Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainBROMODOMAIN_1

BRWD3 TRIM33 BPTF BRD8

1.24e-04371304PS00633
DomainBromodomain

BRWD3 TRIM33 BPTF BRD8

1.38e-04381304PF00439
DomainBROMODOMAIN_2

BRWD3 TRIM33 BPTF BRD8

1.86e-04411304PS50014
DomainPRY

TRIM39 BTN2A1 BTNL3 TRIM16L

2.04e-04421304PF13765
DomainBromodomain

BRWD3 TRIM33 BPTF BRD8

2.04e-04421304IPR001487
DomainBROMO

BRWD3 TRIM33 BPTF BRD8

2.04e-04421304SM00297
Domain-

BRWD3 TRIM33 BPTF BRD8

2.04e-044213041.20.920.10
DomainPRY

TRIM39 BTN2A1 BTNL3 TRIM16L

3.44e-04481304SM00589
DomainPRY

TRIM39 BTN2A1 BTNL3 TRIM16L

3.44e-04481304IPR006574
DomainSPRY

TRIM39 BTN2A1 SPRYD7 BTNL3 TRIM16L

3.54e-04871305SM00449
DomainSPRY

TRIM39 BTN2A1 SPRYD7 BTNL3 TRIM16L

5.06e-04941305PF00622
DomainSPRY_dom

TRIM39 BTN2A1 SPRYD7 BTNL3 TRIM16L

5.06e-04941305IPR003877
DomainB30.2/SPRY

TRIM39 BTN2A1 SPRYD7 BTNL3 TRIM16L

5.31e-04951305IPR001870
DomainB302_SPRY

TRIM39 BTN2A1 SPRYD7 BTNL3 TRIM16L

5.31e-04951305PS50188
DomainDUF3398

DOCK9 DOCK10

7.08e-0461302PF11878
DomainDOCK_C/D_N

DOCK9 DOCK10

7.08e-0461302IPR021816
DomainHEAT

TOGARAM1 GCN1 TBCD IPO11

7.11e-04581304IPR000357
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

CASP8AP2 TTC28 SYNE1 DOCK9 DOCK10 TOGARAM1 ADGRA2 MYOF TLN2 GCN1

1.77e-082251331012168954
Pubmed

DSSylation, a novel protein modification targets proteins induced by oxidative stress, and facilitates their degradation in cells.

EEF1A2 TXNRD1 TRIM33 FEN1 TLN2

2.24e-0735133524515614
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

TCERG1L MYH7B SYNE1 LAMP5 OGFOD3 ODF2 GPR101 ABCB4 EEF1A2 ADAMTS12 BPTF STARD9 RBMX2 ATP11C MPHOSPH8 ATM ATP2A2 BAHCC1

1.02e-0514421331835575683
Pubmed

53BP1 depletion causes PARP inhibitor resistance in ATM-deficient breast cancer cells.

ATM TP53BP1

1.45e-052133227613518
Pubmed

ATM and 53BP1 regulate alternative end joining-mediated V(D)J recombination.

ATM TP53BP1

1.45e-052133239083600
Pubmed

53BP1 is limiting for NHEJ repair in ATM-deficient model systems that are subjected to oncogenic stress or radiation.

ATM TP53BP1

1.45e-052133223858098
Pubmed

TBCD may be a causal gene in progressive neurodegenerative encephalopathy with atypical infantile spinal muscular atrophy.

TBCD BAHCC1

1.45e-052133227928163
Pubmed

Phosphorylation of the DNA damage repair factor 53BP1 by ATM kinase controls neurodevelopmental programs in cortical brain organoids.

ATM TP53BP1

1.45e-052133239226322
Pubmed

Negative cell cycle regulation and DNA damage-inducible phosphorylation of the BRCT protein 53BP1.

ATM TP53BP1

1.45e-052133211042216
Pubmed

S1219 residue of 53BP1 is phosphorylated by ATM kinase upon DNA damage and required for proper execution of DNA damage response.

ATM TP53BP1

1.45e-052133218996087
Pubmed

The role of ATM and 53BP1 as predictive markers in cervical cancer.

ATM TP53BP1

1.45e-052133222323184
Pubmed

Normal myoblast fusion requires myoferlin.

TRIM33 MYOF

1.45e-052133216280346
Pubmed

53BP1, an activator of ATM in response to DNA damage.

ATM TP53BP1

1.45e-052133215279780
Pubmed

Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment.

CALCA NRG2 SSTR2 GRM7 BDKRB1 CNTN3 PLCB4 CNTN2

2.15e-05300133819086053
Pubmed

DNA damage-induced G2-M checkpoint activation by histone H2AX and 53BP1.

ATM TP53BP1

4.34e-053133212447390
Pubmed

Vaccinia-related kinase 1 (VRK1) is an upstream nucleosomal kinase required for the assembly of 53BP1 foci in response to ionizing radiation-induced DNA damage.

ATM TP53BP1

4.34e-053133222621922
Pubmed

Overlapping and differential expression of BIG-2, BIG-1, TAG-1, and F3: four members of an axon-associated cell adhesion molecule subgroup of the immunoglobulin superfamily.

CNTN3 CNTN2

4.34e-05313328586965
Pubmed

ATM Localization and Heterochromatin Repair Depend on Direct Interaction of the 53BP1-BRCT2 Domain with γH2AX.

ATM TP53BP1

4.34e-053133226628370
Pubmed

Role of ATM and the damage response mediator proteins 53BP1 and MDC1 in the maintenance of G(2)/M checkpoint arrest.

ATM TP53BP1

4.34e-053133220421415
Pubmed

Protein-protein interactions occur between p53 phosphoforms and ATM and 53BP1 at sites of exogenous DNA damage.

