Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionH3K27me3 modified histone binding

CHD5 TAF1 TAF1L

2.05e-0651193GO:0061628
GeneOntologyMolecularFunctionalpha-1,3-mannosyltransferase activity

ALG8 ALG3

1.05e-0431192GO:0000033
GeneOntologyMolecularFunctionsynaptic receptor adaptor activity

SHANK1 SHANK3

2.10e-0441192GO:0030160
GeneOntologyMolecularFunctionsignaling receptor complex adaptor activity

SHANK1 SH2B3 SPATA2 SHANK3

3.01e-04541194GO:0030159
GeneOntologyMolecularFunctioncarbohydrate derivative transmembrane transporter activity

ABCC3 SLC29A3 SLC35D1 SLC35E3

4.24e-04591194GO:1901505
GeneOntologyMolecularFunctionacyltransferase activity, transferring groups other than amino-acyl groups

PNPLA2 ZDHHC8 ZDHHC20 BRCA2 NAT10 TAF1 TAF1L

5.65e-042381197GO:0016747
DomainTFIID_sub1_DUF3591

TAF1 TAF1L

4.03e-0521192IPR022591
DomainTBP-binding

TAF1 TAF1L

4.03e-0521192PF09247
DomainNCKAP5_C

NCKAP5 NCKAP5L

4.03e-0521192IPR032769
DomainDUF3591

TAF1 TAF1L

4.03e-0521192PF12157
DomainNckap5l

NCKAP5 NCKAP5L

4.03e-0521192IPR026163
DomainNCKAP5

NCKAP5 NCKAP5L

4.03e-0521192PF15246
DomainTAF_II_230-bd

TAF1 TAF1L

4.03e-0521192IPR009067
Domain-

TAF1 TAF1L

4.03e-05211921.10.1100.10
DomainTAF1_animal

TAF1 TAF1L

4.03e-0521192IPR011177
DomainSH3_2

SHANK1 SASH1 SHANK3 SH3PXD2B MYO15A

2.23e-04861195PF07653
DomainSH3_2

SHANK1 SASH1 SHANK3 SH3PXD2B MYO15A

2.23e-04861195IPR011511
DomainFERM_f0

SHANK1 SHANK3

2.40e-0441192PF16511
DomainFERM_f0

SHANK1 SHANK3

2.40e-0441192IPR032425
DomainSugar_P_trans_dom

SLC35D1 SLC35E3

1.75e-03101192IPR004853
DomainTPT

SLC35D1 SLC35E3

1.75e-03101192PF03151
Domain-

GLT6D1 UGGT1 EXTL3 EIF2B5

1.79e-038111943.90.550.10
DomainSAM

SHANK1 SASH1 SHANK3 ARAP3

2.42e-03881194SM00454
DomainNucleotide-diphossugar_trans

GLT6D1 UGGT1 EXTL3 EIF2B5

2.42e-03881194IPR029044
DomainOxysterol-bd_CS

OSBPL6 OSBP2

2.55e-03121192IPR018494
DomainOxysterol_BP

OSBPL6 OSBP2

2.55e-03121192PF01237
DomainOxysterol-bd

OSBPL6 OSBP2

2.55e-03121192IPR000648
DomainOSBP

OSBPL6 OSBP2

2.55e-03121192PS01013
DomainSAM_DOMAIN

SHANK1 SASH1 SHANK3 ARAP3

3.19e-03951194PS50105
DomainSAM

SHANK1 SASH1 SHANK3 ARAP3

3.44e-03971194IPR001660
Domain-

SHANK1 SASH1 SHANK3 ARAP3

4.72e-0310611941.10.150.50
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

ABCC3 PNPLA2 SH2B3 HECTD4 EXTL3 MED13L ZDHHC8 FANCA CCDC142 STK10 SLC7A1 SH3PXD2B ARAP3 PI4KA CHD5 NAV1 ZER1 GCN1

1.05e-0711051261835748872
Pubmed

Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.

TNIK DLGAP2 ASXL1 SASH1 NCKAP5 EXTL3 SHANK3 FANCA BRCA2 RPL13

3.66e-073291261017474147
Pubmed

A human MAP kinase interactome.

SHANK1 LAMA4 NCKAP5 SYNPO EXTL3 NCKAP5L SLC9A1 NAV1 PAK3 TAF1 GCN1

1.70e-064861261120936779
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

SHANK1 TNIK DLGAP2 WDR7 HECTD4 SYNPO TRIP11 SHANK3 SH3PXD2B PI4KA NAT10 NT5C2 NAV1 PAK3 CDH2

2.28e-069631261528671696
Pubmed

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.

TNIK ABCC3 NECTIN3 ZDHHC8 MTMR10 STK10 ZDHHC20 SLC7A1 SLC9A1 PI4KA NAV1

7.61e-065691261130639242
Pubmed

Alterations in the balance of tubulin glycylation and glutamylation in photoreceptors leads to retinal degeneration.

TTLL3 AGTPBP1

1.30e-052126228104815
Pubmed

Developmental impaired Akt signaling in the Shank1 and Shank3 double knock-out mice.

SHANK1 SHANK3

1.30e-052126233402706
Pubmed

Genetic variants in fanconi anemia pathway genes BRCA2 and FANCA predict melanoma survival.

FANCA BRCA2

1.30e-052126225243787
Pubmed

Taf1 knockout is lethal in embryonic male mice and heterozygous females show weight and movement disorders.

TAF1 TAF1L

1.30e-052126238804708
Pubmed

TAFII250, Egr-1, and D-type cyclin expression in mice and neonatal rat cardiomyocytes treated with doxorubicin.

TAF1 TAF1L

1.30e-052126210070062
Pubmed

Sustained expression of a neuron-specific isoform of the Taf1 gene in development stages and aging in mice.

TAF1 TAF1L

1.30e-052126222842574
Pubmed

Frameshift Mutations in the Mononucleotide Repeats of TAF1 and TAF1L Genes in Gastric and Colorectal Cancers with Regional Heterogeneity.

TAF1 TAF1L

1.30e-052126227571988
Pubmed

Striatal Cholinergic Dysregulation after Neonatal Decrease in X-Linked Dystonia Parkinsonism-Related TAF1 Isoforms.

TAF1 TAF1L

1.30e-052126234403156
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

TNIK ASXL1 MED13L ARHGEF15 CHD5 HPS5 GCN1

1.90e-05225126712168954
Pubmed

Elucidation of the Fanconi Anemia Protein Network in Meiosis and Its Function in the Regulation of Histone Modifications.

FANCA BRCA2 MDC1

2.51e-0516126327760317
Pubmed

The Shank family of scaffold proteins.

SHANK1 SHANK3

3.90e-053126210806096
Pubmed

Zinc deficiency and low enterocyte zinc transporter expression in human patients with autism related mutations in SHANK3.

SLC39A2 SHANK3

3.90e-053126228345660
Pubmed

The FANC/BRCA Pathway Releases Replication Blockades by Eliminating DNA Interstrand Cross-Links.

FANCA BRCA2

3.90e-053126232466131
Pubmed

USP8 Deubiquitinates SHANK3 to Control Synapse Density and SHANK3 Activity-Dependent Protein Levels.

SHANK1 SHANK3

3.90e-053126229735556
Pubmed

Regulated expression of TAF1 in 1-cell mouse embryos.

TAF1 TAF1L

3.90e-053126216822332
Pubmed

Synaptic scaffolding proteins in rat brain. Ankyrin repeats of the multidomain Shank protein family interact with the cytoskeletal protein alpha-fodrin.

