Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	phorbol ester receptor activity	UNC13B UNC13C	1.02e-04	2	202	2	GO:0001565
GeneOntologyMolecularFunction	non-kinase phorbol ester receptor activity	UNC13B UNC13C	1.02e-04	2	202	2	GO:0001566
GeneOntologyCellularComponent	Golgi lumen	IL12B ACAN FURIN VCAN NCAN MUC5AC SOD3	9.19e-05	109	202	7	GO:0005796
GeneOntologyCellularComponent	perineuronal net	ACAN VCAN NCAN	1.01e-04	10	202	3	GO:0072534
GeneOntologyCellularComponent	perisynaptic extracellular matrix	ACAN VCAN NCAN	1.39e-04	11	202	3	GO:0098966
GeneOntologyCellularComponent	synapse-associated extracellular matrix	ACAN VCAN NCAN	2.37e-04	13	202	3	GO:0099535
GeneOntologyCellularComponent	ribbon synapse	BSN UNC13B AMPH ATP2B1	2.46e-04	32	202	4	GO:0097470
HumanPheno	Renal artery stenosis	LDLRAP1 IL12B NF1 JAG1 TOM1	1.08e-05	25	63	5	HP:0001920
MousePheno	impaired branching involved in terminal bronchiole morphogenesis	BAG6 VANGL2 CELSR1	1.34e-05	5	156	3	MP:0011032
MousePheno	abnormal head movements	BLOC1S4 HMX2 JAG1 CHD7 VANGL2 CELSR1 NISCH ATP2B1	1.95e-05	103	156	8	MP:0000436
MousePheno	absent chiasmata formation	ANKRD31 ZCWPW1 MEIOSIN	2.66e-05	6	156	3	MP:0008967
MousePheno	abnormal branching involved in terminal bronchiole morphogenesis	BAG6 VANGL2 CELSR1	4.62e-05	7	156	3	MP:0011031
Domain	CRAL_TRIO_2	GDAP2 MCF2 NF1 PRUNE2	5.23e-06	12	194	4	PF13716
Domain	-	LDLRAP1 OBSCN MCF2 SHC2 PLEKHM2 PLEKHH2 ARHGEF5 RALGPS2 ASAP3 APBA3 CERT1 PLEKHG6 SBF2 ARHGAP27	6.18e-05	391	194	14	2.30.29.30
Domain	FN3_dom	IL10RB IL12B IGFN1 OBSCN LRIT3 MERTK FNDC3B IFNAR2 TNN SORL1	6.84e-05	209	194	10	IPR003961
Domain	ARHGEF5_35	ARHGEF5 ARHGEF35	1.07e-04	2	194	2	PF15441
Domain	ARHGEF5/35_N	ARHGEF5 ARHGEF35	1.07e-04	2	194	2	IPR029212
Domain	Potential_DNA-bd	INO80D KANSL2	1.07e-04	2	194	2	IPR025927
Domain	zf-C3Hc3H	INO80D KANSL2	1.07e-04	2	194	2	PF13891
Domain	ATP2B1/4	ATP2B1 ATP2B4	1.07e-04	2	194	2	IPR030319
Domain	PH	OBSCN MCF2 PLEKHM2 PLEKHH2 ARHGEF5 RALGPS2 ASAP3 CERT1 SBF2 ARHGAP27	1.45e-04	229	194	10	PF00169
Domain	PH_dom-like	LDLRAP1 OBSCN MCF2 SHC2 PLEKHM2 PLEKHH2 ARHGEF5 RALGPS2 ASAP3 APBA3 CERT1 PLEKHG6 SBF2 ARHGAP27	1.53e-04	426	194	14	IPR011993
Domain	PH	OBSCN MCF2 PLEKHM2 PLEKHH2 ARHGEF5 RALGPS2 ASAP3 CERT1 PLEKHG6 SBF2 ARHGAP27	1.62e-04	278	194	11	SM00233
Domain	CRAL_TRIO	GDAP2 MCF2 NF1 PRUNE2	1.64e-04	27	194	4	PS50191
Domain	PH_DOMAIN	OBSCN MCF2 PLEKHM2 PLEKHH2 ARHGEF5 RALGPS2 ASAP3 CERT1 PLEKHG6 SBF2 ARHGAP27	1.67e-04	279	194	11	PS50003
Domain	PH_domain	OBSCN MCF2 PLEKHM2 PLEKHH2 ARHGEF5 RALGPS2 ASAP3 CERT1 PLEKHG6 SBF2 ARHGAP27	1.73e-04	280	194	11	IPR001849
Domain	EGF	GPR179 JAG1 LTBP4 ZAN CELSR1 MEGF8 TNN VCAN NCAN SORL1	1.80e-04	235	194	10	SM00181
Domain	EGF_3	JAG1 LTBP4 ZAN CRTAC1 CELSR1 MEGF8 TNN VCAN NCAN SORL1	1.80e-04	235	194	10	PS50026
Domain	CRAL-TRIO_dom	GDAP2 MCF2 NF1 PRUNE2	1.90e-04	28	194	4	IPR001251
Domain	FN3	IL10RB IL12B IGFN1 OBSCN LRIT3 MERTK FNDC3B TNN SORL1	2.41e-04	199	194	9	PS50853
Domain	EGF-like_dom	JAG1 LTBP4 ZAN CRTAC1 CELSR1 MEGF8 TNN VCAN NCAN SORL1	2.86e-04	249	194	10	IPR000742
Domain	EGF_CA	JAG1 LTBP4 CRTAC1 CELSR1 MEGF8 VCAN NCAN	2.87e-04	122	194	7	SM00179
Domain	C1_1	MYO9B RASSF5 BRAF UNC13B UNC13C	3.10e-04	57	194	5	PF00130
Domain	EGF-like_Ca-bd_dom	JAG1 LTBP4 CRTAC1 CELSR1 MEGF8 VCAN NCAN	3.17e-04	124	194	7	IPR001881
Domain	Unc-13	UNC13B UNC13C	3.20e-04	3	194	2	IPR027080
Domain	EGF-like_CS	JAG1 LTBP4 ZAN CRTAC1 CELSR1 MEGF8 TNN VCAN NCAN SORL1	4.15e-04	261	194	10	IPR013032
Domain	SH3	SPTA1 OBSCN UBASH3A AMPH ARHGEF5 SNX18 ARHGAP27 MAP3K21 HCLS1	4.40e-04	216	194	9	SM00326
Domain	SH3	SPTA1 OBSCN UBASH3A AMPH ARHGEF5 SNX18 ARHGAP27 MAP3K21 HCLS1	4.40e-04	216	194	9	PS50002
Domain	EGF_2	JAG1 LTBP4 ZAN CRTAC1 CELSR1 MEGF8 TNN VCAN NCAN SORL1	4.67e-04	265	194	10	PS01186
Domain	SH3_domain	SPTA1 OBSCN UBASH3A AMPH ARHGEF5 SNX18 ARHGAP27 MAP3K21 HCLS1	5.03e-04	220	194	9	IPR001452
Domain	EGF_Ca-bd_CS	JAG1 LTBP4 CRTAC1 MEGF8 VCAN NCAN	5.25e-04	97	194	6	IPR018097
Domain	ZF_DAG_PE_1	MYO9B RASSF5 BRAF UNC13B UNC13C	5.33e-04	64	194	5	PS00479
Domain	ZF_DAG_PE_2	MYO9B RASSF5 BRAF UNC13B UNC13C	5.33e-04	64	194	5	PS50081
Domain	C1	MYO9B RASSF5 BRAF UNC13B UNC13C	5.72e-04	65	194	5	SM00109
Domain	EGF_CA	JAG1 LTBP4 CRTAC1 MEGF8 VCAN NCAN	5.85e-04	99	194	6	PS01187
Domain	PE/DAG-bd	MYO9B RASSF5 BRAF UNC13B UNC13C	6.14e-04	66	194	5	IPR002219
Domain	ASX_HYDROXYL	JAG1 LTBP4 CELSR1 MEGF8 VCAN NCAN	6.17e-04	100	194	6	PS00010
Domain	ATP_Ca_trans_C	ATP2B1 ATP2B4	6.35e-04	4	194	2	IPR022141
Domain	TEA_1	TEAD4 TEAD3	6.35e-04	4	194	2	PS00554
Domain	TEA_2	TEAD4 TEAD3	6.35e-04	4	194	2	PS51088
Domain	ATP_Ca_trans_C	ATP2B1 ATP2B4	6.35e-04	4	194	2	PF12424
Domain	TEA	TEAD4 TEAD3	6.35e-04	4	194	2	PF01285
Domain	TEA/ATTS_dom	TEAD4 TEAD3	6.35e-04	4	194	2	IPR000818
Domain	TEF_metazoa	TEAD4 TEAD3	6.35e-04	4	194	2	IPR016361
Domain	TEA	TEAD4 TEAD3	6.35e-04	4	194	2	SM00426
Domain	P-type_ATPase_IIB	ATP2B1 ATP2B4	6.35e-04	4	194	2	IPR006408
Domain	FN3	IL10RB IGFN1 OBSCN LRIT3 MERTK FNDC3B TNN SORL1	7.16e-04	185	194	8	SM00060
Domain	Cation_ATPase_N	ATP13A2 ATP2B1 ATP2B4	8.03e-04	18	194	3	SM00831
Domain	EGF-type_Asp/Asn_hydroxyl_site	JAG1 LTBP4 CELSR1 MEGF8 VCAN NCAN	8.39e-04	106	194	6	IPR000152
Domain	VWC_out	JAG1 ZAN MUC5AC	9.46e-04	19	194	3	SM00215
Domain	ATPase_P-typ_cation-transptr_N	ATP13A2 ATP2B1 ATP2B4	9.46e-04	19	194	3	IPR004014
Domain	Munc13_dom-2	UNC13B UNC13C	1.05e-03	5	194	2	IPR014772
Domain	MHD2	UNC13B UNC13C	1.05e-03	5	194	2	PS51259
Domain	Munc13_subgr_dom-2	UNC13B UNC13C	1.05e-03	5	194	2	IPR019558
Domain	Membr_traf_MHD	UNC13B UNC13C	1.05e-03	5	194	2	PF10540
Domain	DUF1041	UNC13B UNC13C	1.05e-03	5	194	2	SM01145
Domain	Growth_fac_rcpt_	GPR179 JAG1 LTBP4 CELSR1 MEGF8 TNN FURIN	1.24e-03	156	194	7	IPR009030
Domain	EGF_1	JAG1 LTBP4 ZAN CRTAC1 CELSR1 MEGF8 TNN VCAN NCAN	1.43e-03	255	194	9	PS00022
Domain	fn3	IL12B IGFN1 OBSCN MERTK FNDC3B TNN SORL1	1.54e-03	162	194	7	PF00041
Domain	SH3_1	SPTA1 UBASH3A AMPH ARHGEF5 SNX18 MAP3K21 HCLS1	1.65e-03	164	194	7	PF00018
Domain	SEC14	GDAP2 NF1 PRUNE2	2.14e-03	25	194	3	SM00516
Domain	Munc13_1	UNC13B UNC13C	2.18e-03	7	194	2	IPR014770
Domain	MHD1	UNC13B UNC13C	2.18e-03	7	194	2	PS51258
Domain	DUF1041	UNC13B UNC13C	2.18e-03	7	194	2	PF06292
Domain	CAPS_dom	UNC13B UNC13C	2.18e-03	7	194	2	IPR010439
Pathway	WP_TRANSCRIPTION_COFACTORS_SKI_AND_SKIL_PROTEIN_PARTNERS	NF1 MERTK TEAD4 TEAD3 LATS2	7.71e-07	18	143	5	M39825
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	LRWD1 MYO9B C19orf47 OBSCN MAPK8IP3 EIF4ENIF1 PLEKHM2 NCAPD2 NAV1 DMWD RGL2 LTBP4 SMG6 UNC13B CORO1B ATP13A2 C2CD2 CLDN23 CELSR1 LATS2 MEGF8 SETD5 NISCH FURIN PPP1R15B KANK3 SBF2 TNKS1BP1 ESPL1 SYMPK	3.51e-12	1105	205	30	35748872
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	MBD1 C19orf47 NF1 BRAF SYNE2 NAV1 FNIP1 RGL2 KIF13B CASC3 NEDD4L ARHGEF5 RALGPS2 ANKRD26 KLC2 ALPK1 YWHAH AKAP9 MEGF8 TNKS1BP1 SSH2 EIF3J MAP3K21 ATP2B1 PCM1	6.40e-11	861	205	25	36931259
