Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionG protein-coupled receptor activity

OR10G6 OR51A4 OR51A2 TAS2R9 OR10A7 ADRA2A ADRA2B HTR2A GPR174 HTR2C OR4N5 OR4Q2 GPR153 GPR75 AGTR2 HCAR1 OR1D5 OR2V1 OR3A3 TAAR9 CCR7 CCR8 TAS2R39 OR56A1 OR2V2 GNRHR GPR119 OR4A4P CXCR2

3.34e-178849429GO:0004930
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

OR10G6 OR51A4 OR51A2 TAS2R9 OR10A7 ADRA2A ADRA2B HTR2A GPR174 HTR2C OR4N5 OR4Q2 GPR153 GPR75 AGTR2 HCAR1 TMEM63B OR1D5 PTCH2 OR2V1 OR3A3 IL20RB TAAR9 CCR7 CCR8 TAS2R39 OR56A1 OR2V2 GNRHR GPR119 OR4A4P CHRNB4 CXCR2

7.87e-1613539433GO:0004888
GeneOntologyMolecularFunctiontransmembrane transporter activity

SLC37A1 SLC6A8 SLC6A9 SLC9A9 CLCA4 SLC22A25 TMC1 TRPM5 MFSD14B SLC16A1 SLC16A2 SLC10A5 KCNV2 SPNS2 ATP6V0A4 SLC19A3 SLC28A2 TMEM63B SLC4A4 MFSD4B SLC18B1 SLC7A10 SLC29A1 ABCA9 SLC47A2 SLC2A11 SLC38A8 CHRNB4 ATP6V0A2 TPCN1 SLC16A10

1.02e-1511809431GO:0022857
GeneOntologyMolecularFunctiontransporter activity

SLC37A1 SLC6A8 SLC6A9 SLC9A9 CLCA4 SLC22A25 TMC1 TRPM5 MFSD14B SLC16A1 SLC16A2 SLC10A5 KCNV2 SPNS2 ATP6V0A4 SLC19A3 SLC28A2 TMEM63B SLC4A4 MFSD4B SLC18B1 SLC7A10 SLC29A1 ABCA9 SLC47A2 SLC2A11 SLC38A8 CHRNB4 ATP6V0A2 TPCN1 SLC16A10

1.15e-1412899431GO:0005215
GeneOntologyMolecularFunctionactive transmembrane transporter activity

SLC37A1 SLC6A8 SLC6A9 SLC9A9 SLC22A25 SLC16A1 SLC16A2 SLC10A5 ATP6V0A4 SLC28A2 SLC4A4 MFSD4B SLC18B1 SLC29A1 ABCA9 SLC47A2 ATP6V0A2 SLC16A10

7.89e-124779418GO:0022804
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC37A1 SLC6A8 SLC6A9 SLC9A9 SLC22A25 SLC16A1 SLC16A2 SLC10A5 SLC28A2 SLC4A4 MFSD4B SLC18B1 SLC29A1 SLC47A2 SLC16A10

8.36e-122969415GO:0015291
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

SLC6A8 SLC6A9 SLC9A9 TMC1 TRPM5 SLC16A1 SLC10A5 KCNV2 ATP6V0A4 SLC28A2 TMEM63B SLC4A4 SLC18B1 SLC29A1 SLC47A2 CHRNB4 ATP6V0A2 TPCN1

1.67e-096649418GO:0008324
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

SLC37A1 SLC6A8 SLC6A9 SLC9A9 CLCA4 TMC1 TRPM5 SLC16A1 SLC10A5 KCNV2 ATP6V0A4 SLC28A2 TMEM63B SLC4A4 SLC18B1 SLC29A1 SLC47A2 ATP6V0A2 TPCN1

2.02e-097589419GO:0015318
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

SLC6A8 SLC6A9 SLC9A9 CLCA4 TMC1 TRPM5 SLC16A1 SLC10A5 KCNV2 ATP6V0A4 SLC28A2 TMEM63B SLC4A4 SLC18B1 SLC29A1 SLC47A2 CHRNB4 ATP6V0A2 TPCN1

4.22e-097939419GO:0015075
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

SLC6A8 SLC6A9 SLC9A9 TMC1 TRPM5 SLC16A1 SLC10A5 KCNV2 ATP6V0A4 SLC28A2 TMEM63B SLC4A4 SLC18B1 SLC29A1 SLC47A2 ATP6V0A2 TPCN1

5.03e-096279417GO:0022890
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

SLC37A1 SLC6A8 SLC6A9 SLC22A25 SLC16A1 SLC16A2 SLC10A5 SLC19A3 SLC4A4 SLC7A10 SLC38A8 SLC16A10

1.30e-082939412GO:0008514
GeneOntologyMolecularFunctionactive monoatomic ion transmembrane transporter activity

SLC6A8 SLC6A9 SLC9A9 SLC16A1 SLC10A5 ATP6V0A4 SLC28A2 SLC4A4 SLC18B1 SLC29A1 SLC47A2 ATP6V0A2

1.75e-083019412GO:0022853
GeneOntologyMolecularFunctioncarboxylic acid transmembrane transporter activity

SLC6A8 SLC6A9 SLC22A25 SLC16A1 SLC16A2 SLC10A5 SLC19A3 SLC7A10 SLC38A8 SLC16A10

4.89e-082079410GO:0046943
GeneOntologyMolecularFunctionorganic acid transmembrane transporter activity

SLC6A8 SLC6A9 SLC22A25 SLC16A1 SLC16A2 SLC10A5 SLC19A3 SLC7A10 SLC38A8 SLC16A10

5.12e-082089410GO:0005342
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SLC6A8 SLC6A9 SLC9A9 TRPM5 SLC10A5 SLC28A2 SLC4A4 SLC29A1 TPCN1

1.14e-07171949GO:0015081
GeneOntologyMolecularFunctionsymporter activity

SLC6A8 SLC6A9 SLC16A1 SLC10A5 SLC28A2 SLC4A4 MFSD4B SLC29A1

5.42e-07150948GO:0015293
GeneOntologyMolecularFunctionolfactory receptor activity

OR10G6 OR51A4 OR51A2 OR10A7 OR4N5 OR4Q2 OR1D5 OR2V1 OR3A3 OR56A1 OR2V2 OR4A4P

8.48e-074319412GO:0004984
GeneOntologyMolecularFunctionG protein-coupled amine receptor activity

ADRA2A ADRA2B HTR2A HTR2C TAAR9

1.36e-0641945GO:0008227
GeneOntologyMolecularFunctionsolute:monoatomic cation symporter activity

SLC6A8 SLC6A9 SLC16A1 SLC10A5 SLC28A2 SLC4A4 SLC29A1

1.49e-06119947GO:0015294
GeneOntologyMolecularFunctionsolute:sodium symporter activity

SLC6A8 SLC6A9 SLC10A5 SLC28A2 SLC4A4 SLC29A1

2.26e-0681946GO:0015370
GeneOntologyMolecularFunctionorganic cation transmembrane transporter activity

SLC6A8 SLC6A9 SLC19A3 SLC7A10 SLC47A2 SLC16A10

2.61e-0683946GO:0015101
GeneOntologyMolecularFunctionC-C chemokine receptor activity

GPR75 CCR7 CCR8 CXCR2

3.81e-0623944GO:0016493
GeneOntologyMolecularFunctionmonocarboxylic acid transmembrane transporter activity

SLC6A8 SLC22A25 SLC16A1 SLC16A2 SLC10A5 SLC16A10

4.19e-0690946GO:0008028
GeneOntologyMolecularFunctionG protein-coupled chemoattractant receptor activity

GPR75 CCR7 CCR8 CXCR2

6.36e-0626944GO:0001637
GeneOntologyMolecularFunctionchemokine receptor activity

GPR75 CCR7 CCR8 CXCR2

6.36e-0626944GO:0004950
GeneOntologyMolecularFunctionamino acid transmembrane transporter activity

SLC6A8 SLC6A9 SLC16A2 SLC7A10 SLC38A8 SLC16A10

1.02e-05105946GO:0015171
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

SLC6A8 SLC6A9 SLC9A9 TMC1 TRPM5 SLC10A5 KCNV2 SLC28A2 SLC4A4 SLC29A1 TPCN1

1.18e-054659411GO:0046873
GeneOntologyMolecularFunction1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding

HTR2A HTR2C

2.19e-052942GO:0071886
GeneOntologyMolecularFunctionalpha2-adrenergic receptor activity

ADRA2A ADRA2B

6.56e-053942GO:0004938
GeneOntologyMolecularFunctionGq/11-coupled serotonin receptor activity

HTR2A HTR2C

6.56e-053942GO:0001587
GeneOntologyMolecularFunctionsecondary active monocarboxylate transmembrane transporter activity

SLC6A8 SLC16A1 SLC10A5

9.27e-0519943GO:0015355
GeneOntologyMolecularFunctioncytokine receptor activity

GPR75 IL20RB CCR7 CCR8 CXCR2

9.51e-0597945GO:0004896
GeneOntologyMolecularFunctionnucleoside:sodium symporter activity

SLC28A2 SLC29A1

1.31e-044942GO:0005415
GeneOntologyMolecularFunctionpurine nucleoside transmembrane transporter activity

SLC28A2 SLC29A1

1.31e-044942GO:0015211
GeneOntologyMolecularFunctionnucleobase:monoatomic cation symporter activity

SLC28A2 SLC29A1

1.31e-044942GO:0015391
GeneOntologyMolecularFunctionpyrimidine- and adenosine-specific:sodium symporter activity

SLC28A2 SLC29A1

1.31e-044942GO:0015389
GeneOntologyMolecularFunctionC-C chemokine binding

CCR7 CCR8 CXCR2

1.90e-0424943GO:0019957
GeneOntologyMolecularFunctionproton transmembrane transporter activity

SLC9A9 SLC16A1 ATP6V0A4 SLC18B1 SLC47A2 ATP6V0A2

2.64e-04188946GO:0015078
GeneOntologyMolecularFunctionuridine transmembrane transporter activity

SLC28A2 SLC29A1

3.25e-046942GO:0015213
GeneOntologyMolecularFunctionepinephrine binding

ADRA2A ADRA2B

3.25e-046942GO:0051379
GeneOntologyMolecularFunctionalpha-adrenergic receptor activity

ADRA2A ADRA2B

3.25e-046942GO:0004936
GeneOntologyMolecularFunctionL-amino acid transmembrane transporter activity

SLC6A9 SLC7A10 SLC38A8 SLC16A10

3.52e-0471944GO:0015179
GeneOntologyMolecularFunctionpyrimidine nucleobase transmembrane transporter activity

SLC28A2 SLC29A1

4.53e-047942GO:0005350
GeneOntologyMolecularFunctionantiporter activity

SLC37A1 SLC9A9 SLC4A4 SLC18B1 SLC47A2

4.92e-04138945GO:0015297
GeneOntologyMolecularFunctionchemokine binding

CCR7 CCR8 CXCR2

4.98e-0433943GO:0019956
GeneOntologyMolecularFunctionorganic acid:sodium symporter activity

SLC6A8 SLC6A9 SLC10A5

5.93e-0435943GO:0005343
GeneOntologyMolecularFunctionpyrimidine nucleoside transmembrane transporter activity

SLC28A2 SLC29A1

6.03e-048942GO:0015214
GeneOntologyMolecularFunctionthyroid hormone transmembrane transporter activity

SLC16A2 SLC16A10

7.73e-049942GO:0015349
GeneOntologyMolecularFunctionadrenergic receptor activity

ADRA2A ADRA2B

9.63e-0410942GO:0004935
GeneOntologyMolecularFunctionpurine nucleobase transmembrane transporter activity

SLC28A2 SLC29A1

9.63e-0410942GO:0005345
GeneOntologyMolecularFunctionnucleoside transmembrane transporter activity

SLC28A2 SLC29A1

9.63e-0410942GO:0005337
GeneOntologyMolecularFunctiongated channel activity

CLCA4 TMC1 TRPM5 KCNV2 TMEM63B CHRNB4 TPCN1

1.01e-03334947GO:0022836
GeneOntologyMolecularFunctionimmune receptor activity

GPR75 IL20RB CCR7 CCR8 CXCR2

1.10e-03165945GO:0140375
GeneOntologyMolecularFunctionnucleobase transmembrane transporter activity

SLC28A2 SLC29A1

1.17e-0311942GO:0015205
GeneOntologyMolecularFunctioncatecholamine binding

ADRA2A ADRA2B

1.65e-0313942GO:1901338
GeneOntologyMolecularFunctionserotonin binding

HTR2A HTR2C

1.65e-0313942GO:0051378
GeneOntologyMolecularFunctionazole transmembrane transporter activity

SLC19A3 SLC28A2

1.92e-0314942GO:1901474
GeneOntologyMolecularFunctionligand-gated monoatomic ion channel activity

CLCA4 TRPM5 TMEM63B CHRNB4 TPCN1

2.19e-03193945GO:0015276
GeneOntologyMolecularFunctionmonocarboxylate:sodium symporter activity

SLC6A8 SLC10A5

2.21e-0315942GO:0140161
GeneOntologyMolecularFunctionligand-gated channel activity

CLCA4 TRPM5 TMEM63B CHRNB4 TPCN1

2.40e-03197945GO:0022834
GeneOntologyMolecularFunctioncarbohydrate derivative transmembrane transporter activity

SLC37A1 SLC28A2 SLC29A1

2.71e-0359943GO:1901505
GeneOntologyMolecularFunctionmechanosensitive monoatomic ion channel activity

TMC1 TMEM63B

3.19e-0318942GO:0008381
GeneOntologyMolecularFunctionligand-gated monoatomic cation channel activity

TRPM5 TMEM63B CHRNB4 TPCN1

4.34e-03140944GO:0099094
GeneOntologyMolecularFunctionneurotransmitter transmembrane transporter activity

SLC28A2 SLC29A1

4.34e-0321942GO:0005326
GeneOntologyMolecularFunctionamine binding

HTR2A HTR2C

4.34e-0321942GO:0043176
GeneOntologyMolecularFunctionG protein-coupled serotonin receptor activity

HTR2A HTR2C

4.76e-0322942GO:0004993
GeneOntologyMolecularFunctionamino acid:sodium symporter activity

SLC6A8 SLC6A9

5.20e-0323942GO:0005283
GeneOntologyMolecularFunctionmonoatomic cation channel activity

TMC1 TRPM5 KCNV2 TMEM63B CHRNB4 TPCN1

5.65e-03343946GO:0005261
GeneOntologyMolecularFunctionATPase activity, coupled to transmembrane movement of ions, rotational mechanism

ATP6V0A4 ATP6V0A2

5.66e-0324942GO:0044769
GeneOntologyMolecularFunctionproton-transporting ATPase activity, rotational mechanism

ATP6V0A4 ATP6V0A2

5.66e-0324942GO:0046961
GeneOntologyMolecularFunctionATPase-coupled ion transmembrane transporter activity

ATP6V0A4 ATP6V0A2

5.66e-0324942GO:0042625
GeneOntologyMolecularFunctionmonoatomic ion channel activity

