Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	heparan sulfate 6-O-sulfotransferase activity	HS6ST2 HS6ST1	1.06e-05	3	38	2	GO:0017095
GeneOntologyMolecularFunction	cargo receptor activity	MRC1 DMBT1 ASGR2 CD163	2.02e-05	85	38	4	GO:0038024
GeneOntologyMolecularFunction	heparan sulfate proteoglycan binding	CFH SEMA5A CFHR4	2.25e-05	29	38	3	GO:0043395
GeneOntologyMolecularFunction	proteoglycan binding	CFH SEMA5A CFHR4	1.24e-04	51	38	3	GO:0043394
GeneOntologyMolecularFunction	glycosaminoglycan binding	CFH SEMA5A BCAN DMBT1 CFHR4	1.47e-04	268	38	5	GO:0005539
GeneOntologyMolecularFunction	complement component C3b binding	CFH CFHR4	2.30e-04	12	38	2	GO:0001851
GeneOntologyMolecularFunction	carbohydrate binding	MRC1 BCAN MRC2 ASGR2 GAA	2.88e-04	310	38	5	GO:0030246
GeneOntologyMolecularFunction	heparan sulfate sulfotransferase activity	HS6ST2 HS6ST1	3.65e-04	15	38	2	GO:0034483
GeneOntologyMolecularFunction	opsonin binding	CFH CFHR4	1.03e-03	25	38	2	GO:0001846
GeneOntologyMolecularFunction	scavenger receptor activity	DMBT1 CD163	1.20e-03	27	38	2	GO:0005044
GeneOntologyMolecularFunction	D-mannose binding	MRC1 ASGR2	1.20e-03	27	38	2	GO:0005537
GeneOntologyMolecularFunction	endopeptidase activity	ADAMTS17 ADAMTS14 PSMD14 PRSS12 PRSS36	1.26e-03	430	38	5	GO:0004175
GeneOntologyMolecularFunction	complement binding	CFH CFHR4	1.69e-03	32	38	2	GO:0001848
GeneOntologyMolecularFunction	sulfur compound binding	CFH SEMA5A DMBT1 CFHR4	3.22e-03	323	38	4	GO:1901681
GeneOntologyMolecularFunction	sulfotransferase activity	HS6ST2 HS6ST1	4.91e-03	55	38	2	GO:0008146
GeneOntologyMolecularFunction	antigen binding	IGHV3-35 IGHV5-51 IGHV4-28	5.60e-03	190	38	3	GO:0003823
GeneOntologyMolecularFunction	metallopeptidase activity	ADAMTS17 ADAMTS14 PSMD14	6.45e-03	200	38	3	GO:0008237
GeneOntologyMolecularFunction	peptidase activity	ADAMTS17 ADAMTS14 PSMD14 PRSS12 PRSS36	7.62e-03	654	38	5	GO:0008233
GeneOntologyMolecularFunction	transferase activity, transferring sulphur-containing groups	HS6ST2 HS6ST1	8.74e-03	74	38	2	GO:0016782
GeneOntologyMolecularFunction	virus receptor activity	MRC1 HYAL3	1.14e-02	85	38	2	GO:0001618
GeneOntologyMolecularFunction	exogenous protein binding	MRC1 HYAL3	1.17e-02	86	38	2	GO:0140272
GeneOntologyMolecularFunction	monosaccharide binding	MRC1 ASGR2	1.41e-02	95	38	2	GO:0048029
GeneOntologyMolecularFunction	hydrolase activity, hydrolyzing O-glycosyl compounds	HYAL3 GAA	1.64e-02	103	38	2	GO:0004553
GeneOntologyBiologicalProcess	activation of membrane attack complex	CFH CFHR4	4.93e-05	6	38	2	GO:0001905
GeneOntologyBiologicalProcess	immunoglobulin mediated immune response	CFH IGHV3-35 IGHV5-51 IGHV4-28 CFHR4	6.80e-05	235	38	5	GO:0016064
GeneOntologyBiologicalProcess	regulation of complement activation, alternative pathway	CFH CFHR4	6.90e-05	7	38	2	GO:0030451
GeneOntologyBiologicalProcess	B cell mediated immunity	CFH IGHV3-35 IGHV5-51 IGHV4-28 CFHR4	8.11e-05	244	38	5	GO:0019724
GeneOntologyBiologicalProcess	monocyte aggregation	CFH CFHR4	1.18e-04	9	38	2	GO:0070487
GeneOntologyBiologicalProcess	immune complex clearance	CFH CFHR4	1.18e-04	9	38	2	GO:0002434
GeneOntologyBiologicalProcess	regulation of ovarian follicle development	GNRH1 HYAL3	1.47e-04	10	38	2	GO:2000354
GeneOntologyBiologicalProcess	retinal pigment epithelium development	CFH CFHR4	1.47e-04	10	38	2	GO:0003406
GeneOntologyBiologicalProcess	heparan sulfate proteoglycan biosynthetic process, enzymatic modification	HS6ST2 HS6ST1	2.16e-04	12	38	2	GO:0015015
GeneOntologyBiologicalProcess	regulation of complement-dependent cytotoxicity	CFH CFHR4	2.55e-04	13	38	2	GO:1903659
GeneOntologyBiologicalProcess	complement-dependent cytotoxicity	CFH CFHR4	3.90e-04	16	38	2	GO:0097278
GeneOntologyBiologicalProcess	heparan sulfate proteoglycan metabolic process	HS6ST2 HS6ST1	4.42e-04	17	38	2	GO:0030201
GeneOntologyBiologicalProcess	retinal rod cell development	CFH CFHR4	4.42e-04	17	38	2	GO:0046548
GeneOntologyBiologicalProcess	complement activation, alternative pathway	CFH CFHR4	5.54e-04	19	38	2	GO:0006957
GeneOntologyBiologicalProcess	leukocyte aggregation	CFH CFHR4	5.54e-04	19	38	2	GO:0070486
GeneOntologyBiologicalProcess	retinal rod cell differentiation	CFH CFHR4	1.13e-03	27	38	2	GO:0060221
GeneOntologyBiologicalProcess	regulation of complement activation	CFH CFHR4	1.13e-03	27	38	2	GO:0030449
GeneOntologyBiologicalProcess	mitochondrial DNA metabolic process	CFH CFHR4	1.30e-03	29	38	2	GO:0032042
GeneOntologyBiologicalProcess	lymphocyte mediated immunity	CFH IGHV3-35 IGHV5-51 IGHV4-28 CFHR4	1.33e-03	449	38	5	GO:0002449
GeneOntologyCellularComponent	symbiont cell surface	CFH CFHR4	9.43e-05	8	39	2	GO:0106139
GeneOntologyCellularComponent	other organism part	CFH CFHR4	1.21e-04	9	39	2	GO:0044217
GeneOntologyCellularComponent	cell surface	CFH MRC1 DUOX1 BCAN EGFL7 MRC2 ASGR2 CD163 CFHR4	1.63e-04	1111	39	9	GO:0009986
GeneOntologyCellularComponent	serine-type endopeptidase complex	CFH CFHR4	6.31e-04	20	39	2	GO:1905370
GeneOntologyCellularComponent	serine-type peptidase complex	CFH CFHR4	7.65e-04	22	39	2	GO:1905286
GeneOntologyCellularComponent	endopeptidase complex	CFH PSMD14 CFHR4	9.07e-04	102	39	3	GO:1905369
GeneOntologyCellularComponent	peptidase complex	CFH PSMD14 CFHR4	1.95e-03	133	39	3	GO:1905368
GeneOntologyCellularComponent	immunoglobulin complex	IGHV3-35 IGHV5-51 IGHV4-28	3.64e-03	166	39	3	GO:0019814
MousePheno	artery occlusion	CFH CFHR4	2.59e-06	2	23	2	MP:0006134
MousePheno	white pupil	CFH CFHR4	2.59e-06	2	23	2	MP:0006242
MousePheno	decreased complement C5 level	CFH CFHR4	2.59e-06	2	23	2	MP:0012609
MousePheno	abnormal complement C5 level	CFH CFHR4	2.59e-06	2	23	2	MP:0012608
MousePheno	decreased serum complement activity	CFH CFHR4	2.59e-06	2	23	2	MP:0012553
MousePheno	abnormal hepatic portal vein thrombosis	CFH CFHR4	2.59e-06	2	23	2	MP:0031159
MousePheno	increased susceptilbility to retina ischemic injury	CFH CFHR4	7.76e-06	3	23	2	MP:0012049
MousePheno	abnormal kidney venous thrombosis	CFH CFHR4	7.76e-06	3	23	2	MP:0031161
MousePheno	abnormal response to retina ischemic injury	CFH CFHR4	1.55e-05	4	23	2	MP:0012048
MousePheno	decreased circulating complement protein level	CFH CFHR4	1.55e-05	4	23	2	MP:0020216
MousePheno	mesangial cell interposition	CFH CFHR4	1.55e-05	4	23	2	MP:0011512
MousePheno	abnormal brain thrombosis	CFH CFHR4	1.55e-05	4	23	2	MP:0031168
MousePheno	increased susceptibility to type III hypersensitivity reaction	CFH CFHR4	1.55e-05	4	23	2	MP:0005615
MousePheno	increased creatine level	CFH CFHR4	1.55e-05	4	23	2	MP:0010061
MousePheno	abnormal venous thrombosis	CFH CFHR4	2.58e-05	5	23	2	MP:0031158
MousePheno	abnormal lung thrombosis	CFH CFHR4	2.58e-05	5	23	2	MP:0031167
MousePheno	abnormal circulating complement protein level	CFH CFHR4	3.87e-05	6	23	2	MP:0010215
MousePheno	abnormal glomerular capillary thrombosis	CFH CFHR4	5.41e-05	7	23	2	MP:0011508
MousePheno	brain ischemia	CFH CFHR4	7.21e-05	8	23	2	MP:0006080
MousePheno	abnormal complement protein level	CFH CFHR4	9.26e-05	9	23	2	MP:0011566
MousePheno	abnormal creatine level	CFH CFHR4	9.26e-05	9	23	2	MP:0010060
MousePheno	abnormal kidney thrombosis	CFH CFHR4	1.16e-04	10	23	2	MP:0011507
MousePheno	abnormal type III hypersensitivity reaction	CFH CFHR4	1.16e-04	10	23	2	MP:0002533
