Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionstructural constituent of presynaptic active zone

ERC2 ERC1

8.79e-058362GO:0098882
GeneOntologyMolecularFunctionATPase-coupled ion transmembrane transporter activity

ATP6V1E1 ATP6V1E2

8.51e-0424362GO:0042625
GeneOntologyMolecularFunctionATPase activity, coupled to transmembrane movement of ions, rotational mechanism

ATP6V1E1 ATP6V1E2

8.51e-0424362GO:0044769
GeneOntologyMolecularFunctionproton-transporting ATPase activity, rotational mechanism

ATP6V1E1 ATP6V1E2

8.51e-0424362GO:0046961
GeneOntologyMolecularFunctionstructural constituent of synapse

ERC2 ERC1

2.60e-0342362GO:0098918
GeneOntologyBiologicalProcessmaintenance of presynaptic active zone structure

ERC2 ERC1

4.18e-056352GO:0048790
GeneOntologyBiologicalProcessregulation of calcium-dependent activation of synaptic vesicle fusion

ERC2 ERC1

5.84e-057352GO:0150037
GeneOntologyBiologicalProcesspresynaptic active zone organization

ERC2 ERC1

1.25e-0410352GO:1990709
GeneOntologyBiologicalProcesspositive regulation of synaptic vesicle fusion to presynaptic active zone membrane

ERC2 ERC1

2.16e-0413352GO:0031632
GeneOntologyBiologicalProcesspositive regulation of synaptic vesicle membrane organization

ERC2 ERC1

2.16e-0413352GO:1901634
GeneOntologyBiologicalProcesscalcium-dependent activation of synaptic vesicle fusion

ERC2 ERC1

2.16e-0413352GO:0099502
GeneOntologyBiologicalProcessneuron cellular homeostasis

ERC2 ATP6V1E1 ERC1

3.88e-0484353GO:0070050
GeneOntologyBiologicalProcessregulation of synaptic vesicle fusion to presynaptic active zone membrane

ERC2 ERC1

5.21e-0420352GO:0031630
GeneOntologyBiologicalProcesspositive regulation of vesicle fusion

ERC2 ERC1

5.21e-0420352GO:0031340
GeneOntologyBiologicalProcessregulation of synaptic vesicle membrane organization

ERC2 ERC1

5.21e-0420352GO:1901632
GeneOntologyCellularComponentcytoskeleton of presynaptic active zone

ERC2 ERC1

7.15e-058342GO:0048788
GeneOntologyCellularComponentpresynaptic cytoskeleton

ERC2 ERC1

2.31e-0414342GO:0099569
GeneOntologyCellularComponentproton-transporting two-sector ATPase complex, catalytic domain

ATP6V1E1 ATP6V1E2

4.32e-0419342GO:0033178
GeneOntologyCellularComponentpresynaptic active zone cytoplasmic component

ERC2 ERC1

6.36e-0423342GO:0098831
GeneOntologyCellularComponentouter kinetochore

ZWINT SPDL1

6.93e-0424342GO:0000940
GeneOntologyCellularComponentpresynaptic active zone

ERC2 ERC1 ARHGAP44

1.54e-03141343GO:0048786
GeneOntologyCellularComponentcell cortex region

ERC2 ERC1

2.43e-0345342GO:0099738
GeneOntologyCellularComponentcytoplasmic region

ERC2 SPAG17 ERC1 CEP162

2.67e-03360344GO:0099568
GeneOntologyCellularComponentcell cortex

EXOC6B ERC2 MACF1 ERC1

2.97e-03371344GO:0005938
GeneOntologyCellularComponentproton-transporting two-sector ATPase complex

