Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	bone sialoprotein binding	ANXA2 ANXA2P2	1.25e-05	2	71	2	GO:0044730
GeneOntologyMolecularFunction	phospholipase A2 inhibitor activity	ANXA2 ANXA2P2	1.24e-04	5	71	2	GO:0019834
GeneOntologyMolecularFunction	damaged DNA binding	ERCC2 ERCC3 POLI NEIL3	2.28e-04	84	71	4	GO:0003684
GeneOntologyBiologicalProcess	multi-pass transmembrane protein insertion into ER membrane	NOMO2 NOMO3 NOMO1	3.37e-06	9	72	3	GO:0160063
GeneOntologyBiologicalProcess	positive regulation of low-density lipoprotein particle receptor binding	ANXA2 ANXA2P2	1.20e-05	2	72	2	GO:1905597
GeneOntologyBiologicalProcess	plasma membrane bounded cell projection assembly	TBC1D9B STON1 FGD1 PIP5K1A TBC1D22B NCK1 FGD5 IFT122 FGD3 CFAP46 DNAH1	1.95e-05	670	72	11	GO:0120031
GeneOntologyBiologicalProcess	endomembrane system organization	UBE2I NOMO2 COG7 ANXA2 ANXA2P2 ATL3 RAB1B EMD NOMO3 FER1L6 NOMO1	2.01e-05	672	72	11	GO:0010256
GeneOntologyBiologicalProcess	cell projection assembly	TBC1D9B STON1 FGD1 PIP5K1A TBC1D22B NCK1 FGD5 IFT122 FGD3 CFAP46 DNAH1	2.39e-05	685	72	11	GO:0030031
GeneOntologyBiologicalProcess	positive regulation of receptor-mediated endocytosis involved in cholesterol transport	ANXA2 ANXA2P2	3.60e-05	3	72	2	GO:1905602
GeneOntologyBiologicalProcess	negative regulation of low-density lipoprotein particle receptor catabolic process	ANXA2 ANXA2P2	3.60e-05	3	72	2	GO:0032804
GeneOntologyBiologicalProcess	positive regulation of low-density lipoprotein particle clearance	ANXA2 ANXA2P2	7.18e-05	4	72	2	GO:1905581
GeneOntologyBiologicalProcess	negative regulation of receptor catabolic process	ANXA2 ANXA2P2	7.18e-05	4	72	2	GO:2000645
GeneOntologyBiologicalProcess	positive regulation of intracellular cholesterol transport	ANXA2 ANXA2P2	7.18e-05	4	72	2	GO:0032385
GeneOntologyBiologicalProcess	positive regulation of intracellular sterol transport	ANXA2 ANXA2P2	7.18e-05	4	72	2	GO:0032382
GeneOntologyBiologicalProcess	positive regulation of plasma membrane repair	ANXA2 ANXA2P2	1.19e-04	5	72	2	GO:1905686
GeneOntologyBiologicalProcess	regulation of low-density lipoprotein particle receptor binding	ANXA2 ANXA2P2	1.19e-04	5	72	2	GO:1905595
GeneOntologyBiologicalProcess	positive regulation of intracellular lipid transport	ANXA2 ANXA2P2	1.19e-04	5	72	2	GO:0032379
GeneOntologyBiologicalProcess	protein insertion into ER membrane	NOMO2 NOMO3 NOMO1	1.71e-04	31	72	3	GO:0045048
GeneOntologyBiologicalProcess	positive regulation of low-density lipoprotein receptor activity	ANXA2 ANXA2P2	1.79e-04	6	72	2	GO:1905599
GeneOntologyBiologicalProcess	negative regulation of nodal signaling pathway	NOMO3 NOMO1	2.50e-04	7	72	2	GO:1900108
GeneOntologyBiologicalProcess	regulation of low-density lipoprotein particle receptor catabolic process	ANXA2 ANXA2P2	2.50e-04	7	72	2	GO:0032803
GeneOntologyBiologicalProcess	low-density lipoprotein particle receptor catabolic process	ANXA2 ANXA2P2	2.50e-04	7	72	2	GO:0032802
GeneOntologyBiologicalProcess	low-density lipoprotein receptor particle metabolic process	ANXA2 ANXA2P2	2.50e-04	7	72	2	GO:0032799
GeneOntologyBiologicalProcess	regulation of receptor-mediated endocytosis involved in cholesterol transport	ANXA2 ANXA2P2	3.32e-04	8	72	2	GO:1905600
GeneOntologyBiologicalProcess	regulation of plasma membrane repair	ANXA2 ANXA2P2	3.32e-04	8	72	2	GO:1905684
GeneOntologyBiologicalProcess	positive regulation of receptor binding	ANXA2 ANXA2P2	3.32e-04	8	72	2	GO:1900122
GeneOntologyBiologicalProcess	transcription elongation by RNA polymerase I	ERCC2 ERCC3	4.26e-04	9	72	2	GO:0006362
GeneOntologyBiologicalProcess	regulation of nodal signaling pathway	NOMO3 NOMO1	4.26e-04	9	72	2	GO:1900107
GeneOntologyBiologicalProcess	actin cytoskeleton organization	CSF1R FGD1 PIP5K1A NCK1 FGD5 ANKRD23 ARPC5 TNXB FGD3 MYO5C	4.56e-04	803	72	10	GO:0030036
GeneOntologyBiologicalProcess	determination of left/right asymmetry in lateral mesoderm	NOMO3 NOMO1	5.31e-04	10	72	2	GO:0003140
GeneOntologyBiologicalProcess	transcription-coupled nucleotide-excision repair	ERCC2 ERCC3	5.31e-04	10	72	2	GO:0006283
GeneOntologyBiologicalProcess	endoplasmic reticulum organization	NOMO2 ATL3 NOMO3 NOMO1	5.37e-04	107	72	4	GO:0007029
GeneOntologyBiologicalProcess	receptor-mediated endocytosis involved in cholesterol transport	ANXA2 ANXA2P2	6.48e-04	11	72	2	GO:0090118
GeneOntologyBiologicalProcess	protein insertion into membrane	NOMO2 NOMO3 NOMO1	7.11e-04	50	72	3	GO:0051205
GeneOntologyBiologicalProcess	positive regulation of lipoprotein particle clearance	ANXA2 ANXA2P2	7.75e-04	12	72	2	GO:0010986
GeneOntologyBiologicalProcess	regulation of intracellular sterol transport	ANXA2 ANXA2P2	7.75e-04	12	72	2	GO:0032380
GeneOntologyBiologicalProcess	regulation of intracellular cholesterol transport	ANXA2 ANXA2P2	7.75e-04	12	72	2	GO:0032383
GeneOntologyBiologicalProcess	UV protection	ERCC2 ERCC3	9.14e-04	13	72	2	GO:0009650
GeneOntologyBiologicalProcess	regulation of intracellular lipid transport	ANXA2 ANXA2P2	9.14e-04	13	72	2	GO:0032377
GeneOntologyCellularComponent	multi-pass translocon complex	NOMO2 NOMO3 NOMO1	3.67e-06	9	75	3	GO:0160064
GeneOntologyCellularComponent	ER membrane insertion complex	NOMO2 NOMO3 NOMO1	1.57e-05	14	75	3	GO:0072379
GeneOntologyCellularComponent	AnxA2-p11 complex	ANXA2 ANXA2P2	3.80e-05	3	75	2	GO:1990665
GeneOntologyCellularComponent	PCSK9-AnxA2 complex	ANXA2 ANXA2P2	3.80e-05	3	75	2	GO:1990667
GeneOntologyCellularComponent	cell leading edge	STON1 ANXA2 ANXA2P2 INSR FGD1 PIP5K1A FGD5 ARPC5 FGD3	7.38e-05	500	75	9	GO:0031252
GeneOntologyCellularComponent	carboxy-terminal domain protein kinase complex	ERCC2 ERCC3 SNW1	8.50e-05	24	75	3	GO:0032806
GeneOntologyCellularComponent	ruffle	ANXA2 ANXA2P2 FGD1 PIP5K1A FGD5 FGD3	9.74e-05	206	75	6	GO:0001726
GeneOntologyCellularComponent	endoplasmic reticulum tubular network	ATL3 EMD KPNB1	1.85e-04	31	75	3	GO:0071782
GeneOntologyCellularComponent	signal peptidase complex	SEC11A SEC11C	1.89e-04	6	75	2	GO:0005787
GeneOntologyCellularComponent	myelin sheath adaxonal region	ANXA2 ANXA2P2	2.64e-04	7	75	2	GO:0035749
GeneOntologyCellularComponent	pinosome	ANXA2 ANXA2P2	6.84e-04	11	75	2	GO:0044352
GeneOntologyCellularComponent	macropinosome	ANXA2 ANXA2P2	6.84e-04	11	75	2	GO:0044354
GeneOntologyCellularComponent	transcription factor TFIIH core complex	ERCC2 ERCC3	8.19e-04	12	75	2	GO:0000439
GeneOntologyCellularComponent	nuclear inner membrane	TMEM120B TMEM120A EMD	1.25e-03	59	75	3	GO:0005637
GeneOntologyCellularComponent	transferase complex, transferring phosphorus-containing groups	ERCC2 ERCC3 SNW1 SOCS5 INSR DNA2	1.29e-03	335	75	6	GO:0061695
