Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessmeiotic telomere clustering

TERB1 ATM MEI1

2.73e-0514893GO:0045141
GeneOntologyBiologicalProcesschromosome localization to nuclear envelope involved in homologous chromosome segregation

TERB1 ATM MEI1

2.73e-0514893GO:0090220
GeneOntologyBiologicalProcesstelomere localization

TERB1 ATM MEI1

3.40e-0515893GO:0034397
GeneOntologyBiologicalProcesspositive regulation of T cell extravasation

CCR2 MED23

1.10e-044892GO:2000409
GeneOntologyBiologicalProcessmeiotic cell cycle

M1AP SLC26A8 TERB1 MCM3 MCM4 ATM MEI1 HORMAD1

1.36e-04350898GO:0051321
GeneOntologyBiologicalProcessmeiotic cell cycle process

M1AP TERB1 MCM3 MCM4 ATM MEI1 HORMAD1

1.61e-04268897GO:1903046
GeneOntologyBiologicalProcessmitotic DNA replication initiation

MCM3 MCM4

1.83e-045892GO:1902975
GeneOntologyBiologicalProcessnuclear cell cycle DNA replication initiation

MCM3 MCM4

1.83e-045892GO:1902315
GeneOntologyBiologicalProcesscell cycle DNA replication initiation

MCM3 MCM4

1.83e-045892GO:1902292
GeneOntologyBiologicalProcessmeiotic chromosome segregation

M1AP TERB1 ATM MEI1 HORMAD1

1.86e-04122895GO:0045132
GeneOntologyBiologicalProcesspremeiotic DNA replication

MCM3 MCM4

2.73e-046892GO:0006279
GeneOntologyBiologicalProcessregulation of T cell extravasation

CCR2 MED23

2.73e-046892GO:2000407
GeneOntologyBiologicalProcesschromosome organization involved in meiotic cell cycle

TERB1 ATM MEI1 HORMAD1

3.12e-0475894GO:0070192
GeneOntologyBiologicalProcesshomologous chromosome segregation

TERB1 ATM MEI1 HORMAD1

3.62e-0478894GO:0045143
GeneOntologyBiologicalProcessinorganic ion import across plasma membrane

SLC12A6 SLC9A3 SLC9A5 NALF1 KCNJ9

3.76e-04142895GO:0099587
GeneOntologyBiologicalProcessinorganic cation import across plasma membrane

SLC12A6 SLC9A3 SLC9A5 NALF1 KCNJ9

3.76e-04142895GO:0098659
GeneOntologyBiologicalProcessadenylate cyclase-inhibiting serotonin receptor signaling pathway

HTR1D HTR1F

3.81e-047892GO:0007198
GeneOntologyCellularComponentperinuclear region of cytoplasm

CCR2 LGMN NELL1 ABCA1 MYO9B VPS33A PKHD1 MCM3 ROS1 FLRT1 RYR3 MAPK8IP3 EPG5

1.57e-049348913GO:0048471
MousePhenoabnormal synaptic transmission

SLC12A6 PRKD2 LGMN CNTNAP5 HTR1F TSPOAP1 NETO1 KCNJ9 SCN8A CNGA2 DDC DSCAML1 FAM135B RYR3 ZNF260 MAPK8IP3 EPG5 COPS7A

5.51e-0610707218MP:0003635
MousePhenoabnormal synaptic physiology

SLC12A6 PRKD2 LGMN CNTNAP5 HTR1F TSPOAP1 NETO1 KCNJ9 SCN8A CNGA2 DDC DSCAML1 FAM135B RYR3 ZNF260 MAPK8IP3 EPG5 COPS7A

5.96e-0610767218MP:0021009
DomainARM-type_fold

FOCAD URB1 RTTN TERB1 PPP6R1 ATM MEI1 WDFY4 EIF3M RYR3

4.85e-063398910IPR016024
DomainNa/H_exchanger_3/5

SLC9A3 SLC9A5

2.25e-052892IPR018410
DomainMCM_N

MCM3 MCM4

3.33e-046892IPR027925
DomainMCM_N

MCM3 MCM4

3.33e-046892PF14551
DomainMCM_CS

MCM3 MCM4

3.33e-046892IPR018525
DomainSec1

VPS33A SCFD1

6.17e-048892PF00995
DomainSec1-like

VPS33A SCFD1

6.17e-048892IPR001619
DomainMCM_OB

MCM3 MCM4

6.17e-048892IPR033762
Domain-

VPS33A SCFD1

6.17e-0488923.40.50.1910
DomainMCM_2

MCM3 MCM4

6.17e-048892PS50051
DomainMCM_1

MCM3 MCM4

6.17e-048892PS00847
DomainSec-1-like_dom2

VPS33A SCFD1

6.17e-048892IPR027482
DomainMCM_OB

MCM3 MCM4

6.17e-048892PF17207
DomainMCM

MCM3 MCM4

7.91e-049892SM00350
DomainNaH_exchanger

SLC9A3 SLC9A5

7.91e-049892IPR004709
DomainMCM_dom

MCM3 MCM4

7.91e-049892IPR001208
DomainMCM

MCM3 MCM4

7.91e-049892IPR031327
DomainMCM

MCM3 MCM4

7.91e-049892PF00493
Domain5HT_rcpt

HTR1D HTR1F

7.91e-049892IPR002231
DomainLaminin_G_2

NELL1 CNTNAP5 LAMA5

9.10e-0440893PF02210
DomainCation/H_exchanger_CPA1

SLC9A3 SLC9A5

1.20e-0311892IPR018422
DomainLamG

NELL1 CNTNAP5 LAMA5

1.20e-0344893SM00282
DomainNa_H_Exchanger

SLC9A3 SLC9A5

1.97e-0314892PF00999
DomainCation/H_exchanger

SLC9A3 SLC9A5

1.97e-0314892IPR006153
DomainuDENN

DENND4B DENND5A

1.97e-0314892SM00800
DomainuDENN

DENND4B DENND5A

2.26e-0315892PF03456
DomainUDENN

DENND4B DENND5A

2.58e-0316892PS50946
DomainDDENN

DENND4B DENND5A

2.58e-0316892PS50947
DomainDENN

DENND4B DENND5A

2.58e-0316892SM00799
DomaindDENN

DENND4B DENND5A

2.58e-0316892SM00801
DomainDENN

DENND4B DENND5A

2.58e-0316892PF02141
DomaindDENN_dom

DENND4B DENND5A

2.58e-0316892IPR005112
DomainuDENN_dom

DENND4B DENND5A

2.58e-0316892IPR005113
DomaindDENN

DENND4B DENND5A

2.58e-0316892PF03455
DomainDENN

DENND4B DENND5A

2.58e-0316892PS50211
DomainDENN_dom

DENND4B DENND5A

2.58e-0316892IPR001194
DomainPINT

EIF3M COPS7A

2.58e-0316892SM00088
DomainLaminin_G

NELL1 CNTNAP5 LAMA5

2.67e-0358893IPR001791
DomainPCI_dom

EIF3M COPS7A

2.91e-0317892IPR000717
DomainPCI

EIF3M COPS7A

2.91e-0317892PF01399
DomainWD40_repeat_dom

SEH1L FBXW10B FBXW10 HERC1 WDFY4 MAPK8IP3

2.96e-03297896IPR017986
DomainConA-like_dom

NELL1 CNTNAP5 LAMA5 HERC1 RYR3

3.96e-03219895IPR013320
DomainRCC1

MYCBP2 HERC1

4.03e-0320892PF00415
DomainRCC1_1

MYCBP2 HERC1

4.45e-0321892PS00625
DomainRCC1_2

MYCBP2 HERC1

4.45e-0321892PS00626
DomainRCC1_3

MYCBP2 HERC1

4.45e-0321892PS50012
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

FOCAD URB1 DENND4B KCNJ9 CDIPT SCN8A PKHD1 PPP6R1 ATM CNOT1 DSCAML1

3.23e-06736901129676528
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

FOCAD PRKD2 URB1 MYCBP2 MYO9B ARHGAP26 RTTN SCN8A LAMA5 PPP6R1 DENND5A HERC1 MAPK8IP3

5.35e-061105901335748872
Pubmed

FBXW10 promotes hepatocarcinogenesis in male patients and mice.

