Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	protein-lysine 6-oxidase activity	LOXL1 LOXL2 LOXL4 LOXL3	1.47e-10	5	48	4	GO:0004720
GeneOntologyMolecularFunction	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	LOXL1 LOXL2 LOXL4 LOXL3	5.24e-08	16	48	4	GO:0016641
GeneOntologyMolecularFunction	oxidoreductase activity, acting on the CH-NH2 group of donors	LOXL1 LOXL2 LOXL4 LOXL3	1.38e-07	20	48	4	GO:0016638
GeneOntologyMolecularFunction	metallocarboxypeptidase activity	CPA6 CPO CPA3 CPB1	8.82e-07	31	48	4	GO:0004181
GeneOntologyMolecularFunction	carboxypeptidase activity	CPA6 CPO CPA3 CPB1	5.75e-06	49	48	4	GO:0004180
GeneOntologyMolecularFunction	transition metal ion binding	CPA6 RTL3 P3H3 LOXL1 LOXL2 CPO LOXL4 CPA3 CPB1 LOXL3 ZSWIM6 RABGGTA	1.77e-05	1189	48	12	GO:0046914
GeneOntologyMolecularFunction	metalloexopeptidase activity	CPA6 CPO CPA3 CPB1	2.40e-05	70	48	4	GO:0008235
GeneOntologyMolecularFunction	copper ion binding	LOXL1 LOXL2 LOXL4 LOXL3	3.68e-05	78	48	4	GO:0005507
GeneOntologyMolecularFunction	amino acid:proton symporter activity	SLC36A1 SLC36A3	8.44e-05	6	48	2	GO:0005280
GeneOntologyMolecularFunction	metallopeptidase activity	CPA6 CPO CPA3 CPB1 SPRTN	1.16e-04	200	48	5	GO:0008237
GeneOntologyMolecularFunction	L-proline transmembrane transporter activity	SLC36A1 SLC36A3	1.18e-04	7	48	2	GO:0015193
GeneOntologyMolecularFunction	exopeptidase activity	CPA6 CPO CPA3 CPB1	1.41e-04	110	48	4	GO:0008238
GeneOntologyMolecularFunction	L-alanine transmembrane transporter activity	SLC36A1 SLC36A3	2.02e-04	9	48	2	GO:0015180
GeneOntologyMolecularFunction	glycine transmembrane transporter activity	SLC36A1 SLC36A3	2.52e-04	10	48	2	GO:0015187
GeneOntologyMolecularFunction	alanine transmembrane transporter activity	SLC36A1 SLC36A3	6.65e-04	16	48	2	GO:0022858
GeneOntologyMolecularFunction	prenyltransferase activity	FDPS RABGGTA	8.45e-04	18	48	2	GO:0004659
GeneOntologyMolecularFunction	solute:proton symporter activity	SLC36A1 SLC36A3	1.64e-03	25	48	2	GO:0015295
GeneOntologyMolecularFunction	amino acid:monoatomic cation symporter activity	SLC36A1 SLC36A3	2.20e-03	29	48	2	GO:0005416
GeneOntologyMolecularFunction	neutral L-amino acid transmembrane transporter activity	SLC36A1 SLC36A3	4.37e-03	41	48	2	GO:0015175
GeneOntologyMolecularFunction	zinc ion binding	CPA6 RTL3 CPO CPA3 CPB1 ZSWIM6 RABGGTA	5.13e-03	891	48	7	GO:0008270
GeneOntologyBiologicalProcess	peptidyl-lysine oxidation	LOXL1 LOXL2 LOXL4 LOXL3	1.18e-10	5	47	4	GO:0018057
GeneOntologyBiologicalProcess	protein oxidation	LOXL1 LOXL2 LOXL4 LOXL3	2.33e-08	14	47	4	GO:0018158
GeneOntologyBiologicalProcess	collagen fibril organization	COL12A1 LOXL1 LOXL2 LOXL4 LOXL3	8.08e-07	76	47	5	GO:0030199
GeneOntologyBiologicalProcess	peptidyl-lysine modification	P3H3 LOXL1 LOXL2 LOXL4 LOXL3	3.30e-05	162	47	5	GO:0018205
GeneOntologyBiologicalProcess	extracellular matrix organization	COL12A1 LOXL1 LOXL2 LAMA2 LOXL4 LOXL3	2.04e-04	377	47	6	GO:0030198
GeneOntologyBiologicalProcess	extracellular structure organization	COL12A1 LOXL1 LOXL2 LAMA2 LOXL4 LOXL3	2.07e-04	378	47	6	GO:0043062
GeneOntologyBiologicalProcess	external encapsulating structure organization	COL12A1 LOXL1 LOXL2 LAMA2 LOXL4 LOXL3	2.10e-04	379	47	6	GO:0045229
GeneOntologyBiologicalProcess	embryonic process involved in female pregnancy	SP1 SP3	2.26e-04	10	47	2	GO:0060136
GeneOntologyBiologicalProcess	proline transmembrane transport	SLC36A1 SLC36A3	2.76e-04	11	47	2	GO:0035524
GeneOntologyBiologicalProcess	L-alanine transport	SLC36A1 SLC36A3	2.76e-04	11	47	2	GO:0015808
GeneOntologyBiologicalProcess	positive regulation of integrin-mediated signaling pathway	LAMA2 LOXL3	4.54e-04	14	47	2	GO:2001046
GeneOntologyBiologicalProcess	myeloid progenitor cell differentiation	SP1 SP3	4.54e-04	14	47	2	GO:0002318
GeneOntologyBiologicalProcess	glycine transport	SLC36A1 SLC36A3	5.24e-04	15	47	2	GO:0015816
GeneOntologyBiologicalProcess	enucleate erythrocyte differentiation	SP1 SP3	5.98e-04	16	47	2	GO:0043353
GeneOntologyBiologicalProcess	alanine transport	SLC36A1 SLC36A3	7.60e-04	18	47	2	GO:0032328
GeneOntologyCellularComponent	collagen-containing extracellular matrix	COL12A1 LOXL1 LOXL2 LAMA2 LOXL4 CPA3 LOXL3	2.21e-04	530	49	7	GO:0062023
GeneOntologyCellularComponent	extracellular matrix	COL12A1 LOXL1 LOXL2 LAMA2 LOXL4 CPA3 LOXL3	7.93e-04	656	49	7	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	COL12A1 LOXL1 LOXL2 LAMA2 LOXL4 CPA3 LOXL3	8.07e-04	658	49	7	GO:0030312
Domain	Lysyl_oxidase	LOXL1 LOXL2 LOXL4 LOXL3	2.27e-10	5	50	4	IPR001695
Domain	Lysyl_oxidase_CS	LOXL1 LOXL2 LOXL4 LOXL3	2.27e-10	5	50	4	IPR019828
Domain	LYSYL_OXIDASE	LOXL1 LOXL2 LOXL4 LOXL3	2.27e-10	5	50	4	PS00926
Domain	Lysyl_oxidase	LOXL1 LOXL2 LOXL4 LOXL3	2.27e-10	5	50	4	PF01186
Domain	Sp1_fam	SP8 SP1 SP3 SP5	9.43e-09	10	50	4	IPR030450
Domain	Zn_pept	CPA6 CPO CPA3 CPB1	1.35e-07	18	50	4	SM00631
Domain	CARBOXYPEPT_ZN_2	CPA6 CPO CPA3 CPB1	1.71e-07	19	50	4	PS00133
Domain	CARBOXYPEPT_ZN_1	CPA6 CPO CPA3 CPB1	2.13e-07	20	50	4	PS00132
Domain	SRCR	LOXL2 LOXL4 LOXL3 CD163	2.63e-07	21	50	4	PF00530
Domain	Peptidase_M14	CPA6 CPO CPA3 CPB1	3.88e-07	23	50	4	PF00246
Domain	Peptidase_M14	CPA6 CPO CPA3 CPB1	3.88e-07	23	50	4	IPR000834
Domain	SR	LOXL2 LOXL4 LOXL3 CD163	5.51e-07	25	50	4	SM00202
Domain	-	LOXL2 LOXL4 LOXL3 CD163	5.51e-07	25	50	4	3.10.250.10
Domain	SRCR_1	LOXL2 LOXL4 LOXL3 CD163	6.50e-07	26	50	4	PS00420
Domain	SRCR-like_dom	LOXL2 LOXL4 LOXL3 CD163	6.50e-07	26	50	4	IPR017448
Domain	SRCR_2	LOXL2 LOXL4 LOXL3 CD163	6.50e-07	26	50	4	PS50287
Domain	SRCR	LOXL2 LOXL4 LOXL3 CD163	7.62e-07	27	50	4	IPR001190
Domain	-	CPA6 CPA3 CPB1	1.00e-06	8	50	3	3.30.70.340
Domain	Propep_M14	CPA6 CPA3 CPB1	1.00e-06	8	50	3	PF02244
Domain	M14A_act_pep	CPA6 CPA3 CPB1	1.00e-06	8	50	3	IPR003146
Domain	Propept_inh	CPA6 CPA3 CPB1	1.20e-05	17	50	3	IPR009020
Domain	SEA	MUC3B MUC3A	6.26e-04	14	50	2	SM00200
Domain	Aa_trans	SLC36A1 SLC36A3	9.31e-04	17	50	2	PF01490
Domain	AA_transpt_TM	SLC36A1 SLC36A3	9.31e-04	17	50	2	IPR013057
Domain	SEA	MUC3B MUC3A	1.71e-03	23	50	2	PS50024
Domain	SEA_dom	MUC3B MUC3A	1.71e-03	23	50	2	IPR000082
Domain	G_PROTEIN_RECEP_F2_1	GIPR ADGRD2	5.13e-03	40	50	2	PS00649
Domain	G_PROTEIN_RECEP_F2_3	GIPR ADGRD2	5.13e-03	40	50	2	PS50227
Domain	GPCR_2_extracellular_dom	GIPR ADGRD2	5.13e-03	40	50	2	IPR001879
Domain	G_PROTEIN_RECEP_F2_2	GIPR ADGRD2	7.93e-03	50	50	2	PS00650
Domain	7tm_2	GIPR ADGRD2	7.93e-03	50	50	2	PF00002
Domain	zf-C2H2	SP8 SP1 SP3 FBXO41 SP5 REPIN1	1.01e-02	693	50	6	PF00096
Domain	Laminin_G	COL12A1 LAMA2	1.06e-02	58	50	2	IPR001791
Domain	GPCR_2-like	GIPR ADGRD2	1.13e-02	60	50	2	IPR017981
Domain	GPCR_2_secretin-like	GIPR ADGRD2	1.13e-02	60	50	2	IPR000832
Domain	G_PROTEIN_RECEP_F2_4	GIPR ADGRD2	1.16e-02	61	50	2	PS50261