GeneOntologyCellularComponent	transcription factor TFIIH holo complex	ERCC2 ERCC3	1.29e-03	15	75	2	GO:0005675
GeneOntologyCellularComponent	lamellipodium	FGD1 PIP5K1A FGD5 ARPC5 FGD3	1.43e-03	230	75	5	GO:0030027
GeneOntologyCellularComponent	Schmidt-Lanterman incisure	ANXA2 ANXA2P2	1.67e-03	17	75	2	GO:0043220
GeneOntologyCellularComponent	transferase complex	ERCC2 ERCC3 SNW1 RNMT UBE2I FBXO42 SOCS5 INSR HADHB DNA2	2.25e-03	963	75	10	GO:1990234
GeneOntologyCellularComponent	serine-type endopeptidase complex	SEC11A SEC11C	2.31e-03	20	75	2	GO:1905370
GeneOntologyCellularComponent	compact myelin	ANXA2 ANXA2P2	2.55e-03	21	75	2	GO:0043218
GeneOntologyCellularComponent	serine-type peptidase complex	SEC11A SEC11C	2.80e-03	22	75	2	GO:1905286
GeneOntologyCellularComponent	protein kinase complex	ERCC2 ERCC3 SNW1 INSR	3.28e-03	170	75	4	GO:1902911
GeneOntologyCellularComponent	nuclear periphery	SNW1 ANXA2 ANXA2P2 EMD	3.35e-03	171	75	4	GO:0034399
Domain	LRRC37AB_C	LRRC37A LRRC37A3 LRRC37A2 LRRC37B	2.40e-10	4	75	4	PF14914
Domain	LRRC37_N	LRRC37A LRRC37A3 LRRC37A2 LRRC37B	2.40e-10	4	75	4	IPR032754
Domain	LRRC37AB_C	LRRC37A LRRC37A3 LRRC37A2 LRRC37B	2.40e-10	4	75	4	IPR029423
Domain	LRRC37	LRRC37A LRRC37A3 LRRC37A2 LRRC37B	2.40e-10	4	75	4	PF15779
Domain	LRRC37A/B-like	LRRC37A LRRC37A3 LRRC37A2 LRRC37B	2.40e-10	4	75	4	IPR015753
Domain	DUF2012	NOMO2 NOMO3 NOMO1	2.48e-07	4	75	3	PF09430
Domain	DUF2012	NOMO2 NOMO3 NOMO1	2.48e-07	4	75	3	IPR019008
Domain	Carb-bd-like_fold	NOMO2 NOMO3 NOMO1	3.43e-06	8	75	3	IPR013784
Domain	Peptidase_S26B	SEC11A SEC11C	1.59e-05	2	75	2	IPR001733
Domain	TMPIT	TMEM120B TMEM120A	1.59e-05	2	75	2	IPR012926
Domain	Pept_S26A_signal_pept_1_Ser-AS	SEC11A SEC11C	1.59e-05	2	75	2	IPR019756
Domain	TMPIT	TMEM120B TMEM120A	1.59e-05	2	75	2	PF07851
Domain	CarboxyPept_regulatory_dom	NOMO2 NOMO3 NOMO1	1.73e-05	13	75	3	IPR014766
Domain	-	NOMO2 NOMO3 NOMO1	1.73e-05	13	75	3	2.60.40.1120
Domain	CarboxyPept-like_regulatory	NOMO2 NOMO3 NOMO1	4.06e-05	17	75	3	IPR008969
Domain	Pept_S26A_signal_pept_1_CS	SEC11A SEC11C	4.76e-05	3	75	2	IPR019758
Domain	SPASE_I_3	SEC11A SEC11C	9.50e-05	4	75	2	PS00761
Domain	Peptidase_S24	SEC11A SEC11C	9.50e-05	4	75	2	PF00717
Domain	-	SEC11A SEC11C	9.50e-05	4	75	2	2.10.109.10
Domain	Peptidase_S24_S26A/B/C	SEC11A SEC11C	9.50e-05	4	75	2	IPR015927
Domain	SPASE_I_1	SEC11A SEC11C	9.50e-05	4	75	2	PS00501
Domain	Peptidase_S24/S26_b-rbn	SEC11A SEC11C	9.50e-05	4	75	2	IPR028360
Domain	Peptidase_S24_S26	SEC11A SEC11C	9.50e-05	4	75	2	IPR019759
Domain	FYVE	FGD1 FGD5 FGD3	2.11e-04	29	75	3	PF01363
Domain	FYVE	FGD1 FGD5 FGD3	2.11e-04	29	75	3	SM00064
Domain	Znf_FYVE-rel	FGD1 FGD5 FGD3	3.40e-04	34	75	3	IPR017455
Domain	Znf_FYVE	FGD1 FGD5 FGD3	4.74e-04	38	75	3	IPR000306
Domain	ZF_FYVE	FGD1 FGD5 FGD3	5.52e-04	40	75	3	PS50178
Domain	Leu-rich_rpt_typical-subtyp	LRRC37A LRRC37A3 LRRC37A2 XRRA1 LRRC37B	7.30e-04	177	75	5	IPR003591
Domain	LRR_TYP	LRRC37A LRRC37A3 LRRC37A2 XRRA1 LRRC37B	7.30e-04	177	75	5	SM00369
Domain	LRR	LRRC37A LRRC37A3 LRRC37A2 XRRA1 LRRC37B	1.29e-03	201	75	5	PS51450
Domain	LRR_1	LRRC37A LRRC37A3 LRRC37A2 XRRA1 LRRC37B	1.88e-03	219	75	5	PF00560
Domain	L_dom-like	LRRC37A LRRC37A3 INSR LRRC37A2 XRRA1 LRRC37B	2.04e-03	328	75	6	IPR032675
Domain	RhoGEF	FGD1 FGD5 FGD3	2.58e-03	68	75	3	SM00325
Domain	RhoGEF	FGD1 FGD5 FGD3	2.81e-03	70	75	3	PF00621
Domain	DH_2	FGD1 FGD5 FGD3	2.81e-03	70	75	3	PS50010
Domain	DH-domain	FGD1 FGD5 FGD3	2.92e-03	71	75	3	IPR000219
Domain	-	FGD1 FGD5 FGD3	2.92e-03	71	75	3	1.20.900.10
Domain	Leu-rich_rpt	LRRC37A LRRC37A3 LRRC37A2 XRRA1 LRRC37B	4.68e-03	271	75	5	IPR001611
Domain	LRR_8	LRRC37A LRRC37A3 LRRC37A2 LRRC37B	4.98e-03	171	75	4	PF13855
Domain	-	IL1RAPL1 CSF1R NOMO2 IL21R INSR TNXB NOMO3 NOMO1	5.03e-03	663	75	8	2.60.40.10
Domain	Ig-like_fold	IL1RAPL1 CSF1R NOMO2 IL21R INSR TNXB NOMO3 NOMO1	7.27e-03	706	75	8	IPR013783
Pathway	REACTOME_BETA_OXIDATION_OF_LAUROYL_COA_TO_DECANOYL_COA_COA	ACADL HADHB	1.48e-04	5	55	2	M27721
Pathway	REACTOME_BETA_OXIDATION_OF_LAUROYL_COA_TO_DECANOYL_COA_COA	ACADL HADHB	1.48e-04	5	55	2	MM15463
Pathway	REACTOME_MRNA_CAPPING	ERCC2 ERCC3 RNMT	1.91e-04	29	55	3	M745
Pathway	REACTOME_MRNA_CAPPING	ERCC2 ERCC3 RNMT	1.91e-04	29	55	3	MM15409
Pathway	REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION_OF_UNSATURATED_FATTY_ACIDS	ACADL HADHB	2.22e-04	6	55	2	M27720
Pubmed	Evolutionary dynamism of the primate LRRC37 gene family.	LRRC37A LRRC37A3 LRRC37A2 LRRC37B	4.38e-09	10	76	4	23064749
Pubmed	Recurrent NOMO1 Gene Deletion Is a Potential Clinical Marker in Early-Onset Colorectal Cancer and Is Involved in the Regulation of Cell Migration.	NOMO2 NOMO3 NOMO1	1.00e-08	3	76	3	36011023
Pubmed	Silencing of nodal modulator 1 inhibits the differentiation of P19 cells into cardiomyocytes.	NOMO2 NOMO3 NOMO1	1.00e-08	3	76	3	25576386
Pubmed	Secretion of Annexin II via activation of insulin receptor and insulin-like growth factor receptor.	ANXA2 ANXA2P2 INSR	4.00e-08	4	76	3	12431980
Pubmed	Establishment of a conditional Nomo1 mouse model by CRISPR/Cas9 technology.	NOMO2 NOMO3 NOMO1	4.00e-08	4	76	3	31833031
Pubmed	Primate segmental duplication creates novel promoters for the LRRC37 gene family within the 17q21.31 inversion polymorphism region.	LRRC37A LRRC37A3 LRRC37A2	4.00e-08	4	76	3	22419166
Pubmed	A locus for autosomal recessive pseudoxanthoma elasticum, with penetrance of vascular symptoms in carriers, maps to chromosome 16p13.1.	NOMO2 NOMO3 NOMO1	4.00e-08	4	76	3	9267806
Pubmed	Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.	ACADL NOMO2 ANXA2 ANXA2P2 SEC11A ATL3 PIP5K1A SEC11C NEIL3 RAB1B HADHB EMD ME2 NOMO3 NOMO1 KPNB1	7.89e-08	1451	76	16	30550785
Pubmed	C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.	DDX19A ERCC2 SNW1 NOMO2 ANXA2 ANXA2P2 SEC11A HADHB EMD THOC2 DNA2 NOMO3 NOMO1 KPNB1	5.12e-07	1257	76	14	37317656
Pubmed	Nicalin and its binding partner Nomo are novel Nodal signaling antagonists.	NOMO2 NOMO3 NOMO1	5.57e-07	8	76	3	15257293
Pubmed	Substrate-driven assembly of a translocon for multipass membrane proteins.	NOMO2 NOMO3 NOMO1	8.34e-07	9	76	3	36261522
Pubmed	Isolation and characterization of two human transcription factor IIH (TFIIH)-related complexes: ERCC2/CAK and TFIIH.	ERCC2 ERCC3 ANXA2	1.19e-06	10	76	3	8692841
Pubmed	An ER translocon for multi-pass membrane protein biogenesis.	NOMO2 NOMO3 NOMO1	1.63e-06	11	76	3	32820719
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	DDX19A SNW1 ANXA2 SMCHD1 SEC11A FGD5 HADHB EMD GALNT5 THOC2 ME2 NOMO1 KPNB1 CHST13	2.24e-06	1425	76	14	30948266
Pubmed	Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.	TMEM120A UBE2I SMCHD1 SEC11A ATL3 FGD5 ANKRD23 TNXB NOMO3	3.32e-06	552	76	9	10737800
