.33e-06	8	66	3	IPR023362
Domain	-	WDFY3 LRBA WDFY4	2.33e-06	8	66	3	2.30.29.40
Domain	PH_BEACH	WDFY3 LRBA WDFY4	2.33e-06	8	66	3	PS51783
Domain	BEACH_dom	WDFY3 LRBA WDFY4	3.49e-06	9	66	3	IPR000409
Domain	BEACH	WDFY3 LRBA WDFY4	3.49e-06	9	66	3	PS50197
Domain	Beach	WDFY3 LRBA WDFY4	3.49e-06	9	66	3	PF02138
Domain	-	WDFY3 LRBA WDFY4	3.49e-06	9	66	3	1.10.1540.10
Domain	Beach	WDFY3 LRBA WDFY4	3.49e-06	9	66	3	SM01026
Domain	ST7	ST7 ST7L	1.23e-05	2	66	2	PF04184
Domain	ST7	ST7 ST7L	1.23e-05	2	66	2	IPR007311
Domain	ARM-type_fold	MYBBP1A TRPC4AP XPO6 HEATR5A WDFY3 LRBA TEX10 WDFY4	2.49e-05	339	66	8	IPR016024
Domain	MeTrfase	METTL2A METTL2B	7.35e-05	4	66	2	IPR026113
Domain	DUF4704	WDFY3 LRBA	1.22e-04	5	66	2	IPR031570
Domain	DUF4704	WDFY3 LRBA	1.22e-04	5	66	2	PF15787
Domain	-	XPO6 HEATR5A WDFY3 LRBA TEX10 WDFY4	1.32e-04	222	66	6	1.25.10.10
Domain	Methyltransf_12	METTL2A METTL2B	1.83e-04	6	66	2	PF08242
Domain	PH_BEACH	WDFY3 LRBA	1.83e-04	6	66	2	PF14844
Domain	Methyltransf_12	METTL2A METTL2B	1.83e-04	6	66	2	IPR013217
Domain	-	EYS PAPPA WDFY3 LRBA	3.56e-04	95	66	4	2.60.120.200
Domain	ARM-like	XPO6 HEATR5A WDFY3 LRBA TEX10 WDFY4	3.79e-04	270	66	6	IPR011989
Domain	PH_dom-like	MTMR7 TRIO RALGPS1 WDFY3 LRBA WDFY4	3.90e-03	426	66	6	IPR011993
Pathway	REACTOME_INSULIN_RECEPTOR_RECYCLING	ATP6V0A1 ATP6V0A4 ATP6V0A2	9.44e-05	30	42	3	M506
Pathway	REACTOME_INSULIN_RECEPTOR_RECYCLING	ATP6V0A1 ATP6V0A4 ATP6V0A2	1.04e-04	31	42	3	MM15467
Pathway	REACTOME_TRANSFERRIN_ENDOCYTOSIS_AND_RECYCLING	ATP6V0A1 ATP6V0A4 ATP6V0A2	1.04e-04	31	42	3	MM15639
Pathway	REACTOME_TRANSFERRIN_ENDOCYTOSIS_AND_RECYCLING	ATP6V0A1 ATP6V0A4 ATP6V0A2	1.04e-04	31	42	3	M991
Pathway	REACTOME_ROS_AND_RNS_PRODUCTION_IN_PHAGOCYTES	ATP6V0A1 ATP6V0A4 ATP6V0A2	1.64e-04	36	42	3	M26923
Pathway	REACTOME_ION_CHANNEL_TRANSPORT	TRPC4AP ATP6V0A1 ATP6V0A4 TRPM2 ATP6V0A2	1.68e-04	176	42	5	MM15718
Pathway	REACTOME_ROS_AND_RNS_PRODUCTION_IN_PHAGOCYTES	ATP6V0A1 ATP6V0A4 ATP6V0A2	1.93e-04	38	42	3	MM14519
Pathway	REACTOME_ION_CHANNEL_TRANSPORT	TRPC4AP ATP6V0A1 ATP6V0A4 TRPM2 ATP6V0A2	2.01e-04	183	42	5	M997
Pathway	KEGG_LYSOSOME	ATP6V0A1 GALNS ATP6V0A4 ATP6V0A2	4.49e-04	121	42	4	M11266
Pathway	KEGG_VIBRIO_CHOLERAE_INFECTION	ATP6V0A1 ATP6V0A4 ATP6V0A2	5.49e-04	54	42	3	M17906
Pathway	REACTOME_IRON_UPTAKE_AND_TRANSPORT	ATP6V0A1 ATP6V0A4 ATP6V0A2	6.11e-04	56	42	3	MM15638
Pathway	REACTOME_IRON_UPTAKE_AND_TRANSPORT	ATP6V0A1 ATP6V0A4 ATP6V0A2	6.77e-04	58	42	3	M962
Pathway	REACTOME_SYNTHESIS_OF_IP2_IP_AND_INS_IN_THE_CYTOSOL	MTMR7 INPP5A	7.71e-04	14	42	2	M27052
Pathway	KEGG_EPITHELIAL_CELL_SIGNALING_IN_HELICOBACTER_PYLORI_INFECTION	ATP6V0A1 ATP6V0A4 ATP6V0A2	1.08e-03	68	42	3	M16848