MousePheno	decreased visual acuity	CFH CFHR4	2.00e-04	13	23	2	MP:0006149
MousePheno	abnormal visual acuity	CFH CFHR4	2.00e-04	13	23	2	MP:0011832
MousePheno	abnormal Bruch membrane morphology	CFH CFHR4	2.33e-04	14	23	2	MP:0005239
MousePheno	retina detachment	CFH CFHR4	2.68e-04	15	23	2	MP:0003099
MousePheno	hindlimb paralysis	CFH GAA CFHR4	2.84e-04	79	23	3	MP:0000755
MousePheno	limb paralysis	CFH GAA CFHR4	3.28e-04	83	23	3	MP:0013147
MousePheno	amyloid beta deposits	CFH CFHR4	3.47e-04	17	23	2	MP:0003329
MousePheno	hematuria	CFH CFHR4	4.35e-04	19	23	2	MP:0005161
MousePheno	abnormal glomerular capillary endothelium morphology	CFH CFHR4	5.34e-04	21	23	2	MP:0011453
MousePheno	abnormal retina rod bipolar cell morphology	CFH CFHR4	6.42e-04	23	23	2	MP:0006074
MousePheno	abnormal complement pathway	CFH CFHR4	8.22e-04	26	23	2	MP:0002471
MousePheno	abnormal gastrocnemius morphology	ZNF106 CD163	8.86e-04	27	23	2	MP:0003082
MousePheno	paralysis	CFH GAA CFHR4	9.41e-04	119	23	3	MP:0000753
MousePheno	impaired muscle relaxation	CFH CFHR4	9.54e-04	28	23	2	MP:0003157
MousePheno	increased mesangial cell number	CFH CFHR4	1.02e-03	29	23	2	MP:0011427
MousePheno	renal glomerular immunoglobulin deposits	CFH CFHR4	1.41e-03	34	23	2	MP:0020519
MousePheno	amyloidosis	CFH CFHR4	1.49e-03	35	23	2	MP:0000604
MousePheno	increased circulating luteinizing hormone level	MRC1 GNRH1	1.49e-03	35	23	2	MP:0001751
MousePheno	abnormal amyloid deposition	CFH CFHR4	1.49e-03	35	23	2	MP:0021152
MousePheno	disorganized photoreceptor outer segment	CFH CFHR4	1.58e-03	36	23	2	MP:0008586
MousePheno	abnormal retina bipolar cell morphology	CFH CFHR4	1.67e-03	37	23	2	MP:0006073
MousePheno	abnormal mesangial cell morphology	CFH CFHR4	1.76e-03	38	23	2	MP:0005327
MousePheno	increased luteinizing hormone level	MRC1 GNRH1	1.76e-03	38	23	2	MP:0005133
MousePheno	renal glomerular protein deposits	CFH CFHR4	2.14e-03	42	23	2	MP:0020518
MousePheno	nervous system inclusion bodies	CFH CFHR4	2.14e-03	42	23	2	MP:0014062
MousePheno	intracerebral hemorrhage	CFH CFHR4	2.35e-03	44	23	2	MP:0001916
MousePheno	abnormal renal glomerulus basement membrane morphology	CFH CFHR4	2.35e-03	44	23	2	MP:0011348
MousePheno	expanded mesangial matrix	CFH CFHR4	2.56e-03	46	23	2	MP:0011353
MousePheno	abnormal glomerular capillary morphology	CFH CFHR4	2.68e-03	47	23	2	MP:0011320
MousePheno	abnormal kidney capillary morphology	CFH CFHR4	2.79e-03	48	23	2	MP:0011310
MousePheno	abnormal mesangial matrix morphology	CFH CFHR4	3.14e-03	51	23	2	MP:0011338
MousePheno	abnormal optic choroid morphology	CFH CFHR4	3.27e-03	52	23	2	MP:0005098
MousePheno	abnormal external male genitalia morphology	ZNF106 GNRH1	3.39e-03	53	23	2	MP:0009199
MousePheno	abnormal retina vasculature morphology	CFH EGFL7 CD163 CFHR4	3.47e-03	390	23	4	MP:0002792
MousePheno	abnormal circulating estrogen level	MRC1 GNRH1	3.91e-03	57	23	2	MP:0003369
Domain	NPIP	NPIPA1 NPIPA3 NPIPA7 NPIPB2 NPIPA5	3.94e-11	14	36	5	IPR009443
Domain	C-type_lectin_CS	MRC1 BCAN MRC2 ASGR2	1.36e-06	43	36	4	IPR018378
Domain	TSP_1	ADAMTS17 SEMA5A THSD7B ADAMTS14	6.38e-06	63	36	4	PF00090
Domain	TSP1	ADAMTS17 SEMA5A THSD7B ADAMTS14	7.24e-06	65	36	4	SM00209
Domain	TSP1_rpt	ADAMTS17 SEMA5A THSD7B ADAMTS14	7.24e-06	65	36	4	IPR000884
Domain	TSP1	ADAMTS17 SEMA5A THSD7B ADAMTS14	7.24e-06	65	36	4	PS50092
Domain	SRCR	DMBT1 PRSS12 CD163	8.54e-06	21	36	3	PF00530
Domain	Heparan_SO4-6-sulfoTrfase	HS6ST2 HS6ST1	1.08e-05	3	36	2	IPR010635
Domain	SR	DMBT1 PRSS12 CD163	1.47e-05	25	36	3	SM00202
Domain	-	DMBT1 PRSS12 CD163	1.47e-05	25	36	3	3.10.250.10
Domain	C_TYPE_LECTIN_1	MRC1 BCAN MRC2 ASGR2	1.66e-05	80	36	4	PS00615
Domain	SRCR_1	DMBT1 PRSS12 CD163	1.66e-05	26	36	3	PS00420
Domain	SRCR-like_dom	DMBT1 PRSS12 CD163	1.66e-05	26	36	3	IPR017448
Domain	SRCR_2	DMBT1 PRSS12 CD163	1.66e-05	26	36	3	PS50287
Domain	SRCR	DMBT1 PRSS12 CD163	1.86e-05	27	36	3	IPR001190
Domain	Lectin_C	MRC1 BCAN MRC2 ASGR2	2.01e-05	84	36	4	PF00059
Domain	CLECT	MRC1 BCAN MRC2 ASGR2	2.01e-05	84	36	4	SM00034
Domain	C_TYPE_LECTIN_2	MRC1 BCAN MRC2 ASGR2	2.11e-05	85	36	4	PS50041
Domain	C-type_lectin-like	MRC1 BCAN MRC2 ASGR2	2.21e-05	86	36	4	IPR001304
Domain	Kringle-like	MRC1 PRSS12 MRC2	3.14e-05	32	36	3	IPR013806
Domain	-	MRC1 BCAN MRC2 ASGR2	3.54e-05	97	36	4	3.10.100.10
Domain	C-type_lectin-like/link	MRC1 BCAN MRC2 ASGR2	3.84e-05	99	36	4	IPR016186
Domain	CTDL_fold	MRC1 BCAN MRC2 ASGR2	5.21e-05	107	36	4	IPR016187
Domain	Sushi	CFH BCAN CFHR4	1.36e-04	52	36	3	PF00084
Domain	CCP	CFH BCAN CFHR4	1.52e-04	54	36	3	SM00032
Domain	SUSHI	CFH BCAN CFHR4	1.70e-04	56	36	3	PS50923
Domain	Sushi_SCR_CCP_dom	CFH BCAN CFHR4	1.79e-04	57	36	3	IPR000436
Domain	Sulfotransfer_2	HS6ST2 HS6ST1	2.36e-04	12	36	2	PF03567
Domain	Sulfotransferase	HS6ST2 HS6ST1	2.36e-04	12	36	2	IPR005331
Domain	-	MRC1 MRC2	2.78e-04	13	36	2	2.10.10.10
Domain	FN_type2_col-bd	MRC1 MRC2	3.24e-04	14	36	2	IPR000562
Domain	FN2_2	MRC1 MRC2	3.24e-04	14	36	2	PS51092
Domain	fn2	MRC1 MRC2	3.24e-04	14	36	2	PF00040
Domain	FN2_1	MRC1 MRC2	3.24e-04	14	36	2	PS00023
Domain	FN2	MRC1 MRC2	3.24e-04	14	36	2	SM00059
Domain	PLAC	ADAMTS17 ADAMTS14	6.05e-04	19	36	2	IPR010909
Domain	PLAC	ADAMTS17 ADAMTS14	6.05e-04	19	36	2	PS50900
Domain	ADAM_spacer1	ADAMTS17 ADAMTS14	8.91e-04	23	36	2	IPR010294
Domain	ADAM_spacer1	ADAMTS17 ADAMTS14	8.91e-04	23	36	2	PF05986
Domain	Peptidase_M12B_ADAM-TS	ADAMTS17 ADAMTS14	9.71e-04	24	36	2	IPR013273
Domain	Ricin_B_lectin	MRC1 MRC2	1.05e-03	25	36	2	PF00652
Domain	ADAM_Cys-rich	ADAMTS17 ADAMTS14	1.23e-03	27	36	2	IPR006586
Domain	ACR	ADAMTS17 ADAMTS14	1.23e-03	27	36	2	SM00608
Domain	RICIN	MRC1 MRC2	1.32e-03	28	36	2	SM00458
Domain	RICIN_B_LECTIN	MRC1 MRC2	1.32e-03	28	36	2	PS50231
Domain	Ricin_B_lectin	MRC1 MRC2	1.52e-03	30	36	2	IPR000772
Domain	Peptidase_M12B_N	ADAMTS17 ADAMTS14	2.56e-03	39	36	2	IPR002870
Domain	Pep_M12B_propep	ADAMTS17 ADAMTS14	2.56e-03	39	36	2	PF01562
Domain	DISINTEGRIN_1	ADAMTS17 ADAMTS14	2.69e-03	40	36	2	PS00427
Domain	ADAM_MEPRO	ADAMTS17 ADAMTS14	2.69e-03	40	36	2	PS50215
Domain	DISINTEGRIN_2	ADAMTS17 ADAMTS14	2.69e-03	40	36	2	PS50214
Domain	Reprolysin	ADAMTS17 ADAMTS14	2.69e-03	40	36	2	PF01421
Domain	Peptidase_M12B	ADAMTS17 ADAMTS14	2.69e-03	40	36	2	IPR001590
Domain	CYSTEINE_SWITCH	ADAMTS17 ADAMTS14	2.83e-03	41	36	2	PS00546
Domain	Disintegrin_dom	ADAMTS17 ADAMTS14	2.83e-03	41	36	2	IPR001762
Domain	Pept_M10_metallopeptidase	ADAMTS17 ADAMTS14	3.10e-03	43	36	2	IPR001818
Domain	Glycoside_hydrolase_SF	HYAL3 GAA	4.68e-03	53	36	2	IPR017853
Domain	EGF_3	BCAN EGFL7 HYAL3	1.03e-02	235	36	3	PS50026
Domain	EGF	BCAN EGFL7 HYAL3	1.03e-02	235	36	3	SM00181
Domain	MetalloPept_cat_dom	ADAMTS17 ADAMTS14	1.06e-02	81	36	2	IPR024079
Domain	-	ADAMTS17 ADAMTS14	1.06e-02	81	36	2	3.40.390.10
Domain	EGF-like_dom	BCAN EGFL7 HYAL3	1.21e-02	249	36	3	IPR000742
Domain	EGF_1	BCAN EGFL7 HYAL3	1.29e-02	255	36	3	PS00022
Domain	TRYPSIN_SER	PRSS12 PRSS36	1.30e-02	90	36	2	IPR033116
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	ADAMTS17 SEMA5A THSD7B ADAMTS14	4.26e-07	39	23	4	M27417
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	ADAMTS17 SEMA5A THSD7B ADAMTS14	4.26e-07	39	23	4	MM15165
Pathway	REACTOME_DISEASES_OF_METABOLISM	ADAMTS17 SEMA5A BCAN THSD7B ADAMTS14 GAA	2.30e-06	250	23	6	M27554