ATM TP53BP1

4.34e-053133221361779
Pubmed

A complex containing the CPSF73 endonuclease and other polyadenylation factors associates with U7 snRNP and is recruited to histone pre-mRNA for 3'-end processing.

CASP8AP2 CPSF3

4.34e-053133223071092
Pubmed

Roles of the DOCK-D family proteins in a mouse model of neuroinflammation.

DOCK9 DOCK10

4.34e-053133232241915
Pubmed

53BP1 and NFBD1/MDC1-Nbs1 function in parallel interacting pathways activating ataxia-telangiectasia mutated (ATM) in response to DNA damage.

ATM TP53BP1

4.34e-053133214695167
Pubmed

Accumulation of checkpoint protein 53BP1 at DNA breaks involves its binding to phosphorylated histone H2AX.

ATM TP53BP1

4.34e-053133212697768
Pubmed

A DNA damage-regulated BRCT-containing protein, TopBP1, is required for cell survival.

ATM TP53BP1

4.34e-053133211756551
Pubmed

ATMIN is required for the ATM-mediated signaling and recruitment of 53BP1 to DNA damage sites upon replication stress.

ATM TP53BP1

4.34e-053133225262557
Pubmed

The DNA sequence and analysis of human chromosome 13.

COL4A2 DOCK9 GPC6 SPRYD7 SLITRK5 MPHOSPH8

5.13e-05170133615057823
Pubmed

Human gingiva transcriptome during wound healing.

COL4A2 CD163 ADAMTS12 CD300LB ADAMTS15

5.90e-05107133528005267
Pubmed

Proteomic analysis of exosomes from human neural stem cells by flow field-flow fractionation and nanoflow liquid chromatography-tandem mass spectrometry.

SRSF7 ARHGEF18 TXNRD1 BPTF

5.99e-0555133418570454
Pubmed

Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

SEMA4B ITGB2 CD163 JAM2 ASAH1 CNTN3 CNTN2

6.25e-05257133716335952
Pubmed

c-Abl kinase is required for beta 2 integrin-mediated neutrophil adhesion.

ITGB2 TLN2

8.67e-054133219234221
Pubmed

Human PTIP facilitates ATM-mediated activation of p53 and promotes cellular resistance to ionizing radiation.

ATM TP53BP1

8.67e-054133215456759
Pubmed

Dual interaction of JAM-C with JAM-B and alpha(M)beta2 integrin: function in junctional complexes and leukocyte adhesion.

ITGB2 JAM2

8.67e-054133216093349
Pubmed

Low levels of endogenous or X-ray-induced DNA double-strand breaks activate apoptosis in adult neural stem cells.

ATM TP53BP1

8.67e-054133226303202
Pubmed

TRIM24 is a p53-induced E3-ubiquitin ligase that undergoes ATM-mediated phosphorylation and autodegradation during DNA damage.

TRIM33 ATM

8.67e-054133224820418
Pubmed

Mammalian Rif1 contributes to replication stress survival and homology-directed repair.

ATM TP53BP1

8.67e-054133219948482
Pubmed

A pathway of double-strand break rejoining dependent upon ATM, Artemis, and proteins locating to gamma-H2AX foci.

ATM TP53BP1

8.67e-054133215574327
Pubmed

ATR and ATM-dependent movement of BLM helicase during replication stress ensures optimal ATM activation and 53BP1 focus formation.

ATM TP53BP1

8.67e-054133215539948
Pubmed

Essential role for DNA-PKcs in DNA double-strand break repair and apoptosis in ATM-deficient lymphocytes.

ATM TP53BP1

8.67e-054133219450527
Pubmed

53BP1 loss induces chemoresistance of colorectal cancer cells to 5-fluorouracil by inhibiting the ATM-CHK2-P53 pathway.

ATM TP53BP1

8.67e-054133227838786
Pubmed

DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation.

ATM TP53BP1

8.67e-054133212556884
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

SEMA4B BCAS3 ARHGAP26 DOCK9 ATG2A ADGRA2 MYOF ARVCF CSAD TLN2 HECTD1 GCN1 TBCD BAHCC1

9.02e-0511051331435748872
Pubmed

The receptor guanylyl cyclase Npr2 is essential for sensory axon bifurcation within the spinal cord.

CALCA GUCY1A1 CNTN2

9.15e-0523133317954614
Pubmed

Systematic identification of molecular links between core and candidate genes in breast cancer.

BCAS3 ADGRB1 EEF1A2 GLCE FECH ATM

1.06e-04194133625640309
Pubmed

The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.

SEMA4B LAYN TMC2 CYP2S1 GPC6 JAM2 ADAMTS12 OIT3 BTNL3 CD300LB HSD17B13 LRRC8A IPO11

1.09e-049851331312975309
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

SEMA4B ARHGEF18 TOGARAM1 MYOF KRBA1 SH3GLB1 GLCE SLITRK5 HECTD1

1.24e-04493133915368895
Pubmed

SHLD1 is dispensable for 53BP1-dependent V(D)J recombination but critical for productive class switch recombination.

ATM TP53BP1

1.44e-045133235764636
Pubmed

ATM prevents the persistence and propagation of chromosome breaks in lymphocytes.

ATM TP53BP1

1.44e-045133217599403
Pubmed

Metalloproteinase Adamts16 Is Required for Proper Closure of the Optic Fissure.

ADAMTS12 ADAMTS15

1.44e-045133229625437
Pubmed

Differential requirement for H2AX and 53BP1 in organismal development and genome maintenance in the absence of poly(ADP)ribosyl polymerase 1.

ATM TP53BP1

1.44e-045133220231360
Pubmed

Requirement for DNA ligase IV during embryonic neuronal development.