Pathway	REACTOME_COLLAGEN_FORMATION	COL12A1 P3H3 LOXL1 LOXL2 LOXL4 LOXL3	1.08e-08	76	30	6	MM14573
Pathway	REACTOME_COLLAGEN_FORMATION	COL12A1 P3H3 LOXL1 LOXL2 LOXL4 LOXL3	3.00e-08	90	30	6	M631
Pathway	REACTOME_CROSSLINKING_OF_COLLAGEN_FIBRILS	LOXL1 LOXL2 LOXL4 LOXL3	4.99e-08	18	30	4	M27164
Pathway	REACTOME_CROSSLINKING_OF_COLLAGEN_FIBRILS	LOXL1 LOXL2 LOXL4 LOXL3	4.99e-08	18	30	4	MM14882
Pathway	REACTOME_ASSEMBLY_OF_COLLAGEN_FIBRILS_AND_OTHER_MULTIMERIC_STRUCTURES	COL12A1 LOXL1 LOXL2 LOXL4 LOXL3	6.09e-08	50	30	5	MM14796
Pathway	REACTOME_ASSEMBLY_OF_COLLAGEN_FIBRILS_AND_OTHER_MULTIMERIC_STRUCTURES	COL12A1 LOXL1 LOXL2 LOXL4 LOXL3	1.68e-07	61	30	5	M27103
Pathway	REACTOME_ELASTIC_FIBRE_FORMATION	LOXL1 LOXL2 LOXL4 LOXL3	1.30e-06	39	30	4	MM14601
Pathway	REACTOME_ELASTIC_FIBRE_FORMATION	LOXL1 LOXL2 LOXL4 LOXL3	2.13e-06	44	30	4	M26969
Pathway	REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION	COL12A1 P3H3 LOXL1 LOXL2 LAMA2 LOXL4 LOXL3	2.46e-06	300	30	7	M610
Pathway	WP_CANONICAL_AND_NONCANONICAL_TGFB_SIGNALING	LOXL1 LOXL2 LOXL4	5.80e-06	17	30	3	M39686
Pathway	REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION	COL12A1 P3H3 LOXL1 LOXL2 LOXL4 LOXL3	1.46e-05	258	30	6	MM14572
Pathway	WP_ESTRADIOL_REGULATION_IN_PORTOSINUSOIDAL_VASCULAR_DISEASE	SP1 SP3	4.36e-05	5	30	2	M45554
Pathway	BIOCARTA_TERC_PATHWAY	SP1 SP3	6.53e-05	6	30	2	MM1564
Pathway	BIOCARTA_TERC_PATHWAY	SP1 SP3	6.53e-05	6	30	2	M22047
Pathway	BIOCARTA_TERT_PATHWAY	SP1 SP3	9.13e-05	7	30	2	MM1541
Pathway	BIOCARTA_TERT_PATHWAY	SP1 SP3	1.22e-04	8	30	2	M22015
Pathway	REACTOME_METABOLISM_OF_ANGIOTENSINOGEN_TO_ANGIOTENSINS	CPA3 CPB1	4.52e-04	15	30	2	MM14797
Pathway	REACTOME_METABOLISM_OF_ANGIOTENSINOGEN_TO_ANGIOTENSINS	CPA3 CPB1	5.84e-04	17	30	2	M27104
Pathway	BIOCARTA_CALCINEURIN_PATHWAY	SP1 SP3	6.56e-04	18	30	2	M3430
Pathway	BIOCARTA_CALCINEURIN_PATHWAY	SP1 SP3	6.56e-04	18	30	2	MM1385
Pathway	WP_FATTY_ACIDS_AND_LIPOPROTEINS_TRANSPORT_IN_HEPATOCYTES	FDPS LOXL2 LOXL4 LOXL3 CD163	1.15e-03	381	30	5	M48063
Pathway	BIOCARTA_AGR_PATHWAY	SP1 LAMA2	1.96e-03	31	30	2	MM1343
Pathway	WP_METABOLIC_PATHWAYS_OF_FIBROBLASTS	P3H3 LOXL2	2.09e-03	32	30	2	M48055
Pathway	BIOCARTA_AGR_PATHWAY	SP1 LAMA2	2.22e-03	33	30	2	M6220
Pubmed	Structural and functional diversity of lysyl oxidase and the LOX-like proteins.	LOXL1 LOXL2 LOXL4 LOXL3	4.10e-12	4	51	4	12686136
Pubmed	Common polymorphisms in human lysyl oxidase genes are not associated with the adolescent idiopathic scoliosis phenotype.	LOXL1 LOXL2 LOXL4 LOXL3	2.05e-11	5	51	4	21740577
Pubmed	Systematic screening of lysyl oxidase-like (LOXL) family genes demonstrates that LOXL2 is a susceptibility gene to intracranial aneurysms.	LOXL1 LOXL2 LOXL4 LOXL3	6.14e-11	6	51	4	17287949
Pubmed	Lysyl oxidase (lox) gene deficiency affects osteoblastic phenotype.	LOXL1 LOXL2 LOXL4 LOXL3	2.86e-10	8	51	4	19458888
Pubmed	TGF-beta1 induces the different expressions of lysyl oxidases and matrix metalloproteinases in anterior cruciate ligament and medial collateral ligament fibroblasts after mechanical injury.	LOXL1 LOXL2 LOXL4 LOXL3	8.55e-10	10	51	4	23357697
Pubmed	Lysyl oxidase-like 4 is alternatively spliced in an anatomic site-specific manner in tumors involving the serosal cavities.	LOXL2 LOXL4 LOXL3	2.97e-09	3	51	3	19015874
Pubmed	The Sp transcription factor family is involved in the cellular expression of the human GIP-R gene promoter.	GIPR SP1 SP3	2.97e-09	3	51	3	15666829
Pubmed	Significance of the Lysyl Oxidase Members Lysyl Oxidase Like 1, 3, and 4 in Gastric Cancer.	LOXL1 LOXL4 LOXL3	2.97e-09	3	51	3	30045039
Pubmed	Loss of Lysyl Oxidase-like 3 Attenuates Embryonic Lung Development in Mice.	LOXL1 LOXL2 LOXL4 LOXL3	5.53e-09	15	51	4	27645581
Pubmed	Differential expression of the LOX family genes in human colorectal adenocarcinomas.	LOXL1 LOXL2 LOXL3	1.19e-08	4	51	3	19724858
Pubmed	Lysyl oxidases: a novel multifunctional amine oxidase family.	LOXL1 LOXL2 LOXL3	1.19e-08	4	51	3	11642359
Pubmed	Mammalian SP/KLF transcription factors: bring in the family.	SP8 SP1 SP3 SP5	5.07e-08	25	51	4	15820306
Pubmed	Nkx3.1 binds and negatively regulates the transcriptional activity of Sp-family members in prostate-derived cells.	SP1 SP3 SP5	5.92e-08	6	51	3	16201967
Pubmed	Localized LoxL3-Dependent Fibronectin Oxidation Regulates Myofiber Stretch and Integrin-Mediated Adhesion.	LOXL1 LOXL2 LOXL3	2.48e-07	9	51	3	26954549
Pubmed	Sp1 increases expression of cyclooxygenase-2 in hypoxic vascular endothelium. Implications for the mechanisms of aortic aneurysm and heart failure.	SP1 SP3	2.11e-06	2	51	2	10825178
Pubmed	HPV8 activates cellular gene expression mainly through Sp1/3 binding sites.	SP1 SP3	2.11e-06	2	51	2	31299490
Pubmed	MUC3 human intestinal mucin. Analysis of gene structure, the carboxyl terminus, and a novel upstream repetitive region.	MUC3B MUC3A	2.11e-06	2	51	2	9334251
Pubmed	Sp1 and Sp3 regulate transcription of the cyclin-dependent kinase 5 regulatory subunit 2 (p39) promoter in neuronal cells.	SP1 SP3	2.11e-06	2	51	2	19437621
Pubmed	LAMA2 and LOXL4 are candidate FSGS genes.	LAMA2 LOXL4	2.11e-06	2	51	2	34565340
Pubmed	Sp1 trans-activation of cell cycle regulated promoters is selectively repressed by Sp3.	SP1 SP3	2.11e-06	2	51	2	8845379
Pubmed	Initiation of transcription of the MUC3A human intestinal mucin from a TATA-less promoter and comparison with the MUC3B amino terminus.	MUC3B MUC3A	2.11e-06	2	51	2	12958310
Pubmed	Molecular cloning of cDNAs derived from a novel human intestinal mucin gene.	MUC3B MUC3A	2.11e-06	2	51	2	2393399
Pubmed	Concentration-dependent effects of endogenous S-nitrosoglutathione on gene regulation by specificity proteins Sp3 and Sp1.	SP1 SP3	2.11e-06	2	51	2	14766015
Pubmed	Associations of distinct variants of the intestinal mucin gene MUC3A with ulcerative colitis and Crohn's disease.	MUC3B MUC3A	2.11e-06	2	51	2	11289722
Pubmed	Sp1/Sp3 transcription factors regulate hallmarks of megakaryocyte maturation and platelet formation and function.	SP1 SP3	2.11e-06	2	51	2	25538045
Pubmed	Transcriptional control of human CD2AP expression: the role of Sp1 and Sp3.	SP1 SP3	2.11e-06	2	51	2	21604172
Pubmed	SP1 is a transcriptional regulator of URG-4/URGCP gene in hepatocytes.	SP1 URGCP	2.11e-06	2	51	2	27766531
Pubmed	Expression of the human endogenous retrovirus (HERV) group HML-2/HERV-K does not depend on canonical promoter elements but is regulated by transcription factors Sp1 and Sp3.	SP1 SP3	2.11e-06	2	51	2	21248046
Pubmed	Robust hematopoietic specification requires the ubiquitous Sp1 and Sp3 transcription factors.	SP1 SP3	2.11e-06	2	51	2	31164147
Pubmed	Specific protein 1(SP1) regulates the epithelial-mesenchymal transition via lysyl oxidase-like 2(LOXL2) in pancreatic ductal adenocarcinoma.	SP1 LOXL2	2.11e-06	2	51	2	30976063
