Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncargo receptor activity

ABCA1 SCARB1 CD44 LRP1 LRP1B

3.33e-0685545GO:0038024
GeneOntologyMolecularFunctionapolipoprotein binding

ABCA1 SCARB1 LRP1

2.06e-0520543GO:0034185
GeneOntologyMolecularFunctionapolipoprotein receptor activity

ABCA1 LRP1

2.15e-053542GO:0030226
GeneOntologyMolecularFunctionlipoprotein particle receptor activity

SCARB1 LRP1 LRP1B

2.40e-0521543GO:0030228
GeneOntologyMolecularFunctionsmall GTPase binding

RANBP2 ABCA1 IPO9 PKN2 XPO1 FGD3 IQGAP1

2.41e-05321547GO:0031267
GeneOntologyMolecularFunctionGTPase binding

RANBP2 ABCA1 IPO9 PKN2 XPO1 FGD3 IQGAP1

4.99e-05360547GO:0051020
GeneOntologyMolecularFunctionATPase-coupled intramembrane lipid transporter activity

ABCA1 ABCA4 RFT1

5.84e-0528543GO:0140326
GeneOntologyMolecularFunctionapolipoprotein A-I binding

ABCA1 SCARB1

7.14e-055542GO:0034186
GeneOntologyMolecularFunctionintramembrane lipid transporter activity

ABCA1 ABCA4 RFT1

3.55e-0451543GO:0140303
GeneOntologyMolecularFunctionhigh-density lipoprotein particle binding

ABCA1 SCARB1

7.37e-0415542GO:0008035
GeneOntologyMolecularFunctionlow-density lipoprotein particle receptor activity

LRP1 LRP1B

8.41e-0416542GO:0005041
GeneOntologyMolecularFunctionfloppase activity

ABCA1 RFT1

8.41e-0416542GO:0140328
GeneOntologyMolecularFunctioncytokine receptor activity

FZD4 LIFR CD44

2.30e-0397543GO:0004896
GeneOntologyMolecularFunctionscavenger receptor activity

SCARB1 LRP1

2.41e-0327542GO:0005044
GeneOntologyMolecularFunctionamyloid-beta binding

FZD4 SCARB1 LRP1

2.66e-03102543GO:0001540
GeneOntologyMolecularFunctionnucleocytoplasmic carrier activity

IPO9 XPO1

3.38e-0332542GO:0140142
GeneOntologyMolecularFunctionlipoprotein particle binding

ABCA1 SCARB1

4.03e-0335542GO:0071813
GeneOntologyMolecularFunctionprotein-lipid complex binding

ABCA1 SCARB1

4.03e-0335542GO:0071814
GeneOntologyMolecularFunctionpattern recognition receptor activity

PGLYRP4 SCARB1

4.03e-0335542GO:0038187
GeneOntologyBiologicalProcesscell-substrate adhesion

FZD4 CD44 LRP1 UTRN PREX1 FREM1 IQGAP1 CASK

1.06e-05410548GO:0031589
GeneOntologyBiologicalProcessregulation of cell-substrate adhesion

FZD4 LRP1 UTRN PREX1 IQGAP1 CASK

5.18e-05254546GO:0010810
GeneOntologyBiologicalProcesspositive regulation of neutrophil apoptotic process

PIK3CD CD44

6.69e-055542GO:0033031
GeneOntologyBiologicalProcesscell-matrix adhesion

CD44 LRP1 UTRN FREM1 IQGAP1 CASK

7.26e-05270546GO:0007160
GeneOntologyBiologicalProcesssteroid catabolic process

STS SCARB1 CYP24A1

9.58e-0534543GO:0006706
GeneOntologyBiologicalProcessisoprenoid transport

ABCA4 SCARB1

1.00e-046542GO:0046864
GeneOntologyBiologicalProcessterpenoid transport

ABCA4 SCARB1

1.00e-046542GO:0046865
GeneOntologyBiologicalProcessnatural killer cell differentiation

PGLYRP4 PIK3CD NFIL3

1.34e-0438543GO:0001779
GeneOntologyBiologicalProcesspositive regulation of leukocyte apoptotic process

PIK3CD CD44 PERP

1.34e-0438543GO:2000108
GeneOntologyCellularComponentactin-based cell projection

SLC4A7 SCARB1 CD44 NFASC PKHD1L1 UTRN

8.80e-05278556GO:0098858
GeneOntologyCellularComponentbasolateral plasma membrane