FBXW10B FBXW10

6.62e-06290231400758
Pubmed

Identification of carboxyl-terminal MCM3 phosphorylation sites using polyreactive phosphospecific antibodies.

MCM3 ATM

6.62e-06290217244605
Pubmed

Elevated FBXW10 drives hepatocellular carcinoma tumorigenesis via AR-VRK2 phosphorylation-dependent GAPDH ubiquitination in male transgenic mice.

FBXW10B FBXW10

6.62e-06290237450367
Pubmed

MCM4 mutation causes adrenal failure, short stature, and natural killer cell deficiency in humans.

MCM3 MCM4

6.62e-06290222354170
Pubmed

Association study of the serotoninergic system in migraine in the Spanish population.

HTR1D HTR1F DDC

1.33e-051890319455600
Pubmed

A human homologue of the yeast replication protein Cdc21. Interactions with other Mcm proteins.

MCM3 MCM4

1.98e-0539027601140
Pubmed

5-Hydroxytryptamine(1B/1D) and 5-hydroxytryptamine1F receptors inhibit capsaicin-induced c-fos immunoreactivity within mouse trigeminal nucleus caudalis.

HTR1D HTR1F

1.98e-05390212110114
Pubmed

Down-regulation of CK2α correlates with decreased expression levels of DNA replication minichromosome maintenance protein complex (MCM) genes.

MCM3 MCM4

1.98e-05390231601942
Pubmed

Molecular cloning of cDNA encoding mouse Cdc21 and CDC46 homologs and characterization of the products: physical interaction between P1(MCM3) and CDC46 proteins.

MCM3 MCM4

1.98e-0539027610039
Pubmed

Silencing of p29 affects DNA damage responses with UV irradiation.

CCNDBP1 MCM3

1.98e-05390216951160
Pubmed

Properties of the human nuclear protein p85Mcm. Expression, nuclear localization and interaction with other Mcm proteins.

MCM3 MCM4

1.98e-0539028631321
Pubmed

Expression mapping of 5-HT1 serotonin receptor subtypes during fetal and early postnatal mouse forebrain development.

HTR1D HTR1F

3.96e-05490216824687
Pubmed

Mouse cdc21 only 0.5 kb upstream from dna-pkcs in a head-to-head organization: an implication of co-evolution of ATM family members and cell cycle regulating genes.

MCM4 ATM

3.96e-0549029716665
Pubmed

Genetic factors for ischemic and hemorrhagic stroke in Japanese individuals.

ABCA1 ROS1

3.96e-05490218566305
Pubmed

The P1 family: a new class of nuclear mammalian proteins related to the yeast Mcm replication proteins.

MCM3 MCM4

3.96e-0549028265339
Pubmed

FBXW10-S6K1 promotes ANXA2 polyubiquitination and KRAS activation to drive hepatocellular carcinoma development in males.

FBXW10B FBXW10

6.59e-05590237277019
Pubmed

Incremental genetic perturbations to MCM2-7 expression and subcellular distribution reveal exquisite sensitivity of mice to DNA replication stress.

MCM3 MCM4

6.59e-05590220838603
Pubmed

The pathological consequences of impaired genome integrity in humans; disorders of the DNA replication machinery.

MCM3 MCM4

6.59e-05590227757957
Pubmed

Role of DNA damage response pathways in preventing carcinogenesis caused by intrinsic replication stress.

MCM4 ATM

6.59e-05590223975433
Pubmed

Pairwise interactions of the six human MCM protein subunits.

MCM3 MCM4

9.87e-05690215236977
Pubmed

Human Mcm proteins at a replication origin during the G1 to S phase transition.

MCM3 MCM4

9.87e-05690212364596
Pubmed

Highly stable loading of Mcm proteins onto chromatin in living cells requires replication to unload.

MCM3 MCM4

9.87e-05690221220507
Pubmed

Association of polymorphisms of ABCA1 and ROS1 with hypertension in Japanese individuals.

ABCA1 ROS1

9.87e-05690218097620
Pubmed

Minichromosome maintenance proteins are direct targets of the ATM and ATR checkpoint kinases.

MCM3 ATM

9.87e-05690215210935
Pubmed

Basal level of FANCD2 monoubiquitination is required for the maintenance of a sufficient number of licensed-replication origins to fire at a normal rate.

MCM3 MCM4

9.87e-05690224658369
Pubmed

LRRK2 and the stress response: interaction with MKKs and JNK-interacting proteins.

MAP2K3 MAPK8IP3

9.87e-05690220173330
Pubmed

The eukaryotic Mcm2-7 replicative helicase.

MCM3 MCM4

9.87e-05690222918583
Pubmed

In vivo interaction of human MCM heterohexameric complexes with chromatin. Possible involvement of ATP.

MCM3 MCM4

9.87e-0569029099751
Pubmed

5-hydroxytryptamine synthesized in the aorta-gonad-mesonephros regulates hematopoietic stem and progenitor cell survival.

HTR1D HTR1F DDC

1.03e-043590328031476
Pubmed

O-GlcNAc transferase associates with the MCM2-7 complex and its silencing destabilizes MCM-MCM interactions.

MCM3 MCM4

1.38e-04790230069701
Pubmed

Suicide and serotonin: study of variation at seven serotonin receptor genes in suicide completers.

HTR1D HTR1F

1.38e-04790212627464
Pubmed

Identification of two residues in MCM5 critical for the assembly of MCM complexes and Stat1-mediated transcription activation in response to IFN-gamma.

MCM3 MCM4

1.38e-04790211248027
Pubmed

Identification and characterization of a novel component of the human minichromosome maintenance complex.

MCM3 MCM4

1.38e-04790217296731
Pubmed

Interaction of chromatin-associated Plk1 and Mcm7.

MCM3 MCM4

1.38e-04790215654075
Pubmed

Calcineurin homologous protein isoform 2 (CHP2), Na+/H+ exchangers-binding protein, is expressed in intestinal epithelium.

SLC9A3 SLC9A5

1.38e-04790212576672
Pubmed

Novel triplet repeat containing genes in human brain: cloning, expression, and length polymorphisms.

NALF1 DENND4B

1.38e-0479028325628
Pubmed

Binding of human minichromosome maintenance proteins with histone H3.

