Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionphosphatidylinositol-3,4,5-trisphosphate binding

AKT1 PARD3 ARAP1 ARAP2

7.63e-0549924GO:0005547
GeneOntologyMolecularFunctionSUMO ligase activity

RGPD4 RGPD8 RGPD3

1.02e-0420923GO:0061665
GeneOntologyBiologicalProcessNLS-bearing protein import into nucleus

RGPD4 RGPD8 RGPD3 RGPD5

1.70e-0620924GO:0006607
GeneOntologyBiologicalProcesspeptidyl-amino acid modification

RGPD4 JAK1 SMG1 POGLUT3 NAA15 RGPD8 JMJD6 ENPP2 RGPD3 NSD1 AKT1 AKT2 BRSK1 PARD3 NOS1 IFNAR1

5.97e-069769216GO:0018193
GeneOntologyBiologicalProcessdouble-strand break repair via alternative nonhomologous end joining

LIG3 TOPBP1 POLQ

7.07e-069923GO:0097681
GeneOntologyBiologicalProcesspositive regulation of glucokinase activity

RGPD4 RGPD8 RGPD3

7.07e-069923GO:0033133
GeneOntologyBiologicalProcesspositive regulation of hexokinase activity

RGPD4 RGPD8 RGPD3

1.01e-0510923GO:1903301
GeneOntologyBiologicalProcessretinal cell apoptotic process

THRB GDF6 AKT2

1.01e-0510923GO:1990009
GeneOntologyBiologicalProcessproacrosomal vesicle fusion

SOX30 KIAA0319L

1.97e-052922GO:0120211
GeneOntologyBiologicalProcessregulation of glucokinase activity

RGPD4 RGPD8 RGPD3

2.38e-0513923GO:0033131
GeneOntologyBiologicalProcessregulation of hexokinase activity

RGPD4 RGPD8 RGPD3

3.02e-0514923GO:1903299
GeneOntologyBiologicalProcessregulation of dendrite morphogenesis

NSMF MYO5B SYNE1 EEF2K CHRNA3

9.81e-05103925GO:0048814
GeneOntologyBiologicalProcessnegative regulation of long-chain fatty acid import across plasma membrane

AKT1 AKT2

1.17e-044922GO:0010748
GeneOntologyBiologicalProcessnegative regulation of long-chain fatty acid import into cell

AKT1 AKT2

1.17e-044922GO:0140213
GeneOntologyBiologicalProcessapical constriction

FRMD6 PARD3

1.95e-045922GO:0003383
GeneOntologyBiologicalProcessneurotransmitter receptor transport to plasma membrane

MYLK MYO5B CLSTN1

2.59e-0428923GO:0098877
GeneOntologyBiologicalProcessregulation of carbohydrate biosynthetic process

RGPD4 RGPD8 RGPD3 AKT1 AKT2

3.13e-04132925GO:0043255
GeneOntologyBiologicalProcessregulation of phosphorylation

RGPD4 RGPD8 ENPP2 RGPD3 NSD1 AKT1 EEF2K AKT2 ACVR2A RB1CC1 ADTRP PARD3 NOS1 CHRNA3 IFNAR1

3.27e-0412269215GO:0042325
GeneOntologyBiologicalProcessregulation of glucose metabolic process

RGPD4 RGPD8 RGPD3 AKT1 AKT2

3.36e-04134925GO:0010906
GeneOntologyBiologicalProcessregulation of long-chain fatty acid import across plasma membrane

AKT1 AKT2

4.07e-047922GO:0010746
GeneOntologyBiologicalProcessperipheral nervous system axon ensheathment

AKT1 AKT2 PARD3

4.25e-0433923GO:0032292
GeneOntologyBiologicalProcessmyelination in peripheral nervous system

AKT1 AKT2 PARD3

4.25e-0433923GO:0022011
GeneOntologyBiologicalProcessregulation of nervous system development

MYO5B ENPP2 EIF4G2 LRTM1 AKT1 EEF2K KDM4A PARD3 CLSTN1 NOS1

4.70e-046259210GO:0051960
GeneOntologyBiologicalProcesscentrosome localization

SYNE1 PARD3B PARD3

5.07e-0435923GO:0051642
GeneOntologyBiologicalProcessregulation of phosphate metabolic process

RGPD4 NSMF RGPD8 ENPP2 RGPD3 NSD1 AKT1 EEF2K AKT2 ACVR2A RB1CC1 ADTRP PARD3 NOS1 CHRNA3 IFNAR1

5.09e-0414219216GO:0019220
GeneOntologyBiologicalProcessregulation of phosphorus metabolic process

RGPD4 NSMF RGPD8 ENPP2 RGPD3 NSD1 AKT1 EEF2K AKT2 ACVR2A RB1CC1 ADTRP PARD3 NOS1 CHRNA3 IFNAR1

5.17e-0414239216GO:0051174
GeneOntologyBiologicalProcesspositive regulation of phosphate metabolic process

RGPD4 NSMF RGPD8 ENPP2 RGPD3 AKT1 AKT2 ACVR2A RB1CC1 ADTRP NOS1 CHRNA3

5.25e-048799212GO:0045937
GeneOntologyBiologicalProcesspositive regulation of phosphorus metabolic process

RGPD4 NSMF RGPD8 ENPP2 RGPD3 AKT1 AKT2 ACVR2A RB1CC1 ADTRP NOS1 CHRNA3

5.25e-048799212GO:0010562
GeneOntologyBiologicalProcessmicrotubule organizing center localization

SYNE1 PARD3B PARD3

5.51e-0436923GO:0061842
GeneOntologyBiologicalProcessregulation of dendrite development

NSMF MYO5B SYNE1 EEF2K CHRNA3

5.63e-04150925GO:0050773
GeneOntologyBiologicalProcesspeptidyl-serine modification

SMG1 POGLUT3 NSD1 AKT1 AKT2 BRSK1 NOS1

5.64e-04319927GO:0018209
GeneOntologyBiologicalProcessprotein localization to cell periphery

RAPGEF6 MYLK MYO5B ABCA12 ASB3 AKT1 AKT2 CLSTN1

5.97e-04422928GO:1990778
GeneOntologyBiologicalProcessprotein peptidyl-prolyl isomerization

RGPD4 RGPD8 RGPD3

6.47e-0438923GO:0000413
GeneOntologyBiologicalProcessperipheral nervous system myelin maintenance

AKT1 AKT2

6.94e-049922GO:0032287
GeneOntologyBiologicalProcessregulation of long-chain fatty acid import into cell

AKT1 AKT2

6.94e-049922GO:0140212
GeneOntologyBiologicalProcesspositive regulation of phosphorylation

RGPD4 RGPD8 ENPP2 RGPD3 AKT1 AKT2 ACVR2A RB1CC1 ADTRP NOS1 CHRNA3

6.97e-047809211GO:0042327
GeneOntologyCellularComponentcytoplasmic periphery of the nuclear pore complex

RGPD4 RGPD8 RGPD3

4.55e-068923GO:1990723
GeneOntologyCellularComponentnuclear pore cytoplasmic filaments

RGPD4 RGPD8 RGPD3

9.68e-0610923GO:0044614
GeneOntologyCellularComponentannulate lamellae

RGPD4 RGPD8 RGPD3

2.90e-0514923GO:0005642
GeneOntologyCellularComponentcell cortex

NSMF MYO5B TCHP PARD3B AKT1 AKT2 PLEKHH2 PARD3 EPB42

3.77e-05371929GO:0005938
GeneOntologyCellularComponentnuclear pore nuclear basket

RGPD4 RGPD8 RGPD3

6.42e-0518923GO:0044615
GeneOntologyCellularComponentnuclear inclusion body

RGPD4 RGPD8 RGPD3

8.91e-0520923GO:0042405
GeneOntologyCellularComponentdendritic spine

CACNA1S NSMF MYO5B SYNE1 EEF2K CLSTN1 NOS1

9.70e-05242927GO:0043197
GeneOntologyCellularComponentSUMO ligase complex

RGPD4 RGPD8 RGPD3

1.04e-0421923GO:0106068
GeneOntologyCellularComponentneuron spine

CACNA1S NSMF MYO5B SYNE1 EEF2K CLSTN1 NOS1

1.10e-04247927GO:0044309
GeneOntologyCellularComponentapical cortex

MYO5B TCHP

8.43e-0410922GO:0045179
GeneOntologyCellularComponentnuclear membrane

RGPD4 NSMF RGPD8 SYNE1 RGPD3 RB1CC1 NOS1

8.85e-04349927GO:0031965
GeneOntologyCellularComponentnuclear pore

RGPD4 RGPD8 RGPD3 RGPD5

1.04e-03101924GO:0005643
GeneOntologyCellularComponenttransferase complex

RGPD4 GTF2F2 NAA15 RGPD8 ANAPC1 RGPD3 NSD1 CHD8 ACVR2A RB1CC1 PARD3 KLHL22

1.04e-039639212GO:1990234
MousePhenoelevated level of mitotic sister chromatid exchange