CLCA4 TMC1 TRPM5 KCNV2 TMEM63B CHRNB4 TPCN1

5.96e-03459947GO:0005216
GeneOntologyMolecularFunctionD-glucose transmembrane transporter activity

MFSD4B SLC2A11

6.13e-0325942GO:0055056
GeneOntologyMolecularFunctionhexose transmembrane transporter activity

MFSD4B SLC2A11

6.13e-0325942GO:0015149
GeneOntologyMolecularFunctioncytokine binding

IL20RB CCR7 CCR8 CXCR2

6.49e-03157944GO:0019955
GeneOntologyMolecularFunctioncalcium-activated cation channel activity

TRPM5 TMEM63B

7.13e-0327942GO:0005227
GeneOntologyMolecularFunctionmonosaccharide transmembrane transporter activity

MFSD4B SLC2A11

7.13e-0327942GO:0015145
GeneOntologyMolecularFunctionbitter taste receptor activity

TAS2R9 TAS2R39

7.13e-0327942GO:0033038
GeneOntologyMolecularFunctionamino acid:monoatomic cation symporter activity

SLC6A8 SLC6A9

8.20e-0329942GO:0005416
GeneOntologyMolecularFunctionsugar transmembrane transporter activity

MFSD4B SLC2A11

8.20e-0329942GO:0051119
GeneOntologyMolecularFunctioninorganic anion transmembrane transporter activity

SLC37A1 SLC6A8 CLCA4 SLC4A4

8.71e-03171944GO:0015103
GeneOntologyMolecularFunctionmonoatomic ion-gated channel activity

TRPM5 TMEM63B

9.33e-0331942GO:0022839
GeneOntologyMolecularFunctionligand-gated calcium channel activity

TRPM5 TPCN1

9.33e-0331942GO:0099604
GeneOntologyMolecularFunctionsolute:inorganic anion antiporter activity

SLC37A1 SLC4A4

9.92e-0332942GO:0005452
GeneOntologyMolecularFunctionmodified amino acid transmembrane transporter activity

SLC6A8 SLC19A3

1.05e-0233942GO:0072349
GeneOntologyBiologicalProcessG protein-coupled receptor signaling pathway

OR10G6 OR51A4 OR51A2 TAS2R9 OR10A7 ADRA2A ADRA2B HTR2A GPR174 HTR2C OR4N5 OR4Q2 GPR153 SPNS2 ARHGEF1 GPR75 AGTR2 HCAR1 OR1D5 OR2V1 OR3A3 TAAR9 CCR7 CCR8 TAS2R39 OR56A1 OR2V2 GNRHR GPR119 OR4A4P CXCR2

4.08e-1413959431GO:0007186
GeneOntologyBiologicalProcessorganic cation transport

SLC6A9 ADRA2A ADRA2B HTR2C AGTR2 SLC19A3 SLC18B1 SLC7A10 SLC47A2 SLC16A10

1.18e-091459410GO:0015695
GeneOntologyBiologicalProcesssensory perception

OR10G6 OR51A4 OR51A2 TAS2R9 OR10A7 ADRA2A TMC1 HTR2A OR4N5 OR4Q2 SPNS2 PGAP1 ATP6V0A4 TMEM63B OR1D5 OR2V1 OR3A3 TAS2R39 OR56A1 OR2V2 OR4A4P SLC38A8

1.98e-0910729422GO:0007600
GeneOntologyBiologicalProcessdetection of stimulus involved in sensory perception

OR10G6 OR51A4 OR51A2 TAS2R9 OR10A7 TMC1 HTR2A OR4N5 OR4Q2 OR1D5 OR2V1 OR3A3 TAS2R39 OR56A1 OR2V2 OR4A4P

7.89e-095829416GO:0050906
GeneOntologyBiologicalProcessmonoatomic ion transport

SLC6A8 SLC6A9 SLC9A9 CLCA4 SLC22A25 ADRA2A TMC1 TRPM5 HTR2A HTR2C SLC16A1 SLC10A5 KCNV2 ATP6V0A4 TMEM63B CCR7 SLC4A4 MFSD4B SLC18B1 SLC47A2 CHRNB4 ATP6V0A2 TPCN1

3.68e-0813749423GO:0006811
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception

OR10G6 OR51A4 OR51A2 TAS2R9 OR10A7 OR4N5 OR4Q2 OR1D5 OR2V1 OR3A3 TAS2R39 OR56A1 OR2V2 OR4A4P

4.09e-084859414GO:0050907
GeneOntologyBiologicalProcessvascular process in circulatory system

SLC6A9 ADRA2A ADRA2B HTR2A HTR2C SLC16A1 SLC16A2 AGTR2 SLC28A2 SLC4A4 SLC29A1 CXCR2

5.36e-083449412GO:0003018
GeneOntologyBiologicalProcessorganic anion transport

SLC37A1 SLC6A8 SLC6A9 SLC22A25 HTR2C SLC16A1 SLC16A2 SLC10A5 AGTR2 SLC19A3 SLC4A4 SLC7A10 SLC38A8 SLC16A10

8.59e-085159414GO:0015711
GeneOntologyBiologicalProcessdetection of chemical stimulus

OR10G6 OR51A4 OR51A2 TAS2R9 OR10A7 OR4N5 OR4Q2 OR1D5 OR2V1 OR3A3 TAS2R39 OR56A1 OR2V2 OR4A4P

1.06e-075249414GO:0009593
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

SLC6A8 SLC6A9 SLC9A9 CLCA4 ADRA2A TMC1 TRPM5 HTR2A HTR2C SLC16A1 KCNV2 ATP6V0A4 TMEM63B CCR7 SLC4A4 SLC18B1 SLC47A2 CHRNB4 ATP6V0A2 TPCN1

1.13e-0711159420GO:0034220
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

SLC37A1 SLC6A8 SLC6A9 SLC9A9 CLCA4 ADRA2A TMC1 TRPM5 HTR2A HTR2C SLC16A1 KCNV2 ATP6V0A4 CCR7 SLC4A4 SLC18B1 SLC47A2 ATP6V0A2 TPCN1

1.33e-0710179419GO:0098660
GeneOntologyBiologicalProcessdetection of stimulus

OR10G6 OR51A4 OR51A2 TAS2R9 OR10A7 TMC1 HTR2A OR4N5 OR4Q2 OR1D5 OR2V1 OR3A3 TAS2R39 OR56A1 OR2V2 OR4A4P

1.55e-077229416GO:0051606
GeneOntologyBiologicalProcesssensory perception of chemical stimulus

OR10G6 OR51A4 OR51A2 TAS2R9 OR10A7 OR4N5 OR4Q2 OR1D5 OR2V1 OR3A3 TAS2R39 OR56A1 OR2V2 OR4A4P

1.79e-075479414GO:0007606
GeneOntologyBiologicalProcessmonoatomic cation transport

SLC6A8 SLC6A9 SLC9A9 ADRA2A TMC1 TRPM5 HTR2A HTR2C SLC16A1 SLC10A5 KCNV2 ATP6V0A4 TMEM63B CCR7 SLC4A4 MFSD4B SLC18B1 SLC47A2 ATP6V0A2 TPCN1

2.05e-0711579420GO:0006812
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

SLC6A8 SLC6A9 SLC9A9 ADRA2A TMC1 TRPM5 HTR2A HTR2C SLC16A1 KCNV2 ATP6V0A4 TMEM63B CCR7 SLC4A4 SLC18B1 SLC47A2 ATP6V0A2 TPCN1

2.15e-079429418GO:0098655
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception of smell

OR10G6 OR51A4 OR51A2 OR10A7 OR4N5 OR4Q2 OR1D5 OR2V1 OR3A3 OR56A1 OR2V2 OR4A4P

6.20e-074329412GO:0050911
GeneOntologyBiologicalProcessinorganic cation transmembrane transport

SLC6A8 SLC6A9 SLC9A9 ADRA2A TMC1 TRPM5 HTR2A HTR2C SLC16A1 KCNV2 ATP6V0A4 CCR7 SLC4A4 SLC18B1 SLC47A2 ATP6V0A2 TPCN1

8.06e-079229417GO:0098662
GeneOntologyBiologicalProcesssensory perception of smell

OR10G6 OR51A4 OR51A2 OR10A7 OR4N5 OR4Q2 OR1D5 OR2V1 OR3A3 OR56A1 OR2V2 OR4A4P

1.34e-064659412GO:0007608
GeneOntologyBiologicalProcesscarboxylic acid transport

SLC6A8 SLC6A9 HTR2C SLC16A1 SLC16A2 SLC10A5 AGTR2 SLC19A3 SLC7A10 SLC38A8 SLC16A10

2.63e-064109411GO:0046942
GeneOntologyBiologicalProcessorganic acid transport

SLC6A8 SLC6A9 HTR2C SLC16A1 SLC16A2 SLC10A5 AGTR2 SLC19A3 SLC7A10 SLC38A8 SLC16A10

2.76e-064129411GO:0015849
GeneOntologyBiologicalProcesstransport across blood-brain barrier

SLC6A9 SLC16A1 SLC16A2 SLC28A2 SLC4A4 SLC29A1

2.86e-0687946GO:0150104
GeneOntologyBiologicalProcessvascular transport

SLC6A9 SLC16A1 SLC16A2 SLC28A2 SLC4A4 SLC29A1

3.06e-0688946GO:0010232
GeneOntologyBiologicalProcessnegative regulation of norepinephrine secretion

ADRA2A ADRA2B AGTR2

1.47e-0511943GO:0010700
GeneOntologyBiologicalProcessregulation of synaptic transmission, glycinergic

SLC6A9 SLC7A10

2.05e-052942GO:0060092
GeneOntologyBiologicalProcessamino acid transport

SLC6A8 SLC6A9 HTR2C SLC16A2 SLC7A10 SLC38A8 SLC16A10

3.10e-05195947GO:0006865
GeneOntologyBiologicalProcesssodium ion transport

SLC6A8 SLC6A9 SLC9A9 TRPM5 SLC10A5 SLC4A4 MFSD4B TPCN1

3.73e-05275948GO:0006814
GeneOntologyBiologicalProcesssignal release

SLC6A9 ADRA2A ADRA2B HTR2A HTR2C SLC16A1 SLC16A2 AGTR2 GNRHR GPR119 CHRNB4 SLC16A10

4.09e-056539412GO:0023061
GeneOntologyBiologicalProcesspyrimidine-containing compound transmembrane transport

SLC19A3 SLC28A2 SLC29A1

4.92e-0516943GO:0072531
GeneOntologyBiologicalProcessexport from cell

SLC6A9 ADRA2A ADRA2B HTR2A HTR2C SLC16A1 SLC16A2 AGTR2 EQTN SLC4A4 GNRHR SLC47A2 SDC4 GPR119 CHRNB4 SLC16A10

6.08e-0511539416GO:0140352
GeneOntologyBiologicalProcessphospholipase C-activating serotonin receptor signaling pathway

HTR2A HTR2C

6.15e-053942GO:0007208
GeneOntologyBiologicalProcesspositive regulation of phosphatidylinositol biosynthetic process

HTR2A HTR2C

6.15e-053942GO:0010513
GeneOntologyBiologicalProcesssecretion

SLC6A9 ADRA2A ADRA2B HTR2A HTR2C SLC16A1 SLC16A2 AGTR2 EQTN TMEM63B SLC29A1 GNRHR SDC4 GPR119 CHRNB4 SLC16A10

1.19e-0412219416GO:0046903
GeneOntologyBiologicalProcessreceptor transactivation

ADRA2A ADRA2B

1.23e-044942GO:0035624
GeneOntologyBiologicalProcessinosine transport

SLC28A2 SLC29A1

1.23e-044942GO:0035340
GeneOntologyBiologicalProcesscirculatory system process

SLC6A9 ADRA2A ADRA2B HTR2A HTR2C SLC16A1 SLC16A2 AGTR2 SLC28A2 SLC4A4 SLC29A1 CXCR2

1.23e-047339412GO:0003013
GeneOntologyBiologicalProcessproton transmembrane transport

SLC9A9 SLC16A1 ATP6V0A4 SLC18B1 SLC47A2 ATP6V0A2

1.28e-04170946GO:1902600
GeneOntologyBiologicalProcessnegative regulation of catecholamine secretion

ADRA2A ADRA2B AGTR2

1.52e-0423943GO:0033604
GeneOntologyBiologicalProcessmetal ion transport

SLC6A8 SLC6A9 SLC9A9 ADRA2A TMC1 TRPM5 HTR2A HTR2C SLC10A5 KCNV2 CCR7 SLC4A4 MFSD4B TPCN1

1.69e-0410009414GO:0030001
GeneOntologyBiologicalProcessneurotransmitter transport

SLC6A8 SLC6A9 HTR2C SLC28A2 SLC18B1 SLC29A1 CHRNB4

1.83e-04259947GO:0006836
GeneOntologyBiologicalProcessmonoamine transport

ADRA2A ADRA2B HTR2A AGTR2 SLC18B1

1.90e-04116945GO:0015844
GeneOntologyBiologicalProcessthyroid-stimulating hormone secretion

SLC16A2 SLC16A10

2.04e-045942GO:0070460
GeneOntologyBiologicalProcessadenosine transport

SLC28A2 SLC29A1

2.04e-045942GO:0032238
GeneOntologyBiologicalProcesssynaptic transmission, glycinergic

SLC6A9 SLC7A10

2.04e-045942GO:0060012
GeneOntologyBiologicalProcessregulation of phosphatidylinositol biosynthetic process

HTR2A HTR2C

2.04e-045942GO:0010511
GeneOntologyBiologicalProcesssensitization

HTR2A HTR2C

2.04e-045942GO:0046960
GeneOntologyBiologicalProcesspurine nucleoside transmembrane transport

SLC28A2 SLC29A1

2.04e-045942GO:0015860
GeneOntologyBiologicalProcesscalcium-mediated signaling

TRPM5 HTR2C SPPL3 CCR7 CCR8 CXCR2 TPCN1

2.16e-04266947GO:0019722
GeneOntologyBiologicalProcessregulation of norepinephrine secretion

ADRA2A ADRA2B AGTR2

2.21e-0426943GO:0014061
GeneOntologyBiologicalProcessamino acid transmembrane transport

SLC6A9 SLC16A2 SLC7A10 SLC38A8 SLC16A10

2.23e-04120945GO:0003333
GeneOntologyBiologicalProcessorganic hydroxy compound transport

ADRA2A ADRA2B HTR2A SLC16A1 SLC10A5 AGTR2 SLC19A3 SLC18B1

2.32e-04358948GO:0015850
GeneOntologyBiologicalProcessregulation of catecholamine secretion

ADRA2A ADRA2B HTR2A AGTR2

2.49e-0467944GO:0050433
GeneOntologyBiologicalProcessregulation of amine transport

ADRA2A ADRA2B HTR2A HTR2C AGTR2

2.69e-04125945GO:0051952
GeneOntologyBiologicalProcessnorepinephrine secretion

ADRA2A ADRA2B AGTR2

2.76e-0428943GO:0048243
GeneOntologyBiologicalProcesspyrimidine nucleoside transport

