Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionvoltage-gated sodium channel activity

HCN2 SCN1A SCN3A SCN5A SCN7A SCN8A SCN9A

3.05e-1526287GO:0005248
GeneOntologyMolecularFunctionsodium channel activity

HCN2 SCN1A SCN3A SCN5A SCN7A SCN8A SCN9A

6.06e-1352287GO:0005272
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

HCN2 SCN1A SCN3A SCN5A SCN7A SCN8A SCN9A

3.04e-09171287GO:0015081
GeneOntologyMolecularFunctionsodium ion binding

SCN1A SCN3A SCN8A SCN9A

3.07e-0914284GO:0031402
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

CACNA1D HCN2 SLC30A1 SCN1A SCN3A SCN5A SCN7A SCN8A SCN9A

8.69e-09465289GO:0046873
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

CACNA1D ATP13A5 HCN2 SLC30A1 SCN1A SCN3A SCN5A SCN7A SCN8A SCN9A

1.18e-086642810GO:0008324
GeneOntologyMolecularFunctionmonoatomic cation channel activity

CACNA1D HCN2 SCN1A SCN3A SCN5A SCN7A SCN8A SCN9A

1.61e-08343288GO:0005261
GeneOntologyMolecularFunctionalkali metal ion binding

SCN1A SCN3A SCN8A SCN9A

4.53e-0826284GO:0031420
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

CACNA1D ATP13A5 HCN2 SLC30A1 SCN1A SCN3A SCN5A SCN7A SCN8A SCN9A

6.32e-087932810GO:0015075
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

CACNA1D HCN2 SLC30A1 SCN1A SCN3A SCN5A SCN7A SCN8A SCN9A

1.13e-07627289GO:0022890
GeneOntologyMolecularFunctionmonoatomic ion channel activity

CACNA1D HCN2 SCN1A SCN3A SCN5A SCN7A SCN8A SCN9A

1.52e-07459288GO:0005216
GeneOntologyMolecularFunctionchannel activity

CACNA1D HCN2 SCN1A SCN3A SCN5A SCN7A SCN8A SCN9A

4.23e-07525288GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

CACNA1D HCN2 SCN1A SCN3A SCN5A SCN7A SCN8A SCN9A

4.29e-07526288GO:0022803
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

CACNA1D HCN2 SLC30A1 SCN1A SCN3A SCN5A SCN7A SCN8A SCN9A

5.63e-07758289GO:0015318
GeneOntologyMolecularFunctiontransmembrane transporter activity

CACNA1D ATP13A5 HCN2 SLC30A1 SCN1A SCN3A SCN5A SCN7A SCN8A SCN9A

2.46e-0611802810GO:0022857
GeneOntologyMolecularFunctiontransporter activity

CACNA1D ATP13A5 HCN2 SLC30A1 SCN1A SCN3A SCN5A SCN7A SCN8A SCN9A

5.44e-0612892810GO:0005215
GeneOntologyMolecularFunctionankyrin binding

CACNA1D SCN5A

4.71e-0423282GO:0030506
GeneOntologyMolecularFunctioncAMP binding

CNBD2 HCN2

5.58e-0425282GO:0030552
GeneOntologyMolecularFunctionATP-dependent activity, acting on DNA

CHD6 EP400 TOP2A

7.33e-04127283GO:0008094
GeneOntologyMolecularFunctiongated channel activity

CACNA1D HCN2 SCN1A SCN7A

1.15e-03334284GO:0022836
GeneOntologyMolecularFunctionATP-dependent chromatin remodeler activity

CHD6 EP400

1.23e-0337282GO:0140658
GeneOntologyMolecularFunctioncyclic nucleotide binding

CNBD2 HCN2

1.36e-0339282GO:0030551
GeneOntologyMolecularFunctionhelicase activity

DDX20 CHD6 EP400

1.38e-03158283GO:0004386
GeneOntologyMolecularFunctionATP-dependent activity

ATP13A5 DDX20 CHD6 EP400 TOP2A

1.48e-03614285GO:0140657
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity

CACNA1D HCN2 SCN1A

2.06e-03182283GO:0005244
GeneOntologyMolecularFunctionvoltage-gated channel activity

CACNA1D HCN2 SCN1A

2.13e-03184283GO:0022832
GeneOntologyMolecularFunctioncatalytic activity, acting on DNA

CHD6 EP400 TOP2A

5.74e-03262283GO:0140097
GeneOntologyMolecularFunctioncatalytic activity, acting on a nucleic acid

DDX20 CHD6 EP400 TOP2A

1.19e-02645284GO:0140640
GeneOntologyMolecularFunctionPDZ domain binding

CACNA1D HCN2

1.28e-02123282GO:0030165
GeneOntologyBiologicalProcessmembrane depolarization during action potential

CACNA1D HCN2 SCN1A SCN3A SCN5A SCN8A SCN9A

2.30e-1436277GO:0086010
GeneOntologyBiologicalProcesscardiac muscle cell action potential

CACNA1D HCN2 SCN1A SCN3A SCN5A SCN7A SCN8A SCN9A

1.50e-1387278GO:0086001
GeneOntologyBiologicalProcesscardiac muscle cell action potential involved in contraction

CACNA1D SCN1A SCN3A SCN5A SCN7A SCN8A SCN9A

1.32e-1262277GO:0086002
GeneOntologyBiologicalProcesscardiac muscle cell contraction

CACNA1D SCN1A SCN3A SCN5A SCN7A SCN8A SCN9A

2.48e-1193277GO:0086003
GeneOntologyBiologicalProcessaction potential

CACNA1D HCN2 SCN1A SCN3A SCN5A SCN7A SCN8A SCN9A

1.34e-10201278GO:0001508
GeneOntologyBiologicalProcessmembrane depolarization

CACNA1D HCN2 SCN1A SCN3A SCN5A SCN8A SCN9A

1.62e-10121277GO:0051899
GeneOntologyBiologicalProcessactin-mediated cell contraction

CACNA1D SCN1A SCN3A SCN5A SCN7A SCN8A SCN9A

2.28e-10127277GO:0070252
GeneOntologyBiologicalProcessactin filament-based movement

CACNA1D SCN1A SCN3A SCN5A SCN7A SCN8A SCN9A

8.44e-10153277GO:0030048
GeneOntologyBiologicalProcesscardiac muscle contraction

CACNA1D SCN1A SCN3A SCN5A SCN7A SCN8A SCN9A

1.56e-09167277GO:0060048
GeneOntologyBiologicalProcesssodium ion transmembrane transport

HCN2 SCN1A SCN3A SCN5A SCN7A SCN8A SCN9A

7.17e-09208277GO:0035725
GeneOntologyBiologicalProcessstriated muscle contraction

CACNA1D SCN1A SCN3A SCN5A SCN7A SCN8A SCN9A

9.62e-09217277GO:0006941
GeneOntologyBiologicalProcessneuronal action potential

SCN1A SCN3A SCN5A SCN8A SCN9A

1.73e-0863275GO:0019228
GeneOntologyBiologicalProcesssodium ion transport

HCN2 SCN1A SCN3A SCN5A SCN7A SCN8A SCN9A

4.91e-08275277GO:0006814
GeneOntologyBiologicalProcessheart contraction

CACNA1D SCN1A SCN3A SCN5A SCN7A SCN8A SCN9A

8.49e-08298277GO:0060047
GeneOntologyBiologicalProcessheart process

CACNA1D SCN1A SCN3A SCN5A SCN7A SCN8A SCN9A

1.09e-07309277GO:0003015
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

CACNA1D ATP13A5 HCN2 SLC30A1 SCN1A SCN3A SCN5A SCN7A SCN8A SCN9A

1.56e-079422710GO:0098655
GeneOntologyBiologicalProcesstransmission of nerve impulse

SCN1A SCN3A SCN5A SCN8A SCN9A

3.17e-07112275GO:0019226
GeneOntologyBiologicalProcessregulation of membrane potential

CACNA1D HCN2 SCN1A SCN3A SCN5A SCN7A SCN8A SCN9A

3.90e-07559278GO:0042391
GeneOntologyBiologicalProcessmuscle contraction

CACNA1D SCN1A SCN3A SCN5A SCN7A SCN8A SCN9A

6.22e-07400277GO:0006936
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

CACNA1D ATP13A5 HCN2 SLC30A1 SCN1A SCN3A SCN5A SCN7A SCN8A SCN9A

7.42e-0711152710GO:0034220
GeneOntologyBiologicalProcessmonoatomic cation transport

CACNA1D ATP13A5 HCN2 SLC30A1 SCN1A SCN3A SCN5A SCN7A SCN8A SCN9A

1.04e-0611572710GO:0006812
GeneOntologyBiologicalProcessinorganic cation transmembrane transport

CACNA1D HCN2 SLC30A1 SCN1A SCN3A SCN5A SCN7A SCN8A SCN9A

1.55e-06922279GO:0098662
GeneOntologyBiologicalProcessmetal ion transport

CACNA1D HCN2 SLC30A1 SCN1A SCN3A SCN5A SCN7A SCN8A SCN9A

3.03e-061000279GO:0030001
GeneOntologyBiologicalProcessmembrane depolarization during cardiac muscle cell action potential

CACNA1D HCN2 SCN5A

3.48e-0623273GO:0086012
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

CACNA1D HCN2 SLC30A1 SCN1A SCN3A SCN5A SCN7A SCN8A SCN9A

3.48e-061017279GO:0098660
GeneOntologyBiologicalProcessmonoatomic ion transport

CACNA1D ATP13A5 HCN2 SLC30A1 SCN1A SCN3A SCN5A SCN7A SCN8A SCN9A

4.93e-0613742710GO:0006811
GeneOntologyBiologicalProcessmuscle system process

CACNA1D SCN1A SCN3A SCN5A SCN7A SCN8A SCN9A

4.97e-06547277GO:0003012
GeneOntologyBiologicalProcessblood circulation

CACNA1D SCN1A SCN3A SCN5A SCN7A SCN8A SCN9A

1.50e-05648277GO:0008015
GeneOntologyBiologicalProcessmembrane depolarization during SA node cell action potential

CACNA1D SCN5A

1.65e-055272GO:0086046
GeneOntologyBiologicalProcesscirculatory system process

CACNA1D SCN1A SCN3A SCN5A SCN7A SCN8A SCN9A

3.32e-05733277GO:0003013
GeneOntologyBiologicalProcessinorganic ion import across plasma membrane

CACNA1D HCN2 SLC30A1 SCN5A

3.34e-05142274GO:0099587
GeneOntologyBiologicalProcessinorganic cation import across plasma membrane

CACNA1D HCN2 SLC30A1 SCN5A

3.34e-05142274GO:0098659
GeneOntologyBiologicalProcessregulation of atrial cardiac muscle cell membrane repolarization

CACNA1D SCN5A

4.60e-058272GO:0060372
GeneOntologyBiologicalProcessregulation of membrane depolarization

CACNA1D HCN2 SCN5A

6.84e-0561273GO:0003254
GeneOntologyBiologicalProcessSA node cell to atrial cardiac muscle cell signaling

CACNA1D SCN5A

7.38e-0510272GO:0086018
GeneOntologyBiologicalProcessSA node cell action potential

CACNA1D SCN5A

7.38e-0510272GO:0086015
GeneOntologyBiologicalProcessatrial cardiac muscle cell membrane repolarization

CACNA1D SCN5A

9.01e-0511272GO:0099624
GeneOntologyBiologicalProcessSA node cell to atrial cardiac muscle cell communication

