Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	semaphorin receptor binding	SEMA3A SEMA6C SEMA6B	4.16e-05	23	59	3	GO:0030215
GeneOntologyMolecularFunction	chemorepellent activity	SEMA3A SEMA6C SEMA6B	8.48e-05	29	59	3	GO:0045499
GeneOntologyBiologicalProcess	cell morphogenesis involved in neuron differentiation	SEMA3A SEMA6C SEMA6B LHX2 MNX1 MYO7A LRP2 RTN4RL1 ADAM10 TCTN1 NOTCH3 RBFOX2	9.12e-07	748	58	12	GO:0048667
GeneOntologyBiologicalProcess	axon guidance	SEMA3A SEMA6C SEMA6B LHX2 MNX1 LRP2 RTN4RL1 NOTCH3	1.27e-06	285	58	8	GO:0007411
GeneOntologyBiologicalProcess	neuron projection guidance	SEMA3A SEMA6C SEMA6B LHX2 MNX1 LRP2 RTN4RL1 NOTCH3	1.30e-06	286	58	8	GO:0097485
GeneOntologyBiologicalProcess	embryo development	SEMA3A LHX2 FOXD3 HOXC9 MNX1 HOXD13 MYO7A GLI1 HPN HS6ST1 LRP2 MMP14 ADAM10 HECTD1 TCTN1 WDTC1	1.38e-06	1437	58	16	GO:0009790
GeneOntologyBiologicalProcess	cell morphogenesis	SEMA3A SEMA6C SEMA6B LHX2 MNX1 MYO7A HPN LRP2 RTN4RL1 ADAM10 JMJD1C TCTN1 NOTCH3 RBFOX2	4.05e-06	1194	58	14	GO:0000902
GeneOntologyBiologicalProcess	head development	SEMA3A SLC32A1 SEMA6B LHX2 GLI1 LRP2 RTN4RL1 GRIN2D MMP14 TCTN1 NOTCH3 RBFOX2	7.64e-06	919	58	12	GO:0060322
GeneOntologyBiologicalProcess	forebrain development	SEMA3A SLC32A1 SEMA6B LHX2 GLI1 LRP2 RTN4RL1 TCTN1 NOTCH3	8.34e-06	489	58	9	GO:0030900
GeneOntologyBiologicalProcess	neuron development	SEMA3A SEMA6C SEMA6B LHX2 MNX1 MYO7A HS6ST1 LRP2 MPDZ RTN4RL1 ACP4 ADAM10 TCTN1 NOTCH3 RBFOX2	8.75e-06	1463	58	15	GO:0048666
GeneOntologyBiologicalProcess	neuron projection development	SEMA3A SEMA6C SEMA6B LHX2 MNX1 MYO7A LRP2 MPDZ RTN4RL1 ACP4 ADAM10 TCTN1 NOTCH3 RBFOX2	9.41e-06	1285	58	14	GO:0031175
GeneOntologyBiologicalProcess	reproductive structure development	SEMA3A HOXD13 GLI1 LRP2 NR5A1 MMP14 JMJD1C PGR	1.12e-05	383	58	8	GO:0048608
GeneOntologyBiologicalProcess	neuron projection morphogenesis	SEMA3A SEMA6C SEMA6B LHX2 MNX1 LRP2 RTN4RL1 ADAM10 TCTN1 NOTCH3 RBFOX2	1.23e-05	802	58	11	GO:0048812
GeneOntologyBiologicalProcess	reproductive system development	SEMA3A HOXD13 GLI1 LRP2 NR5A1 MMP14 JMJD1C PGR	1.23e-05	388	58	8	GO:0061458
GeneOntologyBiologicalProcess	negative chemotaxis	SEMA3A SEMA6C SEMA6B RTN4RL1	1.27e-05	51	58	4	GO:0050919
GeneOntologyBiologicalProcess	plasma membrane bounded cell projection morphogenesis	SEMA3A SEMA6C SEMA6B LHX2 MNX1 LRP2 RTN4RL1 ADAM10 TCTN1 NOTCH3 RBFOX2	1.49e-05	819	58	11	GO:0120039
GeneOntologyBiologicalProcess	cell projection morphogenesis	SEMA3A SEMA6C SEMA6B LHX2 MNX1 LRP2 RTN4RL1 ADAM10 TCTN1 NOTCH3 RBFOX2	1.62e-05	826	58	11	GO:0048858
GeneOntologyBiologicalProcess	male sex differentiation	SEMA3A HOXD13 LRP2 NR5A1 MMP14 JMJD1C	1.99e-05	199	58	6	GO:0046661
GeneOntologyBiologicalProcess	positive regulation of cell migration	SEMA3A SEMA6C SEMA6B GLI1 TMEM102 ITGA2B MMP14 ADAM10 PGR FAM83H	2.04e-05	691	58	10	GO:0030335
GeneOntologyBiologicalProcess	brain development	SEMA3A SLC32A1 SEMA6B LHX2 GLI1 LRP2 RTN4RL1 GRIN2D TCTN1 NOTCH3 RBFOX2	2.32e-05	859	58	11	GO:0007420
GeneOntologyBiologicalProcess	tube development	LHX2 MNX1 HOXD13 GLI1 HS6ST1 LRP2 ITGA2B MMP14 HECTD1 JMJD1C TCTN1 NOTCH3 PGR FOXL1	2.51e-05	1402	58	14	GO:0035295
GeneOntologyBiologicalProcess	axonogenesis	SEMA3A SEMA6C SEMA6B LHX2 MNX1 LRP2 RTN4RL1 TCTN1 NOTCH3	2.66e-05	566	58	9	GO:0007409
GeneOntologyBiologicalProcess	embryonic morphogenesis	LHX2 HOXC9 HOXD13 MYO7A GLI1 HPN LRP2 MMP14 HECTD1 TCTN1	2.66e-05	713	58	10	GO:0048598
GeneOntologyBiologicalProcess	positive regulation of cell motility	SEMA3A SEMA6C SEMA6B GLI1 TMEM102 ITGA2B MMP14 ADAM10 PGR FAM83H	3.07e-05	725	58	10	GO:2000147
GeneOntologyBiologicalProcess	positive regulation of locomotion	SEMA3A SEMA6C SEMA6B GLI1 TMEM102 ITGA2B MMP14 ADAM10 PGR FAM83H	3.73e-05	742	58	10	GO:0040017
GeneOntologyBiologicalProcess	chordate embryonic development	LHX2 FOXD3 HOXC9 MNX1 HS6ST1 LRP2 MMP14 ADAM10 HECTD1 TCTN1 WDTC1	3.79e-05	906	58	11	GO:0043009
GeneOntologyBiologicalProcess	animal organ morphogenesis	SEMA3A PAPPA2 HOXC9 HOXD13 MYO7A GLI1 HPN LRP2 PEX7 ACP4 MMP14 GAA PGR	3.99e-05	1269	58	13	GO:0009887
GeneOntologyBiologicalProcess	embryo development ending in birth or egg hatching	LHX2 FOXD3 HOXC9 MNX1 HS6ST1 LRP2 MMP14 ADAM10 HECTD1 TCTN1 WDTC1	4.76e-05	929	58	11	GO:0009792
GeneOntologyBiologicalProcess	regionalization	SEMA3A LHX2 HOXC9 MNX1 HOXD13 GLI1 LRP2 TCTN1	5.44e-05	478	58	8	GO:0003002
GeneOntologyBiologicalProcess	sex differentiation	SEMA3A HOXD13 LRP2 NR5A1 MMP14 JMJD1C PGR	5.65e-05	352	58	7	GO:0007548
GeneOntologyBiologicalProcess	axon development	SEMA3A SEMA6C SEMA6B LHX2 MNX1 LRP2 RTN4RL1 TCTN1 NOTCH3	7.07e-05	642	58	9	GO:0061564
GeneOntologyBiologicalProcess	central nervous system development	SEMA3A SLC32A1 SEMA6B LHX2 MNX1 GLI1 LRP2 RTN4RL1 GRIN2D TCTN1 NOTCH3 RBFOX2	1.03e-04	1197	58	12	GO:0007417
GeneOntologyBiologicalProcess	pattern specification process	SEMA3A LHX2 HOXC9 MNX1 HOXD13 GLI1 LRP2 TCTN1	1.06e-04	526	58	8	GO:0007389
GeneOntologyBiologicalProcess	male gonad development	SEMA3A LRP2 NR5A1 MMP14 JMJD1C	1.19e-04	171	58	5	GO:0008584
GeneOntologyBiologicalProcess	development of primary male sexual characteristics	SEMA3A LRP2 NR5A1 MMP14 JMJD1C	1.22e-04	172	58	5	GO:0046546