SLC28A2 SLC29A1

3.05e-046942GO:0015864
GeneOntologyBiologicalProcessuridine transmembrane transport

SLC28A2 SLC29A1

3.05e-046942GO:0015862
GeneOntologyBiologicalProcesssecretion by cell

SLC6A9 ADRA2A ADRA2B HTR2A HTR2C SLC16A1 SLC16A2 AGTR2 EQTN GNRHR SDC4 GPR119 CHRNB4 SLC16A10

3.19e-0410649414GO:0032940
GeneOntologyBiologicalProcessphospholipase C-activating G protein-coupled receptor signaling pathway

ADRA2A HTR2A GPR174 HTR2C CXCR2

3.58e-04133945GO:0007200
GeneOntologyBiologicalProcesssodium ion transmembrane transport

SLC6A8 SLC6A9 SLC9A9 TRPM5 SLC4A4 TPCN1

3.81e-04208946GO:0035725
GeneOntologyBiologicalProcessamine transport

ADRA2A ADRA2B HTR2A HTR2C AGTR2

4.11e-04137945GO:0015837
GeneOntologyBiologicalProcesspositive regulation of neutrophil chemotaxis

PERP CCR7 CXCR2

4.13e-0432943GO:0090023
GeneOntologyBiologicalProcessmyoblast fusion involved in skeletal muscle regeneration

CD9 MYMK

4.25e-047942GO:0014905
GeneOntologyBiologicalProcesspyrimidine nucleobase transport

SLC28A2 SLC29A1

4.25e-047942GO:0015855
GeneOntologyBiologicalProcessmonocarboxylic acid transport

SLC6A8 SLC16A1 SLC16A2 SLC10A5 AGTR2 SLC16A10

4.32e-04213946GO:0015718
GeneOntologyBiologicalProcesscatecholamine secretion

ADRA2A ADRA2B HTR2A AGTR2

4.68e-0479944GO:0050432
GeneOntologyBiologicalProcessphenol-containing compound metabolic process

CYP2D7 HTR2C SLC16A2 AGTR2 SLC16A10

4.84e-04142945GO:0018958
GeneOntologyBiologicalProcessnucleoside transmembrane transport

SLC28A2 SLC29A1

5.65e-048942GO:1901642
GeneOntologyBiologicalProcesspurine nucleobase transmembrane transport

SLC28A2 SLC29A1

5.65e-048942GO:1904823
GeneOntologyBiologicalProcesspositive regulation of granulocyte chemotaxis

PERP CCR7 CXCR2

5.87e-0436943GO:0071624
GeneOntologyBiologicalProcessmembrane lipid metabolic process

TM9SF2 PLPP3 SPNS2 TECR PGAP1 CERS6

6.33e-04229946GO:0006643
GeneOntologyBiologicalProcessplasma membrane fusion

CD9 EQTN MYMK

6.37e-0437943GO:0045026
GeneOntologyBiologicalProcesshormone secretion

ADRA2A HTR2C SLC16A1 SLC16A2 AGTR2 GNRHR GPR119 SLC16A10

6.69e-04420948GO:0046879
GeneOntologyBiologicalProcessnorepinephrine transport

ADRA2A ADRA2B AGTR2

6.89e-0438943GO:0015874
GeneOntologyBiologicalProcesssensory perception of mechanical stimulus

TMC1 HTR2A SPNS2 PGAP1 ATP6V0A4 TMEM63B

7.74e-04238946GO:0050954
GeneOntologyBiologicalProcesshormone transport

ADRA2A HTR2C SLC16A1 SLC16A2 AGTR2 GNRHR GPR119 SLC16A10

8.03e-04432948GO:0009914
GeneOntologyBiologicalProcessregulation of neutrophil chemotaxis

PERP CCR7 CXCR2

8.62e-0441943GO:0090022
GeneOntologyBiologicalProcessregulation of intracellular pH

SLC9A9 ATP6V0A4 SLC4A4 ATP6V0A2

9.02e-0494944GO:0051453
GeneOntologyBiologicalProcessnegative regulation of epinephrine secretion

ADRA2A ADRA2B

9.03e-0410942GO:0032811
GeneOntologyBiologicalProcessnucleoside transport

SLC28A2 SLC29A1

9.03e-0410942GO:0015858
GeneOntologyBiologicalProcesscarboxylic acid transmembrane transport

SLC6A8 SLC6A9 SLC16A1 SLC7A10 SLC38A8

9.03e-04163945GO:1905039
GeneOntologyBiologicalProcessacute inflammatory response to antigenic stimulus

IL20RB CCR7 CXCR2

9.25e-0442943GO:0002438
GeneOntologyBiologicalProcesscatecholamine transport

ADRA2A ADRA2B HTR2A AGTR2

9.76e-0496944GO:0051937
GeneOntologyBiologicalProcessnegative regulation of amine transport

ADRA2A ADRA2B AGTR2

9.91e-0443943GO:0051953
GeneOntologyBiologicalProcessorganic acid transmembrane transport

SLC6A8 SLC6A9 SLC16A1 SLC7A10 SLC38A8

1.01e-03167945GO:1903825
GeneOntologyBiologicalProcesschemokine-mediated signaling pathway

GPR75 CCR7 CCR8 CXCR2

1.01e-0397944GO:0070098
GeneOntologyBiologicalProcessregulation of vasoconstriction

ADRA2A ADRA2B HTR2A HTR2C

1.05e-0398944GO:0019229
GeneOntologyBiologicalProcessserotonin receptor signaling pathway

HTR2A HTR2C

1.10e-0311942GO:0007210
GeneOntologyBiologicalProcessregulation of epinephrine secretion

ADRA2A ADRA2B

1.10e-0311942GO:0014060
GeneOntologyBiologicalProcessbehavioral response to nicotine

HTR2C CHRNB4

1.10e-0311942GO:0035095
GeneOntologyBiologicalProcessmyotube differentiation involved in skeletal muscle regeneration

CD9 MYMK

1.10e-0311942GO:0014908
GeneOntologyBiologicalProcessregulation of cellular pH

SLC9A9 ATP6V0A4 SLC4A4 ATP6V0A2

1.18e-03101944GO:0030641
GeneOntologyBiologicalProcesssphingolipid metabolic process

TM9SF2 PLPP3 SPNS2 TECR CERS6

1.27e-03176945GO:0006665
GeneOntologyBiologicalProcesspositive regulation of neutrophil migration

PERP CCR7 CXCR2

1.29e-0347943GO:1902624
GeneOntologyBiologicalProcessregulation of uterine smooth muscle contraction

ADRA2A ADRA2B

1.32e-0312942GO:0070472
GeneOntologyBiologicalProcesspurine nucleobase transport

SLC28A2 SLC29A1

1.32e-0312942GO:0006863
GeneOntologyBiologicalProcesspositive regulation of phospholipid biosynthetic process

HTR2A HTR2C

1.32e-0312942GO:0071073
GeneOntologyBiologicalProcessresponse to chemokine

GPR75 CCR7 CCR8 CXCR2

1.46e-03107944GO:1990868
GeneOntologyBiologicalProcesscellular response to chemokine

GPR75 CCR7 CCR8 CXCR2

1.46e-03107944GO:1990869
GeneOntologyBiologicalProcessL-amino acid transport

SLC6A9 SLC7A10 SLC38A8 SLC16A10

1.51e-03108944GO:0015807
GeneOntologyBiologicalProcessthyroid hormone transport

SLC16A2 SLC16A10

1.55e-0313942GO:0070327
GeneOntologyBiologicalProcessuterine smooth muscle contraction

ADRA2A ADRA2B

1.55e-0313942GO:0070471
GeneOntologyCellularComponentapical plasma membrane

SLC6A8 SLC6A9 CLCA4 CD9 SLC16A1 SLC16A2 ATP6V0A4 CLDND1 MFSD4B SLC29A1 SLC47A2

1.19e-054879411GO:0016324
GeneOntologyCellularComponentbasolateral plasma membrane

SLC6A9 SLC22A25 ADRA2A PLPP3 SLC16A1 ATP6V0A4 SLC4A4 SLC29A1 SLC16A10

1.40e-05320949GO:0016323
GeneOntologyCellularComponentbasal plasma membrane

SLC6A9 SLC22A25 ADRA2A PLPP3 SLC16A1 ATP6V0A4 SLC4A4 SLC29A1 SLC16A10

3.11e-05354949GO:0009925
GeneOntologyCellularComponentbasal part of cell

SLC6A9 SLC22A25 ADRA2A PLPP3 SLC16A1 ATP6V0A4 SLC4A4 SLC29A1 SLC16A10

5.17e-05378949GO:0045178
GeneOntologyCellularComponentapical part of cell

SLC6A8 SLC6A9 CLCA4 CD9 SLC16A1 SLC16A2 ATP6V0A4 CLDND1 MFSD4B SLC29A1 SLC47A2

7.05e-055929411GO:0045177
GeneOntologyCellularComponentvesicle membrane

SLC6A9 SLC9A9 TM9SF2 CD9 SPNS2 MARCHF3 MARCHF2 ATP6V0A4 EQTN SPPL3 SLC28A2 TMEM63B SLC18B1 CHRNB4 ATP6V0A2 CXCR2 TPCN1

7.78e-0513259417GO:0012506
GeneOntologyCellularComponentG protein-coupled serotonin receptor complex

HTR2A HTR2C

1.19e-044942GO:0098666
GeneOntologyCellularComponentcytoplasmic vesicle membrane

SLC6A9 SLC9A9 TM9SF2 CD9 SPNS2 MARCHF3 MARCHF2 ATP6V0A4 EQTN SPPL3 TMEM63B SLC18B1 CHRNB4 ATP6V0A2 CXCR2 TPCN1

2.23e-0413079416GO:0030659
GeneOntologyCellularComponentvacuolar proton-transporting V-type ATPase, V0 domain

ATP6V0A4 ATP6V0A2

8.79e-0410942GO:0000220
GeneOntologyCellularComponentproton-transporting V-type ATPase, V0 domain

ATP6V0A4 ATP6V0A2

1.28e-0312942GO:0033179
GeneOntologyCellularComponentendosome membrane

SLC9A9 TM9SF2 SPNS2 MARCHF3 MARCHF2 ATP6V0A4 TMEM63B ATP6V0A2 TPCN1

1.55e-03602949GO:0010008
HumanPhenoUnderfolded superior helices

SLC6A8 SLC16A2

2.51e-052262HP:0008583
DomainG_PROTEIN_RECEP_F1_2

OR10G6 OR51A4 OR51A2 TAS2R9 OR10A7 ADRA2A ADRA2B HTR2A GPR174 HTR2C OR4N5 GPR153 GPR75 AGTR2 HCAR1 OR1D5 OR2V1 OR3A3 TAAR9 CCR7 CCR8 OR56A1 OR2V2 GNRHR GPR119 CXCR2

1.16e-166919026PS50262
DomainGPCR_Rhodpsn

OR10G6 OR51A4 OR51A2 TAS2R9 OR10A7 ADRA2A ADRA2B HTR2A GPR174 HTR2C OR4N5 GPR153 GPR75 AGTR2 HCAR1 OR1D5 OR2V1 OR3A3 TAAR9 CCR7 CCR8 OR56A1 OR2V2 GNRHR GPR119 CXCR2

1.20e-166929026IPR000276
DomainGPCR_Rhodpsn_7TM

OR51A4 OR51A2 TAS2R9 OR10A7 ADRA2A ADRA2B HTR2A GPR174 HTR2C OR4N5 GPR153 GPR75 AGTR2 HCAR1 OR1D5 OR2V1 OR3A3 TAAR9 CCR7 CCR8 OR56A1 OR2V2 GNRHR GPR119 CXCR2

6.16e-166709025IPR017452
DomainG_PROTEIN_RECEP_F1_1

OR10G6 OR51A4 OR51A2 OR10A7 ADRA2A ADRA2B HTR2A GPR174 HTR2C OR4N5 GPR153 GPR75 AGTR2 HCAR1 OR1D5 OR2V1 OR3A3 TAAR9 CCR7 CCR8 OR56A1 OR2V2 GNRHR GPR119 CXCR2

1.03e-156859025PS00237
Domain7tm_1

OR10G6 OR51A4 OR51A2 OR10A7 ADRA2A ADRA2B HTR2A GPR174 HTR2C OR4N5 GPR153 GPR75 AGTR2 HCAR1 OR1D5 OR3A3 TAAR9 CCR7 CCR8 OR56A1 OR2V2 GNRHR GPR119 CXCR2

8.20e-156779024PF00001
DomainMFS_dom

SLC37A1 SLC22A25 MFSD14B SLC16A1 SLC16A2 SPNS2 SLC19A3 MFSD4B SLC18B1 SLC29A1 SLC2A11 SLC16A10

1.92e-121349012IPR020846
DomainMFS

SLC37A1 SLC22A25 MFSD14B SLC16A1 SLC16A2 SPNS2 MFSD4B SLC18B1 SLC16A10

1.15e-1077909IPR011701
DomainMFS_1

SLC37A1 SLC22A25 MFSD14B SLC16A1 SLC16A2 SPNS2 MFSD4B SLC18B1 SLC16A10

1.15e-1077909PF07690
DomainMFS

SLC37A1 SLC22A25 MFSD14B SLC16A1 SLC16A2 SPNS2 SLC18B1 SLC2A11 SLC16A10

2.47e-09108909PS50850
Domain7TM_GPCR_Srsx

OR51A4 OR51A2 ADRA2A ADRA2B HTR2A HTR2C TAAR9 OR56A1

6.69e-08112908SM01381
DomainOlfact_rcpt

OR10G6 OR51A4 OR51A2 OR10A7 OR4N5 OR1D5 OR2V1 OR3A3 OR56A1 OR2V2

1.94e-053939010IPR000725
DomainEMP70

TM9SF2 TM9SF3

1.37e-044902IPR004240
DomainV-type_ATPase_116kDa_su_euka

ATP6V0A4 ATP6V0A2

1.37e-044902IPR026028
DomainV_ATPase_I

ATP6V0A4 ATP6V0A2

1.37e-044902PF01496
DomainEMP70

TM9SF2 TM9SF3

1.37e-044902PF02990
DomainV-ATPase_116kDa_su

ATP6V0A4 ATP6V0A2

1.37e-044902IPR002490
DomainMARCH-like

MARCHF3 MARCHF2

6.31e-048902IPR033275
Domain5HT_rcpt

HTR2A HTR2C

8.09e-049902IPR002231
DomainADR_fam

ADRA2A ADRA2B

1.01e-0310902IPR002233
DomainRINGv

MARCHF3 MARCHF2

1.23e-0311902PF12906
DomainZF_RING_CH

MARCHF3 MARCHF2

1.23e-0311902PS51292
DomainChemokine_rcpt

CCR7 CCR8

2.64e-0316902IPR000355
DomainZnf_RING-CH

MARCHF3 MARCHF2

2.98e-0317902IPR011016
DomainRINGv

MARCHF3 MARCHF2

2.98e-0317902SM00744
DomainNA_NEUROTRAN_SYMP_2

SLC6A8 SLC6A9

3.34e-0318902PS00754
DomainNA_NEUROTRAN_SYMP_3

SLC6A8 SLC6A9

3.72e-0319902PS50267
DomainSNF

SLC6A8 SLC6A9

3.72e-0319902PF00209
DomainNa/ntran_symport

SLC6A8 SLC6A9

3.72e-0319902IPR000175
DomainNA_NEUROTRAN_SYMP_1

SLC6A8 SLC6A9

3.72e-0319902PS00610
DomainSUGAR_TRANSPORT_1

MFSD14B SLC2A11

5.92e-0324902PS00216
DomainTAS2R

TAS2R9 TAS2R39

6.92e-0326902PF05296
DomainT2R

TAS2R9 TAS2R39

6.92e-0326902IPR007960
DomainSugar_transporter_CS

MFSD14B SLC2A11

1.04e-0232902IPR005829
PathwayWP_GPCRS_CLASS_A_RHODOPSINLIKE

ADRA2A ADRA2B HTR2A GPR174 HTR2C GPR75 AGTR2 HCAR1 OR1D5 OR3A3 CCR7 CCR8 CXCR2

1.15e-092607613M39397
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC6A9 SLC9A9 SLC16A1 SLC16A2 SLC28A2 SLC4A4 MFSD4B SLC7A10 SLC29A1 SLC47A2 SLC2A11 SLC16A10

