Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionguanyl-nucleotide exchange factor activity

DOCK3 ARHGEF38 ARFGEF2 RALGPS1 HPS4 RAB3GAP2 HERC1

1.43e-04231987GO:0005085
GeneOntologyBiologicalProcessregulation of macroautophagy

ATP6V0A1 NUPR1 PIK3C3 RAB3GAP2 TLR2 FBXO7 WDR24

2.13e-05186937GO:0016241
DomainMCC-bdg_PDZ

MCC USHBP1

2.56e-052952PF10506
DomainUSH1C-bd_PDZ_domain

MCC USHBP1

2.56e-052952IPR019536
Domain-

IBTK UBR5 HERC1

1.83e-04229532.130.10.30
DomainRCC1/BLIP-II

IBTK UBR5 HERC1

2.10e-0423953IPR009091
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

TANC2 DOCK3 POLE ARFGEF2 LMTK2 ZZEF1 TNFRSF21 CCDC142 RALGPS1 USP40 NLRC5 HERC1 DHX34 WDR24

3.43e-0611051001435748872
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

TANC2 DCDC1 RNASEH2A FAT3 MCC ZZEF1 RAD51AP1 ZNF469 UBR5 TCF25 RERE DHX34 ANAPC4 TCTN2

3.84e-0611161001431753913
Pubmed

Semaphorin 3A alters endothelial cell immunogenicity by regulating Class II transactivator activity circuits.

SEMA3A CIITA

8.18e-062100224673430
Pubmed

NLRC5 negatively regulates LTA-induced inflammation via TLR2/NF-κB and participates in TLR2-mediated allergic airway inflammation.

TLR2 NLRC5

8.18e-062100230945291
Pubmed

NLR family member NLRC5 is a transcriptional regulator of MHC class I genes.

CIITA NLRC5

8.18e-062100220639463
Pubmed

NLRC5-CIITA Fusion Protein as an Effective Inducer of MHC-I Expression and Antitumor Immunity.

CIITA NLRC5

8.18e-062100237108368
Pubmed

Mutated in colorectal cancer (Mcc), a candidate tumor suppressor, is dynamically expressed during mouse embryogenesis.

MCC USHBP1

8.18e-062100222016184
Pubmed

NLRC5: a key regulator of MHC class I-dependent immune responses.

CIITA NLRC5

8.18e-062100223175229
Pubmed

A whole-genome RNAi screen identifies an 8q22 gene cluster that inhibits death receptor-mediated apoptosis.

GRHL2 UBR5

8.18e-062100221949371
Pubmed

Cutting edge: impaired MHC class I expression in mice deficient for Nlrc5/class I transactivator.

CIITA NLRC5

8.18e-062100222711889
Pubmed

Regulation of class I major histocompatibility complex (MHC) by nucleotide-binding domain, leucine-rich repeat-containing (NLR) proteins.

CIITA NLRC5

8.18e-062100222645137
Pubmed

Mycobacterium tuberculosis 19-kDa lipoprotein inhibits IFN-gamma-induced chromatin remodeling of MHC2TA by TLR2 and MAPK signaling.

CIITA TLR2

8.18e-062100216547269
Pubmed

NLRC5 exclusively transactivates MHC class I and related genes through a distinctive SXY module.

CIITA NLRC5

2.45e-053100225811463
Pubmed

Regulation of KIF1A-Driven Dense Core Vesicle Transport: Ca2+/CaM Controls DCV Binding and Liprin-α/TANC2 Recruits DCVs to Postsynaptic Sites.

TANC2 PPFIA2

2.45e-053100230021165
Pubmed

Epigenome-wide DNA methylation in hearing ability: new mechanisms for an old problem.

POLE TCF25

2.45e-053100225184702
Pubmed

Genome-wide analysis of copy-number variation in humans with cleft lip and/or cleft palate identifies COBLL1, RIC1, and ARHGEF38 as clefting genes.

COBLL1 ARHGEF38

2.45e-053100236493769
Pubmed

The Warburg Micro Syndrome-associated Rab3GAP-Rab18 module promotes autolysosome maturation through the Vps34 Complex I.

PIK3C3 RAB3GAP2

2.45e-053100232248620
Pubmed

BCG Increased Membrane Expression of TRIM59 Through the TLR2/ TLR4/IRF5 Pathway in RAW264.7 Macrophages.

TRIM59 TLR2

4.89e-054100228820065
Pubmed

HIC1 Tumor Suppressor Loss Potentiates TLR2/NF-κB Signaling and Promotes Tissue Damage-Associated Tumorigenesis.

HIC1 TLR2

4.89e-054100225934696
Pubmed

GWAS findings for human iris patterns: associations with variants in genes that influence normal neuronal pattern development.

SEMA3A HERC1

4.89e-054100221835309
Pubmed

Discovery and Characterization of ZUFSP/ZUP1, a Distinct Deubiquitinase Class Important for Genome Stability.

DMXL2 POLE WDHD1 UBR5 USP40

6.87e-05147100529576527
Pubmed

PKCθ synergizes with TLR-dependent TRAF6 signaling pathway to upregulate MUC5AC mucin via CARMA1.

TLR2 MUC5AC

8.14e-055100222303480
Pubmed

HIC1 epigenetically represses CIITA transcription in B lymphocytes.

HIC1 CIITA

8.14e-055100227720955
Pubmed

Comparative analysis of cobalamin binding kinetics and ligand protection for intrinsic factor, transcobalamin, and haptocorrin.

TCN2 CUBN

8.14e-055100211788601
Pubmed

SR protein kinases promote splicing of nonconsensus introns.

DOCK3 MYOM1 RAPH1 ABCA13 RASL12 CFAP20DC WDR24

8.57e-05361100726167880
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

LMTK2 ZZEF1 IBTK ATP11B RALGPS1 HPS4 MED12L DHX34

1.49e-04529100814621295
Pubmed

Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy.