ATP6V1E1 ATP6V1E2

3.36e-0353342GO:0016469
DomainATPase_V1/A1-cplx_esu

ATP6V1E1 ATP6V1E2

3.22e-062342IPR002842
DomainCast

ERC2 ERC1

3.22e-062342PF10174
DomainELKS/CAST

ERC2 ERC1

3.22e-062342IPR019323
DomainvATP-synt_E

ATP6V1E1 ATP6V1E2

3.22e-062342PF01991
DomainBAR

ARHGAP17 ARHGAP44

3.33e-0415342PF03114
DomainBAR

ARHGAP17 ARHGAP44

3.33e-0415342SM00721
DomainBAR_dom

ARHGAP17 ARHGAP44

3.80e-0416342IPR004148
DomainBAR

ARHGAP17 ARHGAP44

5.39e-0419342PS51021
Domain-

ARHGAP17 ARHGAP44

1.36e-03303421.20.1270.60
DomainAH/BAR-dom

ARHGAP17 ARHGAP44

1.36e-0330342IPR027267
DomainRhoGAP

ARHGAP17 ARHGAP44

5.68e-0362342SM00324
DomainRhoGAP

ARHGAP17 ARHGAP44

5.86e-0363342PF00620
DomainRHOGAP

ARHGAP17 ARHGAP44

6.04e-0364342PS50238
DomainRhoGAP_dom

ARHGAP17 ARHGAP44

6.04e-0364342IPR000198
Domain-

ARHGAP17 ARHGAP44

6.04e-03643421.10.555.10
DomainCH

EHBP1 MACF1

6.23e-0365342SM00033
DomainCH

EHBP1 MACF1

7.19e-0370342PF00307
Domain-

EHBP1 MACF1

7.39e-03713421.10.418.10
DomainCH

EHBP1 MACF1

7.80e-0373342PS50021
DomainCH-domain

EHBP1 MACF1

8.21e-0375342IPR001715
DomainRho_GTPase_activation_prot

ARHGAP17 ARHGAP44

1.12e-0288342IPR008936
PathwayREACTOME_ROS_AND_RNS_PRODUCTION_IN_PHAGOCYTES

ATP6V1E1 ATP6V1E2 LPO

3.82e-0536263M26923
PathwayREACTOME_ROS_AND_RNS_PRODUCTION_IN_PHAGOCYTES

ATP6V1E1 ATP6V1E2 LPO

4.50e-0538263MM14519
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

POLRMT EHBP1 PSMD1 UBR5 KDM5A ERC1 SPDL1

2.13e-0741836734709266
Pubmed

Defective assembly of a hybrid vacuolar H(+)-ATPase containing the mouse testis-specific E1 isoform and yeast subunits.

ATP6V1E1 ATP6V1E2

1.04e-06236218662668
Pubmed

ELKS controls the pool of readily releasable vesicles at excitatory synapses through its N-terminal coiled-coil domains.

ERC2 ERC1

1.04e-06236227253063
Pubmed

Early ependymal tumor with MN1-BEND2 fusion: a mostly cerebral tumor of female children with a good prognosis that is distinct from classical astroblastoma.

BEND2 MN1

1.04e-06236236604386
Pubmed

The Bruchpilot cytomatrix determines the size of the readily releasable pool of synaptic vesicles.

ERC2 ERC1

1.04e-06236223960145
Pubmed

Double deletion of the active zone proteins CAST/ELKS in the mouse forebrain causes high mortality of newborn pups.

ERC2 ERC1

1.04e-06236231996256
Pubmed

A human gene, ATP6E1, encoding a testis-specific isoform of H(+)-ATPase subunit E.

ATP6V1E1 ATP6V1E2

1.04e-06236212036578
Pubmed

CAST2: identification and characterization of a protein structurally related to the presynaptic cytomatrix protein CAST.

ERC2 ERC1

1.04e-06236214723704
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

ERC2 MACF1 PSMD1 SPAG17 KDM5A TTC16 FAM50A ERC1 ENY2 CCDC158

1.38e-061442361035575683
Pubmed

The active zone protein family ELKS supports Ca2+ influx at nerve terminals of inhibitory hippocampal neurons.

ERC2 ERC1

3.12e-06336225209271
Pubmed

Spinal cord astroblastoma with an EWSR1-BEND2 fusion classified as a high-grade neuroepithelial tumour with MN1 alteration.

BEND2 MN1

3.12e-06336231863478
Pubmed

A proton pump ATPase with testis-specific E1-subunit isoform required for acrosome acidification.

ATP6V1E1 ATP6V1E2

3.12e-06336211872743
Pubmed

A genome-wide association study identifies two risk loci for congenital heart malformations in Han Chinese populations.

SPAG17 MAML3

3.12e-06336223708190
Pubmed

Cytomatrix proteins CAST and ELKS regulate retinal photoreceptor development and maintenance.

ERC2 ERC1

3.12e-06336230190286
Pubmed

A family of RIM-binding proteins regulated by alternative splicing: Implications for the genesis of synaptic active zones.

ERC2 ERC1

6.24e-06436212391317
Pubmed

CAST/ELKS Proteins Control Voltage-Gated Ca2+ Channel Density and Synaptic Release Probability at a Mammalian Central Synapse.

ERC2 ERC1

6.24e-06436229996090
Pubmed

Fusion Competent Synaptic Vesicles Persist upon Active Zone Disruption and Loss of Vesicle Docking.