8.07e-092497612M5988
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

SLC6A9 SLC9A9 CLCA4 TRPM5 SLC16A1 SLC16A2 ATP6V0A4 SLC28A2 SLC4A4 MFSD4B SLC7A10 SLC29A1 ABCA9 SLC47A2 SLC2A11 ATP6V0A2 TPCN1 SLC16A10

4.86e-087367618M27287
PathwayREACTOME_GPCR_LIGAND_BINDING

TAS2R9 ADRA2A ADRA2B HTR2A HTR2C AGTR2 HCAR1 PTCH2 TAAR9 CCR7 CCR8 TAS2R39 GNRHR CXCR2

1.49e-074637614M507
PathwayREACTOME_SENSORY_PERCEPTION

OR10G6 OR51A4 OR51A2 OR10A7 TMC1 TRPM5 OR4N5 OR4Q2 OR1D5 OR2V1 OR3A3 TAS2R39 OR56A1 OR2V2 SDC4

1.22e-066367615M41834
PathwayREACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS

ADRA2A ADRA2B HTR2A HTR2C AGTR2 HCAR1 TAAR9 CCR7 CCR8 GNRHR CXCR2

1.44e-063307611M18334
PathwayWP_GPCRS_NONODORANT

ADRA2A ADRA2B GPR174 HTR2C AGTR2 CCR7 CCR8 GNRHR GPR119 CXCR2

1.54e-062667610MM15843
PathwayREACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS

ADRA2A ADRA2B HTR2A HTR2C AGTR2 HCAR1 TAAR9 CCR7 CCR8 GNRHR CXCR2

1.58e-063337611MM14963
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

SLC6A9 SLC9A9 CLCA4 TRPM5 SLC16A1 SLC16A2 ATP6V0A4 SLC28A2 SLC4A4 SLC7A10 SLC29A1 ABCA9 ATP6V0A2 TPCN1 SLC16A10

2.84e-066817615MM14985
PathwayREACTOME_AMINE_LIGAND_BINDING_RECEPTORS

ADRA2A ADRA2B HTR2A HTR2C TAAR9

2.90e-0642765M5868
PathwayREACTOME_AMINE_LIGAND_BINDING_RECEPTORS

ADRA2A ADRA2B HTR2A HTR2C TAAR9

2.90e-0642765MM14971
PathwayREACTOME_GPCR_LIGAND_BINDING

ADRA2A ADRA2B HTR2A HTR2C AGTR2 HCAR1 TAAR9 CCR7 CCR8 TAS2R39 GNRHR CXCR2

2.95e-064307612MM15160
PathwayREACTOME_SIGNALING_BY_GPCR

TAS2R9 ADRA2A ADRA2B HTR2A HTR2C ARHGEF1 AGTR2 HCAR1 PTCH2 TAAR9 CCR7 CCR8 TAS2R39 GNRHR CXCR2

4.12e-067027615M746
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC6A9 SLC9A9 SLC16A1 SLC16A2 SLC28A2 SLC4A4 SLC7A10 SLC29A1 SLC16A10

5.10e-06238769MM15076
PathwayREACTOME_OLFACTORY_SIGNALING_PATHWAY

OR10G6 OR51A4 OR51A2 OR10A7 OR4N5 OR4Q2 OR1D5 OR2V1 OR3A3 OR56A1 OR2V2

1.35e-054177611M4072
PathwayWP_MONOAMINE_GPCRS

ADRA2A ADRA2B HTR2A HTR2C

2.83e-0533764M39585
PathwayWP_GPCRS_PEPTIDE

AGTR2 CCR7 CCR8 GNRHR CXCR2

3.67e-0570765MM15959
PathwayREACTOME_SIGNALING_BY_GPCR

ADRA2A ADRA2B HTR2A HTR2C ARHGEF1 AGTR2 HCAR1 TAAR9 CCR7 CCR8 TAS2R39 GNRHR CXCR2

3.70e-056467613MM14962
PathwayREACTOME_G_ALPHA_I_SIGNALLING_EVENTS

TAS2R9 ADRA2A ADRA2B AGTR2 HCAR1 CCR7 CCR8 TAS2R39 CXCR2

4.63e-05314769M600
PathwayWP_PEPTIDE_GPCRS

AGTR2 CCR7 CCR8 GNRHR CXCR2

5.13e-0575765M39696
PathwayKEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION

ADRA2A ADRA2B HTR2A HTR2C AGTR2 TAAR9 GNRHR CHRNB4

1.05e-04272768M13380
PathwayREACTOME_G_ALPHA_I_SIGNALLING_EVENTS

ADRA2A ADRA2B AGTR2 HCAR1 CCR7 CCR8 TAS2R39 CXCR2

1.60e-04289768MM15057
PathwayKEGG_OLFACTORY_TRANSDUCTION

OR51A4 OR51A2 CLCA4 OR10A7 OR4N5 OR1D5 OR3A3 OR56A1 OR2V2

2.35e-04389769M14091
PathwayWP_PROXIMAL_TUBULE_TRANSPORT

ATP6V0A4 SLC4A4 SLC47A2 SLC16A10

2.48e-0457764M39812
PathwayWP_GPCRS_CLASS_A_RHODOPSINLIKE

ADRA2A ADRA2B HTR2C AGTR2 CCR8 CXCR2

4.95e-04186766MM15994
PathwayWP_MONOAMINE_GPCRS

ADRA2A ADRA2B HTR2C

6.07e-0431763MM15871
PathwayREACTOME_ADRENOCEPTORS

ADRA2A ADRA2B

1.01e-039762M27302
PathwayKEGG_MEDICUS_REFERENCE_THYROID_HORMONE_SIGNALING_PATHWAY

SLC16A2 SLC16A10

1.01e-039762M47629
PathwayREACTOME_ADRENOCEPTORS

ADRA2A ADRA2B

1.01e-039762MM15009
PathwayREACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES

SLC16A2 SLC28A2 SLC29A1

1.39e-0341763MM15075
PathwayREACTOME_TRANSPORT_OF_NUCLEOSIDES_AND_FREE_PURINE_AND_PYRIMIDINE_BASES_ACROSS_THE_PLASMA_MEMBRANE

SLC28A2 SLC29A1

1.53e-0311762MM15471
PathwayREACTOME_SEROTONIN_RECEPTORS

HTR2A HTR2C

1.53e-0311762MM15008
PathwayREACTOME_RIBAVIRIN_ADME

SLC28A2 SLC29A1

1.53e-0311762M46429
PathwayWP_GPCRS_ODORANT

GPR153 GPR75 HCAR1 TAAR9 TAS2R39

1.57e-03157765MM15872
PathwayWP_GPCRS_OTHER

HTR2A OR3A3 GNRHR CXCR2

1.58e-0393764M39629
PathwayREACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES

SLC16A2 SLC28A2 SLC29A1

1.59e-0343763M881
PathwayREACTOME_TRANSPORT_OF_NUCLEOSIDES_AND_FREE_PURINE_AND_PYRIMIDINE_BASES_ACROSS_THE_PLASMA_MEMBRANE

SLC28A2 SLC29A1

1.83e-0312762M27728
PathwayREACTOME_RIBAVIRIN_ADME

SLC28A2 SLC29A1

1.83e-0312762MM16638
PathwayREACTOME_SEROTONIN_RECEPTORS

HTR2A HTR2C

1.83e-0312762M6034
PathwayWP_LACTATE_SHUTTLE_IN_GLIAL_CELLS

SLC16A1 SLC4A4

2.15e-0313762M48056
PathwayWP_SEROTONIN_AND_ANXIETYRELATED_EVENTS

HTR2A HTR2C

2.50e-0314762M39614
PathwayREACTOME_ION_CHANNEL_TRANSPORT

CLCA4 TRPM5 ATP6V0A4 ATP6V0A2 TPCN1

2.59e-03176765MM15718
PathwayREACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES

SLC9A9 SLC4A4 SLC7A10 SLC16A10

2.74e-03108764M823
PathwayKEGG_TASTE_TRANSDUCTION

TAS2R9 TRPM5 TAS2R39

2.75e-0352763M5785
PathwayREACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES

SLC9A9 SLC4A4 SLC7A10 SLC16A10

2.83e-03109764MM15074
PathwayREACTOME_ION_CHANNEL_TRANSPORT

CLCA4 TRPM5 ATP6V0A4 ATP6V0A2 TPCN1

3.06e-03183765M997
PathwayWP_MAJOR_RECEPTORS_TARGETED_BY_EPINEPHRINE_AND_NOREPINEPHRINE

ADRA2A ADRA2B

3.28e-0316762M39849
PathwayREACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES

CCR7 CCR8 CXCR2

3.58e-0357763M625
PathwayWP_SEROTONIN_AND_ANXIETY

HTR2A HTR2C

3.70e-0317762M39511
PathwayREACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES

CCR7 CCR8 CXCR2

3.76e-0358763MM14978
PathwayREACTOME_DRUG_ADME

CYP2D7 SLC16A1 SLC28A2 SLC29A1

3.88e-03119764MM15692
PathwayWP_SEROTONIN_RECEPTOR_2_AND_ELKSRFGATA4_SIGNALING

HTR2A HTR2C

5.12e-0320762M39485
PathwayREACTOME_CELLULAR_HEXOSE_TRANSPORT

MFSD4B SLC2A11

5.64e-0321762M27058
Pubmed

Reviews in molecular biology and biotechnology: transmembrane signaling by G protein-coupled receptors.

ADRA2A ADRA2B HTR2A HTR2C AGTR2 TAAR9 CCR7 CCR8 GNRHR CXCR2

1.88e-10200941018240029
Pubmed

Systematic protein-protein interaction mapping for clinically relevant human GPCRs.

SLC37A1 SLC6A8 SLC9A9 CLCA4 HTR2C TM9SF2 SLC16A1 CLDND1 CCR8 CERS6 SLC18B1 SLC29A1 GNRHR ATP6V0A2

5.90e-09697941428298427
Pubmed

Establishment and Dysfunction of the Blood-Brain Barrier.

SLC6A9 SLC16A1 SLC16A2 SLC28A2 SLC29A1

3.04e-075294526590417
Pubmed

Blood-Brain Barrier: From Physiology to Disease and Back.

SLC6A9 SLC16A1 SLC16A2 SLC28A2 SLC4A4 SLC29A1

4.30e-0710594630280653
Pubmed

A study of candidate genotypes associated with dyspepsia in a U.S. community.

ADRA2A HTR2A HTR2C

6.64e-07794316464220
Pubmed

Support for association between ADHD and two candidate genes: NET1 and DRD1.

ADRA2A HTR2A HTR2C

3.11e-061194315717291
Pubmed

The SLC16 gene family-from monocarboxylate transporters (MCTs) to aromatic amino acid transporters and beyond.

SLC16A1 SLC16A2 SLC16A10

6.81e-061494312739169
Pubmed

Depression in Alzheimer's disease: the effect of serotonin receptor gene variation.

HTR2A HTR2C

7.23e-06294212707936
Pubmed

The thyroid hormone transporters MCT8 and MCT10 transport the affinity-label N-bromoacetyl-[(125)I]T3 but are not modified by it.

SLC16A2 SLC16A10

7.23e-06294221315799
Pubmed

Unified approach to the analysis of genetic variation in serotonergic pathways.

HTR2A HTR2C

7.23e-06294210581480
Pubmed

5HT2A and 5HT2C receptor polymorphisms and predicting clinical response to olanzapine in schizophrenia.

HTR2A HTR2C

7.23e-06294212454564
Pubmed

Candidate gene associations with withdrawn behavior.

ADRA2A HTR2A

7.23e-06294223808549
Pubmed

Regulation of serotonin-2C receptor G-protein coupling by RNA editing.

HTR2A HTR2C

7.23e-0629429153397
Pubmed

Activation of alpha 2B-adrenoceptors mediates the cardiovascular effects of etomidate.

ADRA2A ADRA2B

7.23e-06294214508322
Pubmed

Contribution of 5-HT2A receptor gene -1438A>G polymorphism to outcome of attention-deficit/hyperactivity disorder in adolescents.

HTR2A HTR2C

7.23e-06294216741915
Pubmed

Association of 5-HTR2A and 5-HTR2C serotonin receptor gene polymorphisms with depression risk in patients with coronary heart disease.

HTR2A HTR2C

7.23e-06294224770757
Pubmed

Pharmacological and behavioral characterization of the 5-HT2A receptor in C57BL/6N mice.

HTR2A HTR2C

7.23e-06294221340474
Pubmed

Effective cellular uptake and efflux of thyroid hormone by human monocarboxylate transporter 10.

SLC16A2 SLC16A10

7.23e-06294218337592
Pubmed

Association studies of 5-HT2A and 5-HT2C serotonin receptor gene polymorphisms with prophylactic lithium response in bipolar patients.

HTR2A HTR2C

7.23e-06294216382194
Pubmed

Cloning of the human serotonin 5-HT2 and 5-HT1C receptor subtypes.

HTR2A HTR2C

7.23e-0629421722404
Pubmed

Deafness and loss of cochlear hair cells in the absence of thyroid hormone transporters Slc16a2 (Mct8) and Slc16a10 (Mct10).

SLC16A2 SLC16A10

7.23e-06294229535325
Pubmed

The Differential Effect of a Shortage of Thyroid Hormone Compared with Knockout of Thyroid Hormone Transporters Mct8 and Mct10 on Murine Macrophage Polarization.

SLC16A2 SLC16A10

7.23e-06294238396788
Pubmed

Advanced glycation end products elicit externalization of phosphatidylserine in a subpopulation of platelets via 5-HT2A/2C receptors.