Pubmed	Sp1 and Sp3 activate transcription of the human dopamine transporter gene.	SP1 SP3	2.11e-06	2	51	2	15816870
Pubmed	Sp family transcription factors regulate expression of rat D2 dopamine receptor gene.	SP1 SP3	2.11e-06	2	51	2	9628590
Pubmed	Transcriptional activity and Sp 1/3 transcription factor binding to the P1 promoter sequences of the human AbetaH-J-J locus.	SP1 SP3	2.11e-06	2	51	2	17681019
Pubmed	Endothelial Sp1/Sp3 are essential to the effect of captopril on blood pressure in male mice.	SP1 SP3	2.11e-06	2	51	2	37735515
Pubmed	The nuclear abundance of transcription factors Sp1 and Sp3 depends on biotin in Jurkat cells.	SP1 SP3	2.11e-06	2	51	2	14608051
Pubmed	Sp1 and Sp3 Are the Transcription Activators of Human ek1 Promoter in TSA-Treated Human Colon Carcinoma Cells.	SP1 SP3	2.11e-06	2	51	2	26807725
Pubmed	An Sp1/Sp3 binding polymorphism confers methylation protection.	SP1 SP3	2.11e-06	2	51	2	18725933
Pubmed	Lysyl oxidases regulate fibrillar collagen remodelling in idiopathic pulmonary fibrosis.	LOXL1 LOXL2	2.11e-06	2	51	2	29125826
Pubmed	Sp1/Sp3-dependent regulation of human telomerase reverse transcriptase promoter activity by the bioactive sphingolipid ceramide.	SP1 SP3	2.11e-06	2	51	2	15951564
Pubmed	Multiple transcripts of MUC3: evidence for two genes, MUC3A and MUC3B.	MUC3B MUC3A	2.11e-06	2	51	2	10973822
Pubmed	Differentiation-dependent and cell-specific regulation of the hIGFBP-1 gene in human endometrium.	SP1 SP3	2.11e-06	2	51	2	9329821
Pubmed	The MUC3 gene encodes a transmembrane mucin and is alternatively spliced.	MUC3B MUC3A	2.11e-06	2	51	2	10405327
Pubmed	Transcription factors Sp1 and Sp3 regulate basal transcription of the human IRF-3 gene.	SP1 SP3	2.11e-06	2	51	2	22464952
Pubmed	Sp1 and Sp3 Are important regulators of AP-2gamma gene transcription.	SP1 SP3	6.32e-06	3	51	2	12801994
Pubmed	Expression of the human melanocortin-4 receptor gene is controlled by several members of the Sp transcription factor family.	SP1 SP3	6.32e-06	3	51	2	15821099
Pubmed	Laminin reduces expression of the human alpha6 integrin subunit gene by altering the level of the transcription factors Sp1 and Sp3.	SP1 SP3	6.32e-06	3	51	2	17652716
Pubmed	Regulation of human CETP gene expression: role of SP1 and SP3 transcription factors at promoter sites -690, -629, and -37.	SP1 SP3	6.32e-06	3	51	2	12730302
Pubmed	Expression patterns of SP1 and SP3 during mouse spermatogenesis: SP1 down-regulation correlates with two successive promoter changes and translationally compromised transcripts.	SP1 SP3	6.32e-06	3	51	2	18417714
Pubmed	Activation of the RNA-dependent protein kinase PKR promoter in the absence of interferon is dependent upon Sp proteins.	SP1 SP3	6.32e-06	3	51	2	16339759
Pubmed	Sp1 and Sp3 are involved in up-regulation of human deoxyribonuclease II transcription during differentiation of HL-60 cells.	SP1 SP3	6.32e-06	3	51	2	12694199
Pubmed	Functional interplay of SP family members and nuclear factor Y is essential for transcriptional activation of the human Calreticulin gene.	SP1 SP3	6.32e-06	3	51	2	26162987
Pubmed	The copper dependent-lysyl oxidases contribute to the pathogenesis of pulmonary emphysema in chronic obstructive pulmonary disease patients.	LOXL1 LOXL2	6.32e-06	3	51	2	28965583
Pubmed	Transcriptional regulation of BACE1, the beta-amyloid precursor protein beta-secretase, by Sp1.	SP1 SP3	6.32e-06	3	51	2	14701757
Pubmed	Regulation of the human secretin gene is controlled by the combined effects of CpG methylation, Sp1/Sp3 ratio, and the E-box element.	SP1 SP3	6.32e-06	3	51	2	15118068
Pubmed	Involvement of the GC-rich sequence and specific proteins (Sp1/Sp3) in the basal transcription activity of neurogranin gene.	SP1 SP3	6.32e-06	3	51	2	16677608
Pubmed	Bifunctional properties of peroxisome proliferator-activated receptor gamma1 in KDR gene regulation mediated via interaction with both Sp1 and Sp3.	SP1 SP3	6.32e-06	3	51	2	15111490
Pubmed	Modulation of Bone Morphogenetic Protein (BMP) 2 gene expression by Sp1 transcription factors.	SP1 SP3	6.32e-06	3	51	2	17317039
Pubmed	Sp1 and Sp3 mediate basal and serum-induced expression of human CENP-W.	SP1 SP3	6.32e-06	3	51	2	20180024
Pubmed	In vivo footprinting of the human 11beta-hydroxysteroid dehydrogenase type 2 promoter: evidence for cell-specific regulation by Sp1 and Sp3.	SP1 SP3	6.32e-06	3	51	2	11850421
Pubmed	Transcription factors sp1 and sp3 regulate expression of human extracellular superoxide dismutase in lung fibroblasts.	SP1 SP3	6.32e-06	3	51	2	18314536
Pubmed	Decreased methylation and transcription repressor Sp3 up-regulated human monoamine oxidase (MAO) B expression during Caco-2 differentiation.	SP1 SP3	6.32e-06	3	51	2	12855685
Pubmed	Murine glypican-4 gene structure and expression; Sp1 and Sp3 play a major role in glypican-4 expression in 3T3-F442A cells.	SP1 SP3	6.32e-06	3	51	2	15297147
Pubmed	Accessible chromatin structure permits factors Sp1 and Sp3 to regulate human TGFBI gene expression.	SP1 SP3	6.32e-06	3	51	2	21554857
Pubmed	Sp1 and Sp3 transcription factors mediate trichostatin A-induced and basal expression of extracellular superoxide dismutase.	SP1 SP3	6.32e-06	3	51	2	15451065
Pubmed	Molecular and functional characterization of the murine ldh2 promoter region: Sp-binding GC-box domains are the key cis-elements regulating ldh2 gene expression during spermatogenesis.	SP1 SP3	6.32e-06	3	51	2	18790003
Pubmed	Transcription of human β4-galactosyltransferase 3 is regulated by differential DNA binding of Sp1/Sp3 in SH-SY5Y human neuroblastoma and A549 human lung cancer cell lines.	SP1 SP3	6.32e-06	3	51	2	30561605
Pubmed	Myc represses the p21(WAF1/CIP1) promoter and interacts with Sp1/Sp3.	SP1 SP3	6.32e-06	3	51	2	11274368
Pubmed	Identification of regulatory elements in the human adipose most abundant gene transcript-1 ( apM-1) promoter: role of SP1/SP3 and TNF-alpha as regulatory pathways.	SP1 SP3	6.32e-06	3	51	2	12378384
Pubmed	The t-PA -7351C>T enhancer polymorphism decreases Sp1 and Sp3 protein binding affinity and transcriptional responsiveness to retinoic acid.	SP1 SP3	6.32e-06	3	51	2	15466927
Pubmed	Identification and characterization of three members of the human metallocarboxypeptidase gene family.	CPA6 CPO	6.32e-06	3	51	2	11836249
Pubmed	Oxidative stress regulates vascular endothelial growth factor-A gene transcription through Sp1- and Sp3-dependent activation of two proximal GC-rich promoter elements.	SP1 SP3	6.32e-06	3	51	2	12509426
Pubmed	Angiotensin-converting enzyme inhibitor promotes angiogenesis through Sp1/Sp3-mediated inhibition of notch signaling in male mice.	SP1 SP3	6.32e-06	3	51	2	36759621