ATM TP53BP1

1.44e-045133221734301
Pubmed

Zizimin2: a novel, DOCK180-related Cdc42 guanine nucleotide exchange factor expressed predominantly in lymphocytes.

DOCK9 DOCK10

1.44e-045133215710388
Pubmed

DNA double-strand break response factors influence end-joining features of IgH class switch and general translocation junctions.

ATM TP53BP1

1.44e-045133229311308
Pubmed

ATM and CDK2 control chromatin remodeler CSB to inhibit RIF1 in DSB repair pathway choice.

ATM TP53BP1

1.44e-045133229203878
Pubmed

53BP1 mediates the fusion of mammalian telomeres rendered dysfunctional by DNA-PKcs loss or inhibition.

ATM TP53BP1

1.44e-045133225264618
Pubmed

53BP1 promotes non-homologous end joining of telomeres by increasing chromatin mobility.

ATM TP53BP1

1.44e-045133218931659
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

UBR1 SRSF7 ODF2 BPTF MYOF BRD8 RBMX2 TLN2 ATM ATP2A2 TP53BP1

2.00e-047741331115302935
Pubmed

O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.

ADGRB1 THSD7B ADAMTS12 ADAMTS15

2.01e-0475133420637190
Pubmed

SUMOylation of DDX39A Alters Binding and Export of Antiviral Transcripts to Control Innate Immunity.

LAYN MYH7B NRG2 PDZD7 SIRT5 ABCB4 JAM2 PTPN2 NUDT3 FECH TLN2 TRIM16L

2.14e-049151331232393512
Pubmed

Differential effects of HTLV-1 Tax oncoprotein on the different estrogen-induced-ER α-mediated transcriptional activities.

CNTN2 TP53BP1

2.16e-046133227420286
Pubmed

The proximity ligation assay reveals that at DNA double-strand breaks WRAP53β associates with γH2AX and controls interactions between RNF8 and MDC1.

ATM TP53BP1

2.16e-046133226734725
Pubmed

A selective requirement for 53BP1 in the biological response to genomic instability induced by Brca1 deficiency.

ATM TP53BP1

2.16e-046133219716796
Pubmed

The RhoGEF DOCK10 is essential for dendritic spine morphogenesis.

DOCK9 DOCK10

2.16e-046133225851601
Pubmed

New gene functions in megakaryopoiesis and platelet formation.

ARVCF FEN1 HSD17B13 EXOC3L2

2.71e-0481133422139419
Pubmed

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.

BCAS3 SYNE1 PDZD7 STARD9 PCDH11X NUB1

2.86e-04233133637704626
Pubmed

Orientation-specific joining of AID-initiated DNA breaks promotes antibody class switching.

ATM TP53BP1

3.01e-047133226308889
Pubmed

Elevated lung cancer risk is associated with deficiencies in cell cycle checkpoints: genotype and phenotype analyses from a case-control study.

ATM TP53BP1

3.01e-047133219626602
Pubmed

BRIT1 regulates early DNA damage response, chromosomal integrity, and cancer.

ATM TP53BP1

3.01e-047133216872911
Pubmed

ATM-phosphorylated SPOP contributes to 53BP1 exclusion from chromatin during DNA replication.

ATM TP53BP1

3.01e-047133234144977
Pubmed

A single synonymous mutation determines the phosphorylation and stability of the nascent protein.

ATM TP53BP1

3.01e-047133230252118
Pubmed

Analysis of the factors involved in the retinoic acid-induced differentiation of a retinoid-hypersensitive embryonal carcinoma cell mutant.

COL4A2 CRABP1

3.01e-04713328299717
Pubmed

HectD1 controls hematopoietic stem cell regeneration by coordinating ribosome assembly and protein synthesis.

TTC28 FECH HECTD1 GCN1

3.56e-0487133433711283
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

TTC28 HECTD3 SIRT5 BRWD3 TRIM33 RSBN1 BPTF TCHH BRD8 FECH CRNN TIGD5 BAHCC1

3.65e-0411161331331753913
Pubmed

53BP1 promotes ATM activity through direct interactions with the MRN complex.

ATM TP53BP1

4.00e-048133220010693
Pubmed

Variants in TNFAIP3, STAT4, and C12orf30 loci associated with multiple autoimmune diseases are also associated with juvenile idiopathic arthritis.

RSBN1 PTPN2

4.00e-048133219565500
Pubmed

β2 integrin adhesion complexes maintain the integrity of HIV-1 assembly compartments in primary macrophages.

ITGB2 TLN2

4.00e-048133222017400
Pubmed

ATM and PRDM9 regulate SPO11-bound recombination intermediates during meiosis.

ATM TP53BP1

4.00e-048133232051414
Pubmed

An SH3 domain-containing GTPase-activating protein for Rho and Cdc42 associates with focal adhesion kinase.

ARHGAP26 ITGB2

4.00e-04813328649427
Pubmed

The role of Hoxa-3 in mouse thymus and thyroid development.

CALCA CRABP1

4.00e-04813327635047
Pubmed

A mouse knockout library for secreted and transmembrane proteins.

LAYN TMC2 GPC6 ADAMTS12 OIT3 CD300LB HSD17B13 LRRC8A

4.09e-04460133820562862
Pubmed

Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion.

SEMA4B ADGRA2 JAM2 CNTN3 CNTN2

4.10e-04162133525826454
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

TTC28 CEP85L SYNE1 ODF2 BRWD3 EEF1A2 SPRYD7 ZNF7 TRIM33 TLN2 ZNF528 ATM HECTD1 ATP2A2

4.22e-0412851331435914814
Pubmed

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.