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	ASIC1 APC2 MAPK8IP3 NF1 EHMT2 SYNE2 NAV1 BSN SMG6 KIF13B CASC3 STRN3 NEDD4L CHD7 CORO1B YWHAH SART1 FRY AKAP9 NISCH NCAN SSH2 FSCN1 ATP2B4 PCM1 TP53BP1	1.24e-10	963	205	26	28671696
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	RASSF5 NF1 EIF4ENIF1 BRAF NAV1 STRN3 RALGPS2 ANKRD26 KLC2 TEAD3 YWHAH LATS2 AKAP9 SNX18 CEP295 MAP3K21 PCM1	1.59e-09	446	205	17	24255178
Pubmed	Protein interactome reveals converging molecular pathways among autism disorders.	MBD1 APC2 PPP2R3B MAPK8IP3 KANSL2 NF1 CDC123 CLTA LTBP4 SF3B2 CASC3 BSDC1 CORO1B MRM3 MEGF8 NUP133 AATF FSCN1	7.42e-09	560	205	18	21653829
Pubmed	Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.	ERICH1 MYO9B OBSCN CHD2 ARMCX2 ZNF785 MAPK8IP3 GREB1L TRANK1 NF1 EHMT2 CLTA NCAPD2 OS9 DLST MERTK BSDC1 KLC2 FER1L4 VCAN NCAN SNX18 MFSD8 EIF3J INS-IGF2	6.43e-08	1215	205	25	15146197
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	LRWD1 NAP1L4 CHD2 ARMCX2 KNOP1 HELB EHMT2 NCAPD2 BAG6 CHD7 NUP133 TNKS1BP1 EIF3J FSCN1 TP53BP1	1.48e-07	469	205	15	27634302
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	LRWD1 MAPK8IP3 KANSL2 NF1 BRAF DMWD DHX29 BAG6 SF3B2 STRN3 KLC2 CHD7 SART1 STC2 TNKS1BP1 ESPL1 PCM1 TP53BP1 SYMPK	1.96e-07	774	205	19	15302935
Pubmed	A kinesin-1 binding motif in vaccinia virus that is widespread throughout the human genome.	LDLRAP1 BSDC1 KLC2 PRKAG3	2.39e-07	10	205	4	21915095
Pubmed	Lecticans: organizers of the brain extracellular matrix.	ACAN VCAN NCAN	8.04e-07	4	205	3	10766023
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	SP3 LRWD1 MBD1 NAP1L4 CHD2 INO80D KNOP1 GREB1L EIF4ENIF1 EHMT2 NCAPD2 OS9 MCAT UTP3 DHX29 SMG6 FNDC3B CASC3 STRN3 TOM1 CHD7 MRM3 CELSR1 SETD5 AATF EIF3J	8.90e-07	1497	205	26	31527615
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	SPTA1 MAPK8IP3 NF1 NAV1 DLST MCAT BSN DHX29 STRN3 AMPH WARS1 NEDD4L TOM1 KLC2 CORO1B YWHAH NISCH VCAN NCAN TNKS1BP1 SSH2 FSCN1 ATP2B1 ATP2B4 PCM1	1.32e-06	1431	205	25	37142655
Pubmed	The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.	NF1 BRAF JAG1 NAV1 ELMOD3 KIF13B RALGPS2 ASAP3 ANKRD26 VANGL2 LATS2 C1orf226 SLC39A14 ATP2B1 ATP2B4	1.67e-06	569	205	15	30639242
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	BLOC1S4 NAP1L4 EIF4ENIF1 CDC123 DMWD CASC3 STRN3 NEDD4L TOM1 APBA3 ALPK1 CDC37L1 SHQ1 SBF2 SNX18 AATF TNKS1BP1 PRMT3 SSH2 ESPL1	3.90e-06	1038	205	20	26673895
Pubmed	Leukocyte common antigen-related phosphatase is a functional receptor for chondroitin sulfate proteoglycan axon growth inhibitors.	ACAN VCAN NCAN	6.94e-06	7	205	3	21976490
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	OBSCN CHD2 KNOP1 BRAF DMWD SUCO KIF13B WARS1 ANGEL1 RALGPS2 CHD7 SETD5 VCAN SBF2 AATF CEP295 ESPL1 ATP2B1 SZRD1 TP53BP1	7.38e-06	1084	205	20	11544199
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	CHD2 NF1 SYNE2 NCAPD2 SF3B2 WARS1 CHD7 SART1 NUP133 AATF TNKS1BP1 FSCN1 PCM1 TP53BP1 SYMPK	8.74e-06	653	205	15	22586326
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	ARMCX2 C2CD4C EIF4ENIF1 EHMT2 SYNE2 NAV1 DLST UTP3 SUCO BAG6 SMG6 CASC3 STRN3 ANGEL1 YWHAH VANGL2 MRM3 AKAP9 NISCH PPP1R15B NUP133 AATF SLC39A14 ESPL1	9.21e-06	1496	205	24	32877691
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	BRAF EHMT2 ANAPC2 NCAPD2 DHX29 BAG6 STRN3 KLC2 NUP133 TNKS1BP1 EIF3J PCM1 TP53BP1	1.03e-05	503	205	13	16964243
Pubmed	TRIM65 regulates microRNA activity by ubiquitination of TNRC6.	LRWD1 MYO9B NAP1L4 BAG6 SF3B2 KBTBD6 APBA3 CTSA AATF TNKS1BP1 SORL1	1.19e-05	364	205	11	24778252
Pubmed	Proteomic analysis of NMDA receptor-adhesion protein signaling complexes.	SPTA1 NF1 BSN KLC2 AKAP9 TP53BP1	1.24e-05	86	205	6	10862698
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	NAP1L4 NACAD MAPK8IP3 NF1 CLTA NAV1 DLST BSN DHX29 STRN3 AMPH WARS1 NEDD4L BSDC1 KLC2 CORO1B YWHAH VANGL2 PCM1 TP53BP1	1.51e-05	1139	205	20	36417873
Pubmed	International Lung Cancer Consortium: coordinated association study of 10 potential lung cancer susceptibility variants.	BAG6 AKAP9 TP53BP1	1.65e-05	9	205	3	20106900
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	ERICH1 C2CD4C KNOP1 PLEKHM2 EHMT2 ANGEL1 TMEM115 ANKRD26 BSDC1 SART1 DTWD2 FURIN PPP1R15B EBAG9 SLC39A14 PCM1	1.69e-05	777	205	16	35844135
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	NAP1L4 EHMT2 CDC123 SYNE2 CLTA OS9 DLST SUCO DHX29 BAG6 SF3B2 ANKRD26 VANGL2 AKAP9 NISCH PPP1R15B NUP133 FSCN1 ESPL1 ATP2B1 ATP2B4 PCM1 TP53BP1	2.54e-05	1487	205	23	33957083
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	HEBP2 OBSCN CHD2 BRWD3 MAPK8IP3 SHC2 NAV1 FNIP1 OS9 SMG6 PRUNE2 RAD52 CASC3 NEDD4L TOM1 CERT1 C2CD2 PARP10 LATS2 SETD5 SBF2 ATP2B1 PCM1	2.59e-05	1489	205	23	28611215
Pubmed	Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	GREB1L SETD5 SBF2 TNKS1BP1 CEP295 SSH2	3.28e-05	102	205	6	11214970
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	ASXL1 PLEKHM2 NAV1 FNIP1 UNC13B NEDD4L AKAP9 MEGF8 SETD5 NISCH SLC39A14	3.33e-05	407	205	11	12693553
Pubmed	Functional and structural demonstration of the presence of Ca-ATPase (PMCA) in both microvillous and basal plasma membranes from syncytiotrophoblast of human term placenta.	ATP2B1 ATP2B4	3.46e-05	2	205	2	18657858
Pubmed	Chromatin regulator Asxl1 loss and Nf1 haploinsufficiency cooperate to accelerate myeloid malignancy.	ASXL1 NF1	3.46e-05	2	205	2	30226831
Pubmed	Unclassified sclerosing malignant melanomas with AKAP9-BRAF gene fusion: a report of two cases and review of BRAF fusions in melanocytic tumors.	BRAF AKAP9	3.46e-05	2	205	2	29464327
Pubmed	Identification and characterization of versican/PG-M aggregates in cartilage.	ACAN VCAN	3.46e-05	2	205	2	16648631
Pubmed	Furin proteolytically processes the heparin-binding region of extracellular superoxide dismutase.	FURIN SOD3	3.46e-05	2	205	2	11861638
Pubmed	Fascin Regulates Nuclear Movement and Deformation in Migrating Cells.	SYNE2 FSCN1	3.46e-05	2	205	2	27554857
Pubmed	Cleavage of the carboxyl tail from the G3 domain of aggrecan but not versican and identification of the amino acids involved in the degradation.	ACAN VCAN	3.46e-05	2	205	2	11932252
Pubmed	The anaphase promoting complex is required for memory function in mice.	APC2 ANAPC2	3.46e-05	2	205	2	21191042
Pubmed	Versican G1 and G3 domains are upregulated and latent transforming growth factor-β binding protein-4 is downregulated in breast cancer stroma.	LTBP4 VCAN	3.46e-05	2	205	2	21505857
Pubmed	Highly accurate two-gene classifier for differentiating gastrointestinal stromal tumors and leiomyosarcomas.	OBSCN PRUNE2	3.46e-05	2	205	2	17360660
Pubmed	Targeted ablation of plasma membrane Ca2+-ATPase (PMCA) 1 and 4 indicates a major housekeeping function for PMCA1 and a critical role in hyperactivated sperm motility and male fertility for PMCA4.	ATP2B1 ATP2B4	3.46e-05	2	205	2	15178683
Pubmed	Munc13-independent vesicle priming at mouse photoreceptor ribbon synapses.	UNC13B UNC13C	3.46e-05	2	205	2	22674279
Pubmed	CHD7 and 53BP1 regulate distinct pathways for the re-ligation of DNA double-strand breaks.	CHD7 TP53BP1	3.46e-05	2	205	2	33188175
