| Category | Name | IntersectionWithQuery | PValue | GenesInTerm | GenesInQuery | GenesInTermInQuery | ID |
|---|---|---|---|---|---|---|---|
| GeneOntologyMolecularFunction | structural constituent of postsynaptic actin cytoskeleton | 9.91e-06 | 11 | 9 | 2 | GO:0098973 | |
| GeneOntologyMolecularFunction | 2 iron, 2 sulfur cluster binding | 7.29e-05 | 29 | 9 | 2 | GO:0051537 | |
| GeneOntologyMolecularFunction | structural constituent of postsynapse | 8.89e-05 | 32 | 9 | 2 | GO:0099186 | |
| GeneOntologyMolecularFunction | structural constituent of synapse | 1.54e-04 | 42 | 9 | 2 | GO:0098918 | |
| GeneOntologyMolecularFunction | iron-sulfur cluster binding | 5.33e-04 | 78 | 9 | 2 | GO:0051536 | |
| GeneOntologyMolecularFunction | metal cluster binding | 6.03e-04 | 83 | 9 | 2 | GO:0051540 | |
| GeneOntologyMolecularFunction | structural constituent of cytoskeleton | 1.47e-03 | 130 | 9 | 2 | GO:0005200 | |
| GeneOntologyBiologicalProcess | postsynaptic actin cytoskeleton organization | 7.82e-05 | 31 | 9 | 2 | GO:0098974 | |
| GeneOntologyBiologicalProcess | postsynaptic cytoskeleton organization | 1.00e-04 | 35 | 9 | 2 | GO:0099188 | |
| GeneOntologyCellularComponent | H4/H2A histone acetyltransferase complex | 6.32e-05 | 32 | 8 | 2 | GO:0043189 | |
| GeneOntologyCellularComponent | NuA4 histone acetyltransferase complex | 6.32e-05 | 32 | 8 | 2 | GO:0035267 | |
| GeneOntologyCellularComponent | H4 histone acetyltransferase complex | 1.26e-04 | 45 | 8 | 2 | GO:1902562 | |
| GeneOntologyCellularComponent | histone acetyltransferase complex | 5.50e-04 | 94 | 8 | 2 | GO:0000123 | |
| GeneOntologyCellularComponent | protein acetyltransferase complex | 6.73e-04 | 104 | 8 | 2 | GO:0031248 | |
| GeneOntologyCellularComponent | acetyltransferase complex | 7.39e-04 | 109 | 8 | 2 | GO:1902493 | |
| GeneOntologyCellularComponent | blood microparticle | 1.28e-03 | 144 | 8 | 2 | GO:0072562 | |
| GeneOntologyCellularComponent | actin filament | 1.32e-03 | 146 | 8 | 2 | GO:0005884 | |
| GeneOntologyCellularComponent | mitochondrial outer membrane | 3.54e-03 | 241 | 8 | 2 | GO:0005741 | |
| GeneOntologyCellularComponent | organelle outer membrane | 4.71e-03 | 279 | 8 | 2 | GO:0031968 | |
| GeneOntologyCellularComponent | outer membrane | 4.78e-03 | 281 | 8 | 2 | GO:0019867 | |
| GeneOntologyCellularComponent | chromatin | 1.51e-02 | 1480 | 8 | 3 | GO:0000785 | |
| GeneOntologyCellularComponent | actin cytoskeleton | 1.90e-02 | 576 | 8 | 2 | GO:0015629 | |
| MousePheno | decreased circulating triglyceride level | 7.31e-05 | 275 | 5 | 3 | MP:0002644 | |
| MousePheno | decreased triglyceride level | 1.47e-04 | 348 | 5 | 3 | MP:0005318 | |
| MousePheno | abnormal respiratory electron transport chain | 4.60e-04 | 96 | 5 | 2 | MP:0010955 | |
| MousePheno | abnormal circulating triglyceride level | 4.73e-04 | 516 | 5 | 3 | MP:0011969 | |
| MousePheno | abnormal triglyceride level | 8.87e-04 | 639 | 5 | 3 | MP:0000187 | |
| MousePheno | abnormal cellular respiration | 1.13e-03 | 151 | 5 | 2 | MP:0010954 | |
| MousePheno | decreased lipid level | 1.29e-03 | 727 | 5 | 3 | MP:0014461 | |