RGPD4 LIG3 RGPD8 RGPD3

1.25e-0616744MP:0003701
DomainGrip

RGPD4 RGPD8 RGPD3 RGPD5

1.85e-0711934SM00755
DomainGRIP

RGPD4 RGPD8 RGPD3 RGPD5

1.85e-0711934PF01465
DomainRan_BP1

RGPD4 RGPD8 RGPD3 RGPD5

2.77e-0712934PF00638
DomainRANBD1

RGPD4 RGPD8 RGPD3 RGPD5

2.77e-0712934PS50196
DomainGRIP_dom

RGPD4 RGPD8 RGPD3 RGPD5

2.77e-0712934IPR000237
DomainGRIP

RGPD4 RGPD8 RGPD3 RGPD5

2.77e-0712934PS50913
DomainRanBD

RGPD4 RGPD8 RGPD3 RGPD5

3.98e-0713934SM00160
DomainRan_bind_dom

RGPD4 RGPD8 RGPD3 RGPD5

3.98e-0713934IPR000156
DomainRab_bind

RGPD4 RGPD8 RGPD3

4.12e-067933PF16704
DomainGCC2_Rab_bind

RGPD4 RGPD8 RGPD3

4.12e-067933IPR032023
DomainPH_dom-like

RGPD4 JAK1 RGPD8 FRMD6 RGPD3 AKT1 AKT2 PLEKHH2 ARAP1 ARAP2 RGPD5

8.69e-064269311IPR011993
Domain-

RGPD4 RGPD8 RGPD3

1.40e-05109331.10.220.60
DomainDUF3534

PARD3B PARD3

2.45e-052932IPR021922
DomainDUF3534

PARD3B PARD3

2.45e-052932PF12053
DomainKinase-like_dom

JAK1 SMG1 MYLK SMARCC1 CHD9 AKT1 EEF2K AKT2 ACVR2A BRSK1 STK31

7.88e-055429311IPR011009
Domain-

RGPD4 RGPD8 FRMD6 RGPD3 AKT1 AKT2 PLEKHH2 ARAP1 ARAP2

1.44e-043919392.30.29.30
DomainBRCT_dom

LIG3 TOPBP1 SMARCC1

3.58e-0428933IPR001357
DomainBRK

CHD9 CHD8

3.63e-046932SM00592
DomainBRK_domain

CHD9 CHD8

3.63e-046932IPR006576
DomainBRK

CHD9 CHD8

3.63e-046932PF07533
DomainChromo/shadow_dom

SMARCC1 CHD9 CHD8

5.85e-0433933IPR000953
DomainCHROMO

SMARCC1 CHD9 CHD8

5.85e-0433933SM00298
DomainPDZ

RAPGEF6 GIPC2 PARD3B PARD3 NOS1

6.97e-04141935PF00595
DomainRA

RAPGEF6 ARAP1 ARAP2

7.58e-0436933PF00788
DomainRA

RAPGEF6 ARAP1 ARAP2

8.21e-0437933PS50200
DomainPDZ

RAPGEF6 GIPC2 PARD3B PARD3 NOS1

8.67e-04148935SM00228
DomainTPR-contain_dom

RGPD4 NAA15 RGPD8 RGPD3 RGPD5

9.21e-04150935IPR013026
Domain-

RAPGEF6 GIPC2 PARD3B PARD3 NOS1

9.21e-041509352.30.42.10
DomainPDZ

RAPGEF6 GIPC2 PARD3B PARD3 NOS1

9.49e-04151935PS50106
DomainPDZ

RAPGEF6 GIPC2 PARD3B PARD3 NOS1

9.77e-04152935IPR001478
DomainRA_dom

RAPGEF6 ARAP1 ARAP2

1.03e-0340933IPR000159
DomainTPR-like_helical_dom

RGPD4 NAA15 RGPD8 RGPD3 EEF2K RGPD5

1.09e-03233936IPR011990
DomainTPR_REGION

RGPD4 NAA15 RGPD8 RGPD3 RGPD5

1.41e-03165935PS50293
DomainTPR

RGPD4 NAA15 RGPD8 RGPD3 RGPD5

1.41e-03165935PS50005
DomainFERM_central

JAK1 FRMD6 PLEKHH2

1.87e-0349933IPR019748
DomainFERM_domain

JAK1 FRMD6 PLEKHH2

1.87e-0349933IPR000299
DomainFERM_1

JAK1 FRMD6 PLEKHH2

1.98e-0350933PS00660
DomainFERM_2

JAK1 FRMD6 PLEKHH2

1.98e-0350933PS00661
DomainFERM_3

JAK1 FRMD6 PLEKHH2

1.98e-0350933PS50057
DomainBand_41_domain

JAK1 FRMD6 PLEKHH2

1.98e-0350933IPR019749
DomainB41

JAK1 FRMD6 PLEKHH2

1.98e-0350933SM00295
DomainTPR

RGPD4 NAA15 RGPD8 RGPD3

3.95e-03129934SM00028
DomainTPR_repeat

RGPD4 NAA15 RGPD8 RGPD3

4.40e-03133934IPR019734
PathwayBIOCARTA_RANBP2_PATHWAY

RGPD4 RGPD8 RGPD3

6.94e-0518643MM1549
PathwayWP_SILDENAFIL_TREATMENT

AKT1 AKT2 NOS1

1.48e-0423643M46455
PathwayKEGG_MEDICUS_VARIANT_LOSS_OF_NKX3_1_TO_PI3K_SIGNALING_PATHWAY

AKT1 AKT2

2.01e-045642M48999
PathwaySIG_IL4RECEPTOR_IN_B_LYPHOCYTES

JAK1 AKT1 AKT2

2.42e-0427643M1718
PathwayWP_LIPID_METABOLISM_PATHWAY

ACLY AKT1 AKT2

3.00e-0429643M39762
PathwayKEGG_MEDICUS_REFERENCE_MAGI_PTEN_SIGNALING_PATHWAY

AKT1 AKT2

3.01e-046642M47523
PathwayREACTOME_DEACTIVATION_OF_THE_BETA_CATENIN_TRANSACTIVATING_COMPLEX

AKT1 AKT2 CHD8

4.03e-0432643MM14975
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_PI3K_TO_PI3K_SIGNALING_PATHWAY

AKT1 AKT2

4.20e-047642M47407
PathwayKEGG_MEDICUS_REFERENCE_ACH_CHRN_PI3K_SIGNALING_PATHWAY

AKT1 AKT2

4.20e-047642M47790
PathwayKEGG_MEDICUS_VARIANT_AMPLIFIED_PDGFR_TO_PI3K_SIGNALING_PATHWAY

AKT1 AKT2

5.58e-048642M47399
PathwayKEGG_MEDICUS_VARIANT_AMPLIFIED_EGFR_TO_PI3K_SIGNALING_PATHWAY

AKT1 AKT2

5.58e-048642M47394
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_EGFR_TO_PI3K_SIGNALING_PATHWAY

AKT1 AKT2

5.58e-048642M47395
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_KIT_TO_PI3K_SIGNALING_PATHWAY

AKT1 AKT2

5.58e-048642M47404
PathwayKEGG_MEDICUS_VARIANT_EML4_ALK_FUSION_KINASE_TO_PI3K_SIGNALING_PATHWAY

AKT1 AKT2

5.58e-048642M47405
PathwayKEGG_MEDICUS_REFERENCE_P4_PR_PI3K_SIGNALING_PATHWAY

AKT1 AKT2

5.58e-048642M47803
PathwayREACTOME_RUNX2_REGULATES_GENES_INVOLVED_IN_CELL_MIGRATION

AKT1 AKT2

5.58e-048642M27806
PathwayKEGG_MEDICUS_VARIANT_TGFA_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY

AKT1 AKT2

5.58e-048642M47482
PathwayKEGG_MEDICUS_VARIANT_EGF_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY

AKT1 AKT2

5.58e-048642M47498
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_RET_TO_PI3K_SIGNALING_PATHWAY

AKT1 AKT2

5.58e-048642M47715
PathwayWP_ACUTE_VIRAL_MYOCARDITIS

JAK1 EIF4G2 AKT1 NOS1

5.94e-0485644M39776
PathwayREACTOME_PTK6_REGULATES_RTKS_AND_THEIR_EFFECTORS_AKT1_AND_DOK1

AKT1 ARAP1

7.16e-049642M27732
PathwayBIOCARTA_IFNA_PATHWAY

JAK1 IFNAR1

7.16e-049642M22056
PathwayKEGG_MEDICUS_VARIANT_AMPLIFIED_FGFR_TO_PI3K_SIGNALING_PATHWAY

AKT1 AKT2

7.16e-049642M47397
PathwayKEGG_MEDICUS_REFERENCE_EGF_EGFR_PI3K_SIGNALING_PATHWAY

AKT1 AKT2

7.16e-049642M47392
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_KRAS_NRAS_TO_PI3K_SIGNALING_PATHWAY

AKT1 AKT2

7.16e-049642M47391
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_MET_TO_PI3K_SIGNALING_PATHWAY