Pubmed	Sp1 and Sp3 regulate the basal transcription of receptor activator of nuclear factor kappa B ligand gene in osteoblasts and bone marrow stromal cells.	SP1 SP3	6.32e-06	3	51	2	16052479
Pubmed	Sp1/3 and NF-1 mediate basal transcription of the human P2X1 gene in megakaryoblastic MEG-01 cells.	SP1 SP3	6.32e-06	3	51	2	16529657
Pubmed	Sp1 and Sp3 transcription factors regulate the basal expression of human microsomal epoxide hydrolase (EPHX1) through interaction with the E1b far upstream promoter.	SP1 SP3	6.32e-06	3	51	2	24315822
Pubmed	Sp1 and Sp3 physically interact and co-operate with GABP for the activation of the utrophin promoter.	SP1 SP3	6.32e-06	3	51	2	11237613
Pubmed	Involvement of Sp1 and Sp3 in differential regulation of human NHE3 promoter activity by sodium butyrate and IFN-gamma/TNF-alpha.	SP1 SP3	6.32e-06	3	51	2	17540780
Pubmed	SP1 and SP3 mediate progesterone-dependent induction of the 17beta hydroxysteroid dehydrogenase type 2 gene in human endometrium.	SP1 SP3	6.32e-06	3	51	2	16807381
Pubmed	Predictive value of Sp1/Sp3/FLIP signature for prostate cancer recurrence.	SP1 SP3	6.32e-06	3	51	2	23028678
Pubmed	Sp proteins and Runx2 mediate regulation of matrix gla protein (MGP) expression by parathyroid hormone.	SP1 SP3	6.32e-06	3	51	2	19306294
Pubmed	Evidence that Sp1 positively and Sp3 negatively regulate and androgen does not directly regulate functional tumor suppressor 15-lipoxygenase 2 (15-LOX2) gene expression in normal human prostate epithelial cells.	SP1 SP3	6.32e-06	3	51	2	15247906
Pubmed	Identification of an Sp factor-dependent promoter in GCET, a gene expressed at high levels in germinal center B cells.	SP1 SP3	6.32e-06	3	51	2	15482850
Pubmed	IFN-gamma and TNF-alpha regulate human NHE3 gene expression by modulating the Sp family transcription factors in human intestinal epithelial cell line C2BBe1.	SP1 SP3	6.32e-06	3	51	2	16760259
Pubmed	The expression of lysyl-oxidase gene family members in myeloproliferative neoplasms.	LOXL1 LOXL2	6.32e-06	3	51	2	23494965
Pubmed	Analysis of Sp transcription factors in the postmortem brain of chronic schizophrenia: a pilot study of relationship to negative symptoms.	SP1 SP3	6.32e-06	3	51	2	23540600
Pubmed	Regulation of the poly(ADP-ribose) polymerase-1 gene expression by the transcription factors Sp1 and Sp3 is under the influence of cell density in primary cultured cells.	SP1 SP3	6.32e-06	3	51	2	15777284
Pubmed	Involvement of Sp1/Sp3 in the activation of the GATA-1 erythroid promoter in K562 cells.	SP1 SP3	6.32e-06	3	51	2	18195733
Pubmed	Inhibition of vascular endothelial growth factor expression in HEC1A endometrial cancer cells through interactions of estrogen receptor alpha and Sp3 proteins.	SP1 SP3	6.32e-06	3	51	2	10816575
Pubmed	Specificity protein (Sp) transcription factors Sp1, Sp3 and Sp4 are non-oncogene addiction genes in cancer cells.	SP1 SP3	6.32e-06	3	51	2	26967243
Pubmed	Curcumin decreases specificity protein expression in bladder cancer cells.	SP1 SP3	6.32e-06	3	51	2	18593936
Pubmed	Pharmacologic doses of ascorbic acid repress specificity protein (Sp) transcription factors and Sp-regulated genes in colon cancer cells.	SP1 SP3	6.32e-06	3	51	2	21919647
Pubmed	The HIV-Tat protein interacts with Sp3 transcription factor and inhibits its binding to a distal site of the sod2 promoter in human pulmonary artery endothelial cells.	SP1 SP3	6.32e-06	3	51	2	31863909
Pubmed	Transcriptional regulation of human FE65, a ligand of Alzheimer's disease amyloid precursor protein, by Sp1.	SP1 SP3	6.32e-06	3	51	2	20091743
Pubmed	Regulation of the varicella-zoster virus ORF3 promoter by cellular and viral factors.	SP1 SP3	6.32e-06	3	51	2	23523134
Pubmed	Expression of mucin 3 and mucin 5AC in arthritic synovial tissue.	MUC3B MUC3A	6.32e-06	3	51	2	18163520
Pubmed	Structural and functional characterization of the mouse tescalcin promoter.	SP1 SP3	6.32e-06	3	51	2	20540995
Pubmed	Sp1 and Sp3 are involved in the full transcriptional activity of centromere protein H in human nasopharyngeal carcinoma cells.	SP1 SP3	6.32e-06	3	51	2	22682030
Pubmed	The interaction with Sp1 and reduction in the activity of histone deacetylase 1 are critical for the constitutive gene expression of IL-1 alpha in human melanoma cells.	SP1 SP3	6.32e-06	3	51	2	17906119
Pubmed	A crucial role for the ubiquitously expressed transcription factor Sp1 at early stages of hematopoietic specification.	SP1 SP3	6.32e-06	3	51	2	24850855
Pubmed	HIV-1 Tat regulates the SOD2 basal promoter by altering Sp1/Sp3 binding activity.	SP1 SP3	6.32e-06	3	51	2	15706661
Cytoband	5q33.1	SLC36A1 SLC36A3	3.87e-04	26	51	2	5q33.1
Cytoband	3q24	CPA3 CPB1	5.51e-04	31	51	2	3q24
Cytoband	Ensembl 112 genes in cytogenetic band chr12p13	P3H3 B4GALNT3 TEX52 CD163	6.46e-04	353	51	4	chr12p13
Cytoband	7q22	MUC3B MUC3A	8.29e-04	38	51	2	7q22
Cytoband	Ensembl 112 genes in cytogenetic band chr3q24	CPA3 CPB1	1.27e-03	47	51	2	chr3q24
Cytoband	Ensembl 112 genes in cytogenetic band chr8q13	CPA6 C8orf44	3.27e-03	76	51	2	chr8q13
GeneFamily	Zinc fingers C2H2-type\|Sp transcription factors	SP8 SP1 SP3 SP5	1.15e-09	9	33	4	755
GeneFamily	Carboxypeptidases	CPA6 CPO CPA3 CPB1	5.38e-08	21	33	4	1321
GeneFamily	CD molecules\|Mucins	MUC3B MUC3A	6.64e-04	21	33	2	648
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	SP8 SP1 SP3 SP5 REPIN1	9.19e-03	718	33	5	28
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL12A1 RTL3 P3H3 LOXL1 LOXL2 LAMA2	7.36e-08	191	50	6	75d2197076a9dfc868e8baf95bd4c5e44f438e3e
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL12A1 RTL3 P3H3 LOXL1 LOXL2 LAMA2	7.36e-08	191	50	6	4b50fdd310701251e64e16cd2d07ce03dbfd3e3e
ToppCell	droplet-Fat-Scat-18m-Mesenchymal-Cd34+\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	P3H3 LOXL1 LOXL2 LAMA2 LOXL4 LOXL3	7.83e-08	193	50	6	316ebdf15f75d88c348f909b643fcd315364ca84
ToppCell	droplet-Fat-Scat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	P3H3 LOXL1 LOXL2 LAMA2 LOXL4 LOXL3	7.83e-08	193	50	6	1afdd3f7d703f4204a2cbfe40e135ac7b09213f7
ToppCell	droplet-Fat-Scat-18m-Mesenchymal\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	P3H3 LOXL1 LOXL2 LAMA2 LOXL4 LOXL3	7.83e-08	193	50	6	8dc6db335678f3a5cfd36026ad811fed8d9cb4bc
ToppCell	P07-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	RTL3 P3H3 LOXL1 LAMA2 CPB1	1.98e-06	184	50	5	01257e5c12e38b849fd3d9496c43ded666249ba5
ToppCell	E18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	P3H3 LOXL2 LAMA2 LOXL3 CPEB1	2.20e-06	188	50	5	a906c29e3fda22eecfec3e5cac706c417bf2b7a4
ToppCell	droplet-Lung-LUNG-1m-Mesenchymal-Adventitial_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RTL3 P3H3 LOXL1 LAMA2 LOXL4	2.25e-06	189	50	5	378f26f751ab4b470948c35dd8347de72dd12ff7