CACNA1D SCN5A

9.01e-0511272GO:0086070
GeneOntologyBiologicalProcessactin filament-based process

CACNA1D SCN1A SCN3A SCN5A SCN7A SCN8A SCN9A

1.32e-04912277GO:0030029
GeneOntologyBiologicalProcessimport across plasma membrane

CACNA1D HCN2 SLC30A1 SCN5A

2.16e-04230274GO:0098739
GeneOntologyBiologicalProcesssensory perception of mechanical stimulus

CACNA1D SCN1A SCN8A SCN9A

2.46e-04238274GO:0050954
GeneOntologyBiologicalProcessresponse to toxic substance

SLC30A1 SCN3A SCN8A SCN9A

5.14e-04289274GO:0009636
GeneOntologyBiologicalProcesssodium ion import across plasma membrane

HCN2 SCN5A

5.68e-0427272GO:0098719
GeneOntologyBiologicalProcessregulation of cardiac muscle cell membrane repolarization

CACNA1D SCN5A

7.02e-0430272GO:0099623
GeneOntologyBiologicalProcessbehavioral response to pain

SCN3A SCN9A

7.99e-0432272GO:0048266
GeneOntologyBiologicalProcesscell-cell signaling involved in cardiac conduction

CACNA1D SCN5A

9.02e-0434272GO:0086019
GeneOntologyBiologicalProcesspositive regulation of adenylate cyclase activity

CACNA1D LGR5

1.25e-0340272GO:0045762
GeneOntologyBiologicalProcesscardiac muscle cell membrane repolarization

CACNA1D SCN5A

1.31e-0341272GO:0099622
GeneOntologyBiologicalProcessregulation of heart rate by cardiac conduction

CACNA1D SCN5A

1.31e-0341272GO:0086091
GeneOntologyBiologicalProcessregulation of membrane repolarization

CACNA1D SCN5A

1.31e-0341272GO:0060306
GeneOntologyBiologicalProcesscellular homeostasis

CACNA1D ATP13A5 CHD6 SLC30A1 TM9SF4 SCN7A

1.43e-03981276GO:0019725
GeneOntologyBiologicalProcessdetection of stimulus involved in sensory perception of pain

SCN1A SCN9A

1.44e-0343272GO:0062149
GeneOntologyBiologicalProcesspositive regulation of cyclase activity

CACNA1D LGR5

1.79e-0348272GO:0031281
GeneOntologyBiologicalProcesspositive regulation of lyase activity

CACNA1D LGR5

1.87e-0349272GO:0051349
GeneOntologyBiologicalProcessadult walking behavior

SCN1A SCN8A

1.94e-0350272GO:0007628
GeneOntologyBiologicalProcessresponse to pain

SCN3A SCN9A

2.02e-0351272GO:0048265
GeneOntologyBiologicalProcessmembrane repolarization

CACNA1D SCN5A

2.43e-0356272GO:0086009
GeneOntologyBiologicalProcessdetection of mechanical stimulus involved in sensory perception

SCN1A SCN9A

2.52e-0357272GO:0050974
GeneOntologyBiologicalProcesscell communication involved in cardiac conduction

CACNA1D SCN5A

2.70e-0359272GO:0086065
GeneOntologyBiologicalProcessregulation of adenylate cyclase activity

CACNA1D LGR5

2.70e-0359272GO:0045761
GeneOntologyBiologicalProcesswalking behavior

SCN1A SCN8A

2.79e-0360272GO:0090659
GeneOntologyBiologicalProcessfemale gamete generation

DDX20 LGR5 TOP2A

3.01e-03223273GO:0007292
GeneOntologyBiologicalProcessregulation of cyclase activity

CACNA1D LGR5

3.67e-0369272GO:0031279
GeneOntologyBiologicalProcessregulation of lyase activity

CACNA1D LGR5

4.10e-0373272GO:0051339
GeneOntologyBiologicalProcessdetection of mechanical stimulus

SCN1A SCN9A

4.32e-0375272GO:0050982
GeneOntologyBiologicalProcessintracellular chemical homeostasis

CACNA1D ATP13A5 SLC30A1 TM9SF4 SCN7A

4.82e-03866275GO:0055082
GeneOntologyBiologicalProcessregulation of action potential

SCN5A SCN9A

5.02e-0381272GO:0098900
GeneOntologyCellularComponentvoltage-gated sodium channel complex

SCN1A SCN3A SCN5A SCN7A SCN8A SCN9A

3.13e-1417276GO:0001518
GeneOntologyCellularComponentsodium channel complex

SCN1A SCN3A SCN5A SCN7A SCN8A SCN9A

1.19e-1229276GO:0034706
GeneOntologyCellularComponentcation channel complex

CACNA1D HCN2 SCN1A SCN3A SCN5A SCN7A SCN8A SCN9A

4.18e-10235278GO:0034703
GeneOntologyCellularComponentmonoatomic ion channel complex

CACNA1D HCN2 SCN1A SCN3A SCN5A SCN7A SCN8A SCN9A

1.75e-08378278GO:0034702
GeneOntologyCellularComponenttransmembrane transporter complex

CACNA1D HCN2 SCN1A SCN3A SCN5A SCN7A SCN8A SCN9A

2.13e-07523278GO:1902495
GeneOntologyCellularComponenttransporter complex

CACNA1D HCN2 SCN1A SCN3A SCN5A SCN7A SCN8A SCN9A

3.12e-07550278GO:1990351
GeneOntologyCellularComponentT-tubule

CACNA1D SLC30A1 SCN1A SCN5A

3.10e-0679274GO:0030315
GeneOntologyCellularComponentplasma membrane protein complex

CACNA1D HCN2 SCN1A SCN3A SCN5A SCN7A SCN8A SCN9A

4.49e-06785278GO:0098797
GeneOntologyCellularComponentZ disc

CACNA1D SCN1A SCN5A SCN8A

4.03e-05151274GO:0030018
GeneOntologyCellularComponentI band

CACNA1D SCN1A SCN5A SCN8A

5.84e-05166274GO:0031674
GeneOntologyCellularComponentmembrane protein complex

CACNA1D ELOVL6 HCN2 SCN1A SCN3A SCN5A SCN7A SCN8A SCN9A

6.98e-051498279GO:0098796
GeneOntologyCellularComponentsarcolemma

CACNA1D SLC30A1 SCN1A SCN5A

9.85e-05190274GO:0042383
GeneOntologyCellularComponentsarcomere

CACNA1D SCN1A SCN5A SCN8A

2.78e-04249274GO:0030017
GeneOntologyCellularComponentnode of Ranvier

SCN1A SCN8A

3.01e-0420272GO:0033268
GeneOntologyCellularComponentmyofibril

CACNA1D SCN1A SCN5A SCN8A

3.94e-04273274GO:0030016
GeneOntologyCellularComponentcontractile muscle fiber

CACNA1D SCN1A SCN5A SCN8A

4.95e-04290274GO:0043292
GeneOntologyCellularComponentaxon initial segment

SCN1A SCN8A

6.38e-0429272GO:0043194
GeneOntologyCellularComponentaxon

HCN2 SCN1A SCN3A SCN5A SCN8A SCN9A

8.08e-04891276GO:0030424
GeneOntologyCellularComponentdendrite membrane

CACNA1D HCN2

2.37e-0356272GO:0032590
GeneOntologyCellularComponentintercalated disc

SCN1A SCN5A

3.47e-0368272GO:0014704
GeneOntologyCellularComponentneuronal cell body

CACNA1D HCN2 SCN1A SCN3A SCN8A

3.90e-03835275GO:0043025
GeneOntologyCellularComponentsomatodendritic compartment

CACNA1D HCN2 SLC30A1 SCN1A SCN3A SCN8A

4.14e-031228276GO:0036477
GeneOntologyCellularComponentpresynaptic active zone membrane

CACNA1D SCN8A

4.54e-0378272GO:0048787
GeneOntologyCellularComponentneuron projection membrane

CACNA1D HCN2

5.01e-0382272GO:0032589
GeneOntologyCellularComponentpresynaptic membrane

CACNA1D SCN1A SCN8A

5.32e-03277273GO:0042734
GeneOntologyCellularComponentmain axon

SCN1A SCN8A

5.87e-0389272GO:0044304
GeneOntologyCellularComponentcell body

CACNA1D HCN2 SCN1A SCN3A SCN8A

6.12e-03929275GO:0044297
GeneOntologyCellularComponentsynaptic membrane

CACNA1D SLC30A1 SCN1A SCN8A

6.31e-03583274GO:0097060
GeneOntologyCellularComponentcell-cell contact zone

SCN1A SCN5A

6.53e-0394272GO:0044291
HumanPhenoFocal impaired awareness seizure

CACNA1D SCN1A SCN3A SCN8A SCN9A

9.96e-0712695HP:0002384
HumanPhenoInfection-related seizure

HCN2 SCN1A SCN3A SCN8A SCN9A

2.01e-0614595HP:0032892
HumanPhenoSeizure precipitated by febrile infection

HCN2 SCN1A SCN3A SCN8A SCN9A

2.01e-0614595HP:0032894
HumanPhenoFebrile seizure (within the age range of 3 months to 6 years)

