Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	cellular response to magnesium ion	KCNA1 ANK3	6.09e-05	8	31	2	GO:0071286
GeneOntologyBiologicalProcess	polar body extrusion after meiotic divisions	SPIRE1 MEI1	9.76e-05	10	31	2	GO:0040038
GeneOntologyBiologicalProcess	microtubule-based process	SPIRE1 DNAH3 GDA MEI1 ALMS1 ANK3 KIF17 TAF7L	1.28e-04	1058	31	8	GO:0007017
GeneOntologyBiologicalProcess	meiotic cytokinesis	SPIRE1 MEI1	1.69e-04	13	31	2	GO:0033206
Domain	SOCS	RAB40A RAB40AL	4.35e-04	20	29	2	SM00253
Domain	SOCS_box	RAB40A RAB40AL	1.58e-03	38	29	2	PF07525
Domain	SOCS	RAB40A RAB40AL	1.66e-03	39	29	2	PS50225
Domain	SOCS_box	RAB40A RAB40AL	1.66e-03	39	29	2	SM00969
Domain	SOCS_box	RAB40A RAB40AL	1.66e-03	39	29	2	IPR001496
Domain	RAB	RAB40A RAB40AL	5.71e-03	73	29	2	PS51419
Domain	ARM-like	MEI1 PUM1 TAF7L	8.27e-03	270	29	3	IPR011989
Domain	P-loop_NTPase	DNAH3 MYO18B RAB40A KIF17 RAB40AL	9.14e-03	848	29	5	IPR027417
Pubmed	Ankyrin-3 is a novel binding partner of the voltage-gated potassium channel Kv1.1 implicated in renal magnesium handling.	KCNA1 ANK3	8.73e-07	2	33	2	23903368
Pubmed	Rab40b and Tks5 interact at invadopodia during metastasis.	RAB40A RAB40AL	8.72e-06	5	33	2	27909076
Pubmed	BetaIVSigma1 spectrin stabilizes the nodes of Ranvier and axon initial segments.	KCNA1 ANK3	1.31e-05	6	33	2	15381686
Pubmed	Germline diversity of the expressed BALB/c VhJ558 gene family.	IGHV1-58 IGHV1-45	3.13e-05	9	33	2	11483206
Pubmed	Genome-wide association study of increasing suicidal ideation during antidepressant treatment in the GENDEP project.	GDA ANK3	3.13e-05	9	33	2	20877300
Pubmed	Diversity of germ-line immunoglobulin VH genes.	IGHV1-58 IGHV1-45	3.13e-05	9	33	2	6789211
Pubmed	Neurofascin 140 is an embryonic neuronal neurofascin isoform that promotes the assembly of the node of Ranvier.	KCNA1 ANK3	3.13e-05	9	33	2	25653379
Pubmed	Developmentally controlled and tissue-specific expression of unrearranged VH gene segments.	IGHV1-58 IGHV1-45	3.13e-05	9	33	2	2578321
Pubmed	Combinatorial association of V genes: one VH gene codes for three non-cross-reactive monoclonal antibodies each specific for a different antigen (phoxazolone, NP or gat).	IGHV1-58 IGHV1-45	3.91e-05	10	33	2	3211160
Pubmed	Heavy chain variable region contribution to the NPb family of antibodies: somatic mutation evident in a gamma 2a variable region.	IGHV1-58 IGHV1-45	1.32e-04	18	33	2	6788376
Pubmed	Dead end1 is an essential partner of NANOS2 for selective binding of target RNAs in male germ cell development.	PUM1 TAF7L	1.99e-04	22	33	2	26589352
Pubmed	Leber Congenital Amaurosis / Early-Onset Severe Retinal Dystrophy Overview	IMPDH1 ALMS1	2.58e-04	25	33	2	30285347
Pubmed	Ion channel expression in the developing enteric nervous system.	KCNA1 ANK3	5.69e-04	37	33	2	25798587
Pubmed	The DNA sequence of the human X chromosome.	ZC3H12B RAB40A BRWD3 RAB40AL	5.78e-04	407	33	4	15772651
