Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	benzodiazepine receptor binding	RIMBP3 RIMBP3C RIMBP3B	1.80e-06	5	114	3	GO:0030156
GeneOntologyMolecularFunction	Notch binding	DNER JAG2 SNED1 NCOR2	1.60e-05	27	114	4	GO:0005112
GeneOntologyBiologicalProcess	head development	SOX1 WHRN SPHK2 GSX1 KIF26A HAP1 DISC1 GRIN2C KDM6B ARID1A CSRNP1 HOXB2 NCOR2 PRDM8 ZNF335 RBPJ SEC16A SMO ULK1 STRA6 SLC23A1	2.84e-08	919	114	21	GO:0060322
GeneOntologyBiologicalProcess	brain development	SOX1 WHRN SPHK2 GSX1 KIF26A HAP1 DISC1 GRIN2C KDM6B ARID1A HOXB2 NCOR2 PRDM8 ZNF335 RBPJ SEC16A SMO ULK1 SLC23A1	2.35e-07	859	114	19	GO:0007420
GeneOntologyBiologicalProcess	central nervous system development	SOX1 WHRN SPHK2 GSX1 KIF26A HAP1 DISC1 GRIN2C KDM6B ARID1A SOX13 HOXB2 NCOR2 PRDM8 ZNF335 RBPJ SEC16A SMO ULK1 SLC23A1	8.31e-06	1197	114	20	GO:0007417
GeneOntologyBiologicalProcess	forebrain development	SOX1 GSX1 KIF26A HAP1 DISC1 KDM6B ARID1A NCOR2 PRDM8 ZNF335 RBPJ SMO	1.70e-05	489	114	12	GO:0030900
GeneOntologyBiologicalProcess	neuromuscular synaptic transmission	CHAT RIMBP3 RIMBP3C RIMBP3B	4.55e-05	36	114	4	GO:0007274
GeneOntologyBiologicalProcess	mechanosensory behavior	GFI1 DCANP1 STRA6	1.06e-04	17	114	3	GO:0007638
GeneOntologyCellularComponent	histone locus body	ICE1 ELL	1.70e-04	4	112	2	GO:0035363
Domain	Fol_N	DNER SNED1 FCGBP AGRN	3.64e-07	11	110	4	IPR003645
Domain	FOLN	DNER SNED1 FCGBP AGRN	3.64e-07	11	110	4	SM00274
Domain	EGF	NID2 TMEM8B ADAM15 DNER SVEP1 JAG2 SNED1 FCGBP AGRN	1.05e-05	235	110	9	SM00181
Domain	hEGF	DNER SVEP1 JAG2 SNED1	2.09e-05	28	110	4	PF12661
Domain	EGF_3	NID2 TMEM8B ADAM15 DNER SVEP1 JAG2 SNED1 AGRN	7.58e-05	235	110	8	PS50026
Domain	EGF_CA	NID2 DNER SVEP1 JAG2 SNED1 AGRN	8.45e-05	122	110	6	SM00179
Domain	EGF-like_Ca-bd_dom	NID2 DNER SVEP1 JAG2 SNED1 AGRN	9.25e-05	124	110	6	IPR001881
Domain	EGF	NID2 DNER SVEP1 JAG2 SNED1 AGRN	1.01e-04	126	110	6	PF00008
Domain	Xan_ur_permease	SLC23A1 SLC23A3	1.03e-04	3	110	2	PF00860
Domain	Xant/urac/vitC	SLC23A1 SLC23A3	1.03e-04	3	110	2	IPR006043
Domain	RTT107_BRCT_5	MDC1 PAXIP1	1.03e-04	3	110	2	PF16770
Domain	EGF-like_dom	NID2 ADAM15 DNER SVEP1 JAG2 SNED1 FCGBP AGRN	1.13e-04	249	110	8	IPR000742
Domain	EGF-like_CS	NID2 TMEM8B ADAM15 DNER SVEP1 JAG2 SNED1 AGRN	1.57e-04	261	110	8	IPR013032
Domain	EGF_2	NID2 TMEM8B ADAM15 DNER SVEP1 JAG2 SNED1 AGRN	1.74e-04	265	110	8	PS01186
Domain	VWC_out	MUC19 JAG2 FCGBP	1.80e-04	19	110	3	SM00215
Domain	DUF2476	PRR23A PRR23B	2.05e-04	4	110	2	PF10630
Domain	PRR23	PRR23A PRR23B	2.05e-04	4	110	2	IPR018903
Domain	EGF_Ca-bd_CS	NID2 DNER SVEP1 JAG2 SNED1	2.71e-04	97	110	5	IPR018097
Domain	EGF_CA	NID2 DNER SVEP1 JAG2 SNED1	2.98e-04	99	110	5	PS01187
Domain	ASX_HYDROXYL	NID2 DNER SVEP1 JAG2 SNED1	3.12e-04	100	110	5	PS00010
Domain	Growth_fac_rcpt_	NID2 DNER SVEP1 JAG2 IGFBP4 ELAPOR1	3.23e-04	156	110	6	IPR009030
Domain	NIDO_dom	NID2 SNED1	3.40e-04	5	110	2	IPR003886
Domain	NUT	NUTM2A NUTM2B	3.40e-04	5	110	2	IPR024310
Domain	NUT_N	NUTM2A NUTM2B	3.40e-04	5	110	2	IPR024309
Domain	NIDO	NID2 SNED1	3.40e-04	5	110	2	SM00539
Domain	NIDO	NID2 SNED1	3.40e-04	5	110	2	PF06119
Domain	NUT	NUTM2A NUTM2B	3.40e-04	5	110	2	PF12881
Domain	NIDO	NID2 SNED1	3.40e-04	5	110	2	PS51220
Domain	EGF-type_Asp/Asn_hydroxyl_site	NID2 DNER SVEP1 JAG2 SNED1	4.09e-04	106	110	5	IPR000152
Domain	EGF_extracell	ADAM15 DNER SVEP1 JAG2	4.31e-04	60	110	4	IPR013111
Domain	EGF_2	ADAM15 DNER SVEP1 JAG2	4.31e-04	60	110	4	PF07974
Domain	EGF_1	TMEM8B ADAM15 DNER SVEP1 JAG2 SNED1 AGRN	7.85e-04	255	110	7	PS00022
Domain	TIG	RELB RBPJ EBF4	7.92e-04	31	110	3	PF01833
Domain	IPT	RELB RBPJ EBF4	8.71e-04	32	110	3	IPR002909
Domain	VWC	MUC19 JAG2 FCGBP	1.44e-03	38	110	3	SM00214
Domain	PTX	NPTX2 SVEP1	1.50e-03	10	110	2	SM00159
Domain	Pentaxin-related	NPTX2 SVEP1	1.83e-03	11	110	2	IPR001759
Domain	-	NID2 SVEP1	1.83e-03	11	110	2	2.40.155.10
Domain	GFP-like	NID2 SVEP1	1.83e-03	11	110	2	IPR023413
Domain	Pentaxin	NPTX2 SVEP1	1.83e-03	11	110	2	PF00354
Domain	VWF_dom	MUC19 JAG2 FCGBP	1.93e-03	42	110	3	IPR001007
Domain	TIL	MUC19 FCGBP	2.18e-03	12	110	2	PF01826
Domain	C8	MUC19 FCGBP	2.18e-03	12	110	2	PF08742
Domain	Unchr_dom_Cys-rich	MUC19 FCGBP	2.57e-03	13	110	2	IPR014853
Domain	C8	MUC19 FCGBP	2.57e-03	13	110	2	SM00832
Domain	TIL_dom	MUC19 FCGBP	2.99e-03	14	110	2	IPR002919
Domain	VWD	MUC19 FCGBP	3.91e-03	16	110	2	SM00216
Domain	VWF_type-D	MUC19 FCGBP	3.91e-03	16	110	2	IPR001846
Domain	VWFD	MUC19 FCGBP	3.91e-03	16	110	2	PS51233
Domain	VWD	MUC19 FCGBP	3.91e-03	16	110	2	PF00094
Domain	CCP	SVEP1 SNED1 CSMD1	3.96e-03	54	110	3	SM00032
Domain	SUSHI	SVEP1 SNED1 CSMD1	4.39e-03	56	110	3	PS50923
Domain	TY	NID2 IGFBP4	4.41e-03	17	110	2	SM00211
Domain	-	NID2 IGFBP4	4.41e-03	17	110	2	4.10.800.10
Domain	THYROGLOBULIN_1_2	NID2 IGFBP4	4.41e-03	17	110	2	PS51162
Domain	Thyroglobulin_1	NID2 IGFBP4	4.41e-03	17	110	2	IPR000716
Domain	Thyroglobulin_1	NID2 IGFBP4	4.41e-03	17	110	2	PF00086
Domain	THYROGLOBULIN_1_1	NID2 IGFBP4	4.41e-03	17	110	2	PS00484
Domain	Sushi_SCR_CCP_dom	SVEP1 SNED1 CSMD1	4.62e-03	57	110	3	IPR000436
Domain	BRCT	MDC1 PAXIP1	5.51e-03	19	110	2	PF00533
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	SEMA6C COL4A5 SPHK2 KIF26A TMEM8B OBSCN RELB ICE1 KDM6B ARID1A LARS2 PHC2 JAG2 NCOR2 CYREN PLEKHM2 PLA2G4B ZNF335 SEC16A PAXIP1 ULK1 AGRN ELL	2.79e-12	1105	118	23	35748872
Pubmed	Early inhibition of IL-1β expression by IFN-γ is mediated by impaired binding of NF-κB to the IL-1β promoter but is independent of nitric oxide.	RELB SOCS1 NOS2	1.52e-07	4	118	3	23667107
Pubmed	RIM-BP3 is a manchette-associated protein essential for spermiogenesis.	RIMBP3 RIMBP3C RIMBP3B	1.52e-07	4	118	3	19091768
Pubmed	Structure and evolution of RIM-BP genes: identification of a novel family member.	RIMBP3 RIMBP3C RIMBP3B	3.79e-07	5	118	3	17855024
Pubmed	Interaction network of human early embryonic transcription factors.	ZNF703 BCORL1 ARID1A SOX13 ZNF512B NCOR2 MDC1 SEC16A PAXIP1	3.34e-06	351	118	9	38297188
Pubmed	Identification and functional characterization of transcriptional activators in human cells.	ZNF703 BCORL1 ARID1A HOXB2 NCOR2 RBPJ DYRK1B SEC16A PAXIP1	9.17e-06	398	118	9	35016035
Pubmed	GFI1 promotes the proliferation and migration of esophageal squamous cell carcinoma cells through the inhibition of SOCS1 expression.	GFI1 SOCS1	1.14e-05	2	118	2	34368875
Pubmed	Agrin promotes synaptic differentiation by counteracting an inhibitory effect of neurotransmitter.	CHAT AGRN	1.14e-05	2	118	2	16043708
Pubmed	Loss of the SMRT/NCoR2 corepressor correlates with JAG2 overexpression in multiple myeloma.	JAG2 NCOR2	1.14e-05	2	118	2	19417136