GeneOntologyBiologicalProcess	gland morphogenesis	SEMA3A HOXD13 GLI1 HPN PGR	1.43e-04	178	58	5	GO:0022612
GeneOntologyBiologicalProcess	embryonic organ development	FOXD3 HOXC9 MYO7A GLI1 HPN HS6ST1 MMP14 HECTD1	1.65e-04	561	58	8	GO:0048568
GeneOntologyBiologicalProcess	gonad development	SEMA3A LRP2 NR5A1 MMP14 JMJD1C PGR	1.67e-04	292	58	6	GO:0008406
GeneOntologyBiologicalProcess	epithelium development	SEMA3A LHX2 MNX1 HOXD13 MYO7A GLI1 LRP2 NR5A1 MMP14 HECTD1 JMJD1C TCTN1 PGR	1.76e-04	1469	58	13	GO:0060429
GeneOntologyBiologicalProcess	development of primary sexual characteristics	SEMA3A LRP2 NR5A1 MMP14 JMJD1C PGR	1.83e-04	297	58	6	GO:0045137
GeneOntologyBiologicalProcess	tissue morphogenesis	SEMA3A LHX2 HOXD13 LRP2 MMP14 HECTD1 TCTN1 PGR FOXL1	2.28e-04	750	58	9	GO:0048729
GeneOntologyBiologicalProcess	dorsal/ventral pattern formation	LHX2 MNX1 GLI1 TCTN1	2.34e-04	107	58	4	GO:0009953
GeneOntologyBiologicalProcess	neural tube development	LHX2 MNX1 LRP2 HECTD1 TCTN1	2.58e-04	202	58	5	GO:0021915
GeneOntologyBiologicalProcess	tube morphogenesis	LHX2 HOXD13 GLI1 HS6ST1 LRP2 ITGA2B MMP14 HECTD1 TCTN1 NOTCH3 PGR	2.59e-04	1125	58	11	GO:0035239
GeneOntologyBiologicalProcess	positive regulation of male gonad development	SEMA3A NR5A1	2.76e-04	9	58	2	GO:2000020
GeneOntologyBiologicalProcess	morphogenesis of an epithelium	SEMA3A LHX2 HOXD13 LRP2 MMP14 HECTD1 TCTN1 PGR	3.21e-04	619	58	8	GO:0002009
GeneOntologyBiologicalProcess	telencephalon development	SEMA3A SLC32A1 SEMA6B LHX2 RTN4RL1 TCTN1	3.33e-04	332	58	6	GO:0021537
GeneOntologyBiologicalProcess	semaphorin-plexin signaling pathway	SEMA3A SEMA6C SEMA6B	4.23e-04	52	58	3	GO:0071526
GeneOntologyBiologicalProcess	neuromuscular process	MYO7A GRIN2D DMPK GAA RBFOX2	4.23e-04	225	58	5	GO:0050905
GeneOntologyBiologicalProcess	positive regulation of gonad development	SEMA3A NR5A1	5.04e-04	12	58	2	GO:1905941
GeneOntologyBiologicalProcess	regulation of male gonad development	SEMA3A NR5A1	5.04e-04	12	58	2	GO:2000018
GeneOntologyBiologicalProcess	artery development	LRP2 HECTD1 GAA NOTCH3	5.35e-04	133	58	4	GO:0060840
GeneOntologyBiologicalProcess	neural tube formation	LHX2 LRP2 HECTD1 TCTN1	5.51e-04	134	58	4	GO:0001841
GeneOntologyBiologicalProcess	chemotaxis	SEMA3A SEMA6C SEMA6B LRP2 RTN4RL1 TMEM102 ADAM10	5.94e-04	517	58	7	GO:0006935
GeneOntologyBiologicalProcess	taxis	SEMA3A SEMA6C SEMA6B LRP2 RTN4RL1 TMEM102 ADAM10	6.08e-04	519	58	7	GO:0042330
GeneOntologyBiologicalProcess	cochlea development	MYO7A HPN ADAM10	6.76e-04	61	58	3	GO:0090102
GeneOntologyBiologicalProcess	neural crest cell migration	SEMA3A SEMA6C SEMA6B	7.09e-04	62	58	3	GO:0001755
GeneOntologyBiologicalProcess	mesenchymal cell migration	SEMA3A SEMA6C SEMA6B	7.78e-04	64	58	3	GO:0090497
GeneOntologyBiologicalProcess	positive regulation of T cell chemotaxis	TMEM102 ADAM10	9.09e-04	16	58	2	GO:0010820
GeneOntologyBiologicalProcess	female sex differentiation	LRP2 NR5A1 MMP14 PGR	9.96e-04	157	58	4	GO:0046660
GeneOntologyBiologicalProcess	embryonic epithelial tube formation	LHX2 LRP2 HECTD1 TCTN1	1.04e-03	159	58	4	GO:0001838
GeneOntologyBiologicalProcess	epithelial tube morphogenesis	LHX2 LRP2 MMP14 HECTD1 TCTN1 PGR	1.15e-03	421	58	6	GO:0060562
GeneOntologyBiologicalProcess	regulation of gonad development	SEMA3A NR5A1	1.16e-03	18	58	2	GO:1905939
GeneOntologyBiologicalProcess	neuromuscular process controlling balance	MYO7A GAA RBFOX2	1.19e-03	74	58	3	GO:0050885
GeneOntologyBiologicalProcess	extracellular matrix disassembly	HPN MMP14 ADAM10	1.23e-03	75	58	3	GO:0022617
GeneOntologyBiologicalProcess	negative regulation of neuron projection development	SEMA3A SEMA6C RTN4RL1 ACP4	1.31e-03	169	58	4	GO:0010977
GeneOntologyBiologicalProcess	epithelial tube formation	LHX2 LRP2 HECTD1 TCTN1	1.43e-03	173	58	4	GO:0072175
GeneOntologyBiologicalProcess	regulation of T cell chemotaxis	TMEM102 ADAM10	1.43e-03	20	58	2	GO:0010819
GeneOntologyBiologicalProcess	aorta development	LRP2 HECTD1 GAA	1.49e-03	80	58	3	GO:0035904
GeneOntologyBiologicalProcess	regulation of protein processing	HPN ACP4 MMP14	1.60e-03	82	58	3	GO:0070613
GeneOntologyBiologicalProcess	positive regulation of leukocyte migration	TMEM102 ITGA2B MMP14 ADAM10	1.62e-03	179	58	4	GO:0002687
GeneOntologyBiologicalProcess	respiratory system development	MNX1 GLI1 HS6ST1 MMP14 PGR	1.65e-03	305	58	5	GO:0060541
GeneOntologyBiologicalProcess	positive regulation of lymphocyte chemotaxis	TMEM102 ADAM10	1.73e-03	22	58	2	GO:0140131
GeneOntologyBiologicalProcess	cell growth	SEMA3A PAPPA2 SEMA6C LHX2 HPN MMP14 ADAM10	1.79e-03	625	58	7	GO:0016049
GeneOntologyBiologicalProcess	regulation of protein maturation	HPN ACP4 MMP14	1.83e-03	86	58	3	GO:1903317
GeneOntologyBiologicalProcess	regulation of cell migration	SEMA3A SEMA6C SEMA6B GLI1 TMEM102 ITGA2B MMP14 ADAM10 PGR FAM83H	1.86e-03	1211	58	10	GO:0030334
GeneOntologyBiologicalProcess	tube formation	LHX2 LRP2 HECTD1 TCTN1	1.89e-03	187	58	4	GO:0035148
GeneOntologyBiologicalProcess	morphogenesis of embryonic epithelium	LHX2 LRP2 HECTD1 TCTN1	2.01e-03	190	58	4	GO:0016331
GeneOntologyBiologicalProcess	neural crest cell development	SEMA3A SEMA6C SEMA6B	2.02e-03	89	58	3	GO:0014032