Pathway	REACTOME_SIGNALING_BY_INSULIN_RECEPTOR	ATP6V0A1 ATP6V0A4 ATP6V0A2	1.49e-03	76	42	3	MM15442
Pubmed	Differential localization of vacuolar H+-ATPases containing a1, a2, a3, or a4 (ATP6V0A1-4) subunit isoforms along the nephron.	ATP6V0A1 ATP6V0A4 ATP6V0A2	2.99e-08	4	69	3	17595521
Pubmed	The a subunit isoforms of vacuolar-type proton ATPase exhibit differential distribution in mouse perigastrulation embryos.	ATP6V0A1 ATP6V0A4 ATP6V0A2	7.45e-08	5	69	3	35948619
Pubmed	Aldolase directly interacts with ARNO and modulates cell morphology and acidic vesicle distribution.	ATP6V0A1 ATP6V0A4 ATP6V0A2	1.49e-07	6	69	3	21307348
Pubmed	Optic nerve compression and retinal degeneration in Tcirg1 mutant mice lacking the vacuolar-type H-ATPase a3 subunit.	ATP6V0A1 ATP6V0A4 ATP6V0A2	2.60e-07	7	69	3	20711468
Pubmed	Structure and Roles of V-type ATPases.	ATP6V0A1 ATP6V0A4 ATP6V0A2	2.11e-06	13	69	3	32001091
Pubmed	Molecular cloning and characterization of mouse St7r (St7-like, St7l).	ST7 ST7L	3.88e-06	2	69	2	12060862
Pubmed	ST7-mediated suppression of tumorigenicity of prostate cancer cells is characterized by remodeling of the extracellular matrix.	ST7 ST7L	3.88e-06	2	69	2	16474848
Pubmed	Structures of a Complete Human V-ATPase Reveal Mechanisms of Its Assembly.	ATP6V0A1 ATP6V0A4 ATP6V0A2	4.98e-06	17	69	3	33065002
Pubmed	The vacuolar (H+)-ATPases--nature's most versatile proton pumps.	ATP6V0A1 ATP6V0A4 ATP6V0A2	1.12e-05	22	69	3	11836511
Pubmed	Proton translocation driven by ATP hydrolysis in V-ATPases.	ATP6V0A1 ATP6V0A4 ATP6V0A2	1.12e-05	22	69	3	12788495
Pubmed	Revised nomenclature for mammalian vacuolar-type H+ -ATPase subunit genes.	ATP6V0A1 ATP6V0A4 ATP6V0A2	1.12e-05	22	69	3	14580332
Pubmed	Neurotransmitter release: the dark side of the vacuolar-H+ATPase.	ATP6V0A1 ATP6V0A4 ATP6V0A2	1.12e-05	22	69	3	14597263
Pubmed	Coupling of rotation and catalysis in F(1)-ATPase revealed by single-molecule imaging and manipulation.	ATP6V0A1 ATP6V0A4 ATP6V0A2	1.12e-05	22	69	3	17662945
Pubmed	From lysosomes to the plasma membrane: localization of vacuolar-type H+ -ATPase with the a3 isoform during osteoclast differentiation.	ATP6V0A1 ATP6V0A2	1.16e-05	3	69	2	12672822
Pubmed	Trpm2 deficiency in microglia attenuates neuroinflammation during epileptogenesis by upregulating autophagy via the AMPK/mTOR pathway.	TRPM2 CX3CR1	1.16e-05	3	69	2	37648036
Pubmed	Three subunit a isoforms of mouse vacuolar H(+)-ATPase. Preferential expression of the a3 isoform during osteoclast differentiation.	ATP6V0A1 ATP6V0A2	1.16e-05	3	69	2	10722719
