Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

KCNA1 KCNA2 KCND2

7.54e-0661463GO:1905030
GeneOntologyMolecularFunctionoutward rectifier potassium channel activity

KCNA2 KCNA5 KCND2 KCND3

4.22e-05271464GO:0015271
GeneOntologyMolecularFunctiondelayed rectifier potassium channel activity

KCNA1 KCNA2 KCNA5 KCNA7

4.90e-05281464GO:0005251
GeneOntologyMolecularFunctionphosphatidylserine transfer activity

OSBPL5 OSBPL8

5.31e-0521462GO:0140343
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity

GRIN2B KCNA1 KCNA2 KCNA5 CLCN3 KCNA7 KCND2 KCND3

5.90e-051821468GO:0005244
GeneOntologyMolecularFunctiontransporter activity

SLC6A16 SLC5A9 ABCC5 SLCO1B3 GRIN2B SLCO6A1 SLC9C2 AQP6 SLC2A2 KCNA1 KCNA2 KCNA5 CLCN3 KCNA7 SLC16A1 KCND2 KCND3 SLC9B2 OSBPL5 OSBPL8 SLC25A29 SLC29A4 SLC26A6

6.14e-05128914623GO:0005215
GeneOntologyMolecularFunctionvoltage-gated channel activity

GRIN2B KCNA1 KCNA2 KCNA5 CLCN3 KCNA7 KCND2 KCND3

6.37e-051841468GO:0022832
GeneOntologyMolecularFunctionvoltage-gated potassium channel activity

KCNA1 KCNA2 KCNA5 KCNA7 KCND2 KCND3

1.04e-041021466GO:0005249
GeneOntologyMolecularFunctionmismatched DNA binding

TDG MSH2 MSH4

1.31e-04141463GO:0030983
GeneOntologyMolecularFunctiontransmembrane transporter activity

SLC6A16 SLC5A9 ABCC5 SLCO1B3 GRIN2B SLCO6A1 SLC9C2 AQP6 SLC2A2 KCNA1 KCNA2 KCNA5 CLCN3 KCNA7 SLC16A1 KCND2 KCND3 SLC9B2 SLC25A29 SLC29A4 SLC26A6

1.38e-04118014621GO:0022857
GeneOntologyMolecularFunctionefflux transmembrane transporter activity

ABCC5 SLC29A4 SLC26A6

2.00e-04161463GO:0015562
GeneOntologyMolecularFunctionpotassium ion transmembrane transporter activity

SLC9C2 KCNA1 KCNA2 KCNA5 KCNA7 KCND2 KCND3

2.31e-041671467GO:0015079
GeneOntologyMolecularFunctionA-type (transient outward) potassium channel activity

KCND2 KCND3

3.16e-0441462GO:0005250
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC6A16 SLC5A9 SLCO1B3 SLCO6A1 SLC9C2 CLCN3 SLC16A1 SLC9B2 SLC26A6

3.36e-042961469GO:0015291
GeneOntologyMolecularFunctionATP-dependent activity, acting on DNA

RAD51B RECQL MSH2 MSH4 ZRANB3 RUVBL1

3.45e-041271466GO:0008094
GeneOntologyMolecularFunctionpotassium channel activity

KCNA1 KCNA2 KCNA5 KCNA7 KCND2 KCND3

3.60e-041281466GO:0005267
GeneOntologyMolecularFunctionATP-dependent DNA damage sensor activity

RAD51B MSH2 MSH4

3.98e-04201463GO:0140664
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

SLC5A9 ABCC5 GRIN2B SLC9C2 AQP6 KCNA1 KCNA2 KCNA5 CLCN3 KCNA7 SLC16A1 KCND2 KCND3 SLC9B2 SLC26A6

4.49e-0475814615GO:0015318
GeneOntologyMolecularFunctionCoA-transferase activity

OXCT1 SUGCT

5.23e-0451462GO:0008410
GeneOntologyMolecularFunctionscaffold protein binding

SHANK1 GRIN2B CIT KCNA5 NOS3

6.05e-04931465GO:0097110
GeneOntologyMolecularFunctionDNA damage sensor activity

RAD51B MSH2 MSH4

6.92e-04241463GO:0140612
GeneOntologyMolecularFunctionactive transmembrane transporter activity

SLC6A16 SLC5A9 ABCC5 SLCO1B3 SLCO6A1 SLC9C2 CLCN3 SLC16A1 SLC9B2 SLC29A4 SLC26A6

7.81e-0447714611GO:0022804
GeneOntologyMolecularFunctionvoltage-gated monoatomic cation channel activity

KCNA1 KCNA2 KCNA5 KCNA7 KCND2 KCND3

8.91e-041521466GO:0022843
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

ABCC5 SLCO1B3 GRIN2B SLCO6A1 SLC2A2 SLC16A1 SLC25A29 SLC26A6

1.44e-032931468GO:0008514
GeneOntologyMolecularFunctionligase activity

RTCB GART CPS1 PARS2 ACSF3 PCCA

1.78e-031741466GO:0016874
GeneOntologyMolecularFunctionATP-dependent activity

RAD51B LONP2 HSPH1 ABCC5 RECQL MSH2 MSH4 ZRANB3 MYO5C RUVBL1 ACSF3 HSPA8

1.87e-0361414612GO:0140657
GeneOntologyMolecularFunctionamino acid binding

GRIN2B CPS1 OTC NOS3

2.02e-03731464GO:0016597
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

SLC5A9 GRIN2B SLC9C2 KCNA1 KCNA2 KCNA5 CLCN3 KCNA7 SLC16A1 KCND2 KCND3 SLC9B2 SLC29A4 SLC26A6

2.06e-0379314614GO:0015075
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

SLC5A9 GRIN2B SLC9C2 KCNA1 KCNA2 KCNA5 KCNA7 KCND2 KCND3 SLC9B2

2.26e-0346514610GO:0046873
GeneOntologyBiologicalProcessprotein homooligomerization

ALS2 KCTD21 KCNA1 KCNA2 PXDN KCNA5 KCNA7 KCND2 KCND3 C9

4.56e-0622414610GO:0051260
GeneOntologyBiologicalProcessprotein complex oligomerization

ALS2 KCTD21 GRIN2B KCNA1 KCNA2 PXDN KCNA5 KCNA7 KCND2 KCND3 C9

8.69e-0629614611GO:0051259
GeneOntologyBiologicalProcessaction potential

NPR2 NRCAM GRIN2B KCNA1 KCNA2 KCNA5 KCNA7 KCND2 KCND3

1.35e-052011469GO:0001508
GeneOntologyBiologicalProcesscitrulline metabolic process

CPS1 OTC HTT

2.83e-0591463GO:0000052
GeneOntologyBiologicalProcessmembrane repolarization

ADCY10 KCNA1 KCNA5 KCND2 KCND3

4.74e-05561465GO:0086009
GeneOntologyBiologicalProcessplasma membrane bounded cell projection morphogenesis

SHANK1 ADCY10 SEMA4D NPR2 NRCAM ALS2 CIT IQGAP1 BCL11B CSF1R PLPPR4 NFATC4 ARHGEF7 STAU2 CDC42 TNR MAP4K4

7.05e-0581914617GO:0120039
GeneOntologyBiologicalProcesscell projection morphogenesis

SHANK1 ADCY10 SEMA4D NPR2 NRCAM ALS2 CIT IQGAP1 BCL11B CSF1R PLPPR4 NFATC4 ARHGEF7 STAU2 CDC42 TNR MAP4K4

7.83e-0582614617GO:0048858
GeneOntologyBiologicalProcessurea cycle

CPS1 OTC HTT

9.43e-05131463GO:0000050
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

TCN2 SLC6A16 SLC5A9 ABCC5 GRIN2B SLC9C2 AQP6 KCNA1 KCNA2 KCNA5 CLCN3 KCNA7 SLC16A1 KCND2 KCND3 CNKSR3 SLC9B2 SLC26A6 HTT

1.05e-04101714619GO:0098660
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

TCN2 SLC6A16 SLC5A9 ABCC5 GRIN2B SLC9C2 KCNA1 KCNA2 KCNA5 CLCN3 KCNA7 SLC16A1 KCND2 KCND3 CNKSR3 SLC9B2 SLC29A4 HTT

1.22e-0494214618GO:0098655
GeneOntologyBiologicalProcessphagocytosis, engulfment

SIGLEC12 GSN SIGLEC7 CLCN3 CDC42

1.30e-04691465GO:0006911
GeneOntologyBiologicalProcesstransmission of nerve impulse

NPR2 NRCAM KCNA1 KCNA2 KCND2 TNR

1.47e-041121466GO:0019226
GeneOntologyBiologicalProcessurea metabolic process

CPS1 OTC HTT

1.49e-04151463GO:0019627
GeneOntologyBiologicalProcessnitrogen cycle metabolic process

CPS1 OTC HTT

1.49e-04151463GO:0071941
GeneOntologyBiologicalProcessneuron projection morphogenesis

SHANK1 ADCY10 SEMA4D NPR2 NRCAM ALS2 CIT IQGAP1 BCL11B CSF1R PLPPR4 NFATC4 STAU2 CDC42 TNR MAP4K4

1.83e-0480214616GO:0048812
GeneOntologyBiologicalProcesscell junction organization

SHANK1 SEMA4D IQSEC3 LRRN1 NRCAM ALS2 GRIN2B IQGAP1 ARHGAP6 CSF1R PLPPR4 NFATC4 ARHGEF7 STAU2 CDC42 TNR MAP4K4 HSPA8

1.85e-0497414618GO:0034330
GeneOntologyBiologicalProcessamide transport

ABCC5 SLCO1B3 SLC2A2 OXCT1 KCNA5 SLC16A1 ARHGEF7 SLC9B2 MAP4K4 SLC26A6 HTT

2.05e-0442014611GO:0042886
GeneOntologyBiologicalProcesssmall molecule catabolic process

ADCY10 LONP2 SCARF1 AGXT2 OTC OXCT1 SLC16A1 AASS ACSF3 PCCA NOS3

2.09e-0442114611GO:0044282
GeneOntologyBiologicalProcessplasma membrane invagination

SIGLEC12 GSN SIGLEC7 CLCN3 CDC42

2.31e-04781465GO:0099024
GeneOntologyBiologicalProcessactin filament-based process

SHANK1 ADCY10 IQSEC3 CIT GSN IQGAP1 MYO5C EHD2 ARHGAP6 CSF1R KCNA5 ARHGEF10 KCND3 ARHGEF7 STAU2 FHL3 CDC42

2.55e-0491214617GO:0030029
GeneOntologyBiologicalProcesscell morphogenesis involved in neuron differentiation

SHANK1 ADCY10 SEMA4D NPR2 NRCAM FAT3 ALS2 CIT BCL11B CSF1R PLPPR4 NFATC4 STAU2 CDC42 TNR

2.78e-0474814615GO:0048667
GeneOntologyBiologicalProcessinorganic cation transmembrane transport

TCN2 SLC6A16 SLC5A9 ABCC5 GRIN2B SLC9C2 KCNA1 KCNA2 KCNA5 CLCN3 KCNA7 SLC16A1 KCND2 KCND3 CNKSR3 SLC9B2 HTT

2.89e-0492214617GO:0098662
GeneOntologyBiologicalProcesscell morphogenesis

SHANK1 ADCY10 SEMA4D NPR2 NRCAM FAT3 VPS33A ALS2 CIT IQGAP1 BCL11B CSF1R PLPPR4 NFATC4 ARHGEF7 STAU2 CFAP44 CDC42 TNR MAP4K4

2.92e-04119414620GO:0000902
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

TCN2 SLC6A16 SLC5A9 ABCC5 GRIN2B SLC9C2 KCNA1 KCNA2 KCNA5 CLCN3 KCNA7 SLC16A1 KCND2 KCND3 CNKSR3 SLC9B2 SLC29A4 SLC26A6 HTT

3.38e-04111514619GO:0034220
GeneOntologyBiologicalProcesssynapse organization

SHANK1 SEMA4D IQSEC3 LRRN1 NRCAM ALS2 GRIN2B PLPPR4 NFATC4 ARHGEF7 STAU2 CDC42 TNR HSPA8

3.70e-0468514614GO:0050808
GeneOntologyBiologicalProcessmembrane invagination

SIGLEC12 GSN SIGLEC7 CLCN3 CDC42

3.85e-04871465GO:0010324
GeneOntologyBiologicalProcesspostsynapse organization

SHANK1 IQSEC3 NRCAM GRIN2B PLPPR4 ARHGEF7 STAU2 CDC42 HSPA8

4.00e-043131469GO:0099173
GeneOntologyBiologicalProcessvacuole organization

MBTPS1 NPR2 VPS33A BECN2 TFE3 WDR45 PIK3C3 HSPA8

4.06e-042491468GO:0007033
GeneOntologyBiologicalProcessnegative regulation of cellular component organization

SHANK1 SIGLEC12 FAT3 TFIP11 GRIN2B CIT GSN ARHGAP6 SIGLEC7 NFATC4 ARHGEF7 CDC42 TNR MAP4K4 HSPA8 VAT1

4.19e-0486414616GO:0051129
GeneOntologyBiologicalProcesspotassium ion export across plasma membrane