GeneOntologyBiologicalProcess	growth	SEMA3A PAPPA2 SEMA6C LHX2 HOXD13 GLI1 HPN MMP14 ADAM10 WDTC1	2.14e-03	1235	58	10	GO:0040007
GeneOntologyBiologicalProcess	dorsal/ventral neural tube patterning	MNX1 TCTN1	2.24e-03	25	58	2	GO:0021904
GeneOntologyBiologicalProcess	maintenance of protein location in nucleus	NR5A1 PGR	2.42e-03	26	58	2	GO:0051457
Domain	Semaphorin	SEMA3A SEMA6C SEMA6B	3.29e-05	20	59	3	IPR027231
Domain	Sema	SEMA3A SEMA6C SEMA6B	1.26e-04	31	59	3	SM00630
Domain	Semap_dom	SEMA3A SEMA6C SEMA6B	1.26e-04	31	59	3	IPR001627
Domain	Sema	SEMA3A SEMA6C SEMA6B	1.26e-04	31	59	3	PF01403
Domain	SEMA	SEMA3A SEMA6C SEMA6B	1.26e-04	31	59	3	PS51004
Domain	Notch_dom	PAPPA2 NOTCH3	2.04e-04	7	59	2	IPR000800
Domain	Notch	PAPPA2 NOTCH3	2.04e-04	7	59	2	PF00066
Domain	NL	PAPPA2 NOTCH3	2.04e-04	7	59	2	SM00004
Domain	MYTH4	MYO7A ARHGAP39	3.48e-04	9	59	2	PS51016
Domain	MyTH4_dom	MYO7A ARHGAP39	3.48e-04	9	59	2	IPR000857
Domain	MyTH4	MYO7A ARHGAP39	3.48e-04	9	59	2	PF00784
Domain	MyTH4	MYO7A ARHGAP39	3.48e-04	9	59	2	SM00139
Domain	PSI	SEMA3A SEMA6C SEMA6B	3.62e-04	44	59	3	IPR016201
Domain	PSI	SEMA3A SEMA6C SEMA6B	4.13e-04	46	59	3	SM00423
Domain	AT_hook	PRR12 CCDC71	1.14e-03	16	59	2	PF02178
Domain	Hemopexin_CS	HPX MMP14	1.29e-03	17	59	2	IPR018486
Domain	MetalloPept_cat_dom	PAPPA2 MMP14 ADAM10	2.14e-03	81	59	3	IPR024079
Domain	-	PAPPA2 MMP14 ADAM10	2.14e-03	81	59	3	3.40.390.10
Domain	Hemopexin-like_dom	HPX MMP14	2.38e-03	23	59	2	IPR000585
Domain	Hemopexin-like_repeat	HPX MMP14	2.38e-03	23	59	2	IPR018487
Domain	Hemopexin	HPX MMP14	2.38e-03	23	59	2	PF00045
Domain	HEMOPEXIN	HPX MMP14	2.38e-03	23	59	2	PS00024
Domain	-	HPX MMP14	2.38e-03	23	59	2	2.110.10.10
Domain	HEMOPEXIN_2	HPX MMP14	2.38e-03	23	59	2	PS51642
Domain	HX	HPX MMP14	2.38e-03	23	59	2	SM00120
Domain	Homeobox_CS	LHX2 HOXC9 MNX1 HOXD13	2.83e-03	186	59	4	IPR017970
Domain	ZINC_PROTEASE	PAPPA2 MMP14 ADAM10	3.68e-03	98	59	3	PS00142
Domain	Homeodomain-like	SEMA6C LHX2 HOXC9 MNX1 HOXD13	3.93e-03	332	59	5	IPR009057
Domain	-	SEMA3A SEMA6C SEMA6B PEX7 WDTC1	3.98e-03	333	59	5	2.130.10.10
Domain	WD40/YVTN_repeat-like_dom	SEMA3A SEMA6C SEMA6B PEX7 WDTC1	4.09e-03	335	59	5	IPR015943
Domain	HMGI/Y_DNA-bd_CS	PRR12 CCDC71	4.30e-03	31	59	2	IPR000637
Domain	PSI	SEMA6C SEMA6B	4.58e-03	32	59	2	PF01437
Domain	Plexin_repeat	SEMA6C SEMA6B	4.58e-03	32	59	2	IPR002165
Domain	Homeobox	LHX2 HOXC9 MNX1 HOXD13	6.38e-03	234	59	4	PF00046
Domain	HOMEOBOX_1	LHX2 HOXC9 MNX1 HOXD13	6.57e-03	236	59	4	PS00027
Domain	HOX	LHX2 HOXC9 MNX1 HOXD13	6.67e-03	237	59	4	SM00389
Domain	-	HHIPL2 LRP2	6.74e-03	39	59	2	2.120.10.30
Domain	HOMEOBOX_2	LHX2 HOXC9 MNX1 HOXD13	6.86e-03	239	59	4	PS50071
Domain	Homeobox_dom	LHX2 HOXC9 MNX1 HOXD13	6.86e-03	239	59	4	IPR001356
Domain	CYSTEINE_SWITCH	MMP14 ADAM10	7.43e-03	41	59	2	PS00546
Domain	Pept_M10_metallopeptidase	MMP14 ADAM10	8.15e-03	43	59	2	IPR001818
Domain	zf-C4	NR5A1 PGR	9.29e-03	46	59	2	PF00105
Domain	Znf_hrmn_rcpt	NR5A1 PGR	9.29e-03	46	59	2	IPR001628
Domain	Nuclear_hrmn_rcpt	NR5A1 PGR	9.29e-03	46	59	2	IPR001723
Domain	NUCLEAR_REC_DBD_2	NR5A1 PGR	9.29e-03	46	59	2	PS51030
Domain	TF_fork_head_CS_2	FOXD3 FOXL1	9.29e-03	46	59	2	IPR030456
Domain	NUCLEAR_REC_DBD_1	NR5A1 PGR	9.29e-03	46	59	2	PS00031
Domain	ZnF_C4	NR5A1 PGR	9.29e-03	46	59	2	SM00399
Domain	6-blade_b-propeller_TolB-like	HHIPL2 LRP2	9.29e-03	46	59	2	IPR011042
Pubmed	Disrupted dorsal neural tube BMP signaling in the cilia mutant Arl13b hnn stems from abnormal Shh signaling.	LHX2 FOXD3 MNX1 GLI1	2.84e-08	19	59	4	21539826
Pubmed	Human transcription factor protein interaction networks.	PRR12 LHX2 HOXC9 UBAP2 MNX1 BMS1 LRP2 CTBP1 DPF2 RAD54L2 FIGN JMJD1C ZNF503 FOXL1	8.61e-08	1429	59	14	35140242
Pubmed	Hox repertoires for motor neuron diversity and connectivity gated by a single accessory factor, FoxP1.	SEMA3A FOXD3 HOXC9 MNX1	2.95e-07	33	59	4	18662545
Pubmed	Intestinal cell kinase, a protein associated with endocrine-cerebro-osteodysplasia syndrome, is a key regulator of cilia length and Hedgehog signaling.	MNX1 HOXD13 GLI1	1.31e-06	13	59	3	24853502
Pubmed	Planar cell polarity effector gene Fuzzy regulates cilia formation and Hedgehog signal transduction in mouse.	MNX1 HOXD13 GLI1	1.67e-06	14	59	3	19877275
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	SEMA6C SEMA6B PRR12 MYO7A GLI1 GRIN2D MMP14 ESPL1 HECTD1 FAM83H ZNF503	2.19e-06	1105	59	11	35748872
Pubmed	Optic chiasm presentation of Semaphorin6D in the context of Plexin-A1 and Nr-CAM promotes retinal axon midline crossing.	SEMA3A SEMA6C SEMA6B	2.56e-06	16	59	3	22632726
Pubmed	Three Tctn proteins are functionally conserved in the regulation of neural tube patterning and Gli3 processing but not ciliogenesis and Hedgehog signaling in the mouse.	MNX1 GLI1 TCTN1	2.56e-06	16	59	3	28800946
Pubmed	A census of human transcription factors: function, expression and evolution.	LHX2 FOXD3 HOXC9 MNX1 HOXD13 GLI1 NR5A1 DPF2 PGR FOXL1	2.76e-06	908	59	10	19274049
Pubmed	Neuronal ADAM10 Promotes Outgrowth of Small-Caliber Myelinated Axons in the Peripheral Nervous System.	MNX1 ADAM10	2.83e-06	2	59	2	26426268
Pubmed	Steroidogenic Factor 1 Regulation of the Hypothalamic-Pituitary-Ovarian Axis of Adult Female Mice.	NR5A1 PGR	2.83e-06	2	59	2	35247045