TTC28 WNT8A TRIM33 BPTF ABHD16B INTS2 GCN1 TP53BP1

4.65e-04469133827634302
Pubmed

Diverse spinal commissural neuron populations revealed by fate mapping and molecular profiling using a novel Robo3Cre mouse.

CALCA LAMP5 CNTN2

4.87e-0440133331152445
Pubmed

Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity.

UBR1 HECTD3 TRIM33 HECTD1

4.97e-0495133429643511
Pubmed

The histone demethylase LSD1/KDM1A promotes the DNA damage response.

ATM TP53BP1

5.13e-049133224217620
Pubmed

A genome-wide scan for breast cancer risk haplotypes among African American women.

BCAS3 GRM7

5.13e-049133223468962
Pubmed

Altered segmental identity and abnormal migration of motor neurons in mice lacking Hoxb-1.

WNT8A CRABP1

5.13e-04913328967950
Pubmed

Small molecule inhibitors uncover synthetic genetic interactions of human flap endonuclease 1 (FEN1) with DNA damage response genes.

FEN1 ATM

5.13e-049133228628639
Pubmed

The tripartite motif family identifies cell compartments.

TRIM39 TRIM33 TRIM16L

5.24e-0441133311331580
Pubmed

Generation and analysis of 280,000 human expressed sequence tags.

HECTD3 ADAMTS12 RSBN1 CAVIN4 ASAH1 GLCE EXOC3L2

5.58e-0436813378889549
Pubmed

Transcription factor Foxp3 and its protein partners form a complex regulatory network.

NIBAN1 RSBN1 BPTF RBMX2 FEN1 ATM GCN1

5.76e-04370133722922362
Pubmed

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.

HJV SEMA4B TMEM151B BRD8 INTS2 GLCE FECH MPHOSPH8 CHCHD1 METTL16 EXOC3L2 HECTD1 GCN1 MTMR9

5.79e-0413271331432694731
Pubmed

Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.

GPR101 GRM7 ITGB2 SLITRK5

6.26e-04101133423382219
Pubmed

A Damage-Independent Role for 53BP1 that Impacts Break Order and Igh Architecture during Class Switch Recombination.

ATM TP53BP1

6.40e-0410133227320916
Pubmed

The hot-spot p53R172H mutant promotes formation of giant spermatogonia triggered by DNA damage.

ATM TP53BP1

6.40e-0410133227869164
Pubmed

Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

MYH7B ADGRA2 CNTN3 BAHCC1

6.74e-04103133410819331
Pubmed

Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

TTC28 DOCK9 PPM1E TRIM33

6.99e-04104133410470851
Pubmed

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.

UBR1 SRSF7 MUC5B TXNRD1 PTPN2 MYOF ASAH1 FEN1 ATP2A2 GCN1 CPSF3 TP53BP1 TBCD IPO11

7.73e-0413671331432687490
Pubmed

MDC1 is a mediator of the mammalian DNA damage checkpoint.

ATM TP53BP1

7.80e-0411133212607005
InteractionSEM1 interactions

UBR1 EEF1A2 TXNRD1 TRIM33 INTS2 FEN1 TLN2 NUB1 HECTD1

1.30e-061621339int:SEM1
Cytoband2q36.2

DOCK10 FAM124B

2.53e-05313422q36.2
Cytoband15q15-q21

TLN2 TP53BP1

5.05e-054134215q15-q21
GeneFamilyFerlin family

MYOF FER1L4

3.47e-046882828
GeneFamilyEF-hand domain containing|S100 fused type protein family

TCHH CRNN

4.84e-0478821350
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_top-relative-expression-ranked_500

NIBAN1 CALCA GPC6 GRM7 TMEM132C RSBN1 GUCY1A1 PCDH11X ADAMTS15 TLN2 ATP11C GCN1

8.07e-0640813012DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_500
ToppCellEndothelial-A-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

COL4A2 CRABP1 ADGRA2 BDKRB1 JAM2 PLCB4 EXOC3L2 FAM124B

1.11e-07189134804b565855f58ca0f343904d04be657b66e109076
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SYNE1 DOCK10 ADGRA2 TMEM132C STARD9 CNTN3 ATP11C

6.69e-071641347f6a961fa2002da7d9679f32af99e1314c0593ef9
ToppCellnormal-na-Lymphocytic_NK-NK_bright-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

SRSF7 SYNE1 ITGB2 PTPN2 GARIN4 ATM MCTP2

6.69e-071641347b5a91f2cbfad9a2bc38aea576085a37865df955d
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NIBAN1 CEP85L SYNE1 ADGRA2 TMEM132C CNTN3 ATP11C

8.52e-071701347876b84740e15399bfff2b9c7f0b80fd759bbdb3f
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NIBAN1 CEP85L SYNE1 ADGRA2 TMEM132C CNTN3 ATP11C

8.52e-0717013471f8738acf439d893880db7e1fdc9b3615ca00c39
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SYNE1 DOCK10 ADGRA2 TMEM132C STARD9 CNTN3 ATP11C

9.21e-07172134708a3fe536b1b064c5ee7779bc2b1115a5963a26b
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SYNE1 DOCK10 ADGRA2 TMEM132C STARD9 CNTN3 ATP11C

9.21e-071721347553701349444eb366df3c11f54bb093434f153c6
ToppCell(4)_Endothelial_cells-(40)_EC-arterial|(4)_Endothelial_cells / Cell class and subclass of bone marrow stroma cells in homeostatis

NIBAN1 SYNE1 JAM2 MYOF GUCY1A1 TLN2 PLCB4

1.79e-061901347ff774faf3f12759d11e50ed7d189288bb79e22e1
ToppCellfacs-Lung-Endomucin_-18m|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CEP85L SYNE1 DOCK9 MYZAP JAM2 LRRC8A FAM124B