KCNA2 KCNA5 KCND3

4.21e-04211463GO:0097623
GeneOntologyBiologicalProcessregulation of anatomical structure size

ADCY10 SEMA4D NRCAM ALS2 CPS1 ITGA9 CIT GSN HP1BP3 KCNA5 CLCN3 TNR NOS3

4.60e-0461814613GO:0090066
GeneOntologyBiologicalProcessexport across plasma membrane

ABCC5 KCNA2 KCNA5 KCND3 SLC29A4

4.73e-04911465GO:0140115
GeneOntologyBiologicalProcessnegative regulation of phagocytosis, engulfment

SIGLEC12 SIGLEC7

4.91e-0451462GO:0060101
GeneOntologyBiologicalProcesspositive regulation of protein folding

POFUT2 HSPA8

4.91e-0451462GO:1903334
GeneOntologyBiologicalProcesscitrulline biosynthetic process

CPS1 OTC

4.91e-0451462GO:0019240
GeneOntologyBiologicalProcessmodulation by host of viral process

CSF1R PIK3C3 CDC42 HSPA8

5.01e-04521464GO:0044788
GeneOntologyBiologicalProcessmonoatomic cation transport

TCN2 SLC6A16 SLC5A9 ABCC5 GRIN2B SLC9C2 KCNA1 KCNA2 KCNA5 CLCN3 KCNA7 SLC16A1 KCND2 KCND3 CNKSR3 SLC9B2 NOS3 SLC29A4 HTT

5.33e-04115714619GO:0006812
GeneOntologyBiologicalProcesscellular catabolic process

ADCY10 MAGEA6 LONP2 VPS33A BECN2 CPS1 AGXT2 NLN WDR45 OTC OXCT1 PXDN SLC16A1 PIK3C3 AASS ACSF3 PCCA NOS3 HSPA8 HTT

5.41e-04125314620GO:0044248
GeneOntologyBiologicalProcessregulation of ARF protein signal transduction

IQSEC3 GRIN2B MAP4K4

5.55e-04231463GO:0032012
GeneOntologyBiologicalProcesspositive regulation by host of viral process

CSF1R PIK3C3 HSPA8

5.55e-04231463GO:0044794
GeneOntologyBiologicalProcessoligopeptide transport

ABCC5 SLCO1B3 SLC26A6

5.55e-04231463GO:0006857
GeneOntologyBiologicalProcessgamete generation

ADCY10 RHBDD1 NPR2 ADAMTS2 MSH2 MSH4 TDRD1 CIT RUVBL1 CFAP52 STAU2 PABPC1L CDC25C CFAP44 NOS3 SLC26A6 HTT

5.93e-0498214617GO:0007276
GeneOntologyBiologicalProcessamino acid metabolic process

GART CPS1 PARS2 AGXT2 OTC AASS PCCA NOS3 HTT

6.11e-043321469GO:0006520
GeneOntologyBiologicalProcessARF protein signal transduction

IQSEC3 GRIN2B MAP4K4

6.31e-04241463GO:0032011
GeneOntologyBiologicalProcessregulation of membrane potential

SHANK1 ADCY10 NPR2 NRCAM GRIN2B KCNA1 KCNA2 KCNA5 KCNA7 KCND2 KCND3 MTCH2

6.39e-0455914612GO:0042391
GeneOntologyBiologicalProcessdendrite development

SHANK1 SEMA4D FAT3 CIT IQGAP1 SCARF1 NFATC4 STAU2 CDC42

6.51e-043351469GO:0016358
GeneOntologyBiologicalProcessmonoatomic ion transport

TCN2 SLC6A16 SLC5A9 ABCC5 SLCO1B3 GRIN2B SLC9C2 KCNA1 KCNA2 KCNA5 CLCN3 KCNA7 SLC16A1 KCND2 KCND3 CNKSR3 SLC9B2 NOS3 SLC29A4 SLC26A6 HTT

6.85e-04137414621GO:0006811
GeneOntologyBiologicalProcessregulation of dendrite development

SEMA4D FAT3 CIT IQGAP1 NFATC4 STAU2

7.04e-041501466GO:0050773
GeneOntologyBiologicalProcessorganic acid catabolic process

LONP2 AGXT2 OTC SLC16A1 AASS ACSF3 PCCA NOS3

7.25e-042721468GO:0016054
GeneOntologyBiologicalProcesscarboxylic acid catabolic process

LONP2 AGXT2 OTC SLC16A1 AASS ACSF3 PCCA NOS3

7.25e-042721468GO:0046395
GeneOntologyBiologicalProcesspotassium ion transport

SLC9C2 KCNA1 KCNA2 KCNA5 KCNA7 KCND2 KCND3 NOS3

7.25e-042721468GO:0006813
GeneOntologyBiologicalProcessnegative regulation of membrane invagination

SIGLEC12 SIGLEC7

7.33e-0461462GO:1905154
GeneOntologyCellularComponentbasal part of cell

ADCY10 EPPK1 ABCC5 SLCO1B3 ITGA9 SLCO6A1 SLC2A2 IQGAP1 SLC16A1 MPP4 SLC9B2 SLC29A4 SLC26A6

3.04e-0637814813GO:0045178
GeneOntologyCellularComponentapical part of cell

ADCY10 PDZK1P1 ABCC5 AQP6 SLC2A2 IQGAP1 KCNA1 KCNA5 CLCN3 SLC16A1 CNKSR3 SLC9B2 CDC42 NOS3 SLC29A4 SLC26A6

4.83e-0659214816GO:0045177
GeneOntologyCellularComponentapical plasma membrane

ADCY10 PDZK1P1 ABCC5 AQP6 SLC2A2 IQGAP1 KCNA1 KCNA5 CLCN3 SLC16A1 CNKSR3 SLC9B2 SLC29A4 SLC26A6

9.82e-0648714814GO:0016324
GeneOntologyCellularComponentbasal plasma membrane

EPPK1 ABCC5 SLCO1B3 ITGA9 SLCO6A1 SLC2A2 IQGAP1 SLC16A1 SLC9B2 SLC29A4 SLC26A6

4.55e-0535414811GO:0009925
GeneOntologyCellularComponentvoltage-gated potassium channel complex

KCNA1 KCNA2 KCNA5 KCNA7 KCND2 KCND3

4.62e-05911486GO:0008076
GeneOntologyCellularComponentbasolateral plasma membrane

EPPK1 ABCC5 SLCO1B3 SLCO6A1 SLC2A2 IQGAP1 SLC16A1 SLC9B2 SLC29A4 SLC26A6

9.71e-0532014810GO:0016323
GeneOntologyCellularComponentpotassium channel complex

KCNA1 KCNA2 KCNA5 KCNA7 KCND2 KCND3

9.76e-051041486GO:0034705
GeneOntologyCellularComponentpostsynaptic membrane

SHANK1 IQSEC3 NRCAM GRIN2B KCNA1 KCNA2 CLCN3 PLPPR4 KCND2 KCND3 HSPA8

1.50e-0440514811GO:0045211
GeneOntologyCellularComponentGABA-ergic synapse

SEMA4D IQSEC3 CLCN3 KCND2 KCND3 PIK3C3 ARHGEF7

1.70e-041641487GO:0098982
GeneOntologyCellularComponentsynaptic membrane

SHANK1 IQSEC3 NRCAM GRIN2B KCNA1 KCNA2 CLCN3 PLPPR4 KCND2 KCND3 MPP4 HSPA8 HTT

2.65e-0458314813GO:0097060
GeneOntologyCellularComponentdistal axon

ADCY10 DCTN2 ALS2 GRIN2B IQGAP1 KCNA1 KCNA2 CLCN3 ARHGEF7 MPP4 HSPA8

2.78e-0443514811GO:0150034
GeneOntologyCellularComponentstorage vacuole

ARHGEF7 CDC42

2.96e-0441482GO:0000322
GeneOntologyCellularComponentphosphatidylinositol 3-kinase complex, class III, type II

BECN2 PIK3C3

2.96e-0441482GO:0034272
GeneOntologyCellularComponentphosphatidylinositol 3-kinase complex, class III, type I

BECN2 PIK3C3

2.96e-0441482GO:0034271
GeneOntologyCellularComponentphosphatidylinositol 3-kinase complex, class III

BECN2 PIK3C3

1.02e-0371482GO:0035032
GeneOntologyCellularComponentaxon initial segment

NRCAM KCNA1 KCNA2

1.11e-03291483GO:0043194
GeneOntologyCellularComponentmembrane raft

PAG1 EHD2 ERLIN2 KCNA5 KCND2 KCND3 SULF1 TNR NOS3

1.13e-033621489GO:0045121
GeneOntologyCellularComponentcaveola

EHD2 KCNA5 KCND2 KCND3 NOS3

1.17e-031111485GO:0005901
GeneOntologyCellularComponentmembrane microdomain

PAG1 EHD2 ERLIN2 KCNA5 KCND2 KCND3 SULF1 TNR NOS3

1.17e-033641489GO:0098857
GeneOntologyCellularComponentdynactin complex

DCTN2 ACTR10

1.36e-0381482GO:0005869
GeneOntologyCellularComponentcation channel complex

SLCO6A1 KCNA1 KCNA2 KCNA5 KCNA7 KCND2 KCND3

1.45e-032351487GO:0034703
GeneOntologyCellularComponentmonoatomic ion channel complex

GRIN2B SLCO6A1 KCNA1 KCNA2 KCNA5 KCNA7 KCND2 KCND3 SLC26A6

1.52e-033781489GO:0034702
GeneOntologyCellularComponentaxon

ADCY10 NRCAM DCTN2 ACTR10 ALS2 GRIN2B IQGAP1 KCNA1 KCNA2 CLCN3 ARHGEF7 MPP4 STAU2 HSPA8 HTT

1.67e-0389114815GO:0030424
GeneOntologyCellularComponentdendritic spine

SHANK1 ALS2 GRIN2B KCND2 KCND3 CDC42 HSPA8

1.72e-032421487GO:0043197
GeneOntologyCellularComponentneuron spine

SHANK1 ALS2 GRIN2B KCND2 KCND3 CDC42 HSPA8

1.93e-032471487GO:0044309
GeneOntologyCellularComponentglutamatergic synapse

SHANK1 NRCAM ALS2 GRIN2B KCNA1 KCNA2 CLCN3 PLPPR4 KCND2 PIK3C3 CDC42 TNR HSPA8 HTT

2.02e-0381714814GO:0098978
GeneOntologyCellularComponentcell surface

SIGLEC12 ADAM19 NRCAM TCN2 MUC16 GRIN2B ITGA9 KCNA1 CSF1R SIGLEC7 PXDN KCNA5 CLCN3 PLPPR4 SULF1 TNR HSPA8

2.27e-03111114817GO:0009986
GeneOntologyCellularComponentpostsynapse

SHANK1 IQSEC3 NRCAM ALS2 GRIN2B KCNA1 KCNA2 CLCN3 PLPPR4 KCND2 KCND3 PIK3C3 ARHGEF7 CDC42 HSPA8 HTT

2.35e-03101814816GO:0098794
GeneOntologyCellularComponentneuronal cell body

ADCY10 ALS2 GRIN2B CIT KCNA1 KCNA2 CSF1R KCND2 KCND3 ARHGEF7 STAU2 CDC42 HSPA8 HTT

2.47e-0383514814GO:0043025
GeneOntologyCellularComponentphagophore assembly site

BECN2 WDR45 PIK3C3

2.64e-03391483GO:0000407
GeneOntologyCellularComponentcytoplasmic ribonucleoprotein granule

TDRD1 IQGAP1 STAU2 LSM14A PABPC1L CDC42 HTT

3.10e-032691487GO:0036464
GeneOntologyCellularComponentpostsynaptic specialization membrane

NRCAM GRIN2B PLPPR4 KCND2 KCND3 HSPA8

3.12e-032011486GO:0099634
GeneOntologyCellularComponentjuxtaparanode region of axon