MCM3 MCM4

1.38e-0479028798650
Pubmed

NHE1 is the sodium-hydrogen exchanger active in acute intracellular pH regulation in preimplantation mouse embryos.

SLC9A3 SLC9A5

1.38e-04790223677982
Pubmed

A directed protein interaction network for investigating intracellular signal transduction.

FOCAD PRKD2 URB1 TMEM98 MYO9B CDIPT PARVA MCM3 PPP6R1 DENND5A MAP2K3

1.55e-041124901121900206
Pubmed

Mapping the Genetic Landscape of Human Cells.

SEH1L MCM3 MCM4 MED23 RRM1 CNOT1 EIF3M

1.74e-0445190730033366
Pubmed

Female-biased embryonic death from inflammation induced by genomic instability.

MCM3 MCM4

1.84e-04890230787433
Pubmed

5-hydroxytryptamine produced by enteric serotonergic neurons initiates colorectal cancer stem cell self-renewal and tumorigenesis.

HTR1D HTR1F

1.84e-04890235550066
Pubmed

FANCD2 binds MCM proteins and controls replisome function upon activation of s phase checkpoint signaling.

MCM3 MCM4

1.84e-04890223993743
Pubmed

Microarray gene expression analysis of tumorigenesis and regional lymph node metastasis in laryngeal squamous cell carcinoma.

MCM3 MCM4

1.84e-04890224386425
Pubmed

Essential role of phosphorylation of MCM2 by Cdc7/Dbf4 in the initiation of DNA replication in mammalian cells.

MCM3 MCM4

1.84e-04890216899510
Pubmed

Mouse HORMAD1 is a meiosis i checkpoint protein that modulates DNA double- strand break repair during female meiosis.

ATM HORMAD1

1.84e-04890223759310
Pubmed

Human Cdc7-related kinase complex. In vitro phosphorylation of MCM by concerted actions of Cdks and Cdc7 and that of a criticial threonine residue of Cdc7 bY Cdks.

MCM3 MCM4

2.36e-04990210846177
Pubmed

The interaction between checkpoint kinase 1 (Chk1) and the minichromosome maintenance (MCM) complex is required for DNA damage-induced Chk1 phosphorylation.

MCM3 MCM4

2.36e-04990225049228
Pubmed

L3MBTL1 polycomb protein, a candidate tumor suppressor in del(20q12) myeloid disorders, is essential for genome stability.

MCM3 MCM4

2.36e-04990221149733
Pubmed

Trafficking machinery of NKT cells: shared and differential chemokine receptor expression among V alpha 24(+)V beta 11(+) NKT cell subsets with distinct cytokine-producing capacity.

CXCR5 CCR2

2.36e-04990212070001
Pubmed

Keap1-MCM3 interaction is a potential coordinator of molecular machineries of antioxidant response and genomic DNA replication in metazoa.

MCM3 MCM4

2.36e-04990230108253
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

GOLPH3L MYCBP2 VPS33A SCN8A MCM3 CNOT1 CAP1 EPG5 DNAH1

2.47e-0480790930575818
Pubmed

A genome-wide camptothecin sensitivity screen identifies a mammalian MMS22L-NFKBIL2 complex required for genomic stability.

MCM3 MCM4

2.94e-041090221055985
Pubmed

Embryonic expression and function of the chemokine SDF-1 and its receptor, CXCR4.

CXCR5 CCR2

2.94e-041090210479460
Pubmed

Renalase regulates renal dopamine and phosphate metabolism.

SLC9A3 DDC

2.94e-041090223863468
Pubmed

Functional cooperation between FACT and MCM helicase facilitates initiation of chromatin DNA replication.

MCM3 MCM4

2.94e-041090216902406
Pubmed

Mouse HORMAD1 and HORMAD2, two conserved meiotic chromosomal proteins, are depleted from synapsed chromosome axes with the help of TRIP13 AAA-ATPase.

ATM HORMAD1

2.94e-041090219851446
Pubmed

MEI4 – a central player in the regulation of meiotic DNA double-strand break formation in the mouse.

MEI1 HORMAD1

3.59e-041190225795304
Pubmed

Temporal Regulation of ESCO2 Degradation by the MCM Complex, the CUL4-DDB1-VPRBP Complex, and the Anaphase-Promoting Complex.

MCM3 MCM4

3.59e-041190230100344
Pubmed

NOTCH1 nuclear interactome reveals key regulators of its transcriptional activity and oncogenic function.

MCM3 PPP6R1 MED23 CNOT1

3.61e-0412990423022380
Pubmed

Interaction of human minichromosome maintenance protein-binding protein with minichromosome maintenance 2-7.

MCM3 MCM4

4.30e-041290224299456
Pubmed

A Liver Capsular Network of Monocyte-Derived Macrophages Restricts Hepatic Dissemination of Intraperitoneal Bacteria by Neutrophil Recruitment.

CXCR5 CCR2

4.30e-041290228813662
Pubmed

Properties of the human Cdc45/Mcm2-7/GINS helicase complex and its action with DNA polymerase epsilon in rolling circle DNA synthesis.

MCM3 MCM4

4.30e-041290222474384
Pubmed

Interactions of the human MCM-BP protein with MCM complex components and Dbf4.

MCM3 MCM4

5.07e-041390222540012
Pubmed

Ionizing radiation-induced gene modulations, cytokine content changes and telomere shortening in mouse fetuses exhibiting forelimb defects.

ATM MAP2K3

5.07e-041390218722365
Pubmed

Protein interaction and cellular localization of human CDC45.

MCM3 MCM4

5.07e-041390223364835
Pubmed

A genome-wide association study on common SNPs and rare CNVs in anorexia nervosa.

HTR1D NALF1

5.07e-041390221079607
Pubmed

Hormad1 mutation disrupts synaptonemal complex formation, recombination, and chromosome segregation in mammalian meiosis.

ATM HORMAD1

5.91e-041490221079677
Pubmed

The laminin alpha chains: expression, developmental transitions, and chromosomal locations of alpha1-5, identification of heterotrimeric laminins 8-11, and cloning of a novel alpha3 isoform.

LAMA5 ROS1

5.91e-04149029151674
Pubmed

Mouse chromosomal location of four Na/H exchanger isoform genes.

SLC9A3 HTR1D

5.91e-04149028824815
Pubmed

Phosphorylation of chromosome core components may serve as axis marks for the status of chromosomal events during mammalian meiosis.

ATM HORMAD1

5.91e-041490222346761
Pubmed

SENP3 regulates the global protein turnover and the Sp1 level via antagonizing SUMO2/3-targeted ubiquitination and degradation.

MCM3 MCM4 RRM1

6.23e-046490326511642
Pubmed

Association of genetic variants with chronic kidney disease in individuals with different lipid profiles.

CCR2 SLC26A8 ABCA1 ROS1

6.69e-0415290419578796
Pubmed

Mutations that affect meiosis in male mice influence the dynamics of the mid-preleptotene and bouquet stages.

ATM MEI1

6.80e-041590217010969
Pubmed

The Cdc6 nucleotide-binding site regulates its activity in DNA replication in human cells.

MCM3 MCM4

6.80e-041590210436018
Pubmed

MCM10 mediates RECQ4 association with MCM2-7 helicase complex during DNA replication.