ABCA1 SLC4A7 CD44 LRP1 IQGAP1 CASK

1.89e-04320556GO:0016323
GeneOntologyCellularComponentendocytic vesicle membrane

FZD4 ACE2 SCARB1 LRP1 MPEG1

2.36e-04212555GO:0030666
GeneOntologyCellularComponentbasal plasma membrane

ABCA1 SLC4A7 CD44 LRP1 IQGAP1 CASK

3.26e-04354556GO:0009925
GeneOntologyCellularComponentbasal part of cell

ABCA1 SLC4A7 CD44 LRP1 IQGAP1 CASK

4.61e-04378556GO:0045178
GeneOntologyCellularComponentendocytic vesicle

FZD4 ACE2 ABCA1 SCARB1 LRP1 MPEG1

5.01e-04384556GO:0030139
GeneOntologyCellularComponentannulate lamellae

RANBP2 XPO1

6.06e-0414552GO:0005642
DomainDUF5050

LRP1 LRP1B

8.83e-062562IPR032485
DomainDUF5050

LRP1 LRP1B

8.83e-062562PF16472
DomainTDE1/TMS

SERINC4 SERINC5

8.78e-055562IPR005016
DomainSerinc

SERINC4 SERINC5

8.78e-055562PF03348
DomainLDLR_class-A_CS

MALRD1 LRP1 LRP1B

2.33e-0440563IPR023415
DomainLdl_recept_a

MALRD1 LRP1 LRP1B

3.31e-0445563PF00057
Domain-

MALRD1 LRP1 LRP1B

3.54e-04465634.10.400.10
DomainLDLRA_1

MALRD1 LRP1 LRP1B

4.01e-0448563PS01209
DomainLDLRA_2

MALRD1 LRP1 LRP1B

4.27e-0449563PS50068
DomainLDrepeatLR_classA_rpt

MALRD1 LRP1 LRP1B

4.27e-0449563IPR002172
DomainLDLa

MALRD1 LRP1 LRP1B

4.27e-0449563SM00192
DomainABC_A

ABCA1 ABCA4

5.72e-0412562IPR026082
DomainPeptidase_M1

LTA4H TAF2

6.74e-0413562PF01433
DomainPeptidase_M1_N

LTA4H TAF2

6.74e-0413562IPR014782
DomainIMPORTIN_B_NT

IPO9 XPO1

7.85e-0414562PS50166
DomainLdl_recept_b

LRP1 LRP1B

7.85e-0414562PF00058
DomainLDLRB

LRP1 LRP1B

7.85e-0414562PS51120
DomainIBN_N

IPO9 XPO1

9.04e-0415562PF03810
DomainLY

LRP1 LRP1B

9.04e-0415562SM00135
DomainLDLR_classB_rpt

LRP1 LRP1B

9.04e-0415562IPR000033
DomainIBN_N

IPO9 XPO1

1.03e-0316562SM00913
DomainRhoGEF

PREX1 FGD3 FARP2

1.11e-0368563SM00325
DomainImportin-beta_N

IPO9 XPO1

1.17e-0317562IPR001494
DomainRhoGEF

PREX1 FGD3 FARP2

1.21e-0370563PF00621
DomainDH_2

PREX1 FGD3 FARP2

1.21e-0370563PS50010
DomainDH-domain

PREX1 FGD3 FARP2

1.26e-0371563IPR000219
Domain-

PREX1 FGD3 FARP2

1.26e-03715631.20.900.10
DomaincEGF

LRP1 LRP1B

2.74e-0326562IPR026823
DomaincEGF

LRP1 LRP1B

2.74e-0326562PF12662
Domain-

CD44 KLRB1 FREM1

3.08e-03975633.10.100.10
DomainC-type_lectin-like/link

CD44 KLRB1 FREM1

3.27e-0399563IPR016186
DomainARM-type_fold

IPO9 PIK3CD LTA4H TAF2 XPO1

3.42e-03339565IPR016024
DomainCTDL_fold

CD44 KLRB1 FREM1

4.07e-03107563IPR016187
DomainGDS_CDC24_CS

PREX1 FARP2

6.09e-0339562IPR001331
Domain-

LRP1 LRP1B

6.09e-03395622.120.10.30
DomainEGF

MALRD1 LRP1 LRP1B

6.41e-03126563PF00008
DomainABC_transporter_CS

ABCA1 ABCA4

7.04e-0342562IPR017871
DomainEGF_1

LAMB4 MALRD1 LRP1 LRP1B

7.15e-03255564PS00022
DomainEGF-like_CS

LAMB4 MALRD1 LRP1 LRP1B

7.75e-03261564IPR013032
DomainEGF_2

LAMB4 MALRD1 LRP1 LRP1B

8.17e-03265564PS01186
Domain6-blade_b-propeller_TolB-like

LRP1 LRP1B

8.40e-0346562IPR011042
DomainWW

UTRN IQGAP1

8.75e-0347562PF00397
DomainWW

UTRN IQGAP1

9.12e-0348562SM00456
PathwayWP_STATIN_PATHWAY

ABCA1 SCARB1 LRP1

2.65e-0519443MM15868
Pubmed

Naturally Occurring Variants in LRP1 (Low-Density Lipoprotein Receptor-Related Protein 1) Affect HDL (High-Density Lipoprotein) Metabolism Through ABCA1 (ATP-Binding Cassette A1) and SR-B1 (Scavenger Receptor Class B Type 1) in Humans.

ABCA1 SCARB1 LRP1

4.17e-09357329853565
Pubmed

Stage-specific association of apolipoprotein A-I and E in developing mouse retina.

ABCA1 SCARB1 LRP1

1.50e-061457317389516
Pubmed

Striking differences of LDL receptor-related protein 1B expression in mouse and human.

LRP1 LRP1B

2.64e-06257215963947
Pubmed

Impact of android overweight or obesity and insulin resistance on basal and postprandial SR-BI and ABCA1-mediated serum cholesterol efflux capacities.

ABCA1 SCARB1

2.64e-06257219837407
Pubmed

Trans-intestinal cholesterol efflux is not mediated through high density lipoprotein.

ABCA1 SCARB1

2.64e-06257222802462
Pubmed

HDL-scavenger receptor B type 1 facilitates SARS-CoV-2 entry.

ACE2 SCARB1

2.64e-06257233244168
Pubmed

15-Lipoxygenase-mediated modification of high-density lipoproteins impairs SR-BI- and ABCA1-dependent cholesterol efflux from macrophages.

ABCA1 SCARB1

2.64e-06257216647293
Pubmed

Hypocholesterolemia, foam cell accumulation, but no atherosclerosis in mice lacking ABC-transporter A1 and scavenger receptor BI.

ABCA1 SCARB1

2.64e-06257221840001
Pubmed

Host HDL biogenesis machinery is recruited to the inclusion of Chlamydia trachomatis-infected cells and regulates chlamydial growth.

ABCA1 SCARB1

2.64e-06257222672264
Pubmed

Pharmacologic suppression of hepatic ATP-binding cassette transporter 1 activity in mice reduces high-density lipoprotein cholesterol levels but promotes reverse cholesterol transport.

ABCA1 SCARB1

2.64e-06257221859969
Pubmed

Impairment of the ABCA1 and SR-BI-mediated cholesterol efflux pathways and HDL anti-inflammatory activity in Alzheimer's disease.

ABCA1 SCARB1

2.64e-06257222178419
Pubmed

Cross-inhibition of SR-BI- and ABCA1-mediated cholesterol transport by the small molecules BLT-4 and glyburide.

ABCA1 SCARB1

2.64e-06257215102890
Pubmed

LRP-1--CD44, a new cell surface complex regulating tumor cell adhesion.

CD44 LRP1

2.64e-06257222711991
Pubmed

The polyphenol PGG enhances expression of SR-BI and ABCA1 in J774 and THP-1 macrophages.

ABCA1 SCARB1

2.64e-06257226322417
Pubmed

Relative contributions of ABCA1 and SR-BI to cholesterol efflux to serum from fibroblasts and macrophages.

ABCA1 SCARB1

2.64e-06257216410457
Pubmed

Importin-β and CRM1 control a RANBP2 spatiotemporal switch essential for mitotic kinetochore function.

RANBP2 XPO1

2.64e-06257228600321
Pubmed

Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma.

SLC4A7 SCARB1 CD44 PKN2 UTRN IQGAP1 CASK

2.76e-0637757738117590
Pubmed

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.

RANBP2 IPO9 SLC4A7 FADS3 SCARB1 CD44 LRP1 NFASC TAF2 XPO1 PRAME

3.47e-061203571129180619
Pubmed

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.

ACE2 SLC4A7 SCARB1 CD44 PKN2 TAF2 CASK FARP2

3.99e-0656957830639242
Pubmed

Trans-ancestry analysis reveals genetic and nongenetic associations with COVID-19 susceptibility and severity.

RANBP2 MALRD1 NFASC

4.66e-062057333888907
Pubmed

A year of COVID-19 GWAS results from the GRASP portal reveals potential genetic risk factors.

RANBP2 MALRD1 NFASC

4.66e-062057335224516
Pubmed

High-density lipoprotein-mediated transcellular cholesterol transport in mouse aortic endothelial cells.

ABCA1 SCARB1

7.91e-06357226255968
Pubmed

Cellular physiology of cholesterol efflux in vascular endothelial cells.

ABCA1 SCARB1

7.91e-06357215492319
Pubmed

Cellular cholesterol transport proteins in diabetic nephropathy.

ABCA1 SCARB1

7.91e-06357225181357
Pubmed

Macrophage ABCA1 and ABCG1, but not SR-BI, promote macrophage reverse cholesterol transport in vivo.

ABCA1 SCARB1

7.91e-06357217657311
Pubmed

ApoA-I induces S1P release from endothelial cells through ABCA1 and SR-BI in a positive feedback manner.

ABCA1 SCARB1

7.91e-06357227377933
Pubmed

Hepatic Overexpression of Endothelial Lipase Lowers High-Density Lipoprotein but Maintains Reverse Cholesterol Transport in Mice: Role of Scavenger Receptor Class B Type I/ATP-Binding Cassette Transporter A1-Dependent Pathways.

ABCA1 SCARB1

7.91e-06357229748333
Pubmed

Cellular SR-BI and ABCA1-mediated cholesterol efflux are gender-specific in healthy subjects.

ABCA1 SCARB1

7.91e-06357218057374
Pubmed

The transcription levels of ABCA1, ABCG1 and SR-BI are negatively associated with plasma CRP in Chinese populations with various risk factors for atherosclerosis.

ABCA1 SCARB1

7.91e-06357222614118
Pubmed

Patient Mutation Directed shRNA Screen Uncovers Novel Bladder Tumor Growth Suppressors.

SAMD9L IQGAP1

7.91e-06357226078295
Pubmed

Role of plasma and liver cholesterol- and lipoprotein-metabolism determinants in LpX formation in the mouse.

ABCA1 SCARB1

7.91e-06357217399905
Pubmed

ABCA1, ABCG1 and SR-BI: hormonal regulation in primary rat hepatocytes and human cell lines.

ABCA1 SCARB1

7.91e-06357217241464
Pubmed

Lipoprotein (a) upregulates ABCA1 in liver cells via scavenger receptor-B1 through its oxidized phospholipids.

ABCA1 SCARB1

7.91e-06357225852127
Pubmed

Apolipoprotein A-I but not high-density lipoproteins are internalised by RAW macrophages: roles of ATP-binding cassette transporter A1 and scavenger receptor BI.

ABCA1 SCARB1

7.91e-06357217906976
Pubmed

Effect of bariatric surgery-induced weight loss on SR-BI-, ABCG1-, and ABCA1-mediated cellular cholesterol efflux in obese women.