Pathway	REACTOME_DISEASES_OF_GLYCOSYLATION	ADAMTS17 SEMA5A BCAN THSD7B ADAMTS14	2.91e-06	143	23	5	M27275
Pathway	REACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS	ADAMTS17 SEMA5A THSD7B ADAMTS14	4.09e-06	68	23	4	M27303
Pathway	WP_FATTY_ACIDS_AND_LIPOPROTEINS_TRANSPORT_IN_HEPATOCYTES	MRC1 DMBT1 PRSS12 MRC2 ASGR2 CD163	2.56e-05	381	23	6	M48063
Pathway	REACTOME_O_LINKED_GLYCOSYLATION	ADAMTS17 SEMA5A THSD7B ADAMTS14	2.67e-05	109	23	4	MM15164
Pathway	REACTOME_O_LINKED_GLYCOSYLATION	ADAMTS17 SEMA5A THSD7B ADAMTS14	2.87e-05	111	23	4	M27416
Pathway	KEGG_MEDICUS_REFERENCE_REGULATION_OF_COMPLEMENT_CASCADE_CFHR	CFH CFHR4	3.80e-05	6	23	2	M47880
Pathway	REACTOME_GLYCOSAMINOGLYCAN_METABOLISM	BCAN HS6ST2 HS6ST1 HYAL3	4.30e-05	123	23	4	MM14623
Pathway	REACTOME_GLYCOSAMINOGLYCAN_METABOLISM	BCAN HS6ST2 HS6ST1 HYAL3	4.72e-05	126	23	4	M695
Pathway	REACTOME_CROSS_PRESENTATION_OF_SOLUBLE_EXOGENOUS_ANTIGENS_ENDOSOMES	MRC1 PSMD14 MRC2	6.25e-05	48	23	3	MM14528
Pathway	REACTOME_METABOLISM_OF_CARBOHYDRATES	BCAN HS6ST2 HS6ST1 HYAL3 GAA	6.41e-05	271	23	5	MM15406
Pathway	REACTOME_CROSS_PRESENTATION_OF_SOLUBLE_EXOGENOUS_ANTIGENS_ENDOSOMES	MRC1 PSMD14 MRC2	7.07e-05	50	23	3	M510
Pathway	REACTOME_METABOLISM_OF_CARBOHYDRATES	BCAN HS6ST2 HS6ST1 HYAL3 GAA	8.55e-05	288	23	5	M16864
Pathway	REACTOME_HEPARAN_SULFATE_HEPARIN_HS_GAG_METABOLISM	BCAN HS6ST2 HS6ST1	8.91e-05	54	23	3	MM14633
Pathway	REACTOME_HEPARAN_SULFATE_HEPARIN_HS_GAG_METABOLISM	BCAN HS6ST2 HS6ST1	1.05e-04	57	23	3	M692
Pathway	REACTOME_CS_DS_DEGRADATION	BCAN HYAL3	1.96e-04	13	23	2	MM14805
Pathway	REACTOME_CS_DS_DEGRADATION	BCAN HYAL3	2.29e-04	14	23	2	M651
Pathway	REACTOME_ANTIGEN_PROCESSING_CROSS_PRESENTATION	MRC1 PSMD14 MRC2	2.47e-04	76	23	3	MM14526
Pathway	REACTOME_COMPLEMENT_CASCADE	CFH IGHV4-28 CFHR4	3.32e-04	84	23	3	MM14653
Pathway	REACTOME_ANTIGEN_PROCESSING_CROSS_PRESENTATION	MRC1 PSMD14 MRC2	6.56e-04	106	23	3	M518
Pathway	KEGG_GLYCOSAMINOGLYCAN_BIOSYNTHESIS_HEPARAN_SULFATE	HS6ST2 HS6ST1	8.08e-04	26	23	2	M7330
Pathway	REACTOME_HS_GAG_BIOSYNTHESIS	HS6ST2 HS6ST1	1.01e-03	29	23	2	MM14802
Pathway	REACTOME_HS_GAG_BIOSYNTHESIS	HS6ST2 HS6ST1	1.15e-03	31	23	2	M685
Pathway	WP_GLYCOSAMINOGLYCAN_SYNTHESIS_IN_FIBROBLASTS	HS6ST2 HS6ST1	2.01e-03	41	23	2	M48095
Pathway	REACTOME_CHONDROITIN_SULFATE_DERMATAN_SULFATE_METABOLISM	BCAN HYAL3	2.74e-03	48	23	2	MM14696
Pathway	REACTOME_CHONDROITIN_SULFATE_DERMATAN_SULFATE_METABOLISM	BCAN HYAL3	2.97e-03	50	23	2	M678
Pubmed	Nucleotide sequence of the partially deleted D4Z4 locus in a patient with FSHD identifies a putative gene within each 3.3 kb element.	DUX4L2 DUX4 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7 DUX4L9	2.92e-21	12	47	8	10433963
Pubmed	Evolutionary conservation of a coding function for D4Z4, the tandem DNA repeat mutated in facioscapulohumeral muscular dystrophy.	DUX4L2 DUX4 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7 DUX4L9	7.59e-21	13	47	8	17668377
Pubmed	The DUX4 gene at the FSHD1A locus encodes a pro-apoptotic protein.	DUX4L2 DUX4 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7	4.12e-20	8	47	7	17588759
Pubmed	DUX4, a candidate gene of facioscapulohumeral muscular dystrophy, encodes a transcriptional activator of PITX1.	DUX4L2 DUX4 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7	6.17e-19	10	47	7	17984056
Pubmed	Characterization of a tandemly repeated 3.3-kb KpnI unit in the facioscapulohumeral muscular dystrophy (FSHD) gene region on chromosome 4q35.	DUX4L2 DUX4 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7	8.79e-18	13	47	7	7739628
Pubmed	Active genes in junk DNA? Characterization of DUX genes embedded within 3.3 kb repeated elements.	DUX4L2 DUX4 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7	9.92e-17	17	47	7	11245978
Pubmed	Expression profiling of immature thymocytes revealed a novel homeobox gene that regulates double-negative thymocyte development.	DUX4L2 DUX4L4 DUX4L9	9.24e-09	4	47	3	17911620
Pubmed	Novel retinal and cone photoreceptor transcripts revealed by human macular expression profiling.	NPIPA1 NPIPA3 NPIPA5	9.24e-09	4	47	3	18055785
Pubmed	The homeobox transcription factor DUXBL controls exit from totipotency.	DUX4L2 DUX4L4 DUX4L9	9.24e-09	4	47	3	38509386
Pubmed	Characterization of genomic structures and expression profiles of three tandem repeats of a mouse double homeobox gene: Duxbl.	DUX4L2 DUX4L4 DUX4L9	2.31e-08	5	47	3	20063414
Pubmed	The transcription factor Duxbl mediates elimination of pre-T cells that fail β-selection.	DUX4L2 DUX4L4 DUX4L9	8.06e-08	7	47	3	30765463
Pubmed	Proteomic analysis identifies transcriptional cofactors and homeobox transcription factors as TBX18 binding proteins.	DUX4L2 DUX4L4 DUX4L9	1.04e-06	15	47	3	30071041
Pubmed	Mutations in MINAR2 encoding membrane integral NOTCH2-associated receptor 2 cause deafness in humans and mice.	DUX4L2 DUX4L4 DUX4L9	1.04e-06	15	47	3	35727972
Pubmed	Complement Factor H Modulates Splenic B Cell Development and Limits Autoantibody Production.	CFH CFHR4	1.79e-06	2	47	2	31354740
Pubmed	Local complement factor H protects kidney endothelial cell structure and function.	CFH CFHR4	1.79e-06	2	47	2	34139209
Pubmed	Systemic administration of Abeta mAb reduces retinal deposition of Abeta and activated complement C3 in age-related macular degeneration mouse model.	CFH CFHR4	1.79e-06	2	47	2	23799019
Pubmed	Circulating FH Protects Kidneys From Tubular Injury During Systemic Hemolysis.	CFH CFHR4	1.79e-06	2	47	2	32849636
Pubmed	Complement factor h is critical in the maintenance of retinal perfusion.	CFH CFHR4	1.79e-06	2	47	2	19541934
Pubmed	Complement factor H deficiency in aged mice causes retinal abnormalities and visual dysfunction.	CFH CFHR4	1.79e-06	2	47	2	17921253
Pubmed	The role of complement dysregulation in AMD mouse models.	CFH CFHR4	1.79e-06	2	47	2	24664701
Pubmed	Mitochondrial decline precedes phenotype development in the complement factor H mouse model of retinal degeneration but can be corrected by near infrared light.	CFH CFHR4	1.79e-06	2	47	2	26149919
Pubmed	Absence of complement factor H reduces physical performance in C57BL6 mice.	CFH CFHR4	1.79e-06	2	47	2	32962822
Pubmed	Murine protein H is comprised of 20 repeating units, 61 amino acids in length.	CFH CFHR4	1.79e-06	2	47	2	2940596
Pubmed	A receptor for the complement regulator factor H increases transmission of trypanosomes to tsetse flies.	CFH CFHR4	1.79e-06	2	47	2	32165615
Pubmed	Transgenic mice expressing variants of complement factor H develop AMD-like retinal findings.	CFH CFHR4	1.79e-06	2	47	2	20538999
Pubmed	Oligomerization of the macrophage mannose receptor enhances gp120-mediated binding of HIV-1.	MRC1 MRC2	1.79e-06	2	47	2	19224860
Pubmed	Inheritance, hormonal regulation and properties of polymorphic murine antigens Mud1 and Mud2.	CFH CFHR4	1.79e-06	2	47	2	4992636
Pubmed	Retinal changes precede visual dysfunction in the complement factor H knockout mouse.	CFH CFHR4	1.79e-06	2	47	2	23844226
Pubmed	Death by color: differential cone loss in the aging mouse retina.	CFH CFHR4	1.79e-06	2	47	2	24929970
Pubmed	Cfh genotype interacts with dietary glycemic index to modulate age-related macular degeneration-like features in mice.	CFH CFHR4	1.79e-06	2	47	2	24370827
