Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyCellularComponentFAR/SIN/STRIPAK complex

STRIP2 STRIP1

6.50e-0517152GO:0090443
MousePhenoincreased urine pH

SLC26A7 NOS1

7.22e-0513142MP:0009349
MousePhenoabnormal bicarbonate level

SLC26A7 NOS1

1.26e-0417142MP:0031394
MousePhenoabnormal bicarbonate homeostasis

SLC26A7 NOS1

1.41e-0418142MP:0031393
MousePhenoabnormal nervous system regeneration

NOS1 PTPRS

1.93e-0421142MP:0004858
MousePhenoabnormal urine pH

SLC26A7 NOS1

2.76e-0425142MP:0009348
MousePhenoacidosis

SLC26A7 NOS1

3.47e-0428142MP:0003031
DomainDUF3402

STRIP2 STRIP1

6.88e-072162PF11882
DomainN1221

STRIP2 STRIP1

6.88e-072162PF07923
DomainDUF3402

STRIP2 STRIP1

6.88e-072162IPR021819
DomainDUF3402

STRIP2 STRIP1

6.88e-072162SM01293
DomainN1221

STRIP2 STRIP1

6.88e-072162SM01292
DomainN1221

STRIP2 STRIP1

6.88e-072162IPR012486
DomainPDZ

NOS1 PDLIM7

6.34e-03141162PF00595
DomainPDZ

NOS1 PDLIM7

6.96e-03148162SM00228
Domain-

NOS1 PDLIM7

7.14e-031501622.30.42.10
DomainPDZ

NOS1 PDLIM7

7.23e-03151162PS50106
DomainPDZ

NOS1 PDLIM7

7.33e-03152162IPR001478
Pubmed

Far3 and five interacting proteins prevent premature recovery from pheromone arrest in the budding yeast Saccharomyces cerevisiae.

STRIP2 STRIP1

1.98e-07216212588993
Pubmed

TORC2 signaling is antagonized by protein phosphatase 2A and the Far complex in Saccharomyces cerevisiae.

STRIP2 STRIP1

1.98e-07216222298706
Pubmed

The STRIPAK complex components FAM40A and FAM40B regulate endothelial cell contractility via ROCKs.

STRIP2 STRIP1

5.95e-07316230509168
Pubmed

The protein factor-arrest 11 (Far11) is essential for the toxicity of human caspase-10 in yeast and participates in the regulation of autophagy and the DNA damage signaling.

STRIP2 STRIP1

5.95e-07316222782902
Pubmed

STRIPAK components determine mode of cancer cell migration and metastasis.

STRIP2 STRIP1

2.97e-06616225531779
Pubmed

Identification and characterization of a set of conserved and new regulators of cytoskeletal organization, cell morphology and migration.

STRIP2 STRIP1

8.00e-052916221834987
Pubmed

A PP2A phosphatase high density interaction network identifies a novel striatin-interacting phosphatase and kinase complex linked to the cerebral cavernous malformation 3 (CCM3) protein.

STRIP2 STRIP1

2.03e-044616218782753
Pubmed

Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

FGB PTPRS TAS2R14

2.08e-0425716316335952
Pubmed

Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy.

FGB TERF1 PLCB4 GFRA3

2.26e-0468616429987050
InteractionRNF10 interactions

TERF1 PDLIM7 SETDB1 EED

5.67e-0787164int:RNF10
InteractionDYNLL2 interactions

NOS1 EED STRIP2 STRIP1

4.56e-05263164int:DYNLL2
InteractionPPP2CB interactions

TERF1 EED STRIP2 STRIP1

4.84e-05267164int:PPP2CB
InteractionGNL1 interactions

FGB SETDB1 EED

4.94e-0592163int:GNL1
InteractionPRDM14 interactions

EED STRIP2 STRIP1

5.44e-0595163int:PRDM14
InteractionBMP2K interactions

TERF1 PDLIM7 EED

7.33e-05105163int:BMP2K
CytobandEnsembl 112 genes in cytogenetic band chr8q21

TERF1 SLC26A7

2.01e-03192162chr8q21
GeneFamilyProtein phosphatase catalytic subunits|STRIPAK complex