KCNA1 KCNA2

3.14e-03121482GO:0044224
GeneOntologyCellularComponentruffle

ALS2 CIT GSN IQGAP1 CLCN3 ARHGEF7

3.52e-032061486GO:0001726
GeneOntologyCellularComponentaxon terminus

GRIN2B KCNA1 KCNA2 CLCN3 MPP4 HSPA8

3.87e-032101486GO:0043679
GeneOntologyCellularComponentplasma membrane raft

EHD2 KCNA5 KCND2 KCND3 NOS3

3.97e-031471485GO:0044853
DomainK_chnl_volt-dep_Kv

KCNA1 KCNA2 KCNA5 KCNA7 KCND2 KCND3

5.54e-08271476IPR003968
DomainBTB_2

KCTD21 KCNA1 KCNA2 KCNA5 KCNA7 KCND2 KCND3

1.85e-07531477PF02214
DomainT1-type_BTB

KCTD21 KCNA1 KCNA2 KCNA5 KCNA7 KCND2 KCND3

1.85e-07531477IPR003131
DomainVG_K_chnl

KCNA1 KCNA2 KCNA5 KCNA7 KCND2 KCND3

1.99e-07331476IPR028325
DomainK_chnl_volt-dep_Kv1

KCNA1 KCNA2 KCNA5 KCNA7

2.52e-0781474IPR003972
DomainChannel_four-helix_dom

SLC9C2 KCNA1 KCNA2 KCNA5 KCNA7 KCND2 KCND3

3.08e-07571477IPR027359
Domain-

SLC9C2 KCNA1 KCNA2 KCNA5 KCNA7 KCND2 KCND3

3.08e-075714771.20.120.350
Domain-

GART CPS1 PCCA

1.29e-041314733.40.50.20
DomainATP_GRASP

GART CPS1 PCCA

1.63e-04141473PS50975
DomainATP-grasp

GART CPS1 PCCA

1.63e-04141473IPR011761
DomainPreATP-grasp_dom

GART CPS1 PCCA

1.63e-04141473IPR016185
Domain-

MSH2 MSH4

1.84e-04314723.30.420.110
DomainShal-type_N

KCND2 KCND3

1.84e-0431472IPR021645
DomainK_chnl_volt-dep_Kv4_C

KCND2 KCND3

1.84e-0431472IPR024587
DomainDUF3399

KCND2 KCND3

1.84e-0431472PF11879
DomainK_chnl_volt-dep_Kv4

KCND2 KCND3

1.84e-0431472IPR003975
DomainShal-type

KCND2 KCND3

1.84e-0431472PF11601
Domain-

GART CPS1 PCCA

2.03e-041514733.30.1490.20
DomainIon_trans_dom

KCNA1 KCNA2 KCNA5 KCNA7 KCND2 KCND3

2.85e-041141476IPR005821
DomainIon_trans

KCNA1 KCNA2 KCNA5 KCNA7 KCND2 KCND3

2.85e-041141476PF00520
DomainATP_grasp_subdomain_1

GART CPS1 PCCA

3.57e-04181473IPR013815
Domain-

GART CPS1 PCCA

3.57e-041814733.30.470.20
DomainDNA_mmatch_repair_MutS_con_dom

MSH2 MSH4

3.65e-0441472IPR007860
DomainMutS_II

MSH2 MSH4

3.65e-0441472PF05188
DomainBTB

KCTD21 KCNA1 KCNA2 KCNA5 KCNA7 KCND2 KCND3

5.64e-041801477SM00225
DomainMUTSd

MSH2 MSH4

6.06e-0451472SM00533
DomainMUTSac

MSH2 MSH4

6.06e-0451472SM00534
DomainMutS_V

MSH2 MSH4

6.06e-0451472PF00488
DomainDNA_mismatch_repair_MutS_clamp

MSH2 MSH4

6.06e-0451472IPR007861
DomainDNA_MISMATCH_REPAIR_2

MSH2 MSH4

6.06e-0451472PS00486
DomainMutS_IV

MSH2 MSH4

6.06e-0451472PF05190
DomainMutS_III

MSH2 MSH4

6.06e-0451472PF05192
DomainDNA_mismatch_repair_MutS_C

MSH2 MSH4

6.06e-0451472IPR000432
DomainCPSASE_1

CPS1 PCCA

6.06e-0451472PS00866
DomainDNA_mismatch_repair_MutS_core

MSH2 MSH4

6.06e-0451472IPR007696
DomainBTB/POZ_dom

KCTD21 KCNA1 KCNA2 KCNA5 KCNA7 KCND2 KCND3

6.63e-041851477IPR000210
DomainSKP1/BTB/POZ

KCTD21 KCNA1 KCNA2 KCNA5 KCNA7 KCND2 KCND3

7.52e-041891477IPR011333
DomainRudment_hybrid_motif

GART PCCA

9.04e-0461472IPR011054
DomainCPSASE_2

CPS1 PCCA

9.04e-0461472PS00867
DomainP-loop_NTPase

RAD51B ADCY10 LONP2 ABCC5 RECQL MSH2 MSH4 ZRANB3 SBNO2 IQGAP1 MYO5C EHD2 RUVBL1 MPP4 CDC42 NLRP13

1.06e-0384814716IPR027417
DomainCbamoylP_synth_lsu-like_ATP-bd

CPS1 PCCA

1.26e-0371472IPR005479
DomainBC-like_N

CPS1 PCCA

1.26e-0371472IPR005481
DomainCPSase_L_D2

CPS1 PCCA

1.26e-0371472PF02786
DomainBiotin_carb_N

CPS1 PCCA

1.26e-0371472PF00289
DomainATP_grasp_subdomain_2

GART CPS1 PCCA

1.83e-03311473IPR013816
PathwayREACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS

KCNA1 KCNA2 KCNA5 KCNA7 KCND2 KCND3

9.69e-07411166MM14546
PathwayREACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS

KCNA1 KCNA2 KCNA5 KCNA7 KCND2 KCND3

1.30e-06431166M1056
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

SHANK1 IQSEC3 NRCAM VPS33A GRIN2B CIT GATAD2B ERLIN2 KCNA1 OXCT1 RUVBL1 PLPPR4 SLC16A1 KCND2 KCND3 ARHGEF7 STAU2 OSBPL8 CDC42 PCCA MAP4K4 HSPA8

4.34e-0911391502236417873
Pubmed

Ion channel expression in the developing enteric nervous system.

KCNA1 KCNA2 KCNA5 CLCN3 KCND2 KCND3

1.21e-0837150625798587
Pubmed

International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels.

KCNA1 KCNA2 KCNA5 KCNA7 KCND2 KCND3

1.98e-0840150616382104
Pubmed

N-terminal PDZ-binding domain in Kv1 potassium channels.

KCNA1 KCNA2 KCNA5 KCND2

2.30e-088150412435606
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

SHANK1 IQSEC3 NRCAM GRIN2B CIT GATAD2B RCOR2 GSN IQGAP1 WDR45 BCL11B KCNA1 KCNA2 PLPPR4 ARHGEF7 CNKSR3 TNR MAP4K4 HSPA8

3.89e-089631501928671696
Pubmed

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.

EPPK1 RTCB DCTN2 HSPH1 GART RECQL AGPS TSFM GSN HP1BP3 IQGAP1 NLN OXCT1 RUVBL1 PTGR1 SLC16A1 STAU2 CDC42 PCCA MTCH2 HSPA8 VAT1

1.09e-0713671502232687490
Pubmed

The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.

EPPK1 RTCB POLR2A HSPH1 GART SRBD1 ZNF446 GATAD2B BCL11B RUVBL1 SLC16A1 NFATC4 LSM14A HSPA8

2.63e-075831501429844126
Pubmed

A Map of Human Mitochondrial Protein Interactions Linked to Neurodegeneration Reveals New Mechanisms of Redox Homeostasis and NF-κB Signaling.

RTCB DCTN2 HSPH1 GART AGPS TSFM GSN HP1BP3 IQGAP1 NLN ERLIN2 RUVBL1 SLC16A1 CDC42 MTCH2 VAT1

3.28e-077861501629128334
Pubmed

Direct binding of CoREST1 to SUMO-2/3 contributes to gene-specific repression by the LSD1/CoREST1/HDAC complex.

TDG MSH2 GATAD2B RCOR2 HP1BP3 RUVBL1 HSPA8

4.11e-07106150719394292
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

EPPK1 RTCB POLR2A HSPH1 VPS33A GART GSN HP1BP3 IQGAP1 ERLIN2 RUVBL1 CDC42 PCCA MTCH2 HSPA8 VAT1

4.65e-078071501630575818
Pubmed

Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.

COX16 AGPS CPS1 TIMMDC1 PARS2 TSFM AGXT2 NLN OXCT1 SLC25A35 SUGCT SLC16A1 AASS ACSF3 SLC25A29 PCCA MTCH2

5.79e-079261501720877624
Pubmed

Host E3 ligase HUWE1 attenuates the proapoptotic activity of the MERS-CoV accessory protein ORF3 by promoting its ubiquitin-dependent degradation.

RTCB DCTN2 POLR2A HSPH1 GART RECQL MSH2 AGPS ANKHD1 GATAD2B TSFM ERLIN2 OXCT1

6.16e-075341501335032548
Pubmed

ARMC5 is part of an RPB1-specific ubiquitin ligase implicated in adrenal hyperplasia.

RTCB DCTN2 POLR2A HSPH1 GART RUVBL1 NFATC4 HSPA8

6.73e-07166150835687106
Pubmed

The homeodomain transcription factor Irx5 establishes the mouse cardiac ventricular repolarization gradient.

KCNA5 KCND2 KCND3

7.81e-075150316239150
Pubmed

Physical mapping of potassium channel gene clusters on mouse chromosomes three and six.

KCNA1 KCNA2 KCNA5

1.56e-06615039286706
Pubmed

Targeted deletion of kcne2 impairs ventricular repolarization via disruption of I(K,slow1) and I(to,f).

KCNA5 KCND2 KCND3

1.56e-066150318603586
Pubmed

Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context.

ADCY10 COX16 CPS1 TIMMDC1 PARS2 TSFM AGXT2 NLN OTC OXCT1 SLC25A35 SUGCT AASS SLC9B2 ACSF3 SLC25A29 PCCA MTCH2

2.15e-0611361501834800366
Pubmed

KAP1 facilitates reinstatement of heterochromatin after DNA replication.

EPPK1 RTCB POLR2A RECQL MSH2 AGPS CPS1 ANKHD1 IQGAP1 OXCT1 RUVBL1 STAU2 FHL3 CDC42

2.43e-067041501429955894
Pubmed

SARS-CoV-2 uses Spike glycoprotein to control the host's anaerobic metabolism by inhibiting LDHB.

EPPK1 RTCB GART RECQL AGPS GSN IQGAP1 SLC16A1 AASS OSBPL8 CDC42 MTCH2 VAT1

2.54e-066071501339147351
Pubmed

Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.

KCNA1 KCNA2 KCNA5 CLCN3 KCNA7 KCND2 KCND3

2.56e-06139150716985003
Pubmed

Heteromultimeric delayed-rectifier K+ channels in schwann cells: developmental expression and role in cell proliferation.

KCNA1 KCNA2 KCNA5

2.72e-06715039852577
Pubmed

Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.

IQSEC3 NRCAM HSPH1 GRIN2B CIT KCNA2 SLC16A1 KCND2 ARHGEF7 HTT

2.92e-063471501017114649
Pubmed

A mitochondrial protein compendium elucidates complex I disease biology.

COX16 AGPS TIMMDC1 PARS2 TSFM AGXT2 NLN OTC OXCT1 SLC25A35 SUGCT SLC16A1 AASS ACSF3 SLC25A29 PCCA MTCH2

3.05e-0610471501718614015
Pubmed

Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.

EPPK1 RTCB LONP2 POLR2A HSPH1 GART RECQL TFIP11 MSH2 CPS1 ANKHD1 GSN HP1BP3 IQGAP1 RUVBL1 SLC16A1 ARHGEF7 OSBPL8 MTCH2 HSPA8

3.19e-0614151502028515276
Pubmed

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.

SHANK1 IQSEC3 NRCAM GRIN2B CIT GSN IQGAP1 CDC42 TNR

3.97e-06281150928706196
Pubmed

The European renal genome project: an integrated approach towards understanding the genetics of kidney development and disease.

GART SLC5A9 SLCO1B3 CPS1 SLCO6A1 AQP6 SLC2A2 TFE3

4.19e-06212150819521566
Pubmed

Chromosomal mapping in the mouse of eight K(+)-channel genes representing the four Shaker-like subfamilies Shaker, Shab, Shaw, and Shal.

KCNA1 KCNA2 KCNA5 KCND2

4.62e-062615047905852
Pubmed

Genomic organization, chromosomal localization, tissue distribution, and biophysical characterization of a novel mammalian Shaker-related voltage-gated potassium channel, Kv1.7.

KCNA1 KCNA2 KCNA7

6.48e-06915039488722
Pubmed

Deubiquitinating enzyme PSMD14 promotes tumor metastasis through stabilizing SNAIL in human esophageal squamous cell carcinoma.

RTCB LONP2 HSPH1 GART MSH2 ERLIN2 RUVBL1 SLC16A1 LSM14A HSPA8

6.96e-063831501029331416
Pubmed

The insulin receptor substrate of 53 kDa (IRSp53) limits hippocampal synaptic plasticity.

SHANK1 GRIN2B ARHGEF7 CDC42

7.26e-0629150419208628
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

EPPK1 RTCB HSPH1 GART RECQL MSH2 SRBD1 CIT GSN HP1BP3 IQGAP1 RUVBL1 SLC16A1 STAU2 LSM14A C9 CDC42 HSPA8

8.65e-0612571501836526897
Pubmed

Developmental expression of voltage-sensitive K+ channels in mouse skeletal muscle and C2C12 cells.

KCNA1 KCNA2 KCNA5

9.23e-061015031383027
Pubmed

The Catalytically Inactive Mutation of the Ubiquitin-Conjugating Enzyme CDC34 Affects its Stability and Cell Proliferation.