Pubmed	Notch-effector CSL promotes squamous cell carcinoma by repressing histone demethylase KDM6B.	KDM6B RBPJ	1.14e-05	2	118	2	29757189
Pubmed	Gfi-1 is the transcriptional repressor of SOCS1 in acute myeloid leukemia cells.	GFI1 SOCS1	1.14e-05	2	118	2	24018353
Pubmed	OPTHiS Identifies the Molecular Basis of the Direct Interaction between CSL and SMRT Corepressor.	NCOR2 RBPJ	1.14e-05	2	118	2	30157580
Pubmed	Integrative characterization of germ cell-specific genes from mouse spermatocyte UniGene library.	RIMBP3 RIMBP3C RIMBP3B	1.35e-05	14	118	3	17662146
Pubmed	Combined identification of ARID1A, CSMD1, and SENP3 as effective prognostic biomarkers for hepatocellular carcinoma.	ARID1A CSMD1	3.42e-05	3	118	2	33558447
Pubmed	DYRK1B as therapeutic target in Hedgehog/GLI-dependent cancer cells with Smoothened inhibitor resistance.	DYRK1B SMO	3.42e-05	3	118	2	26784250
Pubmed	EBV nuclear antigen EBNALP dismisses transcription repressors NCoR and RBPJ from enhancers and EBNA2 increases NCoR-deficient RBPJ DNA binding.	NCOR2 RBPJ	3.42e-05	3	118	2	21518914
Pubmed	Hypoxia but not normoxia promotes Smoothened transcription through upregulation of RBPJ and Mastermind-like 3 in pancreatic cancer.	RBPJ SMO	3.42e-05	3	118	2	26655998
Pubmed	The clinical phenotype of YWHAE-NUTM2B/E positive pediatric clear cell sarcoma of the kidney.	NUTM2E NUTM2B	3.42e-05	3	118	2	26542179
Pubmed	The clinicopathologic features of YWHAE-FAM22 endometrial stromal sarcomas: a histologically high-grade and clinically aggressive tumor.	NUTM2A NUTM2B	3.42e-05	3	118	2	22456610
Pubmed	FoxP1 orchestration of ASD-relevant signaling pathways in the striatum.	CDS1 DNER KCNT1	5.59e-05	22	118	3	26494785
Pubmed	The little elongation complex functions at initiation and elongation phases of snRNA gene transcription.	ICE1 ELL	6.82e-05	4	118	2	23932780
Pubmed	Wnt5a controls Notch1 signaling through CaMKII-mediated degradation of the SMRT corepressor protein.	NCOR2 RBPJ	6.82e-05	4	118	2	22888005
Pubmed	p53 represses the transcription of snRNA genes by preventing the formation of little elongation complex.	ICE1 ELL	6.82e-05	4	118	2	27268141
Pubmed	SKIP, a CBF1-associated protein, interacts with the ankyrin repeat domain of NotchIC To facilitate NotchIC function.	NCOR2 RBPJ	6.82e-05	4	118	2	10713164
Pubmed	Arid1a-Plagl1-Hh signaling is indispensable for differentiation-associated cell cycle arrest of tooth root progenitors.	ARID1A SMO	6.82e-05	4	118	2	33826897
Pubmed	Nuclear localization of CBF1 is regulated by interactions with the SMRT corepressor complex.	NCOR2 RBPJ	1.13e-04	5	118	2	11509665
Pubmed	Isolation of a novel histone deacetylase reveals that class I and class II deacetylases promote SMRT-mediated repression.	NCOR2 RBPJ	1.13e-04	5	118	2	10640276
Pubmed	3D Modeling of Esophageal Development using Human PSC-Derived Basal Progenitors Reveals a Critical Role for Notch Signaling.	JAG2 RBPJ	1.13e-04	5	118	2	30244870
Pubmed	Substantia nigra dopaminergic neurons and striatal interneurons are engaged in three parallel but interdependent postnatal neurotrophic circuits.	CHAT SMO	1.13e-04	5	118	2	30058223
Pubmed	Ataxin-1 and Brother of ataxin-1 are components of the Notch signalling pathway.	NCOR2 RBPJ	1.13e-04	5	118	2	21475249
Pubmed	A role for the Cajal-body-associated SUMO isopeptidase USPL1 in snRNA transcription mediated by RNA polymerase II.	ICE1 ELL	1.13e-04	5	118	2	24413172
Pubmed	ZNF703 gene amplification at 8p12 specifies luminal B breast cancer.	ZNF703 NCOR2	1.13e-04	5	118	2	21328542
Pubmed	The Noncanonical Role of ULK/ATG1 in ER-to-Golgi Trafficking Is Essential for Cellular Homeostasis.	SEC16A ULK1	1.13e-04	5	118	2	27203176
Pubmed	Basement membrane assembly of the integrin α8β1 ligand nephronectin requires Fraser syndrome-associated proteins.	COL4A5 NID2 AGRN	1.30e-04	29	118	3	22613833
Pubmed	Polymorphisms in genes involved in neurodevelopment may be associated with altered brain morphology in schizophrenia: preliminary evidence.	SEMA6C ADAM15 JAG2	1.45e-04	30	118	3	19054571
Pubmed	Transcriptome-based systematic identification of extracellular matrix proteins.	COL4A5 NID2 AGRN ADAMTSL4	1.55e-04	79	118	4	18757743
Pubmed	Phosphorylation of microtubule-associated protein tau by AMPK-related kinases.	SIK1 BRSK1	1.70e-04	6	118	2	21985311
Pubmed	A synaptic nidogen: developmental regulation and role of nidogen-2 at the neuromuscular junction.	COL4A5 NID2	1.70e-04	6	118	2	18817539
Pubmed	The origin of the ankyrin repeat region in Notch intracellular domains is critical for regulation of HES promoter activity.	NCOR2 RBPJ	1.70e-04	6	118	2	11404076
Pubmed	Dopaminergic co-transmission with sonic hedgehog inhibits abnormal involuntary movements in models of Parkinson's disease and L-Dopa induced dyskinesia.	CHAT SMO	1.70e-04	6	118	2	34552196
Pubmed	SAD kinases control the maturation of nerve terminals in the mammalian peripheral and central nervous systems.	CHAT BRSK1	1.70e-04	6	118	2	24395778
Pubmed	NPTX2 is a key component in the regulation of anxiety.	SOX1 NPTX2	1.70e-04	6	118	2	29844474
Pubmed	Human immunodeficiency virus type 1 Tat protein stimulates inducible nitric oxide synthase expression and nitric oxide production in microglial cultures.	RELB NOS2	1.70e-04	6	118	2	10446807
Pubmed	Genome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan.	GSX1 ME3 NCOR2 CSMD1	2.06e-04	85	118	4	23648065
Pubmed	Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.	NID2 ADAM15 SVEP1 IGFBP4 AGRN ADAMTSL4	2.09e-04	248	118	6	24006456
Pubmed	FKBP8 cell-autonomously controls neural tube patterning through a Gli2- and Kif3a-dependent mechanism.	SOX1 SMO ELL	2.11e-04	34	118	3	18590716
Pubmed	Expression profiling and differential screening between hepatoblastomas and the corresponding normal livers: identification of high expression of the PLK1 oncogene as a poor-prognostic indicator of hepatoblastomas.	ACBD4 CREB3L3 ZNF513	2.11e-04	34	118	3	15221005
Pubmed	A role for SKIP in EBNA2 activation of CBF1-repressed promoters.	NCOR2 RBPJ	2.37e-04	7	118	2	10644367
Pubmed	Disruption of Krox-20 results in alteration of rhombomeres 3 and 5 in the developing hindbrain.	CHAT HOXB2	2.37e-04	7	118	2	7903221
Pubmed	ARID1A orchestrates SWI/SNF-mediated sequential binding of transcription factors with ARID1A loss driving pre-memory B cell fate and lymphomagenesis.	ARID1A IGHG1	2.37e-04	7	118	2	38458187
Pubmed	Cloning and expression analysis of the mouse stroma marker Snep encoding a novel nidogen domain protein.	NID2 SNED1	2.37e-04	7	118	2	15162516
Pubmed	Parent stem cells can serve as niches for their daughter cells.	JAG2 RBPJ	2.37e-04	7	118	2	26147083
