Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	metallopeptidase activity	CPB1 CPA5 ASTL NRDC MIPEP	6.47e-06	200	27	5	GO:0008237
GeneOntologyMolecularFunction	phospholipase activity	PLD2 PGAP6 PLA2G15	4.80e-04	114	27	3	GO:0004620
GeneOntologyMolecularFunction	metalloendopeptidase activity	ASTL NRDC MIPEP	5.57e-04	120	27	3	GO:0004222
GeneOntologyMolecularFunction	metallocarboxypeptidase activity	CPB1 CPA5	7.99e-04	31	27	2	GO:0004181
GeneOntologyMolecularFunction	lipase activity	PLD2 PGAP6 PLA2G15	8.37e-04	138	27	3	GO:0016298
GeneOntologyMolecularFunction	phospholipase A2 activity	PGAP6 PLA2G15	1.14e-03	37	27	2	GO:0004623
GeneOntologyMolecularFunction	peptidase activity	CPB1 CPA5 ASTL NRDC MIPEP	1.65e-03	654	27	5	GO:0008233
GeneOntologyMolecularFunction	carboxypeptidase activity	CPB1 CPA5	1.99e-03	49	27	2	GO:0004180
GeneOntologyMolecularFunction	metalloexopeptidase activity	CPB1 CPA5	4.02e-03	70	27	2	GO:0008235
GeneOntologyMolecularFunction	phospholipid binding	APBA1 PLD2 PLA2G15 AGAP6	5.96e-03	548	27	4	GO:0005543
Domain	-	CPB1 CPA5	5.61e-05	8	27	2	3.30.70.340
Domain	Propep_M14	CPB1 CPA5	5.61e-05	8	27	2	PF02244
Domain	M14A_act_pep	CPB1 CPA5	5.61e-05	8	27	2	IPR003146
Domain	Propept_inh	CPB1 CPA5	2.70e-04	17	27	2	IPR009020
Domain	Zn_pept	CPB1 CPA5	3.04e-04	18	27	2	SM00631
Domain	CARBOXYPEPT_ZN_2	CPB1 CPA5	3.39e-04	19	27	2	PS00133
Domain	CARBOXYPEPT_ZN_1	CPB1 CPA5	3.76e-04	20	27	2	PS00132
Domain	Peptidase_M14	CPB1 CPA5	5.00e-04	23	27	2	PF00246
Domain	Peptidase_M14	CPB1 CPA5	5.00e-04	23	27	2	IPR000834
Domain	MetalloPept_cat_dom	ASTL MIPEP	6.08e-03	81	27	2	IPR024079
Domain	-	ASTL MIPEP	6.08e-03	81	27	2	3.40.390.10
Domain	ZINC_PROTEASE	ASTL MIPEP	8.78e-03	98	27	2	PS00142
Pathway	KEGG_GLYCEROPHOSPHOLIPID_METABOLISM	PLD2 PLPP3 PLA2G15	1.21e-04	77	18	3	M9131
Pubmed	A transposon in Comt generates mRNA variants and causes widespread expression and behavioral differences among mice.	APBA1 STAU1	7.84e-05	17	27	2	20808911
Pubmed	RUNX1 maintains the identity of the fetal ovary through an interplay with FOXL2.	DMRT1 RYR2	1.21e-04	21	27	2	31712577
Pubmed	DNA sequence and analysis of human chromosome 9.	APBA1 ACTL7A CTNNAL1 DMRT1	1.82e-04	370	27	4	15164053
Pubmed	Expression of LPP3 in Bergmann glia is required for proper cerebellar sphingosine-1-phosphate metabolism/signaling and development.	PLD2 PLPP3	4.45e-04	40	27	2	21319224
Pubmed	Distinct class of putative "non-conserved" promoters in humans: comparative studies of alternative promoters of human and mouse genes.	DPY19L4 SNRNP200	6.67e-04	49	27	2	17567985