HCN2 SCN1A SCN3A SCN8A SCN9A

2.01e-0614595HP:0002373
HumanPhenoComplex febrile seizure

SCN1A SCN8A SCN9A

2.11e-061693HP:0011172
HumanPhenoGeneralized tonic seizure

HCN2 SCN1A SCN8A SCN9A

2.72e-066494HP:0010818
HumanPhenoClonic seizure

SCN1A SCN3A SCN8A SCN9A

7.04e-068194HP:0020221
HumanPhenoFocal hemiclonic seizure

SCN1A SCN8A SCN9A

8.61e-062593HP:0006813
HumanPhenoSimple febrile seizure

SCN1A SCN3A SCN8A

1.09e-052793HP:0011171
HumanPhenoBilateral tonic-clonic seizure

CACNA1D HCN2 SCN1A SCN3A SCN8A SCN9A

1.42e-0539496HP:0002069
HumanPhenoGeneralized clonic seizure

SCN1A SCN8A SCN9A

2.22e-053493HP:0011169
HumanPhenoDialeptic seizure

CACNA1D SCN1A SCN3A SCN8A SCN9A

2.99e-0525195HP:0011146
HumanPhenoFocal clonic seizure

SCN1A SCN8A SCN9A

4.23e-054293HP:0002266
HumanPhenoFocal motor seizure

CACNA1D SCN1A SCN8A SCN9A

4.76e-0513194HP:0011153
HumanPhenoTonic seizure

HCN2 SCN1A SCN8A SCN9A

6.19e-0514094HP:0032792
HumanPhenoPhotosensitive myoclonic seizure

SCN1A SCN9A

7.73e-05892HP:0001327
HumanPhenoCyanotic episode

SCN1A SCN9A

7.73e-05892HP:0200048
HumanPhenoImpulsivity

SCN1A SCN3A SCN8A SCN9A

7.90e-0514994HP:0100710
HumanPhenoGeneralized-onset seizure

CACNA1D HCN2 SCN1A SCN3A SCN8A SCN9A

9.15e-0554496HP:0002197
HumanPhenoSudden unexpected death in epilepsy

SCN1A SCN8A

1.24e-041092HP:0033258
HumanPhenoMotor seizure

CACNA1D HCN2 SCN1A SCN3A SCN8A SCN9A

1.40e-0458696HP:0020219
HumanPhenoFocal-onset seizure

CACNA1D SCN1A SCN3A SCN8A SCN9A

1.41e-0434695HP:0007359
HumanPhenoLimited neck range of motion

SCN1A SCN9A

1.51e-041192HP:0000466
HumanPhenoMultifocal epileptiform discharges

SCN1A SCN8A SCN9A

1.65e-046693HP:0010841
HumanPhenoEpilepsia partialis continua

SCN1A SCN9A

1.81e-041292HP:0012847
HumanPhenoFocal automatism seizure

SCN1A SCN8A

1.81e-041292HP:0032898
HumanPhenoGeneralized cerebral atrophy/hypoplasia

SCN1A SCN9A

2.14e-041392HP:0007058
HumanPhenoStatus epilepticus

SCN1A SCN3A SCN8A SCN9A

2.84e-0420794HP:0002133
HumanPhenoSecond degree atrioventricular block

CACNA1D SCN5A

2.88e-041592HP:0011706
HumanPhenoPhotosensitive tonic-clonic seizure

SCN1A SCN9A

2.88e-041592HP:0007207
HumanPhenoFacial tics

SCN1A SCN9A

2.88e-041592HP:0011468
HumanPhenoRigidity

SCN1A SCN3A SCN8A SCN9A

3.23e-0421494HP:0002063
HumanPhenoDysgenesis of the hippocampus

SCN1A SCN9A

3.29e-041692HP:0025101
HumanPhenoAtypical absence status epilepticus

SCN1A SCN9A

3.72e-041792HP:0011151
HumanPhenoFocal motor status epilepticus

SCN1A SCN9A

3.72e-041792HP:0032663
HumanPhenoEEG with spike-wave complexes

SCN1A SCN8A SCN9A

3.88e-048893HP:0010850
HumanPhenoEEG with abnormally slow frequencies

SCN1A SCN3A SCN8A

3.88e-048893HP:0011203
HumanPhenoGeneralized-onset motor seizure

HCN2 SCN1A SCN8A SCN9A

4.12e-0422894HP:0032677
HumanPhenoVisually-induced seizure

SCN1A SCN9A

4.18e-041892HP:0020216
HumanPhenoGeneralized non-convulsive status epilepticus without coma

SCN1A SCN9A

4.18e-041892HP:0032860
HumanPhenoAtonic seizure

HCN2 SCN1A SCN9A

4.72e-049493HP:0010819
HumanPhenoNon-convulsive status epilepticus without coma

SCN1A SCN9A

5.19e-042092HP:0032671
HumanPhenoBradycardia

CACNA1D SCN5A SCN9A

5.33e-049893HP:0001662
HumanPhenoTalipes valgus

SCN1A SCN9A

5.73e-042192HP:0004684
HumanPhenoFocal sensory seizure

SCN1A SCN8A

6.29e-042292HP:0011157
HumanPhenoReflex seizure

SCN1A SCN9A

6.29e-042292HP:0020207
HumanPhenoTibial torsion

SCN1A SCN9A

6.89e-042392HP:0100694
HumanPhenoMyoclonic seizure

CACNA1D SCN1A SCN8A SCN9A

7.02e-0426294HP:0032794
HumanPhenoEEG with generalized epileptiform discharges

SCN1A SCN3A SCN8A SCN9A

7.87e-0427094HP:0011198
HumanPhenoIntellectual disability, borderline

SCN3A SCN8A

8.15e-042592HP:0006889
HumanPhenoEpileptic aura

SCN1A SCN8A

8.15e-042592HP:0033348
HumanPhenoCyanosis

SCN1A SCN8A SCN9A

8.97e-0411793HP:0000961
HumanPhenoEEG with focal epileptiform discharges

SCN1A SCN8A SCN9A

9.19e-0411893HP:0011185
HumanPhenoEpileptic encephalopathy

SCN1A SCN3A SCN8A

9.42e-0411993HP:0200134
HumanPhenoLimited knee extension

SCN1A SCN9A

9.52e-042792HP:0003066
HumanPhenoStatus epilepticus without prominent motor symptoms

SCN1A SCN9A

9.52e-042792HP:0031475
HumanPhenoFocal aware seizure

SCN1A SCN9A

1.02e-032892HP:0002349
HumanPhenoLeft ventricular hypertrophy

CACNA1D SCN5A EPG5

1.06e-0312493HP:0001712
HumanPhenoStatus epilepticus with prominent motor symptoms

SCN1A SCN9A

1.10e-032992HP:0032658
HumanPhenoProgressive gait ataxia

SCN1A SCN9A

1.18e-033092HP:0007240
HumanPhenoProgressive ataxia

SCN1A SCN9A

1.18e-033092HP:0001329
HumanPhenoAbnormal autonomic nervous system physiology

SCN3A SCN5A SCN9A

1.22e-0313093HP:0012332
HumanPhenoEEG abnormality

SCN1A SCN3A EPG5 SCN8A SCN9A

1.23e-0354895HP:0002353
HumanPhenoSudden death

SCN1A SCN5A SCN8A

1.25e-0313193HP:0001699
HumanPhenoCogwheel rigidity

SCN1A SCN9A

1.34e-033292HP:0002396
HumanPhenoObsessive-compulsive trait

SCN1A SCN9A

1.42e-033392HP:0008770
HumanPhenoInterictal epileptiform activity

SCN1A SCN3A SCN8A SCN9A

1.48e-0331994HP:0011182
HumanPhenoAbnormality of temperature sensation

SCN1A SCN9A

1.51e-033492HP:0100772
HumanPhenoImpaired temperature sensation

SCN1A SCN9A

1.51e-033492HP:0010829
HumanPhenoCalcaneovalgus deformity

SCN1A SCN9A

1.51e-033492HP:0001848
HumanPhenoInterictal EEG abnormality

SCN1A SCN3A SCN8A SCN9A

1.59e-0332594HP:0025373
HumanPhenoDeformed tarsal bones

SCN1A SCN9A

1.60e-033592HP:0008119
HumanPhenoLimitation of knee mobility

SCN1A SCN9A

1.60e-033592HP:0010501
HumanPhenoLimitation of neck motion

SCN1A SCN9A

1.69e-033692HP:0005986
HumanPhenoDisturbance of facial expression

SCN1A SCN9A

1.69e-033692HP:0005324
HumanPhenoAbnormal neck physiology

SCN1A SCN9A

1.69e-033692HP:0025669
HumanPhenoGeneralized myoclonic seizure

SCN1A SCN8A SCN9A

1.78e-0314893HP:0002123
HumanPhenoHemiplegia

SCN1A SCN5A

1.99e-033992HP:0002301
HumanPhenoFocal non-motor seizure

SCN1A SCN8A

2.09e-034092HP:0032679
HumanPhenoCompulsive behaviors

SCN1A SCN8A SCN9A

2.14e-0315893HP:0000722
HumanPhenoAthetosis

CACNA1D SCN1A SCN8A

2.47e-0316693HP:0002305
HumanPhenoMyoclonus

SCN1A SCN3A SCN8A SCN9A

2.60e-0337194HP:0001336
HumanPhenoVentricular hypertrophy

CACNA1D SCN5A EPG5

2.73e-0317293HP:0001714
HumanPhenoAtypical absence seizure

SCN1A SCN9A

2.76e-034692HP:0007270
HumanPhenoGeneralized non-motor (absence) seizure

SCN1A SCN8A SCN9A

2.92e-0317693HP:0002121
HumanPhenoAbnormal hippocampus morphology

SCN1A SCN9A

3.00e-034892HP:0025100
HumanPhenoCerebral visual impairment

CACNA1D SCN1A SCN3A

3.07e-0317993HP:0100704
HumanPhenoAbnormal morphology of the limbic system

SCN1A SCN9A

3.13e-034992HP:0007343
HumanPhenoHypsarrhythmia

SCN1A SCN3A SCN8A

3.37e-0318593HP:0002521
HumanPhenoBilateral tonic-clonic seizure with focal onset

SCN1A SCN8A

3.51e-035292HP:0007334
HumanPhenoBilateral tonic-clonic seizure with generalized onset