Pubmed	A competitive hexapeptide inhibitor of annexin A2 prevents hypoxia-induced angiogenic events.	ANXA2 ANXA2P2	4.71e-06	2	76	2	21486955
Pubmed	Polymorphisms in the two helicases ERCC2/XPD and ERCC3/XPB of the transcription factor IIH complex and risk of lung cancer: a case-control analysis in a Chinese population.	ERCC2 ERCC3	4.71e-06	2	76	2	16835333
Pubmed	Lipid raft endocytosis and exosomal transport facilitate extracellular trafficking of annexin A2.	ANXA2 ANXA2P2	4.71e-06	2	76	2	21737841
Pubmed	Vascular endothelial growth factor upregulates expression of annexin A2 in vitro and in a mouse model of ischemic retinopathy.	ANXA2 ANXA2P2	4.71e-06	2	76	2	19536308
Pubmed	Annexin A2 modulates radiation-sensitive transcriptional programming and cell fate.	ANXA2 ANXA2P2	4.71e-06	2	76	2	23148505
Pubmed	Regulation of the low-dose radiation paracrine-specific anchorage-independent growth response by annexin A2.	ANXA2 ANXA2P2	4.71e-06	2	76	2	19580511
Pubmed	ANXA2 (annexin A2) is crucial to ATG7-mediated autophagy, leading to tumor aggressiveness in triple-negative breast cancer cells.	ANXA2 ANXA2P2	4.71e-06	2	76	2	38290972
Pubmed	The cDNA sequence for the protein-tyrosine kinase substrate p36 (calpactin I heavy chain) reveals a multidomain protein with internal repeats.	ANXA2 ANXA2P2	4.71e-06	2	76	2	3013423
Pubmed	Activation of Annexin A2 signaling at the blood-brain barrier in a mouse model of multiple sclerosis.	ANXA2 ANXA2P2	4.71e-06	2	76	2	35064931
Pubmed	A 3' --> 5' XPB helicase defect in repair/transcription factor TFIIH of xeroderma pigmentosum group B affects both DNA repair and transcription.	ERCC2 ERCC3	4.71e-06	2	76	2	8663148
Pubmed	Complex Roles of Annexin A2 in Host Blood-Brain Barrier Invasion by Cryptococcus neoformans.	ANXA2 ANXA2P2	4.71e-06	2	76	2	28130864
Pubmed	Selenomethionine promotes ANXA2 phosphorylation for proliferation and protein synthesis of myoblasts and skeletal muscle growth.	ANXA2 ANXA2P2	4.71e-06	2	76	2	36739096
Pubmed	Comparative analyses of relative ERCC3 and ERCC6 mRNA levels in gliomas and adjacent non-neoplastic brain.	ERCC2 ERCC3	4.71e-06	2	76	2	8876669
Pubmed	Localization of annexin II in the paranodal regions and Schmidt-Lanterman incisures in the peripheral nervous system.	ANXA2 ANXA2P2	4.71e-06	2	76	2	17549680
Pubmed	Methionine-induced hyperhomocysteinemia reverts fibrinolytic pathway activation in a murine model of acute promyelocytic leukemia.	ANXA2 ANXA2P2	4.71e-06	2	76	2	22517898
Pubmed	Annexin A2 promotes proliferative vitreoretinopathy in response to a macrophage inflammatory signal in mice.	ANXA2 ANXA2P2	4.71e-06	2	76	2	39384746
Pubmed	Anxa2 gene silencing attenuates obesity-induced insulin resistance by suppressing the NF-κB signaling pathway.	ANXA2 ANXA2P2	4.71e-06	2	76	2	30462534
Pubmed	G quadruplexes are genomewide targets of transcriptional helicases XPB and XPD.	ERCC2 ERCC3	4.71e-06	2	76	2	24609361
Pubmed	Annexin A2 mediates up-regulation of NF-κB, β-catenin, and stem cell in response to progastrin in mice and HEK-293 cells.	ANXA2 ANXA2P2	4.71e-06	2	76	2	20826156
Pubmed	Lack of CAK complex accumulation at DNA damage sites in XP-B and XP-B/CS fibroblasts reveals differential regulation of CAK anchoring to core TFIIH by XPB and XPD helicases during nucleotide excision repair.	ERCC2 ERCC3	4.71e-06	2	76	2	23083890
Pubmed	Prohibitin/annexin 2 interaction regulates fatty acid transport in adipose tissue.	ANXA2 ANXA2P2	4.71e-06	2	76	2	27468426
Pubmed	Inhibition of the membrane repair protein annexin-A2 prevents tumor invasion and metastasis.	ANXA2 ANXA2P2	4.71e-06	2	76	2	38092984
Pubmed	Tyrosine 23 phosphorylation-dependent cell-surface localization of annexin A2 is required for invasion and metastases of pancreatic cancer.	ANXA2 ANXA2P2	4.71e-06	2	76	2	21572519
Pubmed	Homocysteine inhibits neoangiogenesis in mice through blockade of annexin A2-dependent fibrinolysis.	ANXA2 ANXA2P2	4.71e-06	2	76	2	19841537
Pubmed	Hypoxia-inducible factor-1 drives annexin A2 system-mediated perivascular fibrin clearance in oxygen-induced retinopathy in mice.	ANXA2 ANXA2P2	4.71e-06	2	76	2	21788340
Pubmed	The Membrane Phospholipid Binding Protein Annexin A2 Promotes Phagocytosis and Nonlytic Exocytosis of Cryptococcus neoformans and Impacts Survival in Fungal Infection.	ANXA2 ANXA2P2	4.71e-06	2	76	2	27371724
Pubmed	Trichothiodystrophy, a transcription syndrome.	ERCC2 ERCC3	4.71e-06	2	76	2	11335038
Pubmed	Annexin A2 Modulates ROS and Impacts Inflammatory Response via IL-17 Signaling in Polymicrobial Sepsis Mice.	ANXA2 ANXA2P2	4.71e-06	2	76	2	27389701
Pubmed	Transcriptional regulation of the TFIIH transcription repair components XPB and XPD by the hepatitis B virus x protein in liver cells and transgenic liver tissue.	ERCC2 ERCC3	4.71e-06	2	76	2	11278765
Pubmed	Role of ERCC2 and ERCC3 gene polymorphisms in the development of osteosarcoma.	ERCC2 ERCC3	4.71e-06	2	76	2	27051024
Pubmed	Annexin A2 Deficiency Exacerbates Neuroinflammation and Long-Term Neurological Deficits after Traumatic Brain Injury in Mice.	ANXA2 ANXA2P2	4.71e-06	2	76	2	31817350
Pubmed	ANNEXIN A2 FACILITATES NEOVASCULARIZATION TO PROTECT AGAINST MYOCARDIAL INFARCTION INJURY VIA INTERACTING WITH MACROPHAGE YAP AND ENDOTHELIAL INTEGRIN Β3.	ANXA2 ANXA2P2	4.71e-06	2	76	2	37832154
Pubmed	Annexin II expressed by osteoblasts and endothelial cells regulates stem cell adhesion, homing, and engraftment following transplantation.	ANXA2 ANXA2P2	4.71e-06	2	76	2	17360942
Pubmed	Annexin A2 regulates phagocytosis of photoreceptor outer segments in the mouse retina.	ANXA2 ANXA2P2	4.71e-06	2	76	2	19587120
Pubmed	Phenotype-specific adverse effects of XPD mutations on human prenatal development implicate impairment of TFIIH-mediated functions in placenta.	ERCC2 ERCC3	4.71e-06	2	76	2	22234153
Pubmed	Cell-surface translocation of annexin A2 contributes to bleomycin-induced pulmonary fibrosis by mediating inflammatory response in mice.	ANXA2 ANXA2P2	4.71e-06	2	76	2	30902828
Pubmed	Annexin A2 at the interface between F-actin and membranes enriched in phosphatidylinositol 4,5,-bisphosphate.	ANXA2 ANXA2P2	4.71e-06	2	76	2	19022301
Pubmed	Cell surface translocation of annexin A2 facilitates glutamate-induced extracellular proteolysis.	ANXA2 ANXA2P2	4.71e-06	2	76	2	24742684
Pubmed	Annexin A2 depletion exacerbates the intracerebral microhemorrhage induced by acute rickettsia and Ebola virus infections.	ANXA2 ANXA2P2	4.71e-06	2	76	2	32687500
Pubmed	Annexin A2 binds to endosomes following organelle destabilization by particulate wear debris.	ANXA2 ANXA2P2	4.71e-06	2	76	2	22453828