ERC2 ERC1

6.24e-06436227537483
Pubmed

SAD-B Phosphorylation of CAST Controls Active Zone Vesicle Recycling for Synaptic Depression.

ERC2 ERC1

6.24e-06436227626661
Pubmed

The B1 subunit of the H+ATPase is a PDZ domain-binding protein. Colocalization with NHE-RF in renal B-intercalated cells.

ATP6V1E1 ATP6V1E2

1.04e-05536210748165
Pubmed

ELKS1 Captures Rab6-Marked Vesicular Cargo in Presynaptic Nerve Terminals.

ERC2 ERC1

1.04e-05536232521280
Pubmed

Rebuilding essential active zone functions within a synapse.

ERC2 ERC1

2.18e-05736235176221
Pubmed

Munc13 supports fusogenicity of non-docked vesicles at synapses with disrupted active zones.

ERC2 ERC1

2.18e-05736236398873
Pubmed

Dopamine Secretion Is Mediated by Sparse Active Zone-like Release Sites.

ERC2 ERC1

2.18e-05736229398114
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

ARHGAP17 ERC2 MACF1 UBR5 ERC1 ZWINT

2.88e-0558836638580884
Pubmed

A yeast four-hybrid system identifies Cdk-activating kinase as a regulator of the XPD helicase, a subunit of transcription factor IIH.

HOXC10 KDM5A

2.91e-05836211445587
Pubmed

Interaction of the ERC family of RIM-binding proteins with the liprin-alpha family of multidomain proteins.

ERC2 ERC1

3.73e-05936212923177
Pubmed

External push and internal pull forces recruit curvature-sensing N-BAR domain proteins to the plasma membrane.

ARHGAP17 ARHGAP44

4.66e-051036222750946
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

ERC2 MACF1 UBR5 KDM5A ERC1 CYTH1 ARHGAP44

5.05e-0596336728671696
Pubmed

Post-developmental plasticity of the primary rod pathway allows restoration of visually guided behaviors.

ERC2 ERC1

8.07e-051336236179691
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

ERC2 MACF1 UBR5 ERC1

8.54e-0522536412168954
Pubmed

Calcium channels link the muscle-derived synapse organizer laminin β2 to Bassoon and CAST/Erc2 to organize presynaptic active zones.

ERC2 ERC1

9.41e-051436221228161
Pubmed

Analysis of the cat eye syndrome critical region in humans and the region of conserved synteny in mice: a search for candidate genes at or near the human chromosome 22 pericentromere.

ATP6V1E1 KDM5A

1.08e-041536211381032
Pubmed

Rich, a rho GTPase-activating protein domain-containing protein involved in signaling by Cdc42 and Rac1.

ARHGAP17 ARHGAP44

1.24e-041636211431473
Pubmed

A human MAP kinase interactome.

EHBP1 ARHGAP17 MACF1 PSMD1 CSN1S1

1.38e-0448636520936779
Pubmed

mSYD1A, a mammalian synapse-defective-1 protein, regulates synaptogenic signaling and vesicle docking.

ERC2 ERC1

1.96e-042036223791195
Pubmed

Lipofuscin is formed independently of macroautophagy and lysosomal activity in stress-induced prematurely senescent human fibroblasts.

ATP6V1E1 ATP6V1E2

1.96e-042036222982048
Pubmed

Intersectin (ITSN) family of scaffolds function as molecular hubs in protein interaction networks.

ERC1 CYTH1 SPDL1

2.09e-0411136322558309
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

EHBP1 ARHGAP17 MACF1 KDM5A ERC1 CEP162

2.34e-0486136636931259
Pubmed

Proton translocation driven by ATP hydrolysis in V-ATPases.

ATP6V1E1 ATP6V1E2

2.38e-042236212788495
Pubmed

The vacuolar (H+)-ATPases--nature's most versatile proton pumps.

ATP6V1E1 ATP6V1E2

2.38e-042236211836511
Pubmed

Revised nomenclature for mammalian vacuolar-type H+ -ATPase subunit genes.

ATP6V1E1 ATP6V1E2

2.38e-042236214580332
Pubmed

Neurotransmitter release: the dark side of the vacuolar-H+ATPase.

ATP6V1E1 ATP6V1E2

2.38e-042236214597263
Pubmed

Coupling of rotation and catalysis in F(1)-ATPase revealed by single-molecule imaging and manipulation.

ATP6V1E1 ATP6V1E2

2.38e-042236217662945
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

ERC2 MACF1 PSMD1 KDM5A ERC1 CYTH1 NR1D2

3.01e-04128536735914814
Pubmed

Receptor-mediated endocytosis: the intracellular journey of transferrin and its receptor.