STRIP2 STRIP1

1.05e-04201421371
GeneFamilyPDZ domain containing

NOS1 PDLIM7

5.98e-031521421220
ToppCellwk_15-18-Mesenchymal-Myofibro_&_SMC-MYL4+_SMC|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

TERF1 PDLIM7 GFRA3

4.44e-051971634797f414330316e2ac2cf7cd2570d991877d7a38
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L2/3_IT-L2/3_IT_ALM_Sla|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NOS1 STRIP2

9.98e-04132162ddebc0b233fdbb73ceb70187945bbed8fd273f2a
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FGB GFRA3

1.09e-03138162a88c3ae56b0af60f6e87cabade4f21e2bbb336f2
ToppCell10x5'-GI_small-bowel-Lymphocytic_Invariant-Inducer-like-MAIT|GI_small-bowel / Manually curated celltypes from each tissue

FGB STRIP2

1.22e-031461621cb2e157222631e8915d89b255a843d16d7d99cc
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_vein-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

NOS1 PLCB4

1.28e-031501624f31867cb85253ff6d22f3b02ef972a42cb41123
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_artery-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

NOS1 PLCB4

1.41e-03157162275a4c6fef1fff8da2bdc48e3924ad05c5e5cfc8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling-Cycling_Connecting_Tubule_Cell_low-phase|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC26A7 NLRP4

1.42e-03158162d72d6527dc50207ddbada262460d3c4bac249a19
ToppCellAdult-Mesenchymal-chondrocyte|Adult / Lineage, Cell type, age group and donor

PTPRS PDLIM7

1.44e-031591623f7305ee76447064b5c846c4f576360a2f7e0b7c
ToppCellsevere_COVID-19-pDC|World / disease group, cell group and cell class (v2)

PTPRS PLCB4

1.44e-03159162e1c48c4ceda116826819ff9adeed7bad6a58844d
ToppCellsevere_COVID-19-pDC|severe_COVID-19 / disease group, cell group and cell class (v2)

PTPRS PLCB4

1.44e-03159162ea5088d27e42b8850455764d53b757ea8d8f14bc
ToppCellNS-critical-d_16-33-Myeloid-Mast_cell|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

GFRA3 STRIP2

1.46e-03160162c61869d9dbba250270e59366e15af204e5b4395d
ToppCellAdult-Endothelial-endothelial_cell_of_vein-D122|Adult / Lineage, Cell type, age group and donor

NOS1 PLCB4

1.46e-031601620cfe130606af433b2aa90e0a20b6c44659dd6fd4
ToppCellAdult-Mesenchymal-airway_smooth_muscle_cell-D231|Adult / Lineage, Cell type, age group and donor

PDLIM7 PLCB4

1.46e-03160162d783d29150033e9181c0e30870070268fed3fd85
ToppCellAdult-Mesenchymal-airway_smooth_muscle_cell-D122|Adult / Lineage, Cell type, age group and donor

PDLIM7 PLCB4

1.48e-0316116264891f6f2ee1693c8481e951b9346e2f92d602e3
ToppCellChildren_(3_yrs)-Immune-dendritic_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

NOS1 NLRP4

1.48e-03161162cd41abb7ae659d3d314281783a0aaad562b26037
ToppCellnormal_Lung-Myeloid_cells-Undetermined|Myeloid_cells / Location, Cell class and cell subclass

PTPRS NLRP4

1.48e-03161162283012858e575c70d09950de53da041509f59bfa
ToppCell367C-Lymphocytic-CD4_T-cell-Treg_cell_3|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

PLCB4 TAS2R14

1.48e-0316116222fea192cd5f6d3544533d8b10e1d74dfedf0f05
ToppCellBronchial-NucSeq-Endothelial-Endothelia_vascular-VE_systemic_arterial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

NOS1 PLCB4

1.53e-031641623cd80e6275f0f9b5667912139d15ebf5e6b17f2f
ToppCellMild-Myeloid-Mast-|Mild / Condition, Lineage, Cell class and cell subclass