Pubmed	The Cofilin/Limk1 Pathway Controls the Growth Rate of Both Developing and Regenerating Motor Axons.	CHAT LIMK1	2.37e-04	7	118	2	31578231
Pubmed	A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.	NUDT18 HAP1 TMEM8B GFI1 PHC2 JAG2 NUTM2B CREB3L3 AGRN	2.37e-04	608	118	9	16713569
Pubmed	PRMT5 interacts with the BCL6 oncoprotein and is required for germinal center formation and lymphoma cell survival.	NCOR2 IGHG1	3.15e-04	8	118	2	30082494
Pubmed	JANEX-1, a JAK3 inhibitor, protects pancreatic islets from cytokine toxicity through downregulation of NF-kappaB activation and the JAK/STAT pathway.	SOCS1 NOS2	3.15e-04	8	118	2	19414010
Pubmed	Transcription factors of the alternative NF-κB pathway are required for germinal center B-cell development.	RELB IGHG1	3.15e-04	8	118	2	27457956
Pubmed	Genome-wide scan of 500,000 single-nucleotide polymorphisms among responders and nonresponders to interferon beta therapy in multiple sclerosis.	OAS3 NOS2	3.15e-04	8	118	2	19667218
Pubmed	Nitric oxide inhibits HIV tat-induced NF-kappaB activation.	RELB NOS2	3.15e-04	8	118	2	10393859
Pubmed	Progenitor cell proliferation in the retina is dependent on Notch-independent Sonic hedgehog/Hes1 activity.	RBPJ SMO	3.15e-04	8	118	2	19124651
Pubmed	Neurotransmitter acetylcholine negatively regulates neuromuscular synapse formation by a Cdk5-dependent mechanism.	CHAT AGRN	3.15e-04	8	118	2	15944126
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	ZNF703 PARG BCORL1 PHC2 ZNF512B RBPJ DYRK1B SEC16A PAXIP1	3.65e-04	645	118	9	25281560
Pubmed	Matching SOX: partner proteins and co-factors of the SOX family of transcriptional regulators.	SOX1 SOX13	4.05e-04	9	118	2	12100890
Pubmed	Mesothelial mobilization in the developing lung and heart differs in timing, quantity, and pathway dependency.	RBPJ SMO	4.05e-04	9	118	2	30702346
Pubmed	Combinatorial CRISPR screen identifies fitness effects of gene paralogues.	CDS1 PARG ARID1A LIMK1 ELL	4.45e-04	186	118	5	33637726
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SEMA6C KIF26A ICE1 KDM6B HEPH ZNF512B MDC1 KCNT1	4.61e-04	529	118	8	14621295
Pubmed	Pro-inflammatory and pro-oxidant properties of the HIV protein Tat in a microglial cell line: attenuation by 17 beta-estradiol.	RELB NOS2	5.05e-04	10	118	2	11579140
Pubmed	A piggyBac insertion disrupts Foxl2 expression that mimics BPES syndrome in mice.	PRR23A PRR23B	5.05e-04	10	118	2	24565867
Pubmed	Human immunodeficiency virus type 1 (HIV-1) tat induces nitric-oxide synthase in human astroglia.	RELB NOS2	5.05e-04	10	118	2	12167619
Pubmed	From head to toes: the multiple facets of Sox proteins.	SOX1 SOX13	5.05e-04	10	118	2	10037800
Pubmed	Identification of Embryonic Neural Plate Border Stem Cells and Their Generation by Direct Reprogramming from Adult Human Blood Cells.	SOX1 HOXB2	5.05e-04	10	118	2	30581079
Pubmed	HiPLA: High-throughput imaging proximity ligation assay.	NCOR2 MDC1 RBPJ	5.20e-04	46	118	3	30419336
Pubmed	Direct regulation of Gata3 expression determines the T helper differentiation potential of Notch.	IGHG1 RBPJ	6.15e-04	11	118	2	17658279
Pubmed	MicroRNA-directed pathway discovery elucidates an miR-221/222-mediated regulatory circuit in class switch recombination.	ARID1A IGHG1	6.15e-04	11	118	2	34586363
Pubmed	Loss of nidogen-1 and -2 results in syndactyly and changes in limb development.	NID2 AGRN	6.15e-04	11	118	2	17023412
Pubmed	Genomic analysis of mouse retinal development.	NUDT18 CDS1 PHC2 NCOR2 PRDM8 PLA2G4B RBPJ ULK1 AGRN PIK3R5 EBF4	6.44e-04	1006	118	11	15226823
Pubmed	Brg1 plays an essential role in development and homeostasis of the duodenum through regulation of Notch signaling.	GFI1 JAG2 RBPJ	6.64e-04	50	118	3	27510977
Pubmed	Spatiotemporal regulation of GLI target genes in the mammalian limb bud.	WHRN PPDPF SVEP1 NCOR2 SMO	7.22e-04	207	118	5	26238476
Pubmed	On and off retinal circuit assembly by divergent molecular mechanisms.	SEMA6C CHAT	7.37e-04	12	118	2	24179230
Pubmed	The little elongation complex regulates small nuclear RNA transcription.	ICE1 ELL	7.37e-04	12	118	2	22195968
Pubmed	Developmental expression of the Notch signaling pathway genes during mouse preimplantation development.	JAG2 RBPJ	7.37e-04	12	118	2	15465494
Pubmed	Compound genetic ablation of nidogen 1 and 2 causes basement membrane defects and perinatal lethality in mice.	COL4A5 NID2	7.37e-04	12	118	2	16024816
Pubmed	Proteomic-based detection of a protein cluster dysregulated during cardiovascular development identifies biomarkers of congenital heart defects.	ADAM15 SLC23A1	7.37e-04	12	118	2	19156209
Pubmed	Interaction of PDK1 with phosphoinositides is essential for neuronal differentiation but dispensable for neuronal survival.	PDPK2P BRSK1	7.37e-04	12	118	2	23275438
Pubmed	An atlas of combinatorial transcriptional regulation in mouse and man.	GSX1 TAF1C POU2AF1 RELB GFI1 ZNF512B NCOR2 ELL EBF4 ZNF513	8.31e-04	877	118	10	20211142
Pubmed	An improved smaller biotin ligase for BioID proximity labeling.	ZNF703 MUC19 ARID1A MDC1	8.38e-04	123	118	4	26912792
Pubmed	Seven new members of the Sox gene family expressed during mouse development.	SOX1 SOX13	8.69e-04	13	118	2	8441686
Pubmed	Cortical and Clonal Contribution of Tbr2 Expressing Progenitors in the Developing Mouse Brain.	SOX1 CHAT	8.69e-04	13	118	2	24927931
Pubmed	Differential effects of spinal motor neuron-derived and skeletal muscle-derived Rspo2 on acetylcholine receptor clustering at the neuromuscular junction.	CHAT AGRN	8.69e-04	13	118	2	30206360
Pubmed	A conserved role for Notch signaling in priming the cellular response to Shh through ciliary localisation of the key Shh transducer Smo.	RBPJ SMO	8.69e-04	13	118	2	25995356
Pubmed	Twenty pairs of sox: extent, homology, and nomenclature of the mouse and human sox transcription factor gene families.	SOX1 SOX13	8.69e-04	13	118	2	12194848
Pubmed	Acetylcholine negatively regulates development of the neuromuscular junction through distinct cellular mechanisms.	CHAT AGRN	8.69e-04	13	118	2	20498043
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	ZNF703 BCORL1 ARID1A SOX13 RIMBP3 NCOR2 RBPJ SEC16A	9.16e-04	588	118	8	38580884
Pubmed	Roles of neurotransmitter in synapse formation: development of neuromuscular junctions lacking choline acetyltransferase.	CHAT AGRN	1.01e-03	14	118	2	12441053
Pubmed	Molecular Profiling of the Developing Lacrimal Gland Reveals Putative Role of Notch Signaling in Branching Morphogenesis.	JAG2 RBPJ	1.01e-03	14	118	2	28192800
Pubmed	Lack of Fgf18 causes abnormal clustering of motor nerve terminals at the neuromuscular junction with reduced acetylcholine receptor clusters.	CHAT AGRN	1.01e-03	14	118	2	29323161