Pubmed	Multi-Omics Profiling Identifies Microglial Annexin A2 as a Key Mediator of NF-κB Pro-inflammatory Signaling in Ischemic Reperfusion Injury.	ANXA2 ANXA2P2	4.71e-06	2	76	2	38253182
Pubmed	TMEM120A and B: Nuclear Envelope Transmembrane Proteins Important for Adipocyte Differentiation.	TMEM120B TMEM120A	4.71e-06	2	76	2	26024229
Pubmed	Agents that bind annexin A2 suppress ocular neovascularization.	ANXA2 ANXA2P2	4.71e-06	2	76	2	20607799
Pubmed	A new role for host annexin A2 in establishing bacterial adhesion to vascular endothelial cells: lines of evidence from atomic force microscopy and an in vivo study.	ANXA2 ANXA2P2	4.71e-06	2	76	2	31253864
Pubmed	Cryo-EM structures of human TMEM120A and TMEM120B.	TMEM120B TMEM120A	4.71e-06	2	76	2	34465718
Pubmed	XPB mediated retroviral cDNA degradation coincides with entry to the nucleus.	ERCC2 ERCC3	4.71e-06	2	76	2	21167544
Pubmed	Annexin A2 is a novel cellular redox regulatory protein involved in tumorigenesis.	ANXA2 ANXA2P2	4.71e-06	2	76	2	22185818
Pubmed	Two subunits of the canine signal peptidase complex are homologous to yeast SEC11 protein.	SEC11A SEC11C	4.71e-06	2	76	2	2188978
Pubmed	Annexin A2 is involved in antiphospholipid antibody-mediated pathogenic effects in vitro and in vivo.	ANXA2 ANXA2P2	4.71e-06	2	76	2	19628708
Pubmed	Annexin A2 binds to the localization signal in the 3' untranslated region of c-myc mRNA.	ANXA2 ANXA2P2	4.71e-06	2	76	2	15654879
Pubmed	Haplotype analysis on relationship of ERCC2 and ERCC3 gene polymorphisms with osteosarcoma risk in Chinese young population.	ERCC2 ERCC3	4.71e-06	2	76	2	28474168
Pubmed	Anti-dsDNA antibodies bind to mesangial annexin II in lupus nephritis.	ANXA2 ANXA2P2	4.71e-06	2	76	2	20847146
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	DDX19A SNW1 SMCHD1 SEC11A ATL3 PIP5K1A NCK1 EMD CDC25A NOMO1 KPNB1	8.54e-06	974	76	11	28675297
Pubmed	STARD3NL inhibits the osteogenic differentiation by inactivating the Wnt/β-catenin pathway via binding to Annexin A2 in osteoporosis.	ANXA2 ANXA2P2	1.41e-05	3	76	2	35098646
Pubmed	Annexin A2 promotes angiogenesis after ischemic stroke via annexin A2 receptor - AKT/ERK pathways.	ANXA2 ANXA2P2	1.41e-05	3	76	2	36367512
Pubmed	Revealing Annexin A2 and ARF-6 enrollment during Trypanosoma cruzi extracellular amastigote-host cell interaction.	ANXA2 ANXA2P2	1.41e-05	3	76	2	26416603
Pubmed	Annexin A2 depletion delays EGFR endocytic trafficking via cofilin activation and enhances EGFR signaling and metastasis formation.	ANXA2 ANXA2P2	1.41e-05	3	76	2	23792445
Pubmed	The Annexin A2-Notch regulatory loop in hepatocytes promotes liver fibrosis in NAFLD by increasing osteopontin expression.	ANXA2 ANXA2P2	1.41e-05	3	76	2	35413401
Pubmed	Annexin A2 supports pulmonary microvascular integrity by linking vascular endothelial cadherin and protein tyrosine phosphatases.	ANXA2 ANXA2P2	1.41e-05	3	76	2	28694388
Pubmed	High Podocalyxin levels promote cell viability partially through up-regulation of Annexin A2.	ANXA2 ANXA2P2	1.41e-05	3	76	2	27470587
Pubmed	Annexin 2-CXCL12 interactions regulate metastatic cell targeting and growth in the bone marrow.	ANXA2 ANXA2P2	1.41e-05	3	76	2	25139998
Pubmed	Annexins--unique membrane binding proteins with diverse functions.	ANXA2 ANXA2P2	1.41e-05	3	76	2	15169834
Pubmed	Annexin A2 reduces PCSK9 protein levels via a translational mechanism and interacts with the M1 and M2 domains of PCSK9.	ANXA2 ANXA2P2	1.41e-05	3	76	2	24808179
Pubmed	Impaired osteoblast differentiation in annexin A2- and -A5-deficient cells.	ANXA2 ANXA2P2	1.41e-05	3	76	2	25222280
Pubmed	The Annexin a2 Promotes Development in Arthritis through Neovascularization by Amplification Hedgehog Pathway.	ANXA2 ANXA2P2	1.41e-05	3	76	2	26963384
Pubmed	Distinct roles for the XPB/p52 and XPD/p44 subcomplexes of TFIIH in damaged DNA opening during nucleotide excision repair.	ERCC2 ERCC3	1.41e-05	3	76	2	17466626
Pubmed	Macrophage surface expression of annexins I and II in the phagocytosis of apoptotic lymphocytes.	ANXA2 ANXA2P2	1.41e-05	3	76	2	15064349
Pubmed	Annexin A2 links poor myofiber repair with inflammation and adipogenic replacement of the injured muscle.	ANXA2 ANXA2P2	1.41e-05	3	76	2	28334824
Pubmed	Tenascin-c renders a proangiogenic phenotype in macrophage via annexin II.	ANXA2 ANXA2P2	1.41e-05	3	76	2	28857429
Pubmed	Fibroadipogenic progenitors are responsible for muscle loss in limb girdle muscular dystrophy 2B.	ANXA2 ANXA2P2	1.41e-05	3	76	2	31160583
Pubmed	TFIIH subunit alterations causing xeroderma pigmentosum and trichothiodystrophy specifically disturb several steps during transcription.	ERCC2 ERCC3	1.41e-05	3	76	2	25620205
Pubmed	Inhibition of ANXA2 regulated by SRF attenuates the development of severe acute pancreatitis by inhibiting the NF-κB signaling pathway.	ANXA2 ANXA2P2	1.41e-05	3	76	2	35900381
Pubmed	ARCH domain of XPD, an anchoring platform for CAK that conditions TFIIH DNA repair and transcription activities.	ERCC2 ERCC3	1.41e-05	3	76	2	23382212
Pubmed	Annexin II interactions with the annexin II receptor enhance multiple myeloma cell adhesion and growth in the bone marrow microenvironment.	ANXA2 ANXA2P2	1.41e-05	3	76	2	22223826
Pubmed	Annexin A2 promotes phagophore assembly by enhancing Atg16L⁺ vesicle biogenesis and homotypic fusion.	ANXA2 ANXA2P2	1.41e-05	3	76	2	25597631
Pubmed	Generation of DNA single-strand displacement by compromised nucleotide excision repair.	ERCC2 ERCC3	1.41e-05	3	76	2	22863773
Pubmed	Annexin A2 regulates TRPA1-dependent nociception.	ANXA2 ANXA2P2	1.41e-05	3	76	2	25355205
Pubmed	Complete structure of the murine p36 (annexin II) gene. Identification of mRNAs for both the murine and the human gene with alternatively spliced 5' noncoding exons.	ANXA2 ANXA2P2	1.41e-05	3	76	2	8634333
Pubmed	RNASEH1-AS1 induced by H3K27ac stabilizes ANXA2 mRNA to promote the progression of colorectal cancer through recruiting BUD13.	ANXA2 ANXA2P2	1.41e-05	3	76	2	38053379
Pubmed	Chromosomal localization of the human genes for lipocortin I and lipocortin II.	ANXA2 ANXA2P2	1.41e-05	3	76	2	2969496
Pubmed	Signal peptidase complex 18, encoded by SEC11A, contributes to progression via TGF-α secretion in gastric cancer.	SEC11A SEC11C	1.41e-05	3	76	2	23995782
Pubmed	Upregulation of HDAC9 in hippocampal neurons mediates depression-like behaviours by inhibiting ANXA2 degradation.	ANXA2 ANXA2P2	1.41e-05	3	76	2	37690046
Pubmed	Basal transcription defect discriminates between xeroderma pigmentosum and trichothiodystrophy in XPD patients.	ERCC2 ERCC3	1.41e-05	3	76	2	12820975