SHANK1 SHANK3

3.90e-053126211509555
Pubmed

Translational neurobiology in Shank mutant mice--model systems for neuropsychiatric disorders.

SHANK1 SHANK3

3.90e-053126225917711
Pubmed

The Fanconi Anemia Pathway Protects Genome Integrity from R-loops.

FANCA BRCA2

3.90e-053126226584049
Pubmed

Modeling autism by SHANK gene mutations in mice.

SHANK1 SHANK3

3.90e-053126223583105
Pubmed

Changes in protein expression due to deleterious mutations in the FA/BRCA pathway.

BRCA2 MDC1

3.90e-053126217977515
Pubmed

TAFII55 binding to TAFII250 inhibits its acetyltransferase activity.

TAF1 TAF1L

3.90e-053126211592977
Pubmed

TLR7/8 stress response drives histiocytosis in SLC29A3 disorders.

SLC29A3 TLR8

3.90e-053126237462944
Pubmed

Functional substitution for TAF(II)250 by a retroposed homolog that is expressed in human spermatogenesis.

TAF1 TAF1L

3.90e-053126212217962
Pubmed

TAF7: a possible transcription initiation check-point regulator.

TAF1 TAF1L

3.90e-053126216407123
Pubmed

Reduction in parvalbumin expression not loss of the parvalbumin-expressing GABA interneuron subpopulation in genetic parvalbumin and shank mouse models of autism.

SHANK1 SHANK3

3.90e-053126226819149
Pubmed

Dynamic Change of Shanks Gene mRNA Expression and DNA Methylation in Epileptic Rat Model and Human Patients.

SHANK1 SHANK3

3.90e-053126232564287
Pubmed

Akirin2 is essential for the formation of the cerebral cortex.

AKIRIN2 DMRT3 CDH2

4.31e-0519126327871306
Pubmed

ER-export and ARFRP1/AP-1-dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication.

BICD2 SFXN4 WDR7 UGGT1 NECTIN3 TRIP11 ZDHHC20 SLC7A1 SLC9A1 TOMM40 SDC2 MFSD10 RPL13

4.41e-059521261338569033
Pubmed

Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma.

TNIK SASH1 NECTIN3 ZDHHC8 MTMR10 STK10 ZDHHC20 SLC9A1

7.31e-05377126838117590
Pubmed

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.

SHANK1 TNIK DLGAP2 WDR7 SYNPO SHANK3 PI4KA

7.76e-05281126728706196
Pubmed

SHANK3 gene mutations associated with autism facilitate ligand binding to the Shank3 ankyrin repeat region.

SHANK1 SHANK3

7.78e-054126223897824
Pubmed

Cutting edge: IL-21 and TLR signaling regulate germinal center responses in a B cell-intrinsic manner.

TLR8 IL21R

7.78e-054126220368279
Pubmed

Hematopoietic dysfunction in a mouse model for Fanconi anemia group D1.

FANCA BRCA2

7.78e-054126216859999
Pubmed

Role of nectin in formation of E-cadherin-based adherens junctions in keratinocytes: analysis with the N-cadherin dominant negative mutant.

NECTIN3 CDH2

7.78e-054126212686612
Pubmed

S-acylation controls SARS-CoV-2 membrane lipid organization and enhances infectivity.

ZDHHC8 ZDHHC20

7.78e-054126234599882
Pubmed

Congenital disorders of glycosylation: a booming chapter of pediatrics.

ALG8 ALG3

7.78e-054126215273506
Pubmed

The Shank family of postsynaptic density proteins interacts with and promotes synaptic accumulation of the beta PIX guanine nucleotide exchange factor for Rac1 and Cdc42.

SHANK1 SHANK3

7.78e-054126212626503
Pubmed

Congenital disorders of glycosylation (CDG): update and new developments.

ALG8 ALG3

7.78e-054126215272470
Pubmed

HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.

WDR7 TRIP11 ARHGEF15 CLPB BRCA2 PI4KA MDC1 NAT10 INPP5J RPL13 MAP3K19

9.83e-057541261135906200
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

TNIK BICD2 ASXL1 WDR7 MED13L SPATA2 NAV1 AGTPBP1

1.24e-04407126812693553
Pubmed

Direct interaction of post-synaptic density-95/Dlg/ZO-1 domain-containing synaptic molecule Shank3 with GluR1 alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor.

SHANK1 SHANK3

1.29e-045126216606358
Pubmed

BRCA-deficient metastatic prostate cancer has an adverse prognosis and distinct genomic phenotype.

FANCA BRCA2

1.29e-045126237549632
Pubmed

The insulin receptor substrate IRSp53 links postsynaptic shank1 to the small G-protein cdc42.

SHANK1 SHANK3

1.29e-045126212504591
Pubmed

MDC1 and RNF8 function in a pathway that directs BRCA1-dependent localization of PALB2 required for homologous recombination.

BRCA2 MDC1

1.29e-045126223038782
Pubmed

Tetratricopeptide-motif-mediated interaction of FANCG with recombination proteins XRCC3 and BRCA2.

FANCA BRCA2

1.29e-045126216621732
Pubmed

The insulin receptor substrate of 53 kDa (IRSp53) limits hippocampal synaptic plasticity.

SHANK1 SYNPO SHANK3

1.58e-0429126319208628
Pubmed

FANCA and FANCC modulate TLR and p38 MAPK-dependent expression of IL-1β in macrophages.

TLR8 FANCA

1.93e-046126224046015
Pubmed

FANCG promotes formation of a newly identified protein complex containing BRCA2, FANCD2 and XRCC3.

FANCA BRCA2

1.93e-046126218212739
Pubmed

Several tetratricopeptide repeat (TPR) motifs of FANCG are required for assembly of the BRCA2/D1-D2-G-X3 complex, FANCD2 monoubiquitylation and phleomycin resistance.

FANCA BRCA2

1.93e-046126220450923
Pubmed

Human Bex2 interacts with LMO2 and regulates the transcriptional activity of a novel DNA-binding complex.

NHLH2 TAF1

1.93e-046126216314316
Pubmed

Transforming growth factor-beta regulates basal transcriptional regulatory machinery to control cell proliferation and differentiation in cranial neural crest-derived osteoprogenitor cells.

TAF1 TAF1L

1.93e-046126219959467
Pubmed

Essential roles for the splicing regulator nSR100/SRRM4 during nervous system development.

SHANK1 TAF1 TAF1L

1.94e-0431126325838543
Pubmed

Polymorphic variants in hereditary pancreatic cancer genes are not associated with pancreatic cancer risk.

FANCA BRCA2 MDC1

1.94e-0431126319690177
Pubmed

A GSK3-binding peptide from FRAT1 selectively inhibits the GSK3-catalysed phosphorylation of axin and beta-catenin.

FRAT1 EIF2B5

2.70e-047126210481074
Pubmed

Direct interaction of GluRdelta2 with Shank scaffold proteins in cerebellar Purkinje cells.

SHANK1 SHANK3

2.70e-047126215207857
Pubmed

Genome-wide scan of copy number variation in late-onset Alzheimer's disease.

SASH1 TOMM40

2.70e-047126220061627
Pubmed

Proline-rich synapse-associated proteins ProSAP1 and ProSAP2 interact with synaptic proteins of the SAPAP/GKAP family.

DLGAP2 SHANK3

2.70e-047126210527873
Pubmed

A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.