Pubmed	Neuronal subtype-specific genes that control corticospinal motor neuron development in vivo.	ZNF703 IGFBP4	1.01e-03	14	118	2	15664173
Pubmed	Notch3-Jagged signaling controls the pool of undifferentiated airway progenitors.	JAG2 RBPJ	1.01e-03	14	118	2	25564622
Pubmed	Origin and molecular specification of striatal interneurons.	CHAT NOS2	1.16e-03	15	118	2	10934256
Pubmed	Huntingtin functions as a scaffold for selective macroautophagy.	HAP1 ULK1	1.16e-03	15	118	2	25686248
Interaction	TOP3B interactions	SEMA6C COL4A5 SPHK2 KIF26A TMEM8B OBSCN RELB ICE1 KDM6B ARID1A LARS2 PHC2 JAG2 NCOR2 CYREN PLEKHM2 PLA2G4B ZNF335 MDC1 SEC16A PAXIP1 ULK1 AGRN ADAMTSL4 ELL	3.80e-07	1470	112	25	int:TOP3B
Cytoband	22q11.21	KLHL22 RIMBP3 RIMBP3C RIMBP3B	2.01e-04	111	118	4	22q11.21
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	SVEP1 SNED1 CSMD1	7.31e-04	57	56	3	1179
GeneFamily	SRY-boxes	SOX1 SOX13	1.56e-03	19	56	2	757
Coexpression	HATADA_METHYLATED_IN_LUNG_CANCER_UP	SOX1 NID2 POU2AF1 ME3 PRDM8 IGFBP4 DYRK1B CSMD1 ADAMTSL4 PIK3R5 ZNF513	1.14e-06	377	118	11	M19508
Coexpression	GSE13485_DAY3_VS_DAY21_YF17D_VACCINE_PBMC_UP	SIK1 OAS3 NCOR2 LPP PAXIP1 ULK1 KIF13A PIK3R5	2.74e-06	193	118	8	M3303
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Epithelial-basal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF703 GJB4 SIK1 KDM6B LARS2 JAG2 CSRNP1 NCOR2 SOCS1	2.22e-09	191	118	9	2f733d510a4862565a817f59829d8387d7ea26d9
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Epithelial-basal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF703 GJB4 SIK1 KDM6B LARS2 JAG2 CSRNP1 NCOR2 SOCS1	2.22e-09	191	118	9	8691eba35793e4e90f93d50c2145847ee51289f7
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF703 SIK1 KDM6B LARS2 JAG2 CSRNP1 NCOR2	6.60e-07	186	118	7	bd1185592aedebccd1007dbf2dd2f549fcdf9f42
ToppCell	Severe-B_naive-13\|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)	DDN KDM6B CSRNP1 SOCS1 PROB1 SLC23A3	6.71e-07	116	118	6	f81a7c3e9cbf39124232d98e2a3a3e308137f391
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Epithelial\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF703 SIK1 KDM6B LARS2 JAG2 CSRNP1 NCOR2	7.35e-07	189	118	7	965e0e388251e7318f8b463816dc96ccb4658677
ToppCell	Severe-B_naive-13\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	DDN KDM6B CSRNP1 SOCS1 PROB1 SLC23A3	8.20e-07	120	118	6	d08edc09de8497714af55a6ca08a447cd71095e7
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_artery-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ADAM15 MUC19 SOX13 JAG2 CSRNP1 IGFBP4	6.61e-06	172	118	6	de9b11ab109d04937186c09772cec9105a935f95
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_artery\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	KIF26A ADAM15 MUC19 SOX13 JAG2 IGFBP4	7.79e-06	177	118	6	5ff8dcfb030312126695d53a026d2e104a401b83
ToppCell	356C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	GFI1 PRDM8 FCGBP LRRC26 ELAPOR1 SMO	7.79e-06	177	118	6	709235694cc711b9b79690e23c94577b2ae06811
ToppCell	facs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l6-17\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RAP1GAP HAP1 HEPH ELAPOR1 SLC23A1 KCNT1	7.79e-06	177	118	6	8abdf1d970b2f15e17e185f3e612dd5065c88757
ToppCell	356C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	GFI1 PRDM8 FCGBP LRRC26 ELAPOR1 SMO	7.79e-06	177	118	6	7f9c2a45a994b32f15e5693f7cb873716a4eb568
ToppCell	droplet-Large_Intestine-COLON:P+D-30m-Epithelial-large_intestine_goblet_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RAP1GAP KIF26A GFI1 FCGBP LRRC26 ELAPOR1	9.42e-06	183	118	6	ee9c88be88221b7ad4ea9f890b17d6156fb3432e
ToppCell	droplet-Large_Intestine-COLON:P+D-30m-Epithelial-Goblet_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RAP1GAP KIF26A GFI1 FCGBP LRRC26 ELAPOR1	9.42e-06	183	118	6	c52b84034503d931f7b87312d2ff86daff14152d
ToppCell	(2)_Fibroblasts-(20)_Fibro-1\|(2)_Fibroblasts / Cell class and subclass of bone marrow stroma cells in homeostatis	COL4A5 SVEP1 SNED1 PRDM8 IGFBP4 CSMD1	1.03e-05	186	118	6	e93415b59dd89bc8a966dab0e0b65fe215933598
ToppCell	SMG-Goblet\|World / shred by cell class for bronchial biopsy	MUC19 HOXB2 FCGBP LRRC26 SEC16A ELAPOR1	1.07e-05	187	118	6	5178118bdec91495253c88f58fd908cf831de7ef
ToppCell	droplet-Kidney-nan-21m-Endothelial-kidney_cortex_artery_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF26A ADAM15 OBSCN SOX13 JAG2 MN1	1.13e-05	189	118	6	2ce330d8078833c05775c481e73770f9ee4a5c88
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PCDHGB6 ADAM15 HEPH IGFBP4 PROB1 MN1	1.13e-05	189	118	6	e60a3d6aa84788c29f23439f1c747431ea581bc3
ToppCell	droplet-Kidney-nan-21m-Endothelial-Pecam____Kidney_cortex_artery_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF26A ADAM15 OBSCN SOX13 JAG2 MN1	1.13e-05	189	118	6	473c87036e04a058b4a5138438b7ba7e1e766799
ToppCell	10x5'v1-week_17-19-Endothelial-stroma-proliferating_EC\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	COL4A5 KIF26A JAG2 SNED1 IGFBP4 AGRN	1.20e-05	191	118	6	dc9e5eb6aa31b8d79aeec33e59b9138dfb469a3b
ToppCell	LA-14._Fibroblast_III\|World / Chamber and Cluster_Paper	RELB KDM6B SVEP1 SNED1 NCOR2 IGFBP4	1.31e-05	194	118	6	803fa83ceada17c38ca9f933b888f7e7b0b90761
ToppCell	cellseq2-Epithelial-Epithelial_Glandular-Mucous-Mucous\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	RAP1GAP PPDPF HOXB2 FCGBP SEC16A ELAPOR1	1.39e-05	196	118	6	357a5440aeebf69688bfe9fbc8585950ad00906b
ToppCell	cellseq2-Epithelial-Epithelial_Glandular-Mucous\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	RAP1GAP PPDPF HOXB2 FCGBP SEC16A ELAPOR1	1.39e-05	196	118	6	98e3f9c886063def16c74ab75fc81511a7872f1c
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_basal-Suprabasal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	LINC01600 TMEM8B POU2AF1 ME3 ELAPOR1 STRA6	1.47e-05	198	118	6	28ada093cec552262731194a04a4b9ff93186c3b
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Perivascular_fibroblast\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NID2 SIK1 SVEP1 SNED1 IGFBP4 STRA6	1.52e-05	199	118	6	dfc5c7a4a093baa7158dd8d4d29a870d9c469a3f
ToppCell	Bronchial-10x5prime-Epithelial-Epi_submucosal-gland-SMG_Mucous\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	NPTX2 RAP1GAP FCGBP LRRC26 ELAPOR1 RNF128	1.52e-05	199	118	6	eb2d1b7e875c5bf833e7a80b43282e12893c34e9
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Perivascular_fibroblast-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NID2 SIK1 SVEP1 SNED1 IGFBP4 STRA6	1.52e-05	199	118	6	c1760581c34b81d1d92c67500a1c8944e9cc6dad
ToppCell	Bronchus_Control_(B.)-Epithelial-TX-Club\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	RAP1GAP ME3 FCGBP LRRC26 ELAPOR1 STRA6	1.56e-05	200	118	6	292c63693eb7f435335a8cfba07aa35b72139393