ToppCell	droplet-Lung-LUNG-1m-Mesenchymal-adventitial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RTL3 P3H3 LOXL1 LAMA2 LOXL4	2.25e-06	189	50	5	f0a2d4ef9896d764971ebbc6952510c128bb76e8
ToppCell	facs-Skin-nan-18m-Mesenchymal-nan\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CPA6 LOXL1 LOXL2 LAMA2 SP5	2.25e-06	189	50	5	29287525120be2953b76881ba3cfc4379c265e7a
ToppCell	facs-Skin-nan-18m-Mesenchymal-fibroblast\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CPA6 LOXL1 LOXL2 LAMA2 SP5	2.25e-06	189	50	5	7150dad9a92a715487c2d8130fa01b752ea69663
ToppCell	facs-Skin-nan-18m-Mesenchymal\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CPA6 LOXL1 LOXL2 LAMA2 SP5	2.25e-06	189	50	5	6e4c0effd5192fd00052abc048fdb87a74fb6554
ToppCell	E18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	P3H3 LOXL2 LAMA2 LOXL3 CPEB1	2.31e-06	190	50	5	951e067d14412db67dc3babcdf61e41717d7b429
ToppCell	PND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RTL3 P3H3 LOXL1 LOXL2 LAMA2	2.31e-06	190	50	5	947807863a9b247c301c6cf63d6fd5a2c8018e66
ToppCell	PND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RTL3 P3H3 LOXL1 LOXL2 LAMA2	2.37e-06	191	50	5	db4943dd19207663fb9e27f8940fa4b06a933625
ToppCell	facs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	P3H3 LOXL1 LOXL2 LAMA2 LOXL3	2.44e-06	192	50	5	32acd89617934016cd135d2cc797e8e79ae1b37f
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RTL3 P3H3 LOXL1 LOXL2 LAMA2	2.44e-06	192	50	5	ad48c941a3ddfd9a5146bafc2209da577bb50531
ToppCell	facs-Lung-nan-3m-Mesenchymal-Adventitial_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	P3H3 LOXL1 LOXL2 LAMA2 LOXL3	2.44e-06	192	50	5	a2c31390da4962bda9a936470b0b68fa1f5d47d1
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RTL3 P3H3 LOXL1 LOXL2 LAMA2	2.44e-06	192	50	5	19b94f254d51b9bda3d9b7c6f85e27ecb58409c8
ToppCell	facs-Lung-nan-3m-Mesenchymal-adventitial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	P3H3 LOXL1 LOXL2 LAMA2 LOXL3	2.44e-06	192	50	5	eeab1cef7c36ae824381952c5b2c982368c379fd
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-3m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	P3H3 LOXL1 LOXL2 LAMA2 LOXL3	2.44e-06	192	50	5	beac6b3c191b11add8e39e8d04562b478ea8929e
ToppCell	droplet-Bladder-nan-3m\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL12A1 P3H3 LOXL1 LOXL2 LAMA2	2.50e-06	193	50	5	e55f79bad6888b84b0ad5fccded498b170e3c6dc
ToppCell	droplet-Limb_Muscle-nan-3m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	P3H3 LOXL1 LOXL2 LAMA2 LOXL3	2.50e-06	193	50	5	428b1a3ad87dff7f65de5161d40f102572a9341b
ToppCell	droplet-Bladder-nan-3m-Epithelial\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL12A1 P3H3 LOXL1 LOXL2 LAMA2	2.56e-06	194	50	5	b294056f9bdc243263cf36dce7b62564144b9de1
ToppCell	droplet-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	P3H3 LOXL1 LOXL2 LAMA2 LOXL3	2.56e-06	194	50	5	5594f7437448cb4b37d2d100f44d30c4a367df26
ToppCell	facs-SCAT-Fat-3m-Mesenchymal\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	P3H3 LOXL1 LOXL2 LAMA2 LOXL3	2.56e-06	194	50	5	14b614f039bc866a1348a2728a68b7d254c7748c
ToppCell	facs-SCAT-Fat-3m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	P3H3 LOXL1 LOXL2 LAMA2 LOXL3	2.56e-06	194	50	5	68c7bfead1158641928cc276f599b4a79e06c73c
ToppCell	facs-SCAT-Fat-3m-Mesenchymal-mesenchymal_progenitor\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	P3H3 LOXL1 LOXL2 LAMA2 LOXL3	2.56e-06	194	50	5	f6aeae6a1e4017e341323fd4784c9e3bae00552b
ToppCell	Fibroblast-B_(Myofibroblast)\|World / shred on cell class and cell subclass (v4)	COL12A1 P3H3 LOXL1 LOXL2 LOXL3	2.63e-06	195	50	5	a8d6416518f226e1ec2d6bdc9d4b90cef5cb1365
ToppCell	facs-Bladder-nan-3m-Epithelial-bladder_cell\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL12A1 P3H3 LOXL1 LOXL2 LAMA2	2.63e-06	195	50	5	223f5f07dc28fa13a09bb589884c58043c7928c7
ToppCell	droplet-Bladder-nan-3m-Epithelial-bladder_cell\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL12A1 P3H3 LOXL1 LOXL2 LAMA2	2.69e-06	196	50	5	f47e551ba484687ba6ce8c29a085106131364042
ToppCell	PND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL12A1 P3H3 LOXL1 LOXL2 LOXL3	2.76e-06	197	50	5	9d7a1c7dc70ba5e35645f19f9e056e4fa2494aa0
ToppCell	PND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL12A1 P3H3 LOXL1 LOXL2 LOXL3	2.76e-06	197	50	5	090a251194da3e2806989d9a522588f83f52da7f
ToppCell	PND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL12A1 P3H3 LOXL1 LOXL2 LOXL3	2.76e-06	197	50	5	43b5f8e917506c1717f9311584901b506ffd2c79
ToppCell	PND03-Mesenchymal-Mesenchymal_myocytic\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL12A1 P3H3 LOXL1 LOXL2 LOXL3	2.83e-06	198	50	5	b258f672529fb2c03e62e2696d335043c4963280
ToppCell	10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-SMC_COL-F\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	COL12A1 P3H3 LOXL1 LOXL2 B4GALNT3	2.83e-06	198	50	5	eb78b2ae6a787dbc75947e8dd5a03693285bc8be
ToppCell	10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-SMC_COL\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	COL12A1 P3H3 LOXL1 LOXL2 LAMA2	2.83e-06	198	50	5	8b9e8eaeffda40912a0163fdf39b93bc5e64751c
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL12A1 P3H3 LOXL1 LOXL2 LAMA2	2.83e-06	198	50	5	1b90d632e59c3c47b936e829cceeb0334f05f34f
ToppCell	facs-Trachea-nan-3m-Mesenchymal\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	P3H3 LOXL1 LOXL2 LAMA2 LOXL3	2.90e-06	199	50	5	67f78c070c56e44fba36542041bf7fa1c291807c
ToppCell	facs-Trachea-nan-3m-Mesenchymal-nan\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	P3H3 LOXL1 LOXL2 LAMA2 LOXL3	2.90e-06	199	50	5	1ae244b563f85c1ee8d22698f478c842a4d9c7f5
ToppCell	367C-Fibroblasts-Fibroblast-B_(Myofibroblast)\|367C / Donor, Lineage, Cell class and subclass (all cells)	COL12A1 P3H3 LOXL1 LOXL2 LAMA2	2.97e-06	200	50	5	731e55070a7ff315091855bd88cda30e5a7e1a98
ToppCell	367C-Fibroblasts-Fibroblast-B_(Myofibroblast)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	COL12A1 P3H3 LOXL1 LOXL2 LAMA2	2.97e-06	200	50	5	082e718c1da3f4fdd33a001d15ad3ddb2be985c7
ToppCell	3'-GW_trimst-1-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_2_(ZEB2+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL12A1 LOXL1 LOXL2 SP5 LOXL4	2.97e-06	200	50	5	ac8a5d71acd4d401995babd233f0d3738e8ad2a5
ToppCell	(5)_Fibroblast-B_(Myofibroblast)\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	COL12A1 P3H3 LOXL1 LOXL2 LAMA2	2.97e-06	200	50	5	9bbaa666d0f3b4782c1b4b95e0fa5fc1467842d8
ToppCell	distal-mesenchymal-Myofibroblast\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	COL12A1 RTL3 P3H3 LOXL1 LAMA2	2.97e-06	200	50	5	61854a459385cd9295be37157a8f81a2c227dff3
ToppCell	Hippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1\|Hippocampus / BrainAtlas - Mouse McCarroll V32	ENGASE COL12A1 LOXL2 CPB1	1.56e-05	134	50	4	b959899c89d3a0363a3cd2309155280e0fe5ba88