HTR2A HTR2C

7.23e-06294217625040
Pubmed

Role of 5HT 2A and 5HT 2C polymorphisms in behavioural and psychological symptoms of Alzheimer's disease.

HTR2A HTR2C

7.23e-06294217098333
Pubmed

Quantitative changes in intracellular calcium and extracellular-regulated kinase activation measured in parallel in CHO cells stably expressing serotonin (5-HT) 5-HT2A or 5-HT2C receptors.

HTR2A HTR2C

7.23e-06294222397586
Pubmed

MARCH-III Is a novel component of endosomes with properties similar to those of MARCH-II.

MARCHF3 MARCHF2

7.23e-06294216428329
Pubmed

[The association between polymorphism of the serotonin 2A, 2C receptor genes and obstructive sleep apnea-hypopnea syndrome in Han population].

HTR2A HTR2C

7.23e-06294218336767
Pubmed

Novel pyrimidoazepine analogs as serotonin 5-HT(2A) and 5-HT(2C) receptor ligands for the treatment of obesity.

HTR2A HTR2C

7.23e-06294223537943
Pubmed

The membrane-associated ubiquitin ligases MARCH2 and MARCH3 target IL-5 receptor alpha to negatively regulate eosinophilic airway inflammation.

MARCHF3 MARCHF2

7.23e-06294235982175
Pubmed

Developmental enhancement of alpha2-adrenoceptor-mediated suppression of inhibitory synaptic transmission onto mouse cerebellar Purkinje cells.

ADRA2A ADRA2B

7.23e-06294218691636
Pubmed

Association between HTR2C and HTR2A polymorphisms and metabolic abnormalities in patients treated with olanzapine or clozapine.

HTR2A HTR2C

7.23e-06294219142110
Pubmed

5-HT(2A) and 5-HT(2C) receptors exert opposing effects on locomotor activity in mice.

HTR2A HTR2C

7.23e-06294219322172
Pubmed

Tissue-specific alterations in thyroid hormone homeostasis in combined Mct10 and Mct8 deficiency.

SLC16A2 SLC16A10

7.23e-06294224248460
Pubmed

Serotonin-2A and 2C receptor gene polymorphisms in Japanese patients with obstructive sleep apnea.

HTR2A HTR2C

7.23e-06294216258205
Pubmed

Expression of thyroid hormone transporters in the human placenta and changes associated with intrauterine growth restriction.

SLC16A2 SLC16A10

7.23e-06294220167367
Pubmed

Association of Serotonin Receptor Gene Polymorphisms with Regulatory and Adaptive Capacities of Medical Students.

HTR2A HTR2C

7.23e-06294237768455
Pubmed

5-HT(2A) and 5-HT(2C) receptor stimulation are differentially involved in the cortical dopamine efflux-Studied in 5-HT(2A) and 5-HT(2C) genetic mutant mice.

HTR2A HTR2C

7.23e-06294221118683
Pubmed

5-HT2A and 5-HT2C serotonin receptors differentially modulate mouse sexual arousal and the hypothalamo-pituitary-testicular response to the presence of a female.

HTR2A HTR2C

7.23e-06294212097814
Pubmed

Structural basis of PDZ-mediated chemokine receptor CXCR2 scaffolding by guanine nucleotide exchange factor PDZ-RhoGEF.

ARHGEF1 CXCR2

7.23e-06294228179147
Pubmed

Chronic lithium administration to rats selectively modifies 5-HT2A/2C receptor-mediated brain signaling via arachidonic acid.

HTR2A HTR2C

7.23e-06294215562295
Pubmed

Effects of thyroid hormone transporters MCT8 and MCT10 on nuclear activity of T3.

SLC16A2 SLC16A10

7.23e-06294227492966
Pubmed

Expression of chemokine receptors CCR7 and CCR8 in the CNS during ChREAE.

CCR7 CCR8

7.23e-06294217850582
Pubmed

Ligand recognition of serine-cysteine amino acid exchanges in transmembrane domain 5 of alpha2-adrenergic receptors by UK 14,304.

ADRA2A ADRA2B

7.23e-06294210737629
Pubmed

Sound-induced seizures in serotonin 5-HT2c receptor mutant mice.

HTR2A HTR2C

7.23e-0629429241279
Pubmed

Serotonin 5-HT2a and 5-HT2c receptors stimulate amyloid precursor protein ectodomain secretion.

HTR2A HTR2C

7.23e-0629428626761
Pubmed

Dissociation of heterotrimeric g proteins in cells.

ADRA2A HTR2A AGTR2 CCR7 CCR8 CXCR2

9.56e-0617994618577758
Pubmed

The human olfactory receptor gene family.

OR10G6 OR10A7 OR4N5 OR4Q2 OR1D5 OR3A3 OR56A1 OR2V2 OR4A4P

1.64e-0554194914983052
Pubmed

A multivariate analysis of 59 candidate genes in personality traits: the temperament and character inventory.

ADRA2A ADRA2B HTR2A HTR2C

1.90e-055894411140838
Pubmed

Positive association between panic disorder and polymorphism of the serotonin 2A receptor gene.

HTR2A HTR2C

2.16e-05394212759158
Pubmed

Polymorphisms of the 5-hydroxytryptamine 2A/2C receptor genes and 5-hydroxytryptamine transporter gene in Chinese patients with OSAHS.

HTR2A HTR2C

2.16e-05394223494654
Pubmed

The Thyroid Hormone Transporter MCT10 Is a Novel Regulator of Trabecular Bone Mass and Bone Turnover in Male Mice.

SLC16A2 SLC16A10

2.16e-05394234669927
Pubmed

Heterodimers of serotonin receptor subtypes 2 are driven by 5-HT2C protomers.

HTR2A HTR2C

2.16e-05394228258217
Pubmed

Single Nucleotide Polymorphisms in Thyroid Hormone Transporter Genes MCT8, MCT10 and Deiodinase DIO2 Contribute to Inter-Individual Variance of Executive Functions and Personality Traits.

SLC16A2 SLC16A10

2.16e-05394231820424
Pubmed

Rab26 modulates the cell surface transport of α2-adrenergic receptors from the Golgi.

ADRA2A ADRA2B

2.16e-05394223105096
Pubmed

Tardive dyskinesia and DRD3, HTR2A and HTR2C gene polymorphisms in Russian psychiatric inpatients from Siberia.

HTR2A HTR2C

2.16e-05394219439249
Pubmed

Association of the serotonin transporter and receptor gene polymorphisms in neuropsychiatric symptoms in Alzheimer disease.

HTR2A HTR2C

2.16e-05394215313842
Pubmed

Effect on diurnal intraocular pressure variation of eliminating the alpha-2 adrenergic receptor subtypes in the mouse.

ADRA2A ADRA2B

2.16e-05394218326714
Pubmed

Pharmacological characterization of mitogen-activated protein kinase activation by recombinant human 5-HT2C, 5-HT2A, and 5-HT2B receptors.

HTR2A HTR2C

2.16e-05394219057895
Pubmed

Monocarboxylate transporters in cancer.

SLC16A1 HCAR1

2.16e-05394231395464
Pubmed

Serotonin and the 5-HT(2B) receptor in the development of enteric neurons.

HTR2A HTR2C

2.16e-05394210627607
Pubmed

Serotonergic pathway genes and subtypes of alcoholism: association studies.

HTR2A HTR2C

2.16e-05394211525423
Pubmed

Delayed transactivation of the receptor for nerve growth factor is required for sustained signaling and differentiation by alpha2-adrenergic receptors in transfected PC12 cells.

ADRA2A ADRA2B

2.16e-05394217215105
Pubmed

Distribution of mRNA encoding three alpha 2-adrenergic receptor subtypes in the developing mouse embryo suggests a role for the alpha 2A subtype in apoptosis.

ADRA2A ADRA2B

2.16e-0539429415717
Pubmed

Seasonal affective disorder and serotonin-related polymorphisms.

HTR2A HTR2C

2.16e-05394211300730
Pubmed

Agonist-directed trafficking of signalling at serotonin 5-HT2A, 5-HT2B and 5-HT2C-VSV receptors mediated Gq/11 activation and calcium mobilisation in CHO cells.

HTR2A HTR2C

2.16e-05394218703043
Pubmed

Expression of alpha 2-adrenergic receptor subtypes in the mouse brain: evaluation of spatial and temporal information imparted by 3 kb of 5' regulatory sequence for the alpha 2A AR-receptor gene in transgenic animals.

ADRA2A ADRA2B

2.16e-0539428843087
Pubmed

Direct inhibition of cardiac hyperpolarization-activated cyclic nucleotide-gated pacemaker channels by clonidine.

ADRA2A ADRA2B

2.16e-05394217261653
Pubmed

Monocarboxylate transporter 10 functions as a thyroid hormone transporter in chondrocytes.

SLC16A2 SLC16A10

2.16e-05394222719050
Pubmed

Expression of 5-HT(2A), 5-HT(2B) and 5-HT(2C) receptors in the mouse embryo.

HTR2A HTR2C

2.16e-05394210978843
Pubmed

Hippocampal transcriptional and neurogenic changes evoked by combination yohimbine and imipramine treatment.

ADRA2A HTR2C

2.16e-05394225784603
Pubmed

Alpha2-adrenoceptor subtypes involved in the regulation of catecholamine release from the adrenal medulla of mice.

ADRA2A ADRA2B

2.16e-05394217075569
Pubmed

Opposing effects of α2- and β-adrenergic receptor stimulation on quiescent neural precursor cell activity and adult hippocampal neurogenesis.

ADRA2A ADRA2B

2.16e-05394224922313
Pubmed

Molecular determinants for the interaction of the valvulopathic anorexigen norfenfluramine with the 5-HT2B receptor.

HTR2A HTR2C

2.16e-05394215831837
Pubmed

Deletion of Eqtn in mice reduces male fertility and sperm-egg adhesion.

CD9 EQTN

2.16e-05394230328350
Pubmed

Unaltered lactate and glucose transporter levels in the MPTP mouse model of Parkinson's disease.

SLC16A1 SLC16A2

2.16e-05394223963315
Pubmed

Haplotype-based analysis of alpha 2A, 2B, and 2C adrenergic receptor genes captures information on common functional loci at each gene.

ADRA2A ADRA2B

2.16e-05394215592690
Pubmed

The role of dopamine D3, 5-HT2A and 5-HT2C receptor variants as pharmacogenetic determinants in tardive dyskinesia in African-Caribbean patients under chronic antipsychotic treatment: Curacao extrapyramidal syndromes study IX.

HTR2A HTR2C

2.16e-05394218562401
Pubmed

Abnormal regulation of the sympathetic nervous system in alpha2A-adrenergic receptor knockout mice.

ADRA2A ADRA2B

2.16e-05394210385696
Pubmed

Platelet Serotonin (5-HT) Concentration, Platelet Monoamine Oxidase B (MAO-B) Activity and HTR2A, HTR2C, and MAOB Gene Polymorphisms in Asthma.

HTR2A HTR2C

2.16e-05394237238670
Pubmed

Association between common genetic variants of α2A-, α2B-, and α2C-adrenergic receptors and ischemic stroke.

ADRA2A ADRA2B

2.16e-05394222560155
Pubmed

Regulation of alpha(2)-adrenoceptors in human vascular smooth muscle cells.

ADRA2A ADRA2B

2.16e-05394212946937
Pubmed

Two functionally distinct alpha2-adrenergic receptors regulate sympathetic neurotransmission.

ADRA2A ADRA2B

2.16e-05394210647009
Pubmed

Characterization of chemokine receptors expressed in primitive blood cells during human hematopoietic ontogeny.

CCR8 CXCR2

2.16e-05394211007922
Pubmed

The pharmacology and distribution of human 5-hydroxytryptamine2B (5-HT2B) receptor gene products: comparison with 5-HT2A and 5-HT2C receptors.

HTR2A HTR2C

2.16e-0539427582481
Pubmed

Resting sympathetic nerve activity is related to age, sex and arterial pressure but not to α2-adrenergic receptor subtype.

ADRA2A ADRA2B

2.16e-05394220613626
Pubmed

Nefopam but not physostigmine affects the thermoregulatory response in mice via alpha(2)-adrenoceptors.

ADRA2A ADRA2B

2.16e-05394219744502
Pubmed

Lack of association between three serotonin genes and suicidal behavior in Chinese psychiatric patients.

HTR2A HTR2C

2.16e-05394217964050
Pubmed

Alpha2-adrenoceptors modulating neuronal serotonin release: a study in alpha2-adrenoceptor subtype-deficient mice.

ADRA2A ADRA2B

2.16e-05394211181434
Pubmed

Function of brain α2B-adrenergic receptor characterized with subtype-selective α2B antagonist and KO mice.

ADRA2A ADRA2B

2.16e-05394227751959
Pubmed

The Thyroid Hormone Transporter Mct8 Restricts Cathepsin-Mediated Thyroglobulin Processing in Male Mice through Thyroid Auto-Regulatory Mechanisms That Encompass Autophagy.

SLC16A2 SLC16A10

2.16e-05394233466458
Pubmed

Mixture regression analysis on age at onset in bipolar disorder patients: investigation of the role of serotonergic genes.

HTR2A HTR2C

2.16e-05394220452754
Pubmed

Insertion/insertion genotype of α(2B)-adrenergic receptor gene polymorphism is associated with silent myocardial ischemia in patients with type 2 diabetes mellitus.

ADRA2A ADRA2B

2.16e-05394220692245
Pubmed

5-HT2 receptors facilitate JC polyomavirus entry.

HTR2A HTR2C

2.16e-05394224089568
Pubmed

Targeting adrenergic receptors to mitigate invariant natural killer T cells-induced acute liver injury.

ADRA2A ADRA2B

2.16e-05394237841583
Pubmed

Two alpha(2)-adrenergic receptor subtypes, alpha(2A) and alpha(2C), inhibit transmitter release in the brain of gene-targeted mice.

ADRA2A ADRA2B

2.16e-05394211927164
Pubmed

Serotonergic candidate genes and puerperal psychosis: an association study.

HTR2A HTR2C

2.16e-05394217728663
Pubmed

Association between Common Genetic Variants of α2A-, α2B-, and α2C-Adrenergic Receptors and Orthostatic Hypotension.

ADRA2A ADRA2B

2.16e-05394226427149
Pubmed

Brain region-specific alterations of 5-HT2A and 5-HT2C receptors in serotonin transporter knockout mice.

HTR2A HTR2C

2.16e-05394212614326
Pubmed

Antinociceptive action of nitrous oxide is mediated by stimulation of noradrenergic neurons in the brainstem and activation of [alpha]2B adrenoceptors.

ADRA2A ADRA2B

2.16e-05394211125002
Pubmed

Differential control of adrenal and sympathetic catecholamine release by alpha 2-adrenoceptor subtypes.