SCN1A SCN9A

3.51e-035292HP:0025190
HumanPhenoEEG with multifocal slow activity

SCN3A SCN8A

3.51e-035292HP:0010844
MousePhenoabnormal action potential

CACNA1D HCN2 SCN1A SCN5A SCN8A SCN9A

4.36e-08133226MP:0005402
MousePhenofibrillation

CACNA1D SCN1A SCN5A

1.22e-0614223MP:0006109
MousePhenoirregular heartbeat

CACNA1D HCN2 SCN1A SCN5A

4.17e-0671224MP:0001636
MousePhenoabnormal spike wave discharge

HCN2 SCN1A SCN8A

6.70e-0624223MP:0008840
MousePhenoabnormal nervous system electrophysiology

CACNA1D HCN2 SCN1A SCN5A SCN8A SCN9A

8.81e-06329226MP:0002272
MousePhenoabsence seizures

HCN2 SCN1A SCN8A

2.14e-0535223MP:0003216
MousePhenononconvulsive seizures

HCN2 SCN1A SCN8A

3.22e-0540223MP:0000948
MousePhenoabnormal sinoatrial node conduction

CACNA1D HCN2 SCN5A

3.73e-0542223MP:0006142
MousePhenoventricular fibrillation

SCN1A SCN5A

4.94e-057222MP:0006110
MousePhenoatrial fibrillation

CACNA1D SCN5A

1.06e-0410222MP:0008543
MousePhenoseizures

HCN2 SCN1A SCN5A SCN8A SCN9A

2.02e-04360225MP:0002064
MousePhenosinus bradycardia

CACNA1D SCN5A

2.13e-0414222MP:0010637
MousePhenoabnormal seizure response to inducing agent

HCN2 SCN1A SCN8A SCN9A

2.48e-04201224MP:0009357
MousePhenostereotypic behavior

HCN2 SCN1A EPG5 SCN8A

3.15e-04214224MP:0001408
MousePhenoabnormal myocardial fiber physiology

CACNA1D SCN1A SCN5A

3.64e-0490223MP:0004215
MousePhenoventricular premature beat

SCN1A SCN5A

6.94e-0425222MP:0009732
MousePhenoheart block

CACNA1D SCN1A SCN5A

9.94e-04127223MP:0010559
DomainNa_channel_asu

SCN1A SCN3A SCN5A SCN7A SCN8A SCN9A

1.34e-1510286IPR001696
DomainNa_trans_assoc

SCN1A SCN3A SCN5A SCN7A SCN8A SCN9A

1.34e-1510286IPR010526
DomainNa_trans_assoc

SCN1A SCN3A SCN5A SCN7A SCN8A SCN9A

1.34e-1510286PF06512
DomainNa_trans_cytopl

SCN1A SCN3A SCN5A SCN8A SCN9A

3.11e-146285PF11933
DomainNa_trans_cytopl

SCN1A SCN3A SCN5A SCN8A SCN9A

3.11e-146285IPR024583
DomainChannel_four-helix_dom

CACNA1D SCN1A SCN3A SCN5A SCN7A SCN8A SCN9A

1.90e-1257287IPR027359
Domain-

CACNA1D SCN1A SCN3A SCN5A SCN7A SCN8A SCN9A

1.90e-12572871.20.120.350
DomainIon_trans_dom

CACNA1D HCN2 SCN1A SCN3A SCN5A SCN7A SCN8A SCN9A

4.22e-12114288IPR005821
DomainIon_trans

CACNA1D HCN2 SCN1A SCN3A SCN5A SCN7A SCN8A SCN9A

4.22e-12114288PF00520
DomainIQ

SCN1A SCN3A SCN5A SCN7A SCN8A SCN9A

1.92e-0981286SM00015
DomainIQ_motif_EF-hand-BS

SCN1A SCN3A SCN5A SCN7A SCN8A SCN9A

3.66e-0990286IPR000048
DomainIQ

SCN1A SCN3A SCN5A SCN8A SCN9A

2.47e-0793285PS50096
DomainIQ

SCN1A SCN3A SCN8A SCN9A

3.66e-0671284PF00612
DomainEF-hand-dom_pair

SCN1A SCN3A SCN7A SCN8A SCN9A

6.09e-05287285IPR011992
DomaincNMP-bd_CS

CNBD2 HCN2

2.57e-0416282IPR018488
DomainHelicase_C

DDX20 CHD6 EP400

5.40e-04107283PF00271
DomainHELICc

DDX20 CHD6 EP400

5.40e-04107283SM00490
DomainHelicase_C

DDX20 CHD6 EP400

5.54e-04108283IPR001650
DomainHELICASE_CTER

DDX20 CHD6 EP400

5.70e-04109283PS51194
DomainHELICASE_ATP_BIND_1

DDX20 CHD6 EP400

5.70e-04109283PS51192
DomainDEXDc

DDX20 CHD6 EP400

5.70e-04109283SM00487
DomainHelicase_ATP-bd

DDX20 CHD6 EP400

5.85e-04110283IPR014001
DomainCNMP_BINDING_1

CNBD2 HCN2

1.05e-0332282PS00888
DomainCNMP_BINDING_2

CNBD2 HCN2

1.05e-0332282PS00889
DomainSNF2_N

CHD6 EP400

1.05e-0332282PF00176
DomainSNF2_N

CHD6 EP400

1.05e-0332282IPR000330
DomaincNMP

CNBD2 HCN2

1.18e-0334282SM00100
DomaincNMP_binding

CNBD2 HCN2

1.18e-0334282PF00027
DomaincNMP-bd_dom

CNBD2 HCN2

1.25e-0335282IPR000595
DomainDNA/RNA_helicase_DEAH_CS

CHD6 EP400

1.25e-0335282IPR002464
DomainCNMP_BINDING_3

CNBD2 HCN2

1.25e-0335282PS50042
DomainDEAH_ATP_HELICASE

CHD6 EP400

1.47e-0338282PS00690
DomaincNMP-bd-like

CNBD2 HCN2

1.47e-0338282IPR018490
Domain-

CNBD2 HCN2

2.34e-03482822.60.120.10
DomainSANT

CHD6 EP400

2.54e-0350282SM00717
DomainRmlC-like_jellyroll

CNBD2 HCN2

2.64e-0351282IPR014710
DomainSANT/Myb

CHD6 EP400

2.74e-0352282IPR001005
PathwayREACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS

SCN1A SCN3A SCN5A SCN7A SCN8A SCN9A

3.59e-1231216M877
PathwayREACTOME_PHASE_0_RAPID_DEPOLARISATION

SCN1A SCN3A SCN5A SCN7A SCN8A SCN9A

4.41e-1232216M27455
PathwayREACTOME_L1CAM_INTERACTIONS

SCN1A SCN3A SCN5A SCN7A SCN8A SCN9A

1.72e-08121216M872
PathwayREACTOME_CARDIAC_CONDUCTION

SCN1A SCN3A SCN5A SCN7A SCN8A SCN9A

2.65e-08130216M27454
PathwayREACTOME_MUSCLE_CONTRACTION

SCN1A SCN3A SCN5A SCN7A SCN8A SCN9A

3.75e-07203216M5485
PathwayWP_DRAVET_SYNDROME

SCN1A SCN3A SCN8A

9.11e-0628213M45519
PathwayWP_ADHD_AND_AUTISM_ASD_PATHWAYS

SCN1A SCN3A SCN5A SCN7A SCN8A SCN9A

1.16e-05367216M48346
PathwayREACTOME_NERVOUS_SYSTEM_DEVELOPMENT

CACNA1D SCN1A SCN3A SCN5A SCN7A SCN8A SCN9A

1.28e-05575217M29853
PathwayWP_CHRONIC_HYPERGLYCEMIA_IMPAIRMENT_OF_NEURON_FUNCTION

SCN8A SCN9A

2.10e-0346212M46450
PathwayREACTOME_SENSORY_PERCEPTION_OF_TASTE

SCN3A SCN9A

2.19e-0347212M42524
PathwayWP_RETT_SYNDROME

SCN1A SCN8A

2.29e-0348212M39759
Pubmed

International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels.

SCN1A SCN3A SCN5A SCN8A SCN9A

2.91e-14928516382098
Pubmed

Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.

CACNA1D HCN2 SCN1A SCN3A SCN5A SCN7A SCN8A SCN9A

1.54e-1313928816985003
Pubmed

Regulation of neuronal voltage-gated sodium channels by the ubiquitin-protein ligases Nedd4 and Nedd4-2.

SCN1A SCN3A SCN5A SCN8A SCN9A

2.97e-131328515123669
Pubmed

Early development of electrical excitability in the mouse enteric nervous system.

SCN3A SCN5A SCN8A SCN9A

1.68e-12528422875929
Pubmed

A 'toothache tree' alkylamide inhibits Aδ mechanonociceptors to alleviate mechanical pain.

SCN1A SCN3A SCN8A SCN9A

5.03e-12628423652591
Pubmed

Expression pattern of neuronal and skeletal muscle voltage-gated Na+ channels in the developing mouse heart.

SCN1A SCN3A SCN5A SCN8A

4.22e-11928415746173
Pubmed

Nav1.2 haplodeficiency in excitatory neurons causes absence-like seizures in mice.

SCN1A SCN3A SCN5A SCN8A

1.66e-101228430175250
Pubmed

Mutations in the sodium channel genes SCN1A, SCN3A, and SCN9A in children with epilepsy with febrile seizures plus(EFS+).

SCN1A SCN3A SCN9A

4.67e-10328333895391
Pubmed

Nav1.1 localizes to axons of parvalbumin-positive inhibitory interneurons: a circuit basis for epileptic seizures in mice carrying an Scn1a gene mutation.

SCN1A SCN3A SCN8A

1.87e-09428317537961
Pubmed

Sodium channel expression and transcript variation in the developing brain of human, Rhesus monkey, and mouse.

SCN1A SCN3A SCN8A

1.87e-09428335031483
Pubmed

Abnormal changes in voltage-gated sodium channels subtypes NaV1.1, NaV1.2, NaV1.3, NaV1.6 and CaM/CaMKII pathway in low-grade astrocytoma.

SCN1A SCN3A SCN8A

1.87e-09428329578003
Pubmed

A new sodium channel alpha-subunit gene (Scn9a) from Schwann cells maps to the Scn1a, Scn2a, Scn3a cluster of mouse chromosome 2.

SCN1A SCN3A SCN9A

4.67e-0952838812438
Pubmed

Structure/function characterization of micro-conotoxin KIIIA, an analgesic, nearly irreversible blocker of mammalian neuronal sodium channels.

SCN3A SCN5A SCN8A

4.67e-09528317724025
Pubmed

Tyrosine-phosphorylated and nonphosphorylated sodium channel beta1 subunits are differentially localized in cardiac myocytes.

SCN1A SCN5A SCN8A

1.63e-08728315272007
Pubmed

Sodium channel Scn1b null mice exhibit prolonged QT and RR intervals.

SCN1A SCN5A SCN8A

3.91e-08928317884088
Pubmed

Confirmation of quantitative trait loci for alcohol preference in mice.

SCN1A SCN3A SCN7A

2.11e-07152839726281
Pubmed

Mutation in the neuronal voltage-gated sodium channel SCN1A in familial hemiplegic migraine.

SCN1A SCN5A

6.25e-07228216054936
Pubmed

Comparative structural analysis of human Nav1.1 and Nav1.5 reveals mutational hotspots for sodium channelopathies.

SCN1A SCN5A

6.25e-07228233712547
Pubmed

Reduction of Kcnt1 is therapeutic in mouse models of SCN1A and SCN8A epilepsy.

SCN1A SCN8A

6.25e-07228237901435
Pubmed

Aberrant regulation of a poison exon caused by a non-coding variant in a mouse model of Scn1a-associated epileptic encephalopathy.

SCN1A SCN8A

6.25e-07228233411788
Pubmed

An Scn1a epilepsy mutation in Scn8a alters seizure susceptibility and behavior.

SCN1A SCN8A

6.25e-07228226410685
Pubmed

Scn8a Antisense Oligonucleotide Is Protective in Mouse Models of SCN8A Encephalopathy and Dravet Syndrome.

SCN1A SCN8A

6.25e-07228231943325
Pubmed

Mapping of a FEB3 homologous febrile seizure locus on mouse chromosome 2 containing candidate genes Scn1a and Scn3a.

SCN1A SCN3A

6.25e-07228227690330
Pubmed

Sinus node dysfunction following targeted disruption of the murine cardiac sodium channel gene Scn5a.

CACNA1D SCN5A

6.25e-07228215932895
Pubmed

Kinetic Analysis of Membrane Potential Dye Response to NaV1.7 Channel Activation Identifies Antagonists with Pharmacological Selectivity against NaV1.5.

SCN5A SCN9A

6.25e-07228226861708
Pubmed

Sodium channel slow inactivation interferes with open channel block.

SCN8A SCN9A

6.25e-07228227174182
Pubmed

Correlations in timing of sodium channel expression, epilepsy, and sudden death in Dravet syndrome.

SCN1A SCN3A

6.25e-07228223965409
Pubmed

Electrophysiological Differences between the Same Pore Region Mutation in SCN1A and SCN3A.

SCN1A SCN3A

6.25e-07228224990319
Pubmed

Na+ current properties in islet α- and β-cells reflect cell-specific Scn3a and Scn9a expression.

SCN3A SCN9A

6.25e-07228225172946
Pubmed

Persistent Nav1.1 and Nav1.6 currents drive spinal locomotor functions through nonlinear dynamics.

SCN1A SCN8A

6.25e-07228237665666
Pubmed

The voltage-gated sodium channel Scn8a is a genetic modifier of severe myoclonic epilepsy of infancy.

SCN1A SCN8A

6.25e-07228217881658
Pubmed

Role of the hippocampus in Nav1.6 (Scn8a) mediated seizure resistance.

SCN1A SCN8A

1.87e-06328224704313
Pubmed

Voltage-gated sodium channels in taste bud cells.

SCN3A SCN9A

1.87e-06328219284629
Pubmed

Sodium channels SCN1A, SCN2A and SCN3A in familial autism.

SCN1A SCN3A

1.87e-06328212610651
Pubmed

The sorting receptor Rer1 controls Purkinje cell function via voltage gated sodium channels.

SCN1A SCN8A

1.87e-06328228117367
Pubmed

Reduced sodium current in Purkinje neurons from Nav1.1 mutant mice: implications for ataxia in severe myoclonic epilepsy in infancy.

SCN1A SCN8A

1.87e-06328217928448
Pubmed

SCN1A, SCN2A and SCN3A gene polymorphisms and responsiveness to antiepileptic drugs: a multicenter cohort study and meta-analysis.