ABCA1 SCARB1

7.91e-06357221289254
Pubmed

Determinants of leukocyte adenosine triphosphate-binding cassette transporter G1 gene expression in type 2 diabetes mellitus.

ABCA1 SCARB1

7.91e-06357218640393
Pubmed

The roles of different pathways in the release of cholesterol from macrophages.

ABCA1 SCARB1

7.91e-06357217761631
Pubmed

Pathways by which reconstituted high-density lipoprotein mobilizes free cholesterol from whole body and from macrophages.

ABCA1 SCARB1

7.91e-06357220018934
Pubmed

Differential phospholipid substrates and directional transport by ATP-binding cassette proteins ABCA1, ABCA7, and ABCA4 and disease-causing mutants.

ABCA1 ABCA4

7.91e-06357224097981
Pubmed

Enhanced foam cell formation, atherosclerotic lesion development, and inflammation by combined deletion of ABCA1 and SR-BI in Bone marrow-derived cells in LDL receptor knockout mice on western-type diet.

ABCA1 SCARB1

7.91e-06357221071707
Pubmed

Nascent HDL formation in hepatocytes and role of ABCA1, ABCG1, and SR-BI.

ABCA1 SCARB1

7.91e-06357222190590
Pubmed

Rutaecarpine suppresses atherosclerosis in ApoE-/- mice through upregulating ABCA1 and SR-BI within RCT.

ABCA1 SCARB1

7.91e-06357224908654
Pubmed

ApoE promotes hepatic selective uptake but not RCT due to increased ABCA1-mediated cholesterol efflux to plasma.

ABCA1 SCARB1

7.91e-06357222383685
Pubmed

Analysis of lipid pathway genes indicates association of sequence variation near SREBF1/TOM1L2/ATPAF2 with dementia risk.

ABCA1 SCARB1 LRP1

1.48e-052957320167577
Pubmed

MCP-1 impacts RCT by repressing ABCA1, ABCG1, and SR-BI through PI3K/Akt posttranslational regulation in HepG2 cells.

ABCA1 SCARB1

1.58e-05457223402987
Pubmed

TRIM25 enhances cell growth and cell survival by modulating p53 signals via interaction with G3BP2 in prostate cancer.

RANBP2 TRIM25

1.58e-05457229379164
Pubmed

Gene-gene combination effect and interactions among ABCA1, APOA1, SR-B1, and CETP polymorphisms for serum high-density lipoprotein-cholesterol in the Japanese population.

ABCA1 SCARB1

1.58e-05457224376512
Pubmed

Hormone-sensitive lipase deficiency affects the expression of SR-BI, LDLr, and ABCA1 receptors/transporters involved in cellular cholesterol uptake and efflux and disturbs fertility in mouse testis.

ABCA1 SCARB1

1.58e-05457234461308
Pubmed

Depletion of pre-beta-high density lipoprotein by human chymase impairs ATP-binding cassette transporter A1- but not scavenger receptor class B type I-mediated lipid efflux to high density lipoprotein.

ABCA1 SCARB1

1.58e-05457214701812
Pubmed

Localisation and regulation of cholesterol transporters in the human hair follicle: mapping changes across the hair cycle.

ABCA1 SCARB1

1.58e-05457233404706
Pubmed

LRP1 controls cPLA2 phosphorylation, ABCA1 expression and cellular cholesterol export.

ABCA1 LRP1

1.58e-05457219718435
Pubmed

ATP-binding cassette transporters G1 and G4 mediate cellular cholesterol efflux to high-density lipoproteins.

ABCA1 SCARB1

1.58e-05457215210959
Pubmed

Characterization of placental cholesterol transport: ABCA1 is a potential target for in utero therapy of Smith-Lemli-Opitz syndrome.

ABCA1 SCARB1

1.58e-05457218775956
Pubmed

[Influence of genetic combinations on HDL-C levels in a Southern Brazilian population].

ABCA1 SCARB1

1.58e-05457220835684
Pubmed

CRM1 controls the composition of nucleoplasmic pre-snoRNA complexes to licence them for nucleolar transport.

XPO1 TGS1

1.58e-05457221522132
Pubmed

Liver X receptors and oxysterols promote ventral midbrain neurogenesis in vivo and in human embryonic stem cells.

ABCA1 SCARB1 LRP1

1.82e-053157319796621
Pubmed

Cholesteryl ester transfer protein (CETP) expression enhances HDL cholesteryl ester liver delivery, which is independent of scavenger receptor BI, LDL receptor related protein and possibly LDL receptor.

SCARB1 LRP1

2.63e-05557217055779
Pubmed

The impact of severe LDL receptor mutations on SREBP-pathway regulation in homozygous familial hypercholesterolemia (FH).

ABCA1 SCARB1

2.63e-05557222425645
Pubmed

Association of the 3' UTR transcription factor LBP-1c/CP2/LSF polymorphism with late-onset Alzheimer's disease.

SCARB1 LRP1

2.63e-05557212555245
Pubmed

Oxidative stress inhibits nuclear protein export by multiple mechanisms that target FG nucleoporins and Crm1.

RANBP2 XPO1

2.63e-05557219828735
Pubmed

TGF-beta1 up-regulates expression of ABCA1, ABCG1 and SR-BI through liver X receptor alpha signaling pathway in THP-1 macrophage-derived foam cells.

ABCA1 SCARB1

2.63e-05557220057170
Pubmed

PAPP-A negatively regulates ABCA1, ABCG1 and SR-B1 expression by inhibiting LXRα through the IGF-I-mediated signaling pathway.

ABCA1 SCARB1

2.63e-05557222503545
Pubmed

Posttranscriptional regulation of retroviral gene expression: primary RNA transcripts play three roles as pre-mRNA, mRNA, and genomic RNA.

XPO1 TGS1

2.63e-05557223754689
Pubmed

Propofol up-regulates expression of ABCA1, ABCG1, and SR-B1 through the PPARγ/LXRα signaling pathway in THP-1 macrophage-derived foam cells.

ABCA1 SCARB1

2.63e-05557225600616
Pubmed

Apolipoprotein CI inhibits scavenger receptor BI and increases plasma HDL levels in vivo.

SCARB1 LRP1

2.63e-05557218992221
Pubmed

Scavenger receptor class B type I (SR-BI) mediates adhesion of neonatal murine microglia to fibrillar beta-amyloid.

SCARB1 LRP1

2.63e-05557211240025
Pubmed

Genome-scale RNAi screen for host factors required for HIV replication.

FZD4 SLC4A7 PERP EVI2A PKN2 XPO1

2.79e-0536157618976975
Pubmed

Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.

RANBP2 SLC4A7 TRIM25 FADS3 SCARB1 CD44 RFT1

3.89e-0556857737774976
Pubmed

Association of polymorphisms in genes involved in lipoprotein metabolism with plasma concentrations of remnant lipoproteins and HDL subpopulations before and after hormone therapy in postmenopausal women.

ABCA1 SCARB1

3.94e-05657219489872
Pubmed

Membrane Cholesterol Efflux Drives Tumor-Associated Macrophage Reprogramming and Tumor Progression.

ABCA1 PIK3CD

3.94e-05657230930171
Pubmed

Somatic gene therapy for dyslipidemias.

SCARB1 LRP1

3.94e-05657210482304
Pubmed

Hyaluronan-CD44 interaction with IQGAP1 promotes Cdc42 and ERK signaling, leading to actin binding, Elk-1/estrogen receptor transcriptional activation, and ovarian cancer progression.

CD44 IQGAP1

3.94e-05657215655247
Pubmed

Different cellular traffic of LDL-cholesterol and acetylated LDL-cholesterol leads to distinct reverse cholesterol transport pathways.

ABCA1 SCARB1

3.94e-05657217148552
Pubmed

Phosphorylation of Crm1 by CDK1-cyclin-B promotes Ran-dependent mitotic spindle assembly.

RANBP2 XPO1

3.94e-05657223729730
Pubmed

The carboxyterminus of the ATP-binding cassette transporter A1 interacts with a beta2-syntrophin/utrophin complex.