ABCC3 WDR7 NECTIN3 FANCA STK10 SLC9A1 NAV1 ALG8 ALG3 CDH2

3.00e-047191261035337019
Pubmed

Conservation of position and exclusive expression of mouse Xist from the inactive X chromosome.

TAF1 TAF1L

3.59e-04812622034279
Pubmed

The G protein-coupled receptor CL1 interacts directly with proteins of the Shank family.

SHANK1 SHANK3

3.59e-048126210958799
Pubmed

Fragile X mental retardation protein regulates the levels of scaffold proteins and glutamate receptors in postsynaptic densities.

SHANK1 DLGAP2

3.59e-048126219640847
Pubmed

Physical mapping of 2000 kb of the mouse X chromosome in the vicinity of the Xist locus.

TAF1 TAF1L

3.59e-04812628468051
Pubmed

Proteomic and genomic evidence implicates the postsynaptic density in schizophrenia.

SYNPO SHANK3

3.59e-048126225048004
Pubmed

Genetic mapping in the region of the mouse X-inactivation center.

TAF1 TAF1L

3.59e-04812621974879
Pubmed

Deletion of Prl7d1 causes placental defects at mid-pregnancy in mice.

TAF1 TAF1L

3.59e-048126231012985
Pubmed

Sex Hormones Regulate SHANK Expression.

SHANK1 SHANK3

3.59e-048126230319350
Pubmed

High-density molecular map of the central span of the mouse X chromosome.

TAF1 TAF1L

3.59e-04812621675191
Pubmed

Cajal-Retzius cells instruct neuronal migration by coincidence signaling between secreted and contact-dependent guidance cues.

NECTIN3 CDH2

4.61e-049126223931996
Pubmed

The intracellular localisation of TAF7L, a paralogue of transcription factor TFIID subunit TAF7, is developmentally regulated during male germ-cell differentiation.

TAF1 TAF1L

4.61e-049126212665565
Pubmed

Conserved overlapping gene arrangement, restricted expression, and biochemical activities of DNA polymerase ν (POLN).

FANCA BRCA2

4.61e-049126226269593
Pubmed

Cloning and characterization of a new human Xq13 gene, encoding a putative helicase.

TAF1 TAF1L

4.61e-04912627874112
Pubmed

HIV-1 tat binds TAFII250 and represses TAFII250-dependent transcription of major histocompatibility class I genes.

TAF1 TAF1L

4.61e-04912629751712
Pubmed

FBXL13 directs the proteolysis of CEP192 to regulate centrosome homeostasis and cell migration.

CLPB BRCA2 AGTPBP1

4.81e-0442126329348145
Pubmed

Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

SYNPO MED13L ZFHX2 AGTPBP1

5.71e-04104126410470851
Pubmed

Contacts between the commissural axons and the floor plate cells are mediated by nectins.

NECTIN3 CDH2

5.75e-0410126215328010
Pubmed

Genetic and molecular evidence of an X-chromosome deletion spanning the tabby (Ta) and testicular feminization (Tfm) loci in the mouse.

TAF1 TAF1L

5.75e-041012622055107
Pubmed

Large-scale structural analysis of the classical human protein tyrosine phosphatome.

PTPRO CDH2 ALK

6.70e-0447126319167335
Pubmed

Characterization of a murine gene expressed from the inactive X chromosome.

TAF1 TAF1L

7.01e-041112622034278
Pubmed

Anuria, omphalocele, and perinatal lethality in mice lacking the CD34-related protein podocalyxin.

SYNPO PTPRO

7.01e-0411126211435469
Pubmed

SHANK proteins limit integrin activation by directly interacting with Rap1 and R-Ras.

SHANK1 SHANK3

7.01e-0411126228263956
Pubmed

The OSBP-related protein family in humans.

OSBPL6 OSBP2

7.01e-0411126211483621
Pubmed

Behavioral phenotypes of genetic mouse models of autism.

SHANK1 SHANK3

7.01e-0411126226403076
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

SASH1 FLYWCH1 HECTD4 SYNPO CHD5 MDC1 NAT10 HPS5

7.12e-04529126814621295
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

SHANK1 BICD2 HECTD4 NCKAP5 SYNPO EXTL3 MED13L TRIP11 MTMR10 CLPB TAF1 AGTPBP1 RPL13

8.08e-0412851261335914814
Pubmed

A family of 12 human genes containing oxysterol-binding domains.

OSBPL6 OSBP2

8.39e-0412126211735225
Pubmed

Synergistic action of nectins and cadherins generates the mosaic cellular pattern of the olfactory epithelium.

NECTIN3 CDH2

8.39e-0412126226929452
Pubmed

An oxysterol-binding protein family identified in the mouse.

OSBPL6 OSBP2

8.39e-0412126212215260
Pubmed

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.

TNIK SASH1 TRIP11 STK10 ZDHHC20 PI4KA CDH2

8.90e-04421126736976175
Pubmed

Mapping of loci and translocation breakpoints in Xq13: isolation of a conserved locus that maps close to CCG1 in human and mouse.

TAF1 TAF1L

9.89e-041312628012115
Pubmed

Requirement of tissue-selective TBP-associated factor TAFII105 in ovarian development.

TAF1 TAF1L

9.89e-0413126211557891
Pubmed

Rps4 maps near the inactivation center on the mouse X chromosome.

TAF1 TAF1L

9.89e-041312621740345
Pubmed

The Ubiquitin E3/E4 Ligase UBE4A Adjusts Protein Ubiquitylation and Accumulation at Sites of DNA Damage, Facilitating Double-Strand Break Repair.

BRCA2 MDC1

9.89e-0413126229499138
Pubmed

XIST and the mapping of the X chromosome inactivation centre.

TAF1 TAF1L

9.89e-041312621772416
Pubmed

Glutamatergic Dysfunction and Synaptic Ultrastructural Alterations in Schizophrenia and Autism Spectrum Disorder: Evidence from Human and Rodent Studies.

SHANK1 SHANK3

9.89e-0413126233374598
Pubmed

The murine interleukin-2 receptor gamma chain gene: organization, chromosomal localization and expression in the adult thymus.

TAF1 TAF1L

9.89e-041312627805729
GeneFamilySterile alpha motif domain containing

SHANK1 SASH1 SHANK3 ARAP3

4.65e-0488744760
GeneFamilyOxysterol binding proteins|Pleckstrin homology domain containing

OSBPL6 OSBP2

1.06e-0312742670
GeneFamilySolute carriers

SLC29A3 SLC39A2 SLC18B1 SLC35D1 SLC7A1 SLC9A1 SLC35E3

1.15e-03395747752
CoexpressionGSE2585_CTEC_VS_THYMIC_MACROPHAGE_DN

SLC29A3 UGGT1 HS1BP3 SLC18B1 AHRR BRCA2 PI4KA ALG3

5.28e-061991258M6264
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

DLGAP2 SASH1 LAMA4 SHANK3 SLC7A1 HMCN1 OSBP2

1.18e-0619012676e6ce6dd549d1c38cfef5b3f8be06ab01ce344b7
ToppCellControl-Endothelial-Endothelial-Gen_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SASH1 NCKAP5 SHANK3 ARHGEF15 ARAP3 HMCN1 NAV1

1.32e-061931267e1d546165dcc2392f540162206852c4717d7306f
ToppCellBronchial-NucSeq-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DLGAP2 SASH1 LAMA4 SHANK3 ZNF385D ARAP3 OSBP2

1.56e-061981267b3a020522e064bb61949d38e442f24026e339364
ToppCellBronchial-NucSeq-Endothelial-Endothelia_lymphatic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DLGAP2 SASH1 LAMA4 SHANK3 ZNF385D ARAP3 OSBP2