ToppCell	Parenchymal-10x5prime-Stromal-Peri/Epineurial_-NAF_endoneurial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	OBSCN SNED1 PRDM8 FAM117A TSPAN10 MDC1	1.56e-05	200	118	6	8a4c210a3130f7baedf15ecbc0f4903b97da0352
ToppCell	Frontal_cortex-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cspg5_(Cspg5)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	GSX1 MUC19 FCGBP SLC23A1	3.61e-05	70	118	4	986c7a1002a4ffd3a246495bedde2997ffdc2c9d
ToppCell	Frontal_cortex-Macroglia-POLYDENDROCYTE-P3-Tnr\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	GSX1 MUC19 FCGBP SLC23A1	3.61e-05	70	118	4	c0330216305491d7d57cdbea0ae3cb8e9092c8e3
ToppCell	Frontal_cortex-Macroglia-POLYDENDROCYTE-P3\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	GSX1 MUC19 FCGBP SLC23A1	3.61e-05	70	118	4	86dde790fcdaec2095e2256463953077811145d2
ToppCell	Frontal_cortex-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cspg5_(Cspg5)-\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	GSX1 MUC19 FCGBP SLC23A1	3.61e-05	70	118	4	e604660b2efbc03e21806dcaecf7a72321673ae2
ToppCell	PBMC-Severe-Lymphocyte-B-B_cell-B_naive-B_naive-13\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DDN POU2AF1 KDM6B PROB1 SLC23A3	4.10e-05	144	118	5	b2a9f3b5dd46d27689467f4a5fd717cd5827821f
ToppCell	Globus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Ngfr\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	ESPNL OAS3 CHAT PLA2G4B	6.71e-05	82	118	4	cefd8c6f60ef27fb8823faddca1cf8bbd636f474
ToppCell	Globus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Ngfr-Inhibitory_Neuron.Chat-Gad1Gad2-Slc17a8.Ngfr_(Globus_Pallidus/Nucleus_Basalis_(GP/NB),_cholinergic)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	ESPNL OAS3 CHAT PLA2G4B	6.71e-05	82	118	4	1ed7d7f70f00d6e280cd59c54e710bb724c8b50b
ToppCell	Globus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Ngfr-Inhibitory_Neuron.Chat-Gad1Gad2-Slc17a8.Ngfr_(Globus_Pallidus/Nucleus_Basalis_(GP/NB),_cholinergic)-\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	ESPNL OAS3 CHAT PLA2G4B	6.71e-05	82	118	4	a5d3c5b7012d8ca7418670242d22aad3ed8c5191
ToppCell	facs-Thymus-Epithelium-3m-Epithelial-epithelial_cell_of_thymus\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GRIN2C FCGBP FAM229A LRRC26 RNF128	7.17e-05	162	118	5	3dc39db0d5f6f3d7bcc312a6bce7aaeb914138d1
ToppCell	facs-Thymus-Epithelium-3m-Epithelial\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GRIN2C FCGBP FAM229A LRRC26 RNF128	7.17e-05	162	118	5	0a7138266054ea5954649c8b61ef93905d56b068
ToppCell	facs-Thymus-Epithelium-3m-Epithelial-TECs\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GRIN2C FCGBP FAM229A LRRC26 RNF128	7.17e-05	162	118	5	25323785dd33337bcefd05958a4a1a208a9ceb04
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCDHGB6 FCGBP ELAPOR1 CSMD1 BRSK1	8.75e-05	169	118	5	30141f76e9bfc2b4586429857c72dbc85ba65cc9
ToppCell	NS-critical-d_0-4-Lymphoid-B_cell\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	TAF1C POU2AF1 SIK1 KRBA1 MDC1	9.25e-05	171	118	5	bd1ebd9037a740ad8c01c460d778b0973d8b56df
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1_VIP_PCDH20\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SOX1 HAP1 DNER RIMBP3 RIMBP3B	9.51e-05	172	118	5	35e961c88bfe79046533396912cedf00ca81db7b
ToppCell	facs-Large_Intestine-Distal-24m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HAP1 DISC1 CHAT MN1 PIK3R5	9.77e-05	173	118	5	f0eb48c1283bdde313bb75f6ffc0d2626922d24b
ToppCell	ASK428-Immune-B_cell\|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq	WHRN POU2AF1 IGHG1 PAXIP1 CSMD1	1.00e-04	174	118	5	b5a7a612a515736cf3489afd0f6ad2054d54526f
ToppCell	Adult-Epithelial-basal_cell-D231\|Adult / Lineage, Cell type, age group and donor	COL4A5 HAP1 JAG2 ELAPOR1 PROB1	1.00e-04	174	118	5	a4f98afe7d1cc2617f6f7bc8092c41df57474b30
ToppCell	droplet-Lung-1m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RAP1GAP HAP1 DISC1 RELB ZNF513	1.03e-04	175	118	5	1b910c08d2bfbcc77431ee66103e63a11a9d39fe
ToppCell	356C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	NPTX2 FCGBP LRRC26 ELAPOR1 SMO	1.03e-04	175	118	5	af9c5104c86231cfdb93a0f7d7032379efaa009e
ToppCell	5'-GW_trimst-2-SmallIntestine-Epithelial-mature_enterocytic-Paneth\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RAP1GAP GFI1 FCGBP LRRC26 ELAPOR1	1.03e-04	175	118	5	bffa623511ceb0b9bf76d87f9a10cfadfe0e940f
ToppCell	356C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)\|356C / Donor, Lineage, Cell class and subclass (all cells)	NPTX2 FCGBP LRRC26 ELAPOR1 SMO	1.03e-04	175	118	5	4bfae78ac3a2cb9404382aae96d291504a9cfa14
ToppCell	ASK428-Immune-B_cell\|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq	WHRN POU2AF1 IGHG1 PAXIP1 CSMD1	1.03e-04	175	118	5	e0979e5795a49b4e5c9b88e7fe6b7bda7a413a6c
ToppCell	droplet-Liver-LIVER_NPC-30m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDS1 FCGBP PLEKHM2 LRRC26 CSMD1	1.03e-04	175	118	5	f7cd2ef79d91d64976fcdb5f1e7343b24ba27456
ToppCell	mild_COVID-19_(asymptomatic)-B_memory\|World / disease group, cell group and cell class (v2)	MUC19 POU2AF1 RELB SNED1 IGHG1	1.09e-04	177	118	5	057871e211c6508b2a679d391f3cf0ac7ccfc628
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L6_LAMP5_C1QL2\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SOX13 RIMBP3 RIMBP3C RIMBP3B MN1	1.12e-04	178	118	5	39889db130216655a34796e7030ffeb372465500
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_INF-A\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FRAT1 OAS3 LIMK1 FCGBP PIK3R5	1.15e-04	179	118	5	06d412fc096d88de168969466ce422f0ab5553b2
ToppCell	368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3\|368C / Donor, Lineage, Cell class and subclass (all cells)	TCAF2 PARG LARS2 GFI1 EBF4	1.15e-04	179	118	5	10c7d371937d9d93c12c8d3465430ef9e0c2ec81
ToppCell	mild_COVID-19_(asymptomatic)-cDC\|World / disease group, cell group and cell class (v2)	CDS1 TMEM8B DISC1 OAS3 STRA6	1.18e-04	180	118	5	68d1c867734fb2977b01ac686b20bf602f9a6b72
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-collecting_duct_principal_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCAF2 KIF26A HAP1 STRA6 BRSK1	1.21e-04	181	118	5	7af469f5bcb9b1ab3f35b2758bf2afb87e8eba57
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.3.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GJB4 OAS3 STRA6 NOS2 EBF4	1.27e-04	183	118	5	2dde2fb48e7d31271c2f6b1dd74b2ab0b2cb520c
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-large_intestine_goblet_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RAP1GAP FAM117A FCGBP LRRC26 ELAPOR1	1.27e-04	183	118	5	5a936fb07074cec753bf19e3e3e52499605ea22c