Pubmed	Annexin-2 is a regulator of stromal cell-derived factor-1/CXCL12 function in the hematopoietic stem cell endosteal niche.	ANXA2 ANXA2P2	1.41e-05	3	76	2	21108988
Pubmed	The Tick Protein Sialostatin L2 Binds to Annexin A2 and Inhibits NLRC4-Mediated Inflammasome Activation.	ANXA2 ANXA2P2	1.41e-05	3	76	2	27045038
Interaction	NCLN interactions	TMEM120B TMEM120A NOMO2 SEC11A SEC11C NOMO3 NOMO1	5.35e-06	183	75	7	int:NCLN
Interaction	NR3C1 interactions	IL1RAPL1 DDX19A UBE2I LRRC37A3 SMCHD1 SEC11A FBXO42 FGD5 RAB1B HADHB ARPC5 NOMO3 FER1L6 KPNB1	1.23e-05	974	75	14	int:NR3C1
GeneFamily	Zinc fingers FYVE-type\|Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors	FGD1 FGD5 FGD3	5.76e-05	31	44	3	81
GeneFamily	WD repeat domain containing\|ERCC excision repair associated	ERCC2 ERCC3	1.21e-04	7	44	2	1268
GeneFamily	WD repeat domain containing\|Xeroderma pigmentosum complementation groups\|Nucleotide excision repair	ERCC2 ERCC3	1.61e-04	8	44	2	1125
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	FGD1 FGD5 FGD3	5.53e-04	66	44	3	722
GeneFamily	DNA helicases	ERCC2 ERCC3	7.69e-04	17	44	2	1167
GeneFamily	General transcription factors\|Xeroderma pigmentosum complementation groups\|DNA helicases\|ERCC excision repair associated	ERCC2 ERCC3	1.68e-03	25	44	2	565
GeneFamily	Receptor Tyrosine Kinases\|CD molecules	CSF1R INSR	4.26e-03	40	44	2	321
GeneFamily	CD molecules\|I-set domain containing\|Immunoglobulin like domain containing\|Interleukin receptors\|TIR domain containing	IL1RAPL1 IL21R	4.68e-03	42	44	2	602
GeneFamily	X-linked mental retardation\|Angiotensin receptors	IL1RAPL1 THOC2	7.37e-03	53	44	2	103
Coexpression	NAKAYA_PBMC_FLUARIX_FLUVIRIN_AGE_18_50YO_CORRELATED_WITH_HAI_28DY_RESPONSE_AT_7DY_POSITIVE	CSF1R NOMO2 SEC11C NOMO3 NOMO1 DNAH1	7.77e-06	162	76	6	M41204
ToppCell	NS-moderate-d_16-33-Epithelial-Secretory\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	INSR PRSS23 GALNT5 FER1L6 MYO5C	2.14e-05	196	76	5	70384c1da9baed843f414cfd1403ddd586a2db07
ToppCell	BAL-Severe-Epithelial-Epithelial-transitional_Epi\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PRSS23 GALNT5 SLC44A4 FER1L6 MYO5C	2.14e-05	196	76	5	3e99a367b7d817e1f1221450fcec20ad7a7c7a2a
ToppCell	BAL-Severe-Epithelial-Epithelial-transitional_Epi-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PRSS23 GALNT5 SLC44A4 FER1L6 MYO5C	2.14e-05	196	76	5	1efacc37bbfbd05b5d4db3dd10f6d9a238d23e31
ToppCell	Severe_COVID-19-Epithelial-transitional_Epi\|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）	PRSS23 GALNT5 SLC44A4 FER1L6 MYO5C	2.20e-05	197	76	5	5ad3cd4c77016e862041baac3076f8cc0f75c417
ToppCell	BAL-Severe-Epithelial-Epithelial-transitional_Epi-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	PRSS23 GALNT5 SLC44A4 FER1L6 MYO5C	2.20e-05	197	76	5	08b371309cd790b171ed76cabc7d910e71cd2835
ToppCell	BAL-Severe-Epithelial-Epithelial-transitional_Epi\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	PRSS23 GALNT5 SLC44A4 FER1L6 MYO5C	2.20e-05	197	76	5	9f49feee38647bbf964974aac96fa75602186b5c
ToppCell	BL-critical-LOC-Epithelial-Secretory_LYPD2\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ANXA2 PRSS23 GALNT5 SLC44A4 FER1L6	2.25e-05	198	76	5	484d16aaa601a1e11b871b0475dd01a2de1a29ce
ToppCell	NS-critical-LOC-Epithelial-Secretory_LYPD2\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ANXA2 PRSS23 GALNT5 SLC44A4 FER1L6	2.25e-05	198	76	5	4a481e1edb80b950c823ed926842cd5132cfb27f
ToppCell	NS-control-d_0-4-Epithelial\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ANXA2 PRSS23 GALNT5 SLC44A4 MYO5C	2.36e-05	200	76	5	d014959891893b6d3854a471fba1dc50c6625a0a
ToppCell	NS-moderate-d_16-33-Epithelial-Secretory-diff\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ANXA2 PRSS23 GALNT5 SLC44A4 FER1L6	2.36e-05	200	76	5	8f179b5768fd504af6dd6f6749a0bed7b689e77f
ToppCell	Substantia_nigra-Macroglia-OLIGODENDROCYTE\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	FOLH1 SEC11C GALNT5 FGD3	3.93e-05	111	76	4	4a22732094a9781867d501d9c05ba652c2f25048
ToppCell	Thalamus-Macroglia-OLIGODENDROCYTE-O1-Trf\|Thalamus / BrainAtlas - Mouse McCarroll V32	FOLH1 SEC11C NEIL3 GALNT5	4.07e-05	112	76	4	cb351e57c99aaaf9ae6c7ff7e8ce5375552b1639
ToppCell	Thalamus-Macroglia-OLIGODENDROCYTE-O1-Trf-Oligodendrocyte.Trf.Il33_(Il33)\|Thalamus / BrainAtlas - Mouse McCarroll V32	FOLH1 SEC11C NEIL3 GALNT5	4.07e-05	112	76	4	999b5eeed4305e1a1385aadbaf017b64f21c1ee0
ToppCell	Thalamus-Macroglia-OLIGODENDROCYTE-O1-Trf-Oligodendrocyte.Trf.Il33_(Il33)-\|Thalamus / BrainAtlas - Mouse McCarroll V32	FOLH1 SEC11C NEIL3 GALNT5	4.07e-05	112	76	4	004cd69b66c3b26b9a61f03279b48230da351574
ToppCell	Thalamus-Macroglia-OLIGODENDROCYTE-O1\|Thalamus / BrainAtlas - Mouse McCarroll V32	FOLH1 SEC11C NEIL3 GALNT5	4.07e-05	112	76	4	502e3f356f6e1c959bff0a39c98f33f863ce8265
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Vipr2\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ANXA2 NEK7 ENPEP FGD3	5.15e-05	119	76	4	6425425b2e622c97b6c74c530ccbfe394d3b202d
ToppCell	Entopeduncular-Macroglia-OLIGODENDROCYTE\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	FOLH1 SEC11C GALNT5 FGD3	7.27e-05	130	76	4	0a6b87635e650df431a88f2e6396abead84d901d
ToppCell	Entopeduncular-Endothelial-MURAL-M1(Rgs5Acta2)-M1_1-MURAL_Mural.Rgs5Acta2.Junb_(Mural,_IEG+)\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	SMCHD1 ANKRD23 EMD ENPEP	1.47e-04	156	76	4	029ba0832ee9c4a2c85620e4df2260e02d86b45c
ToppCell	Entopeduncular-Endothelial-MURAL-M1(Rgs5Acta2)-M1_1-MURAL_Mural.Rgs5Acta2.Junb_(Mural,_IEG+)-\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	SMCHD1 ANKRD23 EMD ENPEP	1.47e-04	156	76	4	5df19a235843829f5a1a90ca21b0964ef8b4e115
ToppCell	356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	CSF1R TNXB F8 MYO5C	1.58e-04	159	76	4	1472536eea61d4f13033efe42f128bae1614fa74
ToppCell	facs-Lung-EPCAM-3m-Endothelial-Capillary_Type_1_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CPA2 NEIL3 ME2 FGD3	1.66e-04	161	76	4	a7e74bc80ac11250e353e5614b19c05793fc2e95
ToppCell	3'-Adult-SmallIntestine-Epithelial-mature_enterocytic-Paneth\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FOLH1 CDC25A ENPEP CHST13	1.70e-04	162	76	4	768a566e76923323c1f197f60bab472a8784490b
ToppCell	367C-Myeloid-Monocyte-CD16+_Monocyte\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	KCTD7 LRRC37A LRRC37A2 XRRA1	1.78e-04	164	76	4	1aff83fc73b4e41e6f0d4b04dbca153bcc7a3518
ToppCell	saliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TSNAXIP1 IFT122 CFAP46 DNAH1	1.95e-04	168	76	4	9a8709d34865cfa668d8f3335dc34fc86fc32482