1.56e-061981267fc4b7c3ad52bc5c8b40fa04a156bfbb58afa2872
ToppCell368C-Lymphocytic-CD4_T-cell-CD4+_Naive_T_cell_/_CD4+_Trm_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

DRICH1 CHST6 FAAH2 ZNF295-AS1 C16orf46 PAK3

4.75e-061521266ca23261d8ef263cc697b8d7e7cb2afec8bc564f2
ToppCell368C-Lymphocytic-CD4_T-cell-CD4+_Naive_T_cell_/_CD4+_Trm_cell|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

DRICH1 CHST6 FAAH2 ZNF295-AS1 C16orf46 PAK3

6.38e-06160126619105debef96ea0c267d6a1d332303ec668ae47e
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SHANK3 ARHGEF15 AHRR ARAP3 NAV1 INPP5J

8.72e-061691266c7fc3a8c44f07c557b60d469717b66e2f5863d38
ToppCellLeuk-UTI-Myeloid-cDC1|Leuk-UTI / Disease, Lineage and Cell Type

NCKAP5 OSBPL6 NAV1 HPS5 CDH2 SDC2

9.96e-061731266226bb8d881f32d65c60f5e4c034c6d465f8e7ba5
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Neuronal-Neuron|GW19 / Sample Type, Dataset, Time_group, and Cell type.

TECRL STK10 SLC7A1 ARAP3 OSBPL6 SDC2

1.06e-0517512662812ac2ef41d245db544697fb6da1883361c96e8
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

WDR7 HECTD4 EXTL3 ZDHHC8 MYMK HPS5

1.06e-0517512661d8aab491dcc27ea5dbfb6462d18ee280b21a05e
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

WDR7 HECTD4 EXTL3 ZDHHC8 MYMK HPS5

1.06e-051751266427a7ee92fe16a90625946492062d37aa0f7235b
ToppCelldroplet-Liver-nan-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNIK LAMA4 ARHGEF15 ARAP3 RBM46 INPP5J

1.37e-051831266709a486154b3157427deb3b8886b63ac39ea42dd
ToppCelldroplet-Liver-nan-3m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNIK LAMA4 ARHGEF15 ARAP3 RBM46 INPP5J

1.37e-051831266dc06f19f6f80f4c7f13f1f990c1fe0f91ba64ea7
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SYNPO SHANK3 ARHGEF15 ZNF385D ARAP3 HMCN1

1.37e-051831266dc19857b66dcadbf7c87de91f7b1f4e8ef2857ed
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SYNPO SHANK3 ARHGEF15 ZNF385D ARAP3 HMCN1

1.37e-0518312664759560e5b4f4e5a00e5f933e3451a27c7c4aefe
ToppCellCOVID-19-Neuronal_cells-Neuronal_cells|COVID-19 / group, cell type (main and fine annotations)

DLGAP2 SASH1 LAMA4 SHANK3 ZNF385D OSBP2

1.46e-0518512664a095829992b39856a73bdfac03ee68b9aa0d3b8
ToppCellCOVID-19-Neuronal_cells|COVID-19 / group, cell type (main and fine annotations)

DLGAP2 SASH1 LAMA4 SHANK3 ZNF385D OSBP2

1.46e-05185126636ce23893915f5c380cca39b2c33a516edf31c3a
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

DLGAP2 NCKAP5 SYNPO ZNF385D PAK3 RPL13

1.50e-0518612667def03dd856b765bd3f493288641981c4f7fd26e
ToppCellAdult-Endothelial-endothelial_cell_of_lymph_vessel-D175|Adult / Lineage, Cell type, age group and donor

DLGAP2 LAMA4 SHANK3 ZNF385D ARAP3 OSBP2

1.55e-0518712661e52d3d9d664c813d859b5b75e4c07b218818f95
ToppCellCOVID-19-Heart-CM_4|Heart / Disease (COVID-19 only), tissue and cell type

TNIK NR4A3 EXTL3 TECRL OSBPL6 CDH2

1.70e-0519012663729648a17093b438398b82e32bbccc3af7b8c5d
ToppCell10x5'v1-week_17-19-Endothelial-stroma-proliferating_EC|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

SASH1 LAMA4 SYNPO SHANK3 ARHGEF15 HMCN1

1.75e-051911266dc9e5eb6aa31b8d79aeec33e59b9138dfb469a3b
ToppCellfacs-Lung-nan-3m-Endothelial-Capillary_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SASH1 NCKAP5 SHANK3 ARHGEF15 ARAP3 HMCN1

1.80e-0519212664bab9754cfd8b9c2d7cc1490e8a29f58c3c26f6c
ToppCelldroplet-Liver-LIVER_HEP-30m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLYWCH1 LAMA4 SHANK3 ARHGEF15 ARAP3 NAV1

1.85e-051931266826b8dd801298b3e0cd76232feae5a14026b8806
ToppCellLPS-antiTNF-Endothelial-Endothelial-Gen_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SASH1 NCKAP5 SHANK3 ARHGEF15 ARAP3 HMCN1

1.85e-0519312666e1982d089a9de628e6006d23ff78a223fbd9f47
ToppCelldroplet-Liver-LIVER_HEP-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLYWCH1 LAMA4 SHANK3 ARHGEF15 ARAP3 NAV1

1.85e-05193126687d3a577d37fb0cb4b6313c596310de452bc3872
ToppCellCOVID-19-kidney-FLT1+PLVAP+EC|kidney / Disease (COVID-19 only), tissue and cell type

SASH1 SYNPO SHANK3 ARHGEF15 NAV1 ACSL5

1.85e-051931266479abb1cd2eb978b8a4fdb900069a6329fc8cade
ToppCell10x5'v1-week_17-19-Endothelial|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

SASH1 LAMA4 SYNPO SHANK3 ARHGEF15 HMCN1

1.91e-051941266e141beafc9252e5d8c949252bfab53e127c881dc
ToppCell10x5'v1-week_17-19-Endothelial-stroma|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

SASH1 LAMA4 SYNPO SHANK3 ARHGEF15 HMCN1

1.91e-051941266953578102ffc7b612ee8fce45e414750800fef5d
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Acinar_Adenocarcinoma|TCGA-Lung / Sample_Type by Project: Shred V9

DLGAP2 RGL3 MYO15A TAF1L LRRC75A

1.91e-051151265eae0227fbdffe41656d924d74dc885d7f5d5f73d
ToppCellCOVID-19-kidney-PLVAP+EC|kidney / Disease (COVID-19 only), tissue and cell type

SASH1 SYNPO SHANK3 ARHGEF15 ARAP3 NAV1

1.96e-051951266a436483fec137584611f86b7a498a4dc2aa19cd3
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SYNPO SHANK3 STK10 ARAP3 NAV1 AGTPBP1

1.96e-0519512666bdef651cf73d7381e5012d0eb3c809138fb6b92
ToppCellE16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-matrix_-_immature_1|E16.5-samps / Age Group, Lineage, Cell class and subclass

NRIP2 SH2B3 WDR7 C16orf46 AHRR

1.99e-051161265f32f7eddfe33adb3b5cf7c34667a481a305c5163
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SASH1 SYNPO SHANK3 ARHGEF15 ARAP3 NAV1

2.02e-0519612667cbb19108b4553ef60ef5c230a29de1662c02efe
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SASH1 SYNPO SHANK3 ARHGEF15 ARAP3 NAV1