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-Goblet_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RAP1GAP FAM117A FCGBP LRRC26 ELAPOR1	1.27e-04	183	118	5	07c18ccc45ddc9c22e482bd9ffb87f46ebcfe473
ToppCell	facs-Trachea-18m-Epithelial-airway_epithelial-respiratory_basal_cell-basal_epithelial_cell_of_trachea\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GJB4 LARS2 FCGBP LRRC26 ELAPOR1	1.30e-04	184	118	5	45ff845ceed5960a997545c1009012b65e377d50
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_Invariant-Inducer-like-ILC3\|lymph-node_spleen / Manually curated celltypes from each tissue	NPTX2 DNER IGFBP4 ELAPOR1 MN1	1.30e-04	184	118	5	479e60f76c191253e23699c9dd7ef7efc08c59ad
ToppCell	PCW_10-12-Immune_Lymphocytic-Immune_Lymphocytic_NK/ILC-im_ILC2_(21)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	RASGRP4 GFI1 PRDM8 CREB3L3 PIK3R5	1.30e-04	184	118	5	33db879e629821fb75684e60f8f0749cf9623bdd
ToppCell	facs-Trachea-18m-Epithelial-airway_epithelial-respiratory_basal_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GJB4 LARS2 FCGBP LRRC26 ELAPOR1	1.30e-04	184	118	5	2cc2646dee3c6001f7c10b7449c17d1935021958
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PPDPF FCGBP LRRC26 ELAPOR1 STRA6	1.34e-04	185	118	5	5dee5645240637e135677732a35fd416b37367d4
ToppCell	droplet-Lung-nan-18m-Mesenchymal-pulmonary_interstitial_fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCDHGB6 HOXB2 LPP CSMD1 MN1	1.37e-04	186	118	5	b58db5abdd3e9f0214b198c3cbd09b0b3c321eab
ToppCell	droplet-Lung-nan-18m-Mesenchymal-Myofibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCDHGB6 HOXB2 LPP CSMD1 MN1	1.37e-04	186	118	5	cd6502bbf9dce318fdbb4965d49df8951e5f795c
ToppCell	droplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l30\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NID2 RAP1GAP ME3 CSMD1 BRSK1	1.41e-04	187	118	5	8e8b147258982b359447add5027318f5b6d51963
ToppCell	wk_15-18-Endothelial-Blood_vessel_endothelial-GRIA2+_arterial_endo\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	ADAM15 MUC19 SOX13 JAG2 IGFBP4	1.44e-04	188	118	5	366a2d59b9c81d8a7659749f9c07efa46b49a39a
ToppCell	droplet-Kidney-nan-3m-Epithelial-Pecam____Kidney_cortex_artery_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF26A SOX13 JAG2 BRSK1 MN1	1.44e-04	188	118	5	ec0e241de2c8310b4417b9d4e2420d7a1662f1c0
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Macroglial-oligodendrocyte_precursor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GSX1 RAP1GAP RIMBP3 CSMD1 RNF128	1.44e-04	188	118	5	a244fcd092d5bd544e503366b1439b0fbc1ee00e
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Macroglial-Oligodendrocyte_progenitor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GSX1 RAP1GAP RIMBP3 CSMD1 RNF128	1.44e-04	188	118	5	c8530c9ff98666c64a94683261af4288cb790a7e
ToppCell	3'-Broncho-tracheal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_mucus_secreting_cell-SMG_mucous\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PPDPF HOXB2 FCGBP LRRC26 ELAPOR1	1.48e-04	189	118	5	8777a341dd4f02ac5ee45c6c489ce74f4c87ce15
ToppCell	RA-14._Fibroblast_III\|RA / Chamber and Cluster_Paper	RELB KDM6B SNED1 NCOR2 IGFBP4	1.48e-04	189	118	5	46e9a58aacd79db5a02898a8c7244e1884adcfd1
ToppCell	3'-Broncho-tracheal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_mucus_secreting_cell-SMG_mucous-SMG_mucous_L.0.6.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PPDPF HOXB2 FCGBP LRRC26 ELAPOR1	1.48e-04	189	118	5	86d751cca35c42067157e218567daf9ab9d5f907
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KIF26A ADAM15 SOX13 JAG2 MN1	1.48e-04	189	118	5	12b6f1c3bf526b90e112374bf937701f645c5780
ToppCell	3'-Broncho-tracheal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_mucus_secreting_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PPDPF HOXB2 FCGBP LRRC26 ELAPOR1	1.48e-04	189	118	5	ccc5436ef22016559bfdaca12b9ab5ce8d5944b1
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-Epcam____podocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GJB4 FCGBP LRRC26 STRA6 AGRN	1.48e-04	189	118	5	319e42f6e2322208de78bc666fb2c074707eb4da
ToppCell	Adult-Mesenchymal-matrix_fibroblast_2_cell-D175\|Adult / Lineage, Cell type, age group and donor	NID2 SVEP1 SNED1 IGFBP4 MN1	1.52e-04	190	118	5	7dcca3469f3a3b70db0420cb94f7765f39492f06
ToppCell	droplet-Kidney-KIDNEY-30m-Endothelial-Pecam____Kidney_cortex_artery_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF26A ADAM15 SOX13 JAG2 MN1	1.52e-04	190	118	5	cb8798839c27f307955fcc94a1ee40bca95b8e99
ToppCell	droplet-Kidney-KIDNEY-30m-Endothelial-kidney_cortex_artery_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF26A ADAM15 SOX13 JAG2 MN1	1.52e-04	190	118	5	5bf3d0beee69879c95265d07fba023626a7cc808
ToppCell	ILEUM\|World / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	POU2AF1 KDM6B CSRNP1 IGHG1 SOCS1	1.52e-04	190	118	5	4395dbd18c14d491f5066a2ddac438a16b1fd7c3
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	NID2 DNER IGFBP4 MN1 ADAMTSL4	1.52e-04	190	118	5	4f775ee24b14733f06ae40b45f2dc1a0f0df0705
ToppCell	droplet-Skin-nan-21m-Epithelial-basal_cell_of_epidermis\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF703 SIVA1 JAG2 FCGBP AGRN	1.52e-04	190	118	5	c1bfc1960a3df49c0f459454a7363804c32418ee
ToppCell	5'-Adult-LargeIntestine-Epithelial-Tuft-related-Tuft\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NPTX2 HAP1 CHAT ELAPOR1 CSMD1	1.55e-04	191	118	5	54f07e4de61735051498846afb44b1798bed8144
ToppCell	droplet-Lung-1m-Endothelial-venous_endothelial\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KIF26A ADAM15 OBSCN ME3 LRRC26	1.59e-04	192	118	5	1990dc8a81594018a5bf596be99d0b5f0af0f58f
ToppCell	Enterocyte_Progenitors-C_06\|Enterocyte_Progenitors / shred on cell type and cluster	COL4A5 FCGBP IGHG1 NOS2 AGRN	1.59e-04	192	118	5	b9938e1a929c00628cc6ebfdf10cf285167f445c
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_Invariant-Inducer-like-ILC3\|lymph-node_spleen / Manually curated celltypes from each tissue	SEMA6C NPTX2 DNER IGFBP4 ELAPOR1	1.59e-04	192	118	5	e16035b3328f9b1b2e28d234c62ba88387540550
ToppCell	(7)_Epithelial_cells-(7)_Epithelial-G_(Club-Clara_cells)\|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)	PRDM8 FCGBP LRRC26 ELAPOR1 STRA6	1.59e-04	192	118	5	c7c232545fad8ad327ab94bd0def8dc5daacd03d
ToppCell	droplet-Lung-1m-Endothelial-venous_endothelial-vein_endothelial_cell-vein_endothelial_cell\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KIF26A ADAM15 OBSCN ME3 LRRC26	1.59e-04	192	118	5	845cc9c18b4436b07dd3ce7980052683937546d2
