| Category | Name | IntersectionWithQuery | PValue | GenesInTerm | GenesInQuery | GenesInTermInQuery | ID |
|---|---|---|---|---|---|---|---|
| GeneOntologyMolecularFunction | protein O-acetylglucosaminyltransferase activity | 2.40e-05 | 3 | 57 | 2 | GO:0097363 | |
| GeneOntologyMolecularFunction | glutaminase activity | 4.79e-05 | 4 | 57 | 2 | GO:0004359 | |
| GeneOntologyMolecularFunction | protein kinase activity | 2.86e-04 | 600 | 57 | 8 | GO:0004672 | |
| GeneOntologyMolecularFunction | protein serine kinase activity | 5.75e-04 | 363 | 57 | 6 | GO:0106310 | |
| GeneOntologyBiologicalProcess | peptidyl-threonine modification | 1.37e-06 | 125 | 58 | 6 | GO:0018210 | |
| GeneOntologyBiologicalProcess | peptidyl-threonine phosphorylation | 1.79e-05 | 115 | 58 | 5 | GO:0018107 | |
| GeneOntologyBiologicalProcess | glutamine catabolic process | 4.65e-05 | 4 | 58 | 2 | GO:0006543 | |
| GeneOntologyBiologicalProcess | glutamate biosynthetic process | 7.73e-05 | 5 | 58 | 2 | GO:0006537 | |
| Domain | Glutaminase | 9.48e-06 | 2 | 58 | 2 | IPR015868 | |
| Domain | Glutaminase | 9.48e-06 | 2 | 58 | 2 | PF04960 | |
| Domain | Quinoprotein_ADH-like_supfam | 2.19e-05 | 53 | 58 | 4 | IPR011047 | |
| Domain | - | 2.84e-05 | 3 | 58 | 2 | 3.40.710.10 | |
| Domain | Beta-lactam/transpept-like | 2.84e-05 | 3 | 58 | 2 | IPR012338 | |
| Domain | EGF_CA | 3.80e-05 | 122 | 58 | 5 | SM00179 | |
| Domain | EGF-like_Ca-bd_dom | 4.11e-05 | 124 | 58 | 5 | IPR001881 | |
| Domain | hEGF | 8.81e-05 | 28 | 58 | 3 | PF12661 | |
| Domain | HELP | 1.41e-04 | 6 | 58 | 2 | PF03451 | |
| Domain | HELP | 1.41e-04 | 6 | 58 | 2 | IPR005108 | |
| Domain | EGF_Ca-bd_CS | 2.34e-04 | 97 | 58 | 4 | IPR018097 | |
| Domain | EGF_CA | 2.53e-04 | 99 | 58 | 4 | PS01187 | |
| Domain | ASX_HYDROXYL | 2.63e-04 | 100 | 58 | 4 | PS00010 | |
| Domain | EGF-type_Asp/Asn_hydroxyl_site | 3.29e-04 | 106 | 58 | 4 | IPR000152 | |
| Domain | CCP | 6.30e-04 | 54 | 58 | 3 | SM00032 | |
| Domain | EGF | 6.32e-04 | 126 | 58 | 4 | PF00008 | |
| Domain | SUSHI | 7.01e-04 | 56 | 58 | 3 | PS50923 | |
| Domain | Sushi_SCR_CCP_dom | 7.38e-04 | 57 | 58 | 3 | IPR000436 | |
| Domain | Prot_kinase_dom | 7.66e-04 | 489 | 58 | 7 | IPR000719 | |
| Domain | PROTEIN_KINASE_DOM | 8.03e-04 | 493 | 58 | 7 | PS50011 | |
| Domain | EGF_3 | 8.05e-04 | 235 | 58 | 5 | PS50026 | |
| Domain | EGF | 8.05e-04 | 235 | 58 | 5 | SM00181 | |
| Domain | EGF-like_dom | 1.04e-03 | 249 | 58 | 5 | IPR000742 | |
| Domain | Pkinase | 1.15e-03 | 381 | 58 | 6 | PF00069 | |
| Domain | EGF_1 | 1.16e-03 | 255 | 58 | 5 | PS00022 | |