ABCA1 UTRN

5.51e-05757212054535
Pubmed

Ontogenesis and regulation of cholesterol metabolism in the central nervous system of the mouse.

ABCA1 SCARB1

5.51e-05757214643015
Pubmed

Linkage analysis of variations in CD4:CD8 T cell subsets between C57BL/6 and DBA/2.

CD44 KLRB1

5.51e-05757212070778
Pubmed

Endosomal transport of ErbB-2: mechanism for nuclear entry of the cell surface receptor.

RANBP2 XPO1

5.51e-05757216314522
Pubmed

Cell Surface Proteomic Map of HIV Infection Reveals Antagonism of Amino Acid Metabolism by Vpu and Nef.

SLC4A7 SCARB1 CD44 SERINC5

6.70e-0513257426439863
Pubmed

Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice.

CD44 KLRB1

7.34e-05857210704459
Pubmed

Common variants of multiple genes that control reverse cholesterol transport together explain only a minor part of the variation of HDL cholesterol levels.

ABCA1 SCARB1

7.34e-05857216542392
Pubmed

Network organization of the human autophagy system.

YLPM1 LTA4H XPO1 UTRN FREM1 IQGAP1

8.03e-0543757620562859
Pubmed

Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.

RANBP2 NFIL3 ANKRD11 XPO1 IQGAP1

8.47e-0527257531010829
Pubmed

Successful elimination of memory-type CD8+ T cell subsets by the administration of anti-Gr-1 monoclonal antibody in vivo.

CD44 KLRB1

9.43e-05957214609575
Pubmed

Several lipid-related gene polymorphisms interact with overweight/obesity to modulate blood pressure levels.

ABCA1 SCARB1

9.43e-05957223109900
Pubmed

Assembly and maturation of the U3 snoRNP in the nucleoplasm in a large dynamic multiprotein complex.

XPO1 TGS1

9.43e-05957215574333
Pubmed

Cutting edge: Toll-like receptor signaling in macrophages induces ligands for the NKG2D receptor.

CD44 KLRB1

9.43e-05957214764662
Pubmed

Rev-ing up post-transcriptional HIV-1 RNA expression.

XPO1 TGS1

9.43e-05957221358275
Pubmed

The zinc finger cluster domain of RanBP2 is a specific docking site for the nuclear export factor, exportin-1.

RANBP2 XPO1

9.43e-05957210601307
Pubmed

Biological, clinical and population relevance of 95 loci for blood lipids.

ABCA1 FADS3 SCARB1 LRP1

9.90e-0514657420686565
Pubmed

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation.

CD44 LRP1 NFASC IQGAP1 CASK

1.05e-0428557521423176
Pubmed

Cholesterol efflux pathways hinder KRAS-driven lung tumor progenitor cell expansion.

ABCA1 SCARB1

1.18e-041057237267915
Pubmed

Association of extreme blood lipid profile phenotypic variation with 11 reverse cholesterol transport genes and 10 non-genetic cardiovascular disease risk factors.

ABCA1 SCARB1

1.18e-041057212966036
Pubmed

The RanBP2/RanGAP1*SUMO1/Ubc9 SUMO E3 ligase is a disassembly machine for Crm1-dependent nuclear export complexes.

RANBP2 XPO1

1.18e-041057227160050
Pubmed

GATA-3 is required for early T lineage progenitor development.

CD44 KLRB1

1.18e-041057219934022
Pubmed

Concordant association of lipid gene variation with a combined HDL/LDL-cholesterol phenotype in two European populations.

ABCA1 SCARB1

1.18e-041057216770077
Pubmed

AMPK, a Regulator of Metabolism and Autophagy, Is Activated by Lysosomal Damage via a Novel Galectin-Directed Ubiquitin Signal Transduction System.

RANBP2 SLC4A7 TRIM25 XPO1 IQGAP1 CASK

1.40e-0448457631995728
Pubmed

LRP2 mediates folate uptake in the developing neural tube.

LRP1 LRP1B

1.44e-041157224639464
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

RANBP2 SLC4A7 TRIM25 ANKRD11 TAF2 UTRN PREX1 IQGAP1 CASK FARP2

1.44e-041497571031527615
Pubmed

CD1d1 mutant mice are deficient in natural T cells that promptly produce IL-4.

CD44 KLRB1

1.72e-04125729133426
InteractionPDZK1 interactions

ACE2 ABCA1 SLC4A7 SCARB1 FARP2

9.90e-0766555int:PDZK1
InteractionITGB1BP1 interactions

TRIM25 LRP1 XPO1 UTRN

1.92e-0633554int:ITGB1BP1
InteractionSNORD3A interactions

TRIM25 XPO1 TGS1

5.40e-0613553int:SNORD3A
InteractionWNT7B interactions

FZD4 TRIM25 CASK

1.27e-0517553int:WNT7B
InteractionPDPK1 interactions

ACE2 CD44 PKN2 XPO1 UTRN IQGAP1

1.86e-05203556int:PDPK1
InteractionC11orf52 interactions

SLC4A7 SCARB1 XPO1 UTRN IQGAP1 CASK FARP2

2.10e-05311557int:C11orf52
InteractionCTNNAL1 interactions

TRIM25 EVI2A UTRN CASK

2.97e-0565554int:CTNNAL1
InteractionDAB2 interactions

ACE2 YLPM1 LRP1 XPO1 IQGAP1

3.96e-05140555int:DAB2
InteractionCDC42 interactions

ABCA1 IPO9 SLC4A7 FADS3 SCARB1 CD44 PKN2 XPO1 UTRN PREX1 FGD3 IQGAP1 CASK

4.29e-0513235513int:CDC42
InteractionKCMF1 interactions

ACE2 TRIM25 SERINC5 XPO1 CDRT15P3

7.26e-05159555int:KCMF1
InteractionRHOF interactions

SLC4A7 TRIM25 SCARB1 CD44 PKN2 XPO1 UTRN IQGAP1 CASK

7.87e-05673559int:RHOF
InteractionMISP interactions

TRIM25 RUSC1 ERLEC1 IQGAP1 FARP2

8.41e-05164555int:MISP
Cytoband6q24

PERP UTRN

4.22e-0585726q24
GeneFamilyLow density lipoprotein receptors

LRP1 LRP1B

3.48e-0413392634
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

PREX1 FGD3 FARP2

3.87e-0466393722
GeneFamilyATP binding cassette subfamily A

ABCA1 ABCA4

4.06e-0414392805
GeneFamilyADAM metallopeptidase domain containing|CD molecules

FZD4 LIFR CD44 LRP1 KLRB1

1.50e-03394395471
GeneFamilyFibronectin type III domain containing

LIFR EPHA6 NFASC

4.92e-03160393555
CoexpressionGSE29618_MONOCYTE_VS_MDC_UP

ABCA1 STS CD44 LRP1 EVI2A LTA4H

4.33e-06200566M4948
CoexpressionBUSSLINGER_GASTRIC_IMMUNE_CELLS

RANBP2 SAMD9L SLC4A7 PIK3CD CD44 ANKRD11 EVI2A XPO1 UTRN PREX1 KLRB1 FGD3 IQGAP1

1.19e-0514925613M40023
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HOPC

SCARB1 LRP1 EVI2A SERINC5 GRM5 PREX1 CASK

1.26e-05366567M39052
CoexpressionPATEL_SKIN_OF_BODY_ZOSTAVAX_AGE_70_93YO_VZV_CHALLENGE_6HR_UP