Pubmed	Molecular cloning and expression of three isoforms of the 100-kDa a subunit of the mouse vacuolar proton-translocating ATPase.	ATP6V0A1 ATP6V0A2	1.16e-05	3	69	2	10702241
Pubmed	Acetylcholine-producing NK cells attenuate CNS inflammation via modulation of infiltrating monocytes/macrophages.	CHRFAM7A CX3CR1	1.16e-05	3	69	2	28696300
Pubmed	The function of vacuolar ATPase (V-ATPase) a subunit isoforms in invasiveness of MCF10a and MCF10CA1a human breast cancer cells.	ATP6V0A1 ATP6V0A4	1.16e-05	3	69	2	24072707
Pubmed	The a-subunit of the V-type H+-ATPase interacts with phosphofructokinase-1 in humans.	ATP6V0A1 ATP6V0A4	1.16e-05	3	69	2	12649290
Pubmed	DALRD3 encodes a protein mutated in epileptic encephalopathy that targets arginine tRNAs for 3-methylcytosine modification.	METTL2A METTL2B	1.16e-05	3	69	2	32427860
Pubmed	Receptor-mediated endocytosis: the intracellular journey of transferrin and its receptor.	ATP6V0A1 ATP6V0A4 ATP6V0A2	1.67e-05	25	69	3	2874839
Pubmed	V1 and V0 domains of the human H+-ATPase are linked by an interaction between the G and a subunits.	ATP6V0A1 ATP6V0A4	2.32e-05	4	69	2	17360703
Pubmed	Hair-Cell Mechanotransduction Persists in TRP Channel Knockout Mice.	TRPM2 PKD1L3	2.32e-05	4	69	2	27196058
Pubmed	Mutually exclusive substrate selection strategy by human m3C RNA transferases METTL2A and METTL6.	METTL2A METTL2B	2.32e-05	4	69	2	34268557
Pubmed	Identification of a novel family of putative methyltransferases that interact with human and Drosophila presenilins.	METTL2A METTL2B	2.32e-05	4	69	2	11738826
Pubmed	Differential expression of a subunit isoforms of the vacuolar-type proton pump ATPase in mouse endocrine tissues.	ATP6V0A1 ATP6V0A2	2.32e-05	4	69	2	17497178
Pubmed	Vagus nerve stimulation dampens intestinal inflammation in a murine model of experimental food allergy.	CHRFAM7A CX3CR1	2.32e-05	4	69	2	30897213
Pubmed	Genome-wide association study of maternal and inherited loci for conotruncal heart defects.	SMCHD1 PAPPA	3.86e-05	5	69	2	24800985
Pubmed	Glycosphingolipids are not pivotal receptors for Subtilase cytotoxin in vivo: sensitivity analysis with glycosylation-defective mutant mice.	GAL3ST1 CMAHP	3.86e-05	5	69	2	18996356
Pubmed	Three distinct 3-methylcytidine (m3C) methyltransferases modify tRNA and mRNA in mice and humans.	METTL2A METTL2B	3.86e-05	5	69	2	28655767
Pubmed	Extracellular caspase-6 drives murine inflammatory pain via microglial TNF-α secretion.	CASP6 CX3CR1	3.86e-05	5	69	2	24531553
Pubmed	RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.	MYBBP1A SMCHD1 CHD3 POTEJ THOC2	5.23e-05	202	69	5	24639526
Pubmed	Direct recruitment of H+-ATPase from lysosomes for phagosomal acidification.	ATP6V0A1 ATP6V0A2	8.09e-05	7	69	2	19549681