POLR2A RECQL AGPS SRBD1 TSFM SLC16A1 ACSF3 HSPA8

9.46e-06237150829564676
Pubmed

Voltage-gated potassium channel genes are clustered in paralogous regions of the mouse genome.

KCNA1 KCNA2 KCNA5 KCNA7

9.55e-063115048034307
Pubmed

Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.

EPPK1 LONP2 GART ALS2 GSN HP1BP3 ARHGAP6 RUVBL1 SLC16A1 ARHGEF10 ARHGEF7 CNKSR3 LSM14A CDC42 MTCH2

1.09e-059161501532203420
Pubmed

Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.

COL12A1 EPPK1 RTCB HSPH1 VPS33A GART RECQL AGPS ANKHD1 TSFM ERLIN2 PXDN PIK3C3 OSBPL8 CDC42 POFUT2 MTCH2 HSPA8

1.32e-0512971501833545068
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

SHANK1 IQSEC3 NRCAM RTCB DCTN2 HSPH1 GRIN2B CIT GSN HP1BP3 IQGAP1 ERLIN2 KCNA1 PLPPR4 KCND3 OSBPL8 TNR MTCH2 HSPA8

1.38e-0514311501937142655
Pubmed

Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome.

SHANK1 IQSEC3 GRIN2B CIT GSN KCNA1 KCNA2 ARHGEF7

1.43e-05251150827507650
Pubmed

Multi-omics profiling identifies a deregulated FUS-MAP1B axis in ALS/FTD-associated UBQLN2 mutants.

EPPK1 HSPH1 CPS1 IQGAP1 RUVBL1 SLC16A1 STAU2 HSPA8

1.65e-05256150835777956
Pubmed

ER-export and ARFRP1/AP-1-dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication.

MBTPS1 PAG1 GRK6 ABCC5 MSH2 AGPS TIMMDC1 TSFM ERLIN2 SLC16A1 TMEM87B OSBPL8 PCCA MAP4K4 SLC26A6

1.71e-059521501538569033
Pubmed

Stimulatory roles of nitric-oxide synthase 3 and guanylyl cyclase in platelet activation.

ADCY10 NOS3

1.85e-052150216144836
Pubmed

Multiple mRNA isoforms encoding the mouse cardiac Kv1-5 delayed rectifier K+ channel.

KCNA1 KCNA5

1.85e-05215028226976
Pubmed

Msh2 acts in medium-spiny striatal neurons as an enhancer of CAG instability and mutant huntingtin phenotypes in Huntington's disease knock-in mice.

MSH2 HTT

1.85e-052150222970194
Pubmed

De novo KCNA1 variants in the PVP motif cause infantile epileptic encephalopathy and cognitive impairment similar to recurrent KCNA2 variants.

KCNA1 KCNA2

1.85e-052150230055040
Pubmed

INTRACELLULAR TRANSPORT. PI4P/phosphatidylserine countertransport at ORP5- and ORP8-mediated ER-plasma membrane contacts.

OSBPL5 OSBPL8

1.85e-052150226206935
Pubmed

Estrogen contributes to gender differences in mouse ventricular repolarization.

KCNA5 KCND3

1.85e-052150219608983
Pubmed

Enhanced striatal NR2B-containing N-methyl-D-aspartate receptor-mediated synaptic currents in a mouse model of Huntington disease.

GRIN2B HTT

1.85e-052150215240759
Pubmed

Sema4D deficiency enhances glucose tolerance through GLUT2 retention in hepatocytes.

SEMA4D SLC2A2

1.85e-052150239334386
Pubmed

Oxysterol-binding protein related-proteins (ORPs) 5 and 8 regulate calcium signaling at specific cell compartments.

OSBPL5 OSBPL8

1.85e-052150229748134
Pubmed

Molecular cloning, characterization, and genomic localization of a human potassium channel gene.

KCNA1 KCNA5

1.85e-05215021349297
Pubmed

The Application of Next-Generation Sequencing (NGS) in Neonatal-Onset Urea Cycle Disorders (UCDs): Clinical Course, Metabolomic Profiling, and Genetic Findings in Nine Chinese Hyperammonemia Patients.

CPS1 OTC

1.85e-052150232934962
Pubmed

ORP5/ORP8 localize to endoplasmic reticulum-mitochondria contacts and are involved in mitochondrial function.

OSBPL5 OSBPL8

1.85e-052150227113756
Pubmed

Mutations in the genes KCND2 and KCND3 encoding the ion channels Kv4.2 and Kv4.3, conducting the cardiac fast transient outward current (ITO,f), are not a frequent cause of long QT syndrome.

KCND2 KCND3

1.85e-052150215563876
Pubmed

Kv4.3-Encoded Fast Transient Outward Current Is Presented in Kv4.2 Knockout Mouse Cardiomyocytes.

KCND2 KCND3

1.85e-052150226196737
Pubmed

Genomic organisation and chromosomal localisation of two members of the KCND ion channel family, KCND2 and KCND3.

KCND2 KCND3

1.85e-052150210942109
Pubmed

Msh2 deficiency prevents in vivo somatic instability of the CAG repeat in Huntington disease transgenic mice.

MSH2 HTT

1.85e-052150210581038
Pubmed

Voltage-gated delayed rectifier K v 1-subunits may serve as distinctive markers for enteroglial cells with different phenotypes in the murine ileum.

KCNA1 KCNA2

1.85e-052150219549557
Pubmed

Dendritic Kv4.2 potassium channels selectively mediate spatial pattern separation in the dentate gyrus.

KCND2 KCND3

1.85e-052150234386734
Pubmed

Cdc42 protein acts upstream of IQGAP1 and regulates cytokinesis in mouse oocytes and embryos.

IQGAP1 CDC42

1.85e-052150218662680
Pubmed

Moving gating charges through the gating pore in a Kv channel voltage sensor.

KCNA1 KCNA2

1.85e-052150224782544
Pubmed

Activated Cdc42-bound IQGAP1 determines the cellular endocytic site.

IQGAP1 CDC42

1.85e-052150224100016
Pubmed

Kv1.1 and Kv1.2: similar channels, different seizure models.

KCNA1 KCNA2

1.85e-052150222612818
Pubmed

Association of the Kv1 family of K+ channels and their functional blueprint in the properties of auditory neurons as revealed by genetic and functional analyses.

KCNA1 KCNA2

1.85e-052150223864368
Pubmed

Association of HSP105 with HSC70 in high molecular mass complexes in mouse FM3A cells.

HSPH1 HSPA8

1.85e-05215029675148
Pubmed

A dual role for IQGAP1 in regulating exocytosis.

IQGAP1 CDC42

1.85e-052150218216334
Pubmed

Inter-Regulation of Kv4.3 and Voltage-Gated Sodium Channels Underlies Predisposition to Cardiac and Neuronal Channelopathies.

KCNA5 KCND3

1.85e-052150232709127
Pubmed

Phosphorylation of IQGAP1 modulates its binding to Cdc42, revealing a new type of rho-GTPase regulator.

IQGAP1 CDC42

1.85e-052150215355962
Pubmed

Voltage-gated K+ channels in rat small cerebral arteries: molecular identity of the functional channels.

KCNA2 KCNA5

1.85e-052150212815189
Pubmed

Isolation and characterization of the human gene encoding Ito: further diversity by alternative mRNA splicing.

KCND2 KCND3

1.85e-05215029843794
Pubmed

IQGAP1 promotes cell motility and invasion.

IQGAP1 CDC42

1.85e-052150212900413
Pubmed

In vivo evidence for NMDA receptor-mediated excitotoxicity in a murine genetic model of Huntington disease.

GRIN2B HTT

1.85e-052150219279257
Pubmed

Hsp105alpha suppresses Hsc70 chaperone activity by inhibiting Hsc70 ATPase activity.

HSPH1 HSPA8

1.85e-052150215292236
Pubmed

Calmodulin modulates the interaction between IQGAP1 and Cdc42. Identification of IQGAP1 by nanoelectrospray tandem mass spectrometry.

IQGAP1 CDC42

1.85e-05215029182573
Pubmed

Localization of Kv1.1 and Kv1.2, two K channel proteins, to synaptic terminals, somata, and dendrites in the mouse brain.

KCNA1 KCNA2

1.85e-05215028046438
Pubmed

Sound Localization in Preweanling Mice Was More Severely Affected by Deleting the Kcna1 Gene Compared to Deleting Kcna2, and a Curious Inverted-U Course of Development That Appeared to Exceed Adult Performance Was Observed in All Groups.

KCNA1 KCNA2

1.85e-052150231410614
Pubmed

IQGAP1 is a component of Cdc42 signaling to the cytoskeleton.

IQGAP1 CDC42

1.85e-052150211948177
Pubmed

Differential expression of I(A) channel subunits Kv4.2 and Kv4.3 in mouse visual cortical neurons and synapses.

KCND2 KCND3

1.85e-052150217122053
Pubmed

Critical role of vascular peroxidase 1 in regulating endothelial nitric oxide synthase.

PXDN NOS3

1.85e-052150228264790
Pubmed

Mismatch repair gene Msh2 modifies the timing of early disease in Hdh(Q111) striatum.

MSH2 HTT

1.85e-052150212554681
Pubmed

Functional roles for the striatal-enriched transcription factor, Bcl11b, in the control of striatal gene expression and transcriptional dysregulation in Huntington's disease.

BCL11B HTT

1.85e-052150218595722
Pubmed

ORP5 and ORP8 bind phosphatidylinositol-4, 5-biphosphate (PtdIns(4,5)P 2) and regulate its level at the plasma membrane.

OSBPL5 OSBPL8

1.85e-052150228970484
Pubmed

Expression and localization of Kv1 potassium channels in rat dorsal and ventral spinal roots.

KCNA1 KCNA2

1.85e-052150218053989
Pubmed

Gradual decorrelation of CA3 ensembles associated with contextual discrimination learning is impaired by Kv1.2 insufficiency.

KCNA1 KCNA2

1.85e-052150234964210
Pubmed

Identification and characterization of the Cdc42-binding site of IQGAP1.

IQGAP1 CDC42

1.85e-052150212745076
Pubmed

Polymorphisms of ABCC5 and NOS3 genes influence doxorubicin cardiotoxicity in survivors of childhood acute lymphoblastic leukemia.

ABCC5 NOS3

1.85e-052150226345518
Pubmed

Elevated IQGAP1 and CDC42 levels correlate with tumor malignancy of human glioma.

IQGAP1 CDC42

1.85e-052150228035419
Pubmed

O-GlcNAcylation enhances CPS1 catalytic efficiency for ammonia and promotes ureagenesis.

CPS1 PCCA

1.85e-052150236064721
Pubmed

Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.

ADCY10 RTCB DCTN2 POLR2A HSPH1 VPS33A GART MSH2 ANKHD1 GATAD2B PARS2 HP1BP3 IQGAP1 RUVBL1 SLC16A1 LSM14A CDC42 HSPA8

1.93e-0513351501829229926
Pubmed

Differential impacts of Cntnap2 heterozygosity and Cntnap2 null homozygosity on axon and myelinated fiber development in mouse.

NRCAM BCL11B KCNA2

2.18e-0513150336793543
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

RTCB CEP85L ALS2 MAP3K6 KCNA7 SLC16A1 ARHGEF10 PIK3C3 AASS CNKSR3 ANKRD11 OSBPL8 CDC25C MAP4K4

2.34e-058611501436931259
Pubmed

Insights into the ubiquitin-proteasome system of human embryonic stem cells.

RTCB DCTN2 ACTR10 GART TFIP11 ERLIN2 SLC16A1 ANKRD11

2.35e-05269150829511261
Pubmed

Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome.

SHANK1 GRIN2B CIT KCNA1 KCNA2 PLPPR4 CSNK1G1

2.50e-05197150736604605
Pubmed

Functional suppression of Kcnq1 leads to early sodium channel remodelling and cardiac conduction system dysmorphogenesis.

KCNA5 KCND2 KCND3

2.76e-0514150323542581
Pubmed

N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.

RTCB GART ANKHD1 GSN IQGAP1 EHD2 LSM14A HSPA8 VAT1

2.85e-05360150933111431
Pubmed

ADAM10 hyperactivation acts on piccolo to deplete synaptic vesicle stores in Huntington's disease.

IQSEC3 NRCAM DCTN2 CIT ERLIN2 PCCA HTT

2.93e-05202150733601422
Pubmed

Transcriptome analysis of mouse stem cells and early embryos.

FOXN2 COL12A1 DCAF4L2 ALS2 ITGA9 GSN HP1BP3 STAU2 SLC26A6

3.04e-05363150914691545
Pubmed

ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.

RTCB GART RECQL MSH2 CIT GSN HP1BP3 IQGAP1 ERLIN2 RUVBL1 CSNK1G1 CDC42

3.15e-056601501232780723
Pubmed

Neuronal interleukin-16 (NIL-16): a dual function PDZ domain protein.

GRIN2B KCND2 KCND3

3.44e-0515150310479680
Pubmed

The gluconeogenic enzyme PCK1 phosphorylates INSIG1/2 for lipogenesis.