Pubmed	Regulation of plasma membrane Ca2+-ATPase by small GTPases and phosphoinositides in human platelets.	ATP2B1 ATP2B4	3.46e-05	2	205	2	10748016
Pubmed	Elucidating distinct roles for NF1 in melanomagenesis.	NF1 BRAF	3.46e-05	2	205	2	23171796
Pubmed	Plasma membrane calcium ATPase regulates bone mass by fine-tuning osteoclast differentiation and survival.	ATP2B1 ATP2B4	3.46e-05	2	205	2	23266958
Pubmed	Ectopic expression of RAD52 and dn53BP1 improves homology-directed repair during CRISPR-Cas9 genome editing.	RAD52 TP53BP1	3.46e-05	2	205	2	31015609
Pubmed	Oncogenic AKAP9-BRAF fusion is a novel mechanism of MAPK pathway activation in thyroid cancer.	BRAF AKAP9	3.46e-05	2	205	2	15630448
Pubmed	PKA phosphorylation and 14-3-3 interaction regulate the function of neurofibromatosis type I tumor suppressor, neurofibromin.	NF1 YWHAH	3.46e-05	2	205	2	14741381
Pubmed	The influence of membrane lipid structure on plasma membrane Ca2+ -ATPase activity.	ATP2B1 ATP2B4	3.46e-05	2	205	2	16412504
Pubmed	Distinct roles of PMCA isoforms in Ca2+ homeostasis of bladder smooth muscle: evidence from PMCA gene-ablated mice.	ATP2B1 ATP2B4	3.46e-05	2	205	2	16956963
Pubmed	Localization of two genes encoding plasma membrane Ca2(+)-transporting ATPases to human chromosomes 1q25-32 and 12q21-23.	ATP2B1 ATP2B4	3.46e-05	2	205	2	1674727
Pubmed	Association of IFNAR2 and IL10RB genes in chronic hepatitis B virus infection.	IL10RB IFNAR2	3.46e-05	2	205	2	23745570
Pubmed	Interaction of Mint3 with Furin regulates the localization of Furin in the trans-Golgi network.	APBA3 FURIN	3.46e-05	2	205	2	18544638
Pubmed	The plasma membrane Ca2+ pump PMCA4b inhibits the migratory and metastatic activity of BRAF mutant melanoma cells.	BRAF ATP2B4	3.46e-05	2	205	2	27813079
Pubmed	Association study of IFNAR2 and IL10RB genes with the susceptibility and interferon response in HBV infection.	IL10RB IFNAR2	3.46e-05	2	205	2	19714778
Pubmed	Role of plasma membrane Ca2+-ATPase in contraction-relaxation processes of the bladder: evidence from PMCA gene-ablated mice.	ATP2B1 ATP2B4	3.46e-05	2	205	2	16291816
Pubmed	Selective upregulation of the expression of plasma membrane calcium ATPase isoforms upon differentiation and 1,25(OH)2D3-vitamin treatment of colon cancer cells.	ATP2B1 ATP2B4	3.46e-05	2	205	2	26116539
Pubmed	Celsr1 is required for the generation of polarity at multiple levels of the mouse oviduct.	VANGL2 CELSR1	3.46e-05	2	205	2	25406397
Pubmed	Cathepsin A contributes to left ventricular remodeling by degrading extracellular superoxide dismutase in mice.	CTSA SOD3	3.46e-05	2	205	2	32647007
Pubmed	High-throughput analyses of hnRNP H1 dissects its multi-functional aspect.	SP3 OBSCN NAP1L4 CHD2 BRWD3 DLST DMWD NEDD4L RALGPS2 BSDC1 TEAD4 SART1 PLEKHG6 MEGF8 TNKS1BP1 EIF3J ATP2B1 SZRD1	3.89e-05	1021	205	18	26760575
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	ABRA HEBP2 OBSCN CHD2 ARMCX2 EHMT2 SYNE2 OS9 FNDC3B ANKRD26 AKAP9 NUP133	4.38e-05	497	205	12	23414517
Pubmed	Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.	OS9 BAG6 HEATR3 STRN3 TOM1 AKAP9 DTWD2 STC2 JRK AATF SLC39A14 EIF3J ATP2B1 ATP2B4 PCM1	4.60e-05	754	205	15	33060197
Pubmed	Mouse screen reveals multiple new genes underlying mouse and human hearing loss.	IL10RB ASXL1 MBD1 UBASH3A NACAD NF1 PLEKHM2 OS9 VWA5B1 KIF13B RALGPS2 KLC2 CHD7 ALPK1 TEAD3 CERT1 AKAP9 SETD5 PRMT3 SYMPK	5.08e-05	1242	205	20	30973865
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	LDLRAP1 SP3 APC2 FAM186B EIF4ENIF1 BSN PRUNE2 NEDD4L ARHGEF5 ASAP3 CHD7	5.46e-05	430	205	11	35044719
Pubmed	MEKK2 and MEKK3 orchestrate multiple signals to regulate Hippo pathway.	STRN3 TEAD4 LATS2	5.53e-05	13	205	3	33571521
Pubmed	Phosphatidylinositol 4-kinase IIα function at endosomes is regulated by the ubiquitin ligase Itch.	NEDD4L TOM1 SNX18	5.53e-05	13	205	3	23146885
Pubmed	Epithelial heparan sulfate regulates Sonic Hedgehog signaling in lung development.	ETV4 VANGL2 CELSR1 MUC5AC	5.96e-05	36	205	4	28859094
Pubmed	A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathways.	SYNE2 BAG6 DNHD1 AMHR2 KBTBD6 YWHAH CDC37L1 NISCH VCAN ATP2B1	6.49e-05	363	205	10	25036637
Pubmed	A systems-wide screen identifies substrates of the SCFβTrCP ubiquitin ligase.	GDAP2 EIF4ENIF1 NAV1 FNIP1 SF3B2 WARS1 SBF2 AATF	7.59e-05	232	205	8	25515538
Pubmed	Global mapping of herpesvirus-host protein complexes reveals a transcription strategy for late genes.	KNOP1 OS9 DLST MCAT RGL2 DHX29 HEATR3 CTSA VANGL2 SNX18 TNKS1BP1 PRMT3	8.51e-05	533	205	12	25544563
Pubmed	Down-regulation of active ACK1 is mediated by association with the E3 ubiquitin ligase Nedd4-2.	CLTA AMPH NEDD4L	8.71e-05	15	205	3	19144635
Pubmed	Muscleblind-like 1 is required for normal heart valve development in vivo.	ACAN VCAN NCAN	8.71e-05	15	205	3	26472242
Pubmed	Global landscape of HIV-human protein complexes.	NAP1L4 ANAPC2 FNIP1 OS9 BAG6 SMG6 CASC3 NEDD4L AKAP9 EIF3J ATP2B1	9.38e-05	457	205	11	22190034
Pubmed	Clinical significance of the TNF-α receptors, TNFRSF2 and TNFRSF9, on cell migration molecules Fascin-1 and Versican in acute leukemia.	VCAN FSCN1	1.03e-04	3	205	2	29861382
Pubmed	Mouse T cell priming is enhanced by maturation-dependent stiffening of the dendritic cell cortex.	FSCN1 HCLS1	1.03e-04	3	205	2	32720892
Pubmed	Link protein has greater affinity for versican than aggrecan.	ACAN VCAN	1.03e-04	3	205	2	14724283
Pubmed	Structural basis for kinesin-1:cargo recognition.	PLEKHM2 KLC2	1.03e-04	3	205	2	23519214
Pubmed	Expression analyses and interaction with the anaphase promoting complex protein Apc2 suggest a role for inversin in primary cilia and involvement in the cell cycle.	APC2 ANAPC2	1.03e-04	3	205	2	12471060
Pubmed	Hypoxia-Associated Factor (HAF) Mediates Neurofibromin Ubiquitination and Degradation Leading to Ras-ERK Pathway Activation in Hypoxia.	NF1 SART1	1.03e-04	3	205	2	30705246
Pubmed	Topographical variation in the distributions of versican, aggrecan and perlecan in the foetal human spine reflects their diverse functional roles in spinal development.	ACAN VCAN	1.03e-04	3	205	2	19669783
Pubmed	Expression and purification of functionally active hyaluronan-binding domains from human cartilage link protein, aggrecan and versican: formation of ternary complexes with defined hyaluronan oligosaccharides.	ACAN VCAN	1.03e-04	3	205	2	15590670
Pubmed	Integrative Exome and Transcriptome Analysis of Conjunctival Melanoma and Its Potential Application for Personalized Therapy.	NF1 BRAF	1.03e-04	3	205	2	31647501
Pubmed	Recruitment kinetics of DNA repair proteins Mdc1 and Rad52 but not 53BP1 depend on damage complexity.	RAD52 TP53BP1	1.03e-04	3	205	2	22860035
Pubmed	A complex of Neuroplastin and Plasma Membrane Ca2+ ATPase controls T cell activation.	ATP2B1 ATP2B4	1.03e-04	3	205	2	28827723
Pubmed	The proprotein convertase furin is a pro-oncogenic driver in KRAS and BRAF driven colorectal cancer.	BRAF FURIN	1.03e-04	3	205	2	32139876
Pubmed	G-quadruplexes in the BAP1 promoter positively regulate its expression.	CHD2 CHD7	1.03e-04	3	205	2	29787736