AKT1 AKT2

7.16e-049642M47402
PathwayKEGG_MEDICUS_REFERENCE_MEMBRANE_INITIATED_PROGESTERONE_SIGNALING_PATHWAY

AKT1 AKT2

7.16e-049642M47802
PathwayKEGG_MEDICUS_VARIANT_AMPLIFIED_MET_TO_PI3K_SIGNALING_PATHWAY

AKT1 AKT2

7.16e-049642M47490
PathwayKEGG_MEDICUS_REFERENCE_TGFA_EGFR_PI3K_SIGNALING_PATHWAY

AKT1 AKT2

7.16e-049642M47481
PathwayREACTOME_ESTROGEN_DEPENDENT_NUCLEAR_EVENTS_DOWNSTREAM_OF_ESR_MEMBRANE_SIGNALING

AKT1 AKT2

7.16e-049642MM15666
PathwayKEGG_MEDICUS_REFERENCE_ICOSLG_ICOS_PI3K_SIGNALING_PATHWAY

AKT1 AKT2

7.16e-049642M47972
PathwayREACTOME_PTK6_REGULATES_RTKS_AND_THEIR_EFFECTORS_AKT1_AND_DOK1

AKT1 ARAP1

7.16e-049642MM15482
PathwayREACTOME_NUCLEAR_PORE_COMPLEX_NPC_DISASSEMBLY

RGPD4 RGPD8 RGPD3

7.82e-0440643MM14945
PathwayWP_CATABOLISM_OF_SKELETAL_MUSCLE_IN_CACHEXIA

JAK1 AKT1 ACVR2A

7.82e-0440643M48337
PathwayREACTOME_MTOR_SIGNALLING

AKT1 EEF2K AKT2

8.41e-0441643M27000
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_SMALL_RNAS

RGPD4 RGPD8 RGPD3

8.41e-0441643MM15200
PathwayKEGG_MEDICUS_VARIANT_EGFR_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY

AKT1 AKT2

8.92e-0410642M47400
PathwayKEGG_MEDICUS_REFERENCE_HGF_MET_PI3K_SIGNALING_PATHWAY

AKT1 AKT2

8.92e-0410642M47401
PathwayKEGG_MEDICUS_REFERENCE_CD80_CD86_CD28_PI3K_SIGNALING_PATHWAY

AKT1 AKT2

8.92e-0410642M47615
PathwayREACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_NUCLEUS

AKT1 AKT2

8.92e-0410642M27095
PathwayREACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_NUCLEUS

AKT1 AKT2

8.92e-0410642MM14778
PathwayREACTOME_SUMOYLATION_OF_SUMOYLATION_PROTEINS

RGPD4 RGPD8 RGPD3

9.03e-0442643MM15039
PathwayREACTOME_MTOR_SIGNALLING

AKT1 EEF2K AKT2

9.03e-0442643MM14638
PathwayREACTOME_DEACTIVATION_OF_THE_BETA_CATENIN_TRANSACTIVATING_COMPLEX

AKT1 AKT2 CHD8

9.03e-0442643M27272
PathwayREACTOME_NCAM1_INTERACTIONS

CACNA1S COL6A5 ST8SIA4

9.03e-0442643M7169
PathwayREACTOME_TRANSPORT_OF_THE_SLBP_DEPENDANT_MATURE_MRNA

RGPD4 RGPD8 RGPD3

9.68e-0443643MM14609
PathwayKEGG_MEDICUS_ENV_FACTOR_NICOTINE_NNK_TO_PI3K_SIGNALING_PATHWAY

AKT1 AKT2

1.09e-0311642M47797
PathwayKEGG_MEDICUS_REFERENCE_KITLG_KIT_PI3K_SIGNALING_PATHWAY

AKT1 AKT2

1.09e-0311642M47403
PathwayKEGG_MEDICUS_VARIANT_BCR_ABL_FUSION_KINASE_TO_PI3K_SIGNALING_PATHWAY

AKT1 AKT2

1.09e-0311642M47406
PathwayBIOCARTA_IL4_PATHWAY

JAK1 AKT1

1.09e-0311642MM1413
PathwayBIOCARTA_IL4_PATHWAY

JAK1 AKT1

1.09e-0311642M5415
PathwayKEGG_MEDICUS_REFERENCE_IGF2_IGF1R_PI3K_SIGNALING_PATHWAY

AKT1 AKT2

1.09e-0311642M47484
PathwayKEGG_MEDICUS_REFERENCE_EREG_EGFR_PI3K_SIGNALING_PATHWAY

AKT1 AKT2

1.09e-0311642M47499
PathwayKEGG_MEDICUS_REFERENCE_NRG_ERBB4_PI3K_SIGNALING_PATHWAY

AKT1 AKT2

1.09e-0311642M47756
PathwayKEGG_MEDICUS_ENV_FACTOR_NNK_NNN_TO_PI3K_SIGNALING_PATHWAY_N01339

AKT1 AKT2

1.09e-0311642M47791
PathwayKEGG_MEDICUS_REFERENCE_AREG_EGFR_PI3K_SIGNALING_PATHWAY

AKT1 AKT2

1.09e-0311642M47501
PathwaySIG_CHEMOTAXIS

MYLK AKT1 AKT2

1.11e-0345643M5193
PathwayREACTOME_SUMOYLATION_OF_UBIQUITINYLATION_PROTEINS

RGPD4 RGPD8 RGPD3

1.25e-0347643MM14939
PathwayPID_IL6_7_PATHWAY

JAK1 PTPRE AKT1

1.25e-0347643M183
PathwayKEGG_MEDICUS_VARIANT_ERBB2_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY

AKT1 AKT2

1.30e-0312642M47393
PathwayREACTOME_HDR_THROUGH_MMEJ_ALT_NHEJ

LIG3 POLQ

1.30e-0312642M27569
PathwayREACTOME_HDR_THROUGH_MMEJ_ALT_NHEJ

LIG3 POLQ

1.30e-0312642MM15282
PathwayKEGG_MEDICUS_ENV_FACTOR_NNK_NNN_TO_PI3K_SIGNALING_PATHWAY_N01350

AKT1 AKT2

1.30e-0312642M47798
PathwayKEGG_MEDICUS_REFERENCE_CXCR4_GNAI_PI3K_BAD_SIGNALING_PATHWAY

AKT1 AKT2

1.30e-0312642M47558
PathwayKEGG_MEDICUS_PATHOGEN_HIV_GP120_TO_CXCR4_GNAI_PI3K_BAD_SIGNALING_PATHWAY

AKT1 AKT2

1.30e-0312642M47559
PathwayREACTOME_SARS_COV_2_TARGETS_HOST_INTRACELLULAR_SIGNALLING_AND_REGULATORY_PATHWAYS

AKT1 AKT2

1.30e-0312642M45022
PathwayREACTOME_REGULATION_OF_LOCALIZATION_OF_FOXO_TRANSCRIPTION_FACTORS

AKT1 AKT2

1.30e-0312642MM15657
PathwayREACTOME_REGULATION_OF_LOCALIZATION_OF_FOXO_TRANSCRIPTION_FACTORS

AKT1 AKT2

1.30e-0312642M27939
PathwayREACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL

AKT1 AKT2

1.30e-0312642MM14777
PathwayREACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING

AKT1 AKT2

1.30e-0312642MM14550
PathwayREACTOME_GENE_SILENCING_BY_RNA

RGPD4 RGPD8 RGPD3

1.42e-0349643MM14837
PathwayREACTOME_TRANSPORT_OF_MATURE_MRNAS_DERIVED_FROM_INTRONLESS_TRANSCRIPTS

RGPD4 RGPD8 RGPD3

1.50e-0350643MM14610
PathwayKEGG_MEDICUS_REFERENCE_PDGF_PDGFR_PI3K_SIGNALING_PATHWAY

AKT1 AKT2

1.53e-0313642M47398
PathwayKEGG_MEDICUS_REFERENCE_IGF_IGF1R_PI3K_SIGNALING_PATHWAY

AKT1 AKT2

1.53e-0313642M47603
PathwayREACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING

AKT1 AKT2

1.53e-0313642M549
PathwayREACTOME_SUMOYLATION_OF_DNA_REPLICATION_PROTEINS

RGPD4 RGPD8 RGPD3

1.59e-0351643MM15151
PathwaySIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES

AKT1 AKT2 PARD3

1.59e-0351643M7955
PathwayWP_FEMALE_STEROID_HORMONES_IN_CARDIOMYOCYTE_ENERGY_METABOLISM

ACLY AKT2

1.78e-0314642M48059
PathwayKEGG_MEDICUS_VARIANT_DUPLICATION_OR_MUTATION_ACTIVATED_FLT3_TO_RAS_PI3K_SIGNALING_PATHWAY

AKT1 AKT2

1.78e-0314642M47390
PathwayREACTOME_REGULATION_OF_TP53_ACTIVITY_THROUGH_ASSOCIATION_WITH_CO_FACTORS

AKT1 AKT2

1.78e-0314642MM15341
PathwayREACTOME_REGULATION_OF_TP53_ACTIVITY_THROUGH_ASSOCIATION_WITH_CO_FACTORS

AKT1 AKT2

1.78e-0314642M27638
PathwayKEGG_MEDICUS_REFERENCE_IGF_IGFR_PI3K_NFKB_SIGNALING_PATHWAY

AKT1 AKT2

1.78e-0314642M47467
PathwayKEGG_MEDICUS_REFERENCE_EGF_EGFR_PI3K_NFKB_SIGNALING_PATHWAY

AKT1 AKT2

1.78e-0314642M47536
PathwayREACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL

AKT1 AKT2

1.78e-0314642M3862
PathwayREACTOME_MITOTIC_SPINDLE_CHECKPOINT

RGPD4 RGPD8 ANAPC1 RGPD3

1.95e-03117644MM15387
PathwayREACTOME_NUCLEAR_ENVELOPE_BREAKDOWN

RGPD4 RGPD8 RGPD3

1.98e-0355643MM14917
PathwayKEGG_MEDICUS_REFERENCE_EGF_EGFR_RAS_PI3K_SIGNALING_PATHWAY

AKT1 AKT2

2.05e-0315642M47389
PathwayKEGG_MEDICUS_REFERENCE_RELN_VLDLR_PI3K_SIGNALING_PATHWAY

AKT1 AKT2

2.05e-0315642M47663
PathwayREACTOME_ACTIVATION_OF_BAD_AND_TRANSLOCATION_TO_MITOCHONDRIA

AKT1 AKT2

2.05e-0315642M26902
PathwayWP_TRANSCRIPTION_FACTORS_REGULATE_MIRNAS_RELATED_TO_CARDIAC_HYPERTROPHY

AKT1 AKT2

2.05e-0315642M39431
PathwayKEGG_MEDICUS_REFERENCE_FLT3LG_FLT3_RAS_PI3K_SIGNALING_PATHWAY

AKT1 AKT2

2.05e-0315642M47475
PathwayWP_RIOK1_AND_RIOK2_IN_EGFR_AND_PI3KMEDIATED_TUMORIGENESIS

AKT1 AKT2

2.05e-0315642M48306
PathwayKEGG_MEDICUS_REFERENCE_BCR_BCAP_CD19_PI3K_SIGNALING_PATHWAY

AKT1 AKT2

2.05e-0315642M47971
PathwayREACTOME_SUMOYLATION_OF_RNA_BINDING_PROTEINS

RGPD4 RGPD8 RGPD3

2.30e-0358643MM15149
PathwayREACTOME_SNRNP_ASSEMBLY

RGPD4 RGPD8 RGPD3

2.30e-0358643MM14736
PathwayBIOCARTA_EIF_PATHWAY

EIF4G2 EEF2K

2.34e-0316642M7721
PathwayWP_INVOLVEMENT_OF_SECRETASE_IN_NEURODEGENERATIVE_DISEASES

AKT1 AKT2

2.64e-0317642M48086
PathwayBIOCARTA_ARAP_PATHWAY

ARAP1 ARAP2

2.64e-0317642M2482
PathwayBIOCARTA_TEL_PATHWAY

AKT1 TEP1

2.64e-0317642MM1508
PathwaySA_PTEN_PATHWAY

AKT1 AKT2

2.64e-0317642M12771
Pubmed

Complex genomic rearrangements lead to novel primate gene function.

RGPD4 RGPD8 RGPD3 RGPD5

1.67e-09793415710750
Pubmed

Differential regulation of Akt/protein kinase B isoforms during cell cycle progression.

AKT1 AKT2 PARD3

1.85e-08393319166849
Pubmed

An integrin axis induces IFN-β production in plasmacytoid dendritic cells.

AKT1 AKT2 IFNAR1

1.84e-07593335878016
Pubmed

mTORC2-AKT signaling to ATP-citrate lyase drives brown adipogenesis and de novo lipogenesis.

ACLY AKT1 AKT2

3.68e-07693331996678
Pubmed

Interconversion of red opsin isoforms by the cyclophilin-related chaperone protein Ran-binding protein 2.

RGPD4 RGPD8 RGPD3

6.43e-0779339037092
Pubmed

Genomic organization, expression, and localization of murine Ran-binding protein 2 (RanBP2) gene.

RGPD4 RGPD8 RGPD3

6.43e-07793311353387
Pubmed

Microglial activation in an amyotrophic lateral sclerosis-like model caused by Ranbp2 loss and nucleocytoplasmic transport impairment in retinal ganglion neurons.

RGPD4 RGPD8 RGPD3

6.43e-07793330944974
Pubmed

Nucleoporin Nup358 drives the differentiation of myeloid-biased multipotent progenitors by modulating HDAC3 nuclear translocation.

RGPD4 RGPD8 RGPD3

6.43e-07793338838144
Pubmed

Retina-specifically expressed novel subtypes of bovine cyclophilin.

RGPD4 RGPD8 RGPD3

6.43e-0779337559465
Pubmed

Mst1, RanBP2 and eIF4G are new markers for in vivo PI3K activation in murine and human prostate.

RGPD4 RGPD8 RGPD3

6.43e-07793317372272
Pubmed

Proteostatic Remodeling of Small Heat Shock Chaperones─Crystallins by Ran-Binding Protein 2─and the Peptidyl-Prolyl cis-trans Isomerase and Chaperone Activities of Its Cyclophilin Domain.

RGPD4 RGPD8 RGPD3

6.43e-07793338657106
Pubmed

Nup358, a nucleoporin, functions as a key determinant of the nuclear pore complex structure remodeling during skeletal myogenesis.

RGPD4 RGPD8 RGPD3

6.43e-07793321205196
Pubmed

Haploinsufficiency of RanBP2 is neuroprotective against light-elicited and age-dependent degeneration of photoreceptor neurons.

RGPD4 RGPD8 RGPD3

6.43e-07793318949001
Pubmed

Selective impairment of a subset of Ran-GTP-binding domains of ran-binding protein 2 (Ranbp2) suffices to recapitulate the degeneration of the retinal pigment epithelium (RPE) triggered by Ranbp2 ablation.

RGPD4 RGPD8 RGPD3

6.43e-07793325187515
Pubmed

Localization of the Ran-GTP binding protein RanBP2 at the cytoplasmic side of the nuclear pore complex.

RGPD4 RGPD8 RGPD3

6.43e-0779338603673
Pubmed

Uncoupling phototoxicity-elicited neural dysmorphology and death by insidious function and selective impairment of Ran-binding protein 2 (Ranbp2).

RGPD4 RGPD8 RGPD3

6.43e-07793326632511
Pubmed

Differential loss of prolyl isomerase or chaperone activity of Ran-binding protein 2 (Ranbp2) unveils distinct physiological roles of its cyclophilin domain in proteostasis.

RGPD4 RGPD8 RGPD3

6.43e-07793324403063
Pubmed

Distinct and atypical intrinsic and extrinsic cell death pathways between photoreceptor cell types upon specific ablation of Ranbp2 in cone photoreceptors.

RGPD4 RGPD8 RGPD3

6.43e-07793323818861
Pubmed

Kinesin-1 and mitochondrial motility control by discrimination of structurally equivalent but distinct subdomains in Ran-GTP-binding domains of Ran-binding protein 2.

RGPD4 RGPD8 RGPD3

6.43e-07793323536549
Pubmed

Identification of RanBP2- and kinesin-mediated transport pathways with restricted neuronal and subcellular localization.

RGPD4 RGPD8 RGPD3

6.43e-07793312191015
Pubmed

Ranbp2 haploinsufficiency mediates distinct cellular and biochemical phenotypes in brain and retinal dopaminergic and glia cells elicited by the Parkinsonian neurotoxin, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).

RGPD4 RGPD8 RGPD3

6.43e-07793322821000
Pubmed

Neuroprotection resulting from insufficiency of RANBP2 is associated with the modulation of protein and lipid homeostasis of functionally diverse but linked pathways in response to oxidative stress.

RGPD4 RGPD8 RGPD3

6.43e-07793320682751
Pubmed

The nucleoporin RanBP2 tethers the cAMP effector Epac1 and inhibits its catalytic activity.

RGPD4 RGPD8 RGPD3

1.03e-06893321670213
Pubmed

Critical role of RanBP2-mediated SUMOylation of Small Heterodimer Partner in maintaining bile acid homeostasis.

RGPD4 RGPD8 RGPD3

1.03e-06893327412403
Pubmed

Mice lacking Ran binding protein 1 are viable and show male infertility.

RGPD4 RGPD8 RGPD3

1.03e-06893321310149
Pubmed

The distribution of phosphorylated SR proteins and alternative splicing are regulated by RANBP2.

RGPD4 RGPD8 RGPD3

1.03e-06893322262462
Pubmed

Zap70 and downstream RanBP2 are required for the exact timing of the meiotic cell cycle in oocytes.

RGPD4 RGPD8 RGPD3

1.03e-06893328745977
Pubmed

Resolution of sister centromeres requires RanBP2-mediated SUMOylation of topoisomerase IIalpha.