Pubmed	The dimer interface of the membrane type 1 matrix metalloproteinase hemopexin domain: crystal structure and biological functions.	HPX MMP14	2.83e-06	2	59	2	21193411
Pubmed	Dlx1&2 and Mash1 transcription factors control MGE and CGE patterning and differentiation through parallel and overlapping pathways.	SEMA3A SLC32A1 LHX2 GLI1 ZNF503	2.88e-06	130	59	5	19386638
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	LHX2 FOXD3 HOXC9 MNX1 GLI1 DPF2 ZBTB3 PGR FOXL1	2.92e-06	709	59	9	22988430
Pubmed	Dlx1&2 and Mash1 transcription factors control striatal patterning and differentiation through parallel and overlapping pathways.	SEMA3A SLC32A1 LHX2 GLI1 ZNF503	3.34e-06	134	59	5	19030180
Pubmed	Neurites from trigeminal ganglion explants grown in vitro are repelled or attracted by tooth-related tissues depending on developmental stage.	SEMA3A SEMA6C SEMA6B	4.41e-06	19	59	3	15051154
Pubmed	Astrocyte-encoded positional cues maintain sensorimotor circuit integrity.	SEMA3A SLC32A1 MNX1	5.18e-06	20	59	3	24776795
Pubmed	Loss of dynein-2 intermediate chain Wdr34 results in defects in retrograde ciliary protein trafficking and Hedgehog signaling in the mouse.	MNX1 HOXD13 GLI1	5.18e-06	20	59	3	28379358
Pubmed	IgSF8: a developmentally and functionally regulated cell adhesion molecule in olfactory sensory neuron axons and synapses.	ITGA2B MMP14 ADAM10	5.18e-06	20	59	3	22687584
Pubmed	Motor neurons use push-pull signals to direct vascular remodeling critical for their connectivity.	SEMA3A SEMA6C MNX1	6.03e-06	21	59	3	36240771
Pubmed	Mouse hitchhiker mutants have spina bifida, dorso-ventral patterning defects and polydactyly: identification of Tulp3 as a novel negative regulator of the Sonic hedgehog pathway.	MNX1 HOXD13 GLI1	6.98e-06	22	59	3	19223390
Pubmed	Broad-minded links cell cycle-related kinase to cilia assembly and hedgehog signal transduction.	MNX1 HOXD13 GLI1	6.98e-06	22	59	3	20159594
Pubmed	Loss of Tctn3 causes neuronal apoptosis and neural tube defects in mice.	MNX1 GLI1 TCTN1	6.98e-06	22	59	3	29725084
Pubmed	Patched 1 is a crucial determinant of asymmetry and digit number in the vertebrate limb.	HOXD13 GLI1 ZNF503	8.02e-06	23	59	3	19783740
Pubmed	Sema6B, Sema6C, and Sema6D expression and function during mammalian retinal development.	SEMA6C SEMA6B	8.48e-06	3	59	2	23646199
Pubmed	Endometrial Expression of Steroidogenic Factor 1 Promotes Cystic Glandular Morphogenesis.	NR5A1 PGR	8.48e-06	3	59	2	27018534
Pubmed	Lymphatic endothelium stimulates melanoma metastasis and invasion via MMP14-dependent Notch3 and β1-integrin activation.	MMP14 NOTCH3	8.48e-06	3	59	2	29712618
Pubmed	CD44 binding through the hemopexin-like domain is critical for its shedding by membrane-type 1 matrix metalloproteinase.	HPX MMP14	8.48e-06	3	59	2	15558018
Pubmed	Notch1 Autoactivation via Transcriptional Regulation of Furin, Which Sustains Notch1 Signaling by Processing Notch1-Activating Proteases ADAM10 and Membrane Type 1 Matrix Metalloproteinase.	MMP14 ADAM10	8.48e-06	3	59	2	26283728
Pubmed	MT1-MMP and ADAM10/17 exhibit a remarkable overlap of shedding properties.	MMP14 ADAM10	8.48e-06	3	59	2	35944080
Pubmed	GLI3 resides at the intersection of hedgehog and androgen action to promote male sex differentiation.	GLI1 NR5A1 NOTCH3	9.15e-06	24	59	3	32497091
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	FOXD3 HOXD13 GLI1 BMS1 JMJD1C SH2B1 GAA NOTCH3 FOXL1	1.34e-05	857	59	9	25609649
Pubmed	An inducible CRISPR/Cas9 screen identifies DTX2 as a transcriptional regulator of human telomerase.	PRR12 CTBP1 RAD54L2 JMJD1C NOTCH3	1.40e-05	180	59	5	35198878
Pubmed	An atlas of combinatorial transcriptional regulation in mouse and man.	LHX2 HOXC9 HOXD13 GLI1 CTBP1 NR5A1 DPF2 ZBTB3 RBFOX2	1.61e-05	877	59	9	20211142
Pubmed	Noggin is required for correct guidance of dorsal root ganglion axons.	SEMA3A SEMA6C SEMA6B	1.64e-05	29	59	3	12435358
Pubmed	Identification of C-Terminal Binding Protein 1 as a Novel NMDA Receptor Interactor.	CTBP1 GRIN2D	1.69e-05	4	59	2	30284099
Pubmed	Association analysis of Notch pathway signalling genes in diabetic nephropathy.	ADAM10 NOTCH3	1.69e-05	4	59	2	21103979
Pubmed	Novel ATPase of SNF2-like protein family interacts with androgen receptor and modulates androgen-dependent transcription.	RAD54L2 PGR	1.69e-05	4	59	2	12058073
Pubmed	Sf3b4 regulates chromatin remodeler splicing and Hox expression.	HOXC9 HOXD13 JMJD1C	2.22e-05	32	59	3	37167859
Pubmed	Ctip2 controls the differentiation of medium spiny neurons and the establishment of the cellular architecture of the striatum.	SEMA3A FIGN ZNF503	2.44e-05	33	59	3	18199763
Pubmed	The transcriptional control of trunk neural crest induction, survival, and delamination.	LHX2 FOXD3 MNX1	2.67e-05	34	59	3	15691760
Pubmed	Semaphorins guide the entry of dendritic cells into the lymphatics by activating myosin II.	SEMA3A SEMA6C	2.82e-05	5	59	2	20512151
Pubmed	α-Toxin Induces Platelet Aggregation and Liver Injury during Staphylococcus aureus Sepsis.	ITGA2B ADAM10	2.82e-05	5	59	2	30033122
Pubmed	Expression of progesterone receptor, estrogen receptors α and β, and kisspeptin in the hypothalamus during perinatal development of gonad-lacking steroidogenic factor-1 knockout mice.	NR5A1 PGR	2.82e-05	5	59	2	30776325