Pubmed	CD163 and CD206 expression does not correlate with tolerance and cytokine production in LPS-tolerant human monocytes.	MRC1 CD163	1.79e-06	2	47	2	26352275
Pubmed	Prediction from sequence comparisons of residues of factor H involved in the interaction with complement component C3b.	CFH CFHR4	1.79e-06	2	47	2	8615824
Pubmed	Cadmium Induces Glomerular Endothelial Cell-Specific Expression of Complement Factor H via the -1635 AP-1 Binding Site.	CFH CFHR4	1.79e-06	2	47	2	30642982
Pubmed	Essential role of surface-bound complement factor H in controlling immune complex-induced arthritis.	CFH CFHR4	1.79e-06	2	47	2	23436934
Pubmed	Partial Complement Factor H Deficiency Associates with C3 Glomerulopathy and Thrombotic Microangiopathy.	CFH CFHR4	1.79e-06	2	47	2	26374608
Pubmed	Defective regulation of microRNA target genes in myoblasts from facioscapulohumeral dystrophy patients.	DUX4 DUX4L9	1.79e-06	2	47	2	24145033
Pubmed	Treatment with 670 nm light up regulates cytochrome C oxidase expression and reduces inflammation in an age-related macular degeneration model.	CFH CFHR4	1.79e-06	2	47	2	23469078
Pubmed	A gene locus concerned with an antigenic serum substance in Mus musculus.	CFH CFHR4	1.79e-06	2	47	2	4955525
Pubmed	Analysis of complement factor H mRNA expression: dexamethasone and IFN-gamma increase the level of H in L cells.	CFH CFHR4	1.79e-06	2	47	2	2533512
Pubmed	Complement factor H: spatial and temporal expression and localization in the eye.	CFH CFHR4	1.79e-06	2	47	2	16936129
Pubmed	Mannose receptor regulation of macrophage cell migration.	MRC1 MRC2	1.79e-06	2	47	2	17596337
Pubmed	Topical cyclodextrin reduces amyloid beta and inflammation improving retinal function in ageing mice.	CFH CFHR4	1.79e-06	2	47	2	25921262
Pubmed	Positive selection of a gene family during the emergence of humans and African apes.	NPIPA1 NPIPA8	1.79e-06	2	47	2	11586358
Pubmed	Complement factor h limits immune complex deposition and prevents inflammation and scarring in glomeruli of mice with chronic serum sickness.	CFH CFHR4	1.79e-06	2	47	2	15574507
Pubmed	Watching synchronous mitochondrial respiration in the retina and its instability in a mouse model of macular degeneration.	CFH CFHR4	1.79e-06	2	47	2	33558624
Pubmed	Genome-Wide Association Study Reveals Variants in CFH and CFHR4 Associated with Systemic Complement Activation: Implications in Age-Related Macular Degeneration.	CFH CFHR4	1.79e-06	2	47	2	29398083
Pubmed	Complement factor H Y402H polymorphism results in diminishing CD4+ T cells and increasing C-reactive protein in plasma.	CFH CFHR4	1.79e-06	2	47	2	37940659
Pubmed	Comparative analysis of the properties and ligand binding characteristics of CspZ, a factor H binding protein, derived from Borrelia burgdorferi isolates of human origin.	CFH CFHR4	1.79e-06	2	47	2	19620346
Pubmed	Complement factor H regulates retinal development and its absence may establish a footprint for age related macular degeneration.	CFH CFHR4	1.79e-06	2	47	2	30705315
Pubmed	Design and evaluation of meningococcal vaccines through structure-based modification of host and pathogen molecules.	CFH CFHR4	1.79e-06	2	47	2	23133374
Pubmed	HIV-1 Tat represses transcription from the mannose receptor promoter.	MRC1 MRC2	1.79e-06	2	47	2	11120831
Pubmed	Human complement factor H Y402H polymorphism causes an age-related macular degeneration phenotype and lipoprotein dysregulation in mice.	CFH CFHR4	1.79e-06	2	47	2	30808757
Pubmed	Binding of factor H to tubular epithelial cells limits interstitial complement activation in ischemic injury.	CFH CFHR4	1.79e-06	2	47	2	21544060
Pubmed	Noninfectious entry of HIV-1 into peripheral and brain macrophages mediated by the mannose receptor.	MRC1 MRC2	1.79e-06	2	47	2	17360361
Pubmed	A complement factor H homolog, heparan sulfation, and syndecan maintain inversin compartment boundaries in C. elegans cilia.	CFH CFHR4	1.79e-06	2	47	2	33859044
Pubmed	Regulation of age-related macular degeneration-like pathology by complement factor H.	CFH CFHR4	1.79e-06	2	47	2	25991857
Pubmed	Association of human mannose receptor in sexual transmission of human immunodeficiency virus in serodiscordant couples.	MRC1 MRC2	1.79e-06	2	47	2	23148569
Pubmed	Role of ocular complement factor H in a murine model of choroidal neovascularization.	CFH CFHR4	1.79e-06	2	47	2	20813971
Pubmed	Location of the mouse complement factor H gene (cfh) by FISH analysis and replication R-banding.	CFH CFHR4	1.79e-06	2	47	2	1486806
Pubmed	A chimeric Cfh transgene leads to increased retinal oxidative stress, inflammation, and accumulation of activated subretinal microglia in mice.	CFH CFHR4	1.79e-06	2	47	2	26030099
Pubmed	Spontaneous hemolytic uremic syndrome triggered by complement factor H lacking surface recognition domains.	CFH CFHR4	1.79e-06	2	47	2	17517971
Pubmed	Treatment with human complement factor H rapidly reverses renal complement deposition in factor H-deficient mice.	CFH CFHR4	1.79e-06	2	47	2	20445496
Pubmed	Possible role of complement factor H in podocytes in clearing glomerular subendothelial immune complex deposits.	CFH CFHR4	1.79e-06	2	47	2	31133737
Pubmed	High-density lipoproteins are a potential therapeutic target for age-related macular degeneration.	CFH CFHR4	1.79e-06	2	47	2	32737203
Pubmed	The mannose receptor on murine liver sinusoidal endothelial cells is the main denatured collagen clearance receptor.	MRC1 MRC2	1.79e-06	2	47	2	17518370
Pubmed	Genetic variation in CFH predicts phenytoin-induced maculopapular exanthema in European-descent patients.	CFH CFHR4	1.79e-06	2	47	2	29288229
Pubmed	CD163 and CD206 expression define distinct macrophage subsets involved in active ANCA-associated glomerulonephritis.	MRC1 CD163	1.79e-06	2	47	2	36183584
Pubmed	Tumour extracellular vesicle-derived Complement Factor H promotes tumorigenesis and metastasis by inhibiting complement-dependent cytotoxicity of tumour cells.	CFH CFHR4	1.79e-06	2	47	2	33708358
Pubmed	The macrophage-related biomarkers sCD163 and sCD206 are released by different shedding mechanisms.	MRC1 CD163	1.79e-06	2	47	2	31242338
Pubmed	Serological survey of complement factor H in common laboratory and wild mice: a new third allotype.	CFH CFHR4	1.79e-06	2	47	2	2522412
Pubmed	Absence of complement factor H alters bone architecture and dynamics.	CFH CFHR4	1.79e-06	2	47	2	30107932
Pubmed	Murine Factor H Co-Produced in Yeast With Protein Disulfide Isomerase Ameliorated C3 Dysregulation in Factor H-Deficient Mice.	CFH CFHR4	1.79e-06	2	47	2	34054871
Pubmed	Ovarian cancer cell heparan sulfate 6-O-sulfotransferases regulate an angiogenic program induced by heparin-binding epidermal growth factor (EGF)-like growth factor/EGF receptor signaling.	HS6ST2 HS6ST1	1.79e-06	2	47	2	24563483
Pubmed	Biosynthesis of heparan sulphate with diverse structures and functions: two alternatively spliced forms of human heparan sulphate 6-O-sulphotransferase-2 having different expression patterns and properties.	HS6ST2 HS6ST1	1.79e-06	2	47	2	12492399
Pubmed	Distinct and separable roles of the complement system in factor H-deficient bone marrow chimeric mice with immune complex disease.	CFH CFHR4	1.79e-06	2	47	2	16597679