GFRA3 STRIP2

1.55e-0316516293d3909a0f5f43d473d5005c842d7d73e25eceed
ToppCellMild-Myeloid-Mast|Mild / Condition, Lineage, Cell class and cell subclass

GFRA3 STRIP2

1.55e-031651625fa9552c37890c5cc7e672a47038aebba2413cb4
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLC26A7 PTPRS

1.55e-031651624e13fccd32029e2879e85f8966e582a46c09e4aa
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_vein-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

NOS1 PLCB4

1.57e-03166162f7926ee266dcbf10df375cd921f1db5a2fa604f8
ToppCell10x5'-Liver-Myeloid_Dendritic-pDC|Liver / Manually curated celltypes from each tissue

PTPRS PLCB4

1.57e-0316616224dfa9f3e0842f9ab8350bf6a52ae0d10f2a0c44
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLC26A7 PTPRS

1.59e-03167162fe3338f99f94c0dac37e3d649dfdce82e4a56022
ToppCelldroplet-Liver-LIVER-NPC-1m-Myeloid-plasmacytoid_dendritic_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRS GFRA3

1.61e-03168162a007758c219d3d5db2b5529f29af63be0d408304
ToppCellAdult-Endothelial-endothelial_cell_of_artery-D231|Adult / Lineage, Cell type, age group and donor

NOS1 PLCB4

1.61e-03168162aca34c51758c65925ad24110294a72b2dea6db72
ToppCelldroplet-Liver-LIVER-NPC-1m-Myeloid-plasmacytoid_dendritic_cells|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRS GFRA3

1.61e-03168162e8878ec68b21c8d5694d7209b816d2f869673164
ToppCellAdult-Endothelial-endothelial_cell_of_artery-D122|Adult / Lineage, Cell type, age group and donor

NOS1 PLCB4

1.61e-031681628c3e1e45b422813bcdfa4273b1167db649a312f5
ToppCell10x5'-GI_small-bowel-Lymphocytic_Invariant-Inducer-like|GI_small-bowel / Manually curated celltypes from each tissue

FGB PLCB4

1.61e-03168162d02eba7ece17edcdd47fd6b784c93910ce61090f
ToppCellHealthy_Control-Lymphoid-pDC-|Healthy_Control / Condition, Lineage, Cell class and cell subclass

PTPRS NLRP4

1.63e-03169162338ce99897cb522b86edd603f75bc15ec4dfcda3
ToppCellHealthy_Control-Lymphoid-pDC|Healthy_Control / Condition, Lineage, Cell class and cell subclass

PTPRS NLRP4

1.63e-03169162a4e9b8b2f0338203455ba941b8f99bf4884d26f0
ToppCellAdult-Endothelial-endothelial_cell_of_vein-D175|Adult / Lineage, Cell type, age group and donor

NOS1 PLCB4

1.63e-03169162e1f0298236e4a1c59077c14f0dd29a78fac12648
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-mLTo|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC26A7 PLCB4

1.63e-03169162559e98216720e4babf0b0941100f1b485c35b11b
ToppCell10x5'-blood-Myeloid_Dendritic-pDC|blood / Manually curated celltypes from each tissue

PTPRS PLCB4

1.64e-0317016259cb1262ff319349d42b11afbec2a9035b7b79f2
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_artery-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

NOS1 PLCB4

1.66e-031711621597459c971d6befa991d59dc66b41b6a522f797
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs-Plasmacytoid_DCs_L.1.5.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PTPRS NLRP4

1.66e-031711624fd2c7977c512c51507f055fc74b111c0228ed8b
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-Plasmacytoid_Dendritic_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PTPRS NLRP4

1.66e-03171162af1c93eb75f45c042ea475d93db56e4da207e31f
ToppCellICU-SEP-Myeloid-pDC|ICU-SEP / Disease, Lineage and Cell Type

PTPRS PLCB4

1.66e-0317116272c448a0dc4c569bd6b465f9aa395f38034e7ea6
ToppCell3'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-D_cells_(SST+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC26A7 GFRA3

1.66e-03171162fa5cc720bd0045d0307439be547b41d56def5b43
ToppCellILEUM-inflamed-(4)_Mast|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