Pubmed	Regulation of Gli2 and Gli3 activities by an amino-terminal repression domain: implication of Gli2 and Gli3 as primary mediators of Shh signaling.	LHX2 GLI1	2.82e-05	5	59	2	10433919
Pubmed	Interaction network of human early embryonic transcription factors.	PRR12 MNX1 CTBP1 DPF2 RAD54L2 ZNF503	2.91e-05	351	59	6	38297188
Pubmed	Global control of motor neuron topography mediated by the repressive actions of a single hox gene.	SEMA3A HOXC9 MNX1	3.18e-05	36	59	3	20826310
Pubmed	Isolation and Characterization of Fetal Leydig Progenitor Cells of Male Mice.	GLI1 NR5A1 NOTCH3	3.46e-05	37	59	3	26697723
Pubmed	PRC1 sustains the integrity of neural fate in the absence of PRC2 function.	LHX2 HOXC9 MNX1	3.75e-05	38	59	3	34994686
Pubmed	Sonic hedgehog is not required for polarising activity in the Doublefoot mutant mouse limb bud.	HOXD13 GLI1	4.23e-05	6	59	2	9425131
Pubmed	Semaphorin 3A-Neuropilin-1 signaling regulates peripheral axon fasciculation and pathfinding but not developmental cell death patterns.	SEMA3A MNX1	4.23e-05	6	59	2	20345923
Pubmed	A dynamic expression survey identifies transcription factors relevant in mouse digestive tract development.	HOXC9 HOXD13 NR5A1 PGR	4.96e-05	118	59	4	16971476
Pubmed	Identification and functional characterization of transcriptional activators in human cells.	PRR12 HOXD13 CTBP1 DPF2 JMJD1C ZNF503	5.84e-05	398	59	6	35016035
Pubmed	A differential developmental pattern of spinal interneuron apoptosis during synaptogenesis: insights from genetic analyses of the protocadherin-gamma gene cluster.	SLC32A1 LHX2 MNX1	5.84e-05	44	59	3	19029045
Pubmed	Megalin mediates the influence of sonic hedgehog on oligodendrocyte precursor cell migration and proliferation during development.	GLI1 LRP2	5.91e-05	7	59	2	22354480
Pubmed	Distinctive functioning of STARD1 in the fetal Leydig cells compared to adult Leydig and adrenal cells. Impact of Hedgehog signaling via the primary cilium.	GLI1 NR5A1	5.91e-05	7	59	2	33864885
Pubmed	FoxF1 and FoxL1 link hedgehog signaling and the control of epithelial proliferation in the developing stomach and intestine.	GLI1 FOXL1	5.91e-05	7	59	2	19049965
Pubmed	Fetal adrenal capsular cells serve as progenitor cells for steroidogenic and stromal adrenocortical cell lineages in M. musculus.	GLI1 NR5A1	5.91e-05	7	59	2	24131628
Pubmed	Differential regulation of gene expression in the digit forming area of the mouse limb bud by SHH and gremlin 1/FGF-mediated epithelial-mesenchymal signalling.	HOXD13 GLI1	5.91e-05	7	59	2	16908629
Pubmed	TrkB-dependent EphrinA reverse signaling regulates callosal axon fasciculate growth downstream of Neurod2/6.	SEMA3A SEMA6C SEMA6B	7.13e-05	47	59	3	35462405
Pubmed	Nr2f1 heterozygous knockout mice recapitulate neurological phenotypes of Bosch-Boonstra-Schaaf optic atrophy syndrome and show impaired hippocampal synaptic plasticity.	MYO7A MMP14	7.87e-05	8	59	2	31600777
Pubmed	A hypermorphic mouse Gli3 allele results in a polydactylous limb phenotype.	HOXD13 GLI1	7.87e-05	8	59	2	17266131
Pubmed	Genetic basis for an evolutionary shift from ancestral preaxial to postaxial limb polarity in non-urodele vertebrates.	HOXD13 GLI1	7.87e-05	8	59	2	34610275
Pubmed	FGF signalling through Fgfr2 isoform IIIb regulates adrenal cortex development.	GLI1 NR5A1	7.87e-05	8	59	2	23376610
Pubmed	Activation of the Hedgehog pathway in the mouse fetal ovary leads to ectopic appearance of fetal Leydig cells and female pseudohermaphroditism.	GLI1 NR5A1	7.87e-05	8	59	2	19268447
Pubmed	Patterning and post-patterning modes of evolutionary digit loss in mammals.	HOXD13 GLI1	7.87e-05	8	59	2	24990742
Pubmed	Unique functions of Sonic hedgehog signaling during external genitalia development.	HOXD13 GLI1	7.87e-05	8	59	2	11684660
Pubmed	Deterministic and stochastic allele specific gene expression in single mouse blastomeres.	LHX2 FOXD3 GLI1 PEX7 NR5A1 NOTCH3	8.27e-05	424	59	6	21731673
Pubmed	An extracellular biochemical screen reveals that FLRTs and Unc5s mediate neuronal subtype recognition in the retina.	SEMA3A SEMA6C SEMA6B	9.66e-05	52	59	3	26633812
Pubmed	Identification of disease-relevant modulators of the SHH pathway in the developing brain.	GLI1 LRP2	1.01e-04	9	59	2	34463328
Pubmed	Expression of the type IV collagenase system during mouse kidney development and tubule segmentation.	LRP2 MMP14	1.01e-04	9	59	2	11675412
Pubmed	Some distal limb structures develop in mice lacking Sonic hedgehog signaling.	HOXD13 GLI1	1.01e-04	9	59	2	11118883
Pubmed	Etv2 regulates enhancer chromatin status to initiate Shh expression in the limb bud.	HOXD13 GLI1	1.01e-04	9	59	2	35864091
Pubmed	The pleiotropic mouse phenotype extra-toes spotting is caused by translation initiation factor Eif3c mutations and is associated with disrupted sonic hedgehog signaling.	HOXD13 GLI1	1.01e-04	9	59	2	21292980
Pubmed	Plexin-a4 mediates axon-repulsive activities of both secreted and transmembrane semaphorins and plays roles in nerve fiber guidance.	SEMA3A SEMA6B	1.01e-04	9	59	2	15814794
Pubmed	Cholesterol modification restricts the spread of Shh gradient in the limb bud.	HOXD13 GLI1	1.01e-04	9	59	2	16611729