Pubmed	CD4-independent infection of astrocytes by human immunodeficiency virus type 1: requirement for the human mannose receptor.	MRC1 MRC2	1.79e-06	2	47	2	15047828
Pubmed	Factor H binding to PspC of Streptococcus pneumoniae increases adherence to human cell lines in vitro and enhances invasion of mouse lungs in vivo.	CFH CFHR4	1.79e-06	2	47	2	17562771
Pubmed	AAV Gene Augmentation of Truncated Complement Factor H Differentially Rescues Ocular Complement Dysregulation in a Mouse Model.	CFH CFHR4	1.79e-06	2	47	2	37471073
Pubmed	Aged complement factor H knockout mice kept in a clean barriered environment have reduced retinal pathology.	CFH CFHR4	1.79e-06	2	47	2	27397653
Pubmed	Complement Factor H Serum Levels Determine Resistance to Pneumococcal Invasive Disease.	CFH CFHR4	1.79e-06	2	47	2	26802141
Pubmed	Effect of Anti-C5a Therapy in a Murine Model of Early/Intermediate Dry Age-Related Macular Degeneration.	CFH CFHR4	1.79e-06	2	47	2	29392311
Pubmed	The critical role of complement alternative pathway regulator factor H in allergen-induced airway hyperresponsiveness and inflammation.	CFH CFHR4	1.79e-06	2	47	2	22174452
Pubmed	Expression of human complement factor H prevents age-related macular degeneration-like retina damage and kidney abnormalities in aged Cfh knockout mice.	CFH CFHR4	1.79e-06	2	47	2	25447048
Pubmed	Structure of the murine complement factor H gene.	CFH CFHR4	1.79e-06	2	47	2	2972715
Pubmed	Loss of Complement Factor H in Plasma Increases Endothelial Cell Migration.	CFH CFHR4	1.79e-06	2	47	2	28819420
Pubmed	Complement factor H genotypes impact risk of age-related macular degeneration by interaction with oxidized phospholipids.	CFH CFHR4	1.79e-06	2	47	2	22875704
Pubmed	Complement factor H deficiency combined with smoking promotes retinal degeneration in a novel mouse model.	CFH CFHR4	1.79e-06	2	47	2	34775843
Pubmed	O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.	ADAMTS17 SEMA5A THSD7B ADAMTS14	3.32e-06	75	47	4	20637190
Pubmed	The occurrence of three isoforms of heparan sulfate 6-O-sulfotransferase having different specificities for hexuronic acid adjacent to the targeted N-sulfoglucosamine.	HS6ST2 HS6ST1	5.36e-06	3	47	2	10644753
Pubmed	Human complement factor H-related protein 4 binds and recruits native pentameric C-reactive protein to necrotic cells.	CFH CFHR4	5.36e-06	3	47	2	19084272
Pubmed	Complement factor H deficiency accelerates development of lupus nephritis.	CFH CFHR4	5.36e-06	3	47	2	21148254
Pubmed	HIV-1 interaction with human mannose receptor (hMR) induces production of matrix metalloproteinase 2 (MMP-2) through hMR-mediated intracellular signaling in astrocytes.	MRC1 MRC2	5.36e-06	3	47	2	15955449
Pubmed	Complement factor H protects mice from ischemic acute kidney injury but is not critical for controlling complement activation by glomerular IgM.	CFH CFHR4	5.36e-06	3	47	2	29389016
Pubmed	Prevention of Fatal C3 Glomerulopathy by Recombinant Complement Receptor of the Ig Superfamily.	CFH CFHR4	5.36e-06	3	47	2	29895552
Pubmed	Targeted inhibition of the complement alternative pathway with complement receptor 2 and factor H attenuates collagen antibody-induced arthritis in mice.	CFH CFHR4	5.36e-06	3	47	2	19828624
Pubmed	Structural polymorphism of murine complement factor H controlled by a locus located between the Hc and the beta 2M locus on the second chromosome of the mouse.	CFH CFHR4	5.36e-06	3	47	2	3156187
Pubmed	Lack of adrenomedullin, but not complement factor H, results in larger infarct size and more extensive brain damage in a focal ischemia model.	CFH CFHR4	5.36e-06	3	47	2	20854881
Pubmed	Uncontrolled C3 activation causes membranoproliferative glomerulonephritis in mice deficient in complement factor H.	CFH CFHR4	5.36e-06	3	47	2	12091909
Pubmed	Synergistic effects of ADAMTS13 deficiency and complement activation in pathogenesis of thrombotic microangiopathy.	CFH CFHR4	5.36e-06	3	47	2	31409673
Pubmed	Borrelia burgdorferi binding of host complement regulator factor H is not required for efficient mammalian infection.	CFH CFHR4	5.36e-06	3	47	2	17420242
Cytoband	4q35.2	DUX4L2 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7	2.41e-13	27	47	6	4q35.2
Cytoband	Ensembl 112 genes in cytogenetic band chr4q35	DUX4L2 DUX4 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7 DUX4L9	4.04e-13	117	47	8	chr4q35
Cytoband	16p13.11	NPIPA1 NPIPA3 NPIPA5	1.76e-06	23	47	3	16p13.11
Cytoband	Ensembl 112 genes in cytogenetic band chr16p13	NPIPA1 NPIPA3 NPIPA7 NPIPB2 NPIPA5	7.48e-05	426	47	5	chr16p13
Cytoband	1q32	CFH CFHR4	1.17e-03	49	47	2	1q32
Cytoband	14q32.33	IGHV3-35 IGHV5-51 IGHV4-28	1.67e-03	228	47	3	14q32.33
Cytoband	Ensembl 112 genes in cytogenetic band chr1q31	CFH CFHR4	2.71e-03	75	47	2	chr1q31
Cytoband	9q34.3	EGFL7 MAMDC4	5.33e-03	106	47	2	9q34.3
GeneFamily	PRD class homeoboxes and pseudogenes	DUX4L2 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7 DUX4L9	1.30e-10	92	30	7	521
GeneFamily	C-type lectin domain family	MRC1 MRC2 ASGR2	6.36e-05	47	30	3	494
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	CFH BCAN CFHR4	1.14e-04	57	30	3	1179
GeneFamily	ADAM metallopeptidases with thrombospondin type 1 motif	ADAMTS17 ADAMTS14	4.47e-04	19	30	2	50
GeneFamily	C2-set domain containing\|Immunoglobulin like domain containing\|Scavenger receptors	MRC1 CD163	9.10e-04	27	30	2	1253
GeneFamily	Complement system\|Sushi domain containing	CFH CFHR4	1.62e-03	36	30	2	492
GeneFamily	Sulfotransferases, membrane bound	HS6ST2 HS6ST1	1.71e-03	37	30	2	763
GeneFamily	Immunoglobulin heavy locus at 14q32.33	IGHV3-35 IGHV5-51 IGHV4-28	3.60e-03	187	30	3	349
GeneFamily	Proteases, serine	PRSS12 PRSS36	4.88e-03	63	30	2	738
GeneFamily	ADAM metallopeptidase domain containing\|CD molecules	MRC1 MRC2 CD163	2.70e-02	394	30	3	471
ToppCell	CV-Mild-6\|Mild / Virus stimulation, Condition and Cluster	NPIPA1 ZNF106 BCAN MRC2 PRSS36	5.62e-07	175	41	5	c4d530dbb37942427c9cd0a1533faeb6a3a45381
ToppCell	Bronchus_Control_(B.)-Immune-TX-MoAM-2\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	MRC1 EGFL7 PRSS36 GAA CD163	1.06e-06	199	41	5	fb63885273d906a85fef178d859d20a311eb8a72
ToppCell	primary_visual_cortex-Non-neuronal-macrophage-Macrophage-PVM_Mrc1\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	CFH MRC1 ASGR2 CD163	6.20e-06	130	41	4	3a0846b74ba34bd0e2a05b4f1f39f3940df93780
ToppCell	droplet-Pancreas-Exocrine-18m-Hematologic-leukocyte\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH MRC1 ASGR2 CD163	8.80e-06	142	41	4	bf4a9633d128805a0d7e426d6fe6c29db1ff8c81
ToppCell	frontal_cortex-Non-neuronal-macrophage-Macrophage-PVM_Mrc1\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	CFH MRC1 ASGR2 CD163	1.04e-05	148	41	4	d3ea907f8f408e9bb97ed223a3089e403e35f911
ToppCell	droplet-Fat-Gat-18m-Myeloid-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH MRC1 ASGR2 CD163	1.48e-05	162	41	4	052f797d8bcab8fc6a43e0bffdd215c88ee12889
ToppCell	5'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DUOX1 BCAN TMEM178B NPIPA5	1.71e-05	168	41	4	948d9e9972bd2a4b503d55fa69b70dd568a35a67
ToppCell	E18.5-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CFH MRC1 ASGR2 CD163	1.79e-05	170	41	4	6ec0cf055ae55e9fac147f7989c47f83ab07270c
