Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	USP37-like_PH	USP26 USP37	6.03e-06	3	27	2	IPR032069
Domain	UCH_N	USP26 USP37	6.03e-06	3	27	2	PF16674
Domain	USP_CS	USP26 USP37	4.08e-03	66	27	2	IPR018200
Domain	RNaseH-like_dom	SETMAR TOE1	4.45e-03	69	27	2	IPR012337
Domain	USP_1	USP26 USP37	4.57e-03	70	27	2	PS00972
Domain	UCH	USP26 USP37	4.70e-03	71	27	2	PF00443
Domain	USP_2	USP26 USP37	4.70e-03	71	27	2	PS00973
Domain	USP_3	USP26 USP37	4.83e-03	72	27	2	PS50235
Domain	USP_dom	USP26 USP37	4.83e-03	72	27	2	IPR028889
Domain	Peptidase_C19_UCH	USP26 USP37	4.83e-03	72	27	2	IPR001394
Domain	KRAB	ZNF132 ZNF671 ZNF566	1.45e-02	358	27	3	PS50805
Domain	KRAB	ZNF132 ZNF671 ZNF566	1.45e-02	358	27	3	PF01352
Domain	KRAB	ZNF132 ZNF671 ZNF566	1.57e-02	369	27	3	SM00349
Domain	KRAB	ZNF132 ZNF671 ZNF566	1.59e-02	370	27	3	IPR001909
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	PCF11 UBE4A TSPYL5 ZCCHC2 USP37 HERPUD1 CPEB4	1.31e-07	493	29	7	15368895
Pubmed	A de novo t(10;19)(q22.3;q13.33) leads to ZMIZ1/PRR12 reciprocal fusion transcripts in a girl with intellectual disability and neuropsychiatric alterations.	GRIN2A ZMIZ1	4.02e-06	4	29	2	26163108
Pubmed	Genome-wide SNP genotyping study using pooled DNA to identify candidate markers mediating susceptibility to end-stage renal disease attributed to Type 1 diabetes.	IRS2 ZMIZ1	1.41e-05	7	29	2	19929986
Pubmed	Self-stabilizing regulation of deubiquitinating enzymes in an enzymatic activity-dependent manner.	USP26 USP37	1.87e-05	8	29	2	33864866
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	ANKRD44 IRS2 R3HDM1 CPEB4 TNRC6A	3.12e-05	446	29	5	24255178
Pubmed	Hypoxia-induced proteasomal degradation of DBC1 by SIAH2 in breast cancer progression.	USP26 USP37	5.21e-05	13	29	2	35913115
Pubmed	Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	TSPYL5 ZCCHC2 CPEB4	8.47e-05	102	29	3	11214970
Pubmed	Putative complement control protein CSMD3 dysfunction impairs synaptogenesis and induces neurodevelopmental disorders.	GRIN2A LAMA1	1.53e-04	22	29	2	35245678
Pubmed	The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation.	ZMIZ1 R3HDM1 TNRC6A	2.75e-04	152	29	3	38360978
Pubmed	D-2-hydroxyglutarate produced by mutant IDH1 perturbs collagen maturation and basement membrane function.	HERPUD1 LAMA1	3.08e-04	31	29	2	22925884
Pubmed	An inducible CRISPR/Cas9 screen identifies DTX2 as a transcriptional regulator of human telomerase.	PCF11 R3HDM1 TNRC6A	4.51e-04	180	29	3	35198878
Pubmed	Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1.	R3HDM1 HERPUD1	5.93e-04	43	29	2	7584026
Interaction	R3HDM2 interactions	ZCCHC2 R3HDM1 CPEB4 TNRC6A	2.91e-05	129	28	4	int:R3HDM2
Interaction	DAZL interactions	ZCCHC2 R3HDM1 CPEB4 TNRC6A	4.60e-05	145	28	4	int:DAZL