ToppCell	droplet-Lung-1m-Endothelial-venous_endothelial-vein_endothelial_cell\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KIF26A ADAM15 OBSCN ME3 LRRC26	1.59e-04	192	118	5	c72a082c93a8825adbfef37f889ba3a7052f201b
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-large_intestine_goblet_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RAP1GAP FAM117A FCGBP SEC16A ELAPOR1	1.63e-04	193	118	5	6a9bce5064938b5b84ad57b4fd4a7841afe100c8
ToppCell	facs-Skin-Anagen-3m-Epithelial-bulge_keratinocyte\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GJB4 DLGAP4 LARS2 MN1 ADAMTSL4	1.63e-04	193	118	5	eba3c70701b051bc1ed1f4db9270cb27a77ffc3e
ToppCell	facs-Large_Intestine-Distal-24m-Epithelial-Reg4/cKit+_deep_crypt_secretory_cells_(Distal)\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RAP1GAP GFI1 FCGBP LRRC26 ELAPOR1	1.63e-04	193	118	5	5a92697430f16c49e19a5f727d289d7bd1ece31c
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	DNER SVEP1 IGFBP4 MN1 ADAMTSL4	1.63e-04	193	118	5	adc9fc94f9ec686a417d08c0b8b7b7ab687afec0
ToppCell	LA-14._Fibroblast_III\|LA / Chamber and Cluster_Paper	RELB KDM6B SNED1 NCOR2 IGFBP4	1.63e-04	193	118	5	7426c291bac59e539c427bcaae18abc7d397d44e
ToppCell	facs-Large_Intestine-Distal-24m-Epithelial-secretory_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RAP1GAP GFI1 FCGBP LRRC26 ELAPOR1	1.63e-04	193	118	5	64bcdbb422f8da6fc3275e82f6aaf562f546a180
ToppCell	facs-Large_Intestine-Distal-18m-Epithelial-Reg4/cKit+_deep_crypt_secretory_cells_(Distal)\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RAP1GAP KIF26A GFI1 LRRC26 ELAPOR1	1.67e-04	194	118	5	0797245ebfa389a6f66874cb0f11297f1456e600
ToppCell	facs-Skin-Anagen-3m-Epithelial-outer_bulge\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GJB4 DLGAP4 LARS2 MN1 ADAMTSL4	1.67e-04	194	118	5	5d30d3d41d5f19cdf3077cc609aa2738762cb8c5
ToppCell	facs-Large_Intestine-Distal-18m-Epithelial-secretory_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RAP1GAP KIF26A GFI1 LRRC26 ELAPOR1	1.67e-04	194	118	5	0241b4b88d6210b4c1b8aa99db17115b18142f01
Drug	Oxamniquine [21738-42-1]; Up 200; 14.4uM; MCF7; HT_HG-U133A	WHRN DLGAP4 OAS3 GFI1 SVEP1 SNED1 NCOR2 ACBD4 DYRK1B AGRN PIK3R5	3.73e-09	195	113	11	4124_UP
Drug	Muramic acid, N-acetyl [10597-89-4]; Up 200; 13.6uM; MCF7; HT_HG-U133A	WHRN SPHK2 TAF1C BCORL1 LARS2 SOX13 KLHL22 AGRN ELL	5.24e-07	193	113	9	3262_UP
Drug	Gelsemine [509-15-9]; Down 200; 12.4uM; MCF7; HT_HG-U133A	COL4A5 BCORL1 KDM6B LARS2 SOX13 GFI1 KLHL22 FGD1 AGRN	6.49e-07	198	113	9	2817_DN
Drug	Theophylline monohydrate [5967-84-0]; Up 200; 20.2uM; MCF7; HT_HG-U133A	BCORL1 ARID1A SVEP1 NCOR2 ACBD4 ELAPOR1 SMO ELL	6.66e-06	198	113	8	3326_UP
Drug	Progesterone [57-83-0]; Up 200; 12.8uM; MCF7; HT_HG-U133A	SPHK2 NPTX2 GFI1 SVEP1 NCOR2 LIMK1 ULK1 KIF13A	6.91e-06	199	113	8	3287_UP
Drug	Rifabutin [72559-06-9]; Down 200; 4.8uM; MCF7; HT_HG-U133A	PPDPF OAS3 KDM6B ARID1A KLHL22 ZNF512B IGFBP4	3.77e-05	184	113	7	4349_DN
Drug	LY 294002; Up 200; 10uM; MCF7; HT_HG-U133A	NUDT18 SIVA1 SIK1 RELB ACBD4 DYRK1B AGRN	4.62e-05	190	113	7	6998_UP
Drug	Metixene hydrochloride [1553-34-0]; Up 200; 11.6uM; MCF7; HT_HG-U133A	WHRN SPHK2 BCORL1 RELB SVEP1 KLHL22 NCOR2	4.94e-05	192	113	7	3313_UP
Drug	17-AAG; Down 200; 1uM; MCF7; HG-U133A	RAP1GAP HAP1 ADAM15 TAF1C DLGAP4 RELB ADAMTSL4	5.28e-05	194	113	7	428_DN
Drug	Tetrandrine [518-34-3]; Down 200; 6.4uM; MCF7; HT_HG-U133A	OAS3 SOX13 KLHL22 ZNF512B JAG2 LIMK1 PLEKHM2	5.45e-05	195	113	7	6082_DN
Drug	Pyridoxine hydrochloride [58-56-0]; Up 200; 19.4uM; PC3; HT_HG-U133A	NID2 TAF1C ARID1A SOX13 ZNF335 ADAMTSL4 PIK3R5	5.45e-05	195	113	7	5813_UP
Drug	Cyclopenthiazide [742-20-1]; Up 200; 10.6uM; MCF7; HT_HG-U133A	RELB SOX13 SVEP1 KLHL22 HOXB2 PLEKHM2 FGD1	5.45e-05	195	113	7	4813_UP
Drug	3-alpha-Hydroxy-5-beta-androstan-17-one [53-42-9]; Down 200; 13.8uM; PC3; HT_HG-U133A	NID2 SPHK2 DDN HOXB2 NCOR2 LPP ELL	5.63e-05	196	113	7	3742_DN
Drug	Sulfadoxine [2447-57-6]; Up 200; 12.8uM; MCF7; HT_HG-U133A	NUDT18 TAF1C GFI1 KLHL22 NCOR2 LIMK1 ELL	5.63e-05	196	113	7	7205_UP
Drug	Etidronic acid, disodium salt [7414-83-7]; Up 200; 16uM; PC3; HT_HG-U133A	SPHK2 DDN SVEP1 KLHL22 NCOR2 DYRK1B KIF13A	5.63e-05	196	113	7	4564_UP
Drug	Gossypol [303-45-7]; Down 200; 7.8uM; PC3; HT_HG-U133A	WHRN NID2 DISC1 SOX13 SVEP1 ACBD4 AGRN	5.63e-05	196	113	7	4296_DN
Drug	Repaglinide [135062-02-1]; Up 200; 8.8uM; MCF7; HT_HG-U133A	WHRN TMEM8B TAF1C RELB KLHL22 SOCS1 KIF13A	5.63e-05	196	113	7	3558_UP
Drug	Buflomedil hydrochloride [35543-24-9]; Down 200; 11.6uM; MCF7; HT_HG-U133A	NUDT18 WHRN COL4A5 SPHK2 DISC1 KLHL22 LPP	5.63e-05	196	113	7	4840_DN
Drug	Pivmecillinam hydrochloride [32887-03-9]; Up 200; 8.4uM; MCF7; HT_HG-U133A	NUDT18 HAP1 TMEM8B OAS3 GFI1 KLHL22 STRA6	5.63e-05	196	113	7	3535_UP
Drug	Methamphetamine	NPTX2 ADAM15 TAF1C OBSCN SIK1 CHAT ICE1 KDM6B ARID1A KLHL22 NCOR2 FCGBP PLEKHM2 STRA6 CSMD1 MN1 NOS2 AGRN PIK3R5	5.76e-05	1401	113	19	ctd:D008694
Drug	Sulindac [38194-50-2]; Up 200; 11.2uM; MCF7; HT_HG-U133A	NUDT18 WHRN TMEM8B RELB STRA6 KIF13A ADAMTSL4	5.81e-05	197	113	7	5528_UP
Drug	Delsoline [509-18-2]; Down 200; 8.6uM; HL60; HT_HG-U133A	ADAM15 DLGAP4 KDM6B ME3 KLHL22 JAG2 IGFBP4	5.81e-05	197	113	7	2513_DN
Drug	N6-methyladenosine [1867-73-8]; Down 200; 14.2uM; PC3; HT_HG-U133A	WHRN DDN KDM6B ME3 KLHL22 NCOR2 MN1	5.81e-05	197	113	7	6732_DN
Drug	Praziquantel [55268-74-1]; Up 200; 12.8uM; MCF7; HT_HG-U133A	HAP1 DISC1 KLHL22 LIMK1 LPP PIK3R5 ELL	5.81e-05	197	113	7	7228_UP
Drug	Cephalosporanic acid, 7-amino [957-68-6]; Up 200; 14.6uM; MCF7; HT_HG-U133A	WHRN SPHK2 TAF1C KDM6B SOX13 KLHL22 ACBD4	6.00e-05	198	113	7	3258_UP
Drug	(+,-)-Octopamine hydrochloride [770-05-8]; Up 200; 21uM; PC3; HT_HG-U133A	WHRN NPTX2 HAP1 TAF1C KLHL22 ACBD4 SMO	6.20e-05	199	113	7	5050_UP
Drug	Rilmenidine hemifumarate [54187-04-1]; Up 200; 8.4uM; HL60; HT_HG-U133A	NUDT18 HAP1 SOX13 ME3 FGD1 STRA6 ELL	6.20e-05	199	113	7	3133_UP
Drug	CP-690334-01 [459212-38-5]; Down 200; 1uM; MCF7; HT_HG-U133A	HAP1 GFI1 SVEP1 LPP ELAPOR1 FGD1 KIF13A	6.20e-05	199	113	7	4383_DN
Drug	Levopropoxyphene napsylate [5714-90-9]; Down 200; 7.4uM; MCF7; HT_HG-U133A	WHRN DISC1 TAF1C BCORL1 KLHL22 KIF13A ELL	6.20e-05	199	113	7	3543_DN
Drug	Epirizole [18694-40-1]; Up 200; 17uM; MCF7; HT_HG-U133A	HAP1 OAS3 SVEP1 NCOR2 ACBD4 KIF13A ELL	6.20e-05	199	113	7	5995_UP
Drug	Thiamphenicol [15318-45-3]; Up 200; 11.2uM; MCF7; HT_HG-U133A	SPHK2 TMEM8B TAF1C LPP STRA6 KIF13A ELL	6.39e-05	200	113	7	1704_UP
Disease	glycerate measurement	AGRN SLC23A1 SLC23A3	2.34e-05	15	112	3	EFO_0021029
Disease	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 measurement	ADAM15 SVEP1	8.53e-05	4	112	2	EFO_0803113