Pubmed	Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.	CAPN13 MTMR7 ATP6V0A1 KAT5 SSH1 METTL2A METTL2B ATP6V0A2	9.81e-05	730	69	8	34857952
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	DNHD1 MYBBP1A BRPF1 LRBA THOC2	1.05e-04	234	69	5	36243803
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	TRPC4AP TRIO SLC38A9 ST7 INPP5A RALGPS1 WWP2 TRPM2 CHD3 LRBA GALNT7	1.59e-04	1489	69	11	28611215
Pubmed	Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.	MAN2A1 GAL3ST1 ST7 SMCHD1 WWP2 ALG8 WDFY3 LRBA ATP6V0A2	2.43e-04	1061	69	9	33845483
Pubmed	Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.	RPAP1 SSH1 HEATR5A CCDC191	2.49e-04	153	69	4	10718198
Pubmed	Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.	MYBBP1A SMCHD1 CHD3 TEX10 THOC2	2.53e-04	283	69	5	30585729
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	NDST1 RPAP1 SSH1 TRIO XPO6 RALGPS1 PCNX1 WDFY3 LRBA	3.27e-04	1105	69	9	35748872
Pubmed	Evidence for the interaction of the regulatory protein Ki-1/57 with p53 and its interacting proteins.	KAT5 CHD3	3.48e-04	14	69	2	16455055
Pubmed	RNF11 sequestration of the E3 ligase SMURF2 on membranes antagonizes SMAD7 down-regulation of transforming growth factor β signaling.	WWP2 DZIP3	5.18e-04	17	69	2	28292929
Pubmed	The Presynaptic v-ATPase Reversibly Disassembles and Thereby Modulates Exocytosis but Is Not Part of the Fusion Machinery.	ATP6V0A1 ATP6V0A4	5.18e-04	17	69	2	28793259
Pubmed	Characterization of long cDNA clones from human adult spleen. II. The complete sequences of 81 cDNA clones.	DNHD1 TRPC4AP	5.18e-04	17	69	2	12693554
Pubmed	Introduction: V-ATPases 1992-1998.	ATP6V0A1 ATP6V0A4	5.81e-04	18	69	2	10340843
Pubmed	Animal plasma membrane energization by proton-motive V-ATPases.	ATP6V0A1 ATP6V0A4	5.81e-04	18	69	2	10440860
Pubmed	The vacuolar H+-ATPase: a universal proton pump of eukaryotes.	ATP6V0A1 ATP6V0A4	5.81e-04	18	69	2	9210392
Pubmed	RORalpha coordinates reciprocal signaling in cerebellar development through sonic hedgehog and calcium-dependent pathways.	KAT5 INPP5A	5.81e-04	18	69	2	14687547
Pubmed	Vacuolar and plasma membrane proton-adenosinetriphosphatases.	ATP6V0A1 ATP6V0A4	5.81e-04	18	69	2	10221984
Pubmed	Structure and properties of the vacuolar (H+)-ATPases.	ATP6V0A1 ATP6V0A4	5.81e-04	18	69	2	10224039
Pubmed	Structure, function and regulation of the vacuolar (H+)-ATPase.	ATP6V0A1 ATP6V0A4	6.49e-04	19	69	2	9442887
Pubmed	Unravelling the complex genetics of cleft lip in the mouse model.	METTL2A METTL2B	6.49e-04	19	69	2	11353389
Pubmed	Ubiquitous and kidney-specific subunits of vacuolar H+-ATPase are differentially expressed during nephrogenesis.	ATP6V0A1 ATP6V0A4	6.49e-04	19	69	2	16177003