Pubmed	The SOCS box: a tale of destruction and degradation.	RAB40A RAB40AL	7.00e-04	41	33	2	12076535
Pubmed	Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome.	SDK2 KCNA1 ANK3	8.62e-04	197	33	3	36604605
Pubmed	Impaired Spermatogenesis, Muscle, and Erythrocyte Function in U12 Intron Splicing-Defective Zrsr1 Mutant Mice.	MEI1 TAF7L	9.19e-04	47	33	2	29617656
Cytoband	Ensembl 112 genes in cytogenetic band chrXq22	RAB40A TAF7L RAB40AL	2.60e-04	172	33	3	chrXq22
Cytoband	Xq22.1	RAB40A TAF7L	4.44e-04	43	33	2	Xq22.1
ToppCell	P15-Epithelial-epithelial_progenitor_cell-epithelial_unknown_3\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	SPIRE1 KCNA1 ANK3 RFWD3	8.47e-06	176	33	4	792f414f5092aba14260b8e16378e793a822498e
ToppCell	facs-Trachea-nan-3m-Mesenchymal-smooth_muscle_cell_of_trachea\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPY1R KCNA1 ANK3 TAF7L	1.10e-05	188	33	4	794fc1d9a726945c42f7eac221eed938309b47a9
Disease	obesity (implicated_via_orthology)	SDK2 NPY1R ALMS1 PUM1	5.64e-05	215	29	4	DOID:9970 (implicated_via_orthology)
Disease	Mental Retardation, X-Linked	BRWD3 RAB40AL	3.72e-04	29	29	2	C1136249
Disease	Nonorganic psychosis	NPY1R ANK3	2.10e-03	69	29	2	C0349204
Disease	Manic Disorder	MRPS33 ANK3	2.22e-03	71	29	2	C0024713
Disease	Manic	MRPS33 ANK3	2.67e-03	78	29	2	C0338831
Disease	Depression, Bipolar	MRPS33 ANK3	2.74e-03	79	29	2	C0005587
Disease	susceptibility to scarlet fever measurement	GDA SDK2	2.74e-03	79	29	2	EFO_0008409
Disease	smoking cessation	MEI1 ALMS1 ANK3	3.91e-03	325	29	3	EFO_0004319
Disease	Psychotic Disorders	NPY1R ANK3	4.43e-03	101	29	2	C0033975

Protein segments in the cluster

Peptide	Gene	Start	Entry
RYLDGMDSDFTSMTS	BET1L	51	Q9NYM9
SEYHSSDLRMLRMSP	ALMS1	451	Q8TCU4
RIYSMMLRLSALFES	BRWD3	1411	Q6RI45
GSDMLTRFSIRMFSL	FAM187A	96	A6NFU0
LNARMMRGLSYSLTT	RAB40A	231	Q8WXH6
LNARMMRGLSYSLTT	RAB40AL	231	P0C0E4
TTIRSVLMEMSYRLD	RFWD3	661	Q6PCD5
RVTITRDMSTSTAYM	IGHV1-58	86	A0A0C4DH39
RDMSTSTAYMELSSL	IGHV1-58	91	A0A0C4DH39
LSRRSSSTMSKSEYM	KCNA1	441	Q09470
RVTITRDRSMSTAYM	IGHV1-45	86	A0A0A0MS14
RDRSMSTAYMELSSL	IGHV1-45	91	A0A0A0MS14
ASSMTERLREMQSFF	MMP13	61	P45452
SMESSVLLSMSIDRY	OR51G1	111	Q8NGK1
IGARSLSVLRSMMYS	IMPDH1	471	P20839
MTLFMRYRSSSVLSH	MEI1	1176	Q5TIA1
LFSSSRLRYGMSDVM	PUM1	811	Q14671
RSRDDDYETIAMSTM	NPY1R	341	P25929
SMMRLYSSLLDEIRA	DNAH3	1916	Q8TD57
DMTLSMTGRERSEYL	CCDC9	251	Q9Y3X0
NRSSYARDSMMIEEL	ANK3	926	Q12955
SVLSERDYESLVMMR	DNAJC17	266	Q9NVM6
SYSMLDAIRRAVMVS	GDA	336	Q9Y2T3
ELTSMYSMRNLSRPS	SDK2	1566	Q58EX2
MEDDRYRLMLSRSNS	KIF17	931	Q9P2E2
MSSLSEYAFRMSRLS	MRPS33	1	Q9Y291
SEYDMLREMFSDSRS	TAF7L	316	Q5H9L4
MSLRTLSTQEMDYSL	TC2N	326	Q8N9U0
YMASSCMTRLSRSRT	NDRG2	316	Q9UN36
ASEENSYMRSMTSLL	TEX44	266	Q53QW1
TSLAMLMLDSFYRSI	MTM1	386	Q13496
LAMRPLSMSYSFDLS	SPIRE1	396	Q08AE8
SLRTMTAISRYMELT	TMEM44	366	Q2T9K0
LVMTRMDSISDSRLY	ZC3H12B	696	Q5HYM0
SRSATRFSMVMSLDF	MYO18B	711	Q8IUG5