1.92e-061921347ba3fe97786564dba1c8185f2802ce1b57f4f3cc9
ToppCellfacs-Lung-Endomucin_|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CEP85L SYNE1 DOCK9 MYZAP JAM2 LRRC8A FAM124B

1.92e-06192134785d4d0df701451daf95e94a87a0096da1e86533b
ToppCelldroplet-Liver-LIVER_HEP-30m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A2 TTC28 MYZAP ADGRA2 JAM2 PPP1R3A OIT3

1.99e-061931347826b8dd801298b3e0cd76232feae5a14026b8806
ToppCelldroplet-Liver-LIVER_HEP-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A2 TTC28 MYZAP ADGRA2 JAM2 PPP1R3A OIT3

1.99e-06193134787d3a577d37fb0cb4b6313c596310de452bc3872
ToppCelldroplet-Liver-LIVER_HEP-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A2 TTC28 MYZAP ADGRA2 JAM2 PPP1R3A OIT3

1.99e-061931347d485634c564b268e344b6a2863c26f6adaec9e38
ToppCellfacs-Lung-Endomucin_-18m-Endothelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CEP85L SYNE1 DOCK9 MYZAP JAM2 LRRC8A FAM124B

2.06e-061941347df56e23f1dcf1902d29392fcc947e0e268e1648b
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TTC28 ARHGAP26 DOCK9 JAM2 STARD9 EXOC3L2 TBCD

2.20e-061961347b8f89a50114932c08fc5daac4b549adfe9df8e66
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TTC28 ARHGAP26 DOCK9 JAM2 STARD9 EXOC3L2 TBCD

2.20e-061961347145fcf73deba9638b391a1af6c39fa205dc9829f
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

COL4A2 SYNE1 ADAMTS12 TMEM132C MYOF SLITRK5 ADAMTS15

2.43e-06199134730d3e8c0681ec11f86dd38c5f48d21187a1b4f90
ToppCellLPS_IL1RA-Endothelial-Endothelial-Activated_Alv_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

COL4A2 CEP85L DOCK9 MYZAP JAM2 GUCY1A1 NUB1

2.52e-06200134779e51afb57ca38aacebd0298e5e727b55c0cfff9
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

COL4A2 DOCK9 MYZAP ABCB4 JAM2 PLCB4 FAM124B

2.52e-062001347a1fa6bae5a688faf488d6925cd3fad725dfa916b
ToppCellLPS_IL1RA_TNF-Endothelial|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

COL4A2 DOCK9 MYZAP ABCB4 JAM2 PLCB4 FAM124B

2.52e-062001347d01cec331be3b03cef80e9536fc531285bcf00f6
ToppCellfacs-Trachea-nan-3m-Myeloid-lymphocyte_of_B_lineage|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA4B TMEM151B ARHGEF18 ABCB4 TIGD5 MCTP2

8.15e-0615713460fecc14959c4c9efc19d5c06475a890e0a30f148
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CEP85L SYNE1 ADGRA2 TMEM132C CNTN3 ATP11C

8.76e-0615913465ca96db4281abb5f646150ccf36adc66ab201c78
ToppCell367C-Lymphocytic-ILC-ILC-3|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

SEMA4B BCAS3 NRG2 ZNF7 TRIM16L TBCD

9.41e-0616113468de421c61f4d5a6e05fdb20e4d230e2db98ee4d5
ToppCellwk_08-11-Mesenchymal-Myofibro_&_SMC-Late_airway_SMC|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

COL4A2 PDZD7 THSD7B TECTA STARD9 CSAD

1.01e-0516313461e8730d75cccf7292010683ab4e81a69d8e3bfa9
ToppCellTCGA-Head_and_Esophagus-Solid_Tissue_Normal-Head_and_Neck-Head_and_Neck_normal_tissue-6|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9

HJV KLHL40 GPR101 MYZAP PPP1R3A CRNN

1.16e-0516713464a533972a0f40fff82dccf8e64716cb34f75736e
ToppCellAdult-Mesenchymal-vascular_smooth_muscle_cell|Adult / Lineage, Cell type, age group and donor

COL4A2 SSTR2 GPC6 ADGRA2 GUCY1A1 PLCB4

1.37e-051721346c62cad0f4212d1e9ea1ec3143ad3c4e06aff0ebf
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NIBAN1 GPC6 ADAMTS12 TYMS GUCY1A1 LRRC8A

1.42e-0517313465c55e1e27e9e3e77600d378cc87b51cc73907527
ToppCellfacs-Heart-RV-24m-Mesenchymal-ventricular_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EEF1A2 PPP1R3A CAVIN4 SLITRK5 CRNN ATP2A2

1.61e-051771346692cd03bf0958ebeec34d41bfe87713a768e9a8e
ToppCellfacs-Heart-RV-24m-Mesenchymal-ventricular_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EEF1A2 PPP1R3A CAVIN4 SLITRK5 CRNN ATP2A2

1.61e-051771346c08583ea68bbeb6b5de852a46b0c0f04792dae55
ToppCell(5)_Glands_mucous|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

MUC5B GARIN4 GUCY1A1 SLITRK5 CNTN3 PLCB4

1.66e-051781346f0f19b0d78f2cc5df4d4c321a953a6e447d5114a
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_A-Branch_A4_(IN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TMEM151B PPM1E SSTR2 CRABP1 EEF1A2 ARVCF

1.89e-051821346be32b5b8153c1053cbb55f1fccfa27c3ee97c1e1
ToppCelldroplet-Liver-HEPATOCYTES-1m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A2 LAYN ODF2 JAM2 OIT3 PLCB4