Pubmed	Mouse limbs expressing only the Gli3 repressor resemble those of Sonic hedgehog mutants.	HOXD13 GLI1	1.01e-04	9	59	2	23644062
Pubmed	Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.	PRR12 GLI1 BMS1 JMJD1C FAM83H ZNF503	1.25e-04	457	59	6	32344865
Pubmed	Progression of vertebrate limb development through SHH-mediated counteraction of GLI3.	HOXD13 GLI1	1.26e-04	10	59	2	12215652
Pubmed	Polydactyly in the mouse mutant Doublefoot involves altered Gli3 processing and is caused by a large deletion in cis to Indian hedgehog.	HOXD13 GLI1	1.26e-04	10	59	2	18272352
Pubmed	Developmental expression of Smoc1 and Smoc2 suggests potential roles in fetal gonad and reproductive tract differentiation.	GLI1 NR5A1	1.26e-04	10	59	2	19842175
Pubmed	Transcriptional Suppression by Transient Recruitment of ARIP4 to Sumoylated nuclear receptor Ad4BP/SF-1.	NR5A1 RAD54L2	1.26e-04	10	59	2	19692572
Pubmed	V1 spinal neurons regulate the speed of vertebrate locomotor outputs.	FOXD3 MNX1	1.26e-04	10	59	2	16525473
Pubmed	Cholesterol side-chain cleavage cytochrome P450 gene expression in the primitive gut of the mouse embryo does not require steroidogenic factor 1.	NR5A1 PGR	1.26e-04	10	59	2	7476982
Pubmed	Function and regulation of Alx4 in limb development: complex genetic interactions with Gli3 and Shh.	HOXD13 GLI1	1.26e-04	10	59	2	16039644
Pubmed	The Shh-independent activator function of the full-length Gli3 protein and its role in vertebrate limb digit patterning.	HOXD13 GLI1	1.26e-04	10	59	2	17400206
Pubmed	Novel role for the orphan nuclear receptor Dax1 in embryogenesis, different from steroidogenesis.	NR5A1 PGR	1.26e-04	10	59	2	16466956
Pubmed	Bapx1 homeobox gene gain-of-function mice show preaxial polydactyly and activated Shh signaling in the developing limb.	HOXD13 GLI1	1.26e-04	10	59	2	16791844
Pubmed	Evidence that preaxial polydactyly in the Doublefoot mutant is due to ectopic Indian Hedgehog signaling.	HOXD13 GLI1	1.54e-04	11	59	2	9671585
Pubmed	Sufu- and Spop-mediated regulation of Gli2 is essential for the control of mammalian cochlear hair cell differentiation.	MYO7A GLI1	1.54e-04	11	59	2	36252002
Pubmed	An Atoh1 CRE Knock-In Mouse Labels Motor Neurons Involved in Fine Motor Control.	MNX1 FIGN	1.54e-04	11	59	2	33468540
Pubmed	Ventral migration of early-born neurons requires Dcc and is essential for the projections of primary afferents in the spinal cord.	SEMA3A FOXD3	1.54e-04	11	59	2	15788454
Pubmed	Replicated anterior zeugopod (raz): a polydactylous mouse mutant with lowered Shh signaling in the limb bud.	HOXD13 GLI1	1.54e-04	11	59	2	14597572
Pubmed	Sonic hedgehog regulation of Foxf2 promotes cranial neural crest mesenchyme proliferation and is disrupted in cleft lip morphogenesis.	GLI1 FOXL1	1.54e-04	11	59	2	28506991
Pubmed	Shh and Gli3 are dispensable for limb skeleton formation but regulate digit number and identity.	HOXD13 GLI1	1.54e-04	11	59	2	12198547
Pubmed	Lbx1 and Tlx3 are opposing switches in determining GABAergic versus glutamatergic transmitter phenotypes.	SLC32A1 LHX2	1.85e-04	12	59	2	16234809
Pubmed	Follistatin regulates the specification of the apical cochlea responsible for low-frequency hearing in mammals.	MYO7A GLI1	1.85e-04	12	59	2	36577057
Pubmed	Cholesterol modification of sonic hedgehog is required for long-range signaling activity and effective modulation of signaling by Ptc1.	HOXD13 GLI1	1.85e-04	12	59	2	11389830
Pubmed	On and off retinal circuit assembly by divergent molecular mechanisms.	SEMA6C SEMA6B	1.85e-04	12	59	2	24179230
Pubmed	Mutanlallemand (mtl) and Belly Spot and Deafness (bsd) are two new mutations of Lmx1a causing severe cochlear and vestibular defects.	MYO7A FOXL1	1.85e-04	12	59	2	23226461
Interaction	ATN1 interactions	ZSWIM8 LRP2 RAD54L2 DMPK RBFOX2 ZNF503	1.76e-05	187	59	6	int:ATN1
Interaction	FEV interactions	PRR12 HOXC9 MNX1 DPF2 RAD54L2 ZNF503	2.80e-05	203	59	6	int:FEV
Interaction	FSAF1 interactions	BMS1 HECTD1 RBFOX2 WDTC1	2.86e-05	60	59	4	int:FSAF1
Interaction	PAX9 interactions	PRR12 MNX1 DPF2 FIGN ZNF503	3.92e-05	130	59	5	int:PAX9
Cytoband	3p21.2	RBM15B RAD54L2	2.74e-04	19	59	2	3p21.2
Cytoband	10q22.2	ZSWIM8 ZNF503	1.29e-03	41	59	2	10q22.2
GeneFamily	Immunoglobulin like domain containing\|Semaphorins	SEMA3A SEMA6C SEMA6B	1.29e-05	20	42	3	736
GeneFamily	HOXL subclass homeoboxes	HOXC9 MNX1 HOXD13	2.38e-04	52	42	3	518
GeneFamily	Forkhead boxes	FOXD3 FOXL1	4.48e-03	43	42	2	508
GeneFamily	Nuclear hormone receptors	NR5A1 PGR	5.78e-03	49	42	2	71
Coexpression	BENPORATH_EED_TARGETS	SLC32A1 LHX2 FOXD3 HOXC9 MNX1 HOXD13 VGLL2 LRP2 JMJD1C PGR ZNF503 FOXL1	3.44e-06	1059	59	12	M7617
Coexpression	BENPORATH_PRC2_TARGETS	SLC32A1 LHX2 FOXD3 MNX1 HOXD13 LRP2 PGR ZNF503 FOXL1	1.39e-05	650	59	9	M8448
Coexpression	BENPORATH_SUZ12_TARGETS	SLC32A1 LHX2 FOXD3 HOXC9 MNX1 HOXD13 LRP2 GRIN2D PGR ZNF503 FOXL1	1.70e-05	1035	59	11	M9898
Coexpression	BENPORATH_ES_WITH_H3K27ME3	SLC32A1 LHX2 FOXD3 MNX1 HOXD13 VGLL2 LRP2 GRIN2D PGR ZNF503 FOXL1	3.37e-05	1115	59	11	M10371
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-10w-Neuronal-Intermediate\|10w / Sample Type, Dataset, Time_group, and Cell type.	HPN RTN4RL1 ESPL1 JMJD1C RBFOX2 ZNF503 WDTC1	8.66e-09	200	59	7	e5a8647c47a49c8c90c78d681193946de103d8ff