SCN1A SCN3A

1.87e-06328223859570
Pubmed

Abnormal expression of voltage-gated sodium channels Nav1.7, Nav1.3 and Nav1.8 in trigeminal neuralgia.

SCN3A SCN9A

1.87e-06328219699781
Pubmed

Early expression of sodium channel transcripts and sodium current by cajal-retzius cells in the preplate of the embryonic mouse neocortex.

SCN1A SCN3A

1.87e-06328214973256
Pubmed

Multidrug resistance in epilepsy and polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, and SCN3A: correlation among phenotype, genotype, and mRNA expression.

SCN1A SCN3A

1.87e-06328218784617
Pubmed

Characterization of 5' untranslated regions of the voltage-gated sodium channels SCN1A, SCN2A, and SCN3A and identification of cis-conserved noncoding sequences.

SCN1A SCN3A

1.87e-06328217544618
Pubmed

Inhibition of G protein-gated K+ channels by tertiapin-Q rescues sinus node dysfunction and atrioventricular conduction in mouse models of primary bradycardia.

CACNA1D SCN5A

1.87e-06328232555258
Pubmed

Human Nav1.6 Channels Generate Larger Resurgent Currents than Human Nav1.1 Channels, but the Navβ4 Peptide Does Not Protect Either Isoform from Use-Dependent Reduction.

SCN1A SCN8A

1.87e-06328226182346
Pubmed

Variable patterns of mutation density among NaV1.1, NaV1.2 and NaV1.6 point to channel-specific functional differences associated with childhood epilepsy.

SCN1A SCN8A

1.87e-06328232845893
Pubmed

De novo SCN1A, SCN8A, and CLCN2 mutations in childhood absence epilepsy.

SCN1A SCN8A

1.87e-06328231054517
Pubmed

Human voltage-gated sodium channel mutations that cause inherited neuronal and muscle channelopathies increase resurgent sodium currents.

SCN5A SCN9A

1.87e-06328220038812
Pubmed

Comparison and optimization of in silico algorithms for predicting the pathogenicity of sodium channel variants in epilepsy.

SCN1A SCN8A

1.87e-06328228518218
Pubmed

GAPDH-mediated posttranscriptional regulations of sodium channel Scn1a and Scn3a genes under seizure and ketogenic diet conditions.

SCN1A SCN3A

1.87e-06328227816501
Pubmed

Expression of alternatively spliced sodium channel alpha-subunit genes. Unique splicing patterns are observed in dorsal root ganglia.

SCN8A SCN9A

1.87e-06328215302875
Pubmed

Evolution and diversity of mammalian sodium channel genes.

SCN7A SCN9A

3.75e-06428210198179
Pubmed

Neuronal voltage-gated ion channels are genetic modifiers of generalized epilepsy with febrile seizures plus.

SCN1A SCN8A

3.75e-06428221156207
Pubmed

Models for discovery of targeted therapy in genetic epileptic encephalopathies.

SCN1A SCN8A

3.75e-06428228742937
Pubmed

Association of sodium voltage-gated channel genes polymorphisms with epilepsy risk and prognosis in the Saudi population.

SCN1A SCN3A

3.75e-06428235801810
Pubmed

Dorsal root ganglia isolated from Nf1+/- mice exhibit increased levels of mRNA expression of voltage-dependent sodium channels.

SCN1A SCN9A

3.75e-06428222260870
Pubmed

Use of recombinant inbred strains for studying genetic determinants of responses to alcohol.

SCN1A SCN3A

3.75e-0642828974318
Pubmed

Molecular determinants of voltage-gated sodium channel regulation by the Nedd4/Nedd4-like proteins.

SCN3A SCN5A

6.24e-06528215548568
Pubmed

Three brain sodium channel alpha-subunit genes are clustered on the proximal segment of mouse chromosome 2.

SCN1A SCN3A

6.24e-0652821679748
Pubmed

Case-control association study of polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, SCN3A, SCN1B, and SCN2B and epilepsy.

SCN1A SCN3A

6.24e-06528224337656
Pubmed

Contactin regulates the current density and axonal expression of tetrodotoxin-resistant but not tetrodotoxin-sensitive sodium channels in DRG neurons.

SCN8A SCN9A

9.36e-06628216029194
Pubmed

An animal model of oxaliplatin-induced cold allodynia reveals a crucial role for Nav1.6 in peripheral pain pathways.

SCN3A SCN8A

9.36e-06628223711479
Pubmed

Organization, sequence, chromosomal localization, and promoter identification of the mouse orphan nuclear receptor Nurr1 gene.

SCN3A SCN9A

9.36e-0662829143501
Pubmed

Pain without nociceptors? Nav1.7-independent pain mechanisms.

SCN3A SCN9A

1.31e-05728224440715
Pubmed

Diagnostic yield of genetic testing in epileptic encephalopathy in childhood.

SCN1A SCN8A

1.31e-05728225818041
Pubmed

Significant determinants of mouse pain behaviour.

SCN3A SCN9A

1.74e-05828225101983
Pubmed

Interaction of muscle and brain sodium channels with multiple members of the syntrophin family of dystrophin-associated proteins.

SCN1A SCN5A

1.74e-0582829412493
Pubmed

Genetic mapping of the peripheral sodium channel genes, Scn9a and Scn10a, in the mouse.

SCN3A SCN9A

2.24e-0592828854872
Pubmed

Intersubspecific subcongenic mouse strain analysis reveals closely linked QTLs with opposite effects on body weight.

SCN7A SCN9A

2.80e-051028221451961
Pubmed

Quantitative trait loci mapping of genes that influence the sensitivity and tolerance to ethanol-induced hypothermia in BXD recombinant inbred mice.

SCN1A SCN3A

4.10e-05122828169823
Pubmed

A high-density association screen of 155 ion transport genes for involvement with common migraine.

SCN5A SCN9A

4.10e-051228218676988
Pubmed

Pacsin 2 is required for the maintenance of a normal cardiac function in the developing mouse heart.

HCN2 SCN5A

5.65e-051428229107716
Pubmed

GATA6 is a regulator of sinus node development and heart rhythm.

CACNA1D SCN5A

1.18e-042028233443158
Pubmed

Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates.

ATP13A5 ELOVL6 TOP2A SCN1A

2.24e-0437628424154525
Pubmed

Tbx3 controls the sinoatrial node gene program and imposes pacemaker function on the atria.

HCN2 SCN5A

2.86e-043128217473172
Pubmed

Identification of new ciliary signaling pathways in the brain and insights into neurological disorders.

HCN2 SLC30A1 SCN1A SCN9A

2.97e-0440528438187761
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

CHD6 EP400 MFAP3L EPG5

3.03e-0440728412693553
Pubmed

Integrated Transcriptome and Network Analysis Reveals Spatiotemporal Dynamics of Calvarial Suturogenesis.

LGR5 TOP2A

3.25e-043328232640236
Pubmed

The splicing regulator Rbfox2 is required for both cerebellar development and mature motor function.

CACNA1D SCN8A

3.25e-043328222357600
Pubmed

Oncogenic ZMYND11-MBTD1 fusion protein anchors the NuA4/TIP60 histone acetyltransferase complex to the coding region of active genes.

EP400 TOP2A

5.28e-044228235705031
Pubmed

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.

DDX20 CHD6 SCN8A SCN9A

5.42e-0447528431040226
Pubmed

Aire's partners in the molecular control of immunological tolerance.

CHD6 TOP2A

6.06e-044528220085707
Pubmed

Defects During Mecp2 Null Embryonic Cortex Development Precede the Onset of Overt Neurological Symptoms.

CACNA1D SCN8A

6.06e-044528225979088
Pubmed

Large-scale identification of c-MYC-associated proteins using a combined TAP/MudPIT approach.

DDX20 EP400 TOP2A

6.45e-0421128317314511
InteractionSCN11A interactions

CACNA1D SCN1A SCN5A SCN8A SCN9A

8.68e-1215275int:SCN11A
InteractionNALCN interactions

CACNA1D SCN1A SCN5A SCN9A

2.53e-0914274int:NALCN
InteractionSCN5A interactions

CACNA1D SCN1A SCN5A SCN8A SCN9A

4.30e-0947275int:SCN5A
InteractionSCN9A interactions

CACNA1D SCN1A SCN5A SCN9A

1.51e-0821274int:SCN9A
InteractionCACNA1D interactions

CACNA1D SCN1A SCN5A SCN9A

2.66e-0824274int:CACNA1D
InteractionSCN1A interactions

CACNA1D SCN1A SCN5A SCN9A

5.93e-0829274int:SCN1A
InteractionCACNA1B interactions

CACNA1D SCN1A SCN5A SCN9A

1.64e-0737274int:CACNA1B
InteractionSCN10A interactions

CACNA1D SCN1A SCN5A

3.51e-0711273int:SCN10A
InteractionCACNA1C interactions

CACNA1D SCN1A SCN5A SCN9A

1.27e-0661274int:CACNA1C
InteractionCACNA1A interactions

CACNA1D SCN1A SCN5A SCN9A

2.08e-05123274int:CACNA1A
InteractionFGF14 interactions

DDX20 SCN5A SCN8A

2.38e-0542273int:FGF14
InteractionSCN4B interactions

SCN1A SCN8A

4.82e-058272int:SCN4B
InteractionNEDD4L interactions

SCN1A SCN3A SCN5A SCN8A SCN9A

5.93e-05320275int:NEDD4L
InteractionSCN8A interactions

SCN5A SCN8A

3.24e-0420272int:SCN8A
CytobandEnsembl 112 genes in cytogenetic band chr2q24

SCN1A SCN3A SCN7A SCN9A

1.09e-06127284chr2q24
Cytoband2q24

SCN3A SCN9A

1.97e-05112822q24
Cytoband19p13.3

HCN2 TMEM259

9.18e-0323728219p13.3
CytobandEnsembl 112 genes in cytogenetic band chr20q11

CNBD2 TM9SF4

1.00e-02248282chr20q11
GeneFamilySodium voltage-gated channel alpha subunits

SCN1A SCN3A SCN5A SCN8A SCN9A

1.59e-1392151203
GeneFamilyGATA zinc finger domain containing|Myb/SANT domain containing

CHD6 EP400

1.71e-0353212532
ToppCellPND03-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ATP13A5 SCN1A SCN3A SCN5A

3.33e-06165284347b59aa625a8a960828b8620824d8ac48990e07
ToppCellPND03-Endothelial-Endothelial_lymphatic|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ATP13A5 SCN1A SCN3A SCN5A

3.33e-061652841890f9c33b0c5b381d57f97042da2610a093a6de
ToppCellPND03-Endothelial-Endothelial_lymphatic-Lymphatic_EC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ATP13A5 SCN1A SCN3A SCN5A

3.33e-06165284507c89ece0a336b8e9c65b79889a714e17ddca27
ToppCellPND03-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ATP13A5 SCN1A SCN3A SCN5A

3.33e-0616528439a25be081a5d59c7cf107a997d352793d5025fb
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CACNA1D DEPDC1B SCN3A SCN7A

4.60e-06179284666072c0e8448dbaec1683d18368ec2502453f90
ToppCellImmune_cells-large_pre-B.|World / Lineage and Cell class

ELOVL6 LGR5 TOP2A EPG5

5.02e-0618328481b5ed6ed661d2d6a9b807fefd2f0d59bd4ea77e
ToppCelldroplet-Heart-4Chambers-21m-Endothelial-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CNBD2 SCN3A MFAP3L SCN5A