RGPD4 RGPD8 RGPD3

1.54e-06993318394993
Pubmed

Loss of Ranbp2 in motoneurons causes disruption of nucleocytoplasmic and chemokine signaling, proteostasis of hnRNPH3 and Mmp28, and development of amyotrophic lateral sclerosis-like syndromes.

RGPD4 RGPD8 RGPD3

1.54e-06993328100513
Pubmed

Association of the kinesin-binding domain of RanBP2 to KIF5B and KIF5C determines mitochondria localization and function.

RGPD4 RGPD8 RGPD3

1.54e-06993317887960
Pubmed

The docking of kinesins, KIF5B and KIF5C, to Ran-binding protein 2 (RanBP2) is mediated via a novel RanBP2 domain.

RGPD4 RGPD8 RGPD3

1.54e-06993311553612
Pubmed

The zinc finger cluster domain of RanBP2 is a specific docking site for the nuclear export factor, exportin-1.

RGPD4 RGPD8 RGPD3

1.54e-06993310601307
Pubmed

The cyclophilin-like domain mediates the association of Ran-binding protein 2 with subunits of the 19 S regulatory complex of the proteasome.

RGPD4 RGPD8 RGPD3

1.54e-0699339733766
Pubmed

Impairments in age-dependent ubiquitin proteostasis and structural integrity of selective neurons by uncoupling Ran GTPase from the Ran-binding domain 3 of Ranbp2 and identification of novel mitochondrial isoforms of ubiquitin-conjugating enzyme E2I (ubc9) and Ranbp2.

RGPD4 RGPD8 RGPD3

1.54e-06993328877029
Pubmed

The RanBP2/RanGAP1*SUMO1/Ubc9 SUMO E3 ligase is a disassembly machine for Crm1-dependent nuclear export complexes.

RGPD4 RGPD8 RGPD3

2.19e-061093327160050
Pubmed

Parkin ubiquitinates and promotes the degradation of RanBP2.

RGPD4 RGPD8 RGPD3

2.19e-061093316332688
Pubmed

Cyclophilin-related protein RanBP2 acts as chaperone for red/green opsin.

RGPD4 RGPD8 RGPD3

2.19e-06109338857542
Pubmed

Ran-dependent docking of importin-beta to RanBP2/Nup358 filaments is essential for protein import and cell viability.

RGPD4 RGPD8 RGPD3

2.19e-061093321859863
Pubmed

RanBP2 modulates Cox11 and hexokinase I activities and haploinsufficiency of RanBP2 causes deficits in glucose metabolism.

RGPD4 RGPD8 RGPD3

3.01e-061193317069463
Pubmed

An Rtn4/Nogo-A-interacting micropeptide modulates synaptic plasticity with age.

RGPD4 RGPD8 RGPD3

3.01e-061193335771867
Pubmed

T-cell receptor (TCR) signaling promotes the assembly of RanBP2/RanGAP1-SUMO1/Ubc9 nuclear pore subcomplex via PKC-θ-mediated phosphorylation of RanGAP1.

RGPD4 RGPD8 RGPD3

3.01e-061193334110283
Pubmed

Interaction of PDK1 with phosphoinositides is essential for neuronal differentiation but dispensable for neuronal survival.

AKT1 AKT2 BRSK1

4.00e-061293323275438
Pubmed

Ankyrin-G induces nucleoporin Nup358 to associate with the axon initial segment of neurons.

RGPD4 RGPD8 RGPD3

5.19e-061393331427429
Pubmed

Different functions of AKT1 and AKT2 in molecular pathways, cell migration and metabolism in colon cancer cells.

AKT1 AKT2

7.07e-06293227878243
Pubmed

BAY 1125976, a selective allosteric AKT1/2 inhibitor, exhibits high efficacy on AKT signaling-dependent tumor growth in mouse models.

AKT1 AKT2

7.07e-06293227699769
Pubmed

Akt1 and Jak1 siRNA based silencing effects on the proliferation and apoptosis in head and neck squamous cell carcinoma.

JAK1 AKT1

7.07e-06293231348981
Pubmed

Isoform-Specific Role of Akt in Oral Squamous Cell Carcinoma.

AKT1 AKT2

7.07e-06293231252679
Pubmed

Akt1 is critical for acute inflammation and histamine-mediated vascular leakage.

AKT1 AKT2

7.07e-06293219622728
Pubmed

Expression of AKT1 along with AKT2 in granulosa-lutein cells of hyperandrogenic PCOS patients.

AKT1 AKT2

7.07e-06293228271235
Pubmed

Role of Akt in cardiac growth and metabolism.

AKT1 AKT2

7.07e-06293217019809
Pubmed

Knockout of Akt1/2 suppresses the metastasis of human prostate cancer cells CWR22rv1 in vitro and in vivo.

AKT1 AKT2

7.07e-06293233377281
Pubmed

Akt2 mRNA is highly expressed in embryonic brown fat and the AKT2 kinase is activated by insulin.

AKT1 AKT2

7.07e-0629329620559
Pubmed

Akt1 and Akt2 differently regulate muscle creatine kinase and myogenin gene transcription in insulin-induced differentiation of C2C12 myoblasts.

AKT1 AKT2

7.07e-06293211861503
Pubmed

Akt regulates basic helix-loop-helix transcription factor-coactivator complex formation and activity during neuronal differentiation.

AKT1 AKT2

7.07e-06293212808085
Pubmed

Impaired expression and insulin-stimulated phosphorylation of Akt-2 in muscle of obese patients with atypical diabetes.

AKT1 AKT2

7.07e-06293215010337
Pubmed

Reducing Akt2 in retinal pigment epithelial cells causes a compensatory increase in Akt1 and attenuates diabetic retinopathy.

AKT1 AKT2

7.07e-06293236229454
Pubmed

Akt2 regulates cardiac metabolism and cardiomyocyte survival.

AKT1 AKT2

7.07e-06293216950770
Pubmed

Akt isoforms differentially regulate neutrophil functions.

AKT1 AKT2

7.07e-06293220332370
Pubmed

AKT has an anti-apoptotic role in ABCA12-deficient keratinocytes.

ABCA12 AKT1

7.07e-06293221633372
Pubmed

Molecular cloning of the akt oncogene and its human homologues AKT1 and AKT2: amplification of AKT1 in a primary human gastric adenocarcinoma.

AKT1 AKT2

7.07e-0629323037531
Pubmed

High-intensity muscle contraction-mediated increases in Akt1 and Akt2 phosphorylation do not contribute to mTORC1 activation and muscle protein synthesis.

AKT1 AKT2

7.07e-06293232078465
Pubmed

Defining Akt actions in muscle differentiation.

AKT1 AKT2

7.07e-06293223076793
Pubmed

Function of Akt/PKB signaling to cell motility, invasion and the tumor stroma in cancer.

AKT1 AKT2

7.07e-06293219110052
Pubmed

Loss of Akt1 or Akt2 delays mammary tumor onset and suppresses tumor growth rate in MTB-IGFIR transgenic mice.

AKT1 AKT2

7.07e-06293223919516
Pubmed

Cutaneous human papillomaviruses down-regulate AKT1, whereas AKT2 up-regulation and activation associates with tumors.

AKT1 AKT2

7.07e-06293217804734
Pubmed

Lack of AKT in adipocytes causes severe lipodystrophy.

AKT1 AKT2

7.07e-06293227408773
Pubmed

Isoform-specific requirement for Akt1 in the developmental regulation of cellular metabolism during lactation.

AKT1 AKT2

7.07e-06293217141631
Pubmed

PI3K/AKT Signaling in Breast Cancer Molecular Subtyping and Lymph Node Involvement.

AKT1 AKT2

7.07e-06293231781306
Pubmed

Measles virus suppresses interferon-alpha signaling pathway: suppression of Jak1 phosphorylation and association of viral accessory proteins, C and V, with interferon-alpha receptor complex.

JAK1 IFNAR1

7.07e-06293212620806
Pubmed

Akt-1 and Akt-2 Differentially Regulate the Development of Experimental Autoimmune Encephalomyelitis by Controlling Proliferation of Thymus-Derived Regulatory T Cells.

AKT1 AKT2

7.07e-06293230692211
Pubmed

Distinct actions of akt1 on skeletal architecture and function.

AKT1 AKT2

7.07e-06293224663486
Pubmed

Akt1 and akt2 play distinct roles in the initiation and metastatic phases of mammary tumor progression.

AKT1 AKT2

7.07e-06293219491266
Pubmed

Akt1 and Akt2 are required for alphabeta thymocyte survival and differentiation.

AKT1 AKT2

7.07e-06293217609365
Pubmed

Identification of functional domains in AKT responsible for distinct roles of AKT isoforms in pressure-stimulated cancer cell adhesion.

AKT1 AKT2

7.07e-06293217825284
Pubmed

Depletion of Akt1 and Akt2 Impairs the Repair of Radiation-Induced DNA Double Strand Breaks via Homologous Recombination.

AKT1 AKT2

7.07e-06293231847370
Pubmed

Unique roles of Akt1 and Akt2 in IGF-IR mediated lung tumorigenesis.

AKT1 AKT2

7.07e-06293226654940
Pubmed

Quantitative analysis of anti-apoptotic function of Akt in Akt1 and Akt2 double knock-out mouse embryonic fibroblast cells under normal and stressed conditions.