| Domain | WD40 | 1.24e-03 | 259 | 58 | 5 | PF00400 | |
| Domain | EGF-like_CS | 1.28e-03 | 261 | 58 | 5 | IPR013032 | |
| Domain | EGF_2 | 1.37e-03 | 265 | 58 | 5 | PS01186 | |
| Domain | Kinase-like_dom | 1.39e-03 | 542 | 58 | 7 | IPR011009 | |
| Domain | WD40 | 1.44e-03 | 268 | 58 | 5 | SM00320 | |
| Domain | WD40_repeat | 1.54e-03 | 272 | 58 | 5 | IPR001680 | |
| Domain | WD_REPEATS_1 | 1.70e-03 | 278 | 58 | 5 | PS00678 | |
| Domain | WD_REPEATS_2 | 1.72e-03 | 279 | 58 | 5 | PS50082 | |
| Domain | WD_REPEATS_REGION | 1.72e-03 | 279 | 58 | 5 | PS50294 | |
| Domain | Apc4_WD40_dom | 1.74e-03 | 20 | 58 | 2 | IPR024977 | |
| Domain | ANAPC4_WD40 | 1.74e-03 | 20 | 58 | 2 | PF12894 | |
| Domain | WD40_repeat_dom | 2.26e-03 | 297 | 58 | 5 | IPR017986 | |
| Domain | PROTEIN_KINASE_ATP | 2.93e-03 | 459 | 58 | 6 | PS00107 | |
| Domain | Bromodomain_CS | 2.94e-03 | 26 | 58 | 2 | IPR018359 | |
| Domain | - | 3.70e-03 | 333 | 58 | 5 | 2.130.10.10 | |
| Domain | WD40/YVTN_repeat-like_dom | 3.79e-03 | 335 | 58 | 5 | IPR015943 | |
| Domain | Ank_2 | 4.46e-03 | 215 | 58 | 4 | PF12796 | |
| Domain | S_TKc | 5.08e-03 | 359 | 58 | 5 | SM00220 | |
| Domain | Ank | 5.48e-03 | 228 | 58 | 4 | PF00023 | |
| Domain | BROMODOMAIN_1 | 5.89e-03 | 37 | 58 | 2 | PS00633 | |
| Domain | Pkinase_C | 5.89e-03 | 37 | 58 | 2 | IPR017892 | |
| Pubmed | An organelle-specific protein landscape identifies novel diseases and molecular mechanisms. | IVNS1ABP PTOV1 OGT EML5 MYO1E TESK2 CD2BP2 SEC16A DPYSL5 PARD3 CREBBP DDX1 | 1.84e-06 | 1321 | 59 | 12 | 27173435 |
| Pubmed | Expression of Gls and Gls2 glutaminase isoforms in astrocytes. | 2.83e-06 | 2 | 59 | 2 | 25297978 | |
| Pubmed | Molecular cloning, sequencing and expression studies of the human breast cancer cell glutaminase. | 2.83e-06 | 2 | 59 | 2 | 10620514 | |
| Pubmed | The origin and evolution of human glutaminases and their atypical C-terminal ankyrin repeats. | 2.83e-06 | 2 | 59 | 2 | 28526749 | |
| Pubmed | 2.83e-06 | 2 | 59 | 2 | 17669570 | ||
| Pubmed | 2.83e-06 | 2 | 59 | 2 | 24276018 | ||
| Pubmed | Full-length human glutaminase in complex with an allosteric inhibitor. | 2.83e-06 | 2 | 59 | 2 | 22049910 | |
| Pubmed | 2.83e-06 | 2 | 59 | 2 | 36179686 | ||
| Pubmed | Glutaminase isoforms expression switches microRNA levels and oxidative status in glioblastoma cells. | 2.83e-06 | 2 | 59 | 2 | 33610185 | |
| Pubmed | Glucose-independent glutamine metabolism via TCA cycling for proliferation and survival in B cells. | 2.83e-06 | 2 | 59 | 2 | 22225880 | |