ADRA2A ADRA2B

2.16e-05394212764077
GeneFamilySolute carriers

SLC37A1 SLC6A8 SLC6A9 SLC9A9 SLC22A25 SLC16A1 SLC16A2 SLC10A5 SLC19A3 SLC28A2 SLC4A4 SLC18B1 SLC7A10 SLC29A1 SLC47A2 SLC2A11 SLC38A8 SLC16A10

1.60e-143957318752
GeneFamilyTransmembrane 9 superfamily members

TM9SF2 TM9SF3

9.60e-0547321239
GeneFamilyG protein-coupled receptors, Class A orphans

GPR174 GPR153 GPR75 GPR119

2.78e-0478734262
GeneFamilyAdrenoceptors

ADRA2A ADRA2B

5.68e-049732169
GeneFamilyCD molecules|C-C motif chemokine receptors

CCR7 CCR8

7.09e-04107321091
GeneFamilyRing finger proteins|Membrane associated ring-CH-type fingers

MARCHF3 MARCHF2

8.64e-041173260
GeneFamily5-hydroxytryptamine receptors, G protein-coupled

HTR2A HTR2C

1.22e-0313732170
GeneFamilyV-type ATPases

ATP6V0A4 ATP6V0A2

3.85e-0323732415
GeneFamilyTaste 2 receptors

TAS2R9 TAS2R39

1.08e-02397321162
GeneFamilyCD molecules|I-set domain containing|Immunoglobulin like domain containing|Interleukin receptors|TIR domain containing

IL20RB CXCR2

1.25e-0242732602
GeneFamilyOlfactory receptors, family 51

OR51A4 OR51A2

1.36e-0244732164
GeneFamilyOlfactory receptors, family 4

OR4N5 OR4Q2 OR4A4P

1.54e-02129733151
GeneFamilyX-linked mental retardation|Angiotensin receptors

SLC16A2 AGTR2

1.94e-0253732103
CoexpressionKONDO_PROSTATE_CANCER_WITH_H3K27ME3

KIRREL3 SLC22A25 OR10A7 CLDND1 VWA2 ABCA9 SIAH3

5.23e-06194917M7281
ToppCellE17.5-Epithelial|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CD9 DRAM1 ATP6V0A4 PERP TMEM63B SDC4

2.69e-06187936fdabe716ce67f2eede90548198cbe20bbf693570
ToppCellNS-moderate-d_07-13|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CLCA4 CD9 PERP CCR7 SDC4 SLC16A10

3.42e-06195936088209505a68519ec89f50f0576096da6966bf17
ToppCellTracheal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Duct|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CD9 SPNS2 ATP6V0A4 PERP SLC4A4 SDC4

3.84e-06199936527aae1d9d37a50deefc01fc0c064a53673681bd
ToppCellPosterior_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Synpr-Inhibitory_Neuron.Gad1Gad2.Synpr-Sncg_(Neuron.Gad1Gad2.Synpr-Sncg)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

TMC1 MARCHF3 AGTR2 MYMK

1.76e-0574934216721986c3055f2d9b4702be9693b3a0892283c
ToppCellPosterior_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Synpr-Inhibitory_Neuron.Gad1Gad2.Synpr-Sncg_(Neuron.Gad1Gad2.Synpr-Sncg)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

TMC1 MARCHF3 AGTR2 MYMK

1.76e-0574934a7f7ed7316c226e18ee62d0149be7404326817c6
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-Tregs|GI_small-bowel / Manually curated celltypes from each tissue

CCR7 CCR8 OR2V2 SLC7A10 SLC16A10

1.97e-05157935c44bd530e396b08f16f284e185dcb830843959ea
ToppCellPND07-28-samps-Myeloid-Macrophage-macrophage-B|PND07-28-samps / Age Group, Lineage, Cell class and subclass

HTR2C CD9 DDHD1 PERP GALNT6

2.16e-05160935694bf1f1952bd8ab444819f533da24fa2b73f701
ToppCellfacs-Thymus-Flowthrough-24m-Epithelial|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD9 PLPP3 TMEM212 SLC19A3 CXCR2

2.29e-05162935ebce09d96e02820ce7d33ad3f417586f96efed76
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A8 TRPM5 CCR7 SDC4 SIAH3

2.29e-0516293522f1abd20f43bc7e7fc46969da9962faf70ae5d2
ToppCellfacs-Thymus-Flowthrough-24m-Epithelial-TECs|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD9 PLPP3 TMEM212 SLC19A3 CXCR2

2.29e-0516293596c8ed9d9cb1cf4175c2f41a6e4ebe02a378044c
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A8 TRPM5 CCR7 SDC4 SIAH3

2.29e-05162935966df4558140c3d541999ab553f201ae76a1c401
ToppCellfacs-Thymus-Flowthrough-24m-Epithelial-epithelial_cell_of_thymus|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD9 PLPP3 TMEM212 SLC19A3 CXCR2

2.29e-05162935b4adb9c053e02e71b0f1a6e7ab6dddc34a7245e0
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Macroglial-astrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MARCHF3 SLC4A4 MFSD4B SLC7A10 SDC4

2.65e-051679352184c2760b6142e62124a2454a552723e20d4f61
ToppCellPND03-Immune-Immune_Myeloid-Granulocytic-Basophil|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GPR174 GPR75 PERP GALNT6 CXCR2

3.14e-051739358ca650542655c27516029e5bace97ff1b9dcc256
ToppCellPND03-Immune-Immune_Myeloid-Granulocytic-Basophil-Basophil_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GPR174 GPR75 PERP GALNT6 CXCR2

3.14e-051739354282b47b33325472f52a4085986988911a372ed8
ToppCellLPS-antiTNF-Lymphocytic_NKT-T_cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GPR174 MARCHF3 ARHGEF1 CCR7 CERS6

3.40e-05176935ea27e18407b8a13e8212830da859efeb8f158690
ToppCellLPS-antiTNF-Lymphocytic_NKT-T_cells-T-cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GPR174 MARCHF3 ARHGEF1 CCR7 CERS6

3.40e-05176935bfbab3c5b738b3b0b1540f2059d0245fbd8c0031
ToppCelldroplet-Spleen-nan-24m-Hematologic-erythroblast|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A9 SLC16A1 MARCHF3 MARCHF2 SLC16A10

3.59e-051789359c4950357087212b2388116ba8866c359628694d
ToppCelldroplet-Marrow-nan-24m-Myeloid-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A9 SLC16A1 MARCHF3 MARCHF2 SLC16A10

3.69e-051799357e6da098976c7801d31dcc0201f813d2bc8b07fc
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DRAM1 PERP IL20RB VWA2 SDC4

3.89e-05181935a5e770b5b5d57cbac18560828e89f7c96b687743
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DRAM1 PERP IL20RB VWA2 SDC4

3.89e-05181935504b1af1951a7a20ef5db69d84c20630ec64095b
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Epithelial-neuroepithelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DRAM1 PERP IL20RB VWA2 SDC4

3.89e-05181935a55ec36d2393f7a376feb42b22aee75dfdf4c383
ToppCelldroplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_PP_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD9 HCAR1 SDC4 GPR119 SLC16A10

3.99e-051829355b2bad38c723cd64a7fe7f2dcd361708014c8cfe
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia/MHC-D|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CD9 SLC16A1 TECR TMEM212 RELL1

4.10e-051839358c63f751cfa5b7455cd075a72387eab64f5a66e0
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Epithelial-Bergmann_glial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLPP3 GPR153 PTCH2 SLC4A4 SDC4

4.21e-05184935f6148e9591e8845cc62668e49fd52755257cdc7e
ToppCell10x5'v1-week_17-19-Hematopoietic-erythroid-mid_erythroid|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

SLC6A8 SLC6A9 MARCHF3 MARCHF2 TMEM63B

4.32e-05185935e9059cefcdf0972ec90793b1dd34c3292b17a061
ToppCellfacs-Lung-ENDOMUCIN-18m-Lymphocytic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR174 ARHGEF1 SLC28A2 CCR7 GALNT6

4.43e-051869356e3bea4319d2a1bb060fe0cb1bb8bafafa05f83c
ToppCellE17.5-Epithelial-alveolar_epithelial_cell|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CD9 DRAM1 ATP6V0A4 TMEM63B SDC4

4.43e-05186935a7a2ef8392a045a62fa4d0983577711d5d397dc4
ToppCelldroplet-Bladder-BLADDER-1m-Epithelial-bladder_urothelial_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PGAP1 PERP TMEM63B GALNT6 SDC4

4.54e-05187935aa336fb568a24e12c0454265ddd71ed10a6614cf
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD4+_T-Treg-Treg_1|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SLC16A1 DDHD1 CLDND1 CCR8 SLC16A10

4.54e-051879359fdfca5b70f585843ef9d810154674a8e561e765
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PERP IL20RB VWA2 SLC29A1 SDC4

4.78e-051899356f0fc5271a7d3682f145e734abc3be6473dda2e2
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PERP IL20RB VWA2 SLC29A1 SDC4

4.78e-051899353b9ce8964b16cb2200d30cbb0bfc711dcad2380e
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Epithelial-neuroepithelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PERP IL20RB VWA2 SLC29A1 SDC4

4.78e-0518993538acb307907fde68b992057714448c1561d69ee3
ToppCellE17.5-Epithelial-epithelial_progenitor_cell-epithelial_progenitor_cell|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CD9 DRAM1 ATP6V0A4 PERP SDC4

4.90e-051909358e9ba1f1af520564a1a7dfa9ef74ef5f0d0bf0d5
ToppCellE18.5-samps-Epithelial|E18.5-samps / Age Group, Lineage, Cell class and subclass

CD9 DRAM1 ATP6V0A4 TMEM63B SDC4

4.90e-0519093590accc078e9a72329a415d5cefe062c4196bb624
ToppCellfacs-MAT-Fat-3m-Lymphocytic-nan|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR174 ARHGEF1 CCR7 CCR8 GALNT6

5.02e-05191935530469909ab0994bece37945e9098359077b0824
ToppCellE18.5-samps-Epithelial-Alveolar_epithelial|E18.5-samps / Age Group, Lineage, Cell class and subclass

CD9 DRAM1 ATP6V0A4 TMEM63B SDC4

5.02e-051919351cd4d513ac363fdda07030b85a88174d29af3588
ToppCellfacs-MAT-Fat-3m-Lymphocytic|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR174 ARHGEF1 CCR7 CCR8 GALNT6

5.02e-05191935f7a81acb938ce5d383326840dd45f7dd2cf12b1d
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_ALM_Nxph2_Sla|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

KCNV2 PTCH2 CCR7 RELL1

5.12e-05979340d68bf2dfb9c221375b70b055f735536afb18f65
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia/MHC-A|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CD9 PLPP3 SLC16A1 SPNS2 SDC4

5.15e-051929352dee0402e97e48157e0bc01bcc8034f1645dfb7b
ToppCellCD8+_Memory_T_cell-RSV-5|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

CD9 SLC16A1 CCR7 CCR8 CERS6

5.15e-051929356357af0fb60a13a0ac727bc922b7606ab520ef5c
ToppCellE16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-Sox9_Epi-Sox9_Epi_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CD9 DRAM1 ATP6V0A4 PERP SDC4

5.28e-0519393533c495a2a7252b48ce10321642fd675d03cc80fc
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW19-OPC_related|GW19 / Sample Type, Dataset, Time_group, and Cell type.

SLC6A9 SLC9A9 HTR2C GALNT6 SLC7A10

5.28e-0519393580ae4d11e373e54ead919294786e0a8cbd11ea8a
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW19-OPC_related-OPC|GW19 / Sample Type, Dataset, Time_group, and Cell type.

SLC6A9 SLC9A9 HTR2C GALNT6 SLC7A10

5.28e-051939355c3b4cc1ca8439ac59ba00253903b9774dc048f8
ToppCellBL-critical-LOC-Epithelial-Basal|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CLCA4 SLC16A2 PERP IL20RB SLC4A4

5.41e-051949352932f704656ca368565ec12f3452af3b18e8df12
ToppCellLA-14._Fibroblast_III|World / Chamber and Cluster_Paper

SLC9A9 DRAM1 MARCHF3 PGAP1 ABCA9

5.41e-05194935803fa83ceada17c38ca9f933b888f7e7b0b90761
ToppCellPND01-Epithelial|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CD9 DRAM1 ATP6V0A4 TMEM63B SDC4

5.41e-05194935d21db5e942966ed44bc78ff50130a201fc627074
ToppCellE16.5-Epithelial|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CD9 DRAM1 TECR PERP SDC4

5.54e-05195935e2d9856e4bd6259f0988cfefd7ce364f15681bf8
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)-Goblet_(subsegmental)_L.0.4.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADRA2A TM9SF3 HCAR1 GALNT6 SLC4A4

5.54e-051959352a9a36df1dbc4eac77a8ddbe939ec8a8d6c41464
ToppCellPND01-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CD9 DRAM1 ATP6V0A4 TMEM63B SDC4

5.54e-0519593543164511f32e4591cb5399182fbac0b911716233
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADRA2A TM9SF3 HCAR1 GALNT6 SLC4A4

5.54e-05195935576142b4e75457c0973051bccc4163bd624496af
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADRA2A TM9SF3 HCAR1 GALNT6 SLC4A4

5.54e-051959358f151066ad3ebd9661ea0b733f03c2ce1518f9ad
ToppCellPND01-Epithelial-Epithelial_Alveolar|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CD9 DRAM1 ATP6V0A4 TMEM63B SDC4

5.54e-051959359337111d75a487abc02969337718c30b1fe81379
ToppCell10x3'2.3-week_14-16-Hematopoietic-erythroid-mid_erythroid|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

SLC6A8 SLC6A9 MARCHF3 MARCHF2 TMEM63B

5.54e-051959354759018a7c016cb2e3df5696f1e5f912c7c9ee17
ToppCell3'-Child04-06-SmallIntestine-Epithelial-epithelial_progenitor_cell-Stem_cells|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CD9 PGAP1 PERP CERS6 SDC4

5.54e-05195935b67d4f34cae729c18275486d3b20c9dd7d5cbe79
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-club_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADRA2A CD9 HCAR1 SLC4A4 SDC4

5.68e-051969351b3a191749cf143d35f7f73cf0e239535ece0ca7
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADRA2A CD9 HCAR1 SLC4A4 SDC4

5.68e-0519693550436ddc61e4ab8df055a527e7514aaaaf6e90ee
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW23-Macroglial-Astrocyte|GW23 / Sample Type, Dataset, Time_group, and Cell type.

SPINK13 SLC6A9 CD9 PLPP3 SLC7A10

5.68e-0519693555a10faafcbe075eefdfcd7cff25ded040c23538
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW23-Macroglial|GW23 / Sample Type, Dataset, Time_group, and Cell type.