ATP6V0A1 CMYA5 GRHL2 GMNC IBTK ATP11B RALGPS1 RAB3GAP2 FBXO7

1.65e-04686100929987050
Pubmed

Functional interactions between Fat family cadherins in tissue morphogenesis and planar polarity.

FAT3 RERE

1.70e-047100222510986
Pubmed

Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

LMTK2 TCF25 ZFHX2 PLCH1

2.37e-04104100410470851
Pubmed

A census of human transcription factors: function, expression and evolution.

FLI1 HIC1 IKZF3 PRDM4 GRHL2 WDHD1 ATOH8 ZFHX2 NKX3-1 RERE

2.91e-049081001019274049
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

PPFIA2 ARHGEF38 GRHL2 CFAP20DC ATP11B PIK3C3 RALGPS1 USP40 NLRC5 ZFHX2 RERE TMEM181 MOCOS

3.43e-0414891001328611215
Pubmed

GemC1 controls multiciliogenesis in the airway epithelium.

GMNC MUC5AC

3.63e-0410100226882546
Pubmed

Genome-wide association study of clinical dimensions of schizophrenia: polygenic effect on disorganized symptoms.

KIF26B NLRC5

4.43e-0411100223212062
Pubmed

FBXO11 constitutes a major negative regulator of MHC class II through ubiquitin-dependent proteasomal degradation of CIITA.

CIITA NLRC5

4.43e-0411100237279268
Pubmed

Associations of folate, vitamin B12, homocysteine, and folate-pathway polymorphisms with prostate-specific antigen velocity in men with localized prostate cancer.

TCN2 CUBN

5.30e-0412100220852008
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

TANC2 DOCK3 DMXL2 COBLL1 CNTNAP4 ARHGAP28 PLCH1

5.68e-04493100715368895
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

DMXL2 POLE ZZEF1 IBTK TCF25 PLCH1 DHX34 MOCOS

5.87e-04650100838777146
Pubmed

Emx2 is required for growth of the hippocampus but not for hippocampal field specification.

GRIK4 NKX3-1

6.25e-0413100210729342
Pubmed

Progesterone induced Warburg effect in HEK293 cells is associated with post-translational modifications and proteasomal degradation of progesterone receptor membrane component 1.

PTPRK UBR5 PIK3C3

6.34e-0458100331067491
Pubmed

The transcription factors Grainyhead-like 2 and NK2-homeobox 1 form a regulatory loop that coordinates lung epithelial cell morphogenesis and differentiation.

GRHL2 SEMA3A

7.28e-0414100222955271
Pubmed

CUL2LRR1 , TRAIP and p97 control CMG helicase disassembly in the mammalian cell cycle.

POLE WDHD1

8.39e-0415100233590678
Pubmed

A candidate gene study of folate-associated one carbon metabolism genes and colorectal cancer risk.

TCN2 CUBN

8.39e-0415100220615890
Pubmed

A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.

HIC1 PRDM4 GRHL2 TRIM59 IBTK ATOH8 ZFHX2 NKX3-1

1.03e-03709100822988430
Pubmed

Assembly and Function of Heterotypic Ubiquitin Chains in Cell-Cycle and Protein Quality Control.

UBR5 ANAPC4

1.08e-0317100229033132
Pubmed

Genetic Screens Reveal FEN1 and APEX2 as BRCA2 Synthetic Lethal Targets.

POLE RAD51AP1 WDHD1 HERC1

1.12e-03157100430686591
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

SNX13 UBR5 RAB3GAP2 TCF25 RERE TMEM181

1.17e-03407100612693553
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

DOCK3 DMXL2 ATP6V0A1 ARFGEF2 CMYA5 PRDM4 TRIM59 FBN1 PTPRK HPS4 FBXO7

1.18e-0312851001135914814
Pubmed

Gestational folate deficiency alters embryonic gene expression and cell function.

CUBN SEMA3A

1.22e-0318100233302058
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

UBE2J1 ICE2 MCC IBTK WDHD1 RAB3GAP2 CTPS1 PLCH1

1.27e-03733100834672954
Pubmed

Genome-wide association study for refractive astigmatism reveals genetic co-determination with spherical equivalent refractive error: the CREAM consortium.

ABCA13 NLN

1.36e-0319100225367360
Pubmed

Proteomics characterization of abundant Golgi membrane proteins.

MAN2A1 SCAMP3

1.36e-0319100211042173
Pubmed

Identification of seven new prostate cancer susceptibility loci through a genome-wide association study.

LMTK2 NKX3-1

1.36e-0319100219767753
Pubmed

Multiple common variants for celiac disease influencing immune gene expression.

IL18RAP PTPRK CIITA

1.39e-0376100320190752
Pubmed

Prostate cancer risk-associated variants reported from genome-wide association studies: meta-analysis and their contribution to genetic Variation.

LMTK2 NKX3-1

1.50e-0320100220564319
Pubmed

Hedgehog signaling controls mesenchymal growth in the developing mammalian digestive tract.

FLI1 MUC5AC

1.82e-0322100220430747
Pubmed

Proteomic analysis of steady-state nuclear hormone receptor coactivator complexes.

WDHD1 UBR5 HERC1

1.92e-0385100316051665
Pubmed

Phosphoinositide 3-kinase-dependent inhibition of dendritic cell interleukin-12 production by Giardia lamblia.

PIK3C3 TLR2

1.99e-0323100219047410
Pubmed

Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.

DCDC1 ZZEF1 ZNF469 MUC5AC

2.12e-03187100426460568
Pubmed

Genetic contributions of nonautoimmune SWR mice toward lupus nephritis.

MCC NKX3-1

2.17e-0324100211739537
Pubmed

Gene network analysis in a pediatric cohort identifies novel lung function genes.

ARHGEF38 MED12L

2.17e-0324100224023788
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

UBE2J1 ATP6V0A1 MAN2A1 ARFGEF2 ZZEF1 SEMA3A FBN1 PTPRK SLC39A6 CDON

2.42e-0312011001035696571
Pubmed

Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.

DMXL2 MCC RAB3GAP2 SLC39A6 ARHGAP28

2.42e-03322100526514267
Pubmed

System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes.