ToppCell	368C-Fibroblasts-Fibroblast-F-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	COL12A1 RTL3 SP5 LOXL3	2.36e-05	149	50	4	9286bc56ff2e245630537a0bda5f1a1e17be863a
ToppCell	368C-Fibroblasts-Fibroblast-F\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	COL12A1 RTL3 SP5 LOXL3	2.36e-05	149	50	4	f53151d9e5e724a61be0ee6a8c740d1990f28d5f
ToppCell	Frontal_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	CPA6 COL12A1 GPR150 B4GALNT3	2.43e-05	150	50	4	9d5bbdca19da60e1a2121ef64ec8e1375a5dbf6d
ToppCell	Frontal_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	CPA6 COL12A1 GPR150 B4GALNT3	2.62e-05	153	50	4	b37a1ecad389d2848b8ca4d287823e8048207420
ToppCell	Thalamus-Endothelial-ENDOTHELIAL_TIP-Dcn_1\|Thalamus / BrainAtlas - Mouse McCarroll V32	ENGASE COL12A1 LOXL1 LOXL2	2.62e-05	153	50	4	e9c6fb5c41adb6595c66c3a917fe455348279e54
ToppCell	Thalamus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1\|Thalamus / BrainAtlas - Mouse McCarroll V32	ENGASE COL12A1 LOXL1 LOXL2	2.62e-05	153	50	4	b8b5ff7d2feea3e3a352fb5530e49f639fe1ff88
ToppCell	Thalamus-Endothelial-ENDOTHELIAL_TIP\|Thalamus / BrainAtlas - Mouse McCarroll V32	ENGASE COL12A1 LOXL1 LOXL2	2.62e-05	153	50	4	2513edfae62a44e51d3556675a096723194c966c
ToppCell	368C-Fibroblasts-Fibroblast-F-\|368C / Donor, Lineage, Cell class and subclass (all cells)	COL12A1 RTL3 SP5 LOXL3	2.90e-05	157	50	4	982e6ea78c7dabdb7c07c4a5fb2425d5e45b5b94
ToppCell	368C-Fibroblasts-Fibroblast-F\|368C / Donor, Lineage, Cell class and subclass (all cells)	COL12A1 RTL3 SP5 LOXL3	2.90e-05	157	50	4	74038192f016f95f80e0189035ee8ccc22ceb1b8
ToppCell	Globus_pallidus-Endothelial-ENDOTHELIAL_TIP-Dcn_1\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	COL12A1 LOXL1 LOXL2 LOXL4	3.52e-05	165	50	4	570483b43ccb5831feec9337b4664814431d40b1
ToppCell	Globus_pallidus-Endothelial-ENDOTHELIAL_TIP\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	COL12A1 LOXL1 LOXL2 LOXL4	3.52e-05	165	50	4	2026a9a07f4d314cc05c167e491312b373468e46
ToppCell	10x5'v1-week_12-13-Myeloid_DC-DC-DC1\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	ATG3 FBXO41 CRIP3 REPIN1	3.87e-05	169	50	4	319511ea57bbd72c2d95e8516d093689df67a912
ToppCell	E17.5-Mesenchymal-mesenchymal_fibroblast-tracheal_fibroblast\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	RTL3 P3H3 LOXL4 LOXL3	3.87e-05	169	50	4	58e22f9119240664515fe91ca53812611a8f17d6
ToppCell	PND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LOXL1 LAMA2 LOXL4 CRIP3	3.87e-05	169	50	4	031465190cd3623a25ef2b868daab8d932c8ff08
ToppCell	PND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LOXL1 LAMA2 LOXL4 CRIP3	4.05e-05	171	50	4	15cb4670ff4234ac46aea8a5911138d6913c4482
ToppCell	facs-Lung-EPCAM-3m-Mesenchymal-adventitial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RTL3 P3H3 LOXL2 LAMA2	4.73e-05	178	50	4	27497dbfcf9bb4dd0bf7caa0bd78c7e85f5c18ee
ToppCell	facs-Lung-EPCAM-3m-Mesenchymal-Adventitial_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RTL3 P3H3 LOXL2 LAMA2	4.73e-05	178	50	4	d348a9550db940d204706529759dc51e30506b5f
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-6_VIP_VIP\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SP8 COL12A1 NKAIN3 RGS12	4.84e-05	179	50	4	01302505816f272243659e20d751b61a198a2fc0
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-6_VIP_VIP\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SP8 COL12A1 NKAIN3 RGS12	4.94e-05	180	50	4	c6030e725e3d86d5d74a1676330c77ffeceb324f
ToppCell	facs-Pancreas-Exocrine-18m-Mesenchymal\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RTL3 LOXL1 LAMA2 LOXL3	5.05e-05	181	50	4	269b39ac65790061d54eab47a8eeb024403f0348
ToppCell	PND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RTL3 P3H3 LOXL1 LAMA2	5.05e-05	181	50	4	6730e249cac55ae892cc567d9211615882f3dab4
ToppCell	facs-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RTL3 LOXL1 LAMA2 LOXL3	5.05e-05	181	50	4	cd4f744b6b64ba6c22ec07afd1d3058a2546909d
ToppCell	PND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RTL3 P3H3 LOXL1 LAMA2	5.05e-05	181	50	4	3462aa1c08fbaf613b6278ab2c7a5a0940bf537d
ToppCell	facs-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RTL3 LOXL1 LAMA2 LOXL3	5.05e-05	181	50	4	c8395ae872aa80b3ae1ab7c53e57b3ca15aeb0e2
ToppCell	10x3'2.3-week_12-13-Mesenchymal_osteo-stroma-chondrocyte\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	COL12A1 RTL3 LOXL2 LOXL4	5.16e-05	182	50	4	ed487f3a774812caa2903a646b60c86edcc1e65e
ToppCell	PND01-03-samps-Mesenchymal-Myofibroblast\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	COL12A1 RTL3 LOXL2 LAMA2	5.16e-05	182	50	4	812dac35b9aa05be48258082e007f6c00e7b4dd8
ToppCell	droplet-Heart-4Chambers-18m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	P3H3 LOXL1 LAMA2 B4GALNT3	5.16e-05	182	50	4	f4b74c2756989812abe4e7055ec8918f69d56025
ToppCell	3'-Child04-06-SmallIntestine-Mesenchymal-fibroblastic-Stromal_4_(MMP1+)\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CPA6 COL12A1 LOXL1 LAMA2	5.27e-05	183	50	4	269afec240a756eec3bbae5f30ec784281af3433
ToppCell	normal_Lung-Fibroblasts-Myofibroblasts\|normal_Lung / Location, Cell class and cell subclass	COL12A1 P3H3 LOXL1 LOXL2	5.38e-05	184	50	4	0b336489c10e8c3c957795dd845454f03404382b
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_VIP_PRSS8\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SP8 COL12A1 LOXL1 RGS12	5.50e-05	185	50	4	4c42bd3cd72f91f4d4ebb849069a03761a2cd662
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Myeloid-Macrophage-macrophage,_alveolar-Macro_c1-C1QC\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	NDUFB2 REPIN1 RABGGTA CD163	5.50e-05	185	50	4	0e8064bb317f26959d3c59b4f73d0c455161ccd7
ToppCell	E17.5-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	P3H3 LOXL1 LAMA2 CPB1	5.50e-05	185	50	4	c85bba1210f1d389add3e40be9b96abac40cf8c1
ToppCell	P03-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	RTL3 P3H3 LOXL1 LAMA2	5.61e-05	186	50	4	c0a036096c2cb23305605b8aaf18869d6e0fb512
ToppCell	droplet-Heart-4Chambers-18m-Mesenchymal-fibroblast\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	P3H3 LOXL1 LAMA2 B4GALNT3	5.61e-05	186	50	4	35c88cc4eb388811fcac4323b549e5897fa8dc27
ToppCell	droplet-Heart-4Chambers-18m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	P3H3 LOXL1 LAMA2 B4GALNT3	5.61e-05	186	50	4	d998c5b00083cf2a7cd5341a98b7374b4de73c63
ToppCell	droplet-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RTL3 LOXL1 LAMA2 LOXL4	5.73e-05	187	50	4	4e553721fa5598cb211f44e3226280b7e6885484
ToppCell	droplet-Pancreas-Exocrine-18m-Mesenchymal\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RTL3 LOXL1 LAMA2 LOXL4	5.73e-05	187	50	4	d36e7fc6125e7a4310499365022d38f34b757a73