2.02e-0519612664cd1e6b7a791e11a40b19f971b7011bd11fe6273
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SASH1 SYNPO SHANK3 ARHGEF15 ARAP3 NAV1

2.02e-051961266d37f714d4fb57e958f3738fdda085560813e5bb5
ToppCellCOVID-19-kidney-VWF+PLVAP+EC|kidney / Disease (COVID-19 only), tissue and cell type

LAMA4 SYNPO SHANK3 ARHGEF15 ARAP3 NAV1

2.02e-051961266b71b197cb92117dd9efaa13de000841901cc4ca8
ToppCellPBMC-Control-cDC_3|Control / Compartment, Disease Groups and Clusters

BICD2 SH2B3 STK10 PI4KA NAV1 ACSL5

2.02e-05196126609d197b321ff9f13c0672ea059c850845b0dbbd5
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SYNPO SHANK3 ARHGEF15 ZNF385D ARAP3 HMCN1

2.08e-051971266c10dd1aaec01fb662eac83dfde90e3e426665d65
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SYNPO SHANK3 ARHGEF15 ZNF385D ARAP3 HMCN1

2.08e-0519712662844dbcd0a673ed81c99920aa45858651a00736d
ToppCelltumor_Lung-Endothelial_cells-Tumor_ECs|tumor_Lung / Location, Cell class and cell subclass

LAMA4 SYNPO SHANK3 ARHGEF15 ZNF385D ARAP3

2.14e-0519812665228c4bf2513186140c2c4eaa67a268c732bdc84
ToppCellParenchymal-NucSeq-Endothelial-Endothelia_lymphatic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DLGAP2 LAMA4 SHANK3 ZNF385D ARAP3 OSBP2

2.14e-0519812669ab0db78394e730f6866b2db80047149024ad5f6
ToppCell5'-Adult-Appendix-Endothelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SASH1 LAMA4 SHANK3 ARHGEF15 ZNF385D ARAP3

2.14e-05198126690e85fe7a0ab376a41666dfff6c0e95b7f1c9475
ToppCellParenchymal-NucSeq-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DLGAP2 LAMA4 SHANK3 ZNF385D ARAP3 OSBP2

2.14e-051981266e47d0e2c6353315c85d7007742bb16b0f05795ed
ToppCellParenchymal-NucSeq-Endothelial-Endothelia_vascular-VE_alveolar_capillary_Car4_aerocyte|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SASH1 SYNPO SHANK3 ARHGEF15 ARAP3 NAV1

2.20e-051991266dc88ce36cc066eb6c28cfd5b9b60fe07f8cc7b53
ToppCellCaecum-(5)_Dendritic_cell-(51)_cDC1|Caecum / shred on region, Cell_type, and subtype

SH2B3 NCKAP5 TLR8 NAV1 SDC2 INPP5J

2.20e-0519912662b97fda45241b2ce7be904cf081cabcf3eb5ba1d
ToppCellCaecum-Dendritic_cell-cDC1|Caecum / Region, Cell class and subclass

SH2B3 NCKAP5 TLR8 NAV1 SDC2 INPP5J

2.20e-0519912669ab38a0060a883de6fe3da8cdac42e124d7981d9
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Neuronal|10w / Sample Type, Dataset, Time_group, and Cell type.

ZNF385D CHD5 NAV1 PAK3 NHLH2 CCNI

2.26e-052001266979258173b82f37aeaaedd53b4a527da1dbe1b80
ToppCellCOVID-19_Mild-Neu_4|World / 5 Neutrophil clusters in COVID-19 patients

SASH1 ZDHHC8 CHD5 NPIPA5 OSBP2

2.74e-0512412655ef9eb806fb2c8ee5aae0a75503d244b08ee10d4
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Angpt2_(Angpt2)--|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

LRRC63 TECRL ASCL3 HMCN1

4.40e-0569126473b7accba3060705dcd6240e0ff47d68f2014ddd
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Angpt2_(Angpt2)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

LRRC63 TECRL ASCL3 HMCN1

4.40e-056912644e2e86e1da2ded562252774dc49e1b0b4274259f
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Angpt2_(Angpt2)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

LRRC63 TECRL ASCL3 HMCN1

4.40e-056912643b1b8b8f85440a7a88d52969bdff384a0c1a5470
ToppCellFetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DLGAP2 TSGA13 AP3B2 ZFHX2 ALK

5.24e-051421265819e983688d126d89a71abc03d72525cc759a347
ToppCellVE-Treg-naive_CD4|VE / Condition, Cell_class and T cell subcluster

TTLL3 UGGT1 HS1BP3 ARAP3 HMCN1

8.19e-0515612656501baf73616e702946de9fb13d267e30a68888b
ToppCellBronchial-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

RGL3 ZNF385D HMCN1 OSBPL6 CDH2

8.96e-0515912657cda111bb98f1241989e49d490bdf51a712ea589
ToppCellVE-mono3|VE / Condition, Cell_class and T cell subcluster

RGL3 CHST6 NR4A3 ARHGEF15 SDC2

9.50e-0516112657df3fefc55ab43b897fc78d1f0c7383b10ac33d5
ToppCellVE-mono3-|VE / Condition, Cell_class and T cell subcluster

RGL3 CHST6 NR4A3 ARHGEF15 SDC2

9.50e-0516112654e45bf7eceb0ee30dec4d8852778366776ea5a8f
ToppCellSubstantia_nigra-Macroglia-POLYDENDROCYTE-P2|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

FANCA AHRR MYMK SBK2

9.51e-058412641f8b19b159f83655f66cb99f8d10d9a87c08f78f
ToppCellSubstantia_nigra-Macroglia-POLYDENDROCYTE-P2-Tnr-Polydendrocyte.Tnr.Bmp4_(Bmp4)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

FANCA AHRR MYMK SBK2

9.51e-05841264c37e1170d39ad015f724e373a547ea5b6ba45a84
ToppCellSubstantia_nigra-Macroglia-POLYDENDROCYTE-P2-Tnr-Polydendrocyte.Tnr.Bmp4_(Bmp4)-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

FANCA AHRR MYMK SBK2

9.51e-058412647e4a76b65b0d34d9950f8b02590ff5a4b4534a27
ToppCellSubstantia_nigra-Macroglia-POLYDENDROCYTE-P2-Tnr|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

FANCA AHRR MYMK SBK2

9.51e-05841264503490e9408d9638bcd089ef8ec0521924df9a5d
ToppCellfacs-Pancreas-Exocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTLL3 SLC39A2 CTDSPL2 NCKAP5L CHD5

1.01e-041631265953a7db7e90a913e81002d2141fbbd5f1fdf2197
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SHANK3 ARHGEF15 AHRR ARAP3 NAV1

1.07e-041651265a74751e0ec857aa974bec04ccc747c004a8f6e01
ToppCellCOVID-19-kidney-Lymphatic_EC|kidney / Disease (COVID-19 only), tissue and cell type

DLGAP2 LAMA4 SHANK3 ZNF385D SH3PXD2B

1.13e-04167126597d0fea1f41c1c00e36d9b5c4c1f0dd85087056f
ToppCellAdult-Endothelial-endothelial_cell_of_artery-D122|Adult / Lineage, Cell type, age group and donor

SHANK3 ARHGEF15 ARAP3 HMCN1 C3orf36

1.16e-0416812658c3e1e45b422813bcdfa4273b1167db649a312f5
ToppCellPosterior_cortex-Hematopoietic-MICROGLIA-MI2(C1qb)-MICROGLIA_Microglia.C1qb.Tmem119_(Microglia.C1qb.Tmem119)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