Pubmed	Sp1 and Sp3 transcription factors mediate trichostatin A-induced and basal expression of extracellular superoxide dismutase.	SP3 SOD3	1.03e-04	3	205	2	15451065
Pubmed	Regulation of APC/C activity in oocytes by a Bub1-dependent spindle assembly checkpoint.	ANAPC2 ESPL1	1.03e-04	3	205	2	19249208
Pubmed	P38 MAPK Promotes Migration and Metastatic Activity of BRAF Mutant Melanoma Cells by Inducing Degradation of PMCA4b.	BRAF ATP2B4	1.03e-04	3	205	2	32414111
Pubmed	A novel family of TEA domain-containing transcription factors with distinct spatiotemporal expression patterns.	TEAD4 TEAD3	1.03e-04	3	205	2	8920920
Pubmed	Heterogeneous Presynaptic Distribution of Munc13 Isoforms at Retinal Synapses and Identification of an Unconventional Bipolar Cell Type with Dual Expression of Munc13 Isoforms: A Study Using Munc13-EXFP Knock-in Mice.	UNC13B UNC13C	1.03e-04	3	205	2	33105896
Pubmed	The B-Raf(V600E) inhibitor dabrafenib selectively inhibits RIP3 and alleviates acetaminophen-induced liver injury.	BRAF RIPK3	1.03e-04	3	205	2	24901049
Pubmed	Fibulin-1 is a ligand for the C-type lectin domains of aggrecan and versican.	ACAN VCAN	1.03e-04	3	205	2	10400671
Pubmed	Effect on the Ras/Raf signaling pathway of post-translational modifications of neurofibromin: in silico study of protein modification responsible for regulatory pathways.	NF1 BRAF	1.03e-04	3	205	2	19718661
Pubmed	Transcription factors sp1 and sp3 regulate expression of human extracellular superoxide dismutase in lung fibroblasts.	SP3 SOD3	1.03e-04	3	205	2	18314536
Pubmed	Distinct interaction of versican/PG-M with hyaluronan and link protein.	ACAN VCAN	1.03e-04	3	205	2	12888576
Pubmed	Whole Exome Sequencing Reveals a Monogenic Cause of Disease in ≈43% of 35 Families With Midaortic Syndrome.	NF1 JAG1	1.03e-04	3	205	2	29483232
Pubmed	The Munc13 proteins differentially regulate readily releasable pool dynamics and calcium-dependent recovery at a central synapse.	UNC13B UNC13C	1.03e-04	3	205	2	23658173
Pubmed	Integrative genomics analysis reveals a 21q22.11 locus contributing risk to COVID-19.	IL10RB IFNAR2	1.03e-04	3	205	2	33949668
Pubmed	Germline and somatic NF1 mutations in sporadic and NF1-associated malignant peripheral nerve sheath tumours.	NF1 BRAF	1.03e-04	3	205	2	19142971
Pubmed	In situ hybridization and immunohistochemistry of versican, aggrecan and link protein, and histochemistry of hyaluronan in the developing mouse limb bud cartilage.	ACAN VCAN	1.03e-04	3	205	2	14620382
Interaction	TOP3B interactions	LRWD1 MYO9B C19orf47 OBSCN MAPK8IP3 EIF4ENIF1 PLEKHM2 CLTA NCAPD2 NAV1 DLST DMWD RGL2 LTBP4 SMG6 UNC13B CORO1B ATP13A2 C2CD2 CLDN23 CELSR1 LATS2 MEGF8 SETD5 NISCH FURIN PPP1R15B KANK3 SBF2 TNKS1BP1 ESPL1 TP53BP1 SYMPK	6.67e-06	1470	198	33	int:TOP3B
Interaction	DENND1A interactions	NF1 CLTA NAV1 KIF13B RALGPS2 YWHAH MAP3K21 PCM1	6.98e-06	101	198	8	int:DENND1A
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	ACAN VCAN NCAN	1.14e-06	4	120	3	574
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	PLEKHM2 PLEKHH2 RALGPS2 ASAP3 CERT1 PLEKHG6 SBF2 ARHGAP27	7.00e-05	206	120	8	682
GeneFamily	TEA domain transcription factors	TEAD4 TEAD3	2.60e-04	4	120	2	1183
GeneFamily	UNC13 homologs	UNC13B UNC13C	2.60e-04	4	120	2	836
GeneFamily	Fibronectin type III domain containing	IGFN1 OBSCN MERTK FNDC3B TNN SORL1	6.96e-04	160	120	6	555
GeneFamily	Rho GTPase activating proteins\|BCH domain containing	GDAP2 PRUNE2	8.98e-04	7	120	2	1299
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	OBSCN MCF2 ARHGEF5 ARHGEF35	9.68e-04	66	120	4	722
GeneFamily	Ankyrin repeat domain containing	ANKRD31 TRANK1 EHMT2 ASAP3 ANKRD26 KANK3 POTEA	1.17e-03	242	120	7	403
GeneFamily	ATPases Ca2+ transporting	ATP2B1 ATP2B4	1.53e-03	9	120	2	1209
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	C2CD4C NEDD4L C2CD2	1.74e-03	36	120	3	823
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	ACAN VCAN NCAN	2.53e-03	41	120	3	1298
GeneFamily	WD repeat domain containing\|Protein phosphatase 2 regulatory subunits	PPP2R3B STRN3	4.34e-03	15	120	2	696
GeneFamily	DNA helicases	CHD2 CHD7	5.57e-03	17	120	2	1167
Coexpression	GSE369_PRE_VS_POST_IL6_INJECTION_SOCS3_KO_LIVER_DN	IL10RB MYO9B MEA1 OS9 BAG6 OAS2 CTSA SART1 MEGF8 NISCH	3.73e-06	200	202	10	M5977
Coexpression	ZHOU_INFLAMMATORY_RESPONSE_LIVE_UP	IL12B JAG1 DNHD1 FNDC3B ZCWPW1 NEDD4L KLC2 FRY JRK NCAN SLC39A14 FSCN1 ATP2B1 SOD3	1.21e-05	452	202	14	M18685
Coexpression	EIF4E_DN	FNDC3B NEDD4L ALPK1 CERT1 C2CD2 CLDN23 TP53BP1	1.27e-05	100	202	7	M2790
Coexpression	SCHAEFFER_PROSTATE_DEVELOPMENT_6HR_DN	NAV1 DHX29 SF3B2 SMG6 STRN3 BSDC1 CDC37L1 VANGL2 SART1 FURIN TNKS1BP1 EIF3J FSCN1 SYMPK	1.74e-05	467	202	14	M1347
Coexpression	SCHAEFFER_PROSTATE_DEVELOPMENT_6HR_DN	NAV1 DHX29 SF3B2 SMG6 STRN3 BSDC1 CDC37L1 VANGL2 SART1 FURIN TNKS1BP1 EIF3J FSCN1 SYMPK	2.57e-05	484	202	14	MM999
Coexpression	GSE360_CTRL_VS_M_TUBERCULOSIS_DC_DN	RNF19B ZNF785 AMHR2 WARS1 TOM1 OAS2 VCAN FSCN1 SYMPK	2.66e-05	200	202	9	M5156
Coexpression	GRYDER_PAX3FOXO1_ENHANCERS_IN_TADS	ERICH1 SP3 MYO9B CHD2 HELB CDC123 NAV1 OS9 SF3B2 PARM1 PRUNE2 WARS1 TOM1 CHD7 VANGL2 STC2 SBF2 PRMT3 SSH2 FSCN1 PCM1	3.76e-05	1009	202	21	M157
Coexpression	ZHOU_INFLAMMATORY_RESPONSE_FIMA_UP	IL12B ASIC1 RNF19B DCST2 JAG1 NCAPD2 ZCWPW1 NEDD4L CSF1 TNN NCAN FSCN1 ATP2B1 SOD3	5.25e-05	517	202	14	M7140
ToppCell	COVID-19_Mild-PLT_5\|COVID-19_Mild / Disease Group and Platelet Clusters	RASSF5 SYNE2 NCAPD2 SUCO FNDC3B OAS2 VCAN ATP2B4 SORL1	3.18e-07	195	205	9	bdf9a6ea1bd83c72a834c45f86ce3f4643a9bef3
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	HEBP2 KANSL2 RNF141 JAG1 LTBP4 C1orf226 TMEM44 SLC39A14	1.44e-06	173	205	8	4968712af1cca8c932abd3323631d7dcaffd4a66
ToppCell	droplet-Liver-Hepatocytes-21m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RTN2 JAG1 LTBP4 TEAD4 SLC39A12 TMEM44 KANK3 ATP2B4	2.37e-06	185	205	8	efcfbf5a48b3ea9a425183e5c2eec6a9585415a0
ToppCell	droplet-Liver-Hepatocytes-21m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RTN2 JAG1 LTBP4 TEAD4 SLC39A12 TMEM44 KANK3 ATP2B4	2.37e-06	185	205	8	642088ace9230d38b0579853c54ff4dd8b5d5df4
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	CHD2 INO80D NF1 BRAF SYNE2 SUCO SMG6 TP53BP1	2.68e-06	188	205	8	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	nucseq-Immune-Immune_Myeloid-pMON-pMON\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MYO9B HEATR3 WARS1 IFNAR2 SBF2 SNX18 SSH2 ARHGAP27	3.38e-06	194	205	8	e237384b02be460d44eeada3026a5691c66f6fc1
ToppCell	nucseq-Immune-Immune_Myeloid-pMON\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MYO9B HEATR3 WARS1 IFNAR2 SBF2 SNX18 SSH2 ARHGAP27	3.38e-06	194	205	8	0bc83ae79873a5e473e6e1e3111924cd003986a1
ToppCell	Fibroblasts-Pericytes\|Fibroblasts / lung cells shred on cell class, cell subclass, sample id	ACAN JAG1 SYNE2 PARM1 PRUNE2 FRY SOD3 CCDC107	3.51e-06	195	205	8	c2ebc0b33bda9b35b9ef26d69e5d2c6acfdb6ff1