AKT1 AKT2

7.07e-06293216923802
Pubmed

Role of AMPK and Akt in triple negative breast cancer lung colonization.

AKT1 AKT2

7.07e-06293233839456
Pubmed

Akt1 and Akt2: differentiating the aktion.

AKT1 AKT2

7.07e-06293221432781
Pubmed

Molecular alterations in AKT and its protein activation in human lung carcinomas.

AKT1 AKT2

7.07e-06293222748472
Pubmed

Akt deficiency impairs normal cell proliferation and suppresses oncogenesis in a p53-independent and mTORC1-dependent manner.

AKT1 AKT2

7.07e-06293217045205
Pubmed

Akt1 and Akt2 Isoforms Play Distinct Roles in Regulating the Development of Inflammation and Fibrosis Associated with Alcoholic Liver Disease.

AKT1 AKT2

7.07e-06293231671832
Pubmed

PKB signaling and atrogene expression in skeletal muscle of aged mice.

AKT1 AKT2

7.07e-06293221551011
Pubmed

Differential phosphorylation of Akt1 and Akt2 by protein kinase CK2 may account for isoform specific functions.

AKT1 AKT2

7.07e-06293224769357
Pubmed

Distinct and specific roles of AKT1 and AKT2 in androgen-sensitive and androgen-independent prostate cancer cells.

AKT1 AKT2

7.07e-06293223567263
Pubmed

Distinct roles of Akt1 and Akt2 in regulating cell migration and epithelial-mesenchymal transition.

AKT1 AKT2

7.07e-06293216365168
Pubmed

Prognostic significance of activated Akt expression in pancreatic ductal adenocarcinoma.

AKT1 AKT2

7.07e-06293215102693
Pubmed

AKT1 and AKT2 induce distinct phosphorylation patterns in HL-1 cardiac myocytes.

AKT1 AKT2

7.07e-06293225162660
Pubmed

The Akt1 isoform is an essential mediator of ischaemic preconditioning.

AKT1 AKT2

7.07e-06293222117619
Pubmed

Akt1 deficiency delays tumor progression, vascular invasion, and distant metastasis in a murine model of thyroid cancer.

THRB AKT1

7.07e-06293221532616
Pubmed

Distinct actions of Akt1 and Akt2 in skeletal muscle differentiation.

AKT1 AKT2

7.07e-06293219142853
Pubmed

Akt1/Akt2 and mammalian target of rapamycin/Bim play critical roles in osteoclast differentiation and survival, respectively, whereas Akt is dispensable for cell survival in isolated osteoclast precursors.

AKT1 AKT2

7.07e-06293215545269
Pubmed

Loss of PKBβ/Akt2 predisposes mice to ovarian cyst formation and increases the severity of polycystic ovary formation in vivo.

AKT1 AKT2

7.07e-06293222275470
Pubmed

Specific and redundant roles of PKBα/AKT1 and PKBβ/AKT2 in human pancreatic islets.

AKT1 AKT2

7.07e-06293226318486
Pubmed

Endothelial Akt1 mediates angiogenesis by phosphorylating multiple angiogenic substrates.

AKT1 AKT2

7.07e-06293225136137
Pubmed

Differential function of Akt1 and Akt2 in human adipocytes.

AKT1 AKT2

7.07e-06293222480544
Pubmed

Par-3 family proteins in cell polarity & adhesion.

PARD3B PARD3

7.07e-06293233565714
Pubmed

Akt1 and Akt2 protein kinases differentially contribute to macrophage polarization.

AKT1 AKT2

7.07e-06293222647600
Pubmed

Akt isoform-specific inhibition of MDA-MB-231 cell proliferation.

AKT1 AKT2

7.07e-06293220688159
Pubmed

Stability and function of adult vasculature is sustained by Akt/Jagged1 signalling axis in endothelium.

AKT1 AKT2

7.07e-06293226971877
InteractionRGPD4 interactions

RGPD4 RGPD8 RGPD3 RGPD5

2.79e-0622924int:RGPD4
InteractionRGPD2 interactions

RGPD4 RGPD8 RGPD3 RGPD5

6.59e-0627924int:RGPD2
GeneFamilyPDZ domain containing

RAPGEF6 GIPC2 PARD3B PARD3 NOS1

2.16e-041526551220
GeneFamilyAnkyrin repeat domain containing|FERM domain containing

JAK1 FRMD6 PLEKHH2

7.70e-04506531293
GeneFamilyTetratricopeptide repeat domain containing|Bardet-Biedl syndrome associated|BBSome

RGPD4 RGPD8 RGPD3 RGPD5

7.80e-04115654769
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

AKT1 AKT2 PLEKHH2 ARAP1 ARAP2

8.68e-04206655682
GeneFamilyAnkyrin repeat domain containing

FANK1 ASB3 ANKRD33B ARAP1 ARAP2

1.77e-03242655403
CoexpressionGAUSSMANN_MLL_AF4_FUSION_TARGETS_B_UP

RGPD4 HEATR6 RGPD8 RGPD3

5.62e-0633934MM477
CoexpressionGSE3920_IFNB_VS_IFNG_TREATED_ENDOTHELIAL_CELL_DN

JAK1 FAM111A ACLY CHD9 NXN TRAPPC1

4.08e-05177936M6703
CoexpressionGSE3982_MAST_CELL_VS_BASOPHIL_DN

JAK1 SYNE1 KATNIP RB1CC1 ARAP2 DUSP11

7.82e-05199936M5439
CoexpressionGSE411_UNSTIM_VS_400MIN_IL6_STIM_SOCS3_KO_MACROPHAGE_UP

PTPRE EEF2K TEP1 CLSTN1 KLHL22 IFNAR1

7.82e-05199936M6001
CoexpressionGSE20366_TREG_VS_NAIVE_CD4_TCELL_HOMEOSTATIC_CONVERSION_DN

NSMF ENPP2 SYNE1 RNF213 CHD9 CHD8

7.82e-05199936M4331
CoexpressionGSE3691_CONVENTIONAL_VS_PLASMACYTOID_DC_SPLEEN_UP

FRMD6 ENPP2 ACVR2A SLC25A19 ARAP1 ARAP2

8.04e-05200936M6369
CoexpressionGSE3039_ALPHABETA_CD8_TCELL_VS_B1_BCELL_UP

SMG1 CACNA1S RAPGEF6 PTPRE ACVR2A ST8SIA4

8.04e-05200936M6447
CoexpressionGSE13229_IMM_VS_MATURE_NKCELL_UP

CCSAP MYLK N4BP2 SOX30 RNF213 ST8SIA4

8.04e-05200936M3205
CoexpressionGSE17721_LPS_VS_POLYIC_8H_BMDC_UP

NSMF SYNE1 KIAA0319L PARD3B AKT2 TRAPPC1

8.04e-05200936M3811
CoexpressionTHAKAR_PBMC_INACTIVATED_INFLUENZA_AGE_21_30YO_NONRESPONDER_7DY_UP

MOSPD2 EIF4G2 CHD9 RB1CC1 ST8SIA4

9.12e-05127935M40905
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Cadm2_(Cadm2+_state)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

LRTM1 ADTRP PARPBP CHRNA3

7.14e-0659934b2c10c4c0a750d7f49f5a813ab5d103fb07ca76b
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Cadm2_(Cadm2+_state)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

LRTM1 ADTRP PARPBP CHRNA3

7.14e-0659934bcac768e1e034e27bab7cad3c2bf09a8f0a819ad
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Cadm2_(Cadm2+_state)--|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

LRTM1 ADTRP PARPBP CHRNA3

7.14e-0659934f9b9464f4d786991aad01b47e2a8fd33f889c2e2
ToppCell3'_v3-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

SMG1 NLRP9 ABCA12 RNF213 ARAP2

1.43e-0514793594998bc40f5c08295cfe3bdcbe43f13b1e564b3d
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_T_CD4/8-lo-Trm_Tgd|lymph-node_spleen / Manually curated celltypes from each tissue

GTF2F2 RGPD3 EEF2K PLEKHH2 TEP1

1.85e-05155935b0e456c4915076e1d38282e116a6eb3230ae80dc
ToppCellLPS_only-Myeloid-Monocytes,_Macrophages-T-cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CCSAP ZNF254 ZC2HC1C PARPBP TRAPPC1

2.03e-0515893591d8c93af328c3bbebe1d8f019b94849ebc548c0
ToppCellTCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma-9|TCGA-Bladder / Sample_Type by Project: Shred V9

FRMD6 ABCA12 CLSTN1 FBXO34 IFNAR1

2.97e-05171935adbcfa4bf6bc1c604535a24435924cdb091e2dd7
ToppCellILEUM-non-inflamed-(3)_MNP-(3)_mature_DC|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

LRRIQ3 MYO5B ADTRP ANKRD33B ARAP2

2.97e-05171935341f9f79c1ed654ab347e25dc4936f89ffdf9617
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