MCM3 MCM4

6.80e-041590219696745
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

SEH1L URB1 MYCBP2 MYO9B MCM3 MCM4 SCFD1 RRM1 MAP2K3 EIF3M CAP1

7.40e-041353901129467282
Pubmed

The human homolog of Saccharomyces cerevisiae Mcm10 interacts with replication factors and dissociates from nuclease-resistant nuclear structures in G(2) phase.

MCM3 MCM4

7.76e-041690211095689
Pubmed

Tissue distribution, ontogeny, and hormonal regulation of xenobiotic transporters in mouse kidneys.

ABCA1 SLC29A3

7.76e-041690219679677
Pubmed

Association analyses identify three susceptibility Loci for vitiligo in the Chinese Han population.

CXCR5 SLC29A3

8.78e-041790222951725
Pubmed

Identification of proteins that may directly interact with human RPA.

MCM3 MCM4

8.78e-041790220679368
Pubmed

HIV-1 Nef down-modulates C-C and C-X-C chemokine receptors via ubiquitin and ubiquitin-independent mechanism.

CXCR5 CCR2

8.78e-041790224489825
Pubmed

DNA replication in eukaryotic cells.

MCM3 MCM4

9.86e-041890212045100
Pubmed

Genome-wide association study identifies genetic risk underlying primary rhegmatogenous retinal detachment.

GOLPH3L HORMAD1

9.86e-041890223585552
Pubmed

Macropinocytosis and TAK1 mediate anti-inflammatory to pro-inflammatory macrophage differentiation by HIV-1 Nef.

SLC9A3 SLC9A5

9.86e-041890224874739
Pubmed

Human claspin is a ring-shaped DNA-binding protein with high affinity to branched DNA structures.

MCM3 MCM4

1.10e-031990215226314
Pubmed

Defining the human deubiquitinating enzyme interaction landscape.

SEH1L PRKD2 LGMN MYCBP2 MCM4 PPP6R1 CNOT1 EIF3M COPS7A

1.18e-03100590919615732
Pubmed

Transcription factors SOX4 and SOX9 cooperatively control development of bile ducts.

LAMA5 CPS1

1.22e-032090226033091
Pubmed

Multiple roles of lymphatic vessels in peripheral lymph node development.

CXCR5 LAMA5

1.22e-032090230355615
Pubmed

Interaction and assembly of murine pre-replicative complex proteins in yeast and mouse cells.

MCM3 MCM4

1.22e-032090212614612
Pubmed

Dissociation of heterotrimeric g proteins in cells.

CXCR5 CCR2 HTR1D HTR1F

1.23e-0317990418577758
Pubmed

A mouse knockout library for secreted and transmembrane proteins.

TRHDE SLC29A3 TMEM98 SIGIRR FLRT1 FGF19

1.27e-0346090620562862
Pubmed

A multiprotein complex necessary for both transcription and DNA replication at the β-globin locus.

MCM3 MCM4

1.35e-032190220808282
Pubmed

A Cxcl12-CXCR4 chemokine signaling pathway defines the initial trajectory of mammalian motor axons.

CXCR5 CCR2

1.35e-032190216129397
Pubmed

Repression of cyclin D1 expression is necessary for the maintenance of cell cycle exit in adult mammalian cardiomyocytes.

MCM3 MCM4

1.35e-032190224821722
Pubmed

CIF-1, a shared subunit of the COP9/signalosome and eukaryotic initiation factor 3 complexes, regulates MEL-26 levels in the Caenorhabditis elegans embryo.

EIF3M COPS7A

1.35e-032190217403899
Pubmed

Importance of EGFR/ERCC1 interaction following radiation-induced DNA damage.

MCM3 MCM4

1.48e-032290224780295
Pubmed

DNA-dependent phosphorylation of Chk1 and Claspin in a human cell-free system.

MCM3 MCM4

1.48e-032290215707391
Cytoband15q14-q15

CCNDBP1 RYR3

3.70e-05589215q14-q15
Cytoband18q22.2

NETO1 RTTN

7.75e-05789218q22.2
CytobandEnsembl 112 genes in cytogenetic band chr11p15

NELL1 OR51D1 SIGIRR PARVA OR2D2 DENND5A RRM1

1.18e-04564897chr11p15
Cytoband14q32.11

NRDE2 DGLUCY

4.96e-041789214q32.11
GeneFamilyMCM family

MCM3 MCM4

3.11e-0495421085
GeneFamilyWD repeat domain containing|F-box and WD repeat domain containing

FBXW10B FBXW10

4.73e-0411542559
GeneFamily5-hydroxytryptamine receptors, G protein-coupled

HTR1D HTR1F

6.69e-0413542170
GeneFamilyWD repeat domain containing

SEH1L FBXW10B FBXW10 HERC1 WDFY4

1.09e-03262545362
GeneFamilyFibronectin type III domain containing

TSPOAP1 ROS1 FLRT1 DSCAML1

1.32e-03160544555
GeneFamilyGuanylate cyclase receptors|DENN/MADD domain containing

DENND4B DENND5A

2.51e-0325542504
GeneFamilyTaste 2 receptors

TAS2R33 TAS2R19

6.04e-03395421162
GeneFamilySolute carriers

SLC12A6 SLC26A8 SLC29A3 SLC9A3 SLC9A5

6.38e-03395545752
GeneFamilyGATA zinc finger domain containing|Myb/SANT domain containing

TERB1 ZKSCAN2

1.09e-0253542532
CoexpressionAtlasCD positive, CD19 Control, 19+ 4- 8-, Spleen, avg-6

CXCR5 SLC12A6 PRKD2 LGMN ABCA1 FCRL3 ARHGAP26 WDFY4

5.41e-05339838GSM403988_500
CoexpressionAtlasB cells, B.Fo.Sp, IgD+ IgM+ CD45R+ CD24+ CD19+ AA4.1- CD23+, Spleen, avg-3

CXCR5 SLC12A6 PRKD2 LGMN ABCA1 FCRL3 ARHGAP26 WDFY4

6.12e-05345838GSM538201_500
CoexpressionAtlasB cells, B.T3.Sp, IgD+ IgM+ CD45R+ CD24+ CD19+ AA4.1+ CD23+, Spleen, avg-3

CXCR5 SLC12A6 PRKD2 LGMN ABCA1 FCRL3 ARHGAP26 WDFY4

8.40e-05361838GSM538219_500
CoexpressionAtlasB cells, B.FrF.BM, CD19+ IgM+ AA4.1- HSA+, Bone marrow, avg-3

CXCR5 SLC12A6 PRKD2 LGMN ABCA1 FCRL3 ARHGAP26 WDFY4

9.41e-05367838GSM399440_500
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRHDE PKHD1 ROS1 CPS1 DSCAML1 RYR3 DNAH1

8.86e-081848972cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRHDE PKHD1 ROS1 CPS1 DSCAML1 RYR3 DNAH1

8.86e-08184897ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRHDE PKHD1 ROS1 CPS1 DSCAML1 RYR3 DNAH1

8.86e-081848972b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellControl-B_activate-7|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

FBXW10B DGLUCY TSPOAP1 SCN8A TAS2R19

3.50e-06115895cc2f8fb0cbb72b241b65a69195aac0507bddf2e2
ToppCellfacs-Marrow-B-cells-24m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC29A3 NALF1 TMEM221 ROS1 FGF19