| Domain | FeS-contain_mitoNEET_N | 2.06e-07 | 2 | 9 | 2 | IPR019610 | |
| Domain | MitoNEET_N | 2.06e-07 | 2 | 9 | 2 | PF10660 | |
| Domain | zf-CDGSH | 6.19e-07 | 3 | 9 | 2 | PF09360 | |
| Domain | FeS-contain_CDGSH-typ | 6.19e-07 | 3 | 9 | 2 | IPR018967 | |
| Domain | ZnF_CDGSH | 6.19e-07 | 3 | 9 | 2 | SM00704 | |
| Domain | Actin_CS | 2.47e-05 | 16 | 9 | 2 | IPR004001 | |
| Domain | ACTINS_2 | 2.80e-05 | 17 | 9 | 2 | PS00432 | |
| Domain | Actin/actin-like_CS | 3.15e-05 | 18 | 9 | 2 | IPR020902 | |
| Domain | ACTINS_ACT_LIKE | 3.51e-05 | 19 | 9 | 2 | PS01132 | |
| Domain | ACTIN | 9.53e-05 | 31 | 9 | 2 | SM00268 | |
| Domain | Actin | 9.53e-05 | 31 | 9 | 2 | IPR004000 | |
| Domain | Actin | 9.53e-05 | 31 | 9 | 2 | PF00022 | |
| Domain | Ank_2 | 4.50e-03 | 215 | 9 | 2 | PF12796 | |
| Domain | Ank | 5.05e-03 | 228 | 9 | 2 | PF00023 | |
| Domain | - | 5.94e-03 | 248 | 9 | 2 | 1.25.40.20 | |
| Domain | ANK | 6.09e-03 | 251 | 9 | 2 | SM00248 | |
| Domain | ANK_REPEAT | 6.18e-03 | 253 | 9 | 2 | PS50088 | |
| Domain | Ankyrin_rpt-contain_dom | 6.23e-03 | 254 | 9 | 2 | IPR020683 | |
| Domain | ANK_REP_REGION | 6.23e-03 | 254 | 9 | 2 | PS50297 | |
| Domain | Ankyrin_rpt | 6.61e-03 | 262 | 9 | 2 | IPR002110 | |
| Pathway | KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_OPTN_TO_PINK_PARKIN_MEDIATED_AUTOPHAGOSOME_FORMATION | 7.60e-06 | 9 | 7 | 2 | M47743 | |
| Pathway | KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_P62_TO_PINK_PARKIN_MEDIATED_AUTOPHAGOSOME_FORMATION | 1.64e-05 | 13 | 7 | 2 | M47744 | |
| Pathway | KEGG_MEDICUS_REFERENCE_PINK_PARKIN_MEDIATED_AUTOPHAGOSOME_FORMATION | 2.86e-05 | 17 | 7 | 2 | M47742 | |
| Pubmed | 5.95e-08 | 2 | 9 | 2 | 23959881 | ||
| Pubmed | A primate-specific POTE-actin fusion protein plays a role in apoptosis. | 5.95e-08 | 2 | 9 | 2 | 19669888 | |
| Pubmed | Evolution and expression of chimeric POTE-actin genes in the human genome. | 1.79e-07 | 3 | 9 | 2 | 17101985 | |
| Pubmed | The outer mitochondrial membrane protein mitoNEET contains a novel redox-active 2Fe-2S cluster. | 1.79e-07 | 3 | 9 | 2 | 17584744 | |
| Pubmed | 4.64e-06 | 13 | 9 | 2 | 17376863 | ||
| Pubmed | Identification of a novel actin isoform in hepatocellular carcinoma. | 6.24e-06 | 15 | 9 | 2 | 16824795 | |
| Pubmed | 2.38e-04 | 504 | 9 | 3 | 34432599 | ||
| Cytoband | 2q21.1 | 5.61e-05 | 58 | 9 | 2 | 2q21.1 | |
| Cytoband | Ensembl 112 genes in cytogenetic band chr2q21 | 3.81e-04 | 151 | 9 | 2 | chr2q21 | |
| GeneFamily | CDGSH iron sulfur domain containing | 3.85e-07 | 3 | 7 | 2 | 481 | |
| GeneFamily | Ankyrin repeat domain containing|POTE ankyrin domain containing | 1.00e-05 | 13 | 7 | 2 | 685 | |
| GeneFamily | Ankyrin repeat domain containing | 3.58e-03 | 242 | 7 | 2 | 403 | |
| ToppCell | Smart-seq2-blood_(Smart-seq2)-hematologic|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type | 5.64e-06 | 185 | 9 | 3 | 9f1a790680caaf9c1ec35db5e4b7641497401179 | |
| ToppCell | TCGA-Brain-Primary_Tumor-Glioblastoma-Primary_GBM-11|TCGA-Brain / Sample_Type by Project: Shred V9 | 6.90e-05 | 63 | 9 | 2 | d7dc1356a60cb527fe668328d5375f352239d911 | |