ToppCell	droplet-Lung-1m-Hematologic-myeloid-interstitial_macrophage\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KCTD7 TMEM120B CSF1R IL21R	2.04e-04	170	76	4	f664c7559e383b37845c123e41a3be316d869ba0
ToppCell	droplet-Lung-1m-Hematologic-myeloid-interstitial_macrophage-interstitial_macrophage_l12\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KCTD7 TMEM120B CSF1R IL21R	2.04e-04	170	76	4	0272eb1487c2545d4aa06f5d1cd77f823e1441e9
ToppCell	Hippocampus-Macroglia-OLIGODENDROCYTE-O1-Trf\|Hippocampus / BrainAtlas - Mouse McCarroll V32	FOLH1 SEC11C GALNT5	2.15e-04	68	76	3	31f9f6b4473970473f89b67643bb55dc332732d8
ToppCell	Hippocampus-Macroglia-OLIGODENDROCYTE-O1-Trf-Oligodendrocyte.Trf.Il33_(Il33)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	FOLH1 SEC11C GALNT5	2.15e-04	68	76	3	91a500a68245a8a484a537aad2cc8b62ff4579f0
ToppCell	Hippocampus-Macroglia-OLIGODENDROCYTE-O1-Trf-Oligodendrocyte.Trf.Il33_(Il33)-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	FOLH1 SEC11C GALNT5	2.15e-04	68	76	3	a89cc6fb62f50ea4124b1a6b0b30cd7ceb52e408
ToppCell	Hippocampus-Macroglia-OLIGODENDROCYTE-O1\|Hippocampus / BrainAtlas - Mouse McCarroll V32	FOLH1 SEC11C GALNT5	2.15e-04	68	76	3	3d148bb49246c3fac9a1e864ecc5e15b29863c52
ToppCell	Adult-Epithelial-lung_goblet_cell-D231\|Adult / Lineage, Cell type, age group and donor	INSR PRSS23 SLC44A4 FER1L6	2.23e-04	174	76	4	7d2f802f493f19a068e097b2909a9000e2160266
ToppCell	368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-\|368C / Donor, Lineage, Cell class and subclass (all cells)	ACADL NEIL3 GALNT5 MYO5C	2.28e-04	175	76	4	fd8b5b756f3df4a04938785f3d9edbb6f1cd20f6
ToppCell	368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)\|368C / Donor, Lineage, Cell class and subclass (all cells)	ACADL NEIL3 GALNT5 MYO5C	2.28e-04	175	76	4	36c140540497bbe1c5f08fac2d94f08cac18fabb
ToppCell	tumor_Lung-Endothelial_cells-EPCs\|tumor_Lung / Location, Cell class and cell subclass	LRRC37A3 INSR PRSS23 F8	2.38e-04	177	76	4	f8b152c09d56a97e8c0482fb1a3964c05f9dc8c5
ToppCell	droplet-Fat-BAT+GAT+MAT-30m-Epithelial\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TSNAXIP1 GOT1L1 GALNT5 CFAP46	2.43e-04	178	76	4	58857bb8c13e0e1c6d9f5c1258f00fff62063d68
ToppCell	droplet-Fat-BAT+GAT+MAT-30m-Epithelial-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TSNAXIP1 GOT1L1 GALNT5 CFAP46	2.43e-04	178	76	4	8b7df6ab8709d9ab9dff97677cc4561aec2745bc
ToppCell	droplet-Fat-BAT+GAT+MAT-30m-Epithelial-epithelial_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TSNAXIP1 GOT1L1 GALNT5 CFAP46	2.43e-04	178	76	4	b0baf5667e3301898b3e45e974b8a8530af6a338
ToppCell	Adult-Epithelial-lung_goblet_cell\|Adult / Lineage, Cell type, age group and donor	INSR PRSS23 SLC44A4 FER1L6	2.49e-04	179	76	4	1fc1f252ca943a2f649d1e627f56acbf15f8e058
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TSNAXIP1 SLC44A4 CFAP46 DNAH1	2.54e-04	180	76	4	92fb01b91261b3103454924cde56add337b41844
ToppCell	3'-GW_trimst-2-LargeIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ANXA2 PRSS23 TNXB F8	2.76e-04	184	76	4	3b0389c3a5a16697de860e98ebc48ed39ede646f
ToppCell	droplet-Thymus-nan-3m-Lymphocytic-nan\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STON1 ANXA2 IL21R XRRA1	2.82e-04	185	76	4	aa2c36e2cce0f0a536cd1dfc3788b6fee6f21b6b
ToppCell	Substantia_nigra-Macroglia-OLIGODENDROCYTE-O1-Tfr-Oligodendrocyte.Tfr.Slco3a1_(Slco3a1)-\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	FOLH1 SEC11C GALNT5	2.87e-04	75	76	3	574ed1836f6bf5fa38a53af0a05fa4437f68f36b
ToppCell	Substantia_nigra-Macroglia-OLIGODENDROCYTE-O1-Tfr-Oligodendrocyte.Tfr.Slco3a1_(Slco3a1)\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	FOLH1 SEC11C GALNT5	2.87e-04	75	76	3	45f7861bfeb1c6371b73cf2ea527801342e534bc
ToppCell	Entopeduncular-Macroglia-OLIGODENDROCYTE-O1-Trf\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	FOLH1 SEC11C GALNT5	2.98e-04	76	76	3	efbbbf91bca35720d8ecddb076f2c9f4de25e44d
ToppCell	Entopeduncular-Macroglia-OLIGODENDROCYTE-O1\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	FOLH1 SEC11C GALNT5	2.98e-04	76	76	3	254d18bece2676faa4bbeb8d48b1d327ab3c2215
ToppCell	Striatum-Endothelial\|Striatum / BrainAtlas - Mouse McCarroll V32	STON1 ANXA2 PRSS23 ENPEP	3.06e-04	189	76	4	95ee3b6d7fbbfcf91c780dfcd0926acec05f0a2d
ToppCell	BL-critical-LOC-Epithelial-Secretory\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	PRSS23 GALNT5 FER1L6 MYO5C	3.12e-04	190	76	4	f2abe4bc28e934287e2dcd7b9399d5af78c5c8cf
ToppCell	wk_20-22-Endothelial-Lymph_endothelial\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	ANXA2 PRSS23 TNXB F8	3.18e-04	191	76	4	631f95fd80dd3678b5b2ef201abf7fe646049af6
ToppCell	NS-critical-d_16-33-Epithelial-Secretory-diff\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ANXA2 PRSS23 GALNT5 FER1L6	3.24e-04	192	76	4	02b11233b4da2d85b96498b3c6e22e3a31b3d049
ToppCell	IPF-Endothelial-VE_Arterial\|Endothelial / Disease state, Lineage and Cell class	TMEM120A NOMO2 NOMO3 NOMO1	3.24e-04	192	76	4	e911e286da26202853f9650ba3cdefe5a5c9b585
ToppCell	5'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ANXA2 PRSS23 TNXB F8	3.24e-04	192	76	4	5388f3115ab285f3f3001af1d71543ed64b9e044
ToppCell	5'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ANXA2 PRSS23 TNXB F8	3.31e-04	193	76	4	ef007b736da56529ec628fc3df86a335e7ec3f18
ToppCell	3'-Child04-06-SmallIntestine-Epithelial-goblet-Goblet_cell\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GALNT5 SLC44A4 FER1L6 MYO5C	3.37e-04	194	76	4	49cc5f5de4380302100e8cd937f08abe317ac75e
ToppCell	3'-Child04-06-SmallIntestine-Epithelial-goblet\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GALNT5 SLC44A4 FER1L6 MYO5C	3.37e-04	194	76	4	fb935df966c451e659b8bde281f8aebcb632f6cf
ToppCell	moderate-Epithelial-FOXN4+\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	COG7 IFT122 CFAP46 MYO5C	3.37e-04	194	76	4	5dffa578149104dda33774361e9e77b227b5f1ce
ToppCell	cellseq-Epithelial-Epithelial_Glandular\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	FOLH1 PRSS23 SLC44A4 FER1L6	3.37e-04	194	76	4	d0fb1ff5cf0738881e114a58f0b27489f781d72b
ToppCell	wk_20-22-Endothelial-Lymph_endothelial-Lymphatic_endo\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	ANXA2 PRSS23 TNXB F8	3.37e-04	194	76	4	640ff8da7084a9486fc2752493b8d8059ecf4ab7
ToppCell	COVID-19-kidney-PLVAP+EC\|kidney / Disease (COVID-19 only), tissue and cell type	SMCHD1 INSR FGD5 F8	3.44e-04	195	76	4	a436483fec137584611f86b7a498a4dc2aa19cd3
ToppCell	5'-GW_trimst-2-LargeIntestine-Epithelial-goblet-Goblet_cell\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GALNT5 SLC44A4 FER1L6 MYO5C	3.44e-04	195	76	4	7ff04c45a02df01e3816f3c1d43585a93182a730