1.01e-051438956df16bf0324661cd9707df69cb39f4b5498d6d49
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_B-B_cell-B_c04-SOX5-TNFRSF1B|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

FCRL3 HIPK4 NETO1 FRMPD3 WDFY4

1.05e-05144895fca32b38d23fa4d213e553b929604a2796e9a929
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRHDE PKHD1 CPS1 DSCAML1 RYR3

1.74e-05160895c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRHDE PKHD1 CPS1 DSCAML1 RYR3

1.74e-0516089525c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellPND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCR2 CYSLTR2 MCM3 MCM4 RRM1

2.14e-05167895859dfe0764cb69de27e79e1c1aa65f9d538f79ea
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_B|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CXCR5 CCR2 FCRL3 MEI1 WDFY4

2.54e-0517389562ba49c1c16760a8c6cde0cc44e068f94386946a
ToppCellfacs-Marrow-B-cells-24m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRHDE LGMN NETO1 PKHD1 FGF19

2.68e-05175895887e75fc90e59a6394d62f3c048a9cfdf6707725
ToppCellChildren_(3_yrs)-Immune-B_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

CXCR5 FCRL3 NETO1 FRMPD3 WDFY4

3.07e-0518089540a12eb852373ae3d7c8d9bca376b0ae99f724b3
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Lymphocytic_B|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CXCR5 FCRL3 NETO1 MEI1 WDFY4

3.07e-0518089565c069585737302a69b9a01476f4eb8b50cb2bfd
ToppCellnucseq-Immune-Lymphocytic_B-Lymphocytic_B-B|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

FCRL3 MYCBP2 NETO1 ATM WDFY4

3.15e-051818958d8cc4dae2c8bd5f4b1c159f2a52edc4c9449c86
ToppCellMild/Remission-B_intermediate-10|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

FCRL3 TSPOAP1 NETO1 MYO9B WDFY4

3.32e-05183895278064c9f0582463b83bf156d34e77f60187613b
ToppCelldroplet-Lung-3m-Epithelial-airway_epithelial-neuroendocrine_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SCN8A ZKSCAN2 FLRT1 FRMPD3 DDC

3.40e-05184895e0e5a553fb8c0947679634396d20c2ca8455b932
ToppCelldroplet-Lung-3m-Epithelial-airway_epithelial-neuroendocrine_cell-neuroendocrine|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SCN8A ZKSCAN2 FLRT1 FRMPD3 DDC

3.40e-05184895c3b848e1438a84b3fac8a4e40f3db478cc84d970
ToppCelldroplet-Lung-immune-endo-depleted-3m-Epithelial-lung_neuroendocrine_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCN8A ZKSCAN2 FLRT1 FRMPD3 DDC

3.49e-0518589530263c558ee331e0879abcf8b4c2427ff05f9fe7
ToppCelldroplet-Lung-immune-endo-depleted-3m-Epithelial-Neuroendocrine|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCN8A ZKSCAN2 FLRT1 FRMPD3 DDC

3.49e-051858951b000ca11970db8f347eb97ff44605d562aea70a
ToppCellCOVID-19-lung-B_cells|COVID-19 / Disease (COVID-19 only), tissue and cell type

CXCR5 FCRL3 NETO1 ATM WDFY4

3.49e-05185895e8f1ad580f19705b5ca1d7d8867b2125f4891684
ToppCellCOVID-19-kidney-DCT|COVID-19 / Disease (COVID-19 only), tissue and cell type

TRHDE NELL1 NALF1 PKHD1 DSCAML1

3.77e-051888951d56cd409793f05cca20757ab26e91f1a1ee67b5
ToppCellCF-Lymphoid-B_cell|CF / Disease state, Lineage and Cell class

CXCR5 FCRL3 MYCBP2 ATM WDFY4

3.97e-05190895374d8fd63c733178acab07682ed1519693efab45
ToppCellGlobus_pallidus-Neuronal|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

SLC9A5 MYCBP2 TSPOAP1 KCNJ9 SCN8A

3.97e-05190895416de85d8841dac883faa6f5339b2fb461a09e82
ToppCellCOVID-19-kidney-TAL|COVID-19 / Disease (COVID-19 only), tissue and cell type

TRHDE NELL1 SLC9A3 NALF1 PKHD1

4.07e-05191895fe55475ce0666ab5122447a813dc2369e24947b8
ToppCellCF-Lymphoid|CF / Disease state, Lineage and Cell class

CXCR5 FCRL3 MYCBP2 ATM WDFY4

4.27e-0519389511de07d13a7da223990b56fa89ba7fc1c3dd0122
ToppCellAdult-Immune-interstitial_macrophage_(C1Q_positive)-D231|Adult / Lineage, Cell type, age group and donor

LGMN CYSLTR2 ABCA1 MYO9B ARHGAP26

4.38e-05194895800d3d7a9e864d2d6a100a4e4af22f45d5790a8d
ToppCellCOVID-19-Myeloid-Monocyte-derived_macrophages|COVID-19 / group, cell type (main and fine annotations)

LGMN ABCA1 MYO9B ARHGAP26 WDFY4

4.49e-05195895c172c5599379c29123340621a36bfb1fc90c2115
ToppCell(08)_PNEC|World / shred by cell type and Timepoint

NELL1 NALF1 NETO1 GDAP1 DDC

4.60e-051968952ee37155c03cd5009427a4bffe6c80ed2ac6939e
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LGMN ABCA1 MYO9B ARHGAP26 WDFY4

4.71e-051978958af4a1e35ce9fb4ea3d26ab619599efb7eac43a5
ToppCellBronchial-NucSeq-Immune_Lymphocytic-B|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CXCR5 FCRL3 NETO1 MEI1 WDFY4

4.71e-051978950f489d26e4013d1b5a90559856ed2de32a0bb772
ToppCellCOVID-19-Myeloid|COVID-19 / group, cell type (main and fine annotations)

LGMN ABCA1 MYO9B ARHGAP26 WDFY4

4.83e-0519889533f0a919188a67d2a876b52c61a1cec2c9747969
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FOCAD CNTNAP5 NALF1 ARHGAP26 SCN8A

4.83e-051988958ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCellNeuronal|World / cells hierarchy compared to all cells using T-Statistic

FOCAD NALF1 MYCBP2 SCN8A HERC1

5.06e-0520089548d801219bc771d6c7e151dc88ca4c179988de85
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Neuronal-Interneuron|GW19 / Sample Type, Dataset, Time_group, and Cell type.