ToppCell	facs-Brain_Myeloid-Cerebellum-3m-Myeloid-nan\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH MRC1 ZNF106 CD163	1.91e-05	173	41	4	869da6a65d1b9b7529c666ec44e3c8ddec2ea408
ToppCell	facs-Brain_Myeloid-Cerebellum-3m-Myeloid\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH MRC1 ZNF106 CD163	1.91e-05	173	41	4	0672bd8a4a9d18af343d01f09253fb3388896c10
ToppCell	facs-Brain_Myeloid-Cerebellum-3m\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH MRC1 ZNF106 CD163	1.91e-05	173	41	4	870e091ec30be01a900e1cb8b9ef1880e3b7b50d
ToppCell	PND07-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CFH MRC1 ASGR2 CD163	2.00e-05	175	41	4	d983e80eeb11f341c564ea684e2b0b585a90ae58
ToppCell	PND07-Immune-Immune_Myeloid-Monocytic-Macrophage-IM\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CFH MRC1 ASGR2 CD163	2.19e-05	179	41	4	fae869fb0a91428481bf8a9c111dcc639e2b4278
ToppCell	myeloid-macrophage\|myeloid / Lineage and Cell class	MRC1 EGFL7 THSD7B CD163	2.71e-05	189	41	4	7c7dc5361250d6848c4050f8ef995561a0984a44
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-Radial_glial-gliogenic/outer_RGCs_and_astrocytes\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	SEMA5A BCAN MRC2 HS6ST2	3.00e-05	194	41	4	7c6c0376603e5fcb64814fd6204d153629c2fbf5
ToppCell	Monocytes-M2-like_CD16+_macrophages\|World / Immune cells in Kidney/Urine in Lupus Nephritis	MRC1 EGFL7 GAA CD163	3.06e-05	195	41	4	10fa47bdcf6c9784ea930b75a5861e139421feed
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Club\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DUOX1 PRSS12 HS6ST2 PRSS36	3.12e-05	196	41	4	ed76eeb37400ca154feae9b7ebaddb6c434f8b81
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Neuronal-IN_Progenitors\|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.	SEMA5A BCAN MRC2 HS6ST2	3.24e-05	198	41	4	3811d9e3e54bbe8b208c591697e43b55ab5bbf0e
ToppCell	Tracheal-10x5prime-Stromal-Peri/Epineurial_-NAF_epineurial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	THSD7B ADAMTS14 GNRH1 MRC2	3.31e-05	199	41	4	fbec5c034576cb1adaf05f6f97cc5525d19e0c1b
ToppCell	10x_3'_v3-bone_marrow_(10x_3'_v3)-myeloid-myeloid_monocytic\|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	MRC1 ASGR2 GAA CD163	3.31e-05	199	41	4	7dde5c02fcae64cd2d68f607500f2a46b97851fd
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ADAMTS17 SEMA5A PRSS12 MRC2	3.31e-05	199	41	4	a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCell	10x_3'_v3-bone_marrow_(10x_3'_v3)-myeloid-myeloid_monocytic-monocyte\|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	MRC1 ASGR2 GAA CD163	3.31e-05	199	41	4	84879280851380e5bfe6bd48b6bbf57aedf6e003
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-6m\|organoid_Tanaka_cellReport / Sample Type, Dataset, Time_group, and Cell type.	CFH ZNF106 SEMA5A BCAN	3.37e-05	200	41	4	5ba4ed490c64b3bb738e7729669f893fa73aa56f
ToppCell	mLN-(6)_Macrophage-(61)_LYVE1_Macrophage\|mLN / shred on region, Cell_type, and subtype	MRC1 EGFL7 ASGR2 CD163	3.37e-05	200	41	4	a20f5ec61d492d8a2adf695ec304b5d57296aa8f
ToppCell	mLN-Macrophage-LYVE1_Macrophage\|mLN / Region, Cell class and subclass	MRC1 EGFL7 ASGR2 CD163	3.37e-05	200	41	4	89cf739a3c2f5d30e547404f2f2ec6500cd1d65d
ToppCell	Frontal_cortex-Hematopoietic-MACROPHAGE\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	MRC1 ASGR2 CD163	8.61e-05	93	41	3	1a112bd4e5e63826efad0338ce99d7a7ad9c72b9
ToppCell	Frontal_cortex-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)--\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	MRC1 ASGR2 CD163	8.61e-05	93	41	3	9c566fc2a8c7630bea28e8e46df55454aa409bc1
ToppCell	Frontal_cortex-Hematopoietic-MACROPHAGE-MP1(C1qb)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	MRC1 ASGR2 CD163	8.61e-05	93	41	3	d102a0a015a2866e3fe549ac8796b9a0d5923d7e
ToppCell	Frontal_cortex-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)-\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	MRC1 ASGR2 CD163	8.61e-05	93	41	3	0967a93dcc72d2d8f12d56de186ec1af55c36001
ToppCell	Frontal_cortex-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	MRC1 ASGR2 CD163	8.61e-05	93	41	3	613c827a643a7b6d70ef932cfa1762e90bc5a338
ToppCell	Entopeduncular-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Ccnd1_(Mural.Rgs5Acta2.Ccnd1)\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	MRC1 ADAMTS14 CD163	8.89e-05	94	41	3	d78535a7a0fda7299b01912333b944dc5e0a0361
ToppCell	Entopeduncular-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Ccnd1_(Mural.Rgs5Acta2.Ccnd1)-\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	MRC1 ADAMTS14 CD163	8.89e-05	94	41	3	dfc3f7977b9df433009d1d2d465b64a2de5806e2
ToppCell	Globus_pallidus-Hematopoietic-MACROPHAGE\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	MRC1 ASGR2 CD163	1.01e-04	98	41	3	fcb9da8b676f57facfdfc0ccaca585acaa6396f2
ToppCell	Globus_pallidus-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	MRC1 ASGR2 CD163	1.01e-04	98	41	3	dd6e81120ff27961da766f47a251688ee8390b90
ToppCell	Globus_pallidus-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)-\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	MRC1 ASGR2 CD163	1.01e-04	98	41	3	8ff05867d623fa13c361789fe76634ce1f4a9354
ToppCell	Globus_pallidus-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)--\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	MRC1 ASGR2 CD163	1.01e-04	98	41	3	0a4198a806cf9a143d546555f5e0bef2f2b6fd6e
ToppCell	Globus_pallidus-Hematopoietic-MACROPHAGE-MP1(C1qb)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	MRC1 ASGR2 CD163	1.01e-04	98	41	3	7e24ebfe74d1bd6af78b0b9d7c10852d49f85cf9
ToppCell	Thalamus-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)--\|Thalamus / BrainAtlas - Mouse McCarroll V32	MRC1 ASGR2 CD163	1.46e-04	111	41	3	a1b7940c6fa0e5a58aa4798b604469d79f33fa44
ToppCell	Thalamus-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)-\|Thalamus / BrainAtlas - Mouse McCarroll V32	MRC1 ASGR2 CD163	1.46e-04	111	41	3	d1ec8e8e9adb11511b4ef363cc6f99286e2cc842
ToppCell	Thalamus-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)\|Thalamus / BrainAtlas - Mouse McCarroll V32	MRC1 ASGR2 CD163	1.46e-04	111	41	3	567e5ac2c78d45db207067f0f152bb24ed048c50
ToppCell	Thalamus-Hematopoietic-MACROPHAGE-MP1(C1qb)\|Thalamus / BrainAtlas - Mouse McCarroll V32	MRC1 ASGR2 CD163	1.46e-04	111	41	3	fd7aa25e83a0d762969e3966a658652da40c490e
ToppCell	Thalamus-Hematopoietic-MACROPHAGE\|Thalamus / BrainAtlas - Mouse McCarroll V32	MRC1 ASGR2 CD163	1.46e-04	111	41	3	d48561078c387ac856c1c30e3d7a3e75ebde942e
ToppCell	Hippocampus-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	MRC1 ASGR2 CD163	1.53e-04	113	41	3	d5f183263cec9922d23cfd38ce9157eef4e58edb
ToppCell	Hippocampus-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)--\|Hippocampus / BrainAtlas - Mouse McCarroll V32	MRC1 ASGR2 CD163	1.53e-04	113	41	3	1df80af2c690dac6bfd3dfd7d0052b66c1ae6ea5
ToppCell	Hippocampus-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	MRC1 ASGR2 CD163	1.53e-04	113	41	3	177414e4c859b047a4644664c596a3c22199cdf2
ToppCell	Hippocampus-Hematopoietic-MACROPHAGE-MP1(C1qb)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	MRC1 ASGR2 CD163	1.53e-04	113	41	3	4b5f545dc02364c5d96a02b0acd68faf1ec4192b