ToppCell	facs-Aorta-Heart-3m-Endothelial\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	INSR FGD5 ENPEP F8	3.44e-04	195	76	4	8493f2f60fc356af28b9c0e287d4cd8c8899c081
ToppCell	NS-critical-LOC-Epithelial-Secretory\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	PRSS23 GALNT5 SLC44A4 FER1L6	3.44e-04	195	76	4	b0d782eeee30c797b4da9b3be29b864983fd9e71
ToppCell	5'-GW_trimst-2-LargeIntestine-Epithelial-goblet\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GALNT5 SLC44A4 FER1L6 MYO5C	3.44e-04	195	76	4	09605533aa5947bb2e5a6725c1ce89f79d330bf5
ToppCell	10x5'\|World / Manually curated celltypes from each tissue	SLC25A32 FAM120B IL21R RAB1B	3.44e-04	195	76	4	de28b998793271c4f69ce9e183c3e62d809e9cc8
ToppCell	facs-Aorta-Heart-3m-Endothelial-aortic_endothelial_cell\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	INSR FGD5 ENPEP F8	3.44e-04	195	76	4	5e5ca7bd94c9e924ed76f7ccac199be745d4c4eb
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	INSR PRSS23 SLC44A4 FER1L6	3.51e-04	196	76	4	c18874f37b90e6afacc562b2082b67ea8a7cb4a4
ToppCell	background-Endothelial_cells\|background / Sample and Cell Type and Tumor Cluster (all cells)	INSR FGD5 PRSS23 F8	3.51e-04	196	76	4	e6fb0bfab1779ec64a8c35d01519eaafbf62e977
ToppCell	5'-Adult-LargeIntestine-Epithelial-goblet\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GALNT5 SLC44A4 FER1L6 MYO5C	3.51e-04	196	76	4	847b3377f463bfded046eec63cc1b547f3dc33c1
ToppCell	COVID-19-Epithelial-Club,_Basal_cells\|COVID-19 / Condition, Lineage and Cell class	FOLH1 PRSS23 SLC44A4 FER1L6	3.51e-04	196	76	4	dd32046067d93b9484cfbf1d7826a436a3d9f0e9
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PRSS23 GALNT5 SLC44A4 FER1L6	3.51e-04	196	76	4	a52879a4c822c5e4be569f01f845a795e00c5f4b
ToppCell	wk_15-18-Endothelial-Lymph_endothelial\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	ANXA2 PRSS23 TNXB F8	3.51e-04	196	76	4	ff627244d7f5fd6a2ec009dae32d3509f0e2d95e
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PRSS23 GALNT5 SLC44A4 FER1L6	3.51e-04	196	76	4	7a4d502550e9e37dc42f2ff1be3c896afe365d7f
ToppCell	Bronchial_Biopsy-Epithelial-Club\|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X	INSR PRSS23 SLC44A4 FER1L6	3.51e-04	196	76	4	057d150bdf0cad959fd03ec2d1560a96ba03fae9
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PRSS23 GALNT5 SLC44A4 FER1L6	3.51e-04	196	76	4	60ea673ed887fe3890c5cf4ff4165384b76d7361
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-B\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	IL1RAPL1 OR2L2 FOLH1 PNLDC1	3.58e-04	197	76	4	032ccc91e604113da9bc34a6f9ddb1d45dea1892
ToppCell	5'-Adult-LargeIntestine-Epithelial-goblet-BEST2+_Goblet_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GALNT5 SLC44A4 FER1L6 MYO5C	3.58e-04	197	76	4	d624f3a105b19f19a0dd253ce8de3ed13adc1f01
ToppCell	COVID_vent-Lymphocytic-Plasma_cell-IgA_Plasmablast\|COVID_vent / Disease condition, Lineage, Cell class and subclass	NOMO2 SEC11C NOMO3 NOMO1	3.58e-04	197	76	4	99fe44ef42c65d24fe64947fd5bf6d91b9a4b2c3
ToppCell	Bronchial_Biopsy-Epithelial-Club\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	INSR PRSS23 SLC44A4 FER1L6	3.58e-04	197	76	4	3f5dfa892a1f631b96eeb6f4cfc284aee51d1ce6
ToppCell	Tracheal-10x5prime-Epithelial-Epi_airway_ciliated-Deuterosomal\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	LRRC37A LRRC37A3 CFAP46 DNAH1	3.58e-04	197	76	4	6e4a411ef823ce9e16f420e185e21fa19d13af34
ToppCell	Control_saline-Epithelial_alveolar-AT_1-Differentiating_AT1\|Control_saline / Treatment groups by lineage, cell group, cell type	ANXA2 GALNT5 FGD3 MYO5C	3.64e-04	198	76	4	85f424cd9bb3117c9e322031024aabb87696ce47
ToppCell	moderate-Epithelial-Secretory\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	PRSS23 GALNT5 SLC44A4 FER1L6	3.64e-04	198	76	4	7d96d7105a849c7280ce87bd76ce130ac47384fd
ToppCell	3'-Adult-Distal_Rectal\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ANXA2 INSR GALNT5 SLC44A4	3.64e-04	198	76	4	7ad7726fc405806b1d7824f58548073ea5e0c70b
ToppCell	3'-Adult-Distal_Rectal-Epithelial-epithelial_progenitor_cell-TA\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ANXA2 INSR GALNT5 SLC44A4	3.64e-04	198	76	4	1fbec311f2c987ca90a023a5989128c05aa12d5c
ToppCell	Control_saline-Epithelial_alveolar-AT_1\|Control_saline / Treatment groups by lineage, cell group, cell type	ANXA2 GALNT5 FGD3 MYO5C	3.64e-04	198	76	4	9b161285df7a4e51618f3517cfc5b8221ba55786
ToppCell	LPS_only-Epithelial_airway-airway_epithelial-Ciliated\|LPS_only / Treatment groups by lineage, cell group, cell type	TSNAXIP1 INSR IFT122 DNAH1	3.64e-04	198	76	4	6d90b541fde357fbb40f8f7d4e8628a48b679718
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-secretory_cell-Epi-Secretory\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	PRSS23 GALNT5 SLC44A4 MYO5C	3.64e-04	198	76	4	270cecff42b87b7e03f09dd9f99547b287b4598c
ToppCell	3'-Adult-Distal_Rectal-Epithelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ANXA2 INSR GALNT5 SLC44A4	3.64e-04	198	76	4	ceede961ad9af6a3159db7efaa5087bf38aafc2d
ToppCell	3'-Adult-Distal_Rectal-Epithelial-epithelial_progenitor_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ANXA2 INSR GALNT5 SLC44A4	3.64e-04	198	76	4	4f26a60e99f42343e5af7221723e108a1a1b7827
ToppCell	Control_saline-Epithelial_alveolar\|Control_saline / Treatment groups by lineage, cell group, cell type	ANXA2 GALNT5 FGD3 MYO5C	3.64e-04	198	76	4	532b7ef4ad46fe35ad2c6bdf89f70a17f1a2e2e2
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-secretory_cell\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	PRSS23 GALNT5 SLC44A4 MYO5C	3.64e-04	198	76	4	8b3f4effaaccf8777cde854d5d8a765962f7312b
ToppCell	BAL-Severe-Epithelial-Epithelial-Basal/Club\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PRSS23 GALNT5 SLC44A4 MYO5C	3.71e-04	199	76	4	d04062d86643e5712cc2f519f4f36e643d404a16
ToppCell	3'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ANXA2 PRSS23 ENPEP TNXB	3.71e-04	199	76	4	bfc157be6e9f84739848eb19b718de5b17f3fa88
ToppCell	LPS_IL1RA-Epithelial_alveolar-AT_1-2_Progenitor\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ANXA2 SEC11C GALNT5 MYO5C	3.71e-04	199	76	4	180b3997174fd63bdf3b828063a13483eb4cab29
ToppCell	LPS_IL1RA-Epithelial_alveolar\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ANXA2 SEC11C GALNT5 MYO5C	3.71e-04	199	76	4	5b140ac88ebc25ce397ae577e48f3e271faf46e7
ToppCell	LPS_IL1RA_TNF-Epithelial_alveolar-AT_1\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	ANXA2 GALNT5 FGD3 MYO5C	3.71e-04	199	76	4	1c70e7d6bd25980e1b92aa1cac3f3c95d9651b4b
ToppCell	BAL-Severe-Epithelial-Epithelial-Basal/Club-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	PRSS23 GALNT5 SLC44A4 MYO5C	3.71e-04	199	76	4	a3f83fe5c3c557cd3ef8f5632f7fba5cf1859937