TRHDE NELL1 KCNJ9 FLRT1

1.02e-04121894b2d571f571133c281d72584fe925cebbd2317829
ToppCellPBMC-Mild-Lymphocyte-B-B_cell-B_intermediate-B_activate-7|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CXCR5 FCRL3 FLRT1 WDFY4

1.30e-0412989458790c6eaa597b8e8209a0fbc970e9cffa10bca5
ToppCellControl-B_activate-7|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

FBXW10B DGLUCY SCN8A TAS2R19

1.34e-04130894d3343c19d61928f18e7d707eda5dec6e0fd2a9a2
ToppCellCOVID-19-kidney-Epithelial_(EC)|COVID-19 / Disease (COVID-19 only), tissue and cell type

CNTNAP5 PKHD1 CNGA2 RYR3

1.47e-04133894a8abb6b54862123961ae6defbf251ee6e9575258
ToppCellThalamus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Slc17a6-Rora-Excitatory_Neuron.Slc17a6.Rora.C1ql2_(Anterodorsal_thalamic_nucleus)|Thalamus / BrainAtlas - Mouse McCarroll V32

ROS1 MEI1 CNGA2

1.73e-04548938a8abf565ea657bf16059c51a63534ede3d7ac12
ToppCellNS-critical-d_07-13-Epithelial-unknown_epithelial|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SLC9A3 HTR1D LAMA5 MAPK8IP3

1.84e-0414189433ad925ff7be3c682741a6328216a89f9d4033e9
ToppCellfacs-Trachea-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l20-23|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SLC9A5 NALF1 ROS1 FAM135B

1.99e-04144894e9d62f202f0fa8747961036ef0eafed91fe8a42f
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CNTNAP5 PKHD1 ROS1 CPS1

2.04e-0414589496712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TMEM221 MCM3 MCM4 RRM1

2.10e-041468942d907e50206c4762a8baa741363bc7f0a04bd84e
ToppCellfacs-Heart-RV-18m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCR2 M1AP TSPOAP1 DENND4B

2.51e-04153894af0ae08ff35f8210268457e5e15bcbe5d1f46d67
ToppCellfacs-Heart-RV-18m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCR2 M1AP TSPOAP1 DENND4B

2.51e-04153894984a2d847f4376183fdbab7ebc77c1bf7d448f44
ToppCellHippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-C1ql1-Inhibitory_Neuron.Gad1Gad2_Pvalb.C1ql1_(Interneuron,_Chandelier)|Hippocampus / BrainAtlas - Mouse McCarroll V32

SLC9A3 HTR1D CPS1

2.60e-046289313d05f73bc15fcfcf2aaa82b74b76753d4abc0ca
ToppCellHippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-C1ql1|Hippocampus / BrainAtlas - Mouse McCarroll V32

SLC9A3 HTR1D CPS1

2.60e-04628937372aff17fc18bd4fee0655254796e60f6b25d24
ToppCellStriatum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb-Inhibitory_Neuron.Gad1Gad2_Pvalb.Pvalb-Megf11_(Fast-spiking_interneuron,_Pvalb+)|Striatum / BrainAtlas - Mouse McCarroll V32

CXCR5 FRMPD3 CPS1

2.60e-04628934a2ef605ed5368f7761199fa1fdf3c2da447fc2e
ToppCellStriatum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb-Inhibitory_Neuron.Gad1Gad2_Pvalb.Pvalb-Megf11_(Fast-spiking_interneuron,_Pvalb+)-|Striatum / BrainAtlas - Mouse McCarroll V32

CXCR5 FRMPD3 CPS1

2.60e-04628932bfa6c957ed4bdf5087a7b233b7ba9eb49d2ae19
ToppCellHippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-C1ql1-Inhibitory_Neuron.Gad1Gad2_Pvalb.C1ql1_(Interneuron,_Chandelier)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

SLC9A3 HTR1D CPS1

2.60e-0462893852a5e778f212b63b9216cd7048972eb35f343c8
ToppCellPND03-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCR2 DENND4B MCM3 MCM4

2.77e-04157894eea53cf8d8a607264e1ee00b7a97c94bcf2ac80d
ToppCellE18.5-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCR2 MCM3 MCM4 WDFY4

2.83e-04158894f61ebe3a316e4259387cd9da83707f15e6473cae
ToppCellSevere-CD8+_T|World / Disease group and Cell class

FCRL3 HORMAD1 DSCAML1

2.86e-04648933e7ede6ec5d8b9c4fc6f3aa8fda91fd9b763ef18
ToppCellE16.5-Immune-Immune_Myeloid-Monocytic-Macrophage-AM|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCR2 TSPOAP1 MYO9B WDFY4

2.90e-041598940c2437da5443fc3aff66f8ef311f02aa434a1fb0
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRHDE NELL1 SLC9A3 MCM4

2.90e-04159894c186bf05c61fac348cf41973827cced83fafd58a
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CNTNAP5 PKHD1 ROS1 CPS1

3.12e-04162894bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell10x5'-bone_marrow-Lymphocytic_B-ABC_aged-B_memory|bone_marrow / Manually curated celltypes from each tissue

CXCR5 SLC9A5 FCRL3 WDFY4

3.26e-04164894746833f74095c0f25ce76baf1069f1848c231933
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRHDE PKHD1 DSCAML1 RYR3

3.26e-041648941cb5fbd7050650047ad6f2ca792118e98d58d22b
ToppCellE18.5-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCR2 MYCBP2 RRM1 WDFY4

3.34e-041658941dcd6b8aa192baeaa1f7bb334843edab6049b96f
ToppCellPND01-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_prolif|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCR2 M1AP MCM3 RRM1

3.34e-04165894ba68090d79e2243af2bdee0c27a32e65f540f8ac
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Stem_cells-neuroepithelial-like_cells|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

CYSLTR2 TMEM221 GOLPH3L KCNJ9

3.50e-04167894e488d9c7cf4355959e3833de3bd496c13fc11b1b
ToppCellE16.5-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCR2 URB1 PPP6R1 WDFY4

3.66e-04169894305cedbd97059029d7d2a248a8a4b6cfe281aa54
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TRHDE CNTNAP5 HTR1F ROS1

3.74e-041708943174ea9cf93892a8b41de10fd4ff6f06bb41502d
ToppCellfacs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l6-17|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NALF1 GDAP1 ZKSCAN2 DDC

3.74e-04170894941d637cf76918ee4b0a1833abd1a42593cb8b1a
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.5.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCA1 MYO9B DENND4B HORMAD1

3.82e-041718945e93c76ee60f9d0590ebb140812653a5e1369417
ToppCellmetastatic_Brain-Fibroblasts-Undetermined|Fibroblasts / Location, Cell class and cell subclass

TSPOAP1 MCM4 HORMAD1 CNOT1

3.91e-04172894c3822ff7329c3ac38c68c5c38cd67c390682e2a6
ToppCellmetastatic_Lymph_Node-Myeloid_cells-Microglia/Mac|metastatic_Lymph_Node / Location, Cell class and cell subclass

SLC26A8 ABCA1 MAP2K3 DNAH1

3.91e-04172894f673a2e697b46e7cfa4186cb3fb2b98e3c83703e
ToppCellfacs-Aorta-Heart-3m-Myeloid|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCR2 CCNDBP1 DENND4B WDFY4

4.00e-04173894513b4d31bcfb269556c6b4cc389865fb12e52c4f
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TRHDE CNTNAP5 ROS1 RYR3

4.08e-04174894ae363ce736fc8af439f3ad594d7bc2e344db80d4
ToppCell18-Distal-RBC-RBC|Distal / Age, Tissue, Lineage and Cell class

CCNDBP1 MAP2K3 WDFY4 RYR3

4.17e-041758947130b816e0c02309c161d8e9ad7cb4bc2469e251
ToppCell18-Distal-RBC|Distal / Age, Tissue, Lineage and Cell class

CCNDBP1 MAP2K3 WDFY4 RYR3

4.17e-04175894cc476b4244442418b8f21721a82a36209b556b36
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRHDE ARHGAP26 PKHD1 DSCAML1