ERLIN2 PXDN RUVBL1 LSM14A MTCH2 HSPA8

3.53e-05141150632322062
Pubmed

Interrogating the protein interactomes of RAS isoforms identifies PIP5K1A as a KRAS-specific vulnerability.

SEMA4D PAG1 GRK6 VPS33A ABCC5 SLC16A1 OSBPL8 CDC42 MAP4K4 VAT1

3.80e-054671501030194290
InteractionKCNA5 interactions

RHBDD1 DCTN2 KCNA2 KCNA5 KCND3 HSPA8

4.73e-06601466int:KCNA5
InteractionDLG4 interactions

SHANK1 NRCAM ALS2 GRIN2B CIT KCNA1 KCNA2 KCNA5 RUVBL1 PLPPR4 KCND2 CSNK1G1 CNKSR3 HTT

5.03e-0644914614int:DLG4
InteractionDLGAP1 interactions

SHANK1 IQSEC3 GRIN2B CIT GSN KCNA1 KCNA2 CNKSR3 MAP4K4

6.70e-061801469int:DLGAP1
InteractionLAMTOR1 interactions

RTCB VPS33A ABCC5 TFE3 IQGAP1 RUVBL1 SLC16A1 ARHGEF10 PIK3C3 OSBPL8 DTX2 CDC42 MAP4K4 MTCH2 HSPA8 HTT VAT1

1.95e-0572214617int:LAMTOR1
InteractionTNIK interactions

SHANK1 IQSEC3 DCTN2 GRIN2B CIT GATAD2B RCOR2 GSN BCL11B TNR MAP4K4 HTT

2.22e-0538114612int:TNIK
InteractionKCND3 interactions

KCNA2 KCNA5 RUVBL1 KCND3 HSPA8

2.75e-05491465int:KCND3
InteractionKCNAB1 interactions

KCNA1 KCNA2 KCNA5 HTT

2.97e-05251464int:KCNAB1
InteractionSH2D3C interactions

POLR2A GART SRBD1 TIMMDC1 PARS2 GSN EHD2 OSBPL8

3.71e-051721468int:SH2D3C
InteractionNDUFS3 interactions

RECQL AGPS TIMMDC1 CIT TSFM OTC OXCT1 SLC16A1 ASXL3 CDC42 MTCH2 HTT

4.33e-0540814612int:NDUFS3
InteractionYWHAH interactions

EPPK1 RTCB CEP85L HSPH1 ALS2 MAP3K6 TFE3 IQGAP1 SLC16A1 PIK3C3 ARHGEF7 AASS CNKSR3 OSBPL5 ANKRD11 OSBPL8 CDC25C CDC42 MAP4K4 HTT UBFD1

4.60e-05110214621int:YWHAH
InteractionNEXN interactions

ACTR10 CIT GSN IQGAP1 MYO5C HSPA8

5.24e-05911466int:NEXN
InteractionYARS2 interactions

CPS1 CIT PARS2 TSFM OXCT1 ACSF3 CDC42 PCCA HSPA8

5.53e-052351469int:YARS2
Cytoband12p12

SLCO1B3 RECQL GRIN2B

9.74e-0613151312p12
Cytoband19q13.3

SHANK1 EHD2 SIGLEC7 KCNA7

1.61e-0482151419q13.3
Cytoband17p13.1

POLR2A SAT2 SLC25A35 CFAP52

6.45e-04118151417p13.1
GeneFamilyPotassium voltage-gated channels

KCNA1 KCNA2 KCNA5 KCNA7 KCND2 KCND3

1.15e-07401066274
GeneFamilySolute carriers

SLC6A16 SLC5A9 SLCO1B3 SLCO6A1 SLC9C2 SLC2A2 SLC25A35 SLC16A1 SLC9B2 SLC25A29 MTCH2 SLC29A4 SLC26A6

5.38e-0739510613752
GeneFamilyMutS homologs|PWWP domain containing

MSH2 MSH4

3.37e-04510621026
GeneFamilyOxysterol binding proteins|Pleckstrin homology domain containing

OSBPL5 OSBPL8

2.16e-03121062670
CoexpressionPARENT_MTOR_SIGNALING_DN

ADAM19 NRCAM AQP6 SIGLEC7 FHL3

5.04e-06441495M16644
CoexpressionXU_GH1_AUTOCRINE_TARGETS_DN

COL12A1 NRCAM HSPH1 CIT NLN PXDN SULF1

1.03e-051311497M16384
CoexpressionGSE12392_WT_VS_IFNB_KO_CD8A_NEG_SPLEEN_DC_UP

ADAM19 RTCB ALS2 OXCT1 RUVBL1 SLC16A1 TXNDC16 SLC26A6

1.98e-052001498M7148
CoexpressionHE_LIM_SUN_FETAL_LUNG_C0_MYOFIBROBLAST_2_CELL

PAG1 COL12A1 NRCAM ITGA9 ARHGAP6 PLPPR4

2.93e-051041496M45682
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PAG1 COL12A1 LRRN1 NRCAM FAT3 ITGA9 ARHGAP6 PLPPR4

3.13e-07192151872881b280a415e65f87a80ca1369cbb0b722a0c4
ToppCellwk_15-18-Mesenchymal-Myofibro_&_SMC-Myofibro_2|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

PAG1 FAT3 ITGA9 ARHGAP6 CLCN3 PLPPR4 TNR

1.12e-061571517b9d04ee417c0d8ea0801d10f1c54e138587009fd
ToppCellCV-Severe-7|Severe / Virus stimulation, Condition and Cluster

MBTPS1 PAG1 ADAM19 ZRANB3 ARHGEF7 TXNDC16 HTT

2.48e-06177151782fdd6185b368f54f03de389427cbe3071d21a99
ToppCellLA|World / Chamber and Cluster_Paper

COL12A1 ADAM19 GSN ARHGAP6 PXDN KCND2 SULF1

4.39e-061931517d4bf89437216baf489ea0239136dcedf3b6714af
ToppCellFibroblasts-DKK3+_Fibroblasts|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

COL12A1 ADAMTS2 EHD2 KCNA1 PXDN ARHGEF10 SULF1

5.19e-0619815174f4632f26a2043c5e4ab89031b4229b5dca1bd48
ToppCellfacs-Brain_Non-Myeloid-Hippocampus|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA4D LRRN1 GSN CLCN3 ANKRD11 TXNDC16 MAP4K4

5.55e-062001517fc28f71ca1cd0fdae66009ae5afe175d22f2bd8c
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL12A1 FAT3 GRIN2B CPS1 SULF1 AASS

1.79e-051601516c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL12A1 FAT3 GRIN2B CPS1 SULF1 AASS

1.79e-05160151625c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell367C-Lymphocytic-NK_cells-NK_cell_B2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

MYO5C SIGLEC7 PXDN ARHGEF10 POFUT2 UBFD1

1.99e-0516315166c4d4c55fc8a731acca13c1ba7287f238a9d81e0
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_naive-D|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SIGLEC12 PAG1 TCN2 ADAMTS2 SLC5A9 EHD2

1.99e-0516315164be3158f2a0ab460cfea8080a7370922910b5da9
ToppCelltumor_Lymph_Node_/_Brain-T/NK_cells-CD8+/CD4+_Mixed_Th|T/NK_cells / Location, Cell class and cell subclass

TCN2 ZNF446 PARS2 PIK3C3 OSBPL8 NOS3

2.78e-05173151642c911ed16fabdabef063830e8407192d8bde950
ToppCellfacs-Brain_Myeloid-Cerebellum-3m-Myeloid-nan|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT3 ABCC5 GSN CSF1R FHL3 MAP4K4

2.78e-051731516869da6a65d1b9b7529c666ec44e3c8ddec2ea408
ToppCellfacs-Brain_Myeloid-Cerebellum-3m-Myeloid|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT3 ABCC5 GSN CSF1R FHL3 MAP4K4

2.78e-0517315160672bd8a4a9d18af343d01f09253fb3388896c10
ToppCellfacs-Brain_Myeloid-Cerebellum-3m|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT3 ABCC5 GSN CSF1R FHL3 MAP4K4

2.78e-051731516870e091ec30be01a900e1cb8b9ef1880e3b7b50d
ToppCellfacs-Brain_Myeloid-Cerebellum-3m-Myeloid-microglial_cell|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT3 ABCC5 GSN CSF1R FHL3 MAP4K4

2.97e-0517515161ea6cf9da26601646f57fa14d558a5e9e1f0b345
ToppCellCV-Severe-7|CV / Virus stimulation, Condition and Cluster

MBTPS1 PAG1 ADAM19 ZRANB3 TXNDC16 HTT

3.06e-0517615163de0c7d77210049e5616db21eed1490a17a5ec2d
ToppCelldroplet-Fat-SCAT-30m-Mesenchymal-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL12A1 NRCAM SLC5A9 GSN KCNA1 KCNA2

3.26e-0517815165cf12927f0756c4d8a289fe4308d736382e6212e
ToppCell5'-Adult-LymphNode-Endothelial-blood_vessel_EC-arterial_capillary|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TCN2 MUC16 MAP3K6 ADGRL4 EHD2 VAT1

3.26e-051781516360d7a987f91d6d721487a921824057ec31a7332
ToppCelldroplet-Kidney-nan-3m-Mesenchymal-podocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL12A1 COL20A1 TDG KCNA1 KCND2 SULF1

3.58e-0518115160b1e7335648823b1d83bdfa878ccd44efe7bba9a
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

PAG1 ADAM19 ITGA9 ARHGAP6 PLPPR4 FHL3

3.81e-051831516e84539978ab4de42e19186aed00f24bb50cbc21f
ToppCellwk_20-22-Mesenchymal-Myofibro_&_SMC-Myofibro_3|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

NRCAM FAT3 MEPE ARHGAP6 CLCN3 PLPPR4

3.81e-051831516f4ea7113ce9099222743d9ff02388d3d8a9e987b
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL12A1 NRCAM FAT3 GRIN2B CPS1 ASXL3

3.93e-0518415162cbed6462fea2622871bb7e49b0df3d984239281
ToppCell3'-Adult-SmallIntestine-Epithelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC5A9 CPS1 SLC2A2 AGXT2 OTC PTGR1

3.93e-051841516ed7a8e79e5723a5f5a03f542203d9e50bdef5f50
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL12A1 NRCAM FAT3 GRIN2B CPS1 ASXL3

3.93e-051841516ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL12A1 NRCAM FAT3 GRIN2B CPS1 ASXL3

3.93e-0518415162b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell3'-Adult-SmallIntestine-Epithelial-mature_enterocytic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC5A9 CPS1 SLC2A2 AGXT2 OTC PTGR1

4.17e-051861516bdd9d3a432aab46e733469b362f0064d35c1ac49
ToppCell3'-Adult-SmallIntestine-Epithelial-mature_enterocytic-Enterocyte|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC5A9 CPS1 SLC2A2 AGXT2 OTC PTGR1

4.30e-0518715169042bd0f57213a51503d9df2e4dce3209b7772d3
ToppCellLA-01._Fibroblast_I|World / Chamber and Cluster_Paper

COL12A1 SLC5A9 GSN PXDN KCND2 SULF1

4.30e-0518715164ea486991f66c29728d127171a07b81404ec0b78
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

PAG1 ADAM19 NRCAM ITGA9 PLPPR4 FHL3

4.30e-051871516387cb27c8a20031cd87381a9e1172f1f62e1488b
ToppCellControl-Fibroblasts-Other_FB|Control / group, cell type (main and fine annotations)

NRCAM ADAMTS2 FAT3 ARHGAP6 PLPPR4 SUGCT

4.30e-051871516bd3739c4a52aa1ba5deffd778e113a9800f7e158
ToppCelldroplet-Heart-nan-18m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL12A1 NRCAM RCOR2 KCNA1 KCNA2 KCND3

4.56e-0518915160493f7b79127c207fd7ade778ef4810500495d7e
ToppCellpdx-Tumor_cells-T8|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

CPS1 SLC2A2 GSN AGXT2 PTGR1 SUGCT

4.70e-051901516b05db0de9b6ae01dd30074453f7de44f7397631e
ToppCell3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CEP85L CPS1 ADGRL4 EXD3 ARHGEF10 NOS3

4.70e-051901516d0297d678498e346e56cf95fe9e3db7d3ad3b837
ToppCellfacs-Heart-LA-3m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRN1 ADGRL4 EHD2 SCARF1 KCNA5 NOS3

4.84e-051911516a15f0fb4bd7dd77ef5f931b6fc9d68697deec1d1
ToppCellfacs-Heart-LA-3m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRN1 ADGRL4 EHD2 SCARF1 KCNA5 NOS3

4.84e-051911516827be47d3574c6c5b021c6f1c1670834344f10cb
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-3|TCGA-Ovary / Sample_Type by Project: Shred V9

ADAM19 ADAMTS2 SBNO2 EHD2 KCND2 SULF1

4.84e-05191151680d30d8eedb4c70b58440646325bc04c5700803e
ToppCellfacs-BAT-Fat-18m-Endothelial|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRL4 EHD2 SCARF1 PXDN KCNA5 NOS3