GeneFamily	Ubiquitin specific peptidases	USP26 USP37	1.40e-03	56	18	2	366
Coexpression	CAFFAREL_RESPONSE_TO_THC_UP	PNISR HERPUD1 CPEB4	5.91e-06	32	29	3	M11298
ToppCell	390C-Lymphocytic-ILC-ILC-1\|ILC / Donor, Lineage, Cell class and subclass (all cells)	PCF11 VPS13A TNRC6A	4.91e-06	51	29	3	f97523d1cae5932d9a4e8d7f37c202b12e5a0685
ToppCell	10x3'2.3-week_17-19\|World / cell types per 3 fetal stages;per 3',per 5'	PCF11 IRS2 PNISR HERPUD1	7.77e-06	197	29	4	f5cfad0b42d0f817e22cc78b9bfb2b4b7e4330ed
Disease	C-reactive protein measurement	ANKRD44 CCDC168 IRS2 ZMIZ1 ZCCHC2 HERPUD1	8.00e-04	1206	28	6	EFO_0004458
Disease	non-word reading	ANKRD44 HERPUD1	1.85e-03	67	28	2	EFO_0005299
Disease	cognitive function measurement	DNAI4 GRIN2A ZCCHC2 CCDC146 CPEB4 TNRC6A	1.95e-03	1434	28	6	EFO_0008354
Disease	bipolar disorder	CDAN1 GRIN2A ZMIZ1 ZCCHC2	2.04e-03	577	28	4	MONDO_0004985
Disease	Manic Disorder	GRIN2A ZCCHC2	2.07e-03	71	28	2	C0024713
Disease	Colorectal Neoplasms	GRIN2A ZMIZ1 LAMA1	2.25e-03	277	28	3	C0009404
Disease	Manic	GRIN2A ZCCHC2	2.49e-03	78	28	2	C0338831
Disease	Depression, Bipolar	GRIN2A ZCCHC2	2.56e-03	79	28	2	C0005587
Disease	sudden cardiac arrest	GRIN2A LAMA1	2.82e-03	83	28	2	EFO_0004278
Disease	HIV-1 infection	USP26 GRIN2A	3.90e-03	98	28	2	EFO_0000180
Disease	Colorectal Carcinoma	GRIN2A ZMIZ1 LAMA1 VPS13A	4.13e-03	702	28	4	C0009402
Disease	attention deficit hyperactivity disorder, unipolar depression, bipolar disorder, autism spectrum disorder, schizophrenia	GRIN2A ZMIZ1	4.14e-03	101	28	2	EFO_0003756, EFO_0003761, EFO_0003888, MONDO_0004985, MONDO_0005090
Disease	facial width measurement	TSPYL5 GRIN2A	4.46e-03	105	28	2	EFO_0007855
Disease	eosinophil measurement	ANKRD44 ZMIZ1	4.71e-03	108	28	2	EFO_0803540

Protein segments in the cluster

Peptide	Gene	Start	Entry
GNQNHLHLTLQNNNG	USP26	66	Q9BXU7
LQAQLAQAFFHNQPP	CDAN1	846	Q8IWY9
QQPAANHIFSQDNLG	R3HDM1	531	Q15032
HNQFPAENQPANQNA	HERPUD1	216	Q15011
NGNFVIDNPQNIQAH	PLXNA1	791	Q9UIW2
NQPNNNGFTPLHFAA	ANKRD44	266	Q8N8A2
NAFNAPSQGLQFQRH	PCF11	1141	O94913
DGPNLNNNNNNNNHS	IRS2	16	Q9Y4H2
PAGSHKQQNFGLNNA	DNAI4	46	Q5VTH9
AAFNQLPHLANNLNK	CPEB4	266	Q17RY0
QDSFPGQNAFQNQGL	CCDC168	296	Q8NDH2
FQQNALSQQQAPNGH	HOXA2	251	O43364
FGLTQNSHFILPFNQ	LAMA1	2716	P25391
NNFLQGKRFHNQQDA	SETMAR	631	Q53H47
QQQFHLQQADNFPEA	CCDC146	101	Q8IYE0
NQAHQSNGNQLPFFL	ZCCHC2	1061	Q9C0B9
CGRAFNNNSNLAQHQ	ZNF132	436	P52740
DFDQHQNQPNGGKLF	ZNF671	206	Q8TAW3
FSFQPNHFFNNNKVQ	VPS13A	2246	Q96RL7
ALQAGQNHEALNNFQ	TTC24	46	A2A3L6
PLSSHQQQQLQGFSN	USP37	331	Q86T82
GKNFNYDPQLIQHQN	ZNF566	401	Q969W8
PDNRHIFNQNNHNFG	PNISR	136	Q8TF01
NNNNISSNPFAALFG	UBE4A	6	Q14139
NAFSNFPIGLNSNLN	TNRC6A	1506	Q8NDV7
LIQHGFNFNQQYAQG	TOE1	141	Q96GM8
LNSPQFAGQQQQFSA	ZMIZ1	211	Q9ULJ6
FQNHPQLASFLNSQE	TSPYL5	256	Q86VY4
QKDNLNNYVFQGQHP	GRIN2A	971	Q12879