UBR5 HERC1

2.54e-0326100226949039
Pubmed

Common genetic variants associated with cognitive performance identified using the proxy-phenotype method.

PPFIA2 NUPR1 RERE

2.56e-0394100325201988
Cytoband10p12.31

CUBN EBLN1

1.05e-0322100210p12.31
CytobandEnsembl 112 genes in cytogenetic band chr18q12

PIK3C3 SLC39A6 MOCOS

1.56e-031041003chr18q12
Cytoband18p11.31

MYOM1 ARHGAP28

1.84e-0329100218p11.31
GeneFamilyFibronectin type III domain containing

MYOM1 CMYA5 IGSF22 PTPRK CDON

3.88e-04160705555
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HGABA

TANC2 DOCK3 IKZF3 RAPH1 PPFIA2 SEMA3A NLN RGS6 PTPRK RALGPS1 CNTNAP4 ZFHX2 ANKRD18A KIF3C HERC1 CDON

3.31e-0611069816M39071
CoexpressionAtlasdev gonad_e13.5_F_MeioticGermCell_Oct_top-relative-expression-ranked_1000

TANC2 DOCK3 DMXL2 ICE2 POLE ARFGEF2 CUBN DDIAS CFAP20DC ATP11B WDHD1 USP40 MED12L MAP3K15 HERC1 CTPS1

1.37e-0682010016gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_1000
CoexpressionAtlasdev gonad_e13.5_F_MeioticGermCell_Oct_top-relative-expression-ranked_500

TANC2 DOCK3 DMXL2 POLE ARFGEF2 DDIAS CFAP20DC ATP11B WDHD1 MAP3K15 CTPS1

2.02e-0638510011gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_500
CoexpressionAtlasdev gonad_e13.5_F_MeioticGermCell_Oct_k-means-cluster#2_top-relative-expression-ranked_500

POLE ARFGEF2 DDIAS CFAP20DC ATP11B WDHD1 CTPS1

7.69e-061521007gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_k2_500
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_S-high|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK3 POLE DDIAS RAD51AP1 CFAP20DC WDHD1 MED12L

1.11e-071691007e7514956b2e4298222ec443f98b2f5289451786e
ToppCellCOVID-19-Heart-CM_+_Macrophage|Heart / Disease (COVID-19 only), tissue and cell type

DOCK3 DMXL2 NRAP MYOM1 CMYA5 TG TLR2

1.16e-0717010074232fe937909f93d3736988c707b8f95ce993398
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TANC2 BICDL2 ABCA13 ARHGEF38 LMTK2 CMYA5 MUC5AC

1.64e-0717910076e965e424eebef50f0202cff75f458be395cfca1
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA13 KIF26B PPFIA2 FAT3 GMNC CNTNAP4 PLCH1

1.98e-0718410072cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA13 KIF26B PPFIA2 FAT3 GMNC CNTNAP4 PLCH1

1.98e-071841007ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA13 KIF26B PPFIA2 FAT3 GMNC CNTNAP4 PLCH1

1.98e-0718410072b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)-Goblet_(bronchial)_L.0.4.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BICDL2 ABCA13 ARHGEF38 CMYA5 TCF25 ANKRD18A MUC5AC

1.98e-07184100701c19a830348ab0b9c02c1546a439de70ee10f97
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 KIF26B COBLL1 ARHGEF38 GRHL2 RGS6 MOCOS

2.46e-0719010074836ea19308d2a96694f12ab0653b7ce7b101d2f
ToppCellPCW_07-8.5-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

DOCK3 COBLL1 ARHGEF38 GRHL2 RALGPS1 PLCH1 MUC5AC

2.64e-071921007b99f8236ef4ccdc75c02abea381cae6453205f6f
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 DCDC1 ABCA13 COBLL1 ARHGEF38 GRHL2 PLCH1

2.84e-071941007e577d9e88390b36b5a09b97fe1026089892275a3
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HIC1 MYOM1 NUPR1 TNFRSF21 FBN1 CNTNAP4 KRT25

3.37e-071991007eeb7d370d4dfacf705306c72ccc4919ddefacff1
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FAT3 COBLL1 CMYA5 GMNC PTPRK PLCH1

3.09e-0617810060e1bedf991189d0ef9b40dac9281bdf4739333a1
ToppCellControl-Neu_4|World / 5 Neutrophil clusters in COVID-19 patients

TANC2 DMXL2 RNASEH2A ICE2 ARFGEF2 CIITA

3.74e-061841006ce7f044956613118ee2e9fb6af2455c3166cb414
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK3 PPFIA2 COBLL1 ARHGEF38 GRHL2 RALGPS1

4.23e-0618810062ee64bc73a2251fd9f374be759b442cf4ed0d19e
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2-D175|Adult / Lineage, Cell type, age group and donor

TANC2 ABCA13 COBLL1 ARHGEF38 GRHL2 PLCH1

4.23e-061881006ec38def1fdbb34ed9b30244806975bd5a4370164
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK3 PPFIA2 COBLL1 ARHGEF38 GRHL2 RALGPS1

4.36e-061891006f51cdc9a47371cab8ed9ae63a6f14da07ede446c
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

DOCK3 COBLL1 ARHGEF38 GRHL2 RALGPS1 PLCH1

4.36e-0618910067659c7bbd58ee959a159294fb8d17317bbcc5681
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 DOCK3 COBLL1 ARHGEF38 GRHL2 RGS6

4.49e-061901006bf4511395fa97efd1c1cd17cc9bebb0271ee7f0e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 DOCK3 COBLL1 ARHGEF38 GRHL2 RGS6

4.49e-061901006b6b8964b4910083499681b5fdf554e127b6a4c4e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 DCDC1 ABCA13 COBLL1 ARHGEF38 GRHL2

4.49e-0619010063fc9e18c7441c0ae8cda65753cc42d0520f4e116
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK3 DCDC1 ABCA13 FAT3 COBLL1 GRHL2