| Pubmed | 2.83e-06 | 2 | 59 | 2 | 11130979 | ||
| Pubmed | Co-expression of glutaminase K and L isoenzymes in human tumour cells. | 2.83e-06 | 2 | 59 | 2 | 15496140 | |
| Pubmed | 5.18e-06 | 20 | 59 | 3 | 30596474 | ||
| Pubmed | 8.48e-06 | 3 | 59 | 2 | 11046145 | ||
| Pubmed | 8.48e-06 | 3 | 59 | 2 | 16254053 | ||
| Pubmed | Differential regulation of Akt/protein kinase B isoforms during cell cycle progression. | 8.48e-06 | 3 | 59 | 2 | 19166849 | |
| Pubmed | 9.15e-06 | 24 | 59 | 3 | 33722704 | ||
| Pubmed | 1.69e-05 | 4 | 59 | 2 | 27346147 | ||
| Pubmed | The C-terminus of human glutaminase L mediates association with PDZ domain-containing proteins. | 2.82e-05 | 5 | 59 | 2 | 11163757 | |
| Pubmed | The Noncanonical Role of ULK/ATG1 in ER-to-Golgi Trafficking Is Essential for Cellular Homeostasis. | 2.82e-05 | 5 | 59 | 2 | 27203176 | |
| Pubmed | 3.94e-05 | 549 | 59 | 7 | 38280479 | ||
| Pubmed | HDAC6 and Ubp-M BUZ domains recognize specific C-terminal sequences of proteins. | 4.23e-05 | 6 | 59 | 2 | 21090589 | |
| Pubmed | TET1 regulates hypoxia-induced epithelial-mesenchymal transition by acting as a co-activator. | 4.23e-05 | 6 | 59 | 2 | 25517638 | |
| Pubmed | Identification and Functional Characterization of a Novel Androgen Receptor Coregulator, EAP1. | 4.38e-05 | 40 | 59 | 3 | 34585037 | |
| Pubmed | 4.96e-05 | 118 | 59 | 4 | 30979931 | ||
| Pubmed | 5.91e-05 | 7 | 59 | 2 | 22072767 | ||
| Pubmed | The 19S proteasome positively regulates histone methylation at cytokine inducible genes. | 5.91e-05 | 7 | 59 | 2 | 19660582 | |
| Pubmed | Differential effects on p53-mediated cell cycle arrest vs. apoptosis by p90. | 5.91e-05 | 7 | 59 | 2 | 22084066 | |
| Pubmed | Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability. | 6.07e-05 | 588 | 59 | 7 | 38580884 | |
| Pubmed | 7.13e-05 | 47 | 59 | 3 | 26687681 | ||
| Pubmed | 7.87e-05 | 8 | 59 | 2 | 27934968 | ||
| Pubmed | 7.87e-05 | 8 | 59 | 2 | 37291217 | ||
| Pubmed | 9.33e-05 | 268 | 59 | 5 | 33640491 | ||
| Pubmed | A central chaperone-like role for 14-3-3 proteins in human cells. | 9.92e-05 | 861 | 59 | 8 | 36931259 | |
| Pubmed | Oxidative stress-dependent regulation of Forkhead box O4 activity by nemo-like kinase. | 1.01e-04 | 9 | 59 | 2 | 20874444 | |
| Pubmed | 1.01e-04 | 9 | 59 | 2 | 24684754 | ||
| Pubmed | Stabilization of histone demethylase PHF8 by USP7 promotes breast carcinogenesis. | 1.01e-04 | 9 | 59 | 2 | 27183383 | |
| Pubmed | 1.08e-04 | 54 | 59 | 3 | 35391932 | ||
| Pubmed | 1.54e-04 | 11 | 59 | 2 | 31730000 | ||