GFRA3 EXD3

1.68e-03172162be82f749f4b1049ae8832facc052082cf5463c11
ToppCellAdult-Mesenchymal-vascular_smooth_muscle_cell|Adult / Lineage, Cell type, age group and donor

PDLIM7 PLCB4

1.68e-03172162c62cad0f4212d1e9ea1ec3143ad3c4e06aff0ebf
ToppCellILEUM-inflamed-(4)_Mast_cells|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

GFRA3 EXD3

1.68e-031721627185b28282412f3a464b2a8ad5605475a1a31358
ToppCelldroplet-Spleen-SPLEEN-30m-Myeloid-macrophage_dendritic_cell_progenitor|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRS GFRA3

1.68e-0317216230916a902c151907745756d14327e24adc34afef
ToppCellmild_COVID-19-pDC|World / disease group, cell group and cell class (v2)

PTPRS PLCB4

1.68e-03172162dab2f1a05c7df58d9387b13271b3f1f1583f9ac3
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-ASMC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PDLIM7 PLCB4

1.70e-03173162cb6389536195443633adb06e5f1b7483530773d1
ToppCellAdult-Mesenchymal-airway_smooth_muscle_cell|Adult / Lineage, Cell type, age group and donor

PDLIM7 PLCB4

1.70e-03173162a5331721bd9f9a66530dd4ffe28cb3a5a8cad8fc
ToppCell5'-Adult-LargeIntestine-Epithelial-neuro-epithelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC26A7 GFRA3

1.72e-031741629f114e61458659005b6d0b4aa30a7a059e7aa5c6
ToppCellBAL-Control-Myeloid-pDC-pDC-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

PTPRS NLRP4

1.72e-03174162ab654e87c7eab7f33adc61be7a86da5c4d88008d
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_G2M|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TERF1 PDLIM7

1.72e-031741627fb7bdf62563f2102fb38618b503eb2817b6594f
ToppCellBAL-Control-Myeloid-pDC-pDC|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

PTPRS NLRP4

1.72e-031741622453419842fd22d066631615403393bfe4449bb8
ToppCell5'-Adult-LargeIntestine-Hematopoietic-Myeloid-Lymphoid_DC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC26A7 NOS1

1.72e-0317416216204ff504b7b382b4d90ca35003ad5336020e07
ToppCellAdult-Endothelial-endothelial_cell_of_vein-D231|Adult / Lineage, Cell type, age group and donor

NOS1 PLCB4

1.72e-031741622dd647c4fdf99fd1f7b838efef01baf2cbc3446d
ToppCellBAL-Control-Myeloid-pDC|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

PTPRS NLRP4

1.72e-03174162d9bccff5258c4277bdd1edbd87e17c327ec125e8
ToppCellHealthy_Control-Myeloid-Mast-|Healthy_Control / Condition, Lineage, Cell class and cell subclass

GFRA3 STRIP2

1.74e-03175162eadbbcdf2aef4cee268bc70a7a2c4175d898953b
ToppCell5'-Adult-LargeIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC26A7 GFRA3

1.74e-03175162182e45f5c02214d6b9f317ff5dc43af8b42de978
ToppCellnormal_Lymph_Node-B_lymphocytes-GrB-secreting_B_cells|normal_Lymph_Node / Location, Cell class and cell subclass

PTPRS PLCB4

1.74e-0317516229fbdfe1d3bfcb063be2bced0128a33176c5b78f
ToppCellmild_COVID-19-pDC|mild_COVID-19 / disease group, cell group and cell class (v2)

PTPRS PLCB4

1.74e-03175162b87f279a7519710146c49d6acccb0adedc195965
ToppCellAdult-Endothelial-endothelial_cell_of_artery-D175|Adult / Lineage, Cell type, age group and donor

NOS1 PLCB4

1.74e-031751620a65ddfa8c2e8efb5b5338cf07661cb78157a23c
ToppCellBAL-Control-Myeloid-pDC-pDC-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PTPRS NLRP4

1.74e-031751626839ee3bb4457d13cb08ca8eb79ae33ddd256783
ToppCelldroplet-Spleen-nan-3m-Myeloid-macrophage_dendritic_cell_progenitor|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRS GFRA3