ToppCell	droplet-Thymus-nan-3m-Myeloid-B_cell\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FCSK HPN TMEM102 ITGA2B DMPK	2.74e-06	166	59	5	c0af93db981dfd448abc7efcd257f3e5ff066aae
ToppCell	Cerebellum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)\|Cerebellum / BrainAtlas - Mouse McCarroll V32	SEMA6C SLC32A1 GRIN2D PGR FAM83H	2.82e-06	167	59	5	9efb9511a211d0824bb97f82c1a5860c43d2138f
ToppCell	Cerebellum-Neuronal-Inhibitory\|Cerebellum / BrainAtlas - Mouse McCarroll V32	SEMA6C SLC32A1 GRIN2D PGR FAM83H	2.82e-06	167	59	5	904c613aac3f9919a432b110bb1dcc832b5aec0a
ToppCell	10x3'2.3-week_17-19-Mesenchymal_osteo-stroma-osteoblast_precursor\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	LHX2 HOXC9 VGLL2 FIGN RBFOX2	6.01e-06	195	59	5	ec12cfb2fce44cc2de4e198ef5af075e626f0329
ToppCell	3'-GW_trimst-1-SmallIntestine-Mesenchymal-fibroblastic\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HS6ST1 MMP14 TCTN1 ZNF503 FOXL1	6.64e-06	199	59	5	30ab0750d51f168b18c434c974d24a4e70f29cc7
ToppCell	10x3'2.3-week_17-19-Mesenchymal_myocytic-stroma\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	SEMA3A HOXC9 VGLL2 NOTCH3 RBFOX2	6.64e-06	199	59	5	e19b296d583f8bad3b66ee998a8153634d6fe09e
ToppCell	10x3'2.3-week_17-19-Mesenchymal_myocytic\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	SEMA3A HOXC9 VGLL2 NOTCH3 RBFOX2	6.64e-06	199	59	5	801887db51ac5dc5b068808ff75e3a46643398e9
ToppCell	LPS-IL1RA-Endothelial-Epi-like-Gen_Cap\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LRP2 ZBTB3 PGR FAM83H	2.44e-05	127	59	4	6b24630978eb0772b4cd3bf59e5bc4390be47619
ToppCell	5'-Adult-Appendix-Hematopoietic-T_cells-ILC3\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MYO7A HPN NR5A1 ADAM10	6.47e-05	163	59	4	00e791358a7eb6c3e95f87afe22153845012e4a1
ToppCell	Frontal_cortex-Neuronal-Inhibitory\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	SEMA6C SLC32A1 GRIN2D GAA	7.44e-05	169	59	4	78eb70dd916724e476eabccf18fb7fcec4210308
ToppCell	PND14-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SEMA3A SEMA6B HPN ADAM10	7.79e-05	171	59	4	686f95892c3909973c66c9a27159a070a068f175
ToppCell	PND14-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SEMA3A SEMA6B HPN ADAM10	7.79e-05	171	59	4	f7ba03e7bdb687f93782c936c7b3374cc5b3b77c
ToppCell	facs-Heart-RA-18m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FCSK GRIN2D ZBTB3 NOTCH3	7.79e-05	171	59	4	b54d9d6b03c9c6f28a71cf2ed2bfa9a335bba949
ToppCell	facs-Heart-RA-18m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FCSK GRIN2D ZBTB3 NOTCH3	7.79e-05	171	59	4	9d825a2e799421af4f2cf4f4dc8e239b5d00476d
ToppCell	PND14-Endothelial-Endothelial_lymphatic\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SEMA3A SEMA6B HPN ADAM10	7.79e-05	171	59	4	d0ac50071a3854d02113c455fcc940a6ec59bbb9
ToppCell	PND14-Endothelial-Endothelial_lymphatic-Lymphatic_EC\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SEMA3A SEMA6B HPN ADAM10	7.79e-05	171	59	4	fbf8e9db00573adcada4b25730e191417b7c9999
ToppCell	5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SEMA3A HOXC9 MYO7A MPDZ	8.15e-05	173	59	4	7dc988fc0ba29990567bf1bcdeb3faeeee507eb1
ToppCell	Control-Myeloid-MoAM2,_CCL18\|Control / Condition, Lineage and Cell class	MYO7A HPX MMP14 ZNF503	8.33e-05	174	59	4	4c64ff5666812fb4efa440ba4faeca51d916d68e
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Mesenchymal-skeletal_muscle_satellite_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VGLL2 LRP2 DMPK NOTCH3	1.06e-04	185	59	4	5414a66169c39d09a67b1050aad5e61f46b3749a
ToppCell	10x3'2.3-week_12-13-Mesenchymal_adipo\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	SEMA3A HOXC9 HPX FIGN	1.10e-04	187	59	4	f1d0fc625e0e7881b3f290742fd7148d995eb71e
ToppCell	10x3'2.3-week_12-13-Mesenchymal_adipo-stroma\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	SEMA3A HOXC9 HPX FIGN	1.10e-04	187	59	4	02e7246ef5ad41773d14426254e139b156d45c1d
ToppCell	10x3'2.3-week_12-13-Mesenchymal_adipo-stroma-adipo-CAR\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	SEMA3A HOXC9 HPX FIGN	1.10e-04	187	59	4	08c73d125e0638c9e9878165bba2442c266c8a48
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	SLC32A1 GRIN2D GAA PGR	1.12e-04	188	59	4	b73e8a40393c3f656e2fcfe395a761b1f985c254
ToppCell	10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_neural-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SLC32A1 HOXC9 UBAP2 MNX1	1.15e-04	189	59	4	8e6b6025f5554672e26a5d19fe365acb4333789c
ToppCell	critical-Lymphoid-NK\|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	MPDZ FIGN MMP14 ZNF503	1.24e-04	193	59	4	6be11fef87af04ee7a3cc223882ccd4077caded9
ToppCell	10x3'2.3-week_17-19-Mesenchymal_myocytic-stroma-myofibroblast\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	SEMA3A HOXC9 VGLL2 RBFOX2	1.24e-04	193	59	4	02dfd1df1e7fc84bfca2b0c95138b5b4408bb5d1
ToppCell	wk_15-18-Epithelial-Proximal_epithelial-Proximal_secretory_1\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	FCSK CCDC71 TMC5 FIGN	1.24e-04	193	59	4	0ef076417ffe2dd1cbc2c3d1e35c7f8522af143b
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Epithelial-TECs\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LHX2 TMEM102 MMP14 RBFOX2	1.29e-04	195	59	4	17c4d3b59cd0d79ce9ae5dde95586f3e923db16f