| Pubmed | 1.54e-04 | 11 | 59 | 2 | 24349473 | ||
| Pubmed | Bimodal regulation of the PRC2 complex by USP7 underlies tumorigenesis. | 1.54e-04 | 11 | 59 | 2 | 33849069 | |
| Pubmed | 1.54e-04 | 11 | 59 | 2 | 37279268 | ||
| Pubmed | 2.24e-04 | 69 | 59 | 3 | 32238831 | ||
| Pubmed | 2.54e-04 | 14 | 59 | 2 | 22653443 | ||
| Pubmed | MED25 is distinct from TRAP220/MED1 in cooperating with CBP for retinoid receptor activation. | 2.54e-04 | 14 | 59 | 2 | 17641689 | |
| Pubmed | Deubiquitinating enzymes: a new class of biological regulators. | 2.93e-04 | 15 | 59 | 2 | 9827704 | |
| Pubmed | Common body mass index-associated variants confer risk of extreme obesity. | 2.93e-04 | 15 | 59 | 2 | 19553259 | |
| Pubmed | A strategy for modulation of enzymes in the ubiquitin system. | 3.79e-04 | 17 | 59 | 2 | 23287719 | |
| Pubmed | PTEN counteracts FBXL2 to promote IP3R3- and Ca2+-mediated apoptosis limiting tumour growth. | 4.25e-04 | 18 | 59 | 2 | 28614300 | |
| Pubmed | Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function. | 4.33e-04 | 1353 | 59 | 9 | 29467282 | |
| Pubmed | MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons. | 4.65e-04 | 1082 | 59 | 8 | 38697112 | |
| Pubmed | 4.70e-04 | 1084 | 59 | 8 | 11544199 | ||
| Pubmed | 4.75e-04 | 89 | 59 | 3 | 36861887 | ||
| Pubmed | Acetylation-regulated interaction between p53 and SET reveals a widespread regulatory mode. | 4.75e-04 | 19 | 59 | 2 | 27626385 | |
| Pubmed | Daxx Inhibits HIV-1 Reverse Transcription and Uncoating in a SUMO-Dependent Manner. | 4.75e-04 | 19 | 59 | 2 | 32545337 | |
| Pubmed | Biochemical Reduction of the Topology of the Diverse WDR76 Protein Interactome. | 5.31e-04 | 219 | 59 | 4 | 31353912 | |
| Pubmed | 5.70e-04 | 1116 | 59 | 8 | 31753913 | ||
| Pubmed | 5.74e-04 | 95 | 59 | 3 | 29490077 | ||
| Pubmed | 8.96e-04 | 26 | 59 | 2 | 25228645 | ||
| Pubmed | ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1. | 9.18e-04 | 1201 | 59 | 8 | 35696571 | |
| Pubmed | Phosphoproteomics screen reveals akt isoform-specific signals linking RNA processing to lung cancer. | 1.04e-03 | 28 | 59 | 2 | 24462114 | |
| Pubmed | C16orf72/HAPSTR1 is a molecular rheostat in an integrated network of stress response pathways. | 1.10e-03 | 119 | 59 | 3 | 35776542 | |
| Pubmed | 1.17e-03 | 1247 | 59 | 8 | 27684187 | ||
| Pubmed | Control of a neuronal morphology program by an RNA-binding zinc finger protein, Unkempt. | 1.17e-03 | 271 | 59 | 4 | 25737280 | |
| Pubmed | 1.19e-03 | 30 | 59 | 2 | 29555813 | ||