ATP6V1E1 ATP6V1E2

3.08e-04253622874839
Pubmed

Overlapping Activities of Two Neuronal Splicing Factors Switch the GABA Effect from Excitatory to Inhibitory by Regulating REST.

ERC2 MACF1 ERC1

3.18e-0412836330995482
Pubmed

Redundant functions of RIM1alpha and RIM2alpha in Ca(2+)-triggered neurotransmitter release.

ERC2 ERC1

3.33e-042636217124501
Pubmed

Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.

IQCN ERC1 ENY2 CEP162 CYTH1 ZWINT

3.43e-0492536628986522
Pubmed

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.

ATP6V1E1 FAM50A ERC1 ENY2 CEP162

5.06e-0464536525281560
Pubmed

Targeting the Otub1/c-Maf axis for the treatment of multiple myeloma.

PSMD1 UBR5

5.72e-043436232842143
Pubmed

Global phosphoproteome analysis on human HepG2 hepatocytes using reversed-phase diagonal LC.

MACF1 PSMD1

6.42e-043636216097034
Pubmed

A neurogenomics approach to gene expression analysis in the developing brain.

KERA MACF1 KDM5A

7.28e-0417036315582152
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

EXOC6B EHBP1 MACF1 PSMD1 IQCN MAML3 ARHGAP44

7.28e-04148936728611215
Pubmed

Human variation in alcohol response is influenced by variation in neuronal signaling genes.

ERC2 ERC1 BDKRB2

7.40e-0417136320201926
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

ERC2 MACF1 UBR5 ERC1

8.10e-0440736412693553
Pubmed

Aggresomal sequestration and STUB1-mediated ubiquitylation during mammalian proteaphagy of inhibited proteasomes.

PSMD1 UBR5

8.33e-044136232723828
Pubmed

MITOL regulates phosphatidic acid-binding activity of RMDN3/PTPIP51.

PSMD1 UBR5

8.33e-044136234964862
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

POLRMT MACF1 UBR5 KDM5A ERC1 ENY2

9.20e-04111636631753913
Pubmed

Proteomic Analysis of the EWS-Fli-1 Interactome Reveals the Role of the Lysosome in EWS-Fli-1 Turnover.

ARHGAP17 FAM50A ERC1 SPDL1

9.50e-0442536424999758
Cytoband4q21.1

CSN1S1 CCDC158

3.91e-04373624q21.1
GeneFamilyN-BAR domain containing

ARHGAP17 ARHGAP44

6.14e-05121821289
GeneFamilyV-type ATPases

ATP6V1E1 ATP6V1E2

2.34e-0423182415
GeneFamilyRho GTPase activating proteins|BCH domain containing

ARHGAP17 ARHGAP44

1.11e-0350182721
ToppCelldroplet-Limb_Muscle-MUSCLE|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KERA FILIP1 MACF1 ERC1 NR1D2

4.79e-07194365e3d63874111d1e8da3977329426e4dcf68d6de87
ToppCellCiliated_cells-A-Donor_01|World / lung cells shred on cell class, cell subclass, sample id

CCDC178 ERICH3 SPAG17 TTC16

8.93e-0616336443194c6127df1ce3d29242f719645de3c11fd7c0
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-SMC_prolif-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

FILIP1 ARHGAP44 ZWINT SPDL1

1.77e-0519436478dcb9d48259afabe73b41c5508a73a8d62339a4
ToppCellParenchymal-NucSeq|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations

EXOC6B ERC1 MAML3 ARHGAP44

1.92e-051983641996373bdccc55aac347d349bd22f6aad6d0c668
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

EXOC6B UBR5 ERC1 MAML3

1.96e-0519936494b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCellStriatum-Neuronal|Striatum / BrainAtlas - Mouse McCarroll V32

ERC2 ATP6V1E1 ARHGAP44 ZWINT

2.00e-05200364c888fd487990cad482a4ca47601cdebc0ca3f3ce
ToppCellmetastatic_Brain-Myeloid_cells-Pleural_Mac|Myeloid_cells / Location, Cell class and cell subclass

DUS3L CSN1S1 BDKRB2

2.12e-041443636f1158c85e1d50ef6f2c67abdb2dc855a9786b9a
ToppCelllung-Ciliated_Epithelia|lung / shred on tissue and cell subclass

ERICH3 SPAG17 TTC16

3.28e-0416736326cf1cfa58ee74794449a87eb19cd896e1ec8892
ToppCellE16.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ERICH3 SPAG17 TTC16