4.98e-0519215163a99c521c599a289ee2309d97be5ceb99f8aa220
ToppCellfacs-BAT-Fat-18m-Endothelial-endothelial_cell|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRL4 EHD2 SCARF1 PXDN KCNA5 NOS3

4.98e-051921516f9777e0fdd86c2a514f05a42502888329a94b396
ToppCellfacs-BAT-Fat-18m-Endothelial-nan|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRL4 EHD2 SCARF1 PXDN KCNA5 NOS3

4.98e-051921516562e15876088af9189744c9b2de5c4863d7f15fd
ToppCellwk_20-22-Mesenchymal-Myofibro_&_SMC-Myofibro_2|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

COL12A1 NRCAM ITGA9 ARHGAP6 CLCN3 PLPPR4

5.12e-0519315162f203f6f0c2135acb046c9351a633c3b5b254a46
ToppCellPCW_13-14-Endothelial-Endothelial_mature-endo_venous_(13)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

TCN2 GRIN2B ADGRL4 SCARF1 OTC VAT1

5.12e-05193151684d1c1b7d3a1cb80f175527e3c89a2c3da7657f7
ToppCellfacs-Thymus-nan-3m|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA4D MBTPS1 ABCC5 BCL11B SLC16A1 MAP4K4

5.27e-051941516f1661f9f2439fca5c1012c693b0744c4e3b90a9b
ToppCellfacs-Thymus-nan|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA4D MBTPS1 ABCC5 BCL11B SLC16A1 MAP4K4

5.27e-051941516cda1b197efb199330ea7ab25a7cee22cae22589d
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM1_(8)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

PAG1 FAT3 MEPE ARHGAP6 CLCN3 PLPPR4

5.27e-051941516fb80a0271ccb1cb3f954ebcf2c5945cb6adb6b8c
ToppCellfacs-Thymus-nan-3m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA4D MBTPS1 ABCC5 BCL11B SLC16A1 MAP4K4

5.27e-05194151666c056232ac216780acf4cc8ea325bd8ed1909c9
ToppCellTCGA-Blood_and_Bone_Marrow-Primary_Tumor-Diffuse_large_B-cell_lymphoma-DLBCL-1|TCGA-Blood_and_Bone_Marrow / Sample_Type by Project: Shred V9

COL12A1 ADAM19 ADGRL4 PLPPR4 SULF1 NOS3

5.27e-051941516eaeeb84576270cc3fc59002ba33bff9639bb0b02
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_neuro-secretory|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TCN2 FAT3 MUC16 MSH4 ASXL3 SLC29A4

5.27e-0519415162dcc3b99dbedaf8a6916891c85091ddb79d7ee31
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_myocytic|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

PAG1 COL12A1 ADAM19 NRCAM ARHGAP6 PLPPR4

5.27e-05194151667f5e2f05a8de2213ab80d5ea16fdee121684633
ToppCell3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_aerocyte_capillary-EC_aerocyte_capillary_L.2.0.1.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADGRL4 SCARF1 KCND2 ARHGEF10 TNR VAT1

5.43e-051951516e8992c549dad9a88d2b8d01039a8d02a950b29b4
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Newborn-41|World / Primary Cells by Cluster

SEMA4D PAG1 GRIN2B KCND2 MAP4K4 HSPA8

5.58e-051961516dee0984cd63a1a2fdebb4421af48ab566a5b684e
ToppCellNS-critical-LOC-Myeloid-Macrophage|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

TCN2 ADAMTS2 AGPS CSF1R SIGLEC7 VAT1

5.74e-0519715165fb0696376a5501b7c87e0f2f5e4fff3da2903f2
ToppCell5'-Adult-SmallIntestine-Epithelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC5A9 CPS1 SAT2 SLC2A2 OTC PTGR1

5.91e-0519815168d629492d2199de8e036c19e9dacceb9c9e721a0
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL12A1 ADAMTS2 ITGA9 PXDN SULF1 TNR

5.91e-05198151609be07ebfc3e49c3858e9b74605b69cf4fc28b56
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_neuro-secretory-Ionocyte_n_Brush|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

NRCAM TCN2 FAT3 MUC16 MSH4 ASXL3

5.91e-051981516dd0465b45b02cb8edf0914d19afb52fcaaeb012c
ToppCellbackground-Hepatic_Stellate_cells|background / Sample and Cell Type and Tumor Cluster (all cells)

PAG1 COL12A1 ADAMTS2 FAT3 ITGA9 ARHGAP6

5.91e-051981516bd11b0e9e80449aab979a02c1023e0638c431c7c
ToppCell5'-Adult-SmallIntestine-Epithelial-mature_enterocytic-Enterocyte|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC5A9 CPS1 SAT2 SLC2A2 OTC PTGR1

5.91e-0519815166e6af8fad09f8e48b3f2ce463d5773b6a69864d1
ToppCell3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TCN2 GSN ADGRL4 SCARF1 OTC NOS3

5.91e-05198151671ee440b1ac566db63d0b415c50a0ad064d14f15
ToppCellControl-Control-Lymphocyte-T/NK-CD4+_T_activated|Control / Disease, condition lineage and cell class

NPR2 EPPK1 NRCAM BCL11B PABPC1L SLC29A4

5.91e-051981516ee71543559836fd59adc0da877b2ca538cba60cb
ToppCell5'-Adult-SmallIntestine|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC5A9 CPS1 SAT2 SLC2A2 OTC PTGR1

6.07e-051991516a5fffe381be1ba7d192b68d1d3937ce47663658e
ToppCellTracheal-10x3prime_v2-Stromal-Fibroblastic-Fibro_peribronchial|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

PAG1 NPR2 KCNA7 PLPPR4 SUGCT NFATC4

6.07e-051991516e9009eee7f77b9c9917f8e0e723001d9e76eb553
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Macroglial-oligodendrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA4D LRRN1 GSN KCNA1 ARHGEF10 TXNDC16

6.07e-05199151667d8c7e5356f5d409d4f98e8338cf6c499fd7aee
ToppCell5'-Adult-SmallIntestine-Epithelial-mature_enterocytic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC5A9 CPS1 SAT2 SLC2A2 OTC PTGR1

6.07e-05199151601c2721bc82cd672e9477029b4a7ecc77e2f1b00
ToppCell11.5-Airway-Mesenchymal-Airway_Smooth_Muscle|Airway / Age, Tissue, Lineage and Cell class

PAG1 ADAM19 ITGA9 ARHGAP6 PLPPR4 FHL3

6.07e-0519915161a8c77d241bd817a195e1532fd25f51358cb1ff1
ToppCellCOVID-19-kidney-Fibroblast-1|kidney / Disease (COVID-19 only), tissue and cell type

PAG1 COL12A1 ADAMTS2 PXDN NFATC4 SULF1

6.07e-0519915169503646ff1ad248181146ce767e9d12e882ec3bd
ToppCelltumor_Lymph_Node_/_Brain-Fibroblasts-Myofibroblasts|Fibroblasts / Location, Cell class and cell subclass

PAG1 COL12A1 ADAMTS2 SULF1 CDC42 HSPA8

6.24e-052001516eabb7d4aa92ace7d970bcd3fae2c7cb5400a43b4
ToppCellMacroglial-Polydendrocytes-PDGFRA-|Macroglial / cells hierarchy compared to all cells using T-Statistic

COL20A1 GRIN2B PXDN PLPPR4 KCND2 TNR

6.24e-052001516f17b5a54e8f9eba9dcd0808ba4e8d275ac41bce2
ToppCellMacroglial-Polydendrocytes-PDGFRA--|Macroglial / cells hierarchy compared to all cells using T-Statistic

COL20A1 GRIN2B PXDN PLPPR4 KCND2 TNR

6.24e-052001516cc3409518f8b436ea92deb955e81114b3f410ff7
ToppCellMacroglial-Polydendrocytes-PDGFRA|Macroglial / cells hierarchy compared to all cells using T-Statistic

COL20A1 GRIN2B PXDN PLPPR4 KCND2 TNR

6.24e-052001516c24a3099e3d96d8b72f6d05286bb355d661a0377
ToppCellMacroglial-Polydendrocytes-PDGFRA---|Macroglial / cells hierarchy compared to all cells using T-Statistic

COL20A1 GRIN2B PXDN PLPPR4 KCND2 TNR

6.24e-0520015164fc3de4bff7ed2bf40b38462c4b4e9b87af6a4ca
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA4D LRRN1 GSN TXNDC16 CDC42 MAP4K4

6.24e-052001516f0c338877e39226a90c4effe12f6501d33542a73
ToppCellParenchymal-10x3prime_v2-Stromal-Peri/Epineurial_-NAF_epineurial|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

FOXN2 COL12A1 AGPS NLN OXCT1 CSNK1G1

6.24e-052001516be46efc899d06c55ee297bee3126f69bcdb2048b
ToppCellMacroglial-Polydendrocytes-PDGFRA----L1-6|Macroglial / cells hierarchy compared to all cells using T-Statistic

COL20A1 GRIN2B PXDN PLPPR4 KCND2 TNR

6.24e-052001516310cd53db1c137f6af74e6ae682221d7ac27310c
ToppCellMacroglial-Polydendrocytes|Macroglial / cells hierarchy compared to all cells using T-Statistic

COL20A1 GRIN2B PXDN PLPPR4 KCND2 TNR

6.24e-052001516961858738ce35db8760c8c2e136f8369bc444ccf
ToppCellEntopeduncular-Macroglia-POLYDENDROCYTE|Entopeduncular / BrainAtlas - Mouse McCarroll V32

SEMA4D COL20A1 CNKSR3 FHL3 MAP4K4

1.41e-041461515a317f14a1aab11ffcce65baeb1c475c04324315f
ToppCellP28-Mesenchymal-mesenchymal_fibroblast-mesenchymal_progenitor_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

GSN KCNA2 KCNA5 KCND3 ASXL3

1.80e-04154151544d4d99b08216c0901e3bc32743fa0a8b85b5149
ToppCellPND07-28-samps-Mesenchymal-Mesothelial|PND07-28-samps / Age Group, Lineage, Cell class and subclass

MUC16 SUGCT SLC16A1 KCND3 SULF1

1.91e-041561515574f761962a7dd3308bd41fc529dd3ea1b8625f8
ToppCellPND07-28-samps-Mesenchymal-Mesothelial-Mesothelial|PND07-28-samps / Age Group, Lineage, Cell class and subclass

MUC16 SUGCT SLC16A1 KCND3 SULF1

1.91e-041561515605d95a900e1443d3f6aae163ef2e893d3293203
ToppCell3'-Adult-SmallIntestine-Epithelial-mature_enterocytic-Paneth|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NPR2 CIART CPS1 OTC SLC25A35

2.28e-041621515768a566e76923323c1f197f60bab472a8784490b
ToppCellAT1-AT2_cells-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

COL12A1 TDRD1 PXDN SULF1 CNKSR3

2.28e-04162151557d627259d27f39885bf416d74bcb6656db6e27b
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADAMTS2 SLCO1B3 GSN KCND2 SULF1

2.62e-041671515fe3338f99f94c0dac37e3d649dfdce82e4a56022
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IQSEC3 SLC2A2 AGXT2 SUGCT SLC16A1

2.70e-041681515fa0d251693935116adf633d02b7ec4a295100865
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW23-OPC_related|GW23 / Sample Type, Dataset, Time_group, and Cell type.

COL20A1 AGBL5 SLC9C2 MYO5C AASS

2.77e-04169151529db25e7c5f31d98a08a35d7ec5ade203242bc50
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW23-OPC_related-Oligodendrocyte/OPC|GW23 / Sample Type, Dataset, Time_group, and Cell type.