| Pubmed | C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains. | 1.23e-03 | 1257 | 59 | 8 | 37317656 | |
| Pubmed | Genetic associations of brain structural networks in schizophrenia: a preliminary study. | 1.27e-03 | 31 | 59 | 2 | 20691427 | |
| Pubmed | 1.27e-03 | 31 | 59 | 2 | 29099309 | ||
| Pubmed | 1.27e-03 | 31 | 59 | 2 | 26678539 | ||
| Pubmed | Maternal diabetes alters transcriptional programs in the developing embryo. | 1.36e-03 | 32 | 59 | 2 | 19538749 | |
| Pubmed | 1.41e-03 | 1285 | 59 | 8 | 35914814 | ||
| Pubmed | Cdx2 regulates endo-lysosomal function and epithelial cell polarity. | 1.44e-03 | 33 | 59 | 2 | 20551175 | |
| Pubmed | Genetic mapping of the human and mouse phospholipase C genes. | 1.44e-03 | 33 | 59 | 2 | 8672127 | |
| Pubmed | 1.51e-03 | 494 | 59 | 5 | 26831064 | ||
| Pubmed | Defining the human deubiquitinating enzyme interaction landscape. | 1.52e-03 | 1005 | 59 | 7 | 19615732 | |
| Pubmed | Gfi1b regulates the level of Wnt/β-catenin signaling in hematopoietic stem cells and megakaryocytes. | 1.53e-03 | 34 | 59 | 2 | 30894540 | |
| Interaction | FOXO4 interactions | 3.03e-06 | 35 | 58 | 4 | int:FOXO4 | |
| Interaction | DYRK1A interactions | 3.51e-06 | 552 | 58 | 10 | int:DYRK1A | |
| Interaction | XAF1 interactions | 6.37e-06 | 42 | 58 | 4 | int:XAF1 | |
| Interaction | FKBP5 interactions | 2.31e-05 | 414 | 58 | 8 | int:FKBP5 | |
| Interaction | CITED4 interactions | 2.90e-05 | 21 | 58 | 3 | int:CITED4 | |
| GeneFamily | O-linked N-acetylglucosaminyltransferases|Tetratricopeptide repeat domain containing | 3.62e-05 | 4 | 45 | 2 | 446 | |
| GeneFamily | Hyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing | 3.84e-04 | 57 | 45 | 3 | 1179 | |
| GeneFamily | WD repeat domain containing | 4.68e-04 | 262 | 45 | 5 | 362 | |
| GeneFamily | Ankyrin repeat domain containing | 3.03e-03 | 242 | 45 | 4 | 403 | |
| ToppCell | droplet-Liver-HEPATOCYTES-1m-Epithelial-Hepatocyte_(Periportal)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 3.26e-06 | 175 | 58 | 5 | 5c38d4b6c03473d841e6203a7efaa6dcb2d59386 | |
| ToppCell | Control|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2 | 3.45e-06 | 177 | 58 | 5 | b8ff6940e31b749776e81ae4f5bbd577dba9749c | |
| ToppCell | renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group | 3.74e-06 | 180 | 58 | 5 | 788d5fbf688365b5d92d3aa19b9f8e9448f8be5a | |
| Disease | mean platelet volume | 3.43e-06 | 1020 | 57 | 11 | EFO_0004584 | |
| Disease | mean arterial pressure | 3.97e-04 | 499 | 57 | 6 | EFO_0006340 | |