Disease	marginal zone B- and B1-cell-specific protein measurement	IGHG1 PROB1	8.53e-05	4	112	2	EFO_0802730
Disease	tartronate (hydroxymalonate) measurement	SLC23A1 SLC23A3	8.53e-05	4	112	2	EFO_0800944
Disease	melancholic depression (implicated_via_orthology)	HAP1 DISC1	8.53e-05	4	112	2	DOID:1595 (implicated_via_orthology)
Disease	Endometrial Stromal Sarcoma	NUTM2A NUTM2B	1.42e-04	5	112	2	C0206630
Disease	Clear cell sarcoma of kidney	NUTM2E NUTM2B	2.12e-04	6	112	2	C0334488
Disease	Hodgkins lymphoma	POU2AF1 CHAT FCGBP LPP	2.74e-04	82	112	4	EFO_0000183
Disease	response to 4'-epidoxorubicin, response to antineoplastic agent	GSX1 ICE1	5.05e-04	9	112	2	GO_0097327, GO_1902522
Disease	pancreatic cancer (is_marker_for)	RAP1GAP ADAM15 SMO NOS2	6.05e-04	101	112	4	DOID:1793 (is_marker_for)
Disease	threonate measurement	SLC23A1 SLC23A3	6.30e-04	10	112	2	EFO_0021032
Disease	retinal drusen	PRR18 SVEP1 SLC23A1	9.71e-04	51	112	3	EFO_1001155
Disease	chronic lymphocytic leukemia	HAP1 OAS3 CSRNP1 LPP	1.12e-03	119	112	4	EFO_0000095
Disease	Metastatic melanoma	SIK1 DYRK1B BRSK1	1.15e-03	54	112	3	C0278883
Disease	ascorbic acid 3-sulfate measurement	SLC23A1 SLC23A3	1.26e-03	14	112	2	EFO_0800173
Disease	Acute Myeloid Leukemia, M1	GFI1 LPP MN1 AGRN	1.34e-03	125	112	4	C0026998
Disease	Acute Myeloid Leukemia (AML-M2)	GFI1 LPP MN1 AGRN	1.34e-03	125	112	4	C1879321
Disease	creatinine measurement	PPDPF OBSCN POU2AF1 ARID1A PHC2 JAG2 PRDM8 LPP RNF128 SLC23A1 ELL	1.43e-03	995	112	11	EFO_0004518
Disease	Cardiovascular Abnormalities	STRA6 NOS2	1.65e-03	16	112	2	C0243050
Disease	vitamin C measurement	SLC23A1 SLC23A3	1.65e-03	16	112	2	EFO_0600003
Disease	myelodysplastic syndrome (is_marker_for)	RAP1GAP GFI1	2.59e-03	20	112	2	DOID:0050908 (is_marker_for)
Disease	Malignant neoplasm of breast	NID2 CDS1 RAP1GAP PCDHGB6 BCORL1 OBSCN ARID1A JAG2 ELAPOR1 NOS2 NLRP8	2.60e-03	1074	112	11	C0006142
Disease	sensory peripheral neuropathy, remission	PRR18 CSMD1	3.43e-03	23	112	2	EFO_0009785, MONDO_0002321
Disease	cancer (implicated_via_orthology)	CDS1 ARID1A PHC2 TSPAN10 PIPSL	3.63e-03	268	112	5	DOID:162 (implicated_via_orthology)
Disease	Intrahepatic Cholangiocarcinoma	ARID1A NOS2	3.73e-03	24	112	2	C0345905
Disease	Extrahepatic Cholangiocarcinoma	ARID1A NOS2	3.73e-03	24	112	2	C3805278

Protein segments in the cluster

Peptide	Gene	Start	Entry
TPGPGHATETCPAPP	FAM229A	6	H3BQW9
HATETCPAPPGPERS	FAM229A	11	H3BQW9
GGETPEFPGCHSPAP	DCANP1	31	Q8TF63
SSPHLCPEPGGSSGP	C1orf167	321	Q5SNV9
PDCAPATHATPGAPA	ELL	471	P55199
HRGSCPGPREAVSPP	CDS1	6	Q92903
AAGARPPASPEPCHG	ADAMTSL4	706	Q6UY14
PVCVPITCGHPGNPA	CSMD1	2731	Q96PZ7
PATSPAGCHPAQPGK	CREB3L3	106	Q68CJ9
HLEESVIPGTAPCPP	ACBD4	196	Q8NC06
LDHDLPGNSCPCPGP	ADAM15	356	Q13444
PDGHRAPAPPQSGSC	FAM117A	241	Q9C073
PRCEHPPPGPVCGSD	AGRN	621	O00468
APICPPAPGSASVPH	BCORL1	201	Q5H9F3
VGTNPSVPAPSPHCG	LINC01600	66	Q96MT4
APAGSATAAPCAPHP	DDN	346	O94850
CGPEVPPTPPGSHSA	DISC1	191	Q9NRI5
PAPPATCPSLGVGTD	DLGAP4	271	Q9Y2H0
VSLVGGPADCSPPHP	DYRK1B	566	Q9Y463
QPCEVLTPSPPGLGH	RIMBP3B	356	A6NNM3
QPCEVLTPSPPGLGH	RIMBP3C	356	A6NJZ7
PPAPPHASAVVCSGG	RELB	506	Q01201
SSTECPGEAIPHPPG	PPDPF	31	Q9H3Y8
CSVSPGALIPPHGGE	PCDHGB6	781	Q9Y5F9
GVGAPPHSAAAALPP	ARID1A	131	O14497
EDPSHPCILIGPGTG	NOS2	971	P35228
PVAFPPGGKPCSQHI	PAXIP1	696	Q6ZW49
GADNPEHSPPCSVSP	CYREN	86	Q9BWK5
PAATFPPATHCPLGG	NCOR2	1906	Q9Y618
PPATHCPLGGTLDGV	NCOR2	1911	Q9Y618
LPHAAVPCSGPEPTA	ESPNL	951	Q6ZVH7
PDAPPAEPPGLHCSS	KRBA1	916	A5PL33
GPCLSPPRAIPGDQH	MDC1	776	Q14676
LGLFCEPAPEPGHPA	GFI1	151	Q99684
VHSCDSAPAGEPPAP	NUDT18	21	Q6ZVK8
IPLLHKCDPPSPGSG	NLRP8	591	Q86W28
SEAPDCPTHPGLPGP	CSRNP1	366	Q96S65
AEEPPSTPCLPRSGH	JAG2	951	Q9Y219
PASGVKTHCPPCNPG	ELAPOR1	371	Q6UXG2
PAGAAAPEEPHGLSP	KCNT1	21	Q5JUK3
PPGAESHGCLPATRP	KDM6B	341	O15054
PPAPVCHGPLGEEKS	MUC19	8156	Q7Z5P9
PPSSPACVPGRAGQH	PARG	51	Q86W56
PVPSTPAPHASCGSE	RASGRP4	606	Q8TDF6
CVTASQLHGPPGPPA	GSX1	61	Q9H4S2
SAPCAPPLQPKGGHS	LPP	361	Q93052
GVPPSSPTHGPAPAC	KIF26A	1466	Q9ULI4
DPTCPGAPAVLHFPL	PLA2G4B	686	P0C869
LGPPCTGLHARAPDP	PDPK2P	361	Q6A1A2
GVHLGCPDVLPQTPP	PIPSL	451	A2A3N6
CHPPEVVPGALSADP	HOXB2	246	P14652
SAPQEGCSPHPAVAP	OBSCN	7041	Q5VST9
GCSPHPAVAPCPPGS	OBSCN	7046	Q5VST9
VPGTQTPPGSTPPHC	NID2	991	Q14112
SATPAVGPPLEGPEH	POU2AF1	156	Q16633
PVPGRLPPCASGHAA	ICE1	1726	Q9Y2F5
SVCPLPAGHGEPGIA	KLHL22	526	Q53GT1
PPQACPRAHGEGLPD	EBF4	566	Q9BQW3
ATDGPLAPCHGLVPP	FCGBP	2271	Q9Y6R7
GPGDPAALTCAPSPS	HAP1	16	P54257
GPHIPPSDEICEPGP	COL4A5	441	P29400
PDTCPPYVLSQGGHP	GJB4	231	Q9NTQ9
LGGKHEPDPCLEPAP	BRSK1	286	Q8TDC3
TPTAPAQGCHSKPGP	ME3	26	Q16798
AQHSPASPCGPPGAP	FRAT1	56	Q92837
GLFHPVLGTPCQPPS	C19orf54	261	Q5BKX5
THTCPPCPAPELLGG	IGHG1	106	P01857
EPCSGQVGSEPPCHP	CROCCP3	196	Q8IVE0
GGVCTSRPEPDPQHP	DNER	56	Q8NFT8
RELGSPHPTPCTGPA	SCNN1D	41	P51172
APATCAPPRPAGSGH	PRR18	86	Q8N4B5
CPAPGPTGAASIVPS	OAS3	386	Q9Y6K5
ESLGPTPCHCSPPEG	PLEKHM2	756	Q8IWE5
GLPADCGPHDPSLAP	MN1	651	Q10571
PPQAHNPGCIVPSGS	KIF13A	1496	Q9H1H9
SPPQDHRPTCPGVGT	NUTM2A	716	Q8IVF1
SPPQDHRPTCPGVGT	NUTM2B	716	A6NNL0
SPPQDHRPTCPGVGT	NUTM2E	716	B1AL46
PEPCALAPNPSSEGH	PRR23A	196	A6NEV1
GTPIPIVHCPVCGPT	LARS2	456	Q15031
CPCPGAPVGVHPSLA	TCAF2	86	A6NFQ2
QPCEVLTPSPPGLGH	RIMBP3	356	Q9UFD9
AGPPGDTQPDCHAPT	TAF1C	611	Q15572
GALEPCHPADGVGPT	PRDM8	521	Q9NQV8
SPCVGSPGPHARSPL	PRR23B	236	Q6ZRT6
VPPHAGPTAQDPACL	HEPH	521	Q9BQS7
SDDGPPSHSLCPGPP	FGD1	301	P98174
PPDGPGALNACNPHT	RNF128	86	Q8TEB7
SPHPDAGKLGDPACP	RAP1GAP	631	P47736
IAPCDGPGAAPLPST	SIK1B	686	A0A0B4J2F2
IAPCDGPGAAPLPST	SIK1	686	P57059
GCLLPPSPSGHPDQT	WHRN	701	Q9P202
PGPSLGDEAIHCPPC	IGFBP4	16	P22692
PPAPAHSRAPCPGDL	SOX1	326	O00570
ALPPEAVHAGCPLPA	NPTX2	31	P47972
APEPPGSHPVGTLDA	PROB1	586	E7EW31
PVNCGPPEDLAHGFP	SVEP1	2946	Q4LDE5
PCPAVPAPAPGDTHF	SOCS1	41	O15524
PPPPHACSRGLSLEG	SLC23A3	346	Q6PIS1
PEGEVPSCHTSIPPG	STRA6	36	Q9BX79
PPGFSGRHCEIAPSP	SNED1	646	Q8TER0
PAGNPGCSPHPRAAT	CHAT	51	P28329
RTHAGPPTPPCPTCG	ZNF513	226	Q8N8E2
LHVPPGGASFLPDCG	ZNF513	276	Q8N8E2
KPGGSQQCHPPTPDT	PHC2	416	Q8IXK0
SSCVPRPPSHGGPTR	SOX13	316	Q9UN79
SAACPPFPPHGAPVS	ZNF703	196	Q9H7S9
PVPSGVPCATSVPHF	SEC16A	236	O15027
STCGPPDHLLPPLGT	SPHK2	511	Q9NRA0
VKRSHGTSPGACPPP	PIK3R5	561	Q8WYR1
ACARLAGAPPPPVHA	SLC23A1	341	Q9UHI7
PALLGGPSPRPHECA	SEMA6C	801	Q9H3T2
TPAEGPGTTSPPEHC	TMEM8B	21	A6NDV4
SAAVTGPPPPLSHCG	SMO	51	Q99835
PEPGPRPHCSAAGAI	RBPJ	446	Q06330
SKEAPAPVAHPAPGG	ZNF512B	481	Q96KM6
SVHRPPTSGCLGPVP	TSPAN10	21	Q9H1Z9
VGSGHCPLPTPAQFP	nan	41	Q5VSD8
GPEPPSPAKTHCVGD	ZNF335	971	Q9H4Z2
PVPACAGSSAPGSPA	nan	121	Q8N6K4
PPGVKPPESHVCGEV	ZNF861P	31	O60384
GCAVVHLPESPKPGP	SIVA1	61	O15304
ARHLVPGPCSEAPAP	ULK1	786	O75385
EAPAPELPAPGHGCS	ULK1	796	O75385
PHGCASPADPGSPAA	LRRC26	316	Q2I0M4
SIDPPHGPPGCGTEH	LIMK1	181	P53667
PAPAGDCRVHPGPVS	GRIN2C	311	Q14957