4.63e-061911006d0e9afe7b6334dd515d3e68892efdc76347a55e5
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 DOCK3 COBLL1 ARHGEF38 GRHL2 RGS6

4.63e-0619110062fa1b9e76a0ed2d2f0de74349e266cf4a5f51aad
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 RAPH1 COBLL1 GRHL2 MAP3K15 MOCOS

4.77e-061921006fd08ae787e936cfdb1ab8f19b0fd63005b462709
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CMYA5 NUPR1 TNFRSF21 PTPRK CNTNAP4 KRT25

4.92e-0619310067cd9671e0ac64f7f3607f564485c63abbb7e7a63
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

IKZF3 COBLL1 SQLE PRDM4 CIITA RERE

4.92e-06193100608696a99309f5b088692ddac8cca35413b5e810d
ToppCellPBMC-Severe-Myeloid-Neutrophil-immature_Neutrophil-Neu_4|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ABCA13 POLE RAD51AP1 FBN1 MED12L ANKRD18A

4.92e-061931006ccab6a0c76f574ef7e1d6d5f1e620376daf21bbf
ToppCell10x3'2.3-week_17-19-Mesenchymal_fibro-stroma-endosteal_fibroblast|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

GRIK4 RASL12 NUPR1 SEMA3A ARHGAP28 CDON

5.06e-06194100669362e13158033de44f90f3773db6c0f27de8cb3
ToppCellPBMC-Severe-Myeloid-Neutrophil-immature_Neutrophil-Neu_4|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ABCA13 POLE RAD51AP1 FBN1 MED12L ANKRD18A

5.06e-06194100623318a1b55895b5166c6151f488a94a09b4627ff
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

TANC2 COBLL1 ARHGEF38 LMTK2 PTPRK PLCH1

5.06e-06194100697534c8bba895a7913665e03ae4e5c4a6ad71daf
ToppCellPCW_07-8.5-Epithelial|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

DOCK3 COBLL1 ARHGEF38 GRHL2 RALGPS1 PLCH1

5.06e-061941006f63ceedb88a9abc8644ee94adfd541e7817c1e3a
ToppCellCOVID-19-Epithelial-Club,_Basal_cells|COVID-19 / Condition, Lineage and Cell class

BICDL2 ABCA13 CMYA5 SEMA3A PTPRK MUC5AC

5.37e-061961006dd32046067d93b9484cfbf1d7826a436a3d9f0e9
ToppCellPCW_13-14-Mesenchymal|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

FAT3 RASL12 NUPR1 SEMA3A FBN1 ARHGAP28

5.53e-06197100673a2085d2682d636726a5432d572ae2a3fbe1c3f
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar-Macro_c2-CCL3L1|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

DMXL2 LILRB3 HIC1 RAPH1 TCN2 TLR2

5.69e-0619810067b61f427ed5ca8ad563e5f112fba950a24c9d956
ToppCellBronchial-NucSeq-Epithelial-Epi_alveolar-AT2|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TANC2 COBLL1 ARHGEF38 PTPRK TLR2 PLCH1

5.69e-061981006f948391296c261c473d339069a6d0f20ccd6f38f
ToppCellParenchymal-NucSeq-Epithelial-Epi_alveolar-AT2|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TANC2 COBLL1 ARHGEF38 PTPRK TLR2 PLCH1

5.69e-0619810062e2a4e1756bba6f4fbe529559a97d2993c890b4b
ToppCellParenchymal-NucSeq-Epithelial-Epi_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TANC2 COBLL1 ARHGEF38 GRHL2 PTPRK PLCH1

5.86e-0619910068587bd98de7767a575088afbea07a1feb4516b9b
ToppCellPCW_10-12-Mesenchymal|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

FAT3 RASL12 NUPR1 SEMA3A FBN1 ARHGAP28

5.86e-061991006a09292de4c4447b8eee55d401808e43b817321cc
ToppCellCOVID-19_Severe-immature_Neutrophil|COVID-19_Severe / Disease condition and Cell class

ABCA13 POLE RAD51AP1 FBN1 MED12L ANKRD18A

5.86e-061991006f82fa9d651e78f9ebbe6264e00a48c54b1786a69
ToppCellCOVID-19_Severe-immature_Neutrophil-|COVID-19_Severe / Disease condition and Cell class

ABCA13 POLE RAD51AP1 FBN1 MED12L ANKRD18A

5.86e-06199100642ea0c19c455bdb0ae89b428d09c333104c670dc
ToppCellNeuronal-Excitatory-eC(RORB)-eC_1-FILIP1L|Neuronal / cells hierarchy compared to all cells using T-Statistic

COBLL1 GMNC PTPRK MED12L ARHGAP28 PLCH1

6.03e-062001006f6af5ef02625aaae21e885e1ebd195e34731e53a
ToppCellNeuronal-Excitatory-eC(RORB)-eC_1-FILIP1L-|Neuronal / cells hierarchy compared to all cells using T-Statistic

COBLL1 GMNC PTPRK MED12L ARHGAP28 PLCH1

6.03e-06200100653f61e28c3ad6399f63c54e06120ecb5ebbf90d9
ToppCellNeuronal-Excitatory-eC(RORB)-eC_1-FILIP1L--L3-5|Neuronal / cells hierarchy compared to all cells using T-Statistic

COBLL1 GMNC PTPRK MED12L ARHGAP28 PLCH1

6.03e-062001006c1f243ae929f7791e040437470033abf749b44cc
ToppCellSigmoid-Macrophage|Sigmoid / Region, Cell class and subclass

DMXL2 LILRB3 RAPH1 TNFRSF21 CIITA TLR2

6.03e-062001006b07ac0ff3b8530e99094678fed80f35949cafac8
ToppCellSigmoid-(6)_Macrophage|Sigmoid / shred on region, Cell_type, and subtype

DMXL2 LILRB3 RAPH1 TNFRSF21 CIITA TLR2

6.03e-0620010069e10cca4429de2c4c8c3c6cf2c9e28637a095be9
ToppCellfacs-Marrow-KLS-18m-Lymphocytic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HIC1 PTPRK USHBP1 NLRC5 CDON