LIFR ABCA1 SLC4A7 NFIL3 CD44 TAF2

3.62e-05291566M41002
CoexpressionONKEN_UVEAL_MELANOMA_UP

IPO9 FADS3 STS NFIL3 LRP1 SERINC5 TAF2 IQGAP1 TGS1

4.18e-05790569M12490
CoexpressionGSE28130_ACTIVATED_VS_INDUCEED_TREG_UP

RANBP2 SLC4A7 NFIL3 EVI2A CASK

6.38e-05197565M8343
CoexpressionGSE3982_BCELL_VS_NKCELL_DN

LIFR CYP24A1 RUSC1 LRP1B KLRB1

6.38e-05197565M5548
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HRGL2C

LIFR CD44 LRP1 GRM5 LRP1B PREX1

6.69e-05325566M39053
CoexpressionGSE28783_ANTI_MIR33_VS_UNTREATED_ATHEROSCLEROSIS_MACROPHAGE_DN

TRIM25 NFIL3 GRM5 KLRB1 CASK

6.69e-05199565M8352
CoexpressionGSE5589_LPS_VS_LPS_AND_IL6_STIM_IL6_KO_MACROPHAGE_45MIN_DN

SAMD9L TRIM25 SCARB1 UTRN IQGAP1

6.85e-05200565M6621
CoexpressionGSE5679_PPARG_LIGAND_ROSIGLITAZONE_VS_RARA_AGONIST_AM580_TREATED_DC_DN

SAMD9L SLC4A7 PIK3CD UTRN FGD3

6.85e-05200565M6563
CoexpressionGSE37301_COMMON_LYMPHOID_PROGENITOR_VS_CD4_TCELL_UP

RANBP2 NFIL3 CD44 SERINC5 TGS1

6.85e-05200565M8868
CoexpressionGOLDRATH_ANTIGEN_RESPONSE

SLC4A7 NFIL3 CD44 PERP EVI2A KLRB1

1.28e-04366566M11884
ToppCelldroplet-Lung-1m-Hematologic-myeloid|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NFIL3 CD44 LRP1 MPEG1 EVI2A IQGAP1

1.12e-071795766d2458a887047b5c20389f08345ff5aac7c683e6
ToppCelldroplet-Limb_Muscle-MUSCLE|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RANBP2 SAMD9L SCARB1 ANKRD11 PKN2 UTRN

1.80e-07194576e3d63874111d1e8da3977329426e4dcf68d6de87
ToppCell(0)_Myeloid-(000)_CD14+_Monocyte|(0)_Myeloid / immune cells in Peripheral Blood (logTPM normalization)

NFIL3 CD44 LRP1 MPEG1 EVI2A XPO1

1.91e-07196576e9718642ee2751c9d46a1b968547bdcb59cdfd30
ToppCellcontrol-Myeloid-Non-resident_Macrophage|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

NFIL3 CD44 LRP1 LTA4H SERINC5 IQGAP1

1.97e-07197576df2fe36cb96e2565a9d21c24cb4e451e8befd4be
ToppCellBL|World / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SAMD9L NFIL3 CD44 EVI2A PREX1 IQGAP1

1.97e-071975761acf0191fa0a25cd20bfd9ea7bf727a1555986a1
ToppCellCOVID-19_Convalescent-Classical_Monocyte-cMono_2|COVID-19_Convalescent / Disease condition and Cell class

CD44 LRP1 MPEG1 EVI2A LTA4H IQGAP1

2.03e-07198576f65fd9b773aeafa55e38309479954a8e41371f52
ToppCellCOVID-19-lung|COVID-19 / Disease (COVID-19 only), tissue and cell type

ABCA1 SAMD9L CD44 LRP1 LTA4H UTRN

2.09e-07199576155b03b859157013e9142e9248551369127d9204
ToppCellSepsis-ICU-SEP-Myeloid-CD14+_Monocyte|ICU-SEP / Disease, condition lineage and cell class

CD44 LRP1 MPEG1 EVI2A LTA4H IQGAP1

2.15e-0720057692c30e78c0e952bf4790f268d1a5facf3891682d
ToppCellfacs-MAT-Fat-3m-Myeloid-macrophage|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIM25 CD44 MPEG1 EVI2A PREX1

2.17e-06164575b81498c3934e0d52bf0329dc745e02966f9d8613
ToppCellfacs-MAT-Fat-18m-Myeloid-macrophage|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIM25 CD44 MPEG1 EVI2A PREX1

2.38e-06167575c2952d8ba763374c5678b92825c8956fc3e3ecd2
ToppCellSigmoid-Macrophage-Macrophage|Macrophage / Region, Cell class and subclass

ABCA1 SCARB1 MPEG1 EVI2A UTRN

2.45e-06168575bb16e135b6ae0d66615420b61edd6f62f2a3233c
ToppCellfacs-Lung-24m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NFIL3 CD44 LRP1 MPEG1 EVI2A

2.52e-06169575907e4c7d0df6dd46664d69834251aebca8e1dd1e
ToppCellfacs-GAT-Fat-3m-Myeloid-nan|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIM25 CD44 MPEG1 EVI2A PREX1

2.67e-061715753f796d53d3110e5d6e97de53bb49d323944659d6
ToppCellfacs-GAT-Fat-3m-Myeloid-myeloid_cell|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIM25 CD44 MPEG1 EVI2A PREX1

2.67e-06171575d9fbc2b00dbf9dddc95d9a20d804459a9ebd1820
ToppCellfacs-GAT-Fat-3m-Myeloid|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIM25 CD44 MPEG1 EVI2A PREX1

2.67e-06171575e77bfc925d73ccffe3c8cfb13764e70579a7f942
ToppCelldroplet-Lung-21m-Hematologic-myeloid|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NFIL3 CD44 LRP1 MPEG1 EVI2A

2.67e-0617157522ad6de44e1d3f72a3d78d46fd26a5743a4f84a5
ToppCellfacs-Lung-24m-Hematologic-myeloid-classical_monocyte|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NFIL3 CD44 LRP1 MPEG1 EVI2A

2.75e-06172575f557ec1b4d08b42559da02dd1f2387283c6380a2
ToppCellImmune_cells-Monocytes|Immune_cells / Lineage and Cell class

NFIL3 SCARB1 LRP1 MPEG1 EVI2A

2.83e-061735753eced40a65453a023a1673658592e7e2a099119b
ToppCell3'-GW_trimst-1.5-SmallIntestine-Hematopoietic-T_cells-ILCP|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC4A7 CYP24A1 EVI2A PREX1 KLRB1

2.99e-06175575f2c3e0f728a43d6988e793c8a50c964f7447db82
ToppCelldroplet-Limb_Muscle-MUSCLE-30m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RANBP2 SAMD9L ANKRD11 PKN2 UTRN

3.25e-0617857501dafd19de04eff459253eaa9a35debf8f3deedf
ToppCelldroplet-Lung-21m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TRIM25 CD44 PERP LRP1 MPEG1

3.82e-0618457515ea746c77785120f69f9ab370fb7eb9b70692f8
ToppCelldroplet-Marrow-nan-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SAMD9L ANKRD11 MPEG1 UTRN IQGAP1

3.82e-061845751154a5ad7b8512272b7476f949ddac350910bfb7
ToppCelldroplet-Lung-21m-Hematologic-myeloid-alveolar_macrophage|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TRIM25 CD44 PERP LRP1 MPEG1

3.82e-06184575bd5e8fc453a6393b8778734a2c3c2f1281769bcd
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LAMB4 SLC4A7 EPHA6 CD44 LRP1B

4.35e-06189575e059be2965cca70ff5576df055d0af1775b76e00
ToppCellControl-T_cells-CD4+_T_cells|Control / group, cell type (main and fine annotations)

SLC4A7 PIK3CD PREX1 FGD3 CASK

4.46e-061905750733be5e54fe15d6d6ea51c154a95258e83f1b92
ToppCell10x3'2.3-week_17-19-Lymphocytic_B-B_lineage-pro_B_progenitor|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

SCARB1 PKN2 SERINC5 XPO1 UTRN

4.58e-0619157540813c397f533c2f4a6359a77757f736b6d9e07d
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_T/NK|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PIK3CD CD44 PREX1 KLRB1 FGD3

4.58e-0619157596a7179a845d3daa046ed71fa45c51255f130a7f
ToppCellMyeloid-Myeloid-B_(Activated_Macrophage)|Myeloid / shred on cell class and cell subclass (v4)

RANBP2 CD44 LRP1 MPEG1 IQGAP1

4.58e-061915757bf125249af1e8bb138ed4d999fdd74b03ab2447
ToppCellChildren_(3_yrs)-Immune-T_lymphocyte|Children_(3_yrs) / Lineage, Cell type, age group and donor