SMG1 RAPGEF6 SYNE1 RNF213 ARAP2

2.97e-051719352e9a20f8980b78325c52065a9c14ab3656267c05
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L6_LHX6_GLP1R|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MYO5B PARD3B COL6A5 ST8SIA4 NOS1

3.50e-051779352b675840b7d2bb536c2c600936733bd9e97e7120
ToppCellCOVID-19-kidney-Epi_(Mes)|COVID-19 / Disease (COVID-19 only), tissue and cell type

THRB MYLK PARD3B PARD3 ANKRD33B

3.59e-05178935544379f5a6145429762258d426b876bb36c112f5
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT1-AT1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MYO5B PARD3B PARD3 NXN ARAP2

4.21e-0518493557c792e6e2fedba25d3350ffe649fd74750b579d
ToppCelldroplet-Marrow-nan-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMG1 NSD1 SMARCC1 CHD9 ST8SIA4

4.21e-051849351154a5ad7b8512272b7476f949ddac350910bfb7
ToppCellCOVID-19-Endothelial_cells-Arterial_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

GIPC2 ENPP2 NXN NOS1 ANKRD33B

4.21e-051849350f19494789f38ab1a420545e15e748ca7eb345c3
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MYO5B PARD3B PARD3 NXN ARAP2

4.21e-05184935d7bd0f0c607bade67c99e9fb3578a570298bf926
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

THRB SYNE1 PARD3B PLEKHH2 NXN

4.32e-0518593534fcfd635c828dad9643bbf1c908d79282d6f5d9
ToppCellfacs-Thymus-nan-3m-Lymphocytic-DN4_thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JAK1 RAPGEF6 ACLY EIF4G2 ARAP2

4.32e-05185935a2cae8c657e4f4d121476798e424876f7e247973
ToppCellfacs-Thymus-nan-3m-Lymphocytic-DN4_thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JAK1 RAPGEF6 ACLY EIF4G2 ARAP2

4.32e-05185935d50406a9a5b8d75110ba5985741aa2293950c543
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

THRB SYNE1 PARD3B PLEKHH2 NXN

4.32e-051859358816f2909ed11833ff3d0ed96b9cb6d6fe9e1578
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

THRB SYNE1 PLEKHH2 NXN ANKRD33B

4.66e-05188935b21e93a70583c30d05c0833cd3d4d4bca44a039e
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SYNE1 PARD3B PLEKHH2 PARD3 ANKRD33B

4.66e-0518893563a4b25a0a6e05f80f1a6dd91b817f3cf49e6b68
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

THRB SYNE1 PLEKHH2 NXN ANKRD33B

4.66e-05188935874404a4fd9aa42873f6c53dc42da22d3b0fdb9e
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51|PBMC_fresh-frozen / Compartment, severity and other cell annotations on 10x 3' data (130k)

SMG1 SYNE1 RNF213 UQCRB RGPD5

4.78e-051899350e8d1be3c406d1a393e18faccfe89116a8f82bcf
ToppCellnucseq-Epithelial-Epithelial_Alveolar|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MYO5B SYNE1 PARD3B PARD3 NXN

5.41e-0519493553f3e49e91b1096f3226010e2de767efb490dfe4
ToppCellnucseq-Epithelial|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MYO5B SYNE1 PARD3B PARD3 NXN

5.54e-051959359406866f99555198a9be311fbd65751b70f35446
ToppCellLPS_IL1RA_TNF|World / Treatment groups by lineage, cell group, cell type

MYLK SYNE1 CHD9 COL6A5 PLEKHH2

5.82e-051979350a6550dce156fc81f15b1e7830d331ca50d87d06
ToppCellmild-low-quality_cells|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SMG1 SYNE1 RNF213 ARAP2 RGPD5

5.82e-05197935e4331969bd911d1ebb5453f40a7057297b5389b4
ToppCellParenchymal-NucSeq-Immune_Myeloid-Macrophage_alveolar-Macro_alv_dividing|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

BRSK1 ADTRP POLQ PARPBP CHRNA3

5.82e-05197935d669d90c3f9e98b41bcbc49dbdc5698e0b42597c
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

THRB MYLK ENPP2 PARD3B PLEKHH2

5.82e-051979350034bae02ee7fcfea520d453ca3c842ab6963b12
ToppCellCOVID-19-Fibroblasts|COVID-19 / group, cell type (main and fine annotations)

MYLK FRMD6 PARD3B PLEKHH2 PARD3

5.82e-05197935fb847f2277609c31fffcdf49517243ce0684facf
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

THRB MYLK ENPP2 PARD3B PLEKHH2

5.82e-0519793511a4c417f035e554431a8f03be13b5eefa3530c0
ToppCellfacs-Tongue-nan-3m-Epithelial|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMG1 DSC3 EIF4G2 RB1CC1 ARAP2

5.96e-051989352f03f8897dd7cce6d8296638e14e11ec16bcf624
ToppCellnormal_Lung-Fibroblasts-COL13A1+_matrix_FBs|Fibroblasts / Location, Cell class and cell subclass

MYLK ENPP2 COL6A5 NHLRC3 PLEKHH2

5.96e-05198935e0e47cf65774191981840b22905b2094b95abe0f
ToppCellfacs-Tongue-nan-3m|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMG1 DSC3 EIF4G2 RB1CC1 ARAP2

5.96e-05198935f2a4057f038ef7225a5b98a7ab068c30dff4eadd
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SMG1 SYNE1 RNF213 ARAP2 RGPD5

6.10e-05199935f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCellfacs-Tongue-nan-3m-Epithelial-nan|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMG1 DSC3 EIF4G2 RB1CC1 CLSTN1

6.10e-051999358d50e1ee58710d896c0204937331d9f4dcd38de0
ToppCellmild-gd_T|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

JAK1 SMG1 SYNE1 RNF213 ARAP2

6.25e-05200935109f673a4967ffa52270a0b4f818b3461288db44
DiseaseCHARGE syndrome (implicated_via_orthology)

CHD9 CHD8

1.91e-047902DOID:0050834 (implicated_via_orthology)
Diseasemicrocephaly (is_implicated_in)

NSD1 SLC25A19

2.55e-048902DOID:10907 (is_implicated_in)
Diseasedevelopmental disorder of mental health (implicated_via_orthology)

NAA15 PARD3B PARD3

4.57e-0449903DOID:0060037 (implicated_via_orthology)
Diseaseprostate cancer (is_implicated_in)

JAK1 THRB AKT1 AKT2

4.61e-04117904DOID:10283 (is_implicated_in)
DiseaseGastrointestinal Diseases

MYLK CHD8

5.95e-0412902C0017178
DiseaseFunctional Gastrointestinal Disorders

MYLK CHD8

5.95e-0412902C0559031
DiseaseCholera Infantum

MYLK CHD8

5.95e-0412902C1565321
DiseaseMental Retardation, Psychosocial

NAA15 NSD1 CHD8 CAPN10

8.81e-04139904C0025363
DiseaseProfound Mental Retardation

NAA15 NSD1 CHD8 CAPN10

8.81e-04139904C0020796
DiseaseMental deficiency

NAA15 NSD1 CHD8 CAPN10

8.81e-04139904C0917816
Diseaseamyotrophic lateral sclerosis, age at onset

KDM4A ARAP2

9.41e-0415902EFO_0004847, MONDO_0004976
Diseaseimpotence (implicated_via_orthology)

AKT1 NOS1

9.41e-0415902DOID:1875 (implicated_via_orthology)
Diseaseinherited metabolic disorder (is_implicated_in)

UQCRB SLC25A19

9.41e-0415902DOID:655 (is_implicated_in)
DiseaseMammary Carcinoma, Human

ALKBH8 DSC3 JMJD6 SYNE1 AKT1 AKT2 RB1CC1

1.14e-03525907C4704874
DiseaseMammary Neoplasms, Human

ALKBH8 DSC3 JMJD6 SYNE1 AKT1 AKT2 RB1CC1

1.14e-03525907C1257931
DiseaseMammary Neoplasms

ALKBH8 DSC3 JMJD6 SYNE1 AKT1 AKT2 RB1CC1

1.16e-03527907C1458155
Diseasecongenital heart disease (implicated_via_orthology)

NAA15 CHD9 CHD8

1.24e-0369903DOID:1682 (implicated_via_orthology)
DiseaseBreast Carcinoma

ALKBH8 DSC3 JMJD6 SYNE1 AKT1 AKT2 RB1CC1

1.31e-03538907C0678222
DiseaseLung Neoplasms

SOX30 SMARCC1 AKT1 TEP1 CHRNA3

1.33e-03265905C0024121
DiseaseMalignant neoplasm of lung

SOX30 SMARCC1 AKT1 TEP1 CHRNA3

1.35e-03266905C0242379
DiseaseParkinson's disease (implicated_via_orthology)

GIPC2 EIF4G2 AKT1 AKT2

1.38e-03157904DOID:14330 (implicated_via_orthology)
Diseasecancer (implicated_via_orthology)

FRMD6 SMARCC1 AKT1 AKT2 TRAPPC1

1.40e-03268905DOID:162 (implicated_via_orthology)
Diseasestomach cancer (is_implicated_in)