2.55e-05154100537765512dfae557b9f6eb30a29463b93682a4404
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HIC1 CMYA5 PTPRK NLRC5 CDON

2.63e-051551005c58a5fb8d853f12204e961d633e83452eb12a659
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage_3|356C / Donor, Lineage, Cell class and subclass (all cells)

FAT3 SEMA3A DDIAS NKX3-1 CDON

2.63e-051551005e1a20e88b9c0eaf7ca7004acc0eda096d1588563
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HIC1 CMYA5 PTPRK NLRC5 CDON

2.63e-0515510059cb8c42c2e451b2d4dcd7154a4b1bfd21bbb7ea8
ToppCellPND07-28-samps-Epithelial-Epithelial-non_alveolar-Club_cell|PND07-28-samps / Age Group, Lineage, Cell class and subclass

ARHGEF38 CMYA5 GRHL2 KRT25 SPSB2

3.25e-051621005aed15eef32419b8a4e2afdb9776c2bf2802e96f1
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 PPFIA2 COBLL1 ARHGEF38 NKX3-1

3.25e-051621005373513f9d0e5007b2e10a8b78d4909dcce9e3b62
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

IKZF3 COBLL1 PRDM4 CIITA RERE

3.35e-0516310056bed27d2f67a430a847da5eb47878d14b4949c45
ToppCellPCW_07-8.5-Epithelial-Epithelial_ciliated-epi_ciliated_(14)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

DOCK3 DCDC1 ARHGEF38 GRHL2 RALGPS1

3.55e-0516510050c714e852f912b5749de4cb0895406673979b2e6
ToppCellPCW_07-8.5-Epithelial-Epithelial_ciliated|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

DOCK3 DCDC1 ARHGEF38 GRHL2 RALGPS1

3.55e-05165100582530f96aaefe28a13bad0474bbad043f127a86c
ToppCellfacs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l44-58|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NRAP MYOM1 FAT3 CMYA5 PLCH1

3.76e-051671005d78356bf0c473816dbabaee51984940bd822f84e
ToppCell5'-Adult-SmallIntestine-Epithelial-Tuft-related-Tuft|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TANC2 FAT3 ARHGEF38 CMYA5 ZFHX2

3.87e-0516810058072d0496b7b730c4601009eaa69ec5366d26d73
ToppCellControl|World / group, cell type (main and fine annotations)

COBLL1 RGS6 PTPRK PLCH1 MUC5AC

3.87e-051681005a3511faf2cd2c2b9c8363c8b99da3f3609c43ed6
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

POLE DDIAS RAD51AP1 CFAP20DC WDHD1

3.98e-051691005121768fc51fc3441ec725346a1bbe29e21d05971
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYOM1 ABCA13 FAT3 CUBN PLCH1

3.98e-05169100512bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-5_RORB_HSPB3|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COBLL1 CMYA5 GMNC PTPRK PLCH1

4.09e-051701005985c6c9e3c593ed0628a481f06c2c91b2ab5d746
ToppCellfacs-Heart-RA-18m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COBLL1 RASL12 TG RGS6 ZFHX2

4.21e-051711005b54d9d6b03c9c6f28a71cf2ed2bfa9a335bba949
ToppCellfacs-Heart-RA-18m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COBLL1 RASL12 TG RGS6 ZFHX2

4.21e-0517110059d825a2e799421af4f2cf4f4dc8e239b5d00476d
ToppCell343B-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

BICDL2 RAD51AP1 TLR2 NLRC5 MUC5AC

4.32e-051721005d65ffff3e341af34a043a0d802d7ba4b69de36e9
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-B_cell|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

IKZF3 COBLL1 PRDM4 CIITA RERE

4.45e-051731005d56e337eae727a29cd53cfd628e1b3c0a98e1f51
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_SEMA6D|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COBLL1 GMNC PTPRK MED12L PLCH1

4.45e-0517310059a2d42f8d9cb834856522661d524abb91c4637c5
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-5_RORB_CMAHP|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DCDC1 COBLL1 CMYA5 GMNC PLCH1

4.57e-051741005df5664da3b93c233509781429a9c6d7edf1b8944
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MCC GRIK4 TNFRSF21 SEMA3A ANKRD18A

4.70e-05175100590e29945aa861082c94bb4f331161adc3a6ef899
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_B-B_cell-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

COBLL1 RAD51AP1 IGSF22 RAB3GAP2 TCTN2

4.70e-05175100569ed3c7c45df6bef70f5f2ff003531160bf3b32b
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MCC GRIK4 TNFRSF21 SEMA3A ANKRD18A

4.82e-051761005e4b21fd6a5e0c5950f27c3e1868318e48330ae5e
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA13 FAT3 NUPR1 GRHL2 ATOH8

4.96e-051771005da8802a6351d3e510822f82e2fde8a4314a2216e
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FAT3 ZNF469 RGS6 PTPRK MED12L

5.09e-051781005ccea3c8908d72f5fecd151a133048c8e9758304c
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FAT3 COBLL1 GMNC PTPRK PLCH1

5.23e-0517910058766a5a066091879f521acfc612abf563ff78808
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

BICDL2 ARHGEF38 GRHL2 PTPRK TLR2

5.23e-051791005815b959ce8721c5ded70c0ca6e318dafc691746e
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Mesenchymal-brain_pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HIC1 RAPH1 NUPR1 PLCH1 SPSB2

5.23e-051791005f99500c4a590e5152ded5862690f7fa614d64a80
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Mesenchymal-Pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HIC1 RAPH1 NUPR1 PLCH1 SPSB2

5.23e-0517910057d61466181ab73088de3ec8a129d7cfa8cac7ecc
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Mesenchymal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HIC1 RAPH1 NUPR1 PLCH1 SPSB2

5.23e-0517910056c98ce32cb55cf9cee557449e41b23bdb22f5efd
ToppCellE16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TANC2 CFAP20DC KDF1 SPSB2 WDR24