ToppCell	droplet-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RTL3 LOXL1 LAMA2 LOXL4	5.73e-05	187	50	4	827eae63fabf6892a82ce7779b5f395958d3d628
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Lobular_Carcinoma-6\|TCGA-Breast / Sample_Type by Project: Shred V9	STARD8 LOXL1 LAMA2 CPA3	5.85e-05	188	50	4	c90669b51e1902fe7726555290c91c92a911df83
ToppCell	facs-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	P3H3 LOXL1 LAMA2 LOXL3	5.85e-05	188	50	4	bba6b273bd47dd0e27fde914e9e6fc9d76fd5176
ToppCell	Fibroblast-C\|World / shred on cell class and cell subclass (v4)	P3H3 LOXL1 LOXL2 LAMA2	5.97e-05	189	50	4	58e0400fbab5a0755504275aef5cf7986149abab
ToppCell	facs-BAT-Fat-18m-Mesenchymal\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LOXL1 LOXL2 LAMA2 LOXL3	5.97e-05	189	50	4	bba28f57a0708515fdd5acd9592dbbe4a4f57116
ToppCell	facs-BAT-Fat-18m-Mesenchymal-mesenchymal_progenitor\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LOXL1 LOXL2 LAMA2 LOXL3	5.97e-05	189	50	4	cf293b23a4c0e8a0c9f09115b1d53d9b11de72e2
ToppCell	facs-BAT-Fat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LOXL1 LOXL2 LAMA2 LOXL3	5.97e-05	189	50	4	87323e86a5b5d159920a07e6bd7ef5e3438cd085
ToppCell	droplet-Mammary_Gland-nan-21m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	P3H3 LOXL1 LOXL2 LAMA2	5.97e-05	189	50	4	bc54ffd7bd1627a36747a80ce5139e4a69928400
ToppCell	droplet-Lung-nan-18m-Mesenchymal-Adventitial_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	P3H3 LOXL1 LAMA2 LOXL3	6.10e-05	190	50	4	97772e69e6f51ebffbb5433ca7b40f1048723220
ToppCell	droplet-Mammary_Gland-nan-3m-Mesenchymal\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	P3H3 LOXL1 LOXL2 LAMA2	6.10e-05	190	50	4	bd0d68dc1b6f388190a6ba8a83b011619abe2bdd
ToppCell	droplet-Mammary_Gland-nan-21m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	P3H3 LOXL1 LOXL2 LAMA2	6.10e-05	190	50	4	f3ca94a31a35eed5fecf3c4b8c957e1bc4150158
ToppCell	droplet-Mammary_Gland-nan-3m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	P3H3 LOXL1 LOXL2 LAMA2	6.10e-05	190	50	4	e275de94468872e70cf305b3b450823d4c9c5e3f
ToppCell	droplet-Lung-nan-18m-Mesenchymal-adventitial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	P3H3 LOXL1 LAMA2 LOXL3	6.10e-05	190	50	4	72c2b824acdc43139e6635785df3ed3feb58ec46
ToppCell	droplet-Mammary_Gland-nan-3m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	P3H3 LOXL1 LOXL2 LAMA2	6.10e-05	190	50	4	ee2f4a55d2fd18b83e55399b5b5697a15a2d2e70
ToppCell	droplet-Mammary_Gland-nan-21m-Mesenchymal\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	P3H3 LOXL1 LOXL2 LAMA2	6.10e-05	190	50	4	c2cd1eb674162ee40502c3380b7245c85079c7ce
ToppCell	facs-Aorta-Heart-18m\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	P3H3 LOXL1 LOXL2 LAMA2	6.22e-05	191	50	4	6242f83acaf1714e9c1771a832cb67674b19e96d
ToppCell	PND07-28-samps-Mesenchymal-Myofibroblast\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	COL12A1 LOXL1 LOXL2 LAMA2	6.22e-05	191	50	4	9bbafdf316c1fa3a9f1ee30d41dd7158b5c97279
Drug	amiguanidine	LOXL1 LOXL2 LOXL4 LOXL3	9.45e-11	5	49	4	CID000364439
Drug	1-benzyl-2-methyl-5-methoxytryptamine	LOXL1 LOXL2 LOXL4 LOXL3	2.83e-10	6	49	4	CID000009925
Drug	BU99006	LOXL1 LOXL2 LOXL4 LOXL3	2.83e-10	6	49	4	CID006603748
Drug	5-hydroxyisatin	LOXL1 LOXL2 LOXL4 LOXL3	2.83e-10	6	49	4	CID010352011
Drug	T 794	LOXL1 LOXL2 LOXL4 LOXL3	2.83e-10	6	49	4	CID003077680
Drug	NSD 2023	LOXL1 LOXL2 LOXL4 LOXL3	2.83e-10	6	49	4	CID000019831
Drug	1-PCPA	LOXL1 LOXL2 LOXL4 LOXL3	2.83e-10	6	49	4	CID000194548
Drug	N-cyclopropyl-5,6-dimethoxytryptamine	LOXL1 LOXL2 LOXL4 LOXL3	2.83e-10	6	49	4	CID000156277
Drug	N-cyclopropyl-6,7-dimethoxytryptamine	LOXL1 LOXL2 LOXL4 LOXL3	2.83e-10	6	49	4	CID000156278
Drug	N-cyclopropyl-alpha-methylbenzylamine	LOXL1 LOXL2 LOXL4 LOXL3	2.83e-10	6	49	4	CID000362778
Drug	dimethylphenethylamine	LOXL1 LOXL2 LOXL4 LOXL3	6.59e-10	7	49	4	CID000025124
Drug	BU 224	LOXL1 LOXL2 LOXL4 LOXL3	6.59e-10	7	49	4	CID000002457
Drug	M 2113	LOXL1 LOXL2 LOXL4 LOXL3	6.59e-10	7	49	4	CID000072895
Drug	N-(2-aminoethyl)benzamide	LOXL1 LOXL2 LOXL4 LOXL3	6.59e-10	7	49	4	CID000423156
Drug	cimoxatone	LOXL1 LOXL2 LOXL4 LOXL3	6.59e-10	7	49	4	CID000052542
Drug	iproclozide	LOXL1 LOXL2 LOXL4 LOXL3	6.59e-10	7	49	4	CID000019063
Drug	brofaromine	LOXL1 LOXL2 LOXL4 LOXL3	6.59e-10	7	49	4	CID000044570
Drug	tetrahydroharmine	LOXL1 LOXL2 LOXL4 LOXL3	6.59e-10	7	49	4	CID000159809
Drug	4'-amino-MPTP	LOXL1 LOXL2 LOXL4 LOXL3	6.59e-10	7	49	4	CID000086263
Drug	4-methoxytranylcypromine	LOXL1 LOXL2 LOXL4 LOXL3	6.59e-10	7	49	4	CID003082143
Drug	1-Phenylcyclobutylamine	LOXL1 LOXL2 LOXL4 LOXL3	6.59e-10	7	49	4	CID000152214
Drug	JB 835	LOXL1 LOXL2 LOXL4 LOXL3	6.59e-10	7	49	4	CID000152988
Drug	1-benzylcyclopropylamine	LOXL1 LOXL2 LOXL4 LOXL3	6.59e-10	7	49	4	CID000152923
Drug	RS-2232	LOXL1 LOXL2 LOXL4 LOXL3	6.59e-10	7	49	4	CID000134882
Drug	SR 95191	LOXL1 LOXL2 LOXL4 LOXL3	6.59e-10	7	49	4	CID000072119
Drug	p-dimethylaminomethylbenzylamine	LOXL1 LOXL2 LOXL4 LOXL3	6.59e-10	7	49	4	CID000193714
Drug	MPTP-3-ol	LOXL1 LOXL2 LOXL4 LOXL3	6.59e-10	7	49	4	CID000100194
Drug	AC1O5VTH	LOXL1 LOXL2 LOXL4 LOXL3	1.32e-09	8	49	4	CID006441710
Drug	AC1Q6B1A	LOXL1 LOXL2 LOXL4 LOXL3	1.32e-09	8	49	4	CID000088562
Drug	4-chlorobenzylamine	LOXL1 LOXL2 LOXL4 LOXL3	1.32e-09	8	49	4	CID000066036
Drug	amezinium	LOXL1 LOXL2 LOXL4 LOXL3	1.32e-09	8	49	4	CID000071926
Drug	mebanazine	LOXL1 LOXL2 LOXL4 LOXL3	1.32e-09	8	49	4	CID000006179
Drug	mofegiline	LOXL1 LOXL2 LOXL4 LOXL3	1.32e-09	8	49	4	CID006437850
Drug	pyrazidol	LOXL1 LOXL2 LOXL4 LOXL3	1.32e-09	8	49	4	CID000068802
Drug	4-fluorotranylcypromine	LOXL1 LOXL2 LOXL4 LOXL3	1.32e-09	8	49	4	CID003082666
Drug	ranbezolid	LOXL1 LOXL2 LOXL4 LOXL3	1.32e-09	8	49	4	CID000496993
Drug	2-propyl-pentylamine	LOXL1 LOXL2 LOXL4 LOXL3	1.32e-09	8	49	4	CID000170419
Drug	Q 192	LOXL1 LOXL2 LOXL4 LOXL3	1.32e-09	8	49	4	CID000077317
Drug	Lilly 51641	LOXL1 LOXL2 LOXL4 LOXL3	2.37e-09	9	49	4	CID000021485
Drug	3-amino-2-oxazolidinone	LOXL1 LOXL2 LOXL4 LOXL3	2.37e-09	9	49	4	CID000065725
Drug	toloxatone	LOXL1 LOXL2 LOXL4 LOXL3	2.37e-09	9	49	4	CID000034521
Drug	MDL 72392	LOXL1 LOXL2 LOXL4 LOXL3	2.37e-09	9	49	4	CID006439254
Drug	AC1L4KA6	LOXL1 LOXL2 LOXL4 LOXL3	2.37e-09	9	49	4	CID000158620
Drug	AC1L1BMC	LOXL1 LOXL2 LOXL4 LOXL3	2.37e-09	9	49	4	CID000001500
Drug	FLA 336	LOXL1 LOXL2 LOXL4 LOXL3	2.37e-09	9	49	4	CID000123706
Drug	RS-8359	LOXL1 LOXL2 LOXL4 LOXL3	2.37e-09	9	49	4	CID000164116
Drug	pinoline	LOXL1 LOXL2 LOXL4 LOXL3	2.37e-09	9	49	4	CID000001868
Drug	Ro 16-6491	LOXL1 LOXL2 LOXL4 LOXL3	2.37e-09	9	49	4	CID000004289
Drug	FLA 365	LOXL1 LOXL2 LOXL4 LOXL3	2.37e-09	9	49	4	CID000072776
Drug	J 508	LOXL1 LOXL2 LOXL4 LOXL3	2.37e-09	9	49	4	CID000155219
Drug	EXP 561	LOXL1 LOXL2 LOXL4 LOXL3	3.94e-09	10	49	4	CID000027696