Cytoband	Ensembl 112 genes in cytogenetic band chr2q11	ASTL SNRNP200 REV1	1.00e-04	153	27	3	chr2q11
Cytoband	Ensembl 112 genes in cytogenetic band chr9q31	ACTL7A CTNNAL1	2.95e-03	137	27	2	chr9q31
Cytoband	Ensembl 112 genes in cytogenetic band chr1p32	NRDC PLPP3	3.76e-03	155	27	2	chr1p32
Cytoband	Ensembl 112 genes in cytogenetic band chr17p13	OR1A2 PLD2	1.76e-02	346	27	2	chr17p13
GeneFamily	Carboxypeptidases	CPB1 CPA5	2.41e-04	21	20	2	1321
GeneFamily	Phospholipases	PLD2 PLA2G15	9.75e-04	42	20	2	467
CoexpressionAtlas	FacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_2500_k-means-cluster#1	DPY19L4 OTX2 WDR54 STAU1 REV1	3.09e-05	306	26	5	Facebase_RNAseq_e10.5_Maxillary Arch_2500_K1
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_2500_k-means-cluster#5	DPY19L4 OTX2 WDR54 STAU1 REV1	5.85e-05	350	26	5	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_2500_K5
ToppCell	Bronchial-10x5prime-Epithelial-Epi_airway_neuro-secretory-Neuroendocrine\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	APBA1 CPB1 CPA5 RYR2	5.78e-06	197	27	4	3a0e97bfebe82f9687d518baaad7f20d0ffea8a1
Disease	exploratory eye movement measurement	SH3TC2 DMRT1	2.50e-03	81	27	2	EFO_0007700
Disease	Cardiac Hypertrophy	PLD2 PLPP3	2.56e-03	82	27	2	C1383860
Disease	Cardiomegaly	PLD2 PLPP3	2.56e-03	82	27	2	C0018800
Disease	Uterine leiomyoma	DMRT1 REV1	3.14e-03	91	27	2	HP_0000131
Disease	intelligence, self reported educational attainment	APBA1 STAU1	5.13e-03	117	27	2	EFO_0004337, EFO_0004784

Protein segments in the cluster

Peptide	Gene	Start	Entry
MLTPYDYSSVMHYGR	ASTL	226	Q6HA08
SNGMLTYYSSLGDYM	AGAP6	286	Q5VW22
AHSMGNMYTLYFLQR	PLA2G15	196	Q8NCC3
YGTTMGMYFRPLTSY	OR1A2	251	Q9Y585
SIHSYSQMLMYPYGR	CPA5	321	Q8WXQ8
SMMTSDNYYYTHSIW	PGAP6	711	Q9HCN3
YLMHNGNTVFSMYSY	C1QTNF3	181	Q9BXJ4
YGRNMSSMAYSLYLF	CTNNAL1	596	Q9UBT7
TSGMMYALYLSAYHE	DPY19L4	61	Q7Z388
MNAAYSGYVYTHRLF	APBA1	161	Q02410
YLAWYMTMSVLGHYN	RYR2	4721	Q92736
LTIHSYSQMMIYPYS	CPB1	301	P15086
RHAMSSQYRMHSYYP	DMRT1	281	Q9Y5R6
MQRSYPMTYTQASGY	OTX2	171	P32243
FSGHASFSMYTMLYL	PLPP3	196	O14495
RLATVYYSLHMYEMA	SH3TC2	1171	Q8TF17
MHIAYQSRLSMYSYG	ACTL7A	196	Q9Y615
CRIMSYSLYVNMYSS	CYSLTR2	111	Q9NS75
RYYSYLMSRAVASMV	MIPEP	631	Q99797
QSYYSLMHDVYGMLL	MRPS9	156	P82933
YSRMQSTYNYNMRGG	STAU1	96	O95793
MMLHGGQYHVYYSRS	REV1	71	Q9UBZ9
YYRMAAFGHHAYRMQ	SLC27A1	266	Q6PCB7
LREFWMRYYSSHYMT	NRDC	366	O43847
MRYYSSHYMTLVVQS	NRDC	371	O43847
AHNYTLYFMSDAYMG	SNRNP200	2101	O75643
NRLLTMSFYRNYHAM	PLD2	171	O14939
MYESNGYTMVYWHAL	WDR54	96	Q9H977