5.51e-051811005f6629fa71bb94405f523f63a9264cacf6d15c5f4
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA13 FAT3 NUPR1 GRHL2 ATOH8

5.51e-051811005071f9bb5d39070cdc473d9b0e094d196bc702b56
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

RAPH1 KIF26B COBLL1 GRHL2 MOCOS

5.51e-051811005b7c85fbef3c06d5dc32a2a58f8d3dfabf1d79d9f
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-papillary_tips_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BICDL2 IKZF3 MCC TNFRSF21 SLC39A6

5.66e-051821005678eadd57e7e830fc2bf9fd35616d3badce01705
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-papillary_tips_cell-Papillary_Tip_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BICDL2 IKZF3 MCC TNFRSF21 SLC39A6

5.66e-0518210058d1229fa5aa6e2e38f2ac6fe4f4dc89752fe9344
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_VWA2|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MCC GRIK4 SEMA3A CNTNAP4 ANKRD18A

5.66e-05182100572e65a23cd36085bc880087d3cae92395de918a1
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MCC GRIK4 SEMA3A CNTNAP4 ANKRD18A

5.66e-05182100505c167158815bf25d509df59ab386e1990712765
ToppCellRA-13._Vascular_Smooth_Muscle|RA / Chamber and Cluster_Paper

PPFIA2 FAT3 COBLL1 RGS6 ARHGAP28

5.80e-051831005818fd886e0188091310825f9145fa53328f2c979
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

COBLL1 ARHGEF38 GRHL2 PTPRK PLCH1

5.80e-0518310056847c1252d6bb105524f812658112517fd351eab
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA13 NUPR1 GRHL2 RGS6 ATOH8

5.80e-051831005cfae90c309622b5d499e62a3a8a8b9746478d28d
ToppCellCF-Myeloid-Neutrophil|CF / Disease state, Lineage and Cell class

LILRB3 IL18RAP TG TLR2 DHX34

5.80e-051831005da43827952e6fdee2ce94648c316182f272b321c
ToppCellRA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

PPFIA2 FAT3 COBLL1 RGS6 ARHGAP28

5.80e-051831005cae2ee08f985a6f005b4b8e959e465350315156a
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GRIK4 TG SEMA3A RGS6 PTPRK

5.96e-0518410059a185e6ea86bbfbb48bfe88650a8c05ceba78d7f
ToppCellnormal_Lung-Fibroblasts-Myofibroblasts|normal_Lung / Location, Cell class and cell subclass

KIF26B PPFIA2 ZNF469 FBN1 ARHGAP28

5.96e-0518410050b336489c10e8c3c957795dd845454f03404382b
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 PPFIA2 COBLL1 ARHGEF38 GRHL2

5.96e-051841005d33de57876817050b294f2ecb0a4eb0634cfa7f0
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Endothelial_Myeloid-Endo-Endothelial-Endo_L2-5_CLDN5|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FLI1 TCN2 COBLL1 USHBP1 NLRC5

5.96e-05184100573eaac74a88bf5fd23d88035fac398ac43b268c5
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Endothelial_Myeloid-Endo|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FLI1 TCN2 COBLL1 USHBP1 NLRC5

5.96e-05184100565f651d4b93ed0b52f526d3f517d92b6c62aaec3
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA13 FAT3 NUPR1 GRHL2 ATOH8

5.96e-051841005da06ff24ee2b2cf4715fdfce43030b2da9e0aaf8
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Endothelial_Myeloid-Endo-Endothelial|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FLI1 TCN2 COBLL1 USHBP1 NLRC5

5.96e-0518410059001d35cdde061d06f8545b3cee942d1299129db
ToppCellCOVID-19-Heart-CM_1|COVID-19 / Disease (COVID-19 only), tissue and cell type

DOCK3 NRAP MYOM1 CMYA5 RGS6

5.96e-051841005e737f0f14c49b07bbb04a165083ac32210bc5690
ToppCellCOVID-19-Heart-CM_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

DOCK3 NRAP MYOM1 CMYA5 RGS6

6.11e-051851005549eeb521c3985bff396ea0f202db21822efa51f
ToppCellCOVID-19-Epithelial_cells-Airway_club|COVID-19 / group, cell type (main and fine annotations)

BICDL2 ARHGEF38 GRHL2 PTPRK PLCH1

6.11e-051851005cfe6fd73d817e173fe803bc1683c291d9bcb8608
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

BICDL2 ARHGEF38 GRHL2 PTPRK TLR2

6.27e-0518610052ea5ff14861e5f91d0e6a5767c403a24045d715c
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_adventitial_fibro_(9)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

HIC1 KIF26B NUPR1 RGS6 CDON

6.27e-0518610058915436d09775f2828a7678af203b1082b36e21c
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

TANC2 ABCA13 ARHGEF38 CTPS1 PLCH1

6.27e-051861005acfa68a2afb7d2b51c9b469a1965fe5cc5d5e64e
DrugHydrocotarnine hydrobromide [5985-00-2]; Down 200; 13.2uM; HL60; HG-U133A

FLI1 UBE2J1 SQLE UBR5 RAB3GAP2 PEX16 KIF3C TCTN2

1.43e-061849981772_DN
Diseasekeratoconjunctivitis (is_marker_for)

TLR2 MUC5AC

3.34e-053992DOID:9368 (is_marker_for)
Diseasesystemic scleroderma (implicated_via_orthology)

FLI1 FBN1

3.34e-053992DOID:418 (implicated_via_orthology)
Diseaseeye measurement

SEMA3A ZNF469 HERC1

1.01e-0427993EFO_0004731
DiseaseAnemia, Megaloblastic

TCN2 CUBN

1.11e-045992C0002888
Diseasecortical surface area measurement

TANC2 DCDC1 RAPH1 KIF26B FAT3 SNX13 TG GMNC ZNF469 FBN1 RALGPS1 RAB3GAP2 ARHGAP28 RERE

1.58e-0413459914EFO_0010736
Diseaseeosinophil percentage of leukocytes

DOCK3 FLI1 IKZF3 ICE2 IL18RAP TRIM59 TG NLRC5 RERE MUC5AC

2.07e-047469910EFO_0007991
Diseasebiliary tract benign neoplasm (is_marker_for)