COL20A1 AGBL5 SLC9C2 MYO5C AASS

2.77e-041691515b1611e61f635f8f9b87250e026ad30999cbee041
ToppCellCOVID-19-lung-MAST|lung / Disease (COVID-19 only), tissue and cell type

SEMA4D PAG1 NRCAM ALS2 ITGA9

2.85e-041701515e90f18e5462381b38e918442b38b1c8105291908
ToppCell368C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

RHBDD1 LRRN1 KCND2 ARHGEF10 NFATC4

2.85e-041701515f0b0d2d0402de3ed7322284a599646db43475761
ToppCell367C-Lymphocytic-NK_cells-NK_cell_B2|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

MYO5C PXDN ARHGEF10 POFUT2 UBFD1

2.85e-041701515c1f7f1bb8865e954bb499963d82bb51923d5d8d6
ToppCell368C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

RHBDD1 LRRN1 KCND2 ARHGEF10 NFATC4

2.85e-041701515054360a3b05f5e41221c98b122d241b1affad26a
ToppCellfacs-Lung-Endomucin_-18m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA4D GRK6 ABCC5 GRAMD4 CSF1R

3.09e-041731515c31076c725f4cd912c56903592a2d9356ae59f54
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PAG1 ADAMTS2 KCNA5 KCND2 FHL3

3.09e-041731515ab6d3507301038f944ad59ccd848b5e6eeb76d04
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MUC16 AGXT2 SLC16A1 KCND2 SULF1

3.09e-04173151530d67738633493d47f06ae452424382f069b6c0a
ToppCellfacs-Lung-Endomucin_-18m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA4D GRK6 ABCC5 GRAMD4 CSF1R

3.09e-041731515a4ed191cfdf6588b7f3672995bf0a4fe9e4b8df6
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Endothelial-nan|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRIN2B ADGRL4 KCNA2 KCNA5 NOS3

3.17e-041741515fa6eb451555766398996bbe8f555a3f4c0f3c108
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Endothelial|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRIN2B ADGRL4 KCNA2 KCNA5 NOS3

3.17e-0417415151f5b0fa58b2a7335667357af7e50e5242cd13d7d
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Endothelial-endothelial_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRIN2B ADGRL4 KCNA2 KCNA5 NOS3

3.17e-041741515ac3aee6ed49d1c421f33509e3ffc5cb17750a473
ToppCellfacs-Mammary_Gland-Mammary_Gland-3m-Endothelial|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRL4 SCARF1 KCNA1 KCNA2 KCNA5

3.25e-041751515c36b4526970db9ccfbe2c70b00961fab9f13b133
ToppCellfacs-Mammary_Gland-Mammary_Gland-3m-Endothelial-endothelial_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRL4 SCARF1 KCNA1 KCNA2 KCNA5

3.25e-041751515c1e082538f31b5c98ac63f71dcca4a1211a14708
ToppCellfacs-Mammary_Gland-Mammary_Gland-3m-Endothelial-nan|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRL4 SCARF1 KCNA1 KCNA2 KCNA5

3.25e-0417515152f9b5bdf8a62e8e99d1c4f677a8e5525bfd3b4ce
ToppCellPND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MUC16 KCNA1 PLPPR4 SLC16A1 SULF1

3.34e-0417615158e7f38de8bf68077e2138f4d06c1f55b0fd096cc
ToppCellPND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MUC16 KCNA1 PLPPR4 SLC16A1 SULF1

3.34e-041761515ed575330a08a6748ea4b28433292c8cfd157d444
ToppCellCOVID-19-lung-MAST|COVID-19 / Disease (COVID-19 only), tissue and cell type

SEMA4D PAG1 NRCAM ALS2 ITGA9

3.34e-041761515473c45a381ca109207d66ed1635668b391ea0e1f
DrugPsora-4

KCNA1 KCNA2 KCNA5 KCNA7 KCND2

1.38e-08131495CID006603977
Drug4-AP

NPR2 SGCB HSPH1 GRIN2B OTC KCNA1 KCNA2 KCNA5 KCNA7 KCND2 KCND3 NOS3 HSPA8

1.60e-0825814913CID000001727
DrugAPDs

AGPS KCNA1 KCNA5 CLCN3 KCND2 KCND3 AASS

2.25e-08471497CID000016591
Drugtetraethylammonium

NPR2 SGCB AGPS CPS1 KCNA1 KCNA2 KCNA5 KCNA7 KCND2 KCND3 NOS3 SLC29A4

5.28e-0823614912CID000005413
DrugLY97241

KCNA1 KCNA2 KCNA5 KCND2

2.16e-0791494CID000175064
Drugclofilium

TCN2 KCNA1 KCNA2 KCNA5 KCNA7 KCND2 KCND3

5.57e-07741497CID000002798
Drugchromanol 293B

SGCB KCNA1 KCNA5 KCND3 NOS3

2.30e-06331495CID000121846
Drugdicyclohexyl phthalate

MBTPS1 PAG1 NPR2 GRK6 ABCC5 ALS2 MSH2 CPS1 SLC2A2 GSN PXDN CLCN3 PTGR1 NFATC4 PIK3C3 NOS3 HSPA8 SLC26A6 HTT

2.40e-0683614919ctd:C036042
Drugcis-8-octadecenoic acid

SGCB KCNA2 ANKRD11 C9

3.02e-06161494CID005282757
DrugCID10948590

KCNA1 KCNA2 KCNA5

5.41e-0661493CID010948590
DrugML-9

MBTPS1 ITGA9 GSN MEPE KCND2 KCND3 PIK3C3 CDC42

5.76e-061471498CID000004217
Drug5'-GMP Na2

NPR2 SGCB POLR2A ABCC5 ALS2 GRIN2B ITGA9 KCNA2 MAP4K4 NOS3 SLC26A6

1.35e-0533514911CID000000761
DrugK-Cl

NPR2 SGCB GART RECQL AQP6 SLC2A2 GSN MYO5C ADGRL4 NLN KCNA5 CSNK1G1 SLC25A29 NOS3

2.25e-0556714914CID000004873
DrugE 4031

KCNA1 KCNA2 KCNA5 KCND3 AASS

2.74e-05541495CID000003184
DrugIsoproterenol

TCN2 HSPH1 TDG AGBL5 CPS1 MAP3K6 ZRANB3 TSFM SBNO2 ADGRL4 KCNA5 CLCN3 KCND2 CNKSR3 LSM14A C9 MTCH2 NOS3 HSPA8

3.71e-05101614919ctd:D007545
DrugIQ-3

IQGAP1 MYO5C CDC42

4.36e-05111493CID000028212
DrugIndomethacin [53-86-1]; Down 200; 11.2uM; HL60; HT_HG-U133A

TFIP11 CPS1 TSFM EXD3 LSM14A FHL3 PCCA POFUT2

4.62e-0519614982377_DN
Drugsodium

SLC6A16 GART SLCO1B3 TDG CIT SLC2A2 AGXT2 OTC KCNA1 KCNA2 KCNA5 CLCN3 SLC16A1 KCND2 KCND3 SLC9B2 NOS3 SLC29A4

4.70e-0594414918CID000000923
DrugDyclonine hydrochloride [536-43-6]; Up 200; 12.2uM; PC3; HT_HG-U133A

VPS33A RECQL TSFM BCL11B CSF1R KCND3 ARHGEF7 SLC26A6

4.96e-0519814987261_UP
Drugmonomethyl phthalate

PAG1 NPR2 ADAMTS2 ABCC5 ALS2 MSH2 SLC2A2 GSN KCNA2 PXDN CLCN3 PTGR1 NFATC4 PIK3C3 NOS3 HSPA8 SLC26A6 HTT

5.61e-0595714918ctd:C517284
DrugNSC104956

SGCB CDC25C NOS3

5.79e-05121493CID000266508
DrugPtdIns(4)P

MBTPS1 COL20A1 GSN KCND2 PIK3C3 CDC42

6.36e-051041496CID000643965
Drugcitrullin

NPR2 SGCB CPS1 CIT OTC AASS NOS3

6.82e-051531497CID000000833
Drugpyraclofos

KCNA1 KCNA2 KCNA5 KCNA7 KCND2 KCND3

7.07e-051061496CID000093460
Drugmalonate

SEMA4D SGCB GRIN2B OXCT1 SLC25A35 AASS ACSF3 SLC29A4

7.26e-052091498CID000000867
Diseaseepilepsy (implicated_via_orthology)

NRCAM GRIN2B CIT KCNA1 KCNA2 KCNA5 KCNA7 MAP4K4 NOS3

1.02e-071631429DOID:1826 (implicated_via_orthology)
Diseaseneutrophil count

RAD51B ADAM19 ABCC5 CPS1 CIT ZRANB3 SBNO2 ADGRL4 BCL11B KCNA2 KCND3 TMEM87B CSNK1G1 CNKSR3 ANKRD11 TNR MAP4K4 HSPA8 HTT VAT1

1.08e-05138214220EFO_0004833
DiseasePrimary lateral sclerosis juvenile

ALS2 ERLIN2

2.30e-0521422C1853396
Diseaseorofacial cleft, sex interaction measurement

COL12A1 NRCAM SLCO6A1 BCL11B OSBPL5

6.12e-05861425EFO_0008343, MONDO_0000358
Diseasemethylmalonate (MMA) measurement

ANKRD11 ACSF3

1.37e-0441422EFO_0800622
DiseaseEpilepsy

GRIN2B WDR45 KCND2 ASXL3 ANKRD11

1.88e-041091425C0014544
DiseaseCHGA cleavage product measurement

RAD51B GRK6

2.28e-0451422EFO_0007909
DiseasePCSK9 protein measurement

ADGRL4 KCNA1 KCNA5

2.62e-04261423EFO_0006899
DiseaseIntellectual Disability

IQSEC3 TCN2 GRIN2B BCL11B ERLIN2 KCNA2 AASS CDC42 HTT

3.28e-044471429C3714756
DiseaseDisorder of the urea cycle metabolism

CPS1 OTC

3.41e-0461422cv:C0154246
Diseaseconduct disorder

GATAD2B KCNA1 KCNA5

4.44e-04311423EFO_0004216
DiseaseHyperammonemia

CPS1 OTC

4.75e-0471422C0220994
DiseaseParkinson's disease (is_implicated_in)

TCN2 GRK6 HSPA8 HTT

5.04e-04761424DOID:14330 (is_implicated_in)
DiseaseColorectal Carcinoma

SHANK1 ADAM19 NRCAM TCN2 ABCC5 SLCO1B3 MSH2 BCL11B SIGLEC7 KCND3 FHL3

6.10e-0470214211C0009402
DiseaseEndotoxemia

CPS1 OTC

6.32e-0481422C0376618
DiseaseSudden Cardiac Arrest

KCND2 KCND3

6.32e-0481422C1720824
DiseaseEpilepsy, Cryptogenic

GRIN2B WDR45 ASXL3 ANKRD11

6.72e-04821424C0086237
DiseaseAwakening Epilepsy

GRIN2B WDR45 ASXL3 ANKRD11

6.72e-04821424C0751111
DiseaseAura

GRIN2B WDR45 ASXL3 ANKRD11

6.72e-04821424C0236018
Diseasesialic acid-binding Ig-like lectin 9 measurement

SIGLEC12 SIGLEC7

8.10e-0491422EFO_0008286
DiseaseX-21467 measurement

SLCO1B3 CPS1

8.10e-0491422EFO_0020007
DiseaseMoyamoya disease

TCN2 NLN SUGCT

9.46e-04401423MONDO_0016820
Diseasecortical thickness

RAD51B SEMA4D NPR2 COL12A1 ADAMTS2 FAT3 GATAD2B BCL11B KCNA5 CNKSR3 STAU2 LSM14A PCCA MTCH2

9.88e-04111314214EFO_0004840
Diseaseasthma

RAD51B SEMA4D ADAM19 MUC16 SBNO2 ADGRL4 SUGCT PIK3C3 CNKSR3 ANKRD11 MAP4K4

1.06e-0375114211MONDO_0004979
DiseaseNeurodevelopmental Disorders

GRIN2B WDR45 ASXL3 ANKRD11

1.08e-03931424C1535926
DiseaseLeukoencephalopathy

TCN2 CSF1R

1.23e-03111422C0270612
Diseasegastrointestinal stromal tumor (is_implicated_in)

SLCO1B3 CSF1R

1.23e-03111422DOID:9253 (is_implicated_in)
DiseaseLiver Cirrhosis, Experimental

COL12A1 SGCB ABCC5 CPS1 GSN IQGAP1 OTC CSF1R PXDN STAU2 NOS3

1.34e-0377414211C0023893
Diseasemicrophthalmia (implicated_via_orthology)

ARHGAP6 STAU2

1.47e-03121422DOID:10629 (implicated_via_orthology)
Diseaselymphangioleiomyomatosis (is_marker_for)

SLC16A1 NOS3

1.47e-03121422DOID:3319 (is_marker_for)
Diseasesevere acute respiratory syndrome, COVID-19

GRAMD4 ARHGAP6 NLN PXDN KCND3 ARHGEF7 CNKSR3 TNR

1.50e-034471428EFO_0000694, MONDO_0100096
Diseasecholestasis (biomarker_via_orthology)

SLCO1B3 OTC NOS3

1.71e-03491423DOID:13580 (biomarker_via_orthology)
DiseaseChildhood Ataxia with Central Nervous System Hypomyelinization

TCN2 CSF1R

2.01e-03141422C1858991
Diseasecortical surface area measurement

RAD51B SEMA4D NPR2 FAT3 AGBL5 CPS1 GATAD2B BCL11B KCNA5 CNKSR3 STAU2 CDC25C PCCA MAP4K4 MTCH2

2.14e-03134514215EFO_0010736
Diseasemonoclonal gammopathy

RAD51B CPS1 CSNK1G1

2.14e-03531423EFO_0000203
DiseaseColorectal Neoplasms

NRCAM TCN2 ABCC5 SLCO1B3 MSH2 FHL3

2.29e-032771426C0009404
Diseasemyeloid cell surface antigen CD33 measurement

SIGLEC12 SIGLEC7

2.32e-03151422EFO_0008238
Diseaseureidopropionic acid measurement

PAG1 CPS1

2.64e-03161422EFO_0010542
Diseaseresponse to opioid

MUC16 MSH2 TNR

3.20e-03611423EFO_0008541
DiseaseLiver carcinoma

MAGEA6 MBTPS1 DCAF4L2 SLC2A2 IQGAP1 C9 CDC25C SLC26A6

3.25e-035071428C2239176
Diseaseessential hypertension (is_implicated_in)