| Disease | phosphatidylcholine 34:2 measurement | 6.81e-04 | 20 | 57 | 2 | EFO_0010376 | |
| Disease | Prostatic Neoplasms | 1.19e-03 | 616 | 57 | 6 | C0033578 | |
| Disease | Malignant neoplasm of prostate | 1.19e-03 | 616 | 57 | 6 | C0376358 | |
| Disease | chronotype measurement | 1.50e-03 | 882 | 57 | 7 | EFO_0008328 |
| Peptide | Gene | Start | Entry |
|---|---|---|---|
| CFVMEYANGGELFFH | 226 | P31751 | |
| EFYMGKFHTTCFEEG | 246 | O00555 | |
| DAGVNMYHHFCDFIN | 241 | Q5NDL2 | |
| YCGENEHGRGDFMSL | 426 | Q63HQ2 | |
| IQVMCYDYDNDGGHD | 226 | Q96FN4 | |
| CLYHFYDQMDLAGEE | 46 | P33076 | |
| MDYEEFVRGCHLGVF | 491 | P54840 | |
| DVCFFGMHVQEYGSD | 1406 | Q92793 | |
| VGAAMACALGYDIHF | 46 | Q9Y2Z9 | |
| GDEEHCFFLVEGLFM | 191 | P16066 | |
| CGAFVHGLEDEMYEV | 376 | Q96HW7 | |
| HSCGMYDFSGQFAFH | 461 | O94925 | |
| TFVQFANDECDYGMG | 276 | Q9NWY4 | |
| GTFIFCHAYLADQDM | 296 | Q5VTA0 | |
| TYEFGYQMHFICNEG | 116 | P15529 | |
| GFDGSHAISCVEMYD | 566 | Q9Y6Y0 | |
| NYGEEFTMHDTIGCY | 181 | Q92499 | |
| MLFYRNHFGAEELDG | 386 | Q9NZN1 | |
| RTDGADHGDEMYFLF | 461 | Q5XG92 | |
| YNNMFCAGFHEGGRD | 391 | P00740 | |
| YLLEGGSMAHEDFCG | 66 | O00625 | |
| CGMYDFSGQFAFHVG | 396 | Q9UI32 | |
| CMAQLYFFHFLGGTE | 96 | Q8NGN5 | |
| DCMAQIFFFHFAGGA | 96 | Q8NGJ1 | |
| SNEGFYDDMEAAGHT | 421 | Q68CR7 | |
| PGGAFYFMEHVAAEC | 166 | Q9H8H3 | |
| RIMDNGFAGCVHFSY | 341 | Q86YD1 | |
| MEEGHFDADGNYFLN | 96 | O95400 | |
| DAVQAMAFDGCYHDS | 376 | A8MPY1 | |
| GDFVHAMEGKDFNYE | 81 | Q8NHM5 | |
| TFDHGMGYFESCNIH | 461 | Q86XK2 | |
| LCMGDDLQGHYSFLG | 281 | Q5JW98 | |
| LIAHGFFSVYGMCVD | 651 | Q8IWA5 | |
| HAAGIFSMNACEEGF | 236 | Q05BV3 | |
| HSAGIFSMYACEEGF | 236 | Q6ZMW3 | |
| TLGFYDCQFNEDGSM | 341 | Q6IA86 | |
| GMFHCICDDGYELDR | 1511 | P35556 | |
| MNNFGNEEFDCHFLD | 1 | P11926 | |
| GGDFNLYENMRCHGV | 421 | Q9BPU6 | |
| GNLVEGMDFHRFYFE | 386 | Q13557 | |
| EYQAGDFEAAERHCM | 31 | O15294 | |
| FHRTFGCDDELMYGG | 1086 | Q8TEW0 | |
| DGHEVFYGIMFDAGS | 96 | O75354 | |
| ADVNECDFYGFTAFM | 116 | Q05823 | |
| FSMHVCDEVDLYGFG | 276 | Q11201 | |
| EHVCFVMEYAAGGDL | 731 | Q16513 | |
| DYGFMKEVTFHCHEG | 2906 | Q4LDE5 | |
| DTDFFCHCQAGYMGR | 676 | Q8TER0 | |
| DMDTFFLHYAAAEGQ | 61 | O75762 | |
| FNMIEGQGHGAVFDC | 506 | Q8WWQ0 | |
| LDAAHFCYLMAQAGF | 1736 | O15027 | |
| GNCYMHYGQFLLEEA | 711 | Q8N394 | |
| YECDDCGMAFGHVSQ | 151 | A6NDX5 | |
| QCFGGEYMGEVFDHM | 1921 | O00507 | |
| ACGAEDRHAYVYEMG | 771 | A2RRH5 | |
| FGLDYDAFQHMVGDC | 266 | Q96S53 | |
| AEDQFCGHQGNDMYD | 571 | Q93009 | |
| VMEYCNGGDLADYLH | 91 | O75385 | |
| GDAFHGEQMHYKCSE | 166 | P52741 | |
| HYAGKVSYDMDGFCE | 506 | Q12965 |