2.07e-051851346742350093d90f96735dc73e3360cdd749bae63fd
ToppCellhuman_hepatoblastoma-Hepatic_Stellate_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

COL4A2 NIBAN1 ADGRA2 ADAMTS12 MYOF GUCY1A1

2.13e-051861346cb1fc4b9140666b43415e21c9b434dc9b144e9d0
ToppCellControl-Endothelial_cells-Endothelial_cells_(other)|Control / group, cell type (main and fine annotations)

COL4A2 TTC28 ARHGAP26 DOCK9 JAM2 PLCB4

2.13e-051861346c6075fe84226b370c5139066793844ad33ae2db1
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NIBAN1 THSD7B ADGRA2 GUCY1A1 STARD9 PLCB4

2.20e-05187134648bfdb3504c3fefe5db3abac4b790c369680ab4e
ToppCellRV-07._Pericyte|World / Chamber and Cluster_Paper

THSD7B SSTR2 ADGRA2 ADAMTS12 GUCY1A1 PLCB4

2.20e-051871346dc274d6bbda619a2c914d84e2b4069cfef1739d1
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SYNE1 DOCK10 ADGRA2 TMEM132C STARD9 ATP11C

2.20e-05187134615d6e158562d7d85af3ceaf955439b379c8fce81
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SYNE1 DOCK10 ADGRA2 TMEM132C STARD9 ATP11C

2.20e-051871346f62074b631fd45ad299c69d71b09267b04d656ee
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NIBAN1 THSD7B ADGRA2 GUCY1A1 STARD9 PLCB4

2.20e-051871346958402fcc78f4c7a7d13d659d776f3817137975f
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L5-6_LAMP5_SFTA3_(Lamp5_Lhx6_2)|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COL4A2 DOCK10 LAMP5 THSD7B CRABP1 ATP11C

2.26e-0518813468268574584e5fb869a6cb8bbd7135cd7454a6a25
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SYNE1 DOCK10 ADGRA2 TMEM132C STARD9 ATP11C

2.26e-05188134632f22a4d8cb98fd8b8fa0fbf28ef9266d711d081
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-skeletal_muscle_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HJV KLHL40 ABCB4 EEF1A2 PPP1R3A CAVIN4

2.33e-051891346d2b008f98739c6af7ee63b643011a240db20e4d8
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COL4A2 DOCK10 LAMP5 THSD7B JAM2 ATP11C

2.40e-05190134656cc761e50fddfb5366391518b4d8e16589b6b42
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L5-6_LAMP5_SFTA3_(Lamp5_Lhx6_2)|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COL4A2 DOCK10 LAMP5 THSD7B CRABP1 ATP11C

2.40e-05190134659720dfe9de1b980807644536c919d2a02ba69dd
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COL4A2 DOCK10 LAMP5 THSD7B JAM2 ATP11C

2.40e-05190134625d4b591f75c26e404a34c42f1742d580af6598d
ToppCellhuman_hepatoblastoma-Hepatic_Stellate_cells|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)

COL4A2 NIBAN1 ADGRA2 ADAMTS12 MYOF GUCY1A1

2.47e-05191134678c3c2fdb68c3407f2436f90e1e6a780bbf8b79e
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COL4A2 DOCK10 LAMP5 THSD7B CRABP1 ATP11C

2.55e-051921346f6ec683b2133b3095a1fcc06ca8605cf38f774b5
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NIBAN1 GPC6 ADAMTS12 GUCY1A1 ADAMTS15 PLCB4

2.55e-05192134626d9207e72bbef5e0046de511e2c9ff752b726f3
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-4_LAMP5_DUSP4_(Lamp5_Rosehip)|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COL4A2 DOCK10 LAMP5 THSD7B JAM2 ATP11C

2.55e-051921346342842378c20267c5044bdd622515e8b9f895623
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COL4A2 DOCK10 LAMP5 THSD7B CRABP1 ATP11C

2.55e-051921346690b3d17c481159bc96b8bc7f6a66b51343ee858
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COL4A2 DOCK10 LAMP5 CRABP1 JAM2 ATP11C

2.62e-051931346294cb5b580bb83fe0eb04f112d5507aac35d4d44
ToppCellfacs-Lung-Endomucin_-18m-Endothelial-endothelial_cell_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CEP85L SYNE1 DOCK9 MYZAP LRRC8A FAM124B

2.62e-0519313462218833749576ba1a0fc95bd155c781e7e1163c6
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NIBAN1 GPC6 ADAMTS12 GUCY1A1 ADAMTS15 PLCB4

2.62e-0519313467fc3ab7261c88c1df71744bf5b17e8e46c4300e0
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COL4A2 DOCK10 LAMP5 CRABP1 JAM2 ATP11C

2.62e-0519313463d3c45d5ff6f3396a1990615aae9fe176e799994
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COL4A2 DOCK10 LAMP5 CRABP1 JAM2 ATP11C

2.70e-05194134652aebb0b563e2c2058e7f0554ae870e47692b163
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COL4A2 DOCK10 LAMP5 THSD7B JAM2 ATP11C

2.70e-0519413466ac759828c41ffa974ee82842162caa959351dd1
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

TTC28 DOCK10 ADAMTS12 TMEM132C GUCY1A1 GLCE

2.70e-051941346b1bb0f846d2865efdd9bc8842b16b9d069785882
ToppCellfacs-Lung-Endomucin_-18m-Endothelial-Capillary_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CEP85L DOCK9 MYZAP JAM2 LRRC8A FAM124B

2.70e-051941346e30a3765feae5cd10ddba16a166c31eb5717edd3
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-SMC_prolif-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