Drug	U-0521	LOXL1 LOXL2 LOXL4 LOXL3	3.94e-09	10	49	4	CID000021632
Drug	acetylcadaverine	LOXL1 LOXL2 LOXL4 LOXL3	3.94e-09	10	49	4	CID000189087
Drug	Monase	LOXL1 LOXL2 LOXL4 LOXL3	3.94e-09	10	49	4	CID000008366
Drug	3-dimethylamino-1-propyne	LOXL1 LOXL2 LOXL4 LOXL3	3.94e-09	10	49	4	CID000081643
Drug	N-cyclopropylbenzylamine	LOXL1 LOXL2 LOXL4 LOXL3	3.94e-09	10	49	4	CID000025866
Drug	safrazine	LOXL1 LOXL2 LOXL4 LOXL3	3.94e-09	10	49	4	CID000034041
Drug	NmiQ	LOXL1 LOXL2 LOXL4 LOXL3	3.94e-09	10	49	4	CID000019850
Drug	NSC-169892	LOXL1 LOXL2 LOXL4 LOXL3	3.94e-09	10	49	4	CID000043479
Drug	psychogenic	SP3 LOXL1 LOXL2 LOXL4 LOXL3	6.10e-09	31	49	5	CID000006089
Drug	befloxatone	LOXL1 LOXL2 LOXL4 LOXL3	6.18e-09	11	49	4	CID000060824
Drug	4-hydroxy-3-methoxyphenylglycol-piperazine	LOXL1 LOXL2 LOXL4 LOXL3	6.18e-09	11	49	4	CID002723890
Drug	NSC55260	LOXL1 LOXL2 LOXL4 LOXL3	6.18e-09	11	49	4	CID005356351
Drug	Amiflamina	LOXL1 LOXL2 LOXL4 LOXL3	6.18e-09	11	49	4	CID000071221
Drug	FNPA	LOXL1 LOXL2 LOXL4 LOXL3	9.25e-09	12	49	4	CID000093121
Drug	anisylamine	LOXL1 LOXL2 LOXL4 LOXL3	9.25e-09	12	49	4	CID000075452
Drug	2-(2-benzofuranyl)-2-imidazoline	LOXL1 LOXL2 LOXL4 LOXL3	9.25e-09	12	49	4	CID003080926
Drug	AbeAdo	LOXL1 LOXL2 LOXL4 LOXL3	9.25e-09	12	49	4	CID006436013
Drug	kojic amine	LOXL1 LOXL2 LOXL4 LOXL3	9.25e-09	12	49	4	CID000003841
Drug	HLA20	LOXL1 LOXL2 LOXL4 LOXL3	9.25e-09	12	49	4	CID006918819
Drug	tylciprine	LOXL1 LOXL2 LOXL4 LOXL3	9.25e-09	12	49	4	CID000026069
Drug	pheniprazine	LOXL1 LOXL2 LOXL4 LOXL3	9.25e-09	12	49	4	CID000005929
Drug	viloxazine	LOXL1 LOXL2 LOXL4 LOXL3	9.25e-09	12	49	4	CID000005666
Drug	MPDP	LOXL1 LOXL2 LOXL4 LOXL3	9.25e-09	12	49	4	CID000150458
Drug	SKF 64139	LOXL1 LOXL2 LOXL4 LOXL3	1.33e-08	13	49	4	CID000123919
Drug	isocarboxazid	LOXL1 LOXL2 LOXL4 LOXL3	1.86e-08	14	49	4	CID000003759
Drug	kynuramine	LOXL1 LOXL2 LOXL4 LOXL3	1.86e-08	14	49	4	CID000009692
Drug	FMMT	LOXL1 LOXL2 LOXL4 LOXL3	1.86e-08	14	49	4	CID006438682
Drug	MDL 72145	LOXL1 LOXL2 LOXL4 LOXL3	1.86e-08	14	49	4	CID006438383
Drug	benzylhydrazine	LOXL1 LOXL2 LOXL4 LOXL3	1.86e-08	14	49	4	CID000011157
Drug	lazabemide	LOXL1 LOXL2 LOXL4 LOXL3	1.86e-08	14	49	4	CID000071307
Drug	2'CH3-MPTP	LOXL1 LOXL2 LOXL4 LOXL3	1.86e-08	14	49	4	CID000091767
Drug	tetrabenazine	CPA6 LOXL1 LOXL2 LOXL4 LOXL3	2.33e-08	40	49	5	CID000006018
Drug	MFMD	LOXL1 LOXL2 LOXL4 LOXL3	2.54e-08	15	49	4	CID000122302
Drug	milacemide	LOXL1 LOXL2 LOXL4 LOXL3	2.54e-08	15	49	4	CID000053568
Drug	5-hydroxytryptophol	ENGASE LOXL1 LOXL2 LOXL4 LOXL3	3.00e-08	42	49	5	CID000009061
Drug	Ro 41-1049	LOXL1 LOXL2 LOXL4 LOXL3	3.38e-08	16	49	4	CID000005086
Drug	nitecapone	LOXL1 LOXL2 LOXL4 LOXL3	3.38e-08	16	49	4	CID005464105
Drug	methoxytyramine	LOXL1 LOXL2 LOXL4 LOXL3	3.38e-08	16	49	4	CID000068384
Drug	5-methyltryptamine	LOXL1 LOXL2 LOXL4 LOXL3	4.41e-08	17	49	4	CID000015760
Drug	N-desisopropylpropranolol	LOXL1 LOXL2 LOXL4 LOXL3	4.41e-08	17	49	4	CID000159899
Drug	NSC142627	LOXL1 LOXL2 LOXL4 LOXL3	4.41e-08	17	49	4	CID000422254
Drug	alpha-methyltryptamine	LOXL1 LOXL2 LOXL4 LOXL3	4.41e-08	17	49	4	CID000009287
Drug	protriptyline	LOXL1 LOXL2 LOXL4 LOXL3	5.67e-08	18	49	4	CID000004976
Drug	5-methoxyindole-3-acetic acid	LOXL1 LOXL2 LOXL4 LOXL3	5.67e-08	18	49	4	CID000018986
Drug	p-methoxyamphetamine	LOXL1 LOXL2 LOXL4 LOXL3	7.16e-08	19	49	4	CID000031721
Drug	3-hydroxybenzyl	LOXL1 LOXL2 LOXL4 LOXL3	7.16e-08	19	49	4	CID000145655
Drug	norfenefrine	LOXL1 LOXL2 LOXL4 LOXL3	7.16e-08	19	49	4	CID000004538
Drug	4-methylthioamphetamine	LOXL1 LOXL2 LOXL4 LOXL3	7.16e-08	19	49	4	CID000151900
Drug	m-tyramine	LOXL1 LOXL2 LOXL4 LOXL3	7.16e-08	19	49	4	CID000011492
Disease	response to vitamin	P3H3 NKAIN3	6.91e-05	8	47	2	GO_0033273
Disease	myopia (is_implicated_in)	LAMA2 LOXL3	2.94e-04	16	47	2	DOID:11830 (is_implicated_in)
Disease	Antiglaucoma preparations and miotics use measurement	LOXL1 FNBP4	7.88e-04	26	47	2	EFO_0009944
Disease	Hyperglycemia, Postprandial	SP1 CD163	1.05e-03	30	47	2	C1855520
Disease	Hyperglycemia	SP1 CD163	1.05e-03	30	47	2	C0020456
Disease	joint hypermobility measurement	COL12A1 LOXL1	1.27e-03	33	47	2	EFO_0007905
Disease	Bladder Neoplasm	LOXL1 LAMA2 LOXL4	1.45e-03	140	47	3	C0005695
Disease	Malignant neoplasm of urinary bladder	LOXL1 LAMA2 LOXL4	1.48e-03	141	47	3	C0005684
Disease	heart rate response to exercise	MUC3B MUC3A	2.15e-03	43	47	2	EFO_0009184
Disease	left ventricular diastolic function measurement	GIPR SP1	3.37e-03	54	47	2	EFO_0008204
Disease	pyroglutamine measurement	SLC36A1 SLC36A3	3.88e-03	58	47	2	EFO_0005408
Disease	diastolic blood pressure, systolic blood pressure	SP1 LOXL1 CPO LOXL4 RGS12	4.15e-03	670	47	5	EFO_0006335, EFO_0006336
Disease	tuberculosis	PCED1B CPA6 RGS12	4.95e-03	216	47	3	MONDO_0018076
Disease	Nonorganic psychosis	SP8 SP1	5.44e-03	69	47	2	C0349204
Disease	response to ketamine	SCN11A NKAIN3	5.44e-03	69	47	2	EFO_0009748
Disease	diverticular disease	SP8 LOXL1 CPA3	6.32e-03	236	47	3	EFO_0009959

Protein segments in the cluster

Peptide	Gene	Start	Entry
CREHFENHWKGRARW	C8orf44	26	Q96CB5
WPQGFSWSHRAVVHF	B4GALNT3	776	Q6L9W6
RASCPWYLPWHHHVA	GIPR	81	P48546
HAREWIGPAFCQWFV	CPA6	196	Q8N4T0
GIHAREWIAPAFCQW	CPO	106	Q8IVL8
AAGDHLVHHCPTWQW	ATG3	41	Q9NT62
RCALALWHTWAPEHR	P3H3	666	Q8IVL6
SVHRSWWREHGPGCV	NKAIN3	101	Q8N8D7
DFRPKAGRHSWVWHE	LOXL3	591	P58215
FRPKTGRDSWVWHQC	LOXL4	596	Q96JB6
VHGYPVLAWHSARCW	FDPS	36	P14324
PNRPRHTWEWHSCHQ	LOXL1	436	Q08397
FRPKNGRHAWIWHDC	LOXL2	611	Q9Y4K0
HWFSGPRCEVAVHWR	MUC3A	3211	Q02505
HWDGVHWNGRVHRCL	PCED1B	226	Q96HM7
KHWHAREGWECVFCG	LAMA2	1561	P24043
WRWHSCHSRVFIEGH	IQCF5	101	A8MTL0
HAREWVSPAFCQWFV	CPA3	176	P15088
GWDTFCVKWSPHRAA	COL12A1	2216	Q99715
VLRHCFTEWQHWHGA	CCDC191	401	Q8NCU4
VWHVHGLWVCVDNFP	CRIP3	201	Q6Q6R5
CRDWRFVARHPAVWT	FBXO41	576	Q8TF61
FCRSCWHWRHSMEGL	CPEB1	536	Q9BZB8
RGWVRTHCCLEDAWH	ENGASE	446	Q8NFI3
RTHCPDWDSRESWGH	CLK4	6	Q9HAZ1
WDCPARRWGHSECGH	CD163	1006	Q86VB7
HWIHWRCLFSAFRVE	DHX40	576	Q8IX18
HAREWISPAFCQWFV	CPB1	176	P15086
WFSGPRCEVTVHWRA	MUC3B	1126	Q9H195
INCPHISEAEWVRWH	RTL3	426	Q8N8U3
HLRWHTGERPFVCNW	SP5	316	Q6BEB4
ATPKGWSCHWDRDHR	FNBP4	596	Q8N3X1
RVNPKSYGTWHHRCW	RABGGTA	101	Q92696
ACGHLLSVWWRHRPQ	GPR150	251	Q8NGU9
HLRWHTGERPFMCTW	SP1	646	P08047
WPVASFRHPQWTHRG	STARD8	201	Q92502
TCPNTWLRAHAVWGR	SLC36A3	121	Q495N2
HLRWHTGERPFVCNW	SP8	376	Q8IXZ3
HCRRHFPGWVALWLH	REPIN1	61	Q9BWE0
PFRHAWEAGCQAWDT	SUPT20HL2	336	P0C7V6
AFRADGRWHHVCATW	ADGRD2	201	Q7Z7M1
AVLSPGHRQWDCFWH	URGCP	281	Q8TCY9
RWEARHGWTLPAHAS	nan	46	Q8NFD4
RWLPVHVLREWQCGH	RGS12	536	O14924
SSPCSWLRNHAHWGR	SLC36A1	126	Q7Z2H8
HLRWHSGERPFVCNW	SP3	641	Q02447
HTWGFHTWLDVCRLP	TEX52	91	A6NCN8
WRFWHDSEEVLGHFP	NDUFB2	71	O95178
EYRRHWWRCNGPCQH	SPRTN	161	Q9H040
SRGWPLWHEHVPTAC	ZSWIM6	556	Q9HCJ5
PTVSCLRHWHMGDFW	SCN11A	741	Q9UI33
VFCWRHHTNPVGTEW	TYW1	421	Q9NV66