ToppCell	H1299-infected-SARSCoV2\|infected / Cell line, Condition and Strain	CHD2 KNOP1 SMG6 ANKRD26 AKAP9 NISCH CEP295 EIF3J	3.78e-06	197	205	8	0fa3e4cf93e77d78b1f97b906c5b13ca741ae17e
ToppCell	TCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Papillary_Muscle_Invasive_Urothelial_Carcinoma\|TCGA-Bladder / Sample_Type by Project: Shred V9	HEBP2 LRIT3 RGL2 CRTAC1 CORO1B FER1L4 ARHGAP27	8.77e-06	158	205	7	dc559503bab3ec1b9ea54ef2e896d1be33e5344c
ToppCell	343B-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	PPP2R3B RTN2 RNF25 SHQ1 FRY KANK3 SBF2	1.07e-05	163	205	7	0ab043b68e8739adcedda01165a3758cd0d22728
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PEX11A MAPK8IP3 CNGB1 KIF13B C2orf81 CELSR1 C1orf226	1.47e-05	171	205	7	1854a777d9eb9d3fc3ed3632332a6f89ce8131da
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	CHD2 HELB BRAF SYNE2 TEAD4 AKAP9 PCM1	1.47e-05	171	205	7	2e9a20f8980b78325c52065a9c14ab3656267c05
ToppCell	droplet-Liver-Npc-21m-Epithelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PEX11A KLC2 MEGF8 TP53BP1 SOD3	1.91e-05	71	205	5	cf4c8715c2bd77fc86e45cc01bcc7aa6044e091d
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Macroglial-Oligodendrocyte_progenitor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ASIC1 ETV4 RTN2 ACAN PRUNE2 VCAN NCAN	2.04e-05	180	205	7	907cd510fd2e21532ce04ba687e8894f7af71f27
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Macroglial-oligodendrocyte_precursor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ASIC1 ETV4 RTN2 ACAN PRUNE2 VCAN NCAN	2.04e-05	180	205	7	fa819df81fca95c2cc602fede635cb03e3f35fad
ToppCell	COVID-19-kidney-CD-IC-B\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ASXL1 HMX2 VWA5B1 KIF13B NEDD4L RALGPS2 UNC13C	2.19e-05	182	205	7	ee6a8c356bbbdae55e4ea858337e079491f9f4aa
ToppCell	facs-Brain_Non-Myeloid-Cortex_-18m-Macroglial-Oligodendrocyte_progenitor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ASIC1 ETV4 ADCYAP1R1 ACAN PRUNE2 VCAN NCAN	2.35e-05	184	205	7	278a7ed764c326450cb70e69ed2175980eaf5fe0
ToppCell	facs-Brain_Non-Myeloid-Cortex_-18m-Macroglial-oligodendrocyte_precursor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ASIC1 ETV4 ADCYAP1R1 ACAN PRUNE2 VCAN NCAN	2.35e-05	184	205	7	8d86e125257ff1d3af8d90577a8b3f0321eca21c
ToppCell	droplet-Liver-Hepatocytes-21m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RTN2 JAG1 DMWD LTBP4 RAD52 TMEM44 KANK3	2.43e-05	185	205	7	60206c7322b4ddb2010040aac70561df842c9843
ToppCell	droplet-Liver-LIVER_HEP-30m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NAV1 LTBP4 WARS1 ARHGEF5 TEAD4 SLC39A12 CSF1	2.43e-05	185	205	7	bdd2e6cb20294b39a9d856004bf57ba69cf877e2
ToppCell	droplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GREB1L LTBP4 PARM1 PRUNE2 STC2 TNKS1BP1 ATP2B4	2.52e-05	186	205	7	c116cc9f41971622264434ebe29d18e719b0ae19
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c03-CD27-AIM2\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ABRA PARM1 RALGPS2 CHD7 YWHAH CELSR1 ATP2B1	2.52e-05	186	205	7	55b239834b96b1f7787ec77a7d19796d617bbbf0
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	CHD2 HELB BRAF SYNE2 PPP1R15B PCM1 SORL1	3.09e-05	192	205	7	47646d7e4990be85072987f92bf18d52f8da752e
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-Pericytes\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	IGFN1 ACAN JAG1 PARM1 STC2 INS-IGF2 SOD3	3.19e-05	193	205	7	47d189bac0ef4df2f5c6dd987e46aca85bd7e2af
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature4_(1)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	ASXL1 HELB BSDC1 TEAD4 CSF1 LATS2 PPP1R15B	3.19e-05	193	205	7	dbf0fe496254320c894568c31e5f9ce63707d1b5
ToppCell	Control-Myeloid-ncMonocyte\|World / Disease state, Lineage and Cell class	MYO9B HEATR3 AMPH ZCWPW1 WARS1 IFNAR2 SNX18	3.41e-05	195	205	7	b4444b67a709e82b8e2ee510924c3152cb88b051
ToppCell	5'-GW_trimst-2-SmallIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TAC4 ACAN JAG1 AMPH FRY STC2 SOD3	3.64e-05	197	205	7	cc494a656db868bb489238a5becc31bc8518f3cc
ToppCell	Sepsis-ICU-SEP-Lymphocyte-T/NK-Treg\|ICU-SEP / Disease, condition lineage and cell class	ANKRD31 OBSCN NAP1L4 SYNE2 ARHGEF5 CORO1B ARHGEF35	3.64e-05	197	205	7	c3ee2d522fbfe67069ddba2d1abfc4f5ca230c26
ToppCell	Control-Control-Lymphocyte-T/NK-NK_activated\|Control / Disease, condition lineage and cell class	MCF2 TRANK1 SYNE2 OAS2 MEGF8 TNKS1BP1 ATP2B4	3.75e-05	198	205	7	76d5fe4e5bbe6c73a6ca409b80b5c3924e07cab7
ToppCell	mild-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	CHD2 HELB BRAF SYNE2 SMG6 AKAP9 PCM1	3.88e-05	199	205	7	f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell	mild-CD8+_T_naive\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ANKRD31 LDLRAP1 NAP1L4 HELB ANKRD26 CDC37L1 PCM1	4.00e-05	200	205	7	c825320599a61a4c629d736f5c0fd6f1f405540a
ToppCell	COVID-19-COVID-19_Severe-Lymphocyte-T/NK-CD4+_T_activated\|COVID-19_Severe / Disease, condition lineage and cell class	LDLRAP1 UBASH3A HELB TRANK1 SYNE2 ANKRD26 OAS2	4.00e-05	200	205	7	deeed668b129e66156b5f6abe1a07a9bf842a14d
Drug	Pancuronium bromide [15500-66-0]; Down 200; 5.4uM; MCF7; HT_HG-U133A	INO80D NF1 AJAP1 SYNE2 MERTK RAD52 STRN3 ASAP3 BSDC1 APBA3	8.87e-06	195	199	10	4393_DN
Drug	Pepstatin A [26305-03-3]; Down 200; 5.8uM; MCF7; HT_HG-U133A	RNF19B GREB1L RAD52 RALGPS2 APBA3 OAS2 ALPK1 PLEKHG6 FSCN1 PCM1	1.01e-05	198	199	10	3264_DN
Drug	Indoprofen [31842-01-0]; Down 200; 14.2uM; MCF7; HT_HG-U133A	INO80D MAPK8IP3 SMG6 RAD52 ZCWPW1 ASAP3 APBA3 CSF1 FSCN1 SYMPK	1.06e-05	199	199	10	3345_DN
Drug	Chicago sky blue 6B [2610-05-1]; Down 200; 4uM; MCF7; HT_HG-U133A	LDLRAP1 MYO9B RAD52 KIF13B TOM1 ANKRD26 APBA3 OAS2 CSF1 FSCN1	1.06e-05	199	199	10	3266_DN
Drug	tamoxifen citrate; Up 200; 1uM; MCF7; HG-U133A	MBD1 NAP1L4 SYNE2 MERTK TOM1 ALPK1 TEAD4 NCAN ATP2B4 TP53BP1	1.06e-05	199	199	10	143_UP
Drug	4'-Aagb	ABRA BLOC1S4 ACAN JAG1 SYMPK	1.68e-05	37	199	5	CID000001718
Drug	LY294002; Up 200; 10uM; MCF7; HG-U133A	LDLRAP1 RTN2 MAPK8IP3 GREB1L NF1 SHC2 RNF141 LTBP4 RALGPS2	5.49e-05	194	199	9	258_UP
Drug	Hesperetin [520-33-2]; Down 200; 13.2uM; PC3; HG-U133A	ASXL1 KNOP1 NF1 PLEKHM2 KIF13B KLC2 STC2 FURIN PCM1	5.49e-05	194	199	9	1947_DN
Drug	Desipramine hydrochloride [58-28-6]; Up 200; 13.2uM; MCF7; HT_HG-U133A	IL12B ARMCX2 GREB1L NF1 SHC2 DMWD SMG6 NEDD4L ASAP3	5.72e-05	195	199	9	3212_UP
Drug	Betulinic acid [472-15-1]; Down 200; 8.8uM; MCF7; HT_HG-U133A	ASIC1 SPTA1 RNF19B GREB1L RAD52 ANKRD26 KLC2 OAS2 ALPK1	5.72e-05	195	199	9	4181_DN
Drug	Dihydrostreptomycin sulfate [5490-27-7]; Down 200; 2.8uM; PC3; HT_HG-U133A	ASIC1 NF1 BRAF RAD52 TOM1 ASAP3 CSF1 PCM1 SYMPK	5.95e-05	196	199	9	5751_DN
Drug	benserazide hydrochloride; Down 200; 10uM; SKMEL5; HG-U133A	ASXL1 MAPK8IP3 NF1 ACAN JAG1 ANGEL1 KLC2 EBAG9 PRMT3	5.95e-05	196	199	9	631_DN
Drug	Morantel tartrate [26155-31-7]; Up 200; 10.8uM; MCF7; HT_HG-U133A	MAPK8IP3 NF1 AJAP1 ASAP3 ANKRD26 ALPK1 AKAP9 FSCN1 SYMPK	5.95e-05	196	199	9	7010_UP
Drug	Myricetin [529-44-2]; Down 200; 12.6uM; MCF7; HT_HG-U133A	MBD1 GREB1L RAD52 RALGPS2 ANKRD26 OAS2 IFNAR2 PCM1 SORL1	6.19e-05	197	199	9	3270_DN