Pubmed	Global mapping of herpesvirus-host protein complexes reveals a transcription strategy for late genes.	ATP6V0A1 XPO6 WWP2 CHD3 TEX10 ANKZF1	6.67e-04	533	69	6	25544563
Pubmed	Lipofuscin is formed independently of macroautophagy and lysosomal activity in stress-induced prematurely senescent human fibroblasts.	ATP6V0A1 ATP6V0A2	7.20e-04	20	69	2	22982048
Pubmed	Rapid identification of 14-3-3-binding proteins by protein microarray analysis.	MCM10 ANKZF1	7.95e-04	21	69	2	16260042
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	MYBBP1A RPAP1 SSH1 XPO6 BRPF1 CHD3 THOC2	8.58e-04	774	69	7	15302935
Pubmed	Large-scale proteomics and phosphoproteomics of urinary exosomes.	DNHD1 EYS ATP6V0A1 MAN2A1 ATP6V0A4 PKD1L3 ZDHHC1 RUSC2	8.93e-04	1016	69	8	19056867
Pubmed	Non-EST-based prediction of novel alternatively spliced cassette exons with cell signaling function in Caenorhabditis elegans and human.	VPS8 WDFY3	1.04e-03	24	69	2	17452356
Pubmed	Molecular genetics of successful smoking cessation: convergent genome-wide association study results.	TRIO SERPINA2 WDFY4	1.08e-03	101	69	3	18519826
Pubmed	Effect of N-(3-phenyl-2-propenyl)-1-deoxynojirimycin on the lectin binding to HIV-1 glycoproteins.	GLT8D2 MAN2A1	1.13e-03	25	69	2	2283726
Pubmed	Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	XPO6 RALGPS1 RUSC2	1.18e-03	104	69	3	9205841
Pubmed	Site-specific N-glycosylation and oligosaccharide structures of recombinant HIV-1 gp120 derived from a baculovirus expression system.	GLT8D2 MAN2A1	1.22e-03	26	69	2	8218172
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	RPAP1 VPS8 DZIP3 HEATR5A RUSC2	1.30e-03	407	69	5	12693553
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	MYBBP1A DZIP3 CHD3 ANKRD50 GALNT7 THOC2 WDFY4 ATP6V0A2	1.35e-03	1084	69	8	11544199
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	MYBBP1A SMCHD1 WWP2 TRPM2 CHD3 POTEJ TEX10 THOC2 ANKZF1	1.51e-03	1371	69	9	36244648
Pubmed	A genetic approach to Mammalian glycan function.	NDST1 MAN2A1	1.63e-03	30	69	2	12676797
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	KAT5 SMCHD1 DZIP3 LRBA MCM10 THOC2	1.77e-03	645	69	6	25281560
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	RPAP1 CHD3 ANKRD50 ANKZF1 RUSC2 CEMIP	1.84e-03	650	69	6	38777146
Pubmed	A Role for Sensory end Organ-Derived Signals in Regulating Muscle Spindle Proprioceptor Phenotype.	CACNA1I HEATR5A	1.85e-03	32	69	2	30926747
Pubmed	The p97/VCP segregase is essential for arsenic-induced degradation of PML and PML-RARA.	MYBBP1A KAT5 TEX10 THOC2	1.85e-03	262	69	4	36880596