5.24e-06185284bb5a4cf93534b9bcd0923f314c389d571e91e7f8
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2-D175|Adult / Lineage, Cell type, age group and donor

CACNA1D MAP3K13 SCN1A SCN9A

5.59e-06188284ec38def1fdbb34ed9b30244806975bd5a4370164
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CACNA1D DEPDC1B SCN3A SCN7A

5.71e-061892847eb8f5a951e80f1cfac4d7c9eb169f4eb100c917
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CACNA1D DEPDC1B SCN3A SCN7A

5.71e-06189284975c0f079903ae36b0ffa54e86294d42ec7697de
ToppCellSomatosensory_Cortex_(S1)-Neuronal|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1D SCN1A SCN3A SCN8A

6.86e-06198284c01091ef18e096d792ea2a7a715764a5b215355f
ToppCellprimary_auditory_cortex_(A1C)-Neuronal|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1D SCN1A SCN3A SCN8A

6.86e-061982846d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1D SCN1A SCN3A SCN8A

6.86e-061982844ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCellMacroglial-Polydendrocytes-PDGFRA---|Macroglial / cells hierarchy compared to all cells using T-Statistic

CACNA1D SCN1A SCN3A SCN9A

7.14e-062002844fc3de4bff7ed2bf40b38462c4b4e9b87af6a4ca
ToppCellMacroglial-Polydendrocytes-PDGFRA-|Macroglial / cells hierarchy compared to all cells using T-Statistic

CACNA1D SCN1A SCN3A SCN9A

7.14e-06200284f17b5a54e8f9eba9dcd0808ba4e8d275ac41bce2
ToppCellMacroglial-Polydendrocytes-PDGFRA--|Macroglial / cells hierarchy compared to all cells using T-Statistic

CACNA1D SCN1A SCN3A SCN9A

7.14e-06200284cc3409518f8b436ea92deb955e81114b3f410ff7
ToppCellMacroglial-Polydendrocytes-PDGFRA----L1-6|Macroglial / cells hierarchy compared to all cells using T-Statistic

CACNA1D SCN1A SCN3A SCN9A

7.14e-06200284310cd53db1c137f6af74e6ae682221d7ac27310c
ToppCellMacroglial-Polydendrocytes-PDGFRA|Macroglial / cells hierarchy compared to all cells using T-Statistic

CACNA1D SCN1A SCN3A SCN9A

7.14e-06200284c24a3099e3d96d8b72f6d05286bb355d661a0377
ToppCellMacroglial-Polydendrocytes|Macroglial / cells hierarchy compared to all cells using T-Statistic

CACNA1D SCN1A SCN3A SCN9A

7.14e-06200284961858738ce35db8760c8c2e136f8369bc444ccf
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Synpr|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

SCN5A SCN7A SCN9A

8.93e-05139283408bc31aa5e1c2b379f79198fe8b5411f8d7bd08
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CACNA1D DEPDC1B SCN7A

9.12e-051402835e81fa3a19d23f0e9cae3878431ca1f78dff7238
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP13A5 SCN1A SCN9A

1.01e-0414528396712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCellTCGA-Thymus-Primary_Tumor-Thymoma-Type_AB-8|TCGA-Thymus / Sample_Type by Project: Shred V9

LGR5 SCN1A SCN7A

1.14e-041512835906562efd36fbcb91f96e0a0d3a8fe999ba1e79
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DEPDC1B SCN1A SCN7A

1.14e-04151283f41c6558a5874b6464c157027fdf202257c60e5b
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DEPDC1B TOP2A SCN5A

1.26e-04156283955547dfeb1b1ad4957b4338701055726b22619f
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CACNA1D DEPDC1B SCN7A

1.26e-041562834d2679e7639758c49fc25a2deb9109b08f0a3e57
ToppCellPND07-Endothelial-Endothelial_lymphatic|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SCN1A SCN3A SCN5A

1.38e-04161283133b4fadb499e842c19f573f9cf09ce08c1d4813
ToppCellPND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SCN1A SCN3A SCN5A

1.38e-04161283cb177ca10d848d0e25399ab5ebfcde1071fb94c2
ToppCellPND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SCN1A SCN3A SCN5A

1.38e-041612839466b8658244116f8d21f2f88fb8c2d184b1bdf2
ToppCellPND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SCN1A SCN3A SCN5A

1.41e-0416228396c6e94a10b124a1d25dcd705ec5aaa8609c1089
ToppCellPND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ELOVL6 DEPDC1B TOP2A

1.46e-04164283ae09e5aabd1347b865474255e7411c04f63efb3b
ToppCell367C-Myeloid-Dendritic-cDC_proliferating_2|367C / Donor, Lineage, Cell class and subclass (all cells)

DEPDC1B TOP2A SCN9A

1.46e-041642830662cd9d21608efacc336e0a582859f3b9a4951d
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|356C / Donor, Lineage, Cell class and subclass (all cells)

MAP3K13 ELOVL6 EPG5

1.51e-04166283c4f7ea1cad962b1d6ad77423d15978b68a0d6f1d
ToppCell10x_3'_v2v3-Neoplastic-Stem-like-OPC-like-OPC-like_Prolif-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

DDX20 TOP2A SCN8A

1.59e-041692832833a8a7094e4d407eb923f2bc59b9b112c6bae4
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP13A5 SCN3A SCN9A

1.59e-0416928312bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell343B-Lymphocytic-CD4_T-cell-Proliferating_T_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

CACNA1D DEPDC1B TOP2A

1.65e-041712834ccd88cf812dd8bfdc55159c6f504e9c84e4f4fc
ToppCell367C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

DDX20 DEPDC1B TOP2A

1.65e-0417128352fdc2a4ec36fb91583b1215362548ceb6740ae1
ToppCell367C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

DDX20 DEPDC1B TOP2A

1.65e-04171283e3cab55f39879e2bd3e8bda91802181075839bc4
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

MAP3K13 ELOVL6 EPG5

1.68e-04172283a9e13aa36087170dadca421ba9de588e5a1cf715
ToppCellASK440-Epithelial-Transformed_epithelium|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

SLC30A1 MFAP3L SELENOO

1.68e-04172283df3800bcd9777d02900eba0cfc26ab73de8a1d95
ToppCell367C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-|367C / Donor, Lineage, Cell class and subclass (all cells)

DEPDC1B TOP2A SCN1A

1.68e-04172283a9e65201ad9ab4f64251aba2c0bb3d8f9e0193b6
ToppCell367C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)|367C / Donor, Lineage, Cell class and subclass (all cells)

DEPDC1B TOP2A SCN1A

1.68e-0417228326006967d0c82f7bd9b36a18e97a1b93e856aa67
ToppCelldroplet-Lung-1m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-proliferating_NK|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HCN2 DEPDC1B TOP2A

1.71e-04173283c399786aa25bdbe3394988db6955842b5b7e6b41
ToppCellIonocyte-iono-2|World / Class top

CACNA1D SLC30A1 SCN3A

1.71e-04173283e5ec28ccc5e048fd98de4c876e5c53b866b66228
ToppCelldroplet-Lung-LUNG-1m-Lymphocytic-Proliferating_NK|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HCN2 DEPDC1B TOP2A

1.71e-0417328331784679190fbd95fc23d7c66008eb21b8c7cc5d
ToppCellBronchial_Brush-Epithelial-Ionocytes|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

SCN3A SCN7A SCN9A

1.71e-04173283e1de849dcd96063136bdac87e050ddbd55cabdcc
ToppCellCOVID-19-Heart-Neuronal|Heart / Disease (COVID-19 only), tissue and cell type

MFAP3L SCN7A SCN9A

1.71e-041732836fb5f9e6536a5d57fd8e6657b494047a2d0bc9c7
ToppCell10x5'-bone_marrow-Hematopoietic_progenitors-Progenitor_Myeloid|bone_marrow / Manually curated celltypes from each tissue

LGR5 DEPDC1B TOP2A

1.71e-041732835645a3b1e805c71d5d65fc8e4edc4e13208063fc
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_FAM150B|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LGR5 SCN7A SCN9A

1.73e-04174283cc4c7f00a25a7814b52d4599166615daa140cc31
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

MAP3K13 ELOVL6 EPG5

1.76e-04175283f3a68aeb79c4935006e17a5ff3445a8ec0e33f5f
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Degenerative_Distal_Convoluted_Tubule_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DEPDC1B SCN3A SCN7A

1.76e-04175283787ac1a12cda10af5c8830471702a4cbaf43e79e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DEPDC1B TOP2A SCN3A

1.76e-04175283876cea684faf42ff3eb4623ad6d7a1fb1276ee02
ToppCellTCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Follicular-7|TCGA-Thryoid / Sample_Type by Project: Shred V9

CNBD2 HCN2 MFAP3L

1.79e-041762839a4cef3dc88f64a71b91ab4790ea19334afee3ee
ToppCellpdx-Tumor_cells-T2|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

CACNA1D MAP3K13 LGR5

1.79e-041762831e21f80cf0e695ffdd63e4a72cf1e3fa41b60341
ToppCellfacs-Heart-RV-18m-Lymphocytic-T_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DEPDC1B TOP2A SCN1A

1.79e-041762833e7647364c13beade9ca278c7ce8e89546e0b060
ToppCellfacs-Heart-RV-18m-Lymphocytic-T_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DEPDC1B TOP2A SCN1A

1.79e-04176283a55572470de6af6cbf29ed4f785fdca62d24cd23
ToppCellNS-moderate-d_0-4-Lymphoid-NKT-proliferating|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DEPDC1B TOP2A SCN8A

1.82e-04177283174c54acfe19e2bb31418d69e228032ba724cbb6
ToppCellwk_15-18-Epithelial-PNS-Schwann_precursor|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

SCN1A SCN5A SCN8A

1.82e-041772835357359e6c2161a37f39a6b3b78449f5cbc327d1
ToppCell3'-Adult-Appendix-Epithelial-epithelial_progenitor_cell-Stem_cells|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DDX20 CNBD2 LGR5

1.82e-0417728334458f1eb7f3b1fd0cb9904529c01a9ca2f15500
ToppCellILEUM-inflamed-(9)_Enteric_neurons|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

MFAP3L SCN7A SCN9A

1.85e-04178283d9142151819afb0dc22bfb32a9c9dba5f553067d
ToppCellILEUM-inflamed-(9)_Neuro_cell|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

MFAP3L SCN7A SCN9A

1.85e-04178283611504b0a9e6318b18fba83787b03f9245c82252
ToppCellPCW_13-14-Neuronal-Neuronal_postreplicative-neuro_neuronal_(6)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

HCN2 SCN1A SCN3A

1.89e-04179283af0b54c9ea0b6e4210f22dbb6e88ecd3276a5f86
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DEPDC1B TOP2A SCN3A

1.92e-04180283401df9cddcbca1eb8f0d2687bcacd98e95dc1493
ToppCellPND01-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DEPDC1B TOP2A SCN7A

1.92e-04180283b35a8c6169f4b548b912af005e92ae7c6596f376
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_FAM150B|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LGR5 SCN7A SCN9A

1.95e-04181283af92b8b7f455210dab502ef6964f3a0162180759
ToppCelldroplet-Thymus-nan-24m-Lymphocytic-DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DEPDC1B TOP2A SCN5A

1.95e-041812833fe648db1cb8326066d8bde3ca1287c5c9af19bd
ToppCellnormal_Lung-Myeloid_cells-CD207+CD1a+_LCs|Myeloid_cells / Location, Cell class and cell subclass