1.74e-0317516221bc0e59a9509d38751ce6aad2325f341bc70eff
ToppCellBAL-Control-Myeloid-pDC|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PTPRS NLRP4

1.74e-031751626d5bdfbe53608e01c3845ecd908ca6d0fecc58f8
ToppCellBAL-Control-Myeloid-pDC-pDC|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PTPRS NLRP4

1.74e-031751629d6135e183179968555670abec39dff9da2c3219
ToppCellHealthy_Control-Myeloid-Mast|Healthy_Control / Condition, Lineage, Cell class and cell subclass

GFRA3 STRIP2

1.74e-03175162ca187074adcc9b8bd0fa270e2ede1564c8e6c6cf
ToppCellnormal_Lymph_Node-B_lymphocytes-GrB-secreting_B_cells|B_lymphocytes / Location, Cell class and cell subclass

PTPRS PLCB4

1.76e-03176162d6e660df92a3d7dd5732171ee623763faf108476
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-neuro-epithelial|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FGB SLC26A7

1.76e-03176162fb718a6b07aa5d56600263280afa530bcb63db42
ToppCellILEUM-inflamed-(3)_pDC|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

PTPRS NLRP4

1.76e-03176162b9f847dd55703e413f3cd815eef5724fffaf13b3
ToppCellAdult-Endothelial-endothelial_cell_of_vein|Adult / Lineage, Cell type, age group and donor

NOS1 PLCB4

1.76e-03176162043683c61c5d1a7f8a4666a612310246bd3d83a2
ToppCelldroplet-Lung-30m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PTPRS STRIP2

1.78e-031771624672cc75225a4a23b298afa8ce439628262519db
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_artery|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

NOS1 PLCB4

1.78e-031771625ff8dcfb030312126695d53a026d2e104a401b83
ToppCellPCW_05-06-Neuronal-Neuronal_SCP-neuro_pre_proliferating_SCP_(4)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

PLCB4 GFRA3

1.78e-0317716259726bfd98f656fdcedf448a7e2e76a9bfad8285
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Macroglial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FGB GFRA3

1.80e-03178162ef490b45901b2e6dedb519540fa3ae4e4db3a9ba
ToppCellmyeloid-Dendritic_cell-Plasmacytoid_dendritic_cell|myeloid / Lineage, cell class and subclass

PTPRS PLCB4

1.80e-03178162f75591988bbbeba073b66329a3437cb9b02f7648
ToppCellHealthy/Control-pDC|Healthy/Control / Disease group and Cell class

PTPRS PLCB4

1.80e-03178162072b346c6bbd63f00efaceda486400a669b3ec48
ToppCellEndothelial-A-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

SLC26A7 NOS1

1.80e-031781622f2602b9305d55f25afa9861dd6c6347ae179337
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Dendritic-plasmacytoid_dendritic_cell|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PTPRS PLCB4

1.82e-03179162124da6f882968dc0d05f3edd8f3b4d61617cc214
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Dendritic-plasmacytoid_dendritic_cell-DC_c4-LILRA4|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PTPRS PLCB4

1.82e-03179162edc5ef693dc4e7ea70717b77fb908fc784dce3a2
ToppCell3'-Adult-LargeIntestine-Epithelial-neuro-epithelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC26A7 GFRA3

1.82e-03179162f93e81a3fd94adedb24a9db4ac1d53e275bbf8b5
ToppCell10x3'2.3-week_14-16-Myeloid_neutrophil-granulo-eo/baso/mast-eosinophil|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

GFRA3 EXD3

1.82e-03179162810972561d1ae5a68389b54ceeac7a49890513a4
ToppCell3'_v3-bone_marrow-Mast|bone_marrow / Manually curated celltypes from each tissue

GFRA3 EXD3

1.84e-03180162b37ee81b792213d6595b4ec65d04bc35d83321c7
ToppCell3'-Distal_airway-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-Mast_cells_L.1.4.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GFRA3 EXD3

1.84e-031801628bd9e12589bff64987bac30af4d2514ba6f09300
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_vein-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