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Stem_cells\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	SEMA3A LHX2 LRP2 FIGN	1.29e-04	195	59	4	2fa0216ba493d9722324c0a9a0c59c40e72b3c4e
ToppCell	10x5'v1-week_14-16-Mesenchymal_myocytic-stroma-myofibroblast\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	HOXC9 HHIPL2 RBFOX2 PGR	1.29e-04	195	59	4	30ed961151b8b1f6ce37f06c9a061519f01c2864
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Stem_cells-retina_progenitors\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	SEMA3A LHX2 LRP2 FIGN	1.29e-04	195	59	4	06a437459717dc3c41ec343b1ec57cf910ecbdd8
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Epithelial-epithelial_cell_of_thymus\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LHX2 TMEM102 MMP14 RBFOX2	1.29e-04	195	59	4	66caa5c063184e7d3d653c8f6c289555cb36fa82
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Epithelial\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LHX2 TMEM102 MMP14 RBFOX2	1.29e-04	195	59	4	ed74c113074fb5d3c42f2330b0e6042d32c3611a
ToppCell	10x3'2.3-week_14-16-Mesenchymal_osteo-stroma-osteochondral_precursor\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	HOXC9 MMP14 NOTCH3 RBFOX2	1.34e-04	197	59	4	c165c6fd12dc649b39e920d8528e2eb65c61956b
ToppCell	3'-GW_trimst-1-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(CH25H+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HS6ST1 MMP14 TCTN1 FOXL1	1.34e-04	197	59	4	467e7cbf511d3bcc701923603032aaf0bba2736d
ToppCell	10x3'2.3-week_17-19-Mesenchymal_myocytic-stroma-muscle_stem_cell\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	SEMA3A HOXC9 VGLL2 NOTCH3	1.37e-04	198	59	4	55e583321f60c95898d93cd0d2615c6692db52ec
ToppCell	10x3'2.3-week_14-16-Mesenchymal_osteo-stroma-osteoblast_precursor\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	SEMA3A HOXC9 NOTCH3 RBFOX2	1.37e-04	198	59	4	9d61483b0decac2fe90045b3474843360b2c49b3
ToppCell	Kidney\|World / Skin and Kidney Cells in Lupus Nephritis Patients.	PAPPA2 HPN LRP2 ZNF503	1.42e-04	200	59	4	1f99afa1f3c32a2a9cfb4ad33ff4d404e34fac63
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-5w-Neuronal-Interneuron\|5w / Sample Type, Dataset, Time_group, and Cell type.	SEMA3A SLC32A1 RBFOX2 ZNF503	1.42e-04	200	59	4	c7e33057466915d4e2b34f2062b22d9cdffa69dc
Disease	alcohol use disorder (implicated_via_orthology)	SLC32A1 CTBP1 DPF2 JMJD1C NOTCH3	4.13e-05	195	58	5	DOID:1574 (implicated_via_orthology)
Disease	Abnormality of vision	PRR12 FCSK	5.67e-05	6	58	2	C4025846
Disease	Intellectual Disability	PRR12 FCSK LRP2 DPF2 GRIN2D TCTN1	2.43e-04	447	58	6	C3714756
Disease	Amelogenesis imperfecta	ACP4 FAM83H	5.07e-04	17	58	2	cv:C0002452
Disease	Adenoid Cystic Carcinoma	ESPL1 JMJD1C RBFOX2	1.02e-03	100	58	3	C0010606
Disease	Malignant neoplasm of breast	SEMA3A GLI1 GRIN2D MMP14 ZBTB3 ADAM10 NOTCH3 PGR	1.14e-03	1074	58	8	C0006142
Disease	Kallmann Syndrome	SEMA3A HS6ST1	1.20e-03	26	58	2	C0162809
Disease	fibrinogen measurement	PRR12 JMJD1C NOTCH3	1.31e-03	109	58	3	EFO_0004623

Protein segments in the cluster

Peptide	Gene	Start	Entry
HPELNGAAYRYPPGV	CTBP1	371	Q13363
INYPHKYGPQGGCAD	ADAM10	161	O14672
VQPYEHGYPVSGGFA	RAD54L2	1281	Q9Y4B4
FDPHYPIILGGLGNS	BMS1	901	Q14692
GGFLAHAYFPGPNIG	MMP14	196	P50281
PAGVFGGLHSLQYLY	RTN4RL1	141	Q86UN2
PADPLGYLPLHGGYQ	RBM15B	246	Q8NDT2
HKYAPNPGGGSYSLQ	ARHGAP39	416	Q9C0H5
PYHALAPAASYGVGA	RBFOX2	361	O43251
LHAGLPSQEYAPGYN	FIGN	176	Q5HY92
AGGRHYALKPDAYPG	HOXC9	111	P31274
GLPAQAALYGHPVYG	MNX1	151	P50219
YPNGTHAYSGLGLPS	JMJD1C	866	Q15652
GRHGYAAEFSPYLPG	PEX7	16	O00628
YLAVPGHGEEYPAAG	NOTCH3	2211	Q9UM47
LGAAGANPLGLPYYN	LHX2	201	P50458
HSGLYPGPKALGGTY	GLI1	786	P08151
DNPRGLALHPQYGYL	LRP2	3321	P98164
GAPLGVHLPFVGYSY	DMPK	391	Q09013
ILYQYAGPGLSLGAP	HS6ST1	31	O60243
QLGVQAVVYHGGYLP	HPN	231	P05981
AVVYHGGYLPFRDPN	HPN	236	P05981
LYPALGLNGLPQLGY	PGR	511	P06401
QGALGLYDGHTPPYA	ACP4	296	Q9BZG2
HLGGIVLSPAYYGMP	PAPPA2	711	Q9BXP8
LPGSPAYAQNHGVYL	FCSK	176	Q8N0W3
GAAVGFPTHLYPGVY	CCDC71	156	Q8IV32
HVDLGGGLKPPGYYV	HECTD1	2206	Q9ULT8
LGAGPGAPLLYYVNQ	ESPL1	2081	Q14674
AAAPPSAPALGYGYH	HOXD13	116	P35453
TPGANLYGSHPFYLA	GAA	286	P10253
PHVQGGFYQLGIPFL	FOXL1	316	Q12952
AYALAPYAGAGPLVG	FAM83H	296	Q6ZRV2
EPGAHPAIYAYGIRN	HHIPL2	406	Q6UWX4
GNAKIYQLPGGHFYL	OLAH	226	Q9NV23
YQLPGGHFYLLDPAN	OLAH	231	Q9NV23
YGRPYGLHPAAAAGA	FOXD3	271	Q9UJU5
NGPGLYLIHGPNLYC	HPX	421	P02790
RLYLASHPQYAGPGA	SH2B1	46	Q9NRF2
MAVPGAHGPLAGYLY	NR5A1	171	Q13285
AHGPLAGYLYPAFPG	NR5A1	176	Q13285
VFLGPYAHRDGPNYQ	SEMA3A	351	Q14563
APGGYYFLGLLAQAP	ITGA2B	216	P08514
LYGVQGEPYPGPAAH	PRR12	506	Q9ULL5
LGHRAYAPGGPAYQP	COASY	391	Q13057
GSGIYAPNGPKVYHY	VNN2	276	O95498
YLNHYPVFVGSGPGR	SEMA6B	41	Q9H3T3
PLPDGAAQYYVAGHL	WDTC1	241	Q8N5D0
HNQYLVGPGGLLPAY	UBAP2	806	Q5T6F2
HPYALGGALGAQAAP	VGLL2	206	Q8N8G2
IVGGYGSPHGDLPIY	MPDZ	2001	O75970
GYVVGLPLAAGFQPH	TCTN1	381	Q2MV58
LGPYARGPHYDAGFT	TMEM102	106	Q8N9M5
HRGPGLASGQLYSYP	DPF2	61	Q92785
GPSRYSGGPGKHLLY	SEMA6C	871	Q9H3T2
GVHPAFLGAQYPYSV	ZSWIM8	1551	A7E2V4
AYAGYPPQFLPHGVA	ZNF503	366	Q96F45
NPAYVGESGPVHAYG	TMC5	321	Q6UXY8
GLPYAILHGGYLGLF	SLC32A1	136	Q9H598
LPYHLLPGAGQYHRG	ZBTB3	421	Q9H5J0
YLRNFIHGGPPGYAP	MYO7A	1211	Q13402
GLADGFHRYYGPIEP	GRIN2D	956	O15399
FHRYYGPIEPQGLGL	GRIN2D	961	O15399