JAK1 TEP1 CHRNA3

1.41e-0372903DOID:10534 (is_implicated_in)
Diseaserenovascular hypertension (biomarker_via_orthology)

EIF4G2 NOS1

1.52e-0319902DOID:1591 (biomarker_via_orthology)
DiseasePancreatic carcinoma

TCHP AKT2

1.52e-0319902C0235974
DiseaseAmphetamine-Related Disorders

MYO5B AKT1 NOS1

1.58e-0375903C0236733
DiseaseAmphetamine Abuse

MYO5B AKT1 NOS1

1.58e-0375903C0236807
DiseaseAmphetamine Addiction

MYO5B AKT1 NOS1

1.58e-0375903C0236804
Diseaseprostate adenocarcinoma (is_implicated_in)

AKT1 AKT2

1.69e-0320902DOID:2526 (is_implicated_in)
Diseaseleft atrial function

GDF6 UQCRB

1.86e-0321902EFO_0004294
Diseasesystemising measurement

ASB3 CLSTN1

1.86e-0321902EFO_0010221
DiseaseBREAST CANCER

AKT1 RB1CC1

1.86e-0321902114480
DiseaseNasopharyngeal carcinoma

SYNE1 AKT2

2.04e-0322902C2931822
Diseasemalignant astrocytoma (is_marker_for)

AKT1 AKT2

2.23e-0323902DOID:3069 (is_marker_for)
Diseaselung adenocarcinoma (is_marker_for)

SOX30 EEF2K CHRNA3

2.26e-0385903DOID:3910 (is_marker_for)
DiseaseIntellectual Disability

ALKBH8 NAA15 SYNE1 NSD1 CHD8 CAPN10

2.49e-03447906C3714756
Diseasediet measurement, bilirubin measurement

AADACL3 EIF4G2

2.85e-0326902EFO_0004570, EFO_0008111
Diseasealcohol use disorder (implicated_via_orthology)

SMARCC1 AKT1 AKT2 CHRNA3

3.04e-03195904DOID:1574 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
IVKEGWLHKRGEYIK

AKT1

6

P31749
VIKEGWLHKRGEYIK

AKT2

6

P31751
VHYNGVLAAKLWRKK

EPB42

516

P16452
IHKADWIRKYNPDTL

CHD8

1546

Q9HCK8
EWAIIKAPGYKHDIK

CHRNA3

206

P32297
WLRKGYIKHKPDQMT

ALKBH8

211

Q96BT7
LYGSIKVPHWTKKQL

ABCA12

1441

Q86UK0
VVVHKKKRPVLRDYW

ACVR2A

431

P27037
KKRPVLRDYWQKHAG

ACVR2A

436

P27037
YWKLQKKEHPPEVSR

FBXO34

6

Q9NWN3
EVKPKILANGARWKY

ADTRP

31

Q96IZ2
VGWRHYDVAKKLKEL

GIPC2

171

Q8TF65
FWLPLLEKVYAKVHG

CAPN10

146

Q9HC96
QHEYDIWPPAGKERK

ARAP2

1536

Q8WZ64
KIKENKHPFALYGWG

CCSAP

176

Q6IQ19
SEEKKYRPAEFHWKL

CLSTN1

436

O94985
YKKRLEDLGVPVTWH

AADACL3

356

Q5VUY0
GHLQIPKWRYKEAKE

ANKRD33B

451

A6NCL7
GKKPHYREIVWVKVG

NSD1

1751

Q96L73
LKHQILPKEQWTKYE

UQCRB

71

P14927
GRSVHYWKKVLPLLK

RGPD5

601

Q99666
GRSVHYWKKVLPLLK

RGPD8

601

O14715
VWRHSPKKQKNGYEK

JAK1

126

P23458
TWKYLLHEKLNLPVE

PARPBP

66

Q9NWS1
HLLKQIKVKGPRYWE

ANAPC1

1661

Q9H1A4
KHYREWAGALVKDGK

RB1CC1

511

Q8TDY2
KTREKGPGYWVKIHH

PARD3B

36

Q8TEW8
LKERKEEKCHQYWPD

PTPRE

236

P23469
KWYRILKQEHPELAV

JMJD6

311

Q6NYC1
LKKVQPWHAGQYEIL

MYLK

781

Q15746
WKGKDLLRIPHELYQ

LRTM1

216

Q9HBL6
EKAVIWPQYVKDRIH

GHITM

111

Q9H3K2
QYHWEELKGPLREEK

KIAA0319L

441

Q8IZA0
KLWNYAKTPHRGVKE

KATNIP

1501

O60303
GVIYKIKLRHDNSKW

LOXHD1

1316

Q8IVV2
LKRNPGNHLYKWKQI

IFNAR1

266

P17181
TKVWNQIKPYIRHKD

HEATR6

561

Q6AI08
VRKFQPERYKLWKAG

KDM4A

321

O75164
IERKLNVYHKGAKIW

NSMF

391

Q6X4W1
DVKGTYEPGKRHWLK

LIG3

661

P49916
RHWLKVKKDYLNEGA

LIG3

671

P49916
YKWIKDNISPKLHVD

EIF4G2

751

P78344
KIYKHAGNIKEAARW

NAA15

416

Q9BXJ9
FGIKRPEHKKLYSWQ

PLEKHH2

341

Q8IVE3
IRHPKFEWFKDLGLK

NOS1

551

P29475
GRSVHYWKKVLPLLK

RGPD3

601

A6NKT7
WVVSKRGKDYILKHI

FRMD6

186

Q96NE9
KAQAKYKEWLPHLLV

ASB3

386

Q9Y575
RKDLEKWLKEHPGYV

CHD9

2506

Q3L8U1
DQAKYLNPLLGEWKH

KLHL22

316

Q53GT1
LRYKKLHDPKGWITI

DSC3

506

Q14574
KKKGGNHIPERWKDY

DUSP11

71

O75319
WAEYDPEAKGRIKHL

CACNA1S

1406

Q13698
ILLDIKQRHKPWYEE

FAM111A

581

Q96PZ2
LANWGLPKAVLEKYH

POLQ

71

O75417
RTHKPDWNYIIKFVK

COL6A5

2471

A8TX70
EKRLSLEQIQKHPWY

BRSK1

271

Q8TDC3
AKLWGEEYNRHKPPK

EEF2K

191

O00418
RWHVARKPLDVYKKP

ENPP2

451

Q13822
KAIAKDPNYWIQVHR

PARD3

36

Q8TEW0
ELYWDLEKKAKRQGP

FANK1

26

Q8TC84
KKPLHVNFKELGWDD

GDF6

356

Q6KF10
DKEGNKLFWIRVKYH

MOSPD2

101

Q8NHP6
KGIHKNTWELKPEYR

GTF2F2

226

P13984
GRSVHYWKKVLPLLK

RGPD4

601

Q7Z3J3
RGTWEKLPSKYEKHL

RAPGEF6

966

Q8TEU7
KQWKDLQGEAPYHLL

SYNE1

1006

Q8NF91
DMPWLALPYKEKHRK

NXN

106

Q6DKJ4
YPKAIFQKHRIEQWK

SMG1

2651

Q96Q15
WPFPKDLNGKAVKYH

ST8SIA4

301

Q92187
ALKEKEEPHYIEIWK

SECISBP2

811

Q96T21
QLDSVRVWLGKHYKK

SMARCC1

51

Q92922
QKIKEKHREEFPGWV

SOX30

391

O94993
QKRLKQGLYRHPWDD

ACLY

1076

P53396
HRPEKEWPIKSLKVY

ARAP1

1331

Q96P48
AKLLDKHYPGKQAWE

NLRP9

56

Q7RTR0
KKYKLWGLHIPSDQE

STK31

141

Q9BXU1
ALEPWKHYVPIKRNL

POGLUT3

406

Q7Z4H8
VKRYLWQHLKKHVVP

RNF213

586

Q63HN8
WHRKKQAGIPKEEEY

TRAPPC1

21

Q9Y5R8
KLRVHKARQWKYDGE

TEP1

636

Q99973
TEKILYRLDVGWPKH

NHLRC3

41

Q5JS37
GSHWKQKRKFLPEDI

THRB

236

P10828
EQLLYEHWKKNNPKL

TCHP

136

Q9BT92
IKGKRHWYEALPQAV

TECPR2

881

O15040
KELILDKVYTHPKWN

ZC2HC1C

61

Q53FD0
RGEWKKLEPFQKELY

ZNF483

181

Q8TF39
ELDNPHKQKAWKIYP

TPTE2

496

Q6XPS3
YKPPGLKWKHLRDTV

TRUB2

16

O95900
PKGQKYECAKRWNVH

TOPBP1

246

Q92547
HLYKWAIPAEGKKNE

SLC25A19

201

Q9HC21
KRIHTGEQPYKWEKF

ZNF254

621

O75437
PETNIKGKLAYWKHN

LRRIQ3

276

A6PVS8
RGWLQKVKYHRLKGA

MYO5B

776

Q9ULV0
QKHKYKVLFREPDTW

N4BP2

531

Q86UW6