NPR2 NOS3

3.35e-03181422DOID:10825 (is_implicated_in)
DiseaseAstigmatism

ADAMTS2 NLN CNKSR3 TNR

3.56e-031291424HP_0000483
Diseasediet measurement, HOMA-B

FAT3 CNKSR3

3.73e-03191422EFO_0004469, EFO_0008111
Diseasepolycystic kidney disease (biomarker_via_orthology)

C9 NOS3

3.73e-03191422DOID:0080322 (biomarker_via_orthology)
Diseaserisk-taking behaviour

SEMA4D LRRN1 ACTR10 GRIN2B HP1BP3 ADGRL4 BCL11B PCCA MTCH2 HTT

3.97e-0376414210EFO_0008579
Diseaseserum homoarginine measurement

CPS1 AGXT2

4.13e-03201422EFO_0005421
Diseaseaspartate aminotransferase measurement

PAG1 COX16 BECN2 SLCO1B3 ITGA9 SLC2A2 CSF1R CNKSR3 OSBPL5 MTCH2 VAT1

4.42e-0390414211EFO_0004736
Diseasefumarate measurement

ITGA9 CNKSR3

4.55e-03211422EFO_0010480

Protein segments in the cluster

PeptideGeneStartEntry
VPGKLSAMGLGYEDI

SUGCT

141

Q9HAC7
IEMGYGLKPSGQDSK

TDRD1

441

Q9BXT4
LPGKYGIGFTNMVER

TDG

181

Q13569
QDPGMGLKLIYYSVG

TRBV6-6

56

A0A0A6YYG2
ILMSSGPSIGIKDYN

ADGRL4

411

Q9HBW9
GLTNVGTYKMELPGG

AGXT2

206

Q9BYV1
YFSVRGGMPGKLIKI

AGBL5

76

Q8NDL9
LQGIPKVTGRGMVSY

ARHGEF10

1191

O15013
SPTMVNLLLGKGTYT

ANKRD11

276

Q6UB99
LSGKGTLTMPNGDYI

ALS2

1231

Q96Q42
LDPGLVMTGTKCGYN

ADAM19

621

Q9H013
DGKPMVLVAGQYSTG

EHD2

56

Q9NZN4
KYKVLSVLPGSGMGI

GRAMD4

521

Q6IC98
AGYEISLGLMPKSIG

AASS

201

Q9UDR5
GAMIIYTSGTTGRPK

ACSF3

196

Q4G176
RMSGFIYQGKLPTTG

ARHGEF7

516

Q14155
ETIGDAYMVVSGLPG

NPR2

906

P20594
LGYGVPMLLLIVGGS

COX16

16

Q9P0S2
VLMYEGLPGYGKSQI

ADCY10

511

Q96PN6
GLPGYGKSQILMKIE

ADCY10

516

Q96PN6
YEMLGEGLGVKETPQ

DCTN2

86

Q13561
EGYMELPDGKVLSGS

CFAP44

326

Q96MT7
PEVLTVMNGDGKGTY

CIT

266

O14578
MPLYEGLGSGGEKTA

ACTR10

1

Q9NZ32
DGKGYLAGTLAPLQM

ASXL3

1806

Q9C0F0
LSYGKSMSLIEIGNP

ADAMTS2

321

O95450
SGEKPLLGGSLMEYA

HP1BP3

331

Q5SSJ5
KYGIQMPAFSKIGGI

IQGAP1

191

P46940
GSGLTILSQPLMYVK

MTCH2

11

Q9Y6C9
TLPTNMGGLEGAVVY

RAD51B

126

O15315
KGMYLSPEGLTAVSG

RCOR2

261

Q8IZ40
LAVMYGGGPISSILV

SLC16A1

66

P53985
MTNGIKELGPYTLDR

MUC16

13106

Q8WXI7
GLMLLDRSGQGKVYP

MAP4K4

946

O95819
GYGDMVPTTIGGKIV

KCNA2

376

P16389
TTLGYGDMVPKTIAG

KCND3

366

Q9UK17
GDMYPVTIGGKIVGS

KCNA1

376

Q09470
TYVGSMPGRIINGLK

LONP2

416

Q86WA8
YDGLLGDNQVMPKTG

MAGEA2

186

P43356
YDGLLGDNQIMPKTG

MAGEA6

186

P43360
MSDPITLNVGGKLYT

KCTD21

1

Q4G0X4
IMVSAIGNDGPLYGT

MBTPS1

331

Q14703
GLRMSIYPKSTGNKG

MEPE

111

Q9NQ76
LMPGTAYKVRVGAVG

NRCAM

1126

Q92823
YGEKTGTQPQGKMEV

DTX2

476

Q86UW9
GKYNAMVLELLGPSL

CSNK1G1

111

Q9HCP0
LVPLKNGGVGIKVMY

HSPH1

91

Q92598
GSKYGIITMRGLTTP

DCAF4L2

96

Q8NA75
YLGTTTGDILKMNPR

CFAP52

221

Q8N1V2
GYLKIFMEEVPGGSL

MAP3K6

716

O95382
GGEAETKMLSQPYLL

TSFM

276

P43897
GEYLPLLQGKSLGMI

OTC

71

P00480
QGKKGVYMTDITPQG

PDZK1P1

31

A8MUH7
GLISGLVPMYIGEIA

SLC2A2

166

P11168
KYRLIVLMGPSGVGV

MPP4

426

Q96JB8
LGYGDMVPKTIAGKI

KCND2

371

Q9NZV8
MSGGTPYIGSKISLI

LSM14A

1

Q8ND56
AVTVMIGGEPYTLGL

CDC42

41

P60953
LGMPGVNIAYLNTGI

GATAD2B

546

Q8WXI9
EIGYPVMIKASAGGG

PCCA

211

P05165
PYGVITSAKVMTEGG

PABPC1L

316

Q4VXU2
AEKALMEGYGLVGLP

IQSEC3

366

Q9UPP2
GNLVDSEMKYLGSPI

CDC25C

156

P30307
VKNVPCGTSGGVMIY

ERLIN2

71

O94905
YALPAVSNMLLEIGG

NOS3

331

P29474
KGILYGTMTLELGGT

OSBPL8

576

Q9BZF1
GGSEKLYRVPGQFML

ARHGAP6

691

O43182
GDAGGIVPQYSMKLS

ITGA9

401

Q13797
LLAGGPVVAILGMIY

ABCC5

296

O15440
GLSLPYGIQVETGLM

BECN2

371

A8MW95
FTKMEYDGILIAGGP

CPS1

251

P31327
GEGLNLKVMVEAYPG

CSF1R

316

P07333
ETVMPGSRKLEYGGQ

FHL3

106

Q13643
INPERELGSMSYKLG

HTT

2601

P42858
VGYGDMRPITVGGKI

KCNA5

481

P22460
YGDMAPVTVGGKIVG

KCNA7

361

Q96RP8
GKVMENVGLGALPQY

BCL11B

596

Q9C0K0
LPIYKMGEGKLRQGS

COL12A1

1066

Q99715
ATVGAALLYGVMPGD

AQP6

111

Q13520
GSGLGYLVQVKPMAG

COL20A1

51

Q9P218
IPVYSLMAKATDGGG

FAT3

3096

Q8TDW7
KYLMLGQQAVGGVPI

CEP85L

276

Q5SZL2
LGLYKGLGSPLMGLT

SLC25A29

56

Q8N8R3
IAGLSQIYKMGSLPE

FOXN2

21

P32314
GKPMIIYKGGTSREG

GSN

541

P06396
TIKGRVGTVGYMAPE

GRK6

341

P43250
QPTDAQGKGLMYRGI

SLC25A35

236

Q3KQZ1
VMPEYRGQGIGSKII

SAT2

96

Q96F10
IITGPNMGGKSTYIR

MSH2

666

P43246
AGYGINILGMDPLST

C9

156

P02748
VLAGMYLTDIPGNAL

LRRN1

221

Q6UXK5
SLALGTVGMPGLTAY

PTGR1

116

Q14914
MSKGPAVGIDLGTTY

HSPA8

1

P11142
IITKLYQSAGGMPGG

HSPA8

606

P11142
GILYGTMTLELGGKV

OSBPL5

541

Q9H0X9
DYQLTGQPVLIGGTM

RTCB

391

Q9Y3I0
KPTLAEMGCYGLGVT

PARS2

331

Q7L3T8
GIGLGSVASLASYMP

SLC6A16

351

Q9GZN6
LAGILVGLMYTQGPL

RHBDD1

196

Q8TEB9
VRMGLTQPKGVLLYG

SPATA5L1

491

Q9BVQ7
GYSEKPLTLQMFIGT

NFATC4

456

Q14934
MKVKLGSALGGPYLG

POFUT2

276

Q9Y2G5
TLIGATGISYGMGLK

SLC26A6

301

Q9BXS9
PVGGTTVSLFGKYGM

PIK3C3

121

Q8NEB9
SVYAAMEQGLLPAGL

EPPK1

56

P58107
PSMLLLQGGGYGVEK

SLC9B2

251

Q86UD5
YGVEKGVPTLLMAAG

SLC9B2

261

Q86UD5
YTGKMRPVSGVLLGA

SIGLEC7

341

Q9Y286
QTVQGIAGMPLYILG

SLCO6A1

236

Q86UG4
GGSVLGGYLKILPMF

SLC5A9

316

Q2M3M2
EGKYDMGILDLAPGI

SBNO2

1001

Q9Y2G9
LIITGPNMSGKSTYL

MSH4

676

O15457
ALARVGKVGPMIGQY

WDR45

276

Q9Y484
GMYANLGIGIPLLAS

OXCT1

316

P55809
NGVLKAESPKYGLMG

SEMA4D

591

Q92854
MGVIHPLYKSTVGGR

SGCB

116

Q16585
GLGMEGPYEVLKDSS

PAG1

156

Q9NWQ8
EYTGKMRPISGVTLG

SIGLEC12

466

Q96PQ1
SSIGGTLYEVGKPEM

SRBD1

841

Q8N5C6
GPVTTIYMLAGKPRG

SCARF1

686

Q14162
SLMDGIGPGSDYIIK

SHANK1

646

Q9Y566
LSGPYLTSVMGKAAG

TCN2

376

P20062
IELTGKRYPLSGMGL

AGPS

111

O00116
FSKGLPISMYGGTII

ANKHD1

2466

Q8IWZ3
GVLQKPQMGERYLGT

CIART

166

Q8N365
MSSVYSAKLGPVGGI

LINC00615

21

Q96LM1
LIIGQAEGPGSYIMN

CLCN3

196

P51790
NIKPGEGLGMYIKST

CNK3/IPCEF1

216

G9CGD6
NIKPGEGLGMYIKST

CNKSR3

216

Q6P9H4
VGMKYRNLILKPGGS

NLN

661

Q9BYT8
LVMPTGGGKSLCYQL

RECQL

111

P46063
AGPAITIMVGEGILY

PLPPR4

131

Q7Z2D5
KKGENPVSYAGMLGT

TXNDC16

471

Q9P2K2
VPLSGMYNKSGGKVR

UBFD1

216

O14562
NDEMLSYLPGGTTGL

TFE3

276

P19532
ISGTTLGYLSPKDMN

STAU2

431

Q9NUL3
PVGGLLMAFQKYSGE

TIMMDC1

201

Q9NPL8
KYGMEIPTNIPGLGA

POLR2A

1481

P24928
SLYLGSLNAIGMIGP

SLCO1B3

206

Q9NPD5
PKILGEVGMRTLGEY

PXDN

1036

Q92626
LVPGTEYGVGISAVM

TNR

656

Q92752
GILYAGIMLTKNGPK

GART

271

P22102
PMGGYGKTISHVIIG

RUVBL1

146

Q9Y265
AMLEKYGTVVSLGLP

ZNF446

226

Q9NWS9
SLGYGIVKPRLGTVM

TMEM87B

306

Q96K49
GSDTAKGYNLLKPMG

VAT1

266

Q99536
GYFGSVPMILAAGKV

SLC29A4

461

Q7RTT9
KGGEMPQGIYLIISG

SLC9C2

896

Q5TAH2
AKGLMTLQALYGTIP

VPS33A

176

Q96AX1
IGQFGLVKGKSMPYD

SULF1

321

Q8IWU6
GIGQKLLQKMGYVPG

TFIP11

151

Q9UBB9
MGLGKTIQAIGITYF

ZRANB3

61

Q5FWF4
GGTNQGLLPYLMALD

NLRP13

11

Q86W25
MLEYESLQGISGLKP

MYO5C

1516

Q9NQX4
QLLSDPSITKLGYGM

EXD3

451

Q8N9H8
PSITKLGYGMVGDLQ

EXD3

456

Q8N9H8
GKPGMVFSISRGIYS

GRIN2B

856

Q13224