| ToppCell | TCGA-Brain-Primary_Tumor-Glioblastoma|TCGA-Brain / Sample_Type by Project: Shred V9 | 7.35e-05 | 65 | 9 | 2 | 3592efe68696dd5b806183c8bcd4957c1cd8e045 | |
| ToppCell | TCGA-Brain-Primary_Tumor-Glioblastoma-Primary_GBM|TCGA-Brain / Sample_Type by Project: Shred V9 | 7.35e-05 | 65 | 9 | 2 | c53b6e1e454b7c34cac07b287ffd9e8e64fa79c8 | |
| ToppCell | TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Lobular_Carcinoma-9|TCGA-Breast / Sample_Type by Project: Shred V9 | 1.41e-04 | 90 | 9 | 2 | 96e836c7a1df279ac812b7c3aa75e6b81b614244 | |
| ToppCell | TCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Malignant_Peripheral_Nerve_Sheath_Tumors-3|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9 | 2.00e-04 | 107 | 9 | 2 | c6c6ace2e578e48f135b53e50ece540350dc640a | |
| ToppCell | 390C-Lymphocytic-NK_cells-NK_cell_B0|NK_cells / Donor, Lineage, Cell class and subclass (all cells) | 4.73e-04 | 165 | 9 | 2 | ebd668e87e5961a124d1d6fc25d1f03e4af05cd4 | |
| ToppCell | Adult-Endothelial-endothelial_cell_of_artery-D231|Adult / Lineage, Cell type, age group and donor | 4.90e-04 | 168 | 9 | 2 | aca34c51758c65925ad24110294a72b2dea6db72 | |
| ToppCell | 5'-Adult-Appendix-Hematopoietic-T_cells-Treg|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract | 5.14e-04 | 172 | 9 | 2 | c74c1d47b133eb5d0f762a06e421252a76b4672b | |
| ToppCell | 5'-Adult-LargeIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract | 5.32e-04 | 175 | 9 | 2 | 182e45f5c02214d6b9f317ff5dc43af8b42de978 | |
| ToppCell | Smart-seq2-blood_(Smart-seq2)-hematologic-thrombocytic-platelet|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type | 5.63e-04 | 180 | 9 | 2 | beb4d777e0c5fa0a59672dbc3dbb7732498605ff | |
| ToppCell | Smart-seq2-blood_(Smart-seq2)-hematologic-thrombocytic|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type | 5.63e-04 | 180 | 9 | 2 | fb3d549c2a69b2157a486786ddd775ca16699ed0 | |
| ToppCell | 5'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract | 5.69e-04 | 181 | 9 | 2 | 9bfd93cf053beaee806cacdffd7abef02f94aec6 | |
| ToppCell | 3'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract | 5.75e-04 | 182 | 9 | 2 | 0346f81bbb1f309f3e9d063b20547d548d09472c | |
| ToppCell | 3'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract | 5.94e-04 | 185 | 9 | 2 | 602536a3308a848f106adcb0a83530997440c8f4 | |
| ToppCell | 3'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract | 6.07e-04 | 187 | 9 | 2 | 0ef82111b9049cc7ee78d64d240e1f10ab14d6b6 | |
| ToppCell | 3'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract | 6.07e-04 | 187 | 9 | 2 | 25efb82afe863a853ecdd781ad89026c993aaa67 | |
| ToppCell | 3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5 | 6.26e-04 | 190 | 9 | 2 | d0297d678498e346e56cf95fe9e3db7d3ad3b837 | |
| ToppCell | renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group | 6.46e-04 | 193 | 9 | 2 | 2e72309607902dabe3218888b22a77fe941f3570 | |
| ToppCell | metastatic_Brain-B_lymphocytes-MALT_B_cells|B_lymphocytes / Location, Cell class and cell subclass | 6.46e-04 | 193 | 9 | 2 | d05535eaabb6b4069b72b23d852888d4191407fd | |
| ToppCell | ASK440-Endothelial-Endothelium|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq | 6.59e-04 | 195 | 9 | 2 | 304f0dc91bb57e98b0ca31d6bfb3ff9364e4da56 | |