CTPS1 MUC5AC

2.31e-047992DOID:0050625 (is_marker_for)
DiseaseAdenocarcinoma of large intestine

POLE MCC UBR5 MAP3K15

3.13e-0496994C1319315
Diseasecorpus callosum volume measurement

KIF26B TG SEMA3A GMNC

3.65e-04100994EFO_0010299
Diseaseeosinophil count

DOCK3 FLI1 IKZF3 ICE2 IL18RAP TRIM59 TG CIITA MED12L NLRC5 NKX3-1 RERE KDF1 MUC5AC

4.42e-0414889914EFO_0004842
Diseasedry eye syndrome (is_marker_for)

TLR2 MUC5AC

4.93e-0410992DOID:10140 (is_marker_for)
Diseasesystolic blood pressure, self reported educational attainment

SPSB2 CDON

4.93e-0410992EFO_0004784, EFO_0006335
Diseasemeningitis

RAPH1 RERE

6.01e-0411992MONDO_0021108
Diseasegastric adenocarcinoma (is_implicated_in)

ABCA13 UBR5

6.01e-0411992DOID:3717 (is_implicated_in)
Diseaseneuroimaging measurement

DCDC1 KIF26B FAT3 TG SEMA3A GMNC ZNF469 RALGPS1 RAB3GAP2 RERE PLCH1

9.21e-0410699911EFO_0004346
Diseasepulse pressure measurement, social deprivation

FBN1 CTPS1

9.88e-0414992EFO_0005763, EFO_0009696
Diseaseasthma, body mass index

PIK3C3 RERE

9.88e-0414992EFO_0004340, MONDO_0004979
Diseasebasophil measurement

FLI1 ZNF469 RERE

1.09e-0360993EFO_0803539
Disease3-hydroxyanthranilic acid measurement

TNFRSF21 TG

1.14e-0315992EFO_0010447
DiseaseGastro-enteropancreatic neuroendocrine tumor

IKZF3 CIITA

1.14e-0315992C2930967
Diseasecortical thickness

DCDC1 FAT3 ARFGEF2 TG SEMA3A GMNC ZNF469 FBN1 RALGPS1 RERE PLCH1

1.27e-0311139911EFO_0004840
DiseaseBenign neoplasm of stomach

POLE UBR5

1.47e-0317992C0153943
DiseaseNeoplasm of uncertain or unknown behavior of stomach

POLE UBR5

1.47e-0317992C0496905
DiseaseCarcinoma in situ of stomach

POLE UBR5

1.47e-0317992C0154060
Diseasesmoking status measurement

MAN2A1 NRAP FAT3 LMTK2 PTPRK RAB3GAP2 MED12L CNTNAP4 RERE HERC1 WDR24

1.77e-0311609911EFO_0006527
DiseaseAbnormality of refraction

DOCK3 FAT3 ZZEF1 SEMA3A FBN1 FBXO7 RERE MOCOS

1.95e-03673998HP_0000539
Diseaseelectroencephalogram measurement

CMYA5 PTPRK ARHGAP28

2.00e-0374993EFO_0004357
DiseaseStomach Carcinoma

POLE UBR5

2.24e-0321992C0699791
Diseasebrain connectivity measurement

KIF26B FAT3 SEMA3A GMNC TCF25 RERE

2.32e-03400996EFO_0005210
DiseaseColorectal Carcinoma

TCN2 ABCA13 POLE MCC CUBN TLR2 KDF1 ANAPC4

2.53e-03702998C0009402
Diseasebrain measurement, neuroimaging measurement

DCDC1 KIF26B FAT3 TG SEMA3A GMNC RALGPS1

2.56e-03550997EFO_0004346, EFO_0004464
Diseasechronic widespread pain

SNX13 CDON

2.69e-0323992EFO_0010099
DiseaseDrug toxicity

TCN2 TLR2 MOCOS

2.87e-0384993C0013221
DiseaseAdverse reaction to drug

TCN2 TLR2 MOCOS

2.87e-0384993C0041755
Diseaselow density lipoprotein cholesterol measurement, response to escitalopram, response to citalopram