4.26e-04176894327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCellControl-B_cells|Control / group, cell type (main and fine annotations)

FCRL3 ATM MEI1 WDFY4

4.26e-041768949125caa27bf790f6b1b960a86c09b4bcb1b58641
ToppCellControl-B_cells-B_cells|Control / group, cell type (main and fine annotations)

FCRL3 NETO1 ATM WDFY4

4.26e-04176894d2c353783bd78dc24f28e00d917b88d8294fb5df
ToppCellCOVID-19-lung-B_cells|lung / Disease (COVID-19 only), tissue and cell type

CXCR5 FCRL3 NETO1 WDFY4

4.36e-04177894f54691e5558091c1734ab15153a10bff15ed171e
ToppCellControl-Myeloid-MoAM2,_CCL18|Myeloid / Condition, Lineage and Cell class

LGMN ABCA1 PARVA MEI1

4.36e-04177894470f54fe2b21c7350ea471e02039461a3808f700
ToppCellCOVID-19_Moderate-B_intermediate|COVID-19_Moderate / disease group, cell group and cell class

CXCR5 FCRL3 NETO1 WDFY4

4.36e-0417789468e3d12a0c048a2d0f1b9680c7338a35855bba30
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma|TCGA-Brain / Sample_Type by Project: Shred V9

TSPOAP1 FLRT1 HERC1 DSCAML1

4.36e-04177894e8ab340b20cd41554c3841fe980e078e878af35f
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Myeloid-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCR2 DGLUCY DENND4B WDFY4

4.45e-04178894ee674e379ee57e40eb2560ff5ed4c13d8db7ed9d
ToppCell3'-Adult-SmallIntestine-Hematopoietic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CXCR5 CCR2 MYCBP2 WDFY4

4.45e-04178894da1695a936dbe3ca9ee3fb28ceb60511c47b35f8
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Myeloid|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCR2 DGLUCY DENND4B WDFY4

4.45e-041788946c45bf197d6c1be0ef7d3a644c0062acf1e24e4d
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Myeloid-macrophage|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCR2 DGLUCY DENND4B WDFY4

4.45e-04178894cd85dcefe94ee742db64b63e105e13532321894a
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TRHDE ARHGAP26 PKHD1 DSCAML1

4.45e-04178894c20f050344a2e120e685e2a7fe36c6dfc1dc37b6
ToppCell10x_3'_v3-blood_(10x_3'_v3)-myeloid-myeloid_granulocytic-granulocyte|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

LGMN MCM4 WDFY4 ZUP1

4.54e-04179894140dd7dbac48f5f07279f31bf971d7fbd41fa18b
ToppCellLeuk-UTI-Lymphocyte-B-B_intermediate|Leuk-UTI / Disease, Lineage and Cell Type

CXCR5 FCRL3 NETO1 DSCAML1

4.54e-0417989401933f6fa94d7032ed403a6cae6985cafa820043
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRHDE SLC9A3 PKHD1 DSCAML1

4.74e-041818949d782ba5cf5a172cb4f447763fc50e5b13ef7dd9
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRHDE ARHGAP26 PKHD1 DSCAML1

4.74e-041818946956ecd6264f7469a25e555673bce4eb97d28f7a
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Neuronal-medium_spiny_neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HTR1F HIPK4 NETO1 RYR3

4.84e-04182894d41ff834b8fc1d0e23cac7ae261de5f72874e462
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRHDE ARHGAP26 PKHD1 DSCAML1

4.84e-041828945e1b316599436740f1b30875f0ebd33c3edfb2b6
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRHDE SLC9A3 PKHD1 DSCAML1

4.84e-04182894eb138aa1dca9373f1586600f258df06dcf56d81f
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Neuronal-SPN_Neuron_STR|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HTR1F HIPK4 NETO1 RYR3

4.84e-041828946cde859edfe7607bd7ada89d20258413d06f4207
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_B-B_cell-B_c04-SOX5-TNFRSF1B|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

LGMN FCRL3 NETO1 WDFY4

4.84e-041828949c120ddd109103ef6fac9c32b84d16a7624d0580
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRHDE ARHGAP26 PKHD1 DSCAML1

4.94e-04183894738e94b50c4c08c727d4eed0708dda08aa6891b4
ToppCell10x5'-GI_small-bowel-Lymphocytic_B-Naive_B_cells|GI_small-bowel / Manually curated celltypes from each tissue

CXCR5 FCRL3 NETO1 WDFY4

4.94e-04183894be294d22b91dbcf1e8d22e6a31c39b5caaad4751
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-Proliferating_Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NETO1 MCM3 MCM4 RRM1

4.94e-0418389442dc31d587fbb9724b2f0be5ee8ed77233f67b86
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-4|TCGA-Pancreas / Sample_Type by Project: Shred V9

CCR2 ABCA1 HTR1F MYCBP2

5.04e-0418489467164bb6bcae7322cb89b585c7aa10bce35b0ecd
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRHDE FBXW10 TSPOAP1 DNAH1

5.04e-04184894264e14aa1859cfc0ed5fb40e97ea189aed9ef4a5
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRHDE FBXW10 TSPOAP1 DNAH1

5.04e-04184894d7eccbd21c480d907fdc8eff2bf5ae22ae452221
ToppCellCOVID-19_Severe-gd_T|COVID-19_Severe / Disease condition and Cell class

FCRL3 TSPOAP1 MYO9B ARHGAP26

5.04e-04184894791f1bcb954aadc63d4117c400537d036f68734d
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Epithelial-neuroepithelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRHDE FBXW10 TSPOAP1 DNAH1

5.04e-0418489422010cfe0428ebfa40952cc1a1a12ad3d25b35c9
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_B|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CXCR5 FCRL3 MEI1 WDFY4

5.04e-04184894f81209e6bc01a0140f4487aa8b22eb02fbf0c39c
Diseasenephrolithiasis (implicated_via_orthology)

SLC9A3 SLC9A5

8.54e-055872DOID:585 (implicated_via_orthology)
DiseaseGastric Adenocarcinoma

PRKD2 ROS1 ATM

3.21e-0445873C0278701
DiseaseCharcot-Marie-Tooth disease (is_implicated_in)