| ToppCell | 5'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract | 6.66e-04 | 196 | 9 | 2 | ae46d4b00be92e64e46252dcc156161b171eded4 | |
| ToppCell | 3'-GW_trimst-1.5-LargeIntestine-Endothelial|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract | 6.66e-04 | 196 | 9 | 2 | 629236f95c838a473b5964a49b7c1b7ad863ea12 | |
| ToppCell | droplet-Kidney-nan-3m|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 6.66e-04 | 196 | 9 | 2 | b880c9665d42c76ea1971d4e49d7ecf72fcfafb6 | |
| ToppCell | ILEUM-inflamed-(7)_Endothelial_cell-(7)_CD36+_endothelial_cells|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2) | 6.73e-04 | 197 | 9 | 2 | 66339b5aae3952f5c484c9dcb0cfb4fbd828d4cb | |
| ToppCell | 3'-GW_trimst-1-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract | 6.73e-04 | 197 | 9 | 2 | 98e34e8612f111bb667a574de1faaa785d318ca4 | |
| ToppCell | 343B-Fibroblasts-Fibroblast-F-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells) | 6.87e-04 | 199 | 9 | 2 | 4338bf6cafc26c5d6497955d91914f84bacfacfa | |
| ToppCell | BAL-Severe-cDC_9|Severe / Compartment, Disease Groups and Clusters | 6.87e-04 | 199 | 9 | 2 | 9bf63b6005addc926b77417f426b89c573bf40d9 | |
| ToppCell | Megakaryocytic-erythropoietic-Erythro-cells-Polychromatic_Erythroblast|Erythro-cells / Lineage, cell class and subclass | 6.87e-04 | 199 | 9 | 2 | 304681a6510c05203aab360ed72bfe929d8e4ac3 | |
| ToppCell | 3'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract | 6.87e-04 | 199 | 9 | 2 | b15304d3d3f6c254969b54a61bee3d9f368840b2 | |
| ToppCell | 343B-Fibroblasts-Fibroblast-F|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells) | 6.87e-04 | 199 | 9 | 2 | 08c7e631b2e203dd7dcb75a7f9377d292bc5a0fd | |
| ToppCell | tumor_Lymph_Node_/_Brain-Fibroblasts-Myofibroblasts|Fibroblasts / Location, Cell class and cell subclass | 6.93e-04 | 200 | 9 | 2 | eabb7d4aa92ace7d970bcd3fae2c7cb5400a43b4 | |
| ToppCell | 5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract | 6.93e-04 | 200 | 9 | 2 | 90061284a80d29a4ca6078f578e13d32b8cc80e1 | |
| ToppCell | 5'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract | 6.93e-04 | 200 | 9 | 2 | 9e44da8aaac239ed69d674dcd53800c5eaf397cb | |
| Drug | Dipyrone [5907-38-0]; Down 200; 12uM; MCF7; HT_HG-U133A | 5.00e-05 | 195 | 9 | 3 | 3835_DN | |
| Drug | Ritodrine hydrochloride [23239-51-2]; Down 200; 12.4uM; MCF7; HT_HG-U133A | 5.08e-05 | 196 | 9 | 3 | 5680_DN | |
| Disease | Back pain | 2.38e-04 | 87 | 8 | 2 | HP_0003418 | |
| Disease | Alzheimer disease, polygenic risk score | 1.02e-02 | 586 | 8 | 2 | EFO_0030082, MONDO_0004975 | |
| Disease | aspartate aminotransferase measurement | 2.32e-02 | 904 | 8 | 2 | EFO_0004736 |
| Peptide | Gene | Start | Entry |
|---|---|---|---|
| KWCCRCFPCCRESGK | 26 | A5A3E0 | |
| CDSNPYCKAWAVRKC | 1456 | Q7Z5P9 | |
| RSKMGKWCCRCFPCY | 21 | Q6S8J3 | |
| KWCCRCFPCYRESGK | 26 | Q6S8J3 | |
| GCQPKLCDYRCIWCQ | 146 | P52429 | |
| CRPSKGRKRGFCWCV | 251 | P17936 | |
| YCRCWRSKKFPFCDG | 71 | Q9NZ45 | |
| AAYCRCWRSKTFPAC | 96 | Q8N5K1 | |
| KFCDYCKCWIADNRP | 11 | O75554 | |
| LRCFYCCTGCGKVFW | 826 | Q8N9H8 |