ABCC3 TEX47 MYMK NHLH2

1.19e-04891264a4c2e364f8017dd9631f5ef06bdabdb2ebed1db8
ToppCellPosterior_cortex-Hematopoietic-MICROGLIA-MI2(C1qb)-MICROGLIA_Microglia.C1qb.Tmem119_(Microglia.C1qb.Tmem119)--|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

ABCC3 TEX47 MYMK NHLH2

1.19e-04891264c9c3fce307f14e90cc0d24e9611c454010a60869
ToppCellPosterior_cortex-Hematopoietic-MICROGLIA-MI2(C1qb)-MICROGLIA_Microglia.C1qb.Tmem119_(Microglia.C1qb.Tmem119)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

ABCC3 TEX47 MYMK NHLH2

1.19e-048912642e5da863e68a8fe378a34b67e4703013b731a7a4
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage|390C / Donor, Lineage, Cell class and subclass (all cells)

SLC29A3 NCKAP5 TLR8 PTPRO SDC2

1.23e-0417012653a7121d045f9ae54583b0f5f7436abf3665a1bce
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TNIK ZDHHC8 ARHGEF15 TOMM40 TAF1

1.23e-041701265adb625124832b0786a590e8f75b61e7263a1e0d4
ToppCellEndothelial-B-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

DLGAP2 LAMA4 SHANK3 ARHGEF15 PAK3

1.30e-041721265d4e98ff9c7cbc95457e1d71fa60f151a2f178dae
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell_prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SHANK3 ARHGEF15 ARAP3 NAV1 ACSL5

1.33e-041731265f193c63cc536d891c9d23043765e320252bb6e65
ToppCell3'-Child04-06-SmallIntestine-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LKAAEAR1 LAMA4 ARHGEF15 ZNF385D PAK3

1.33e-04173126585083b9ce20351dd69aa2327ad087b848b4307ff
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar-Macro_c3-EREG|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

TNIK SH2B3 NAT10 ALG3 SDC2

1.37e-041741265feed99acd868db61f045e666dbfdcaed91ca1488
ToppCellTCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Dedifferentiated_Liposarcoma-4|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

SASH1 NCKAP5 SLC18B1 SLC35E3 ACSL5

1.40e-04175126516849ea8f0985108baa2085f34c3de14a4f9f28b
ToppCellControl-Neuronal_cells-Neuronal_cells|Control / group, cell type (main and fine annotations)

DLGAP2 SASH1 LAMA4 SHANK3 ZNF385D

1.44e-04176126598c07d26ba0dc0fe15ca0ea81f633d4591782bd1
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2-Inh_L1-6_PVALB_SCUBE3_(Chandelier_1)|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LRRC63 ZNF385D ALK SDC2 INPP5J

1.44e-04176126595d5a4fdff1b9c715636684d22e06f8727ac0e7a
ToppCellControl-Neuronal_cells|Control / group, cell type (main and fine annotations)

DLGAP2 SASH1 LAMA4 SHANK3 ZNF385D

1.44e-041761265c29d09ecf0eb17f767d78af4b7f2e7725c967ff8
ToppCellControl|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SASH1 NCKAP5 SHANK3 ARHGEF15 ARAP3

1.48e-041771265b8ff6940e31b749776e81ae4f5bbd577dba9749c
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SYNPO SHANK3 ARHGEF15 ARAP3 NAV1

1.52e-0417812655f779a66aa42d1d8e8af17b4a08d5dcc733efd4c
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Dendritic-conventional_dendritic_cell|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

NR4A3 SYNPO PHLDA2 SDC2 RPL13

1.56e-041791265ba64bfb757d6e3be631ee95abfa24b47861f6a14
ToppCelldroplet-Liver-nan-3m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNIK LAMA4 ARHGEF15 ARAP3 NAV1

1.64e-041811265fcc94f04dae98b817ec06b282d2e887804d37ae5
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SASH1 LAMA4 SHANK3 ARAP3 OSBP2

1.64e-041811265e898ecb8d8f2eb2204225b7b0d665cadcd241139
ToppCelldroplet-Liver-nan-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNIK LAMA4 ARHGEF15 RBM46 INPP5J

1.64e-041811265a53f05c4c47465ee62e353716456bd09ab464b23
ToppCellCOVID-19-Endothelial_cells-Capillary_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

SASH1 NCKAP5 SHANK3 ARHGEF15 ARAP3

1.64e-041811265c5f9c92af1384d9089c65afdf41c6feb8345a3ae
ToppCelldroplet-Liver-Npc-21m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLYWCH1 LAMA4 SHANK3 ARAP3 NAV1

1.69e-041821265dc55de945c6f78f32eb3a1b3520835eb8417e068
ToppCelldroplet-Liver-Npc-21m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLYWCH1 LAMA4 SHANK3 ARAP3 NAV1

1.69e-041821265010a7364da46101cb5068891fd7bc712ea8f13bd
ToppCelldroplet-Liver-Npc-21m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLYWCH1 LAMA4 SHANK3 ARHGEF15 ARAP3

1.69e-041821265b1ec2015aad1181eac1bbf8d48ad6f2f7ed24a01
ToppCellNS-critical-d_07-13-Epithelial-Ionocyte|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

LAMA4 NCKAP5 ASCL3 CDH2 ALK

1.73e-041831265ba43bca2b45be1008eebd3f033cecb061fb3a966
ToppCellCOVID-19-Heart-CM_4|COVID-19 / Disease (COVID-19 only), tissue and cell type

NR4A3 EXTL3 TECRL OSBPL6 CDH2

1.73e-0418312652902b6e8aa9a6f62bc1a792c971ab7f651a8e676
ToppCell3'_v3-Lung-Myeloid_Dendritic-DC1|Lung / Manually curated celltypes from each tissue

NR4A3 NCKAP5 PAK3 OSBP2 CDH2

1.73e-041831265e4cbd39575b5a4612d9934532e3bad63286f8aa5
ToppCell3'_v3-lymph-node_spleen-Hematopoietic_progenitors-Progenitor_pre-Lymphocytic-T|lymph-node_spleen / Manually curated celltypes from each tissue

LKAAEAR1 SHANK3 ZNF385D BRCA2 MDC1

1.73e-0418312656c55fd737ed31f5b1aa41dc4dba7240521c19022
ToppCellCOPD-Myeloid-cDC1|World / Disease state, Lineage and Cell class

NR4A3 NCKAP5 PAK3 OSBP2 HPS5

1.77e-04184126542d7ce104cd7bcb83fbbbd0e7d3267ad07edfa94
ToppCellcritical-Epithelial-Ionocyte|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

LAMA4 NCKAP5 ASCL3 CDH2 ALK

1.77e-04184126558d36577eff814d46d72f031f3533d71549e3d6e
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRRC63 SASH1 MTMR10 CDH2 SDC2

1.77e-041841265da06ff24ee2b2cf4715fdfce43030b2da9e0aaf8
ToppCell(7)_DC_activated|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

NR4A3 SYNPO NAV1 CDH2 SDC2

1.77e-041841265b89871a3e36fde6daa68daf116f8c8d587554c0f
ToppCellCOVID-cycling-|COVID / Condition, Cell_class and T cell subcluster

C8orf48 FANCA CDCA2 BRCA2 OSBP2

1.82e-041851265eb74b8d36f7b749e04bc2ed4b36f7e1ac7bb6d5f
ToppCellCOVID-cycling|COVID / Condition, Cell_class and T cell subcluster