ToppCell	Hippocampus-Hematopoietic-MACROPHAGE\|Hippocampus / BrainAtlas - Mouse McCarroll V32	MRC1 ASGR2 CD163	1.53e-04	113	41	3	927d1071f0719b778f0c3d358c5f96a6ffac6645
ToppCell	Striatum-Hematopoietic-MACROPHAGE\|Striatum / BrainAtlas - Mouse McCarroll V32	MRC1 ASGR2 CCER1	1.74e-04	118	41	3	54930a3faa055bda4a707b93d790b2ac5a360211
ToppCell	Striatum-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)\|Striatum / BrainAtlas - Mouse McCarroll V32	MRC1 ASGR2 CCER1	1.74e-04	118	41	3	18f9c1759df9504962612ec741638ed330c33222
ToppCell	Striatum-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)-\|Striatum / BrainAtlas - Mouse McCarroll V32	MRC1 ASGR2 CCER1	1.74e-04	118	41	3	97db1193ecc885f63840663ab969468ce21cba74
ToppCell	Striatum-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)--\|Striatum / BrainAtlas - Mouse McCarroll V32	MRC1 ASGR2 CCER1	1.74e-04	118	41	3	0c2fe46dd66e0c9cdf8c2eb66874aca79592248a
ToppCell	Striatum-Hematopoietic-MACROPHAGE-MP1(C1qb)\|Striatum / BrainAtlas - Mouse McCarroll V32	MRC1 ASGR2 CCER1	1.74e-04	118	41	3	3f8d11e09a7660af9eca5249ad698d9b638d39dd
ToppCell	COVID-19-kidney-Epithelial_(Imm)\|kidney / Disease (COVID-19 only), tissue and cell type	MRC1 NPIPB2 CD163	1.83e-04	120	41	3	e17c85d41c781a29dec7e03a8b0637dccb4346bc
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1-Airway\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DUOX1 THSD7B PRSS36	2.12e-04	126	41	3	cde3b0fbdc324120e45e295eb171ee550653de47
ToppCell	PND01-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_G2M\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MRC1 C2orf69 CD163	3.01e-04	142	41	3	be63c48794a227ea55978524c0f5935342fc455e
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c08-GZMK-FOS_h\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	PRSS12 HYAL3 SERGEF	3.26e-04	146	41	3	deeb2c90a478deac7805e1f0d1466bf5bc42f746
ToppCell	facs-Diaphragm-Limb_Muscle-18m-Myeloid-nan\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MRC1 ASGR2 CD163	3.26e-04	146	41	3	69cbe8d4772f8e46a5e1a1cdca0e370308a97b4f
ToppCell	droplet-Pancreas-Exocrine-18m-Hematologic\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MRC1 ASGR2 CD163	3.33e-04	147	41	3	684e2d8d2f0516cf8b0dc53efa7efc3050bbf0d1
ToppCell	droplet-Pancreas-Exocrine-18m-Hematologic-leukocyte\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MRC1 ASGR2 CD163	3.33e-04	147	41	3	c031fad0a4e192019775809968e46da54a111d27
ToppCell	facs-Pancreas-Exocrine-3m-Hematologic-leukocyte\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH MRC1 CD163	3.39e-04	148	41	3	bbf4933582b50b3412c805de5ed137107c996236
ToppCell	facs-Pancreas-Exocrine-3m-Hematologic-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH MRC1 CD163	3.39e-04	148	41	3	6543860e3207a7de92a35bb6004be51287582f7a
ToppCell	facs-Pancreas-Exocrine-3m-Hematologic\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH MRC1 CD163	3.39e-04	148	41	3	79e376503a3f9504a1ec5af4a60a09cc80e19059
ToppCell	Posterior_cortex-Hematopoietic-MICROGLIA-MI1(C1qb)-Tmem119-MICROGLIA_Microglia.C1qb.Tmem119-Fos_(Microglia)-\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	MRC1 ASGR2 CD163	3.46e-04	149	41	3	406a5ccfedbf43543f0346ff7ef3ce1d15c38f29
ToppCell	Posterior_cortex-Hematopoietic-MICROGLIA-MI1(C1qb)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	MRC1 ASGR2 CD163	3.46e-04	149	41	3	34a3075af794052763fc7c4135f3031f89da5caa
ToppCell	Posterior_cortex-Hematopoietic-MICROGLIA-MI1(C1qb)-Tmem119\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	MRC1 ASGR2 CD163	3.46e-04	149	41	3	be698ecce34ddbdf57d08082b71268934675e74e
ToppCell	Posterior_cortex-Hematopoietic-MICROGLIA-MI1(C1qb)-Tmem119-MICROGLIA_Microglia.C1qb.Tmem119-Fos_(Microglia)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	MRC1 ASGR2 CD163	3.46e-04	149	41	3	183c77cc8f23b8406e7241a066cb684470002a3b
ToppCell	droplet-Fat-Scat-21m-Myeloid-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MRC1 ASGR2 CD163	3.60e-04	151	41	3	79827a76c675dcb82f59c0a45d0f962b02d5bfd6
ToppCell	facs-Marrow-T-cells-24m-Myeloid-monocyte_+_promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH MRC1 ASGR2	3.67e-04	152	41	3	d279592c501fca9cb474ad916fea32282e6969cb
ToppCell	facs-Marrow-T-cells-24m-Myeloid-promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH MRC1 ASGR2	3.67e-04	152	41	3	3b59143b2b4ee24eb6378f87ff568124193256e9
ToppCell	368C-Myeloid-Macrophage-FABP4+_Macrophage\|368C / Donor, Lineage, Cell class and subclass (all cells)	MRC1 PRSS36 GAA	3.74e-04	153	41	3	e0fbbfd4d13031412e0b985322c8b99c56eb7af5
ToppCell	Severe-B_naive-5\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	MAMDC4 GNRH1 HS6ST1	3.74e-04	153	41	3	44572f87d403e314050ab935d2cd676c33d9c287
ToppCell	367C-Myeloid-Macrophage-SPP1+_Macrophage_4\|367C / Donor, Lineage, Cell class and subclass (all cells)	MRC1 ASGR2 CD163	3.74e-04	153	41	3	3570dd844d6479425bf6f62129f88efa45553775
ToppCell	droplet-Fat-SCAT-30m-Myeloid\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH MRC1 ASGR2	3.81e-04	154	41	3	73de626b210ec5482ba89a65e784c1e77ff2894e
ToppCell	droplet-Fat-SCAT-30m-Myeloid-myeloid_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH MRC1 ASGR2	3.81e-04	154	41	3	56fe9953e58f71626d3ddf63d340ed35dfc4ce9f
ToppCell	Smart-seq2-lymph_node_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte\|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	MRC1 ASGR2 CD163	3.81e-04	154	41	3	c6ecc46b99a783373729f7fae0b23216148ffb78
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_ALM_Cpa6\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SEMA5A THSD7B PRSS12	3.81e-04	154	41	3	12cbc38bc1f7231c67e1d2d5e86e95bc12e24682
ToppCell	10x5'-Liver-Myeloid_Mac-Intestinal_macrophages\|Liver / Manually curated celltypes from each tissue	MRC1 MRC2 CD163	3.96e-04	156	41	3	9a897fc79c4fae94c5f2e9012d65297f9225e5e3
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Myeloid-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MRC1 ASGR2 CD163	4.03e-04	157	41	3	c8f516d3f5622202d3f8514f68614cd86ea3f667
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Myeloid\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MRC1 ASGR2 CD163	4.03e-04	157	41	3	4862a11ab8df27d26b4f1c1785e544a2d5b6db6e
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Myeloid-macrophage\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MRC1 ASGR2 CD163	4.03e-04	157	41	3	a0ec1628ce29841889f1d9d4ee9422921af7b0b5
ToppCell	Severe-B_naive-5\|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)	MAMDC4 GNRH1 HS6ST1	4.03e-04	157	41	3	a57ee4a6febdff3ee3d1645836695e6e7c055cf8
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	NPIPA7 MRC2 HS6ST1	4.11e-04	158	41	3	1cefb82b9bf79c687a119be568cfc15b14c6e040
ToppCell	Children_(3_yrs)-Epithelial-basal_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CFH PRSS12 HS6ST2	4.11e-04	158	41	3	d78e7e52657dc094430291fec07e9c298be9e584
ToppCell	droplet-Lung-3m-Hematologic-myeloid-interstitial_macrophage\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MRC1 ASGR2 CD163	4.11e-04	158	41	3	9a6d9b541446a6aa9f8ed040b330dbb5c6447076
ToppCell	droplet-Lung-3m-Hematologic-myeloid-interstitial_macrophage-interstitial_macrophage_l12\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MRC1 ASGR2 CD163	4.11e-04	158	41	3	2438713d2a7e32c647ab3384237ed614f4ec8fec