CACNA1D SCN3A SCN7A

1.98e-041822838dd79fef8f8463ad3194f9cc07c6cacf2c886304
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DEPDC1B SCN3A SCN7A

1.98e-041822835f513bbb7125956eb528e3120de3fd776770a7c3
ToppCell3'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PPP1R37 DEPDC1B TOP2A

1.98e-04182283007fa56ed8b91f9af0df2114c00410b2f6cec8b6
ToppCell3'-GW_trimst-1.5-SmallIntestine-Epithelial-epithelial_progenitor_cell-TA|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LGR5 DEPDC1B TOP2A

2.01e-041832830d21befacefc6c597e7b501ed41b7fe9385a78df
ToppCellPBMC-Control-Myeloid-Neutrophil-immature_Neutrophil|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TOP2A MFAP3L SELENOO

2.04e-04184283a8c6028d745aaa6ee7842259238694cb50ce0526
ToppCellPBMC-Control-Myeloid-Neutrophil-immature_Neutrophil-Neu_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TOP2A MFAP3L SELENOO

2.04e-04184283081d045f3bc98a36f342de7d50f39c9a888dd7eb
ToppCellControl-Myeloid_G-immature_Neutrophil|Control / Disease group, lineage and cell class

TOP2A MFAP3L SELENOO

2.04e-0418428345f873236f7e90fb78c8e291d3b5b92d121acec9
ToppCellPBMC-Control-Myeloid-Neutrophil-immature_Neutrophil|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

TOP2A MFAP3L SELENOO

2.04e-0418428384c20730cd92b9aaa50077d7b625e37e7f9e91d2
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_FAM150B|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LGR5 SCN7A SCN9A

2.04e-041842837d41784eac0935e77d6bc701f20c693adf998730
ToppCellControl-immature_Neutrophil-|Control / Disease condition and Cell class

TOP2A MFAP3L SELENOO

2.04e-04184283c4e8ba82a6aa76c46f05a71d5f1c7926555318cf
ToppCellControl-immature_Neutrophil|Control / Disease condition and Cell class

TOP2A MFAP3L SELENOO

2.04e-041842832fdae5c6b3eb2232881d933a8c1061fda3623016
ToppCelldroplet-Spleen-nan-24m-Lymphocytic-immature_NKT_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HCN2 DEPDC1B TOP2A

2.04e-04184283b998803180322a5ea2b567928dea531c26816c3c
ToppCellPBMC-Control-Myeloid-Neutrophil-immature_Neutrophil-Neu_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

TOP2A MFAP3L SELENOO

2.04e-04184283d31d4116d1d196633784863781fa45673607a421
ToppCellURO-Lymphocyte-T_NK-T_NK_proliferative|URO / Disease, Lineage and Cell Type

DEPDC1B TOP2A SCN5A

2.08e-041852830ae9c646679c69a553eda670aef0e0495feb0286
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L3-4_RORB_RPS3P6|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MFAP3L SCN7A SCN9A

2.08e-0418528310da5c2a92bfb3248d3f6f94a0933996326cf590
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DEPDC1B SCN3A SCN7A

2.14e-04187283f124d2c699b717b7c02a1a70493f515b83dc2f4c
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CACNA1D DEPDC1B SCN3A

2.18e-04188283eec3d353e51358db4c7621265ee0fdd4298e5b0e
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-epithelial_progenitor_cell-TA|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LGR5 DEPDC1B TOP2A

2.18e-04188283b3cae49f0665ace0016a6441cbf9ae40755b0ea3
ToppCellCOVID-19-kidney-DCT|COVID-19 / Disease (COVID-19 only), tissue and cell type

CACNA1D DEPDC1B SCN3A

2.18e-041882831d56cd409793f05cca20757ab26e91f1a1ee67b5
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CACNA1D DEPDC1B SCN3A

2.18e-04188283bc089cd73d283ed7d2ecbb3936673b4edc89f666
ToppCellCOVID-19-kidney-DCT|kidney / Disease (COVID-19 only), tissue and cell type

CACNA1D DEPDC1B SCN3A

2.18e-04188283df1fd0819d301679f3c9ea404e942e39095912eb
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DEPDC1B SCN3A SCN7A

2.21e-04189283e32172ad09e93f6ac6ea2b92145b2b73003f7970
ToppCellNeuroendocrine-neuroendo-2-Calca|World / Class top

SCN3A SCN8A SCN9A

2.21e-041892836baa9a74560121cc008bb8fa9b2b7a335b3aeee0
ToppCellInt-URO-Lymphocyte-T_NK-T_NK_proliferative|Int-URO / Disease, Lineage and Cell Type

DEPDC1B TOP2A SCN8A

2.25e-04190283005967c540418b85311308072a07c684f4296aef
ToppCellRV-08._Macrophage|World / Chamber and Cluster_Paper

DEPDC1B TOP2A SCN9A

2.32e-04192283a1b5dc5beb97a23729b97b54fb4574d10d8fbfb3
ToppCellNeuroendocrine|World / Class top

SCN3A SCN8A SCN9A

2.32e-041922830199da3ef9ddb6673e9aa41f346f374838aec182
ToppCell5'-Adult-SmallIntestine-Epithelial-mature_enterocytic-Paneth|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1D LGR5 TOP2A

2.39e-041942832f6e62a4ec8707bd5a16c0734c5131af55207ea2
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-Neuronal-midbrain/hindbrain_cells|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

MAP3K13 SCN3A SCN9A

2.46e-041962830767581b69bc7e6334d580ca02ed1e831b7b55da
ToppCellMid-temporal_gyrus_(MTG)-Neuronal|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1D SCN3A SCN8A

2.46e-04196283676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CACNA1D DEPDC1B SCN7A

2.46e-04196283f40d10ea7714067585493fdc89744714aa427de8
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Degenerative_Distal_Convoluted_Tubule_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CACNA1D DEPDC1B SCN7A

2.46e-04196283b8350340d86e4524e9616a427e7f2e116a6fb3be
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CACNA1D LGR5 SCN7A

2.50e-0419728344673c38384453207871d3fd8e8ba9093cc06bc5
ToppCell5'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature-cycling_ENCC/glia|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DEPDC1B TOP2A SCN5A

2.50e-04197283cd7e34318b4ae72b7b312fda8cc0e041c2ac4ab5
ToppCellTransverse-T_cell-cycling_gd_T|Transverse / Region, Cell class and subclass

DEPDC1B TOP2A SCN5A

2.54e-041982835131b0b7d6c4dd8872cef9f2e233f59f751b4690
DrugZonisamide

SCN1A SCN3A SCN5A SCN9A

4.31e-0917284DB00909
DrugAC1L1MOZ

SCN3A SCN5A SCN7A SCN9A

3.15e-0827284CID000031958
Drugtocainide

SCN3A SCN5A SCN7A SCN9A

4.90e-0830284CID000038945
DrugTetrodotoxin

SCN3A SCN5A SCN8A SCN9A

1.62e-0740284ctd:D013779
Druglamotrigine

CACNA1D SCN3A SCN5A SCN7A SCN9A

2.82e-07116285CID000003878
Drugpilsicainide

SCN3A SCN5A SCN7A SCN9A

2.88e-0746284CID000004820
Drugbepridil

CACNA1D SCN3A SCN5A SCN7A SCN9A

4.25e-07126285CID000002351
DrugAC1L1CQC

SCN3A SCN5A SCN7A SCN9A

1.18e-0665284CID000002012
Drugmexiletine

SCN3A SCN5A SCN7A SCN9A

1.25e-0666284CID000004178
Drugdisopyramide

SCN3A SCN5A SCN7A SCN9A

1.25e-0666284CID000003114
Drugdibucaine

SCN3A SCN5A SCN7A SCN9A

1.41e-0668284CID000003025
DrugRanolazine

SCN5A SCN9A

1.46e-062282DB00243
DrugPhenytoin

SCN1A SCN5A

1.46e-062282DB00252
Drugdiprafenone

SCN3A SCN7A SCN9A

1.59e-0619283CID000071249
Drugflecainide

SCN3A SCN5A SCN7A SCN9A

1.68e-0671284CID000003355
Druggabapentin

CACNA1D SCN3A SCN5A SCN7A SCN9A

1.82e-06169285CID000003446
Drugriluzole

CACNA1D SCN3A SCN5A SCN7A SCN9A

2.10e-06174285CID000005070
DrugNSC7524

CACNA1D SCN3A SCN5A SCN7A SCN9A

2.62e-06182285CID000005657
DrugSodium

SCN3A SCN5A SCN8A SCN9A

3.30e-0684284ctd:D012964
DrugAC1NT1AF

SCN3A SCN7A SCN9A

3.76e-0625283CID005322157
DrugPirmenolum

SCN3A SCN7A SCN9A

4.25e-0626283CID000004853
DrugN-(2-methyl-3-(4-(4-(4-(trifluoromethoxy)benzyloxy)piperidin-1-yl)-1,3,5-triazin-2-ylamino)phenyl)acetamide

SCN3A SCN9A

4.37e-063282ctd:C561228
Drugnefopam

SCN3A SCN7A SCN9A

4.78e-0627283CID000004450
DrugPbTx-1

SCN3A SCN7A SCN9A

4.78e-0627283CID006437089
Drugparaben

SCN3A SCN7A SCN9A

5.35e-0628283CID000007175
Drugpropafenone

SCN3A SCN5A SCN7A SCN9A

6.10e-0698284CID000004932
Drugquindine

HCN2 SCN3A SCN5A SCN7A SCN9A

6.45e-06219285CID000001065
Drugphenytoin

CACNA1D SCN3A SCN5A SCN7A SCN9A

6.45e-06219285CID000001775
Drugisradipine

CACNA1D SCN3A SCN7A SCN9A

6.61e-06100284CID000003784
DrugNSC93767

SCN3A SCN7A SCN9A

8.07e-0632283CID000005658
Drugpyraclofos

CACNA1D SCN5A SCN7A SCN9A

8.34e-06106284CID000093460
DrugLidocaine

SCN5A SCN9A

8.74e-064282DB00281
Drug5-hydroxypropafenone

SCN3A SCN7A SCN9A

9.72e-0634283CID000107927
Drugtetradotoxin

CACNA1D SCN3A SCN5A SCN7A SCN8A SCN9A

1.13e-05428286CID000020382
Drugbenzocaine

SCN3A SCN7A SCN9A

1.26e-0537283CID000002337
Drugaprindine

SCN3A SCN7A SCN9A

1.37e-0538283CID000002218
DrugS-ropivacaine

SCN3A SCN7A SCN9A

1.60e-0540283CID000071273
DrugAPETx1, Anthopleura elegantissima

SCN3A SCN8A

2.18e-056282ctd:C475726
Drugspiradoline

SCN3A SCN7A SCN9A

2.44e-0546283CID000005620
Drugindoxacarb

SCN3A SCN7A SCN9A

2.95e-0549283CID000107720
Drugprocaine

CACNA1D SCN3A SCN7A SCN9A

3.54e-05153284CID000004914
DrugAC1NSN3X

SCN3A SCN7A SCN9A

3.96e-0554283CID005366189
Drug2,3,5,6-tetrafluoro-4-methylbenzyl (Z)-(1RS)-cis-3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropanecarboxylate

SCN3A SCN8A

4.07e-058282ctd:C489827
Drugdihydrochloride

LGR5 SCN3A SCN7A SCN9A

4.11e-05159284CID000070978
Druglidocaine

SCN3A SCN5A SCN7A SCN9A

4.22e-05160284CID000003676
Drugamiodarone

SCN3A SCN5A SCN7A SCN9A

4.22e-05160284CID000002156
Drugtriamterene

SCN3A SCN7A SCN9A

4.91e-0558283CID000005546
DrugMexiletine

SCN5A SCN9A

5.22e-059282ctd:D008801
Drugzonisamide

SCN3A SCN7A SCN9A

6.00e-0562283CID000005734
Drugfenfluramine

ELOVL6 SCN3A SCN7A SCN9A

6.39e-05178284CID000003337
Drugcarbamazepine

SCN3A SCN5A SCN7A SCN9A

6.53e-05179284CID000002554
Drugmibefradil

CACNA1D SCN5A SCN9A

6.60e-0564283CID000060662
Drugsaxitoxin

SCN3A SCN7A SCN9A

6.91e-0565283CID000037165
Drugresiniferatoxin

SCN3A SCN7A SCN9A

7.24e-0566283CID000104826
Drugprocainamide

SCN3A SCN5A SCN7A SCN9A

8.22e-05190284CID000004913
DrugGBR 12909

SCN3A SCN7A SCN9A

8.27e-0569283CID000003455
Drugpropofol

HCN2 SCN3A SCN7A SCN9A

8.39e-05191284CID000004943
DrugCalciferol [50-14-6]; Down 200; 10uM; PC3; HT_HG-U133A

PTPN21 SLC30A1 TMEM259 MFAP3L

8.39e-051912846746_DN
DrugSalbutamol [18559-94-9]; Down 200; 16.8uM; PC3; HT_HG-U133A

PTPN21 TMEM259 MFAP3L SCN9A

8.74e-051932843677_DN
DrugT2755

SCN3A SCN7A SCN9A

9.00e-0571283CID000005514
DrugFluvastatin sodium salt [93957-55-2]; Up 200; 9.2uM; PC3; HT_HG-U133A

PPP1R37 CACNA1D SCN1A MFAP3L

9.09e-051952846691_UP
DrugCGX 0596987; Up 200; 20uM; PC3; HT_HG-U133A

PTPN21 SLC30A1 TMEM259 SCN8A

9.09e-051952846417_UP
DrugAceclofenac [89796-99-6]; Up 200; 11.2uM; PC3; HT_HG-U133A

MAP3K13 PTPN21 EP400 SCN8A

9.46e-051972842117_UP
DrugDyclonine hydrochloride [536-43-6]; Up 200; 12.2uM; PC3; HT_HG-U133A

PTPN21 SLC30A1 TMEM259 MFAP3L

9.65e-051982847261_UP
DrugMethotrimeprazine maleat salt [7104-38-3]; Down 200; 9uM; PC3; HT_HG-U133A

PTPN21 ELOVL6 TMEM259 SCN8A

9.65e-051982847399_DN
DrugRibavirin [36791-04-5]; Down 200; 16.4uM; MCF7; HT_HG-U133A

CACNA1D PTPN21 TMEM259 MFAP3L

1.00e-042002846521_DN
Drugimide

SCN3A SCN7A SCN9A

1.02e-0474283CID000443040
Drug1, 3-diallylurea

SCN3A SCN7A SCN9A

1.02e-0474283CID000074537
Drugdiphenhydramine

SCN3A SCN7A SCN9A

1.06e-0475283CID000003100
Drugbupropion

SCN3A SCN7A SCN9A

1.33e-0481283CID000000444
Drugisoproterenol

CACNA1D HCN2 SCN3A SCN5A SCN7A SCN9A

1.36e-04669286CID000003779
DrugVerapamil

CACNA1D SCN5A

1.73e-0416282DB00661
Drugmoricizine

SCN5A SCN9A

2.20e-0418282CID000034632
DrugScorpion Venoms

SCN3A SCN9A

2.20e-0418282ctd:D012604
Drugtrimethoprim

SCN3A SCN7A SCN9A

2.41e-0499283CID000005578
DrugAC1NPPZW

CACNA1D SCN5A SCN9A

2.71e-04103283CID005183170
Drugphorone

DDX20 PTPN21 SLC30A1

2.95e-04106283ctd:C018637
Drugverapamil

CACNA1D SCN3A SCN5A SCN7A SCN9A

2.95e-04490285CID000002520
Drughydrochlorothiazide

SCN3A SCN7A SCN9A

4.25e-04120283CID000003639
Drugbupivacaine

SCN3A SCN7A SCN9A

4.79e-04125283CID000002474
DrugDPI 201-106

SCN5A SCN9A

5.40e-0428282CID000005190
Drugencainide

SCN5A SCN9A

5.40e-0428282CID000048040
Drugoxcarbazepine

SCN5A SCN9A

6.21e-0430282CID000034312
Drugclenbuterol

SCN3A SCN7A SCN9A

6.94e-04142283CID000002783
Drugdecamethrin

SCN1A SCN3A SCN8A

7.52e-04146283ctd:C017180
Drugsalbutamol

SCN3A SCN7A SCN9A

7.52e-04146283CID000002083
DrugNSC15627

SCN5A SCN9A

7.99e-0434282CID000002073
Drugsodium

CACNA1D HCN2 SCN3A SCN5A SCN7A SCN9A

8.60e-04944286CID000000923
DrugLanatoside C [17575-22-3]; Up 200; 4uM; PC3; HT_HG-U133A

MAP3K13 PTPN21 SLC30A1

1.02e-031622833771_UP
Drugranolazine

SCN5A SCN9A

1.05e-0339282CID000056959
Drugrosiglitazone; Up 200; 10uM; PC3; HT_HG-U133A

ELOVL6 SLC30A1 SCN9A

1.13e-031682831233_UP
DrugMefloquine hydrochloride [51773-92-3]; Up 200; 9.6uM; PC3; HT_HG-U133A

CACNA1D MAP3K13 SLC30A1

1.15e-031692835724_UP
Drugpotassium

CACNA1D HCN2 SCN3A SCN5A SCN7A SCN9A

1.21e-031008286CID000000813
Diseasegeneralized epilepsy with febrile seizures plus 2 (implicated_via_orthology)

SCN1A SCN3A SCN5A SCN7A SCN8A SCN9A

8.61e-1710286DOID:0111294 (implicated_via_orthology)
DiseaseDravet syndrome (implicated_via_orthology)

SCN1A SCN3A SCN5A SCN7A SCN8A SCN9A

8.61e-1710286DOID:0080422 (implicated_via_orthology)
Diseasegeneralized epilepsy with febrile seizures plus (implicated_via_orthology)

SCN1A SCN3A SCN5A SCN7A SCN8A SCN9A

3.78e-1612286DOID:0060170 (implicated_via_orthology)
Diseaseepilepsy (implicated_via_orthology)

SCN1A SCN3A SCN5A SCN7A SCN8A SCN9A

8.83e-09163286DOID:1826 (implicated_via_orthology)
DiseaseEarly Infantile Epileptic Encephalopathy 6

SCN1A SCN9A

8.68e-072282C4551549
Diseaseanxiety disorder (implicated_via_orthology)

SCN1A SCN3A SCN9A

1.16e-0622283DOID:2030 (implicated_via_orthology)
DiseaseB Virus Infection

SCN8A SCN9A

2.60e-063282C0037140
DiseasePostherpetic neuralgia

SCN8A SCN9A

2.60e-063282C0032768
DiseaseHerpesviridae Infections

SCN8A SCN9A

2.60e-063282C0019372
DiseaseSick Sinus Syndrome

CACNA1D SCN5A

1.30e-056282C0037052
DiseaseEarly Childhood Epilepsy, Myoclonic

SCN1A SCN9A

2.42e-058282C0393695
DiseaseIdiopathic Myoclonic Epilepsy

SCN1A SCN9A

2.42e-058282C0338478
DiseaseSymptomatic Myoclonic Epilepsy

SCN1A SCN9A

2.42e-058282C0338479
DiseaseMyoclonic Encephalopathy

SCN1A SCN9A

2.42e-058282C0438414
DiseaseBenign Infantile Myoclonic Epilepsy

SCN1A SCN9A

2.42e-058282C0751120
DiseaseMyoclonic Absence Epilepsy

SCN1A SCN9A

2.42e-058282C0393703
DiseaseMyoclonic Epilepsy

SCN1A SCN9A

3.11e-059282C0014550
DiseaseGeneralized Epilepsy with Febrile Seizures Plus

SCN1A SCN9A

3.11e-059282C3502809
DiseaseEpilepsy, Myoclonic, Infantile

SCN1A SCN9A

3.89e-0510282C0917800
DiseaseMyoclonic Astatic Epilepsy

SCN1A SCN9A

4.75e-0511282C0393702
DiseaseInfantile Severe Myoclonic Epilepsy

SCN1A SCN9A

6.73e-0513282C0751122
DiseaseEpilepsy

SCN1A SCN8A SCN9A

1.50e-04109283C0014544
Diseaseamyotrophic lateral sclerosis (implicated_via_orthology)

ATP13A5 EPG5

3.72e-0430282DOID:332 (implicated_via_orthology)
DiseaseNeuroblastoma

CHD6 TOP2A

9.14e-0447282C0027819

Protein segments in the cluster

PeptideGeneStartEntry
SQMILMLDILEMFLN

EP400

1921

Q96L91
MIVCLLFMMILLAKE

EPG5

2116

Q9HCE0
LMQDVAITLMVCLTM

ATP13A5

936

Q4VNC0
KLQLLMRMMARICLN

DEPDC1B

326

Q8WUY9
NQFMMLMQALVLFTL

DPY19L3

261

Q6ZPD9
MMMRIAQKCNINLLP

DDX20

421

Q9UHI6
IFLLMYLMILMCNGI

OR10AG1

21

Q8NH19
FTIVMVLNITRLCMM

MFAP3L

161

O75121
DMLRQQRMMLVQTLC

PTPN21

1141

Q16825
LMLLATALKMNMNLR

PPP1R37

236

O75864
NLYMELSAIMLQLEM

MAP3K13

481

O43283
MFITLSQITQMLMGC

ELOVL6

196

Q9H5J4
MPNLINTMMELRKCC

CHD6

731

Q8TD26
VFIVDLLQMLEMNMA

TMEM259

331

Q4ZIN3
ASAVMRICNLISMML

HCN2

361

Q9UL51
MFVLIMLNTLCLAMQ

CACNA1D

1211

Q01668
MVALILLNSLCFLMM

LGR5

726

O75473
ASMILLMAILFNNML

MT-ND2

66

P03891
DVTIMFLICLNMVTM

SCN5A

1531

Q14524
LIMCTILTNCIFMTM

SCN9A

131

Q15858
MLMLAQSNPQLFALM

SELENOO

506

Q9BVL4
SMLIMCTILTNCVFM

SCN3A

131

Q9NY46
GQTMCLIVFMLVMVI

SCN3A

956

Q9NY46
SMLIMCTILTNCVFM

SCN1A

131

P35498
QLAMDIIIMIRVCKM

CNBD2

21

Q96M20
CMILIVIFVAMLGML

TM9SF4

356

Q92544
MIIMCTILTNCVFMT

SCN8A

136

Q9UQD0
EMSLMMTIINLAQNF

TOP2A

761

P11388
IVMVLICFQAIAMMI

SCN7A

1256

Q01118
LLCMLALTFMFMVLE

SLC30A1

11

Q9Y6M5