C8orf48 FANCA CDCA2 BRCA2 OSBP2

1.82e-0418512655112f966735fa48f0606adcfd5c0212ad5d3d77a
ToppCellControl-Endothelial_cells-Endothelial_cells_(other)|Control / group, cell type (main and fine annotations)

SASH1 SHANK3 ARHGEF15 ARAP3 NAV1

1.86e-041861265c6075fe84226b370c5139066793844ad33ae2db1
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TNIK ABCC3 NCKAP5 PTPRO CDH2

1.86e-041861265f28d72b47624b69a580b4429e2be560a26898591
ToppCell356C-Endothelial_cells-Endothelial-E-|356C / Donor, Lineage, Cell class and subclass (all cells)

LAMA4 SHANK3 ARHGEF15 OSBP2 TAF1L

1.86e-0418612652e024097ee361eeb1d855a4edb8ac8cdad35da06
DiseaseMYELODYSPLASTIC SYNDROME

ASXL1 SH2B3 FANCA BRCA2

1.64e-04671204C3463824
Diseasecytotoxicity measurement, response to clozapine

SHANK1 DLGAP2 HMCN1

2.22e-04291203EFO_0006952, GO_0097338
Diseasediastolic blood pressure, unipolar depression

SH2B3 HECTD4 SLC7A1

2.46e-04301203EFO_0003761, EFO_0006336
Diseaseproteinuria (implicated_via_orthology)

NCKAP5 SLC9A1 HPS5

2.46e-04301203DOID:576 (implicated_via_orthology)
Diseasereaction time measurement

TNIK BICD2 SH2B3 WDR7 HECTD4 NCKAP5 MED13L SLC35D1 PTPRO CDH2

3.66e-0465812010EFO_0008393
Diseasemyelofibrosis (is_implicated_in)

ASXL1 SH2B3

4.52e-0481202DOID:4971 (is_implicated_in)
Diseasebody mass index, coronary artery disease

NT5C2 TOMM40

4.52e-0481202EFO_0001645, EFO_0004340
Diseasecardiovascular disease

POLR1A SH2B3 RGL3 DLEU1 HS1BP3 SLC7A1 NT5C2 NAV1

5.77e-044571208EFO_0000319
Diseasehearing impairment

SLC29A3 FANCA SH3PXD2B MYO15A

7.00e-04981204C1384666
DiseaseFanconi anemia (is_implicated_in)

FANCA BRCA2

7.23e-04101202DOID:13636 (is_implicated_in)
Diseaseforced expiratory volume, body mass index

SH2B3 HECTD4

8.81e-04111202EFO_0004314, EFO_0004340
Diseasediabetic maculopathy

DLEU1 ALK

1.05e-03121202EFO_0010133
Diseasehair colour measurement, hair morphology measurement

FANCA RPL13

1.05e-03121202EFO_0007821, EFO_0007822
Diseaseskin melanoma (is_implicated_in)

FANCA BRCA2

1.45e-03141202DOID:8923 (is_implicated_in)
DiseaseFanconi anemia

FANCA BRCA2

1.45e-03141202cv:C0015625
DiseaseIschemic stroke, fibrinogen measurement

SH2B3 HECTD4 SHANK3

1.48e-03551203EFO_0004623, HP_0002140
DiseaseBMI-adjusted adiponectin measurement

DLEU1 ALK

1.66e-03151202EFO_0007737
DiseaseIschemic stroke, tissue plasminogen activator measurement

SH2B3 HECTD4

1.66e-03151202EFO_0004791, HP_0002140
Diseasefibrinogen measurement, factor VII measurement

SH2B3 HECTD4 SHANK3

1.72e-03581203EFO_0004619, EFO_0004623
Diseaseceliac disease

SH2B3 DLEU1 TLR8 NAV1

1.78e-031261204EFO_0001060
DiseaseIschemic stroke, plasminogen activator inhibitor 1 measurement

SH2B3 HECTD4

1.90e-03161202EFO_0004792, HP_0002140
Diseasecaudal anterior cingulate cortex volume measurement