SLC4A7 PIK3CD KLRB1 FGD3 CASK

4.82e-06193575b9769b45125d2244afe53f9f71c92c04ddccf980
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA1 PIK3CD LRP1 MPEG1 PREX1

4.94e-061945751dce6d4b6ac41f80677e3e4c335a4f383bd76f85
ToppCellControl-Classical_Monocyte-cMono_2|Control / Disease condition and Cell class

CD44 LRP1 MPEG1 EVI2A IQGAP1

5.07e-061955750fea64ee3eedf3929abb0dd9c5f5fc72f181eed9
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA1 PIK3CD LRP1 MPEG1 PREX1

5.07e-0619557534a9462f4e843f3065cc58c17ad71c1b5b836ae1
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic-Neutrophil|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TRIM25 NFIL3 CD44 EVI2A PREX1

5.19e-06196575fe8d3f45a64323947c36b127355d5940eb56c0ca
ToppCellCOVID-19_Mild-Classical_Monocyte-cMono_3|COVID-19_Mild / Disease condition and Cell class

NFIL3 LRP1 MPEG1 LTA4H IQGAP1

5.19e-06196575f245e929a286cb097130572e1027b4f01be8b04d
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Myeloid-Monocytic-Classical_Monocyte-Mono_c2-CD14-HLA-DPB1|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CD44 LRP1 MPEG1 EVI2A LTA4H

5.19e-061965755bcb57c57d5da0440220a1133a96aa89407bd871
ToppCellInt-URO-Myeloid-CD14_Mono|Int-URO / Disease, Lineage and Cell Type

CD44 LRP1 MPEG1 LTA4H IQGAP1

5.19e-06196575e6a897c29404119fb40c29033d0198a866015bf8
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TRIM25 NFIL3 CD44 EVI2A PREX1

5.19e-06196575526d037bb12d81f1c235c60ddc787fbad0bbad77
ToppCellURO-Myeloid-CD14_Mono|URO / Disease, Lineage and Cell Type

CD44 LRP1 MPEG1 LTA4H IQGAP1

5.32e-0619757545c16125fa32e50304fdd45a7cb457488bd50ee3
ToppCellsevere-Classical_Monocyte|severe / disease stage, cell group and cell class

CD44 LRP1 MPEG1 EVI2A LTA4H

5.32e-061975751263f141fd03a9294127ab5572893f7ae8b49230
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic-Neutrophil-Neu_c1-IL1B|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TRIM25 NFIL3 CD44 EVI2A PREX1

5.32e-061975753cd1c816bc7a57278b2ef615b69545356ab8f522
ToppCell10x3'2.3-week_14-16-Myeloid_neutrophil-granulo-neutrophil|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

CD44 MPEG1 EVI2A LTA4H IQGAP1

5.46e-061985759b29232c8b4dcbd81f450f47c3f79bf26c8fb583
ToppCellCOVID-19_Mild-Classical_Monocyte|COVID-19_Mild / Disease condition and Cell class

NFIL3 CD44 LRP1 MPEG1 EVI2A

5.46e-0619857530ada3de865b6fb2b14196a1cbfd4740c6a57ce3
ToppCellBronchial-10x5prime-Immune_Myeloid-Macrophage_alveolar-Macro_alv_MT|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SLC25A34 CD44 LRP1 MPEG1 LTA4H

5.59e-06199575a1ff1063741f6e5569feb44245785c9f472799b2
ToppCellCOVID-19_Severe-Classical_Monocyte|COVID-19_Severe / Disease condition and Cell class

CD44 LRP1 MPEG1 EVI2A LTA4H

5.59e-06199575ea1e2ccde3930fab6d04a9bf130837455c742474
ToppCellSepsis-Int-URO-Myeloid-CD14+_Monocyte|Int-URO / Disease, condition lineage and cell class

CD44 LRP1 MPEG1 LTA4H IQGAP1

5.73e-062005757471a202c36800f488a738c6803d9fb3fe167aad
ToppCellSepsis-Bac-SEP-Myeloid-CD14+_Monocyte|Bac-SEP / Disease, condition lineage and cell class

LRP1 MPEG1 EVI2A LTA4H IQGAP1

5.73e-062005751958c32c728a250e08c6313c40e3582dcff564c3
ToppCellSepsis-URO-Myeloid-CD14+_Monocyte|URO / Disease, condition lineage and cell class

CD44 LRP1 MPEG1 LTA4H IQGAP1

5.73e-06200575209976dbbfc1edbeb3ea128cd0453ec9572f54cb
ToppCellmLN-Macrophage-LYVE1_Macrophage|Macrophage / Region, Cell class and subclass

LRP1 ANKRD11 PKN2 XPO1 IQGAP1

5.73e-06200575e3c15e0e1c2602b0cc9ab8cc50c978d265350c94
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SAMD9L ANKRD11 PKN2 XPO1 UTRN

5.73e-0620057512f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellBronchial-NucSeq-Immune_Lymphocytic-T-T_CD4-CD4_naive/CM|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PIK3CD SERINC5 PREX1 FGD3 CASK

5.73e-06200575e0cec0a844b7c1f8edee4c005af27766754e470a
ToppCellmild-HLA-DR-_S100A+_Monocyte|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

NFIL3 LRP1 MPEG1 EVI2A LTA4H

5.73e-062005756dd89835a9f7bebb4849cff8eecb82caf6e1acbf
ToppCellBronchial-NucSeq-Immune_Lymphocytic-T-T_CD4-CD4|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SLC4A7 PIK3CD PREX1 KLRB1 FGD3

5.73e-062005758474e5d031d25bfb8461d39fa2053da01a6304fc
ToppCell10x5'v1-week_14-16-Myeloid_monocytic-monocyte-CD14_monocyte|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

CD44 LRP1 MPEG1 EVI2A LTA4H

5.73e-06200575f65837b51bce94c08125b1a2e1a696a15267f64b
ToppCellEnterocyte-C_02|Enterocyte / shred on cell type and cluster

CD44 ANKRD11 UTRN FREM1

2.79e-05136574daf11618c65e8fa2d77001b5c277d534cc012a4b
ToppCellfacs-Pancreas-Exocrine-3m-Hematologic-leukocyte|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIK3CD MPEG1 EVI2A PREX1

3.88e-05148574bbf4933582b50b3412c805de5ed137107c996236
ToppCellfacs-Pancreas-Exocrine-3m-Hematologic-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIK3CD MPEG1 EVI2A PREX1

3.88e-051485746543860e3207a7de92a35bb6004be51287582f7a
ToppCellfacs-Pancreas-Exocrine-3m-Hematologic|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIK3CD MPEG1 EVI2A PREX1

3.88e-0514857479e376503a3f9504a1ec5af4a60a09cc80e19059
ToppCellfacs-Heart-RV-18m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD44 MPEG1 EVI2A FGD3

4.41e-05153574af0ae08ff35f8210268457e5e15bcbe5d1f46d67
ToppCellfacs-Heart-RV-18m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD44 MPEG1 EVI2A FGD3

4.41e-05153574984a2d847f4376183fdbab7ebc77c1bf7d448f44
ToppCellfacs-Lung-nan-3m-Myeloid-Intermediate_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NFIL3 MPEG1 EVI2A PREX1

4.76e-051565743f0b9e35d4da85c90759b930052e5b9c3cde9b15
ToppCellfacs-Lung-nan-3m-Myeloid-intermediate_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NFIL3 MPEG1 EVI2A PREX1

4.76e-0515657469e6e8810d1738a66c9821910f41498931cf30cc
ToppCellfacs-Lung-EPCAM-3m-Myeloid-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIM25 LRP1 MPEG1 EVI2A

5.00e-05158574ef5feb48161c339c7b71c576bdda61479d29dfac
ToppCellPND28-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CD44 PERP LRP1 MPEG1

5.00e-051585746811dc4f101dfa9a9cc13d949760d43aa522bf3b
ToppCellfacs-Lung-EPCAM-3m-Myeloid-Classical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIM25 LRP1 MPEG1 EVI2A