Drug	Arcaine sulfate [14923-17-2]; Down 200; 14.8uM; PC3; HT_HG-U133A	ASIC1 MBD1 INO80D MAPK8IP3 NF1 ACAN ZCWPW1 ASAP3 PLEKHG6	6.19e-05	197	199	9	6629_DN
Drug	Doxepin hydrochloride [1229-29-4]; Up 200; 12.6uM; MCF7; HT_HG-U133A	MBD1 RNF19B RTN2 NF1 KIF13B APBA3 ATP2B1 ATP2B4 SYMPK	6.19e-05	197	199	9	7415_UP
Drug	Pirenperone [ 75444-65-4]; Up 200; 10.2uM; MCF7; HT_HG-U133A	LDLRAP1 INO80D TRANK1 AJAP1 RALGPS2 ASAP3 CRTAC1 CSF1 SOD3	6.19e-05	197	199	9	3316_UP
Drug	Lysergol [602-85-7]; Down 200; 15.8uM; PC3; HT_HG-U133A	INO80D MAPK8IP3 KNOP1 DMWD SMG6 ASAP3 ALPK1 AKAP9 FURIN	6.19e-05	197	199	9	6621_DN
Drug	Zidovudine, AZT [30516-87-1]; Down 200; 15uM; HL60; HG-U133A	ASXL1 NF1 MCAT HEATR3 UNC13B TMEM115 APBA3 CERT1 ATP2B4	6.43e-05	198	199	9	1595_DN
Drug	Guanabenz acetate [23256-50-0]; Up 200; 13.8uM; MCF7; HT_HG-U133A	SHC2 PER3 JAG1 NEDD4L CSF1 VCAN ATP2B4 PCM1 SYMPK	6.43e-05	198	199	9	1544_UP
Drug	estradiol, USP; Down 200; 0.01uM; HL60; HG-U133A	LDLRAP1 RNF19B BRAF ACAN ANAPC2 ASAP3 KLC2 CERT1 SZRD1	6.43e-05	198	199	9	387_DN
Drug	Megestrol acetate [595-33-5]; Down 200; 10.4uM; MCF7; HT_HG-U133A	RNF19B INO80D MAPK8IP3 NF1 MERTK LTBP4 TOM1 RNF25 SYMPK	6.43e-05	198	199	9	6468_DN
Drug	Oxaprozin [21256-18-8]; Down 200; 13.6uM; MCF7; HT_HG-U133A	RTN2 NF1 PER3 BRAF ASAP3 CSF1 FSCN1 PCM1 SYMPK	6.69e-05	199	199	9	4352_DN
Drug	Tetrandrine [518-34-3]; Down 200; 6.4uM; PC3; HT_HG-U133A	MAPK8IP3 KNOP1 BSDC1 APBA3 ALPK1 ATP13A2 CDC37L1 CSF1 FURIN	6.69e-05	199	199	9	5821_DN
Drug	Diethylcarbamazine citrate [1642-54-2]; Up 200; 10.2uM; PC3; HT_HG-U133A	IL12B UBASH3A NACAD NF1 JAG1 RAD52 AMPH ZCWPW1 MUC5AC	6.69e-05	199	199	9	5066_UP
Drug	clozapine; Down 200; 10uM; MCF7; HG-U133A	LDLRAP1 PEX11A GREB1L NF1 LTBP4 SZRD1 PCM1 SOD3 SYMPK	6.95e-05	200	199	9	416_DN
Drug	HA-1077 dihydrochloride; Up 200; 10uM; PC3; HG-U133A	ASIC1 KNOP1 ACAN ANAPC2 LTBP4 PARM1 RNF25 ASAP3 ALPK1	6.95e-05	200	199	9	436_UP
Drug	caloxin 1b1	ATP2B1 ATP2B4	7.60e-05	2	199	2	ctd:C510327
Disease	apolipoprotein B measurement	ANKRD31 LDLRAP1 TAC4 NF1 SYNE2 PLEKHH2 DMWD KIF13B AMHR2 CERT1 PARP10 FER1L4 NISCH NCAN SYMPK	3.82e-05	663	195	15	EFO_0004615
Disease	sexual dimorphism measurement	ANKRD31 ASIC1 MYO9B TRANK1 NF1 ACAN FNIP1 BSN SUCO FNDC3B RIPK3 TEAD3 CERT1 ATP13A2 SART1 PARP10 FER1L4 KANK3 INS-IGF2 TP53BP1	4.83e-05	1106	195	20	EFO_0021796
Disease	eosinophil count	NAP1L4 DCST2 UBASH3A NACAD ZNF785 JAG1 FNIP1 DLST LTBP4 OAS2 ATG14 ZKSCAN2 CHD7 IFNAR2 VANGL2 CELSR1 AKAP9 SBF2 NUP133 TNKS1BP1 POTEA MUC5AC TP53BP1 SYMPK	5.12e-05	1488	195	24	EFO_0004842
Disease	neuroimaging measurement	MAPK8IP3 NF1 JAG1 DLST SMG6 STRN3 RALGPS2 CHD7 ATP13A2 VANGL2 SLC39A12 CELSR1 FURIN VCAN SSH2 ARHGAP27 SLC39A14 INS-IGF2 SZRD1	9.42e-05	1069	195	19	EFO_0004346
Disease	total cholesterol measurement, hematocrit, stroke, ventricular rate measurement, body mass index, atrial fibrillation, high density lipoprotein cholesterol measurement, coronary artery disease, diastolic blood pressure, triglyceride measurement, systolic blood pressure, heart failure, diabetes mellitus, glucose measurement, mortality, cancer	ANKRD31 ANKRD26 TEAD4 CERT1 ATP2B1	9.55e-05	69	195	5	EFO_0000275, EFO_0000400, EFO_0000712, EFO_0001645, EFO_0003144, EFO_0004340, EFO_0004348, EFO_0004352, EFO_0004468, EFO_0004530, EFO_0004574, EFO_0004612, EFO_0006335, EFO_0006336, EFO_0007928, MONDO_0004992
Disease	free cholesterol measurement, very low density lipoprotein cholesterol measurement	ASAP3 CRTAC1 CERT1 PRKAG3 KANK3 NCAN EIF3J TP53BP1	9.76e-05	215	195	8	EFO_0008317, EFO_0008591
Disease	Malignant neoplasm of breast	APC2 OBSCN ETV4 NF1 PER3 BRAF JAG1 SYNE2 MAGEC2 FNDC3B WARS1 SLC39A12 CSF1 AKAP9 STC2 NISCH NUP133 TP53BP1 SORL1	1.00e-04	1074	195	19	C0006142
Disease	testosterone measurement	MYO9B ZNF785 NF1 PER3 SYNE2 CASC3 ZCWPW1 WARS1 ZAN RALGPS2 CRTAC1 CHD7 C2CD2 CDC37L1 IFNAR2 PRKAG3 NISCH SBF2 TNKS1BP1 ATP2B4 INS-IGF2	1.16e-04	1275	195	21	EFO_0004908
Disease	triglyceride measurement, very low density lipoprotein cholesterol measurement	SYNE2 CRTAC1 CERT1 PRKAG3 KANK3 NCAN EIF3J TP53BP1	1.29e-04	224	195	8	EFO_0004530, EFO_0008317
Disease	–	IL10RB IFNAR2	1.30e-04	3	195	2	610424
Disease	Hepatitis B virus, susceptibility to	IL10RB IFNAR2	1.30e-04	3	195	2	cv:C1864880
Disease	very low density lipoprotein cholesterol measurement, phospholipid measurement	ASAP3 CRTAC1 CERT1 PRKAG3 KANK3 NCAN EIF3J TP53BP1	1.51e-04	229	195	8	EFO_0004639, EFO_0008317
Disease	fatty acid measurement	ANKRD31 GREB1L AMPH ASAP3 CRTAC1 CERT1 PRKAG3 KANK3 NCAN EIF3J TP53BP1	1.66e-04	436	195	11	EFO_0005110
Disease	netrin-1 measurement	MBD1 PCM1	2.58e-04	4	195	2	EFO_0022009
Disease	Melanocytic nevus	NF1 BRAF	2.58e-04	4	195	2	C0027962
Disease	very low density lipoprotein cholesterol measurement	ANKRD31 CRTAC1 CERT1 PRKAG3 KANK3 NCAN EIF3J TP53BP1	3.55e-04	260	195	8	EFO_0008317
Disease	obsolete_interleukin 12 receptor subunit beta-1 measurement	IL10RB IL12B	4.29e-04	5	195	2	EFO_0008170
Disease	Disorder of eye	LRIT3 GPR179 MERTK CNGB1 ATP13A2 VCAN MFSD8	5.47e-04	212	195	7	C0015397
Disease	Cerebral Astrocytoma	NF1 BRAF LATS2	5.87e-04	25	195	3	C0750935
Disease	Intracranial Astrocytoma	NF1 BRAF LATS2	5.87e-04	25	195	3	C0750936
Disease	Astrocytoma	NF1 BRAF LATS2	5.87e-04	25	195	3	C0004114
Disease	Grade I Astrocytoma	NF1 BRAF LATS2	5.87e-04	25	195	3	C1704230
Disease	Subependymal Giant Cell Astrocytoma	NF1 BRAF LATS2	5.87e-04	25	195	3	C0205768
Disease	Mixed oligoastrocytoma	NF1 BRAF LATS2	5.87e-04	25	195	3	C0547065
Disease	Pilocytic Astrocytoma	NF1 BRAF LATS2	5.87e-04	25	195	3	C0334583
Disease	Juvenile Pilocytic Astrocytoma	NF1 BRAF LATS2	5.87e-04	25	195	3	C0280783
Disease	Diffuse Astrocytoma	NF1 BRAF LATS2	5.87e-04	25	195	3	C0280785
Disease	Childhood Cerebral Astrocytoma	NF1 BRAF LATS2	5.87e-04	25	195	3	C0338070
Disease	stearoyl sphingomyelin (d18:1/18:0) measurement	SYNE2 KANK3	6.40e-04	6	195	2	EFO_0800611
Disease	Hailey-Hailey disease (implicated_via_orthology)	ATP2B1 ATP2B4	6.40e-04	6	195	2	DOID:0050429 (implicated_via_orthology)
Disease	Gemistocytic astrocytoma	NF1 BRAF LATS2	6.61e-04	26	195	3	C0334581
Disease	Protoplasmic astrocytoma	NF1 BRAF LATS2	6.61e-04	26	195	3	C0334580
Disease	Fibrillary Astrocytoma	NF1 BRAF LATS2	6.61e-04	26	195	3	C0334582
Disease	very low density lipoprotein cholesterol measurement, lipid measurement	CRTAC1 CERT1 PRKAG3 KANK3 NCAN EIF3J TP53BP1	6.80e-04	220	195	7	EFO_0004529, EFO_0008317
Disease	Anaplastic astrocytoma	NF1 BRAF LATS2	7.40e-04	27	195	3	C0334579
Disease	estradiol measurement	C2CD4C HELB EHMT2 NAV1 CELSR1	8.36e-04	110	195	5	EFO_0004697
Disease	triglyceride measurement, low density lipoprotein cholesterol measurement	SYNE2 CRTAC1 PRKAG3 KANK3 EIF3J TP53BP1	8.53e-04	166	195	6	EFO_0004530, EFO_0004611
Disease	triglyceride measurement, intermediate density lipoprotein measurement	SYNE2 CRTAC1 KANK3 EIF3J TP53BP1	8.71e-04	111	195	5	EFO_0004530, EFO_0008595