DLEU1 ZNF385D

2.14e-03171202EFO_0010289
Diseasefactor XI measurement, Ischemic stroke

SH2B3 HECTD4

2.14e-03171202EFO_0004694, HP_0002140
DiseaseBone marrow hypocellularity

FANCA BRCA2

2.40e-03181202C1855710
Diseasevenous thromboembolism, fibrinogen measurement

SH2B3 HECTD4 SHANK3

2.60e-03671203EFO_0004286, EFO_0004623
DiseaseJuvenile Myelomonocytic Leukemia

ASXL1 SH2B3

2.68e-03191202C0349639
Diseasefactor VIII measurement, Ischemic stroke

SH2B3 HECTD4

2.68e-03191202EFO_0004630, HP_0002140
Diseaseskin pigmentation

TTLL3 FANCA OSBP2

2.83e-03691203EFO_0003784
DiseaseAdenocarcinoma of prostate

FANCA BRCA2

2.97e-03201202C0007112
DiseaseDisproportionate short stature

TRIP11 SLC35D1 SH3PXD2B

3.85e-03771203C0878659

Protein segments in the cluster

PeptideGeneStartEntry
LVFSKEPSKPLAPRI

ZNF385D

321

Q9H6B1
LASLLPFPPDIISKL

AHRR

51

A9YTQ3
PEPCSASLLLKKVPL

ARAP3

1196

Q8WWN8
RSPILLPKGLLAPEA

BICD2

581

Q8TD16
PALPLKTRSTPEFSL

CTDSPL2

276

Q05D32
KSDRDKPLPPLLARV

CHD5

1401

Q8TDI0
RSISEIKPPNLFPLA

NT5C2

526

P49902
LDFDPLLSPASPKRR

AKIRIN2

11

Q53H80
ILSLLRDPSKRKVPP

ALG3

316

Q92685
TRPQLLFSLPKLSPS

CCNI

161

Q14094
ALRLPPTSLKPDTFR

COMMD5

96

Q9GZQ3
SPKSAILPEPLLKSI

DLGAP2

456

Q9P1A6
PASFLLLIQKDLPPL

CCDC142

451

Q17RM4
LPKCERLPLPSFLLL

ARHGEF15

541

O94989
LEPPPTTLRKAFLAQ

C3orf36

46

Q3SXR2
FPKNRLPLPTIKSSF

AGTPBP1

326

Q9UPW5
SPSSLRALKEPLLPD

ASXL1

1166

Q8IXJ9
KLFLAPKPAPVLESS

AP3B2

601

Q13367
GPLTSRALLVLPPLK

C16orf46

201

Q6P387
PKTLGKLPTLPARLN

RBM46

341

Q8TBY0
RPRPRKPSFLKALLA

ABCC3

291

O15438
PFSLPFLKRLTLIKP

C8orf48

296

Q96LL4
FLPETLPLEKRAPSI

MFSD10

221

Q14728
HPFLKLAKPLSSLTP

PAK3

531

O75914
RLSKALFPPEPLVLR

PNPLA2

221

Q96AD5
KEFSLEPPSRPLVLK

LINS1

671

Q8NG48
LLPLKIPDACLFRPS

MED13L

961

Q71F56
LLSPLLPSIKPTVRK

MDC1

1066

Q14676
SPARGLKFLKLPPTS

NCKAP5L

451

Q9HCH0
LLPRRNSLILKPKPD

MTMR10

601

Q9NXD2
LSAALRSLPAEKPPA

MYO15A

2481

Q9UKN7
ALLHIFSRKPPEKPL

FAM90A1

116

Q86YD7
APRALSLLSLPPKKR

FLYWCH1

246

Q4VC44
SLPQPFLLSLRKRSP

LRRC75A

276

Q8NAA5
FTLVLKDRSPLLPGP

LRRC53

276

A6NM62
STHQFKKLLSLPPLP

HPS5

256

Q9UPZ3
LKPPCRLVELLPFSS

DLEU1

11

O43261
FFPISKDQPRVLLPL

EIF2B5

56

Q13144
SKLFPKIPPHSLRVL

PI4KA

206

P42356
PLLTFPSKEPLRSVL

PI4KA

831

P42356
AIRLELFLPPQLKPA

LKAAEAR1

151

Q8TD35
VDSFLPLLKSPLAAP

GCN1

881

Q92616
PLAAPRIKNPFLSLA

GCN1

891

Q92616
LLLRRPLPPKFTKLS

LRRC63

6

Q05C16
PLPLDLLPSFWKTLV

HECTD4

3716

Q9Y4D8
TKLPLSLDLPSPRPF

RGL3

581

Q3MIN7
VLKDLLPPTDARFRP

OSBPL6

841

Q9BZF3
FLRPESGSLPALKPL

OSBP2

136

Q969R2
TPRKDLPPLLLKLNE

NAT10

686

Q9H0A0
LKRPKRPLFNFALVP

HMCN1

71

Q96RW7
LRLVKLEPAPPKSLF

PTPRO

716

Q16827
AAASLPPLPRKVLFV

HS1BP3

86

Q53T59
LPRISSLPKSEKPLN

BRCA2

446

P51587
LPDIEPSPLRTFKAF

GLT6D1

121

Q7Z4J2
LPFSLKANRPPLEVL

DMRT3

241

Q9NQL9
SILKPLLPTPDLTLK

FAM117B

516

Q6P1L5
PKLSLPIRLLPEKDD

EXTL3

151

O43909
SHFLPALLTPRVLPK

FANCA

581

O15360
KTLKPTLFPAVPRLL

ACSL5

341

Q9ULC5
DKLPIFPDSARLPLT

ASCL3

11

Q9NQ33
FASKTPRPVTEPLLL

FAAH2

36

Q6GMR7
RDIASKKPLLSPIPE

CDCA2

581

Q69YH5
VPADKARSPAVPLLL

FRAT1

81

Q92837
LPSPQAEKRLPKLRL

CLPB

666

Q9H078
PLGSLLDRLKPPLAD

IL21R

441

Q9HBE5
PLLSNIRPDFSKAPL

CA5BP1

161

Q8WTZ4
SRPLPKILLTSAAPK

SDC2

71

P34741
TPLALKQLPKPRTSL

SBK2

86

P0C263
PFAFDLPLSPVTIKR

CDH2

636

P19022
SGRSIKFLLPPLSLL

MAP3K19

201

Q56UN5
KFLLPPLSLLPTRSG

MAP3K19

206

Q56UN5
RSKLILFPRKPSAPK

RPL13

121

P26373
PPEDRLSLKFLPSSE

DRICH1

71

Q6PGQ1
SSPVLLKLLFSPGPK

KRBA2

11

Q6ZNG9
ESLLTPRLAPSKPFT

LAMA4

1776

Q16363
LRLKAPFSELPFLPL

NRIP2

261

Q9BQI9
SPPSIIDKLFLDTLP

NR4A3

611

Q92570
KLAELPPTPLRATAK

NAV1

776

Q8NEY1
FPVPSASPKRRSKLL

FER1L6

56

Q2WGJ9
PPAEKLVLTRFLPLQ

GARIN2

111

Q8N9W8
PPLRPILKKTASLGF

SLC29A3

296

Q9BZD2
GRVKLLSPSILKPFP

POLR1A

666

O95602
SKRPLPLEPLLFLQV

TEX47

11

Q8TBZ9
SNLIPKLFRPAAFLP

SFXN4

101

Q6P4A7
ISSPLFGLLSDKRPP

SLC18B1

286

Q6NT16
RTPFKSPLLKGISAP

NCKAP5

966

O14513
SKLPLRIPPKSEGLL

NCKAP5

1366

O14513
FSLETKLPLSPPLVE

MOCS2

11

O96007
LSLKTPSERLLYPLP

NPIPA5

261

E9PKD4
PDTLPSPEALKFKIL

PLCZ1

281

Q86YW0
LRPSLFVLSPIKEPA

SYNPO

811

Q8N3V7
KLLPSVTELFPEFRP

TAF1L

241

Q8IZX4
KLLPSVTELFPEFRP

TAF1

221

P21675
SRSDPFTLNLLPKLP

PSG8

226

Q9UQ74
AFAELRKLLPTLPPD

NHLH2

96

Q02577
LDRNVPRKTFPLPLL

SLC35D1

101

Q9NTN3
PSPSKGPLRALVLLL

SLC39A2

156

Q9NP94
LSPTRLLSLPPDKPF

SHANK1

2076

Q9Y566
LLLPPSSSELKAGRP

ALK

71

Q9UM73
SLFPLLFTAPELPIK

ALG8

416

Q9BVK2
RIAEAATLKPPPFLR

CHST6

251

Q9GZX3
APSKARKLLPVLDPS

CNGA4

16

Q8IV77
LELLAPKSRSPSPGK

INPP5J

866

Q15735
LKPIFPLILSDDPTS

TSGA13

156

Q96PP4
VPPKLPSSLRKLFLS

TLR8

216

Q9NR97
PPLKASLSLRKEPVA

SPATA2

266

Q9UM82
ALFLIPRNPAPRLKS

TNIK

241

Q9UKE5
PFPIKPLSESKNRLL

ZDHHC20

321

Q5W0Z9
PSKSSIIPFRALKRP

ZER1

311

Q7Z7L7
KALISFLEPKLPARP

ZFHX2

286

Q9C0A1
LLISADNKPPPRLLS

PHF21B

181

Q96EK2
RDLLLPSPVSALKPL

SHANK3

1066

Q9BYB0
LSFKVPFLPVLPILS

SLC7A1

556

P30825
RALLVPPKAKPFLSN

SH3PXD2B

796

A1X283
LLKIAKSDPPTLLTP

STK10

246

O94804
LLSAARLFKLPPGPE

SASH1

1231

O94885
PKSLPSERILPALSK

SLC9A1

611

P19634
VLELFDPPKSSRPKL

SH2B3

236

Q9UQQ2
GKPLLRFPTALVLDP

TTLL3

721

Q9Y4R7
LSLFPASPRARPKEL

PHLDA2

36

Q53GA4
ATLEKKLPPLPLTLA

TOMM40

326

O96008
LLLKPISDVLPTFTP

TRIP11

1946

Q15643
LAVSLKPPFLRPELL

ZDHHC8

261

Q9ULC8
SLTKLPFPLSPILLS

ZNF295-AS1

76

Q8N0V1
LSKLVLSAGPLRPTP

TECRL

36

Q5HYJ1
CKALTFLLLQPPSPK

WDR7

1176

Q9Y4E6
IFAPKSLPPSRLLLL

SLC35E3

66

Q7Z769
ALLLTASERPKPLLF

UGGT1

166

Q9NYU2
LPKPLKSQASLLSLP

PP6455

71

Q8WZ26
AKLLLPTLSSLAFLP

MYMK

6

A6NI61
ATEPKKLPFPLSTLA

NECTIN3

381

Q9NQS3