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c5-CD16\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	EGFL7 ASGR2 CD163	4.18e-04	159	41	3	210ac7fa89514a84f38d9f42254e38fbc2bc5f42
ToppCell	NS-critical-d_16-33-Myeloid-Mast_cell\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	EGFL7 ADAMTS14 HS6ST1	4.26e-04	160	41	3	c61869d9dbba250270e59366e15af204e5b4395d
ToppCell	droplet-Fat-SCAT-30m-Myeloid-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH MRC1 ASGR2	4.26e-04	160	41	3	61eefe84c8e30d8a3812f5b48d26ed01739aa1ce
ToppCell	droplet-Lung-nan-3m-Myeloid-Interstitial_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MRC1 ASGR2 CD163	4.34e-04	161	41	3	f1d3287d9cb4e0eec99b3509f5dc4b87ae8c8cc9
ToppCell	droplet-Fat-Mat-18m-Myeloid-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MRC1 ASGR2 CD163	4.34e-04	161	41	3	8c62ae3fcf304db0f71633e328ceba81a70f03c4
ToppCell	droplet-Lung-nan-3m-Myeloid-lung_macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MRC1 ASGR2 CD163	4.34e-04	161	41	3	110cc7122e3c9f105a11d811d77c8a8852b9de6c
ToppCell	5'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell-SMG_duct\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFH DMBT1 HYAL3	4.50e-04	163	41	3	a1fbefe53523a9879a4d4b493071059798b5f917
ToppCell	5'-Airway_Nasal_SMG-Epithelial\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFH DMBT1 HYAL3	4.50e-04	163	41	3	454a5e87e2f9f66e38cc5aa1b433c47b54c9be42
ToppCell	5'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFH DMBT1 HYAL3	4.50e-04	163	41	3	d9bd9d90cfa4e85d5ea51f8f3ee14a700571f508
ToppCell	5'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFH DMBT1 HYAL3	4.50e-04	163	41	3	f6847f47a8856c0d4136c1af317432d45eccfde9
ToppCell	E16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-Mature_Fibroblast_1\|E16.5-samps / Age Group, Lineage, Cell class and subclass	ADAMTS17 CFH MRC2	4.50e-04	163	41	3	f1ec2625b52664308968b01d8e0275e1e0751480
ToppCell	5'-Airway_Nasal_SMG\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFH DMBT1 HYAL3	4.50e-04	163	41	3	d8450bf9c6d2ec5dd1472952c9e65f82f995337a
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell-Degenerative_Peritubular_Capilary_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NPIPA3 EGFL7 NPIPA7	4.50e-04	163	41	3	73c03e29a6d7a6863c5e9aa5e8b963ef691f1ddb
ToppCell	5'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell-SMG_duct-SMG_duct_L.0.6.2.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFH DMBT1 HYAL3	4.50e-04	163	41	3	be6cc44df9a2b10dce1a353717c279c3558f8fec
ToppCell	NS-moderate-d_16-33-Myeloid-Mast_cell\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	BCAN EGFL7 ADAMTS14	4.58e-04	164	41	3	35c673380f75cb4bfe080089bc723c4373bcc7a5
Computational	Neighborhood of IGFBP1	CFH ASGR2 CFHR4	1.09e-04	57	18	3	CAR_IGFBP1
Computational	Neighborhood of HPX	CFH ASGR2 CFHR4	2.28e-04	73	18	3	CAR_HPX
Drug	estradiol 17 beta-cypionate	MRC1 GNRH1 CD163	8.15e-06	22	41	3	ctd:C007630
Disease	c3d:C3 ratio	CFH CFHR4	1.29e-06	2	34	2	EFO_0008543
Disease	calnexin measurement	CFH CFHR4	3.86e-06	3	34	2	EFO_0801444
Disease	complement factor H-related protein 4A measurement	CFH CFHR4	3.86e-06	3	34	2	EFO_0600057
Disease	brevican core protein measurement	CFH BCAN	3.86e-06	3	34	2	EFO_0020193
Disease	histone-lysine N-methyltransferase 2D measurement	CFH CFHR4	3.86e-06	3	34	2	EFO_0801683
Disease	NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial measurement	CFH CFHR4	7.72e-06	4	34	2	EFO_0803292
Disease	semaphorin-6A measurement	CFH MRC1	7.72e-06	4	34	2	EFO_0020721
Disease	kallikrein-5 measurement	CFH CFHR4	7.72e-06	4	34	2	EFO_0020515
Disease	complement C1s subcomponent measurement	CFH CFHR4	1.93e-05	6	34	2	EFO_0008091
Disease	pleckstrin homology domain-containing family A member 1 measurement	CFH DMBT1	2.70e-05	7	34	2	EFO_0802873
Disease	Atypical hemolytic-uremic syndrome	CFH CFHR4	4.62e-05	9	34	2	cv:C2931788
Disease	Hemolytic-uremic syndrome	CFH CFHR4	4.62e-05	9	34	2	cv:C0019061
Disease	leukocyte immunoglobulin-like receptor subfamily A member 5 measurement	CFH CFHR4	4.62e-05	9	34	2	EFO_0801766
Disease	non-receptor tyrosine-protein kinase TYK2 measurement	CFH EGFL7	5.77e-05	10	34	2	EFO_0008251
Disease	hemopexin measurement	CFH CFHR4	7.04e-05	11	34	2	EFO_0008149
Disease	coagulation factor measurement	CFH CFHR4	2.42e-04	20	34	2	EFO_0004634
Disease	energy expenditure measurement	THSD7B SERGEF	2.42e-04	20	34	2	EFO_0008005
Disease	L lactate dehydrogenase measurement	CFH CD163	4.12e-04	26	34	2	EFO_0004808
Disease	Endogenous Hyperinsulinism	MRC1 CD163	4.12e-04	26	34	2	C1257963
Disease	Exogenous Hyperinsulinism	MRC1 CD163	4.12e-04	26	34	2	C1257964
Disease	Compensatory Hyperinsulinemia	MRC1 CD163	4.12e-04	26	34	2	C1257965
Disease	uromodulin measurement	CFH ASGR2	4.12e-04	26	34	2	EFO_0021778
Disease	Hyperinsulinism	MRC1 CD163	4.78e-04	28	34	2	C0020459
Disease	complement factor H-related protein 2 measurement	CFH CFHR4	5.13e-04	29	34	2	EFO_0600055
Disease	Age related macular degeneration	CFH CFHR4	5.49e-04	30	34	2	C0242383
Disease	photoreceptor cell layer thickness measurement	DUOX1 DMBT1 CFHR4	6.60e-04	148	34	3	EFO_0803370
Disease	Complement deficiency disease	CFH CFHR4	6.65e-04	33	34	2	C0272242
Disease	complement factor H measurement	CFH CFHR4	1.03e-03	41	34	2	EFO_0008097
Disease	complement factor H-related protein 5 measurement	CFH CFHR4	1.08e-03	42	34	2	EFO_0008098

Protein segments in the cluster

Peptide	Gene	Start	Entry
DTCSWYPGHLSDTHW	MAMDC4	661	Q6UXC1
AGSYWCQCWEGHSLS	EGFL7	156	Q9UHF1
MYWLDGGHSGGSNTW	C2orf69	296	Q8N8R5
GSCYWFSHSGKAWAE	ASGR2	186	P07307
SWVAFAHTGAWGTGL	DUX4L4	176	P0CJ87
GSYWDHIHCTQDGWS	CFH	366	P08603
SWVAFAHTGAWGTGL	DUX4L6	176	P0CJ89
HACGWGWVTHATYGE	C1orf147	141	Q96MC9
GCGCGWAHSASLSSW	CCER1	21	Q8TC90
QDGGWSSWTKFGSCS	ADAMTS14	551	Q8WXS8
SGCYEWKTGDWSTCS	ADAMTS17	971	Q8TE56
GYEWLSGGCKTWHSA	NPIPA1	6	Q9UND3
GWLDGSAIYGSSHSW	DUOX1	171	Q9NRD9
YAAWDGGLDHCSPGW	BCAN	291	Q96GW7
YASGVWGTVCSSHWD	PRSS12	186	P56730
SWVAFAHTGAWGTGL	DUX4	176	Q9UBX2
SWVAFAHTGAWGTGL	DUX4L3	176	P0CJ86
GQSWRWSDGVGFSYH	MRC2	756	Q9UBG0
CAVSGYSISSSNWWG	IGHV4-28	41	A0A0C4DH34
GYEWLSGGCKTWHSA	NPIPA3	6	F8WFD2
FSTGWSCGLHADWTE	HS6ST1	141	O60243
CKGSGYSFTSYWIGW	IGHV5-51	41	A0A0C4DH38
RFVHGTACWATGWGD	PRSS36	166	Q5K4E3
SWVAFAHTGAWGTGL	DUX4L9	176	Q6RFH8
SLGDWKSFSCHCYWG	HYAL3	386	O43820
KSFSCHCYWGWAGPT	HYAL3	391	O43820
SWVAFAHTGAWGTGL	DUX4L7	176	P0CJ90
SGSYWDYIHCTQDGW	CFHR4	311	Q92496
YWGLGFHLCRWGYSS	GAA	366	P10253
FSTGWSCGLHADWTE	HS6ST2	281	Q96MM7
WCVEGCSSQHWSYGL	GNRH1	16	P01148
SWVAFAHTGAWGTGL	DUX4L5	176	P0CJ88
TSCSGRVEIWHGGSW	CD163	936	Q86VB7
HGGSWGTVCDDSWDL	CD163	946	Q86VB7
SGHESYLWSCPHNGW	DMBT1	1321	Q9UGM3
IYHGGTWGTVCDDSW	DMBT1	1901	Q9UGM3
WYHSHPGFGCWLSGV	PSMD14	111	O00487
WVSGVSWNGSRTHYA	IGHV3-35	66	A0A0C4DH35
GRSDGWLWCGTTTDY	MRC1	186	P22897
GYEWLSGGCTTWHSA	NPIPA7	6	E9PJI5
GYEWLSGGCTTWHSA	NPIPA8	6	P0DM63
GVCYSWGWNEHGMCG	SERGEF	351	Q9UGK8
HGYGWSMFCAWGGLG	TMEM178B	246	H3BS89
GYEWLSGGCKTWHSA	NPIPA5	6	E9PKD4
WTTCGLSKDGYGGWQ	RNF215	221	Q9Y6U7
GRYSAHTVNGAWSAW	SEMA5A	776	Q13591
GYEWLSGGCKTWHSA	NPIPB2	6	A6NJ64
WSSWGSCSSSCGIGV	THSD7B	1006	Q9C0I4
SGWHKGVAGGSSTWF	ZNF106	161	Q9H2Y7
VWECSAGHTFSWGPS	ZNF692	111	Q9BU19
SWVAFAHTGAWGTGL	DUX4L2	176	P0CJ85