3.34e-04168363fa7c0303918cea04e3f4c4f3cb079be19004d214
ToppCellE16.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ERICH3 SPAG17 TTC16

3.34e-041683637edcab103c69e928d5c19a0d218ffb3ae32f9e70
ToppCell15-Distal-Epithelial-Multiciliated_cell|Distal / Age, Tissue, Lineage and Cell class

ERICH3 SPAG17 TTC16

3.39e-04169363425d89ab69e9f9eb3df84056676423e390cc6ab1
ToppCellwk_08-11-Epithelial-Proximal_epithelial-Deuterosomal|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

ERICH3 SPAG17 TTC16

3.57e-0417236308ad76412c9cc3504141797b44b88478ced87476
ToppCellPND07-28-samps-Epithelial-Epithelial-non_alveolar-Ciliated_cell_of_lung_parenchyma|PND07-28-samps / Age Group, Lineage, Cell class and subclass

ERICH3 SPAG17 TTC16

3.70e-04174363f41d05a3703d7092bd3c4a97c15ae13069aaa4ad
ToppCellPND07-28-samps-Epithelial-Epithelial-non_alveolar|PND07-28-samps / Age Group, Lineage, Cell class and subclass

ERICH3 SPAG17 TTC16

3.76e-04175363c01a15b2084da4a18f8ff3623f44eb9dfe499f10
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPAG17 TTC16 CCDC158

3.88e-04177363e8bb4f8ecd5e283efec966b9fc2040a6152d5551
ToppCellCiliated_cells-B-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

ERICH3 SPAG17 TTC16

3.88e-04177363c38138fb5ad9766c2d240811210c854338cd612e
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal-Ependyma|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPAG17 TTC16 CCDC158

3.95e-04178363579cdc14f28b459e200ae2102e0bd4df8a2c0dcb
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal-ependymal_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPAG17 TTC16 CCDC158

3.95e-04178363b1db59344c074c7c80169fc2c5cd5fc89f3fe463
ToppCell343B-Lymphocytic-NK_cells-NK_cell_A2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

ARHGAP17 DUS3L CEP162

4.08e-0418036362511d76d24b836839c3dcc2bf30485ffe9401e2
ToppCellwk_08-11-Epithelial-Proximal_epithelial-Ciliated|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

ERICH3 SPAG17 TTC16

4.15e-041813638eed9d46d924b16f6dd1a025ff612244b02b4391
ToppCellAdult-Epithelial-ciliated_cell-D122|Adult / Lineage, Cell type, age group and donor

ERICH3 SPAG17 TTC16

4.21e-041823637ded554a4b441e6496db673ba206c0d76ccad7d9
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SPAG17 ERC1 ARHGAP44

4.28e-04183363b5ede5a0048c585b73c00e88aeddbcaf669347b1
ToppCell10x5'-lymph-node_spleen-Myeloid_Dendritic-Cycling_Dendritic|lymph-node_spleen / Manually curated celltypes from each tissue

ERC2 MN1 ZWINT

4.42e-04185363912d8efdc37820dbb07736221a98af929e5a7c97
ToppCellNS-moderate-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

FILIP1 ERICH3 SPAG17

4.42e-041853635e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCellNS-critical-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

FILIP1 ERICH3 SPAG17

4.49e-0418636376033438426d8f9c72cd6691a7baf92104c9f03d
ToppCellNS-moderate-d_07-13-Epithelial-Ciliated|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

FILIP1 ERICH3 SPAG17

4.49e-0418636385787ff207f109ec7e3c0f729ba9bda739c2fdc9
ToppCellfacs-Lung-EPCAM-3m-Epithelial-Ciliated_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERICH3 SPAG17 TTC16

4.56e-0418736304dba2ed09ee4180830bdf0191921696697ea234
ToppCellfacs-Lung-EPCAM-3m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERICH3 SPAG17 TTC16

4.56e-04187363805dafe22f835ece4dd091d8030d0a63b52a48dd
ToppCellCiliated_cells-B-HP_01|World / lung cells shred on cell class, cell subclass, sample id

ERICH3 SPAG17 TTC16

4.56e-04187363bc1f33f332ac939c2425f510173430ca2ba0c3ee
ToppCellControl-Endothelial-VE_Peribronchial|Endothelial / Disease state, Lineage and Cell class

CCDC178 BDKRB2 CYTH1

4.56e-041873635429ae85942b8ec3895cceb63c663de3c24ca064
ToppCellLA-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