SPINK13 SLC6A9 CD9 PLPP3 SLC7A10

5.68e-051969358025ec8aee8455c7b0261aa4a0caacebd2f50634
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADRA2A CD9 HCAR1 SLC4A4 SDC4

5.68e-051969350d83501e580de523aac073709395ed7b889e0bb2
ToppCellTransverse-T_cell-Treg|T_cell / Region, Cell class and subclass

SLC9A9 MARCHF3 CCR7 CCR8 SLC16A10

5.82e-05197935b7a1637e4baadd657f6279f4aa96cd590c9cd8c9
ToppCelldistal-1-Epithelial-Basal|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SLC6A8 CLCA4 HTR2C PERP IL20RB

5.82e-0519793525a2ccc98b973611de0d920b1b455d0b40f0d37f
ToppCelldistal-Epithelial-Basal-1|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SLC6A8 CLCA4 HTR2C PERP IL20RB

5.82e-0519793575b4292ce2ad7f9c8b6a4781e1cb71f5b18b74e3
ToppCell3'-Child04-06-SmallIntestine-Epithelial-epithelial_progenitor_cell-TA|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CD9 PGAP1 PERP CERS6 SDC4

5.96e-05198935a4543d636501a1b5b46c14a661ce9d169947c82c
ToppCell3'-Child04-06-SmallIntestine-Epithelial-epithelial_progenitor_cell|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CD9 PGAP1 PERP CERS6 SDC4

5.96e-05198935e8bfae3888b2406b5629b576cb02913b3297337e
ToppCell3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.2.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SLC6A8 CLCA4 CD9 PERP IL20RB

5.96e-0519893522935a8afac54021f68b5f7a5accf51523e2f336
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-AC-like-AC-like-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SLC6A9 CD9 PLPP3 GPR75 SLC18B1

6.10e-05199935a900ef002e1ae583b70be0253d8c44dae6754916
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CLCA4 CD9 TM9SF3 PERP IL20RB

6.10e-05199935fbd39d34636137d1b877dd8815d58f124990136b
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CLCA4 CD9 TM9SF3 PERP IL20RB

6.10e-051999356977f939ddbc47d4921f36c0a61a205259fe1284
ToppCelldroplet-Trachea-3m-Mesenchymal-fibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CD9 SLC16A2 ATP6V0A4 SLC29A1 SDC4

6.25e-05200935be527df943a8cedc6452ecef3cafc282db34ceb8
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Mesenchymal-Mesoderm|10w / Sample Type, Dataset, Time_group, and Cell type.

SLC28A2 PERP PTCH2 RELL1 SDC4

6.25e-052009359ef226ebb0a7cdb9431e2fa65faa2a7d67da590d
ToppCellNasal_Brush-Epithelial|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

CD9 TECR TM9SF3 PERP SDC4

6.25e-052009357911073119ee47a37b68b73fc54f063e902a5067
ToppCelldroplet-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l28|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CD9 SLC16A2 ATP6V0A4 SLC29A1 SDC4

6.25e-05200935d254f6634895486f81d7a8b6f006fbc2679eaa5b
ToppCelldroplet-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CD9 SLC16A2 ATP6V0A4 SLC29A1 SDC4

6.25e-052009358e41a484038216f0c2ad258fd46c0e702a4bb8bf
ToppCellParenchyma_COVID-19-Epithelial-TX-Club|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

ADRA2A HCAR1 PERP GALNT6 SLC4A4

6.25e-0520093585f946dd3831acf3488c87efba96689cc2667c3a
ToppCelldroplet-Trachea-nan-3m-Mesenchymal-fibroblast|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD9 SLC16A2 ATP6V0A4 SLC29A1 SDC4

6.25e-05200935c935caef2988f165e96d8f1ef99ae8963ab9377f
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-Club-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ADRA2A HCAR1 PERP GALNT6 SLC4A4

6.25e-052009358a44a4f7ea9358f2194a490e79601c98ff7fdcb0
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-Club|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

ADRA2A HCAR1 PERP GALNT6 SLC4A4

6.25e-0520093530d428510c68da96c7c8cfd472f449ebb9631132
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Satb1_(Substantia_Innominata_(SI))|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

SPINK13 KCNV2 ATP6V0A4

9.26e-0542933f4ce47a88935f1eaa9395791294ae567aac92545
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Satb1_(Substantia_Innominata_(SI))-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

SPINK13 KCNV2 ATP6V0A4

9.26e-054293314eda1c244cf32cade59fd2f57dd9bc00c97c895
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Satb1_(Substantia_Innominata_(SI))--|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

SPINK13 KCNV2 ATP6V0A4

9.26e-0542933f02985b8cdbd858c362766953a8f08ce338e8ce7
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sncg-Sncg_Vip_Nptx2|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

KIRREL3 HTR2C MARCHF3 MYMK

1.25e-0412293491e338db581b36baffecc323b1909f2069b27242
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Ductal_and_Metaplastic_Carcinoma-4|TCGA-Breast / Sample_Type by Project: Shred V9

CLCA4 TMC1 HTR2C CHRNB4

1.29e-0412393411802979943a9205f10facda322fc220d4bf7133
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Ductal_and_Metaplastic_Carcinoma|TCGA-Breast / Sample_Type by Project: Shred V9

CLCA4 TMC1 HTR2C CHRNB4

1.29e-0412393451e49a64fbbf77e2ee21f45fd515d43282b11516
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-Tfh|GI_small-bowel / Manually curated celltypes from each tissue

ATP6V0A4 CCR7 CCR8 SLC16A10

1.41e-04126934d0d3e25e4fb074a76313fc90d8c3828b1d8ea486
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Cdkn1c_(Cdkn1c)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

SPINK13 IL20RB CXCR2

2.43e-045893317a83e082c819692eaf4f49981f1127dd98e0a0c
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Cdkn1c_(Cdkn1c)-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

SPINK13 IL20RB CXCR2

2.43e-0458933630c9cfbaabacd99f4519f1f960fb59ca3b6fe9c
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Cdkn1c_(Cdkn1c)--|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

SPINK13 IL20RB CXCR2

2.43e-045893344ac4a3e212fb202a066a913d9116f50fe255f6e
ToppCellLPS-IL1RA+antiTNF-Hematopoietic_Mast-Mast_cells|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GPR174 TMEM212 GALNT6 SLC38A8

2.48e-04146934a5c84ad44d6ffb25028a4fd5454fd5de81b16a5e
ToppCellLPS-IL1RA+antiTNF-Hematopoietic_Mast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GPR174 TMEM212 GALNT6 SLC38A8

2.48e-041469348133037881c15e75637fc616091a7055488dd5fc
ToppCelldroplet-Pancreas-Exocrine-18m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DRAM1 SLC10A5 TMEM212 GALNT6

2.68e-04149934defe2e4a2f3118f8b42e99a4f2bf03e54c1b698f
ToppCellEnthrocyte|World / shred on cell class and cell subclass (v4)

SLC16A1 MARCHF3 MARCHF2 SLC16A10

2.97e-04153934654265f3c14344071b2af7ca05cbdbb17ce2c5d3
ToppCellEnthrocyte|World / shred on cell class and cell subclass (v4)

SLC16A1 MARCHF3 MARCHF2 SLC16A10

2.97e-04153934105b91f5277d145f7717307d7eb9b7d8e8e23576
ToppCell3'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SLC16A2 HCAR1 PTCH2 SLC4A4

2.97e-0415393492a5307b8e4dcf9ee42134b4c0645f9d488df61a
ToppCellfacs-Large_Intestine-Distal-3m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AMBN TRPM5 HTR2A AGTR2

2.97e-041539343b1b0cc8e9dd2b1484649789330713282ee44414
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-myeloid-myeloid_macrophage-Langerhans_cell|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SLC16A2 CCR7 CERS6 SLC16A10

3.04e-04154934617ad0929d2ac0eeb7b8d9b0cba687176e684ed0
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW23-Neuronal-Interneuron|GW23 / Sample Type, Dataset, Time_group, and Cell type.

AMBN MFSD4B SIAH3

3.10e-0463933c10d344bf32a091deb79e1f128f7dd5e9f4abaa3
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC37A1 TRPM5 TMEM212 VWA2

3.12e-04155934441fcb6d05364fc6f4973f0b973f1a80b573ce1f
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-IPC_like|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

SLC16A2 SLC10A5 PGAP1 CHRNB4

3.19e-041569347e6805ebc7bc2f9c5965321d16922c155719970f
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-IPC_like-IPs_and_early_cortical_neurons|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

SLC16A2 SLC10A5 PGAP1 CHRNB4

3.19e-04156934741de05295b2d012ac8576378f37709a97c8fb50
ComputationalGenes in the cancer module 146.

ADRA2A ADRA2B HTR2C GPR75 CCR8 CHRNB4

1.86e-06102406MODULE_146
ComputationalGenes in the cancer module 288.

AGTR2 CCR8 GNRHR CXCR2

9.94e-0637404MODULE_288
ComputationalMembranal receptors.