NOS1 PLCB4

1.84e-0318016227e8bbee388e64dd79d70b160b76d45b1f398006
ToppCell3'_v3-bone_marrow-Mast-Mast_cells|bone_marrow / Manually curated celltypes from each tissue

GFRA3 EXD3

1.86e-0318116230ec4635474ee0f0ea1415ec0ba7f008d97e8c1a
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-M/X_cells_(MLN/GHRL+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC26A7 GFRA3

1.86e-03181162cb17c904ab86d56dd30cac9b61acbb3b76f84ded
ToppCelldroplet-Marrow-BM-1m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRS GFRA3

1.86e-03181162fb64da1dde37fe6ba7de2586cd58848ac1974f24
ToppCellcritical-Myeloid-Mast_cell|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

GFRA3 EXD3

1.86e-03181162f0d81ae74d3f32979624a94b2ef93774831a7970
ToppCellHealthy/Control-pDC|World / Disease group and Cell class

PTPRS PLCB4

1.88e-0318216297e0eee10905f2cf2bebb09e474629fc224f4397
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TERF1 PDLIM7

1.88e-0318216237547b36264090b49a193a8ef3a8d88e647f0b79
ToppCellsystemic_lupus_erythematosus-treated-Myeloid-plasmacytoid_dendritic_cell-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

PTPRS PLCB4

1.88e-031821629bbe8062aa562dc3b9c299581faf6ebbcb72a9f7
ToppCell3'_v3-Lung-Myeloid_Dendritic-migDC|Lung / Manually curated celltypes from each tissue

NOS1 STRIP2

1.88e-03182162cd6e3a9f4eb4fe73b28da61d1d35c64fd9ffa892
ToppCellsystemic_lupus_erythematosus-treated-Myeloid-plasmacytoid_dendritic_cell|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

PTPRS PLCB4

1.88e-031821624602a98df7045e2c70b7560abfba9b444fbd5d30
ToppCell3'-GW_trimst-1.5-SmallIntestine-Epithelial-epithelial_progenitor_cell-TA|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FGB EXD3

1.90e-031831620d21befacefc6c597e7b501ed41b7fe9385a78df
ToppCell3'-Adult-LargeIntestine-Epithelial-neuro-epithelial-L_cells_(PYY+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC26A7 GFRA3

1.90e-0318316249f3ddc1c7c04b4ca837dbd6dad995add82941d6
ToppCellRA-13._Vascular_Smooth_Muscle|RA / Chamber and Cluster_Paper

PDLIM7 PLCB4

1.90e-03183162818fd886e0188091310825f9145fa53328f2c979
ToppCellAdult-Mesenchymal-pericyte_cell-D122|Adult / Lineage, Cell type, age group and donor

PDLIM7 PLCB4

1.90e-03183162fc31a43a637423cb3bb9aa184a3a889a0b9aaea6
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Dendritic-plasmacytoid_dendritic_cell|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PTPRS PLCB4

1.90e-03183162df6fd0927b6e4cf9a1583969a68096e4bccfbace
ToppCellControl-Endothelial_cells-Pulmonary_venous_endothelial_cells|Control / group, cell type (main and fine annotations)

NOS1 PLCB4

1.90e-0318316246be9f96755c7b65aeac061d95d15abeb6466034
ToppCelldroplet-Heart-4Chambers-21m-Neuronal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FGB GFRA3

1.90e-03183162a046b569bc10083d471b420eb2c6fee93437602d
Drugtrifluoperazine dihydrochloride; Down 200; 10uM; MCF7; HT_HG-U133A

NOS1 PTPRS PDLIM7 EXD3

8.41e-061931645584_DN
Drughaloperidol; Down 200; 10uM; PC3; HT_HG-U133A

NOS1 PTPRS PDLIM7 SETDB1

8.94e-061961644427_DN
DrugNaringenine [480-41-1]; Up 200; 14.6uM; HL60; HT_HG-U133A

PTPRS PDLIM7 EED

2.96e-041901631342_UP
DrugRapamycin; Down 200; 0.1uM; MCF7; HT_HG-U133A

PTPRS PDLIM7 EXD3

3.00e-041911635581_DN
DrugN6-methyladenosine [1867-73-8]; Up 200; 14.2uM; PC3; HT_HG-U133A