EXOC6B FILIP1 ERC2

4.63e-041883636d249fe92d51a19da19ec14bb2262d394255d577
ToppCell-Unknown-Endothelial-Myofibroblast| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FILIP1 UBR5 ERC1

4.63e-041883636468fa95ad0395395301115286f2d8c0df5d3882
ToppCell-Unknown-Endothelial| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FILIP1 UBR5 ERC1

4.63e-041883637a81ac5c79c3eb26639b52d2b9fd5e7ef9798fd6
ToppCell-Unknown| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FILIP1 UBR5 ERC1

4.63e-041883639cb718bfe1358c6fd842f096e228eb0abb9aefc6
ToppCellMulticiliated|World / shred by cell class for nasal brushing

FILIP1 ERICH3 SPAG17

4.70e-0418936334b110aef839376228c5a403a6b5047a945f472b
ToppCelltumor_Lymph_Node_/_Brain-Fibroblasts-Pericytes|Fibroblasts / Location, Cell class and cell subclass

FILIP1 BEND2 ARHGAP44

4.70e-04189363f4865b7db16de15120504147a8016ac522ad242a
ToppCellNasal_Brush-Epithelial-Ciliated_2|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

FILIP1 ERICH3 SPAG17

4.78e-041903639ce7df056bfb24d70db4c3c4a2c57d89115de877
ToppCellNasal_Brush-Epithelial-Ciliated_2|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

FILIP1 ERICH3 SPAG17

4.78e-04190363833481ace2800354712e2ce709d5cdfd0aed3d42
ToppCellfacs-Lung-3m-Epithelial-airway_epithelial-lung_ciliated_cell-ciliated_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ERICH3 SPAG17 TTC16

4.85e-04191363649fcb62ad15de2f83e61591e43923a717664ae7
ToppCellfacs-Lung-3m-Epithelial-airway_epithelial-lung_ciliated_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ERICH3 SPAG17 TTC16

4.85e-041913639621e22e14ea069f22713947c9faa2d882abe5fe
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FILIP1 ARHGAP17 ARHGAP44

4.85e-041913637b0d42a877540dbb346a76a62403e0d5d3e07fa6
ToppCellLA-03._Atrial_Cardiomyocyte|LA / Chamber and Cluster_Paper

EXOC6B FILIP1 ERC2

4.85e-041913635d1b674eb7703830b7ce8bbeac3363cabd0e6ae9
ToppCellwk_15-18-Epithelial-Proximal_epithelial-MUC16+_ciliated|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

ERICH3 SPAG17 TTC16

4.85e-04191363e81cd65dbf0ef1c2ab7088f73ce605d456dd3a7a
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FILIP1 ARHGAP17 ARHGAP44

4.85e-04191363cd854b9c426924fdc84bf7f411f6dea447143e79
ToppCell10x5'v1-week_12-13-Mesenchymal_fibro-stroma|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

KERA HOXC10 BDKRB2

4.92e-041923634ed5040594ba2d0639f0990697504ecef872ca70
ToppCellhuman_hepatoblastoma-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

EHBP1 UBR5 KDM5A

4.92e-04192363916fbec1c7ab7969bda711886ac88e877e30c280
ToppCell10x5'v1-week_12-13-Mesenchymal_fibro|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

KERA HOXC10 BDKRB2

4.92e-04192363d4f5d6653564c2c5d0f5f7c932d89cb1b1412844
ToppCellmulticiliated|World / shred by cell class for turbinate

FILIP1 ERICH3 SPAG17

4.92e-041923630f89ea0deb651ca11531c51ee94e0233608d22ea
ToppCellrenal_cortex_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

EXOC6B MACF1 ERC1

4.92e-04192363e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCellnucseq|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ERC1 MAML3 CYTH1

5.00e-04193363779276e775cb2492e8dd36436295a536084a6415
ToppCellhuman_hepatoblastoma|World / Sample and Cell Type and Tumor Cluster (all cells)

EHBP1 UBR5 KDM5A

5.00e-04193363e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCellNS-moderate-d_0-4|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

FILIP1 ERICH3 SPAG17

5.00e-04193363ea345d34440b25f65358a53dc72831998d1c3620
ToppCellNS-critical-d_07-13-Epithelial-Ciliated|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

FILIP1 ERICH3 SPAG17

5.08e-041943631ae8a10e508e672e6677f0e3c986ac30d05adeb3
ToppCellNS-critical-LOC-Epithelial-Ciliated|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

FILIP1 ERICH3 SPAG17

5.15e-0419536334e37cff4849696ca4ba5dd8fd2cf98fed8bc912
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FILIP1 ERC2 MACF1