Pubmed	Regulation of ETAA1-mediated ATR activation couples DNA replication fidelity and genome stability.	RPAP1 BRPF1 MCM10	1.86e-03	122	69	3	31615875
Pubmed	A quantitative analysis of the spatiotemporal pattern of transient receptor potential gene expression in the developing mouse cochlea.	TRPM2 PKD1L3	1.97e-03	33	69	2	19834762
Interaction	HLA-DQA1 interactions	ATP6V0A1 MAN2A1 SLC38A9 ST7 GALNT7 ATP6V0A2	6.85e-06	135	69	6	int:HLA-DQA1
Interaction	ATP6V0D1 interactions	ATP6V0A1 SLC38A9 ATP6V0A4 THOC2 WDFY4 ATP6V0A2	4.09e-05	185	69	6	int:ATP6V0D1
Interaction	CYTH2 interactions	MTMR7 ATP6V0A1 ATP6V0A4 ATP6V0A2	4.33e-05	57	69	4	int:CYTH2
Interaction	GPR17 interactions	SLC38A9 XPO6 VPS8 ALG8 HEATR5A WDFY3 LRBA	5.13e-05	283	69	7	int:GPR17
Interaction	ATP6V0D2 interactions	ATP6V0A1 ATP6V0A4 WDFY4 ATP6V0A2	6.85e-05	64	69	4	int:ATP6V0D2
Interaction	ATP6V1F interactions	ATP6V0A1 ST7 ATP6V0A4 WDFY4 ATP6V0A2	7.20e-05	126	69	5	int:ATP6V1F
GeneFamily	WD repeat domain containing\|BEACH domain containing	WDFY3 LRBA WDFY4	1.65e-06	9	50	3	1230
GeneFamily	V-type ATPases	ATP6V0A1 ATP6V0A4 ATP6V0A2	3.39e-05	23	50	3	415
GeneFamily	Phosphoinositide phosphatases	MTMR7 INPP5A	3.53e-03	32	50	2	1079
GeneFamily	Methyltransferase like	METTL2A METTL2B	3.75e-03	33	50	2	963
GeneFamily	Sulfotransferases, membrane bound	NDST1 GAL3ST1	4.69e-03	37	50	2	763
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	MAN2A1 PCNX1 HEATR5A WDFY3 ANKRD50 THOC2	5.52e-07	193	69	6	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
Disease	autosomal recessive osteopetrosis 1 (implicated_via_orthology)	ATP6V0A1 ATP6V0A4 ATP6V0A2	1.07e-07	5	66	3	DOID:0110942 (implicated_via_orthology)
Disease	renal tubular acidosis (implicated_via_orthology)	ATP6V0A1 ATP6V0A4 ATP6V0A2	5.94e-07	8	66	3	DOID:14219 (implicated_via_orthology)
Disease	Chediak-Higashi syndrome (implicated_via_orthology)	WDFY3 WDFY4	2.95e-05	4	66	2	DOID:2935 (implicated_via_orthology)
Disease	periprosthetic osteolysis, disease progression measurement	INPP5A CEMIP	5.08e-04	15	66	2	EFO_0008336, EFO_0009761
Disease	status epilepticus (implicated_via_orthology)	CASP6 CX3CR1	1.01e-03	21	66	2	DOID:1824 (implicated_via_orthology)
Disease	cerebral amyloid deposition measurement	PAPPA WDFY3 ST7L	1.28e-03	95	66	3	EFO_0007707
Disease	airway responsiveness measurement	DZIP3 WDFY4	1.32e-03	24	66	2	EFO_0006897
Disease	diastolic blood pressure, alcohol drinking	KAT5 FES ST7L	2.37e-03	118	66	3	EFO_0004329, EFO_0006336
Disease	colorectal adenoma	FBXL13 SSH1	2.49e-03	33	66	2	EFO_0005406
Disease	systolic blood pressure, alcohol drinking	EYS KAT5 FES	2.99e-03	128	66	3	EFO_0004329, EFO_0006335