Disease	CHARGE syndrome (implicated_via_orthology)	CHD2 CHD7	8.93e-04	7	195	2	DOID:0050834 (implicated_via_orthology)
Disease	Myeloid Leukemia, Chronic	ASXL1 PER3 BRAF	9.15e-04	29	195	3	C0023473
Disease	pulse pressure measurement	MBD1 CHD2 FAM186B TRANK1 PLEKHM2 CDC123 JAG1 NAV1 BAG6 SMG6 FNDC3B RALGPS2 CRTAC1 CLDN23 LATS2 MEGF8 FURIN SBF2 ATP2B1 PCM1	9.58e-04	1392	195	20	EFO_0005763
Disease	common bile duct neoplasm (is_marker_for)	FSCN1 MUC5AC	1.19e-03	8	195	2	DOID:4608 (is_marker_for)
Disease	NEURAL TUBE DEFECTS, SUSCEPTIBILITY TO	VANGL2 CELSR1	1.19e-03	8	195	2	C3891448
Disease	cortical surface area measurement	MYO9B JAG1 NAV1 SMG6 AMHR2 STRN3 ZAN RALGPS2 CRTAC1 CHD7 CERT1 ATP13A2 CLDN23 VANGL2 CELSR1 VCAN SSH2 ARHGAP27 INS-IGF2	1.56e-03	1345	195	19	EFO_0010736
Disease	COVID-19 symptoms measurement	TAC4 IFNAR2 MUC5AC	1.59e-03	35	195	3	EFO_0600019
Disease	reticulocyte count	MYO9B SPTA1 TAC4 INO80D GREB1L RASSF5 JAG1 SYNE2 BSN SMG6 RAD52 FNDC3B NISCH KANK3 ATP2B1 ATP2B4	1.64e-03	1045	195	16	EFO_0007986
Disease	diastolic blood pressure, systolic blood pressure	MBD1 CDC123 ACAN JAG1 NAV1 UNC13B FNDC3B RALGPS2 SLC39A12 CSF1 ATP2B4 PCM1	1.76e-03	670	195	12	EFO_0006335, EFO_0006336
Disease	reticulocyte measurement	MYO9B SPTA1 TAC4 RASSF5 JAG1 SYNE2 BSN SMG6 RAD52 FNDC3B CDC37L1 NISCH KANK3 SBF2 ATP2B1 ATP2B4	1.77e-03	1053	195	16	EFO_0010700
Disease	Glioblastoma	NF1 JAG1 LTBP4 TP53BP1	1.89e-03	79	195	4	C0017636
Disease	Abnormality of nervous system morphology	APC2 MAPK8IP3	1.89e-03	10	195	2	C4022810
Disease	squamous cell carcinoma, esophageal carcinoma	HEATR3 SMG6	1.89e-03	10	195	2	EFO_0000707, EFO_0002916
Disease	very low density lipoprotein particle size measurement	CRTAC1 PRKAG3 NCAN EIF3J TP53BP1	1.94e-03	133	195	5	EFO_0008594
Disease	Antihypertensive use measurement	MYO9B SMG6 NEDD4L FURIN SBF2 ATP2B1 ATP2B4	1.99e-03	265	195	7	EFO_0009927
Disease	autosomal dominant nonsyndromic deafness (is_implicated_in)	GREB1L ELMOD3	2.30e-03	11	195	2	DOID:0050564 (is_implicated_in)
Disease	Giant Cell Glioblastoma	NF1 JAG1 LTBP4 TP53BP1	2.36e-03	84	195	4	C0334588
Disease	Night blindness, congenital stationary, type 1	LRIT3 GPR179	2.75e-03	12	195	2	C3501847
Disease	Night Blindness, Congenital Stationary, Type 1A	LRIT3 GPR179	2.75e-03	12	195	2	C3495587
Disease	NIGHT BLINDNESS, CONGENITAL STATIONARY, TYPE 2B (disorder)	LRIT3 GPR179	2.75e-03	12	195	2	C1864877
Disease	NIGHT BLINDNESS, CONGENITAL STATIONARY, TYPE 1B	LRIT3 GPR179	2.75e-03	12	195	2	C1850362
Disease	X-Linked Csnb	LRIT3 GPR179	2.75e-03	12	195	2	C3711543
Disease	NIGHT BLINDNESS, CONGENITAL STATIONARY, TYPE 2A	LRIT3 GPR179	2.75e-03	12	195	2	C1848172
Disease	insulin sensitivity measurement, glucose homeostasis measurement	SETD5 UNC13C MFSD8	2.89e-03	43	195	3	EFO_0004471, EFO_0006896
Disease	neuroimaging measurement, brain volume measurement	NF1 JAG1 STRN3 ATP13A2 SLC39A12 DTWD2 VCAN	3.04e-03	286	195	7	EFO_0004346, EFO_0006930
Disease	cortical thickness	MAPK8IP3 JAG1 NAV1 SMG6 STRN3 RALGPS2 CHD7 ATP13A2 VANGL2 CELSR1 SETD5 FURIN VCAN EBAG9 SSH2 INS-IGF2	3.07e-03	1113	195	16	EFO_0004840
Disease	Cone-rod synaptic disorder, congenital nonprogressive	LRIT3 GPR179	3.23e-03	13	195	2	C4041558
Disease	triglycerides:total lipids ratio, low density lipoprotein cholesterol measurement	ANKRD31 SYNE2 PRKAG3 EIF3J TP53BP1	3.27e-03	150	195	5	EFO_0004611, EFO_0020947
Disease	Malignant neoplasm of salivary gland	JAG1 VCAN ESPL1	3.29e-03	45	195	3	C0220636
Disease	FEV/FEC ratio	ASXL1 BLOC1S4 RASSF5 CDC123 ACAN SYNE2 NAV1 LTBP4 SMG6 FNDC3B ZKSCAN2 TEAD4 ATP13A2 SBF2 SSH2 ATP2B1 SORL1	3.37e-03	1228	195	17	EFO_0004713
Disease	very low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio	ANKRD31 SYNE2 CERT1 PRKAG3 EIF3J TP53BP1	3.69e-03	222	195	6	EFO_0008317, EFO_0020943
Disease	hemolysis	MYO9B SPTA1 TAC4	3.72e-03	47	195	3	EFO_0009473
Disease	Salivary Gland Neoplasms	JAG1 VCAN ESPL1	3.72e-03	47	195	3	C0036095
Disease	Manganese Poisoning	ATP13A2 SLC39A14	3.75e-03	14	195	2	C0677050
Disease	total cholesterol measurement, very low density lipoprotein cholesterol measurement	CRTAC1 CERT1 KANK3 NCAN EIF3J TP53BP1	3.86e-03	224	195	6	EFO_0004574, EFO_0008317
Disease	smoking status measurement, systolic blood pressure	AJAP1 EHMT2 CRTAC1 CLDN23 ATP2B1	3.87e-03	156	195	5	EFO_0006335, EFO_0006527
Disease	glucose measurement	EHMT2 CDC123 PLEKHH2 BSN WARS1 ZAN MEGF8 INS-IGF2	3.93e-03	380	195	8	EFO_0004468
Disease	cholesteryl ester measurement, very low density lipoprotein cholesterol measurement	CRTAC1 CERT1 KANK3 NCAN EIF3J TP53BP1	3.94e-03	225	195	6	EFO_0008317, EFO_0010351
Disease	Proteinuria	SMG6 UNC13C	4.31e-03	15	195	2	HP_0000093
Disease	RASopathy	NF1 BRAF	4.31e-03	15	195	2	cv:C5555857
Disease	total cholesterol measurement, diastolic blood pressure, triglyceride measurement, systolic blood pressure, hematocrit, ventricular rate measurement, glucose measurement, body mass index, high density lipoprotein cholesterol measurement	ANKRD31 CERT1 ATP2B1	4.69e-03	51	195	3	EFO_0004340, EFO_0004348, EFO_0004468, EFO_0004530, EFO_0004574, EFO_0004612, EFO_0006335, EFO_0006336, EFO_0007928
Disease	cholesteryl ester measurement, high density lipoprotein cholesterol measurement	PRKAG3 CSF1 NISCH SBF2 NCAN EIF3J TP53BP1	4.88e-03	312	195	7	EFO_0004612, EFO_0010351
Disease	cholesteryl esters:total lipids ratio, intermediate density lipoprotein measurement	SYNE2 CERT1 PRKAG3 TP53BP1	4.92e-03	103	195	4	EFO_0008595, EFO_0020944
Disease	free cholesterol measurement, high density lipoprotein cholesterol measurement	ASAP3 CERT1 PRKAG3 CSF1 SBF2 EIF3J TP53BP1	5.13e-03	315	195	7	EFO_0004612, EFO_0008591
Disease	total cholesterol measurement, high density lipoprotein cholesterol measurement	PRKAG3 CSF1 NISCH SBF2 NCAN EIF3J TP53BP1	5.13e-03	315	195	7	EFO_0004574, EFO_0004612
Disease	HbA1c measurement	MYO9B SPTA1 TAC4 CDC123 PLEKHH2 BSN FNDC3B WARS1 SBF2 ATP2B4 INS-IGF2	5.49e-03	675	195	11	EFO_0004541
Disease	Moyamoya Disease	NF1 JAG1	5.54e-03	17	195	2	C0026654
Disease	Night blindness, congenital stationary	LRIT3 GPR179	5.54e-03	17	195	2	C0339535
Disease	sex interaction measurement, ulcerative colitis	EHMT2 OS9	5.54e-03	17	195	2	EFO_0000729, EFO_0008343
Disease	peak expiratory flow	CDC123 ACAN LTBP4 FNDC3B ZKSCAN2 ATP13A2 FRY SSH2 SORL1	6.11e-03	498	195	9	EFO_0009718
Disease	chronic obstructive pulmonary disease	MBD1 EHMT2 CDC123 NAV1 DMWD LTBP4 SMG6 FNDC3B RALGPS2 SSH2 PCM1	6.30e-03	688	195	11	EFO_0000341
Disease	Glioblastoma Multiforme	NF1 JAG1 LTBP4 TP53BP1	6.39e-03	111	195	4	C1621958

Protein segments in the cluster

Peptide	Gene	Start	Entry
GDERDDNWGETTTVV	VANGL2	61	Q9ULK5
FLDTDDEVSPTSWGD	SMG6	476	Q86US8
ASEEDPTWAGEEEGA	ERICH1	301	Q86X53
SSDDWEIPDGQITVG	BRAF	446	P15056
SDGEDHSIQQVSEPW	AKAP9	2966	Q99996
SWVISTEPGSDSEED	ASAP3	691	Q8TDY4
QEEWEAVDTIQPETG	ELMOD3	76	Q96FG2
TGQDSEDDSGEPEDW	ANAPC2	466	Q9UJX6
EGSAENWADAEVGPS	CXorf49;	126	A8MYA2
TTADEIELEGATQWP	VCAN	2961	P13611
LGATPETDEDLAWDS	C19orf47	266	Q8N9M1
AEQSISEEPGWEEEE	BSDC1	211	Q9NW68
DDVELATEFPATEAW	PRKAG3	131	Q9UGI9
TLWTSDQQDEEAGEG	YWHAH	231	Q04917