COL4A2 ADGRA2 ADAMTS12 TYMS MYOF GUCY1A1

2.70e-05194134678dcb9d48259afabe73b41c5508a73a8d62339a4
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COL4A2 DOCK10 LAMP5 THSD7B JAM2 ATP11C

2.70e-0519413465d0b0d8e96f0e0297a4dba70a05d87081a4eb323
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COL4A2 DOCK10 LAMP5 CRABP1 JAM2 ATP11C

2.70e-051941346bd06e2b8d8c06cddf2e4f58849b86e09013acae1
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

TTC28 DOCK10 ADAMTS12 TMEM132C GUCY1A1 GLCE

2.78e-0519513460e55fa5b3cbeb7baee3d4ac272a3bf80381ec937
ToppCellBronchial-NucSeq-Epithelial-Epi_submucosal-gland-Myoepithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL4A2 ADGRB1 NRG2 GPC6 PLCB4 ATP2A2

2.86e-051961346a58bdf9de05d13d84211e09a933679d485bf8ab4
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TTC28 ARHGAP26 DOCK9 STARD9 EXOC3L2 TBCD

2.86e-051961346d0ff1082898d2db47c88d2678466514e9e9193d3
ToppCellPCW_13-14-Mesenchymal|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

TTC28 DOCK10 GPC6 ADAMTS12 TMEM132C GUCY1A1

2.94e-05197134673a2085d2682d636726a5432d572ae2a3fbe1c3f
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

DOCK10 GPC6 ADAMTS12 TMEM132C GUCY1A1 CNTN3

2.94e-05197134611a4c417f035e554431a8f03be13b5eefa3530c0
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SYNE1 ARHGAP26 DOCK9 JAM2 EXOC3L2 TBCD

3.03e-051981346451003a21162eeae90739fdb502bb50b362d80c8
ToppCellTracheal-NucSeq-Immune_Myeloid-Dendritic_cell-DC_2|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DOCK10 ITGB2 CD163 ABCB4 CD300LB FEN1

3.03e-051981346d73585a5587941483db8d9ddc2d68f7d852bbbc8
ToppCellmetastatic_Brain-Endothelial_cells|metastatic_Brain / Location, Cell class and cell subclass

COL4A2 LAYN ADGRA2 JAM2 EXOC3L2 IPO11

3.03e-05198134697ef7946ef11ac93318c1dd46b548dc01e5a6aba
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SYNE1 ARHGAP26 DOCK9 JAM2 EXOC3L2 TBCD

3.03e-051981346440af8f90c7afa1c07000806bcf9110b70f489fb
ToppCellmetastatic_Brain-Endothelial_cells-Tumor_ECs|metastatic_Brain / Location, Cell class and cell subclass

COL4A2 LAYN ADGRA2 JAM2 EXOC3L2 IPO11

3.03e-0519813465e274f29cc796dae7d64d6035e904816c25f9914
ToppCellTracheal-NucSeq-Stromal-Peri/Epineurial_|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL4A2 GPC6 JAM2 ADAMTS12 TMEM132C STARD9

3.11e-0519913463835452e4848d7f7dd8651c17b746b271ef39688
ToppCellLPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

SYNE1 ADAMTS12 TMEM132C MYOF PCDH11X MCTP2

3.11e-0519913466b3a0e5d52a30d0eed30e6a670f5b53bc233f70c
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

SYNE1 ADAMTS12 TMEM132C MYOF SLITRK5 ADAMTS15

3.20e-0520013469b0916d8d07ac2bf1739f7be5296bf77ffee6094
ToppCellLPS_anti-TNF-Endothelial-Endothelial-Activated_Alv_Cap|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

COL4A2 CEP85L DOCK9 MYZAP JAM2 LRRC8A

3.20e-052001346bcd1cc96197929d6011903803b6f4ccdcf52b4ce
ToppCellLPS_only-Endothelial-Endothelial-Activated_Alv_Cap|LPS_only / Treatment groups by lineage, cell group, cell type

COL4A2 CEP85L DOCK9 MYZAP ABCB4 NUB1

3.20e-052001346edb64556b3fefe3144f73b6efe23b9ffd34091d2
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-Activated_Alv_Cap|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

COL4A2 DOCK9 MYZAP JAM2 GUCY1A1 NUB1

3.20e-05200134689821a264e872ed53e08e9d3609d5cc5c314503e
ToppCellControl_saline-Endothelial-Endothelial-Gen_Cap|Control_saline / Treatment groups by lineage, cell group, cell type

COL4A2 DOCK9 ABCB4 BPTF PLCB4 FAM124B

3.20e-0520013463b97920e1e6e2f09ddba2a861baa9c00c2970f4c
ToppCellControl_saline-Endothelial-Endothelial|Control_saline / Treatment groups by lineage, cell group, cell type

COL4A2 DOCK9 MYZAP JAM2 SH3GLB1 PLCB4

3.20e-052001346e77eba6172cabf85b8028638ed35299f2f079cd8
ToppCellLPS_anti-TNF-Endothelial|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

COL4A2 DOCK9 MYZAP JAM2 PLCB4 FAM124B

3.20e-0520013461d105eeda5a2c51f9a4654ffc79b7e2348ad593b
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

COL4A2 DOCK9 JAM2 BPTF PLCB4 FAM124B

3.20e-052001346b2d4e6f3e8e4da62e6b02758ab2ed8f505269f9a
ToppCellLPS_anti-TNF-Endothelial-Endothelial|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

COL4A2 DOCK9 MYZAP JAM2 PLCB4 FAM124B

3.20e-05200134660d2cbf41f37f1b11eddb4c9d9246c9c1fc5a5af
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Neuronal-Neuron|10w / Sample Type, Dataset, Time_group, and Cell type.