Disease	gestational age	EYS INPP5A PCNX1	3.69e-03	138	66	3	EFO_0005112

Protein segments in the cluster

Peptide	Gene	Start	Entry
FWHRYFYKVHQLEQE	BSDC1	186	Q9NW68
FWTHYLINEKGLHNA	CX3CR1	86	P49238
EEFARLWKRLVHYQH	CAPN13	561	Q6MZZ7
LWKRLVHYQHVFQKV	CAPN13	566	Q6MZZ7
KQFYCREWVFHKLQH	ANKRD50	21	Q9ULJ7
LFHYSFAEWLLDVKH	ANKRD50	406	Q9ULJ7
LTDFHWVRQLKYHLG	DNHD1	1596	Q96M86
IRHFIAYKNQDHGAW	CEMIP	781	Q8WUJ3
YKFQTGSRFHAILWH	RALGPS1	521	Q5JS13
WFLKNVYLIHQHLCY	EYS	446	Q5T1H1
HFALHKTLEFFWRQN	MAN2A1	321	Q16706
EKDWISFGHKFNHRY	MTMR7	371	Q9Y216
HYIDFNKRLDEWVTH	KAT5	46	Q92993
IALIFNHERFFWHLT	CASP6	46	P55212
HQATFVNALHLYLWL	PCNX1	26	Q96RV3
KNWLREFYQVVHTHK	INPP5A	31	Q14642
FYKIHENGFFKDRHW	METTL2B	81	Q6P1Q9
TNKVFHIWKYDNFAH	NIPSNAP3B	81	Q9BS92
HIWKYDNFAHRAEVR	NIPSNAP3B	86	Q9BS92
YTFKHLVRFLHSWTN	NDST1	541	P52848
VLFYNDFNRWHHEYQ	LRBA	2846	P50851
YSEHFLQEAKLLHWN	GLT8D2	301	Q9H1C3
QHEYHWHDGVKRFFK	MCM10	801	Q7L590
NHNYRGYIEHFSLWK	PAPPA	246	Q13219
IYQHFQFQLLIQHLW	CHRFAM7A	6	Q494W8
LIHKNVLESYYNHLW	DZIP3	426	Q86Y13
WTYHLVQFADLLLNH	MYBBP1A	541	Q9BQG0
FYKIHENGFFKDRHW	METTL2A	81	Q96IZ6
HLYRHFNASFWRKVE	GAL3ST1	306	Q99999
FIKRQARHHPFFLYW	GALNS	216	P34059
AFDLYKSWLIYHNQH	SERPINA2	61	P20848
NAKLHYYNSWALILH	HEATR5A	1486	Q86XA9
EQREHYKLDWHRFNL	ANKZF1	86	Q9H8Y5
DYWEKLLRHHYEQQQ	CHD3	1316	Q12873
KEWQYFKNLHRFTHI	GALNT7	606	Q86SF2
AANYRWVHHKYNFDN	CACNA1I	1351	Q9P0X4
QKRYFAAWHKLILDH	CCDC191	326	Q8NCU4
NIFSQHTFKYWKERH	IFNK	96	Q9P0W0
TCYNFRLQKSVFHHW	FBXL13	46	Q8NEE6
WHHIQNLDSFFTKIY	ATG9B	186	Q674R7
SQILLIYAWHFHEQR	CST9L	21	Q9H4G1
FKAVRLGFHLEFHWF	SLC38A9	331	Q8NBW4
LWKLFAHHNRYVLGV	FES	176	P07332
RSLEFWFNHLYNHED	RUSC2	1116	Q8N2Y8
HIQYLKNYFHLWTRQ	SMCHD1	331	A6NHR9
KNYFHLWTRQLAHIY	SMCHD1	336	A6NHR9
NLLRFWQQHYLHKDK	TRPC4AP	731	Q8TEL6
NRFYLHQAIWKTFSH	PKD1L3	1306	Q7Z443
EKIWHHTFYNELRVA	POTEJ	746	P0CG39
KHLHLYYDLINFTWI	VPS8	396	Q8N3P4
AIAYAFFHLAHWKRV	ST7	441	Q9NRC1
HWNEAYHFINKAKRN	SSH1	371	Q8WYL5
HLYLVLFFDNKRTWQ	BRPF1	1141	P55201
WNFGLLIVDHIHFQY	ALG8	151	Q9BVK2
YHHLFWNHFQIKLPL	CMAHP	446	Q9Y471
RWKYHQFRFLCHSNA	WWP2	496	O00308
AFTWFSYLTQHKRIH	ZNF695	416	Q8IW36
DQLDYENFRHVVHKW	THOC2	1086	Q8NI27
HLHEWIDLIFGYKQQ	WDFY3	2906	Q8IZQ1
QIWKFQRHDLIEEYH	TRPM2	1061	O94759
NLHHWIDLIFGYKQQ	WDFY4	2751	Q6ZS81
NGFSLWEHLVKLNYH	TTC41P	1126	Q6P2S7
SWLRKNYLIDFKHHF	TEX10	381	Q9NXF1
SEAIAYAFFHLQHWK	ST7L	436	Q8TDW4
YAFFHLQHWKRIEGA	ST7L	441	Q8TDW4
WALRHEYHLQYLALA	RPAP1	946	Q9BWH6
HALRLHWVEFQNKFY	ATP6V0A1	801	Q93050
LRLHWVEFQNKFYVG	ATP6V0A4	806	Q9HBG4
WGHRILHYSFQFLEN	XKR3	341	Q5GH77
LLFRTLHHNWRYFFK	XPO6	941	Q96QU8
LHHNWRYFFKSTVLA	XPO6	946	Q96QU8
FGNIHQIYDWHRDFF	TRIO	2016	O75962
KHLRVAAHDLTWFQY	UGT2A2	481	P0DTE5
HFEVLKNHTDVWFVF	ZDHHC1	216	Q8WTX9
HAIRLHWVEFQNKFY	ATP6V0A2	816	Q9Y487