AEEAEPQGAAWSGDS	BLOC1S4	16	Q9NUP1
SRDEQDGASAETEPW	BAG6	996	P46379
DEETDLGTDWENLPS	ATG14	426	Q6ZNE5
SDLGSEEEEVEFWPG	ARHGEF5	141	Q12774
TETEFIAWGPTGDEE	AJAP1	176	Q9UKB5
IAWGPTGDEEALESN	AJAP1	181	Q9UKB5
DEDSDSPEWVEGASA	APBA3	146	O96018
SPEWVEGASAEQEGS	APBA3	151	O96018
SDLGSEEEEVEFWPG	ARHGEF35	141	A5YM69
DTAGPEAALEAEEWV	CORO1B	366	Q9BR76
GTSDASVEDPVVEWQ	BRWD3	831	Q6RI45
PGSLEEWETVVGDDF	EHMT2	256	Q96KQ7
AGWPDQSLAESDSED	CELSR1	2861	Q9NYQ6
VTSESQEEPWEEEFG	FAM186B	471	Q8IYM0
TDDWESSPNTQTQVE	DNHD1	1406	Q96M86
GQEEDIESPWDSESI	ANKRD26	411	Q9UPS8
NSEDPEESWENLVSD	DHX29	516	Q7Z478
EADDDSADGLWELPV	DTWD2	46	Q8NBA8
SAEDWLSEEATDADP	C2CD4C	116	Q8TF44
LEGADSSEADVWIPE	CHD7	1761	Q9P2D1
TDEETEAQTGEGSWP	DMWD	636	Q09019
FLAEVPDSEEGESGW	ARMCX2	331	Q7L311
PDSEEGESGWTDTES	ARMCX2	336	Q7L311
EPEWDNENDIVTGLT	ATP2B1	661	P20020
ATTPEDENEAQAGWI	ATP2B4	136	P23634
DDTEPSWDNENEILT	ATP2B4	646	P23634
SGTTSWESDDEEQGP	ASXL1	791	Q8IXJ9
SPSWVDPEGETAEST	ALPK1	781	Q96QP1
EAELGNTPTSDELWA	AMHR2	441	Q16671
VVPSDSEADQDAGWL	AMPH	651	P49418
QETWLAEAQVPDSDE	ETV4	61	P43268
TSWDEDAPTSVKIEG	EBAG9	61	O00559
DILVAEETAGEPWED	PPP2R3B	511	Q9Y5P8
ENETGEVEWDAFSIP	RASSF5	361	Q8WWW0
EDNSEKWAVTPDAGD	RAD52	326	P43351
SSSAPVLEEGDTDPW	SLC34A3	31	Q8N130
DTPGSREWDILETEE	MFSD8	16	Q8NHS3
EPAWEEGATSQTVAT	LRWD1	301	Q9UFC0
DWDKPDSSGTEQDDL	LDLRAP1	291	Q5SW96
SWNSSGSEEDPETES	CERT1	6	Q9Y5P4
QAPDWDSDETVIEGS	ANKRD31	6	Q8N7Z5
VDVDTLPSWGDSCQD	GDAP2	11	Q9NXN4
DNWSSSDGKDDPIEV	NUP133	1081	Q8WUM0
TGDVEPTDAESEWHS	NAP1L4	111	Q99733
PTDAESEWHSENEEE	NAP1L4	116	Q99733
NVDNDSPTSVELEDW	MAGEC2	11	Q9UBF1
DEWSDVQDIIDSTPE	MAPK8IP3	336	Q9UPT6
LNGGSEEWEDLTSAP	MERTK	931	Q12866
WEVTESETRQPDSGN	GPR179	1246	Q6PRD1
DEESPWNDASEGSTK	LATS2	1006	Q9NRM7
PGWNEDDDVSVSDES	SBF2	1076	Q86WG5
SDSWDADAFSVEDPV	EIF3J	11	O75822
AAEDAAAQAVETPGW	HEBP2	11	Q9Y5Z4
DDETLTEEWTLDQPV	KIAA1109	1596	Q2LD37
GETSVSAEAAAPEWN	FER1L4	236	A9Z1Z3
SVQTDDEDSAEWEQP	BSN	2611	Q9UPA5
EKADTQDEWTPGTAV	MBD1	501	Q9UIS9
EPEDSSIVDNELWSE	PCM1	811	Q15154
DEALGEESGERWSPE	PER3	16	P56645
WPSVAFAEGSSSEEE	JRK	386	O75564
EEWVAVSDATEDPSG	FAM236A	26	A0A1B0GUQ0
TASSSQDGDPQIWDD	DDIAS	401	Q8IXT1
SLSVSSEEEEPDDGW	HMX2	46	A2RU54
IENWVTEGPSEDEAV	MEGF8	2336	Q7Z7M0
ESGVAGDPWKEETDT	KNOP1	296	Q1ED39
DTSERTGDHPEWDVQ	LRIT3	356	Q3SXY7
AEPEPSQEAESGSWE	MUC5AC	5631	P98088
REEEITSPGSNWEGT	PARM1	86	Q6UWI2
AWEQGSGVPDFDTAE	OAS2	576	P29728
ESSEVSQSEGEPWPD	GREB1L	1361	Q9C091
DTPEEDGITWTLDQS	IL12B	51	P29460
QDGSSSEAEDWETPK	MEIOSIN	606	C9JSJ3
APVSDWSSDEEDGSK	PLEKHH2	281	Q8IVE3
PDQVWETETIGESDF	ADCYAP1R1	86	P41586
EVENETGEATRPWGF	ACAN	431	P16112
AAVSDASLGPEWSQE	FAM182B	121	Q5T319
SEGLWSEDAPSDQSD	IFNAR2	486	P48551
SDLEDVGPTAEWNGD	KLC2	521	Q9H0B6
TGPLQDAEATEEGWA	OBSCN	2561	Q5VST9
AAVQPDDSDWTVTAD	OBSCN	4471	Q5VST9
DATGAEEEAPWAATE	MCAT	41	Q8IVS2
PAFAESVTEGDVRWE	DLST	76	P36957
SWASRGEAAPDQDEI	CTSA	21	P10619
QEDPPTWSEEEDGAS	PLEKHG6	661	Q3KR16
EEAGPSEAELDSTWR	APC2	1101	O95996
TGWVLEEEPAADSAF	ATP13A2	581	Q9NQ11
SDDSDLEDPVSAEAW	ESPL1	1396	Q14674
NEDPSDDEWEELSSS	HEATR3	376	Q7Z4Q2
WEAPVDSSTSGLEQD	CASC3	451	O15234
DEEEIGDSQAWEEPT	CCDC107	216	Q8WV48
AAWSSQVLLDPDGDE	C2CD2	591	Q9Y426
APVAGLTWEDSEGTE	CSF1	216	P09603
TNWVPEEASGEASEI	CSF1	301	P09603
DEIAVDRDVPWGVDS	FSCN1	161	Q16658
SQPDSDDEAEEIQWS	CDC123	56	O75794
LPELSDSGDEAAWED	PRMT3	21	O60678
WKQEPSEDEQEQGTS	CHD2	151	O14647
EEWVAVSDATEDPSG	FAM236B	26	A0A1B0GV22
ASGTDAAPEAWLEDE	C1orf226	91	A1L170
EWDVPASESGCEVSE	FNDC3B	691	Q53EP0
AVGTEWDIPRNESSD	FNIP1	926	Q8TF40
EDPSGEWVLEIENTS	FURIN	541	P09958
SWAETGHPDDELESE	GLYATL1B	151	A0A0U1RQE8
AGEWSEPVCEQTTHD	IL10RB	201	Q08334
EASQSAEISEEPAEW	MCF2	881	P10911
SGPWEEADAEAVARA	LTBP4	241	Q8N2S1
LGLDWSEESGEEPED	INO80D	321	Q53TQ3
GVEAAPETVEADAWV	KANK3	326	Q6NY19
DSWSDGEQEPITVDQ	KANSL2	146	Q9H9L4
ITVDQTWRGDPDSEA	KANSL2	156	Q9H9L4
TWRGDPDSEADSIDS	KANSL2	161	Q9H9L4
EGESAVAEDPTWGED	C2orf81	106	A6NN90
GKDEASSVEVTWPDG	CRTAC1	496	Q9NQ79
ITLSWAGPDTQEGDE	IGFN1	861	Q86VF2
DSSDEEGPQLWLAAA	DCST2	656	Q5T1A1
WPNDIFGSSSDDEVQ	FRY	2931	Q5TBA9
AGVPEDECWTGQTSD	FAM135B	511	Q49AJ0
SEWEGRISPEQVDTS	CEP295	1381	Q9C0D2
QSEAEASVDPSLSWG	UTP3	116	Q9NQZ2
EKESEDGPVSWDQTC	SLC39A12	296	Q504Y0
EQTEEGRPSAVEVWG	SLC39A14	141	Q15043
EVTWQQGFSSPEEGE	CFAP47	916	Q6ZTR5
VDVLDGEGWESQDAP	CLDN23	261	Q96B33
RWQLSSPDGVDTDDD	HELB	1016	Q8NG08
WSLPRAEGEAEEESD	CDC37L1	11	Q7L3B6
WEEVDSSPQPQGSES	INS-IGF2	146	F8WCM5
TEEEEIPSESSTEWD	KBTBD6	631	Q86V97
EANWDSDLETEGTDG	LRRC74B	36	Q6ZQY2
TLWTPDSTGGDQEDV	PARP10	576	Q53GL7
DGSELSEETSWPAFE	RALGPS2	401	Q86X27
VEAWDSSNDTVQPDS	JAG1	136	P78504
NLDDITWPSEIASED	POTEA	416	Q6S8J7
VPSTDWEDGDLTDTV	PLEKHM2	231	Q8IWE5
TGDWSSEEPEEEQEE	MEA1	46	Q16626
EEETEELTWSGSPRA	NAV1	916	Q8NEY1
ALASDSEEADEVPEW	KIF13B	1686	Q9NQT8
EDEEETTSQDWGTPR	RTN2	46	O75298
DATEAEEDFVDPWTV	WARS1	76	P23381
VAESWEEAADSGEID	SZRD1	6	Q7Z422
EEAPVSVWDEEEDGA	RGL2	51	O15211
GTEWDKDDLSPTAEV	STRN3	326	Q13033
VSEDVKWPNGISVDD	SORL1	916	Q92673
DEDDGPITVADAWRA	RNF19B	461	Q6ZMZ0
SNVDWEVETDNSDLP	PRUNE2	2481	Q8WUY3
ELPTEDEQGSWGIDD	SYNE2	6	Q8WXH0
SVSVETQGDDWDTDP	HCLS1	11	P14317
ENPAEAESWEEAASA	MAP3K21	681	Q5TCX8
EEEDVETGASQDWLP	MRM3	321	Q9HC36
SGIWEPGSQVFEEAE	NCAN	841	O14594
ESFWEEVASGEEPAL	NCAN	981	O14594
PLTGETAWEDEAENE	ARHGAP27	321	Q6ZUM4
LDEVGSWEEVSPATA	ARHGAP27	476	Q6ZUM4
WESNITEKDSDPADG	SETD5	1201	Q9C0A6
DWEIEQTPCEEVSES	SHQ1	126	Q6PI26
SQDPLWFSVAEEETE	PEX11A	161	O75192
ETPEHSSGEEDDWES	PPP1R15B	531	Q5SWA1
EGTEEGARWLTDEDT	OS9	601	Q13438
EPTWRSDSVDTEDSG	ABRA	181	Q8N0Z2
EEEPEWFSAGPTSQS	EIF4ENIF1	216	Q9NRA8
WEQTLPGSSDEEISD	AATF	86	Q9NY61
RPAGWAESVLEEDAS	ANGEL1	541	Q9UNK9
PVWGETDETSFEAGI	ASIC1	231	P78348
TAAASAVLDPEEEWE	NCAPD2	466	Q15021
DIDESSPGTEWERVA	CLTA	201	P09496
SSEVWRDEPAVATGA	CNGB1	176	Q14028
TPWGELEPSDEESSE	SF3B2	706	Q13435
EEVPHTQEISVSWEG	ZCWPW1	161	Q9H0M4
TQEISVSWEGEAAPE	ZCWPW1	166	Q9H0M4
CDIPEETWTGLESDV	ZCWPW1	296	Q9H0M4
WQSPDDSDEDLESDL	UNC13C	446	Q8NB66
DEPSAEQVSWEESQE	SSH2	1151	Q76I76
EEQVPQAWTAGTSSD	RIPK3	376	Q9Y572
GPEESAWGDEEDSLE	SHC2	321	P98077
DETENSLDVEWENPS	TNN	361	Q9UQP3
SDAWTGEDSAEPNSD	SOD3	16	P08294
GEDSAEPNSDSAEWI	SOD3	21	P08294
EQWLSTDVGNDAEEP	TOM1	421	O60784
TGANESWVVSDAPTE	RNF141	196	Q8WVD5
DPEEWQLSGDSTLNT	SP3	556	Q02447
DEWDDSSTVADEPGA	SNX18	156	Q96RF0
AQGPSGSSEWEDEQS	STC2	281	O76061
SAAAGEEDWVLPSEV	RNF25	6	Q96BH1
GLDNDAEGVWSPDIE	TEAD3	26	Q99594
PDGEASQTEDVDGTW	TNKS1BP1	1511	Q9C0C2
QSIWPSMDDDEEESG	TMEM115	301	Q12893
EASEFDEWEPEGTTL	NISCH	261	Q9Y2I1
IEHPTAGNTEAWEDT	NF1	766	P21359
VSSINSDLEWDPEDV	TMEM44	431	Q2T9K0
SDLEWDPEDVNLEGS	TMEM44	436	Q2T9K0
RQSDEEGPGEWSTLE	UNC13B	86	O14795
DTEDEEAWIQETEPS	SPTA1	801	P02549
CSDSQSWEDIAPEIE	TP53BP1	781	Q12888
LGSGEQEDESSPWFE	SUCO	596	Q9UBS9
SESDGEENIGWSTVN	SART1	596	O43290
DNDAEGVWSPDIEQS	TEAD4	36	Q15561
GADKDTEVAAPWTEE	SYMPK	771	Q92797
DPEWASEPILEGSDS	ZKSCAN2	26	Q63HK3
LQQGEDPWEVEKDSS	ZNF354B	66	Q96LW1
QEESTIPSWQEDEEE	TRANK1	1236	O15050
GAWETAASDIEPESR	VSIG10L2	646	P0DP72
DGGEEQTLSTEAETW	TAC4	21	Q86UU9
EAWSPEAQDPDGESS	ZNF785	86	A8K8V0
DPTQQDEASEGWVIG	UBASH3A	306	P57075
TETSSDWDPPAESQE	VWA5B1	781	Q5TIE3
VSADDEDWVRASGPS	ZAN	56	Q9Y493
AAEAGTPWAAQEDAD	NACAD	1006	O15069
SGGEEWVLDANDSPV	MYO9B	71	Q13459
EPWETISEEVNIAGD	NEDD4L	271	Q96PU5