5.15e-041953633e519cffa6144a62b06124642a14c9ff39b76554
ToppCellmoderate-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

FILIP1 ERICH3 SPAG17

5.15e-041953633486eae5fdb062a75a907b896c9d7b396d2aa195
ToppCellmoderate-Epithelial-Ciliated|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

FILIP1 ERICH3 SPAG17

5.15e-04195363e80f5cdf0b18066b3e6c2f5452e58f101c67932c
ToppCellBL-critical-LOC-Epithelial-Ciliated|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

FILIP1 ERICH3 SPAG17

5.15e-0419536307a6bcef6af93ed87df455dee624037cb75e011a
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FILIP1 ERC2 MACF1

5.15e-041953637796ea9247f4c63762f0de8490fed08b9717fa23
ToppCellT_cells-GZMK+_T_cells|T_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

CSN1S1 KDM5A TTC16

5.15e-04195363003ea7ddec6c1c98d2f6470bb51ebd97450eb936
ToppCellBronchial-NucSeq|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations

EXOC6B ERC1 MAML3

5.23e-04196363ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCellCOPD-Multiplet|COPD / Disease state, Lineage and Cell class

MACF1 ERICH3 SPAG17

5.23e-041963636d02d494196e3f857d53eea46d9419690d43beca
ToppCellcritical-Epithelial-Ciliated|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

FILIP1 ERICH3 SPAG17

5.23e-0419636327b855c6e1ae44f16db998cf0e81bd686b9cee7e
ToppCellNS-control-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

FILIP1 ERICH3 SPAG17

5.23e-04196363d46ab80554dd3c1cc81e1938ea2acfd5e85c6d2a
ToppCellCOPD-Multiplet-Multiplet|COPD / Disease state, Lineage and Cell class

MACF1 ERICH3 SPAG17

5.23e-04196363af4cdc61830685a888a1209826c23bcf54a43084
ToppCellPSB-critical-LOC-Epithelial-Ciliated|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

FILIP1 ERICH3 SPAG17

5.31e-041973636865f4831eb23794fb88a8649d48d497bbae3f44
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_ciliated-Deuterosomal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ERICH3 SPAG17 CCDC158

5.31e-041973636e4a411ef823ce9e16f420e185e21fa19d13af34
ToppCellNS-moderate-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

FILIP1 ERICH3 SPAG17

5.31e-0419736371fea4aa6ce96c7693fa94792d08770622873850
ToppCellcontrol-Epithelial-Ciliated|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

FILIP1 ERICH3 SPAG17

5.31e-04197363d4e963c1f82996371bf3d63578ee9fce8e00c5a8
ToppCellcontrol-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

FILIP1 ERICH3 SPAG17

5.31e-04197363e453d085182364ca347cbcc9dc995c62c3353016
ToppCellLPS_only-Epithelial_airway-airway_epithelial-Ciliated|LPS_only / Treatment groups by lineage, cell group, cell type

ERICH3 SPAG17 TTC16

5.39e-041983636d90b541fde357fbb40f8f7d4e8628a48b679718
ToppCellcritical-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

FILIP1 ERICH3 SPAG17

5.39e-04198363ee2c8385c0bf4ea9f5c9517b52cf131af3fbdd40
ToppCell18-Airway-Mesenchymal-Mesenchyme_RSPO2+|Airway / Age, Tissue, Lineage and Cell class

MACF1 ZWINT SPDL1

5.46e-041993637ac35e8f45dcdc702422dabd8f3e4d03e2bf61af
ToppCellLPS_anti-TNF-Epithelial_airway-airway_epithelial-Ciliated|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ERICH3 SPAG17 TTC16

5.46e-0419936315f7814b7074170eee7ccacaa670b1d128fc68bb
ToppCellLPS_IL1RA_TNF-Epithelial_airway-airway_epithelial-Ciliated|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

ERICH3 SPAG17 TTC16

5.55e-0420036396701a4d57753f5ec0dd5c7550054bbcc946bc5f
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-Ciliated|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

ERICH3 SPAG17 TTC16

5.55e-04200363ddd39b754bfaa98249d497dfb7e97ec58617a11a
ToppCellParenchyma_Control_(B.)-Epithelial-TX-Ciliated|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

ERICH3 SPAG17 TTC16

5.55e-04200363a521cf837cadf280505ff9d7e641a205af7d6513
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-Ciliated-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ERICH3 SPAG17 TTC16