FGB PDLIM7 SETDB1

3.10e-041931636732_UP
DrugEstrone [53-16-7]; Down 200; 14.8uM; PC3; HT_HG-U133A

PTPRS PDLIM7 SETDB1

3.14e-041941636647_DN
Drug2-propylpentanoic acid; Down 200; 500uM; HL60; HT_HG-U133A

PTPRS PDLIM7 EXD3

3.14e-041941636199_DN
DrugSulfadimethoxine [122-11-2]; Down 200; 12.8uM; HL60; HT_HG-U133A

FGB NOS1 EXD3

3.19e-041951632578_DN
DrugBromopride [4093-35-0]; Down 200; 11.6uM; PC3; HT_HG-U133A

NOS1 PDLIM7 SETDB1

3.19e-041951633719_DN
Drug2-propylpentanoic acid; Down 200; 1000uM; MCF7; HT_HG-U133A

PTPRS PDLIM7 SETDB1

3.24e-041961635569_DN
DrugBetonicine [515-25-3]; Down 200; 25.2uM; HL60; HT_HG-U133A

NOS1 PDLIM7 EED

3.24e-041961632207_DN
DrugDequalinium dichloride [522-51-0]; Up 200; 7.6uM; MCF7; HT_HG-U133A

FGB NOS1 PTPRS

3.24e-041961632631_UP
DrugMethylprednisolone, 6-alpha [83-43-2]; Up 200; 10.6uM; PC3; HT_HG-U133A

PTPRS PDLIM7 SETDB1

3.24e-041961637137_UP
DrugApramycin [37321-09-8]; Up 200; 7.4uM; HL60; HT_HG-U133A

NOS1 PDLIM7 EXD3

3.24e-041961632914_UP
DrugSertaconazole nitrate [99592-39-9]; Up 200; 8uM; PC3; HT_HG-U133A

FGB NOS1 PDLIM7

3.29e-041971634475_UP
DrugTiaprofenic acid [33005-95-7]; Down 200; 15.4uM; PC3; HT_HG-U133A

PDLIM7 SETDB1 EED

3.29e-041971634091_DN
DrugCarisoprodol [78-44-4]; Up 200; 15.4uM; MCF7; HT_HG-U133A

FGB PDLIM7 EXD3

3.29e-041971634955_UP
DrugTelenzepine dihydrochloride [147416-96-4]; Up 200; 9uM; MCF7; HT_HG-U133A

PTPRS PDLIM7 EXD3

3.29e-041971637419_UP
DrugHeliotrine [303-33-3]; Down 200; 12.8uM; HL60; HT_HG-U133A

PTPRS PDLIM7 PLCB4

3.29e-041971632180_DN
DrugKhellin [82-02-0]; Down 200; 15.4uM; PC3; HT_HG-U133A

FGB NOS1 SETDB1

3.34e-041981636641_DN
DrugNitrendipine [39562-70-4]; Down 200; 11uM; HL60; HT_HG-U133A

PDLIM7 SETDB1 PLCB4

3.34e-041981633087_DN
DrugNaproxen [22204-53-1]; Up 200; 17.4uM; PC3; HT_HG-U133A

PDLIM7 SETDB1 EXD3

3.34e-041981636358_UP
DrugCaffeic acid [3331-39-5]; Down 200; 22.2uM; HL60; HT_HG-U133A

FGB NOS1 EXD3

3.34e-041981633053_DN
DrugTetramisole hydrochloride [16595-80-5]; Down 200; 16.6uM; HL60; HT_HG-U133A

PDLIM7 PLCB4 EXD3

3.34e-041981632489_DN
DrugSulfacetamide sodic hydrate [6209-17-2]; Up 200; 15.8uM; HL60; HT_HG-U133A

NOS1 PLCB4 EXD3

3.34e-041981631859_UP
Drugindomethacin, USP; Down 200; 100uM; PC3; HG-U133A

NOS1 SETDB1 TAS2R14

3.34e-04198163452_DN
DrugOxantel pamoate [68813-55-8]; Down 200; 6.6uM; PC3; HT_HG-U133A