ToppCell	BAL-Severe-Epithelial-Epithelial-Basal/Club\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	PRSS23 GALNT5 SLC44A4 MYO5C	3.71e-04	199	76	4	644197ff7e3299587881dd678836262e670ed4a8
ToppCell	NS-moderate-d_16-33-Epithelial\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ANXA2 PRSS23 GALNT5 SLC44A4	3.71e-04	199	76	4	aa2b51940115c22768c0d7493b4b60d41df3f376
ToppCell	Severe_COVID-19-Epithelial-Basal/Club\|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）	PRSS23 GALNT5 SLC44A4 MYO5C	3.71e-04	199	76	4	2a0aebcfadff4e2dfc8244ad8a87c338ecccacfd
ToppCell	BAL-Severe-Epithelial-Epithelial-Basal/Club-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PRSS23 GALNT5 SLC44A4 MYO5C	3.71e-04	199	76	4	fd364f43859b2e7a3e91ce6a1c430cc42ad26a49
ToppCell	moderate-Epithelial-Secretory-diff\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	ANXA2 PRSS23 GALNT5 FER1L6	3.79e-04	200	76	4	6f29ef9dcf126c5c19386f6aa9a20c38a2c8ccc8
Disease	hypertension	STON1 FOLH1 INSR FGD5 SLC44A4 ENPEP TNXB	1.22e-05	307	74	7	EFO_0000537
Disease	Charcot-Marie-Tooth disease type 4H (implicated_via_orthology)	FGD1 FGD3	3.71e-05	4	74	2	DOID:0110192 (implicated_via_orthology)
Disease	X-linked Aarskog syndrome (implicated_via_orthology)	FGD1 FGD3	3.71e-05	4	74	2	DOID:6683 (implicated_via_orthology)
Disease	Photosensitive Trichothiodystrophy	ERCC2 ERCC3	3.71e-05	4	74	2	C1866504
Disease	HIV-associated neurocognitive disorder, asymptomatic neurocognitive impairment	NOMO2 IL21R	6.17e-05	5	74	2	EFO_0007948, EFO_0007983
Disease	xeroderma pigmentosum (is_implicated_in)	ERCC2 ERCC3	9.25e-05	6	74	2	DOID:0050427 (is_implicated_in)
Disease	xeroderma pigmentosum (implicated_via_orthology)	ERCC2 ERCC3	9.25e-05	6	74	2	DOID:0050427 (implicated_via_orthology)
Disease	asphyxia neonatorum (biomarker_via_orthology)	ERCC2 ERCC3	9.25e-05	6	74	2	DOID:11088 (biomarker_via_orthology)
Disease	Trichothiodystrophy Syndromes	ERCC2 ERCC3	9.25e-05	6	74	2	C1955934
Disease	Cockayne syndrome (implicated_via_orthology)	ERCC2 ERCC3	9.25e-05	6	74	2	DOID:2962 (implicated_via_orthology)
Disease	Beta blocking agent use measurement	RNMT INSR FGD5 CDC25A	1.97e-04	114	74	4	EFO_0009929
Disease	Xeroderma pigmentosum	ERCC2 ERCC3	2.21e-04	9	74	2	cv:C0043346
Disease	interleukin-36 alpha measurement	SLC44A4 TNXB	2.21e-04	9	74	2	EFO_0021851
Disease	Basal cell carcinoma	ERCC2 ERCC3	3.36e-04	11	74	2	C0007117
Disease	Antihypertensive use measurement	INSR FGD5 SRBD1 CDC25A ENPEP	5.47e-04	265	74	5	EFO_0009927
Disease	renal cell carcinoma (biomarker_via_orthology)	ANXA2 ANXA2P2	5.54e-04	14	74	2	DOID:4450 (biomarker_via_orthology)
Disease	hepatocellular carcinoma (is_marker_for)	SNW1 CSF1R ANXA2 INSR NEIL3	9.69e-04	301	74	5	DOID:684 (is_marker_for)
Disease	Down syndrome (is_marker_for)	ERCC2 ERCC3	1.39e-03	22	74	2	DOID:14250 (is_marker_for)
Disease	Malignant neoplasm of breast	TBC1D9B ERCC3 LRRC37A CSF1R LRRC37A2 FGD5 HADHB GALNT5 ENPEP	1.44e-03	1074	74	9	C0006142
Disease	Charcot-Marie-Tooth disease (implicated_via_orthology)	FGD1 FGD3	1.65e-03	24	74	2	DOID:10595 (implicated_via_orthology)
Disease	triglyceride measurement, alcohol drinking	INSR SLC44A4 KPNB1	2.00e-03	99	74	3	EFO_0004329, EFO_0004530
Disease	triglyceride measurement, alcohol consumption measurement	INSR SLC44A4 KPNB1	2.12e-03	101	74	3	EFO_0004530, EFO_0007878
Disease	hyperthyroidism (biomarker_via_orthology)	ANXA2 ANXA2P2	2.25e-03	28	74	2	DOID:7998 (biomarker_via_orthology)
Disease	Mental Retardation, X-Linked	IL1RAPL1 FGD1	2.41e-03	29	74	2	C1136249
Disease	diabetes mellitus (is_implicated_in)	CSF1R INSR	2.41e-03	29	74	2	DOID:9351 (is_implicated_in)
Disease	pappalysin‐1 measurement	FOLH1 CHST13	2.41e-03	29	74	2	EFO_0010618

Protein segments in the cluster

Peptide	Gene	Start	Entry
KPYQLKYGDMEESNL	COG7	356	P83436
YKAMKLLLLYGAELG	ANKRD23	256	Q86SG2
EENKGFYYIMKELPQ	ACADL	276	P28330
EPAAFLILLKYMYSD	BTBD6	186	Q96KE9
LNYEYLPTMGLKSFI	GOT1L1	66	Q8NHS2
EYMKAINFAKGEPRY	CFAP46	111	Q8IYW2
LLMFPYGYKCTKLDD	CPA2	311	P48052
KPLYFADRLYDSMKG	ANXA2	266	P07355
KPLYFADQLYDSMKG	ANXA2P2	266	A6NMY6
ALAMGYKPKAYLRDF	HADHB	326	P55084
LMKYIYKGFESPSDN	ARPC5	106	O15511
IVPKMVYDFLYGNKS	OR2L2	76	Q8NH16
MNPEYDYLFKLLLIG	RAB1B	1	Q9H0U4
GYFMIPLYDKGDFIL	NOMO3	76	P69849
GALQFMAYELLKLKY	SLC25A32	196	Q9H2D1
FGGLMDKKQNVKYYP	FBXO42	691	Q6P3S6
GYFMIPLYDKGDFIL	NOMO2	76	Q5JPE7
DPYLFKLPALKYLDM	LRRC37A3	981	O60309
KVRQAFLGLMPYYKD	KCTD7	151	Q96MP8
PGYAAETYLKMGDLK	IFT122	821	Q9HBG6
DPYLFKLPALKYLDM	LRRC37A2	981	A6NM11
DPYLFKLPALKYLDM	LRRC37A	981	A6NMS7
FIMINPLEYKYKNGA	NEIL3	101	Q8TAT5
GERLYDLNMPAYVKF	NCK1	101	P16333
PIGYYDAQKLLEKMG	FOLH1	296	Q04609
DMLEKHYGYKLFIPD	IL1RAPL1	436	Q9NZN1
LYEMAALQSPFYGDK	NEK7	226	Q8TDX7
MNDVLLYTYPQKDGK	FGD5	1136	Q6ZNL6
GYFMIPLYDKGDFIL	NOMO1	76	Q15155
MKLNVDGLLVYFPYD	ERCC2	1	P18074
DPYLFELPALKYLDM	LRRC37B	671	Q96QE4
KKEEYKMALYNLYPG	F8	1986	P00451
VGGAYYNLDSKLKMP	JOSD1	146	Q15040
YFAMNYSLPKLDKIA	ENPEP	336	Q07075
ILQKLAPFLKMYGEY	FGD3	236	Q5JSP0
APFLKMYGEYVKNFD	FGD3	241	Q5JSP0
DLLGFMLFYKEAPYQ	INSR	526	P06213
AEFLQKLLPGYYMNL	PIP5K1A	201	Q99755
QLKMFLDEYDDIPYK	DNAH1	3856	Q9P2D7
YKLVKDGYQMAQPAF	CSF1R	866	P07333
KQMIFTGPDYIKDYL	C4orf45	16	Q96LM5
DYLKDNLDKYMSQFP	GALNT5	541	Q7Z7M9
KGKSFILDFMLRYLY	ATL3	71	Q6DD88
GEFLKYMEAFKPFLG	KPNB1	641	Q14974
FLVYFPLLNEMAKKY	RNMT	371	O43148
ALLKDPFYMGLYQKR	ME2	211	P23368
GMGENKDKPYLLYFN	SLC44A4	76	Q53GD3
DYEDPAFYMLKGKLQ	IL21R	141	Q9HBE5
ADMYDLPKKEDALLY	EMD	71	P50402
YGAKDYRLQMPLKDD	ERCC3	56	P19447
IEQMGKFYPELKLAY	DDX19A	181	Q9NUU7
DKDFGYLILYPDMLI	DNA2	111	P51530
LNTAKKGLIDYYLMP	POLI	441	Q9UNA4
LFYKGMASYLLPGQK	FAM120B	296	Q96EK7
PELYVLKGGYKEFFM	CDC25A	461	P30304
YVRLYKAEGLPKMNS	FER1L6	246	Q2WGJ9
IIMNDYPKFKYALLA	SEC11C	166	Q9BY50
PYILPFMFYNDVKKQ	SMCHD1	1606	A6NHR9
LAEAYRLKYMFADAP	TBC1D22B	486	Q9NU19
LPSMLQDFLKEYHYK	SOCS5	506	O75159
FDMEAYLPKKNGLYL	TMEM120B	91	A0PK00
QGLFFDMEAYLPKKN	TMEM120A	91	Q9BXJ8
DMEAYLPKKNGLYLS	TMEM120A	96	Q9BXJ8
YNKFLKNGIPYMNEE	PNLDC1	111	Q8NA58
IGMDYDYALLELKKP	PRSS23	241	O95084
ILQKLAPFLKMYGEY	FGD1	456	P98174
APFLKMYGEYVKNFD	FGD1	461	P98174
AYFADLIMKNYFAPL	SRBD1	606	Q8N5C6
KQFGMPEGEKLVNYY	TBC1D9B	146	Q66K14
DLYKMDFLLFNYSAP	CHST13	321	Q8NET6
KEKRPDLYALAMGYS	THOC2	1156	Q8NI27
GLFKLRMLFKDDYPS	UBE2I	56	P63279
ILQMYYEQGLEKPFK	STON1	306	Q9Y6Q2
SPLFKYMDNDYAKLG	NAPG	256	Q99747
VPGLDPDRKYKMNLY	TNXB	1316	P22105
GLEPDHKYKMNLYGF	TNXB	2251	P22105
LEPDNKYKMNLYGFH	TNXB	2361	P22105
GLEPDHKYKMNLYGF	TNXB	2901	P22105
MNDYPKFKYAVLFLL	SEC11A	156	P67812
SIYRPSKNLDKDMYG	SNW1	446	Q13573
YKPLLSSIKNAYEGM	TSNAXIP1	91	Q2TAA8
MAFSGIYKLDDGKPY	XRRA1	1	Q6P2D8
GPKEYLGMLQYKRED	MYO5C	1356	Q9NQX4