5.00e-05158574c6e64b9b3342e37d54baadae8fb7dfb5d246e4cf
ToppCell3'-Airway_Nasal-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes-Classical_monocytes_L.1.2.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MPEG1 EVI2A LTA4H FGD3

5.38e-051615743a5f2877e3b29463a3a6da05009b0ab8747b4c47
ToppCell3'-GW_trimst-2-SmallIntestine-Hematopoietic-T_cells-ILCP|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CYP24A1 CD44 EVI2A KLRB1

5.38e-051615746d9907e2949a742c0933128fde57832a9ca5f77c
ToppCellPND28-Immune-Immune_Myeloid-Monocytic-Macrophage-AM|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CD44 PERP LRP1 MPEG1

5.51e-05162574d712bc31840ad1523e3dbf884acbb428a8995001
ToppCellfacs-MAT-Fat-3m-Myeloid-nan|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD44 MPEG1 EVI2A PREX1

5.78e-051645741250876abd7311f86730e5b9c03c3610cc2ff6d3
ToppCelldroplet-Lung-21m-Hematologic-myeloid-intermediate_monocyte|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NFIL3 LRP1 MPEG1 EVI2A

5.78e-05164574cd0794f84dfd346807e2d803723718b7f22e9232
ToppCelldroplet-Lung-21m-Hematologic-myeloid-intermediate_monocyte-intermediate_monocyte_l4|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NFIL3 LRP1 MPEG1 EVI2A

5.78e-0516457412251a49fd4af32d4edb58046245548c260cf04b
ToppCell3'_v3-Lung-Lymphocytic_B_plasma-Plasma_cells|Lung / Manually curated celltypes from each tissue

CBY3 EPHA6 PKHD1L1 PRAME

5.78e-051645743b6a32ba53d05f6818fe950ac426f489383b645a
ToppCellfacs-MAT-Fat-3m-Myeloid|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD44 MPEG1 EVI2A PREX1

5.78e-05164574fa0d77b648cde5e42b9394e877168c80de238bde
ToppCelldroplet-Kidney-nan-24m-Myeloid-CD45____macrophage|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCARB1 CD44 LRP1 MPEG1

5.78e-05164574d57faa4fce1f1e9a92aaf5cb920af99323252e4b
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Myeloid-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD44 MPEG1 EVI2A IQGAP1

5.78e-0516457445a6d809d92fd4eee906da3c812282bacffc9f2f
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD44 MPEG1 EVI2A IQGAP1

5.78e-05164574aa4358311fc767c292897e3328309d1bcda392d4
ToppCelldroplet-Kidney-nan-24m-Myeloid-macrophage|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCARB1 CD44 LRP1 MPEG1

5.78e-05164574d0b6c29e61d15f4dbe4c1f6e5ed3e10f41f820ab
ToppCelldroplet-Kidney-nan-24m-Myeloid|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCARB1 CD44 LRP1 MPEG1

5.78e-05164574718cc64b7ef7d03d095be4b2b54c449154da568c
ToppCellfacs-BAT-Fat-3m-Myeloid-myeloid_cell|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NFIL3 CD44 MPEG1 EVI2A

5.92e-05165574bfe330751d34813af7540765b490406078c40da7
ToppCellfacs-Lung-nan-3m-Myeloid|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIM25 NFIL3 CD44 MPEG1

5.92e-05165574720649f330382ea2a68c64a5344160a048afb8f1
ToppCellfacs-BAT-Fat-3m-Myeloid|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NFIL3 CD44 MPEG1 EVI2A

5.92e-051655748bdeacbb47948fabae2575689f811a9fad47f779
ToppCelldroplet-Spleen-nan-18m-Hematologic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NFIL3 SCARB1 LRP1 MPEG1

6.06e-05166574e841e62cb20235d6233f78f4155fb8c0ffb1ef1b
ToppCellfacs-Lung-EPCAM-18m-Myeloid-Classical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIK3CD NFIL3 MPEG1 EVI2A

6.06e-05166574bf6c35c3e67ef4ca98a38926c6f7923ecca0508a
ToppCelldroplet-Spleen-nan-18m-Hematologic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NFIL3 SCARB1 LRP1 MPEG1

6.06e-051665743ca3ddb663644f0e7f70f9b75833bb54cd9191d3
ToppCellfacs-Lung-EPCAM-18m-Myeloid-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIK3CD NFIL3 MPEG1 EVI2A

6.06e-05166574433128b7d964b32faa0bf437a02facc819ab1405
ToppCelldroplet-Spleen-nan-18m-Hematologic-proerythroblast|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NFIL3 SCARB1 LRP1 MPEG1

6.06e-05166574f751cbd01d4978ded7755874ab60504f6291afd7
ToppCell(0)_Myeloid-(00)_Monocyte-(000)_CD14+_Monocyte|(00)_Monocyte / immune cells in Peripheral Blood (logTPM normalization)

NFIL3 LRP1 EVI2A XPO1

6.20e-051675747d9fd6a7a45c2aa0d5f2e3960ca4c97ee8836ba5
ToppCelldroplet-Lung-nan-18m-Myeloid|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NFIL3 CD44 MPEG1 EVI2A

6.35e-05168574da1eee804456d910c17f145a5ce79c74a808a2c2
ToppCelldroplet-Spleen-SPLEEN-1m-Hematologic-proerythroblast|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCARB1 LRP1 MPEG1 CASK

6.35e-05168574f3b7a7df54988de77dcc7066e2fc1feb9c280b13
ToppCellfacs-Lung-18m-Hematologic-myeloid-classical_monocyte|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PIK3CD NFIL3 MPEG1 EVI2A

6.35e-051685740ffad93ba2fb5d4cfda2c13011059555475dcfc8
ToppCellfacs-Lung-18m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PIK3CD NFIL3 MPEG1 EVI2A

6.35e-05168574ab1fb9b2cc7c5853b7fbd373e1784a9a31f96d38
ToppCellfacs-Lung-EPCAM-24m-Myeloid-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NFIL3 LRP1 MPEG1 EVI2A

6.50e-05169574c934cf5b6decf6eee78243ee15c2a2c71e14cf71
ToppCellfacs-Liver-Non-hepatocytes-24m-Myeloid-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD44 MPEG1 EVI2A IQGAP1

6.50e-051695742d3618f78484bd3508b7bdae3a0d0183cdae5057
ToppCellfacs-GAT-Fat-18m-Myeloid-nan|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD44 MPEG1 EVI2A PREX1

6.50e-051695747a7416fcbffcf57d19b477d9da091e04e3499524
ToppCellfacs-Lung-EPCAM-24m-Myeloid-Classical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NFIL3 LRP1 MPEG1 EVI2A

6.50e-051695747503373fd9020c923e7eb96c7695f34054438e9e
ToppCellfacs-GAT-Fat-18m-Myeloid|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD44 MPEG1 EVI2A PREX1

6.50e-051695740e1a99cd77edcf32bcb513abd247b2b27409ac63
ToppCellfacs-GAT-Fat-18m-Myeloid-myeloid_cell|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD44 MPEG1 EVI2A PREX1

6.50e-051695749bbad31ef03078f5aa456f2e1b17b49c91545ff0
ToppCellfacs-Liver-Non-hepatocytes-24m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD44 MPEG1 EVI2A IQGAP1

6.65e-05170574f08aa6168ff0c20b2083dbf588dd3294e3d9580e
ToppCelldroplet-Thymus-nan-21m-Myeloid-professional_antigen_presenting_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LIFR CD44 MPEG1 EVI2A

6.65e-0517057429deb285d5a82c0abcc108012ca42f4b4b4d9e19
ToppCelldroplet-Thymus-nan-21m-Myeloid|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LIFR CD44 MPEG1 EVI2A

6.65e-05170574dc35d66a9a9fe6cdd7f4ec0fe7efa49d02f2b5b2
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NPFFR2 LRP1 NFASC LRP1B