NOS1 SETDB1 EED

3.34e-041981636738_DN
DrugIoversol [87771-40-2]; Down 200; 5uM; PC3; HT_HG-U133A

PDLIM7 EXD3 EED

3.34e-041981636726_DN
DrugCeforanide [60925-61-3]; Down 200; 7.6uM; HL60; HT_HG-U133A

PTPRS PDLIM7 PLCB4

3.34e-041981632447_DN
DrugNifurtimox [23256-30-6]; Down 200; 14uM; HL60; HT_HG-U133A

PLCB4 EXD3 EED

3.39e-041991632908_DN
DrugBuspirone hydrochloride [33386-08-2]; Down 200; 9.4uM; PC3; HT_HG-U133A

NOS1 EXD3 EED

3.39e-041991636743_DN
Drugestradiol, USP; Up 200; 0.1uM; MCF7; HT_HG-U133A

PTPRS PDLIM7 EXD3

3.39e-041991631633_UP
DrugDiazoxide [364-98-7]; Down 200; 17.4uM; MCF7; HT_HG-U133A

NOS1 PDLIM7 EXD3

3.39e-041991632214_DN
DrugLymecycline [992-21-2]; Up 200; 6.6uM; HL60; HT_HG-U133A

PTPRS PDLIM7 EXD3

3.39e-041991632953_UP
DrugErgocryptine-alpha [511-09-1]; Down 200; 7uM; HL60; HT_HG-U133A

FGB NOS1 PLCB4

3.39e-041991632572_DN
DrugAC1L1GEZ

SETDB1 PLCB4 EED

3.44e-04200163CID000003653
DrugCitalopram hydrobromide [59729-32-7]; Down 200; 1uM; MCF7; HT_HG-U133A

PTPRS PDLIM7 EXD3

3.44e-042001634377_DN
DrugThiamphenicol [15318-45-3]; Up 200; 11.2uM; MCF7; HT_HG-U133A

FGB SETDB1 EXD3

3.44e-042001631704_UP
Diseasetransient cerebral ischemia (implicated_via_orthology)

NOS1 EED

5.45e-0464162DOID:224 (implicated_via_orthology)
DiseaseParkinson Disease

FGB NOS1

9.59e-0485162C0030567
DiseaseSchizophrenia

SLC26A7 NOS1 SETDB1 GFRA3

1.09e-03883164C0036341
Diseasecoffee consumption measurement

SETDB1 TAS2R14

4.29e-03182162EFO_0006781
Diseasepost-traumatic stress disorder

TERF1 NOS1

5.25e-03202162EFO_0001358
Diseasemelanoma

SETDB1 PLCB4

7.81e-03248162C0025202

Protein segments in the cluster

PeptideGeneStartEntry
MKRMVSWSFHKLKTM

FGB

1

P02675
TLKNAEMKSAMRKLW

OR4A15

316

Q8NGL6
MDHSLKLWRINSKRM

EED

256

O75530
KTTLLMKLMMAWSDN

NLRP4

161

Q96MN2
KKITGEIMHALKMTW

PDLIM7

346

Q9NR12
AKKMNLDMRKTSSLW

NOS1

616

P29475
KVKMIMKTSVLLSWE

PTPRS

1041

Q13332
TSKPWKMNLSKLNML

GFRA3

141

O60609
LIFSMWKHRKKMQHT

TAS2R14

201

Q9NYV8
CLKKHWMKLAFMTNT

PLCB4

146

Q15147
LNKLTKWKHSRTMML

STRIP2

671

Q9ULQ0
KWKHSRTMMLVVFKS

STRIP2

676

Q9ULQ0
NKLTKWKHSRTMMLV

STRIP1

676

Q5VSL9
SMRILGKKRTKTWHK

SETDB1

201

Q15047
TSVMLKDRWRTMKKL

TERF1

416

P54274
RKKKSMLWSKMHTPQ

SLC26A7

6

Q8TE54
LLWVLTDSQLKAMMK

UHRF1BP1

241

Q6BDS2
LKVSRDMMKQLMWLS

EXD3

736

Q8N9H8