5.55e-04200363918b576fd9491d23c2bb9d663fa5fb3505cb1c7e
ToppCellTracheal-10x3prime_v2-Stromal-Peri/Epineurial_-NAF_epineurial|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

EXOC6B DUS3L BDKRB2

5.55e-0420036324e13b6d9d2d8b29df1f02544ea9c50084d9e75c
ToppCellLPS_IL1RA-Epithelial_airway-airway_epithelial-Ciliated|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ERICH3 SPAG17 TTC16

5.55e-042003634992dbf0514d674017315dbd20d91dfec0c608e9
Diseaseblood strontium measurement

CEP162 ZWINT

4.44e-0427342EFO_0021531
Diseasemultiple system atrophy

ENY2 ARHGAP44

9.78e-0440342EFO_1001050
Diseaseresponse to angiotensin-converting enzyme inhibitor, Cough

EXOC6B ZWINT

1.29e-0346342EFO_0005325, HP_0012735
Diseaserenal agenesis, unilateral

ERC2 KDM5A

2.26e-0361342MONDO_0019636
Diseasecortical surface area measurement

EXOC6B FILIP1 ERC2 MACF1 SPAG17 CEP162

3.98e-031345346EFO_0010736
Diseasethalamus volume

ERC2 MACF1

4.33e-0385342EFO_0006935
Diseasebeta-amyloid 1-42 measurement

FILIP1 BDKRB2

4.53e-0387342EFO_0004670
Diseaseosteoarthritis, hip

FILIP1 SPAG17

5.06e-0392342EFO_1000786
Diseasebody surface area

KERA FILIP1 MACF1 CYTH1

6.17e-03643344EFO_0022196
Diseasemalaria

EXOC6B MAML3

6.18e-03102342EFO_0001068

Protein segments in the cluster

PeptideGeneStartEntry
VMKFRNSIGNSQRMN

ERICH3

206

Q5RHP9
MNKDAQMRAAINQKL

ENY2

6

Q9NPA8
QIMQVLRNNEMQKFK

BDKRB2

246

P30411
MNRSTKFQQIVRGMN

DUS3L

411

Q96G46
QLKQQTQNRMKLMAD

ERC1

971

Q8IUD2
GFKIRQQMRQQQMAA

IQCN

1126

Q9H0B3
MAAQQQQRAKLMQQK

MAML3

471

Q96JK9
QPMNNSKMREKRNLQ

BEND2

621

Q8NDZ0
MNGMNRQRNILREKQ

CSN1S1

46

P47710
EALKQQRSRKNMINM

CCDC178

186

Q5BJE1
QNKMMTGELRNKLFQ

LPO

526

P22079
ERKNMQRNKQVAMGR

CYTH1

56

Q15438
QRNKQVAMGRKKFNM

CYTH1

61

Q15438
MKDTSRKNNMFAQFR

EXOC6B

771

Q9Y2D4
LKQQTQNRMKLMADN

ERC2

901

O15083
NMQMRQRKGTLSVNF

KDM5A

276

P29375
NMLNAQKQQVQFMLK

MACF1

4611

Q9UPN3
KMRKGNTMQQFLQKA

FAM50A

216

Q14320
LQKDRRMMLSNQNSK

CEP162

1111

Q5TB80
MLVNKKNALIRRMNQ

EHBP1

1121

Q8NDI1
FQNRRMKLKKMNREN

HOXC10

316

Q9NYD6
KNQAMSSMIRNQEKR

CCDC158

1086

Q5M9N0
RTQQMRMQRLKAKLQ

POLRMT

131

O00411
LMIKQMASRNQQQRL

MN1

556

Q10571
LKNENCSIMRMNRNR

NR1D2

141

Q14995
LQQRFMEEENKNKNM

FILIP1

751

Q7Z7B0
MKKQFNRMKQLANQT

ARHGAP17

1

Q68EM7
LKNLMQLNMAKNALR

KERA

191

O60938
LKLCMSLMQNKQFRN

PSMD1

181

Q99460
NVFNREQMQRMKLQI

SPDL1

286

Q96EA4
MKKQFNRMRQLANQT

ARHGAP44

1

Q17R89
RFAKQIRQQYVMKMN

SPAG17

641

Q6Q759
KKQMAMEKRRAVQNQ

ZWINT

141

O95229
RMLLQKMVAQAQQAR

TTC16

241

Q8NEE8
QQKKIQMSNLMNQAR

ATP6V1E1

66

P36543
ANLKNVMNMQNRQKK

UBR5

2106

O95071
QQKKILMSTMRNQAR

ATP6V1E2

66

Q96A05