6.65e-051705745570c0e825bca77613bf0ebde620cf744fa1cb84
Drugmangrove

ABCA1 FADS3 PIK3CD CD44 LRP1 ANKRD11 LTA4H PKN2 LRP1B

2.28e-06468579CID000000965
Diseaseovary adenocarcinoma (is_marker_for)

CYP24A1 PRAME

9.85e-063542DOID:3713 (is_marker_for)
Diseaselung adenocarcinoma (is_marker_for)

CYP24A1 CD44 XPO1 PRAME

1.82e-0585544DOID:3910 (is_marker_for)
Diseasecolorectal cancer (is_implicated_in)

PIK3CD CYP24A1 XPO1 LRP1B

7.26e-05121544DOID:9256 (is_implicated_in)
Diseasesphingomyelin measurement

ABCA1 FADS3 NFIL3 SCARB1 ANKRD11

1.55e-04278545EFO_0010118
Diseasegastric adenocarcinoma (is_implicated_in)

CD44 XPO1

1.79e-0411542DOID:3717 (is_implicated_in)
Diseasecongenital diaphragmatic hernia (implicated_via_orthology)

LRP1 FREM1

2.14e-0412542DOID:3827 (implicated_via_orthology)
Diseaselevel of Phosphatidylcholine (O-18:1_20:4) in blood serum

FADS3 SCARB1

3.40e-0415542OBA_2045131
Diseaselevel of Phosphatidylcholine (18:1_20:4) in blood serum

ABCA1 FADS3

6.75e-0421542OBA_2045104
Diseasesystemising measurement

PIK3CD ERLEC1

6.75e-0421542EFO_0010221
DiseaseAttention Deficit Disorder

STS GRM5

7.42e-0422542C0041671
DiseaseMinimal Brain Dysfunction

STS GRM5

7.42e-0422542C1321905
Diseaseapolipoprotein A 1 measurement

ABCA1 FADS3 SCARB1 YLPM1 LRP1 GRM5 FARP2

8.64e-04848547EFO_0004614
Diseasehair colour measurement

SCARB1 CD44 LRP1 ANKRD11 SERINC5 GRM5

8.84e-04615546EFO_0007822
DiseaseAttention deficit hyperactivity disorder

STS GRM5

8.84e-0424542C1263846
DiseaseAlzheimer disease, high density lipoprotein cholesterol measurement

ABCA1 SCARB1

1.04e-0326542EFO_0004612, MONDO_0004975
Diseaseantihyperlipidemic drug use measurement

NPFFR2 ABCA1 SCARB1

1.24e-03115543EFO_0803367
Diseasecoffee consumption

LAMB4 YLPM1

1.57e-0332542EFO_0004330
Diseasemelanoma

ANKRD11 GRM5 FARP2

1.61e-03126543EFO_0000756
DiseasePapillary Renal Cell Carcinoma

SCARB1 LRP1B PRAME

1.68e-03128543C1306837
DiseaseRenal Cell Carcinoma

SCARB1 LRP1B PRAME

1.68e-03128543C0007134
DiseaseSarcomatoid Renal Cell Carcinoma

SCARB1 LRP1B PRAME

1.68e-03128543C1266043
DiseaseChromophobe Renal Cell Carcinoma

SCARB1 LRP1B PRAME

1.68e-03128543C1266042
DiseaseCollecting Duct Carcinoma of the Kidney

SCARB1 LRP1B PRAME

1.68e-03128543C1266044
Diseasephosphatidylcholine measurement

ABCA1 MALRD1 FADS3 SCARB1

1.82e-03284544EFO_0010226

Protein segments in the cluster

PeptideGeneStartEntry
WNQEEHIEWAKKNTA

ERLEC1

381

Q96DZ1
QHTKHWRTDNWKTIS

ANKRD11

541

Q6UB99
TEDNIKVWFNNKGWH

ABCA4

1611

P78363
TKNNVKVWFNNKGWH

ABCA1

1586

O95477
SQQLPHCSQSWAQWK

CDRT15P3

106

P0DPF6
TAWGWKAQVQRSKSQ

CBY3

156

A6NI87
LAVGDNNSKWVKHWV

IQGAP1

676

P46940
FQVAKKEGSWWHCNS

RANBP2

1346

P49792
SSENWHPIWNVNDTK

NPFFR2

111

Q9Y5X5
NGAFINWKEAKLTWS

RFT1

231

Q96AA3
ENARSWIKDSQTHQW

MPEG1

616

Q2M385
SWTGNLVTNKTWDHF

LTA4H

301

P09960
IQIISKDDHNWWQGK

CASK

646

O14936
KDDHNWWQGKLENSK

CASK

651

O14936
TWAQNEKSSRGQHLW

GRM5

916

P41594
DWRTNTLSKANKWTG

LRP1B

1486

Q9NZR2
WRTNTLAKANKWTGH

LRP1

1496

Q07954
LQSSDHGQTSSLWWK

PERP

36

Q96FX8
WGDSSWNKTQAKQVS

PGLYRP4

16

Q96LB8
TNIQDWSLKSEHWHQ

NFIL3

386

Q16649
WANSTSSWDSVIQNK

EVI2A

36

P22794
SNQSKHSTWEKGIWH

FREM1

1861

Q5H8C1
LDSGHVWKLQWAKQS

FGD3

666

Q5JSP0
SKVWQESKQNPGNHW

MALRD1

1621

Q5VYJ5
LPNSKWANITWKHNF

NFASC

1126

O94856
WSAKTLHTWQKCSNR

FZD4

496

Q9ULV1
TATQKEQWFGNRWHE

CD44

396

P16070
KSLNTKVWQDHTLAW

CYP24A1

261

Q07973
KDQNKNSFVGWSTDW

ACE2

596

Q9BYF1
EAEQTKNSGTEHWWK

IPO9

431

Q96P70
EKKWWQSENGLDHVS

LAMB4

101

A4D0S4
KNSHGWQKLWVVFTN

FARP2

941

O94887
HASIFKKSWWNHVAQ

FADS3

186

Q9Y5Q0
NTTLNGKDTLHHWSW

LIFR

191

P42702
KDWASQNSIALSWQA

EPHA6

451

Q9UF33
WKNNGNVNSSWKSEP

RUSC1

256

Q9BVN2
KWESLNAVTSNWQKQ

UTRN

2671

P46939
QWKKDNITAHNISWR

SLC4A7

781

Q9Y6M7
KNSHQDFWTVWSGNR

PRAME

126

P78395
ATFASAKAWVQKQQW

SLC25A34

186

Q6PIV7
QNTNSLWHSGDVWKK

SAMD9L

1501

Q8IVG5
DQLWKLMNSGTSHDW

TAF2

951

Q6P1X5
TNGWKIHNTAKNKWF

PREX1

356

Q8TCU6
NAVRWHPQNSTSIWK

STS

451

P08842
KWNGLSKVDFWHSDQ

SCARB1

236

Q8WTV0
QTSWKPISNQSWDQK

PKN2

406

Q16513
HNQVNGTEWSWKNLN

XPO1

481

O14980
VFNWWSQLTNHKKIH

ZNF678

161

Q5SXM1
CDKVFNWWSQLTSHK

ZNF678

186

Q5SXM1
NWWSQLTSHKKIHSG

ZNF678

191

Q5SXM1
SSWDKNLKIWNVHTG

WDR88

291

Q6ZMY6
WASKGKLEWQHIHQQ

SPATA31D1

471

Q6ZQQ2
VEWFNTKISAWHNNV

TRIM25

551

Q14258
FAHKWNKNWTAGTAS

SERINC5

176

Q86VE9
NKNWTAGTASNKLWY

SERINC5

181

Q86VE9
TAFAHSWNKNWQTGA

SERINC4

201

A6NH21
SWKTKVNWLAHNVSK

PIK3CD

1026

O00329
NWNTSKNGDWHLEAN

PKHD1L1

2951

Q86WI1
QWKTWQGHMKATQSY

YLPM1

481

P49750
WQSWQEKHPGQALSS

TGS1

211

Q96RS0
SEKNWKWINGSFLNS

KLRB1

161

Q12918