ADRA2A ADRA2B HTR2A CD9 SLC16A2 CCR8 SLC4A4 CHRNB4

5.34e-04517408MODULE_64
DrugNRA 0045

ADRA2A ADRA2B HTR2A HTR2C

1.58e-088904ctd:C106996
DrugS 15931

ADRA2A ADRA2B HTR2A HTR2C

2.83e-089904CID000182596
DrugS 14671

ADRA2A ADRA2B HTR2A HTR2C

4.71e-0810904CID000131907
DrugYohimbine

ADRA2A ADRA2B HTR2A HTR2C

4.71e-0810904DB01392
DrugMOLI001424

ADRA2A ADRA2B HTR2A CD9

1.59e-0713904CID009552075
Drugtransdihydrolisuride

ADRA2A ADRA2B HTR2A HTR2C TECR

2.19e-0734905CID000005406
DrugLisuride

ADRA2A ADRA2B HTR2A HTR2C

2.22e-0714904DB00589
DrugPramipexole

ADRA2A ADRA2B HTR2A HTR2C

2.22e-0714904DB00413
DrugRopinirole

ADRA2A ADRA2B HTR2A HTR2C

2.22e-0714904DB00268
DrugRisperidone

ADRA2A ADRA2B HTR2A HTR2C

2.22e-0714904DB00734
DrugCabergoline

ADRA2A ADRA2B HTR2A HTR2C

3.01e-0715904DB00248
DrugApomorphine

ADRA2A ADRA2B HTR2A HTR2C

3.01e-0715904DB00714
Drugnorfenfluramine

ADRA2A ADRA2B HTR2A HTR2C PLPP3

3.40e-0737905CID000015897
DrugAC1LD8XI

ADRA2A ADRA2B HTR2A HTR2C

4.01e-0716904CID000644287
DrugPaliperidone

ADRA2A ADRA2B HTR2A HTR2C

5.22e-0717904DB01267
DrugPergolide

ADRA2A ADRA2B HTR2A HTR2C

5.22e-0717904DB01186
DrugS 15535

ADRA2A ADRA2B HTR2A HTR2C

5.22e-0717904CID000132787
DrugSaphris

ADRA2A ADRA2B HTR2A HTR2C TECR

5.78e-0741905CID000163091
DrugBromocriptine

ADRA2A ADRA2B HTR2A HTR2C

6.70e-0718904DB01200
DrugMethotrimeprazine

ADRA2A ADRA2B HTR2A HTR2C

8.46e-0719904DB01403
DrugICI 169,369

ADRA2A ADRA2B HTR2A HTR2C

1.05e-0620904CID000122265
DrugDoxepin

ADRA2A ADRA2B HTR2A HTR2C

1.05e-0620904DB01142
DrugMirtazapine

ADRA2A HTR2A HTR2C

1.18e-066903DB00370
DrugMianserin

ADRA2A HTR2A HTR2C

1.18e-066903DB06148
Drug7-hydroxychlorpromazine

ADRA2A ADRA2B CYP2D7

1.18e-066903CID000016414
Drugsertindole

ADRA2A ADRA2B HTR2A CYP2D7 HTR2C

1.59e-0650905CID000060149
Drugtrazodone

ADRA2A ADRA2B HTR2A CYP2D7 HTR2C

1.76e-0651905CID000005533
DrugLurasidone Hydrochloride

ADRA2A HTR2A HTR2C

2.07e-067903ctd:D000069056
DrugTrazodone

ADRA2A HTR2A HTR2C

2.07e-067903DB00656
Drugperphenazine

ADRA2A ADRA2B HTR2A CYP2D7 HTR2C

2.13e-0653905CID000004748
Drugmirtazapine

ADRA2A ADRA2B HTR2A CYP2D7 HTR2C

2.34e-0654905CID000004205
DrugOlanzapine

ADRA2A ADRA2B HTR2A HTR2C

2.71e-0625904DB00334
DrugZiprasidone

ADRA2A ADRA2B HTR2A HTR2C

2.71e-0625904DB00246
DrugAripiprazole

ADRA2A ADRA2B HTR2A HTR2C

2.71e-0625904DB01238
Drugquetiapine

ADRA2A ADRA2B HTR2A CYP2D7 HTR2C

3.07e-0657905CID000005002
DrugClozapine

ADRA2A ADRA2B HTR2A HTR2C

3.19e-0626904DB00363
DrugQuetiapine

ADRA2A ADRA2B HTR2A HTR2C

3.19e-0626904DB01224
DrugT15550

ADRA2A ADRA2B HTR2A HTR2C

3.19e-0626904CID000005454
DrugS 14489

ADRA2A ADRA2B HTR2A

3.30e-068903CID000182595
DrugNSC169490

ADRA2A ADRA2B HTR2A HTR2C

3.74e-0627904CID004210613
DrugPCMBS

SLC37A1 SLC16A1 SLC16A2 SLC28A2 SLC29A1 SLC2A11

3.79e-06105906CID000011136
Drugsodium

SLC6A9 SLC9A9 TRPM5 SLC16A1 SLC16A2 TECR ATP6V0A4 AGTR2 SLC28A2 SLC4A4 SLC7A10 SLC29A1 SLC2A11 TPCN1 SLC16A10

4.11e-069449015CID000000923
DrugL-741,626

ADRA2A ADRA2B HTR2A HTR2C

4.35e-0628904CID000133633
Drugroxindole

ADRA2A ADRA2B HTR2A HTR2C

4.35e-0628904CID000219050
Drugetilevodopa

ADRA2A ADRA2B HTR2A

4.93e-069903CID000170345
DrugNefazodone

ADRA2A HTR2A HTR2C

4.93e-069903DB01149
Drugpindolol

ADRA2A ADRA2B HTR2A CYP2D7 HTR2C

5.06e-0663905CID000004828
DrugAC1L1G8Z

ADRA2A ADRA2B HTR2A HTR2C

5.78e-0630904CID000003581
DrugS-(-)-Lisuride

ADRA2A ADRA2B HTR2A HTR2C TECR

5.91e-0665905CID000003938
DrugErgotamine

ADRA2A ADRA2B HTR2A

7.03e-0610903DB00696
DrugMDMA

ADRA2A ADRA2B HTR2A CYP2D7 HTR2C TPCN1

8.60e-06121906CID000001615
Drugfluspirilene

ADRA2A ADRA2B HTR2A HTR2C

9.67e-0634904CID000003396
Drugphendioxan

ADRA2A ADRA2B HTR2A HTR2C

1.09e-0535904CID000185453
Drugpimozide

ADRA2A ADRA2B HTR2A HTR2C GNRHR TPCN1

1.14e-05127906CID000016362
Drugmolindone

ADRA2A ADRA2B HTR2A HTR2C

1.22e-0536904CID000023897
DrugAC1MHW5N

ADRA2A ADRA2B HTR2A CD9

1.22e-0536904CID003058747
Drugiloperidone

ADRA2A ADRA2B HTR2A HTR2C

1.22e-0536904CID000071360
Drugaripiprazole

ADRA2A ADRA2B HTR2A CYP2D7 HTR2C

1.28e-0576905CID000060795
Drugpipamperone

ADRA2A ADRA2B HTR2A HTR2C

1.52e-0538904CID000004830
Drugthioridazine

ADRA2A ADRA2B HTR2A CYP2D7 HTR2C

1.54e-0579905CID000005452
DrugNapamezol

ADRA2A ADRA2B

1.55e-052902CID000124655
DrugWy 27127

ADRA2A ADRA2B

1.55e-052902CID000125697
Drugdomperidone

ADRA2A ADRA2B HTR2A HTR2C GNRHR

1.64e-0580905CID000003151
DrugRX821002

ADRA2A ADRA2B HTR2A HTR2C

1.87e-0540904CID000108094
DrugNSC95090

ADRA2A ADRA2B HTR2A HTR2C

1.87e-0540904CID000003251
DrugCabergoline-d5

ADRA2A ADRA2B HTR2A HTR2C KCNV2

1.96e-0583905CID000002512
DrugBMY 7378

ADRA2A ADRA2B HTR2A HTR2C

2.07e-0541904CID000002419
DrugYM348

ADRA2A HTR2A HTR2C

2.11e-0514903CID003045225
Drugfipamezole

ADRA2A ADRA2B HTR2A

2.11e-0514903CID000213041
Drugspiroxatrine

ADRA2A ADRA2B HTR2A HTR2C

2.28e-0542904CID000005268
Drugmianserin

ADRA2A ADRA2B HTR2A CYP2D7 HTR2C

2.47e-0587905CID000004184
Drugthiethylperazine

HTR2A CYP2D7 HTR2C

2.63e-0515903CID000005440
Drugidazoxan

ADRA2A ADRA2B HTR2A HTR2C ATP6V0A2

2.76e-0589905CID000054459
Drugpiperazine dihydrochloride

HTR2A HTR2C TECR

3.22e-0516903CID000008893
Drugloxapine

ADRA2A ADRA2B HTR2A HTR2C

3.28e-0546904CID000003964
DrugAC-680

ADRA2A ADRA2B HTR2A CYP2D7 HTR2C

3.41e-0593905CID000004691
DrugNAN-190

ADRA2A ADRA2B HTR2A HTR2C

3.58e-0547904CID000004431
Drugfluphenazine

ADRA2A ADRA2B HTR2A CYP2D7 HTR2C

3.59e-0594905CID000003372
DrugErgot

ADRA2A ADRA2B HTR2A HTR2C

3.89e-0548904CID000003250
DrugWAY-100635

ADRA2A ADRA2B HTR2A HTR2C

4.22e-0549904CID000005684
DrugNSC150531

ADRA2A ADRA2B HTR2A CYP2D7

4.22e-0549904CID000004475
Drugzotepine

ADRA2A ADRA2B HTR2A HTR2C

4.22e-0549904CID000005736
DrugAC1Q7BEJ

ADRA2A ADRA2B HTR2A HTR2C

4.58e-0550904CID000001224
DrugClonidine

ADRA2A ADRA2B

4.62e-053902DB00575
DrugBrimonidine

ADRA2A ADRA2B

4.62e-053902DB00484
DrugCGS 19281A

ADRA2A ADRA2B

4.62e-053902CID000169339
Drug6-methoxymianserin

HTR2A HTR2C

4.62e-053902ctd:C461657
DrugICI 106270

ADRA2A ADRA2B

4.62e-053902CID000128761
Drug1,3,4,14b-tetrahydro-2,10-dimethyl-2H,10H-pyrazino(2,1-d)pyrrolo(1,2-b) (1,2,5)benzotriazepine

HTR2A HTR2C

4.62e-053902ctd:C507420
Druggamma-mangostin

HTR2A HTR2C

4.62e-053902ctd:C102777
DrugMe-M

HTR2A HTR2C

4.62e-053902CID000077590
DrugNorfenfluramine

HTR2A HTR2C

4.62e-053902ctd:D009642
DrugTizanidine

ADRA2A ADRA2B

4.62e-053902DB00697
DrugM100907

ADRA2A ADRA2B HTR2A HTR2C

4.95e-0551904CID000060858
Drugchloride

SLC6A9 SLC9A9 CLCA4 ADRA2A ADRA2B HTR2A HTR2C SLC16A1 TECR ATP6V0A4 SLC4A4 SLC7A10 SLC29A1 SLC16A10

4.97e-0510299014CID000000312
DrugGBR 12935

ADRA2A ADRA2B HTR2A

6.49e-0520903CID000003456
Drug6-fluoronorepinephrine

ADRA2A ADRA2B HTR2A

7.54e-0521903CID000001862
Drugfenfluramine

ADRA2A ADRA2B HTR2A CYP2D7 HTR2C PLPP3

7.59e-05178906CID000003337
DrugMHPG

ADRA2A ADRA2B HTR2C PERP

7.68e-0557904CID000010805
Drugnorclozapine

ADRA2A ADRA2B HTR2A HTR2C

7.68e-0557904CID000002820
Diseaserenal tubular acidosis (implicated_via_orthology)

ATP6V0A4 SLC4A4 ATP6V0A2

1.28e-068853DOID:14219 (implicated_via_orthology)
Diseaserenal tubular acidosis (is_implicated_in)

ATP6V0A4 SLC4A4

4.90e-054852DOID:14219 (is_implicated_in)
Diseaseautosomal recessive osteopetrosis 1 (implicated_via_orthology)

ATP6V0A4 ATP6V0A2

8.15e-055852DOID:0110942 (implicated_via_orthology)
DiseaseDistal Renal Tubular Acidosis

ATP6V0A4 SLC4A4

8.15e-055852C1704380
Diseaseintellectual disability (is_implicated_in)

SLC6A8 SLC16A2 AGTR2

8.85e-0530853DOID:1059 (is_implicated_in)
Diseasesusceptibility to bacterial meningitis measurement

SLC6A9 SLC4A4 SDC4

4.60e-0452853EFO_0008411
DiseaseLenticulostriate Disorders

HTR2A SLC19A3

5.31e-0412852C0750951
DiseaseExtrapyramidal Disorders

HTR2A SLC19A3

5.31e-0412852C0015371
DiseaseBasal Ganglia Diseases

HTR2A SLC19A3

5.31e-0412852C0004782
DiseaseSeasonal Affective Disorder

HTR2A HTR2C

9.59e-0416852C0085159
DiseaseAlcoholic Intoxication, Chronic

ADRA2A HTR2A HTR2C SLC29A1 CHRNB4

1.08e-03268855C0001973
Diseasee-selectin measurement

KIRREL3 MYMK

1.82e-0322852EFO_0004575
Diseaseanxiety disorder (implicated_via_orthology)

ADRA2A HTR2C

1.82e-0322852DOID:2030 (implicated_via_orthology)
Diseaseobesity (is_implicated_in)

ADRA2B HTR2A HTR2C

2.33e-0391853DOID:9970 (is_implicated_in)
Diseaselarge artery stroke, coronary artery disease

PLPP3 CHRNB4

2.36e-0325852EFO_0001645, EFO_0005524

Protein segments in the cluster

PeptideGeneStartEntry
FMFVCVLGTVGLFLP

CHRNB4

466

P30926
LFFQPMAECLFFPLE

ARHGEF1

441

Q92888
FLLVFSFISEPMVCG

SLC7A10

436

Q9NS82
LILCLLEMSFAVPFF

AMBN

16

Q9NP70
TLCLLSPFAFTVGMA

ABCA9

361

Q8IUA7
LIGSFVSFFIPLTIM

HTR2A

236

P28223
LIGSFVAFFIPLTIM

HTR2C

216

P28335
LFGPVMCKVFGSFLT

AGTR2

111

P50052
GFLVPLLAMSFCYLV

CCR7

231

P32248
PVLSCFTRFMAGLIF

CMTR2

646

Q8IYT2
SSIGSFFAPCLIMIL

ADRA2B

176

P18089
GLCDGFFITIMAPIA

SLC16A2

421

P36021
MAAFPHKIIFFLVCS

SPINK13

1

Q1W4C9
MLCFLRGMAFVPFLL

DRAM1

1

Q8N682
VIMFFGLFAPLVFLS

SLC16A1

271

P53985
ASTLLFIMFPFCLIL

OR10A7

201

Q8NGE5
DMVCFLFITPLAAIS

MARCHF2

141

Q9P0N8
VFCSLPLGFFIVSSM

GK3P

526

Q14409
FACCVFMLLLPFSII

OR2V1

201

Q8NHB1
FACCVFMLLFPFSII

OR2V2

201

Q96R30
LLLFVAAAFMAVAPL

OR3A3

206

P47888
IIFLMFGPAIFIYTC

OR4N5

246

Q8IXE1
HLMVVTLFFGPCIFI

OR4Q2

241

P0C623
CFILSFFALCGPQML

PERP

91

Q96FX8
FFALCGPQMLVFLRV

PERP

96

Q96FX8
QSFGFIVPLLIMLFC

CXCR2

216

P25025
FIYDCLMGFPVLVVS

GPR153

251

Q6NV75
VLTLSCVGFFPAMLL

GPR119

166

Q8TDV5
LFAMFFILVQLPSGC

DEFB105A

11

Q8NG35
MILTCAGVFLICFAP

GPR174

231

Q9BXC1
GFFGALCLMVDFILI

OR51A2

201

Q8NGJ7
GFFGALCLMVDFILI

OR51A4

201

Q8NGJ6
LFICGVTAPMFTFVL

GPR75

91

O95800
IPLVLALFAFVGFML

IL20RB

231

Q6UXL0
IFFATCLQPGTMIVL

MFSD4B

286

Q5TF39
PGAIVAAMGIVCFLF

SLC37A1

226

P57057
QCMLGLFFGFLLVIF

CD9

86

P21926
LAMACIFAFILSFGI

SLC2A11

371

Q9BYW1
FSCLFIIPLFIMLIC

GNRHR

216

P30968
GLLIPFTIFMFCYIK

CCR8

206

P51685
LRLAMVGCAFVLFLF

GALNT6

11

Q8NCL4
VPTVLALDFMCFLAL

TMEM63B

41

Q5T3F8
AFPLAFCIFMVRLIF

CERS6

41

Q6ZMG9
FGDMVCFLFITPLAT

MARCHF3

146

Q86UD3
MKPFQLDLLFVCFFL

KIRREL3

1

Q8IZU9
FQLEFFMPLGIILFC

HCAR1

181

Q9BXC0
FMPLGIILFCSFKIV

HCAR1

186

Q9BXC0
ENFFCMGSPLAVFLA

DDHD1

616

Q8NEL9
MNFILFIFIPGVFSL

EQTN

1

Q9NQ60
MAPARLFALLLFFVG

SDC4

1

P31431
LQLVMSAPCFVFFLF

SLC22A25

261

Q6T423
TVILCLFGFFSMMRP

SLC19A3

16

Q9BZV2
PFLFGACIVLMSFLV

MFSD14B

431

Q5SR56
ACIVLMSFLVALFIP

MFSD14B

436

Q5SR56
LRSISFPACFLQMFI

OR56A1

96

Q8NGH5
FADIGFLALTCFMLI

OR10G6

221

Q8NH81
ATGCFIFLTPLGFMT

OR1D5

201

P58170
PMSFFLAGLTFIDII

OR4A4P

56

Q8NGN8
FFFNLGIVTPLIMFI

TAS2R39

211

P59534
ALSGPLFLFQVLTFM

SLC47A2

36

Q86VL8
CEFPMLETGLFFLLS

SLC9A9

306

Q8IVB4
LCFLLFFIPNVAMVF

TAAR9

201

Q96RI9
IIGMIFGCFALFELL

SLC18B1

71

Q6NT16
LFCLFMAGLPFLIIE

PLPP3

41

O14495
GCTFVAVMLVFPAIL

PTCH2

536

Q9Y6C5
VGCLLLFIAMGIFTF

KCNV2

411

Q8TDN2
MLFFTQCFGAVLDLI

SIAH3

1

Q8IW03
MLCPFVVVLGGMFFL

SPNS2

506

Q8IVW8
SMCFPLISLILFLFG

PGAP1

676

Q75T13
FTPLVCMGIFIFNVV

SLC6A8

526

P48029
FFIFIFPGLCLICAM

SLC38A8

381

A6NNN8
AVTQFFLMPFCGFLL

SLC10A5

181

Q5PT55
FLMPFCGFLLSQIVA

SLC10A5

186

Q5PT55
PFAGICMFILILFAC

SLC28A2

176

O43868
VCFIFTITIGMFPAV

SLC29A1

296

Q99808
LGMFCPTLFDLFAEL

TMC1

416

Q8TDI8
CIGSFFAPCLIMILV

ADRA2A

216

P08913
FLLPFVSLGLMCFGA

CLDND1

141

Q9NY35
MGLFRGFVFLLVLCL

CLCA4

1

Q14CN2
CLGEPLARMELFLFF

CYP2D7

461

A0A087X1C5
FFMGLKCLILLVPSF

RNFT1

261

Q5M7Z0
ATFTFVILSIMGCPL

TMEM212

76

A6NML5
FLFIVGVTCRMLPSA

TRPM5

816

Q9NZQ8
GVMVPFILCLISFFL

TAS2R9

186

Q9NYW1
LPIGASVSLLVMFFF

SPPL3

76

Q8TCT6
VFFIMGLFGVLICHL

RELL1

66

Q8IUW5
MPPFLLLEAVCVFLF

VWA2

1

Q5GFL6
LIFCGIPLFFMELSF

SLC6A9

146

P48067
FFFMLILLGLGTQFC

SLC6A9

461

P48067
IGFAIMTQCLPVALF

TECR

256

Q9NZ01
MTQCLPVALFSLVGF

TECR

261

Q9NZ01
VNFMFILFPVCGSKF

TMEM44

101

Q2T9K0
FAIVGMEFFCGIVFP

TPCN1

581

Q9ULQ1
IGAFLIPAMVCGTAF

TM9SF3

361

Q9HD45
IPAMVCGTAFFINFI

TM9SF3

366

Q9HD45
FIPEMIFILCLFGYL

ATP6V0A4

576

Q9HBG4
CPGIVFADFFIMNLI

TM9SF2

441

Q99805
CNFVPDITLMSFILF

SLC4A4

686

Q9Y6R1
VSIPELLFMLCIFGY

ATP6V0A2

586

Q9Y487
FLGMAVFKPDLITCL

ZNF729

51

A6NN14
IFGALIAVCLIMGLF

SLC16A10

381

Q8TF71
PGLCFGALALMLRFF

MYMK

156

A6NI61