SLC12A6 GDAP1

5.56e-0412872DOID:10595 (is_implicated_in)
DiseasePROSTATE CANCER, HEREDITARY, 1

MYO9B DENND4B ATM

7.50e-0460873C4722327
Diseasedisease progression measurement

SLC29A3 HERC1 RYR3

7.87e-0461873EFO_0008336
DiseaseProstate cancer, familial

MYO9B DENND4B ATM

1.13e-0369873C2931456
Diseaseurate measurement

PRKD2 ABCA1 GOLPH3L PKHD1 ZKSCAN2 FLRT1 CPS1 FGF19 DNAH1

1.29e-03895879EFO_0004531
Diseasecortical surface area measurement

FOCAD PRKD2 NELL1 HTR1D NALF1 MYCBP2 MYO9B PKHD1 CPS1 MED23 COPS7A

1.98e-0313458711EFO_0010736
DiseaseImmunologic Deficiency Syndromes

ATM EPG5

2.09e-0323872C0021051
Diseaserheumatoid arthritis

TRHDE CXCR5 CCR2 FCRL3 ARHGAP26 WDFY4

2.47e-03462876EFO_0000685
Diseaseantioxidant measurement

NALF1 C16orf96

2.88e-0327872EFO_0005119
DiseaseL-arginine measurement

CPS1 MED23

2.88e-0327872EFO_0006524
Diseaseunipolar depression

CXCR5 NELL1 CNTNAP5 NALF1 KCNJ9 PKHD1 MEI1 MAP2K3 FGF19 FAM135B

2.89e-0312068710EFO_0003761

Protein segments in the cluster

PeptideGeneStartEntry
VHKRLVLAFAVSLVA

TRHDE

36

Q9UKU6
SRHLRTVVHVLDKIL

EPG5

1051

Q9HCE0
HIVIFLDTLARLKAV

CXCR5

276

P32302
LRHLSVVTLAAKVKC

COPS7A

96

Q9UBW8
NSLVIAAIIVTRKLH

HTR1F

41

P30939
IAVSSNRKIHLLDII

FBXW10

426

Q5XX13
LTIDVSAISNLIRKH

ABCA1

1176

O95477
VHTGLKLERALLVTA

CAP1

76

Q01518
KSLISVIHLITAARN

CDIPT

186

O14735
ATLVALLAARTKVIH

DDC

151

P20711
SVLHIVASLIILHLS

NETO1

6

Q8TDF5
RLVVLKQLAHSVVLA

TSPOAP1

796

O95153
RSSHIVEASIRAKLI

KCNJ9

196

Q92806
IAVSSNRKIHLLDII

FBXW10B

426

O95170
SLIRLAEAHAKVRLS

MCM4

736

P33991
HSLTLLVKAVATREL

M1AP

391

Q8TC57
SVLSLVHVKGRVLVA

MAPK8IP3

1001

Q9UPT6
LTALARLKELAIIHA

HIPK4

121

Q8NE63
LIHDLLTIFVSAKLA

EIF3M

236

Q7L2H7
DTVSRFVLAALLKHT

HERC1

1261

Q15751
LIHALSAVESAVLLA

OR51D1

116

Q8NGF3
LADVSLAVTLHRLKF

GDAP1

246

Q8TB36
AHSLLEIKAVALRTV

FGF19

76

O95750
RVIKLAHAKSSVALA

MED23

546

Q9ULK4
AATARAVHILTKLTE

NRDE2

841

Q9H7Z3
TKFLITQILVALRHL

PRKD2

651

Q9BZL6
TLGHAKTLLAAIRAV

LAMA5

2271

O15230
KVALSVSASHLLLHV

NELL1

151

Q92832
VDTAHKVLISLRTFL

MEI1

856

Q5TIA1
ALVHLLSRKKVIAFT

OR2D2

81

Q9H210
RTLETLIRLATAHAK

MCM3

616

P25205
RAVLSALIVIEVHAK

DNAH1

1486

Q9P2D7
HILAALTIFLKTLAV

ATM

231

Q13315
LTKHLVELSILARTF

ATM

2251

Q13315
IRLLSVKAQTAHIVL

CPS1

36

P31327
LHRLKTTAAIAAAAA

C16orf96

561

A6NNT2
HLTVRINSAKLVSVL

CCNDBP1

301

O95273
LIHTNGTLLLRAVKA

DSCAML1

1341

Q8TD84
IRSAKEFIVLTVLHT

FRMPD3

116

Q5JV73
RTLALLVLAHSSDVL

GOLPH3L

221

Q9H4A5
NAFVLTTILLTRKLH

HTR1D

56

P28221
AIVHAVFALKARTVT

CCR2

141

P41597
VALIKDHTLVNSLIR

DENND5A

1251

Q6IQ26
VLSILVLAAAAALLH

FCRL3

581

Q96P31
ASLSLALLESVLRHV

DENND4B

1386

O75064
STEHQSLVLVKRLLA

HORMAD1

21

Q86X24
LSVISVTVHAALVAL

FAM135B

161

Q49AJ0
LAIHVKALTADSIRI

FLRT1

411

Q9NZU1
LKASLSLSHARSVLI

DGLUCY

321

Q7Z3D6
RVTTAAHLALLVAKN

SLC12A6

881

Q9UHW9
HILAIATKDVRIFTL

SEH1L

236

Q96EE3
LKAALRHATVAPVTV

CNTNAP5

1176

Q8WYK1
LLALSSLAVVVSRHE

FOCAD

961

Q5VW36
VSIVRALEHLHSKLS

MAP2K3

171

P46734
VHRVLKLAHTDIFIL

OR4D10

181

Q8NGI6
VRSLALKLLAFHLTS

RTTN

771

Q86VV8
IKLRNAIHLSSLTVT

TAS2R19

166

P59542
IKLRNAIHLSSLTVT

TAS2R33

166

P0DSN6
VHIRVLASLTVILAI

SLC29A3

131

Q9BZD2
LHQLTVLASVLLVAR

TCP11X2

231

Q5H9J9
LSVHDAVLFALSRKV

SLC26A8

786

Q96RN1
LLSLVTRFTKHVRII

SLC9A3

271

P48764
AAVVLSLARSSLHAV

ARHGAP26

711

Q9UNA1
TSHVAAVLASLLVLL

SIGIRR

116

Q6IA17
VASLAKIVFHLSRKV

SLC9A5

56

Q14940
VVRASKDLLHRALAV

MYCBP2

1916

O75592
HILKATVALLSRSIT

PKHD1

2126

P08F94
SVHAKSLVAILHLLV

PARVA

181

Q9NVD7
VRHTALSLISVILKR

URB1

451

O60287
LRAEIAINVHLSTLK

CNGA2

436

Q16280
DRLHKALVITLALAA

CYSLTR2

281

Q9NS75
LDAFVRLIALLVKHS

CNOT1

1936

A5YKK6
KAFSRITSLIVHVRI

ZNF260

311

Q3ZCT1
ILAARIAVSNLHKET

RRM1

76

P23921
TLRALAIIHTIISLV

RYR3

4476

Q15413
VTALAVSRNHTKLLV

WDFY4

3156

Q6ZS81
KRLIDLHTNVATAVL

SCFD1

396

Q8WVM8
IRRIAIKILIHSVFS

SCN8A

121

Q9UQD0
AIVSQVKALRSRHIL

ROS1

1416

P08922
LGNTRLHVVKLLASA

PPP6R1

351

Q9UPN7
ILLTSLRVKCHIVDF

ZUP1

431

Q96AP4
TLVLVAVLTHTLLRA

TMEM221

161

A6NGB7
RLKRIAISAKEHISL

ZKSCAN2

446

Q63HK3
RAALLHKTIQLAAEL

SH2D3C

661

Q8N5H7
HSLIKVLRLVCLQSV

VPS33A

401

Q96AX1
RLVATVLLSVVVLLH

YIPF2

256

Q9BWQ6
ITVLSRLFRTVISKH

TERB1

146

Q8NA31
ALLLSVSHLVLVTRN

TMEM98

161

Q9Y2Y6
ARHLIEKSVRKIVSL

LGMN

341

Q99538
VLVLILLHTVLTASA

NALF1

421

B1AL88
SLERLIFHLVKVALL

MYO9B

1821

Q13459