GRHL2 SNX13

2.93e-0324992EFO_0004611, EFO_0006329, EFO_0007871
Diseasethalamus volume

DCDC1 FAT3 GMNC

2.96e-0385993EFO_0006935

Protein segments in the cluster

PeptideGeneStartEntry
EAEATALHLALQYSE

USHBP1

336

Q8N6Y0
HLQSGSESLLYHLSE

ANAPC4

351

Q9UJX5
SLHSSLATAINEYNE

ANKRD18A

421

Q8IVF6
TAFSSLQHLDLDALS

CIITA

981

P33076
DYSETLSNALNSCHD

ARHGEF38

396

Q9NXL2
SEALAYFITVNSESH

ARFGEF2

1691

Q9Y6D5
ENYLLSKNSSSHAAS

CNTNAP4

1016

Q9C0A0
ASYLAFSLSHDLQNS

ABCA13

1601

Q86UQ4
LHEAEALYSLASEES

CCDC142

466

Q17RM4
LHSLAASLSASIYQA

DMXL2

2256

Q8TDJ6
DTAISYKENHLAASS

COBLL1

571

Q53SF7
HISNCSVASDYLDLD

RAD51AP1

141

Q96B01
FDSSSSYLELLALHA

RASL12

106

Q9NYN1
PSHASYSLDDVTAQL

RAPH1

146

Q70E73
ADLQVSCSYDHLTTL

RALGPS1

241

Q5JS13
APSAINLDSHSYEIT

RGS6

396

P49758
SLARLADLDYSADHS

ATOH8

281

Q96SQ7
YESVSQLNSLDFHLD

RAB3GAP2

646

Q9H2M9
HSTALDKEITSANYA

DCDC1

1276

M0R2J8
EYSASHKQDLLLGST

IL18RAP

156

O95256
SDLSFHDSLATFIAI

MED12L

1076

Q86YW9
LESASSNSHLADYVL

MAN2A1

721

Q16706
SLEDDISLAHSVYAT

NRAP

1081

Q86VF7
AASSAYLKSLVVHDN

HIC1

66

Q14526
EILSNLHNSSSDVSY

IBTK

476

Q9P2D0
LHNSSSDVSYVSDIN

IBTK

481

Q9P2D0
HYECLSLERAESLSS

KIF26B

1676

Q2KJY2
SSDEQDHYLDALLSS

HERC1

71

Q15751
AAIEEVYHSSLASLN

HPS4

566

Q9NQG7
SHSYDESLSTLRFAN

KIF3C

346

O14782
ALDHSNSDLSSIYTS

DDIAS

206

Q8IXT1
ASYLDSVHALEEANA

KRT25

91

Q7Z3Z0
LAYTNSALDKSLSSH

LMTK2

1236

Q8IWU2
SYVSTSPLDLSAHQA

MOCOS

241

Q96EN8
ASEASQDVTYAQLHS

LILRB3

586

O75022
SSLELYAALCASHDI

MUC5AC

5186

P98088
DHASDAYTALLSSVL

POLE

181

Q07864
DSQDFSSYLSDGLHL

IAH1

186

Q2TAA2
LDLSHNSISQESALY

NLRC5

1276

Q86WI3
SSLPHELLSSDNALY

CUBN

551

O60494
LHSESADLLISYNAG

EBLN1

176

P0CF75
NDSSAELSELHSAAL

MCC

11

P23508
IASNDHADAIYTVSL

IGSF22

141

Q8N9C0
QEGSYLLSHAAEDSS

ICE2

856

Q659A1
SLATHSAYLKDDQRS

GRHL2

196

Q6ISB3
HYSLSESAVLDSIKA

DOCK3

1936

Q8IZD9
HSLETLYQSADCSDA

FBXO7

181

Q9Y3I1
LLASYTSHGADANLE

FBN1

16

P35555
IYADSPLNATSALEH

CMYA5

326

Q8N3K9
LYSHLATDSVDPADS

CDON

271

Q4KMG0
SSLELSVAAAHEYLE

C17orf107

31

Q6ZR85
QALYELFSATDDSLH

SQLE

471

Q14534
SDYESVGELSLASLH

FAT3

4531

Q8TDW7
ESSLLAYNTTSHTDQ

FLI1

196

Q01543
SAASLQSELAHSLDD

BICDL2

291

A1A5D9
DSHLYASNISDTLFN

GRIK4

401

Q16099
ESAAVLNDYSLTKSH

IKZF3

21

Q9UKT9
ISAVLEAAQTYASHT

DHX34

391

Q14147
YSTQASAAAATAELL

SCAMP3

86

O14828
SYHNDARSSLSVSLE

PPFIA2

791

O75334
INSAVYSADESLSAH

PRDM4

786

Q9UKN5
YENHSATAESSRLLD

PTPRK

831

Q15262
SLLHTAAYLIQDGSD

PGBD3

56

Q8N328
NVILYHDTDADTALS

MAP3K15

151

Q6ZN16
ADSHELSELVYSASN

PEX16

41

Q9Y5Y5
SNVSSDDSVQLHAYI

SNX13

551

Q9Y5W8
SQEASQTLLDSVYSH

TNFRSF21

636

O75509
YNLNSLSHDTATGLI

RNASEH2A

111

O75792
IDDTSSANYSALASH

GMNC

201

A6NCL1
DSSLDESDLYSLAHS

NUPR1

21

O60356
EDSLELLSSHYTNPT

PIK3C3

361

Q8NEB9
SDSYASVIKALEHSA

CTPS1

311

P17812
ATSSAHLEDLAYLDE

TANC2

271

Q9HCD6
ERHLGSYLLDSENTS

NKX3-1

96

Q99801
TTLNALNTLHESGYD

RERE

361

Q9P2R6
LANSSSYHTFLLDEE

SEMA3A

51

Q14563
SDLISSITQDYHLDE

KDF1

276

Q8NAX2
HLSSQNIEESAYFDS

SLC39A6

406

Q13433
SSLQAGTKEDLYLHS

TCN2

61

P20062
ENADHISYLASSRQS

CFAP20DC

301

Q6ZVT6
SEGNLSYLSSLSHLN

ATP11B

446

Q9Y2G3
QSLHTNTSLDAASEY

NLN

586

Q9BYT8
LAFSASLSHLLSDQA

nan

46

Q6ZTK2
AFSTDSLELLLYHCS

ZFHX2

726

Q9C0A1
AELSTHYQNSAEFLS

TMEM181

526

Q9P2C4
LSNTLNYTIADLSHE

WDHD1

481

O75717
SDYEELLLANTAAHI

ARHGAP28

551

Q9P2N2
QTDHYAALLGSNSES

SPSB2

116

Q99619
ISESDLNHSFSLTDL

UBE2J1

196

Q9Y385
ASSHNTYLTGDQLLS

PLCH1

311

Q4KWH8
HFSLSSASLDQLDVL

ZNF469

716

Q96JG9
AYDAHTSENAPSLLI

ATP6V0A1

596

Q93050
ITDHLDTQYDASSLI

ZZEF1

496

O43149
LALYSAHLASAEDVD

ZZEF1

1906

O43149
DSSFSLLSVSHALYD

WDR24

611

Q96S15
FSSLGSLEHLDLSYN

TLR2

96

O60603
LEHSTDDYASFSRAL

TG

2566

P01266
EALHEQSSYILSSAE

USP40

1201

Q9NVE5
TSPYHVDSLLQLSDA

TCF25

281

Q9BQ70
VEIYANSSLTHNASE

TCTN2

141

Q96GX1
EASLSVYQSLSNSLH

TRIM59

366

Q8IWR1
AAALEASNASSYLTS

UBR5

1766

O95071
HALSSEVSRKAASAY

MYOM1

76

P52179