DOCK10 LAMP5 SSTR2 CRABP1 CD163 CNTN2

3.20e-052001346332905a686356cd1e024d40679be98e9d8b1b5e8
ToppCellControl_saline-Endothelial|Control_saline / Treatment groups by lineage, cell group, cell type

COL4A2 DOCK9 MYZAP JAM2 SH3GLB1 PLCB4

3.20e-0520013463372c488a39fe812fa94e4f0564594186fea3db5
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|367C / Donor, Lineage, Cell class and subclass (all cells)

TCERG1L KRBA1 ADAMTS15 ZNF528 ATM

4.79e-051311345cc5b5afab8622e98f673fa116a226d930c295327
ToppCell356C-Fibroblasts-Fibroblast-C_(Myofibroblast)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

COL4A2 PPM1E TMEM132C PCDH11X MCTP2

7.03e-0514213457b6678a73d04feac12bbc909f2df478215511de0
ToppCell356C-Fibroblasts-Fibroblast-C_(Myofibroblast)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

COL4A2 PPM1E TMEM132C PCDH11X MCTP2

7.03e-051421345347f5832a86f4e41752e36e3e737df7ca6f79e90
ToppCellE18.5-samps-Mesenchymal-Pericyte-pericyte_C|E18.5-samps / Age Group, Lineage, Cell class and subclass

HJV ADAM21 SSTR2 GUCY1A1 MTMR9

9.39e-0515113453f2abaa42876ce7a71d934ff16abe0cab0991a05
ToppCellfacs-Aorta-Heart-3m-Mesenchymal-valve_cells|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HJV LAMP5 CRABP1 PPP1R3A GUCY1A1

9.99e-0515313451440f2716fea74e2c3eb2924eba3d63ebd08c997
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell_prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK9 BTNL3 STARD9 PCDH11X FAM124B

1.03e-041541345e51a5114f0ec38f997f5b8bbf3a7770f98595474
ToppCell21-Trachea-Epithelial-Submucosal_gland_basal|Trachea / Age, Tissue, Lineage and Cell class

COL4A2 ADGRB1 LAMP5 THSD7B CRABP1

1.20e-0415913454f670b57b8d3b090ea2f1aafe15baf93cb7ef146
ToppCellCOVID-19-kidney-Technical/muscle_(Imm)|kidney / Disease (COVID-19 only), tissue and cell type

HJV TCERG1L THSD7B GRM7 TMEM132C

1.34e-04163134519c28ce16a588a7f4a035c32726f6ccd67702b5b
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

TCERG1L LAMP5 KRBA1 ADAMTS15 ZNF528

1.34e-04163134563b0badaee3b2d827b1f4524510e3384d8f8fcde
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_bronchial_vessel|Children_(3_yrs) / Lineage, Cell type, age group and donor

COL4A2 JAM2 KCTD3 PLCB4 EXOC3L2

1.34e-041631345977a970b1296234c22178420294cea73506ee02f
ToppCellPND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T-CD8_T_prolif|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CASP8AP2 ODF2 TYMS RBMX2 FEN1

1.38e-0416413455621c2e3fae84d5a2e4f1595e454bcb3a2b3f93c
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TRIM39 MUC5B GPC6 ARVCF BAHCC1

1.46e-04166134560060b03f2abfa3cc08107ab5a9f578e60e4ae16
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TRIM39 MUC5B GPC6 ARVCF BAHCC1

1.46e-041661345ec9161d388db5a257b8d125c14f9dd911d5d5d4a
ToppCell3'-Adult-LargeIntestine-Epithelial-mature_enterocytic-Paneth|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CRABP1 RSBN1 ARVCF PCDH11X CPSF3

1.46e-041661345b64ab3d13b76bba3c305ebbfc96f983cd6ca30c9
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)-|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TRIM39 MUC5B GPC6 ARVCF BAHCC1

1.46e-0416613454586d6725403f879fc96f67be579022587ce1906
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NIBAN1 PPM1E GPC6 ADAMTS12 GUCY1A1

1.51e-041671345784776d1fcc098f84d3c2eca58fa56cb9428f434
Diseasecolorectal adenocarcinoma (biomarker_via_orthology)

TYMS BRD8

2.02e-0521332DOID:0050861 (biomarker_via_orthology)
DiseaseColorectal Neoplasms

TCERG1L SYNE1 PPM1E ABCB4 TXNRD1 TYMS FEN1

2.71e-042771337C0009404
Diseasecoronary artery disease

HJV COL4A2 LAYN BCAS3 ARHGAP26 DOCK9 RSBN1 OIT3 R3HCC1L ARVCF GUCY1A1 EXOC3L2 FBXL20 MCTP2 TBCD

3.27e-04119413315EFO_0001645
Diseaseseptic shock

COL4A2 ARHGAP26

4.17e-0471332EFO_0006834
Diseaselimb-girdle muscular dystrophy (implicated_via_orthology)

MYOF FER1L4

4.17e-0471332DOID:11724 (implicated_via_orthology)
Disease2-hydroxyglutaric acid measurement

ARHGEF18 ADAMTS15

7.11e-0491332EFO_0010446
Diseasesevere acute respiratory syndrome, COVID-19

COL4A2 SEMA4B ARHGEF18 GRM7 ADAMTS12 TMEM132C PCDH11X CRNN

9.82e-044471338EFO_0000694, MONDO_0100096
DiseaseNeuroendocrine Tumors

SSTR2 TYMS

1.08e-03111332C0206754
DiseaseColorectal Carcinoma

TCERG1L SYNE1 PPM1E ABCB4 TXNRD1 TYMS FEN1 PCDH11X ADAMTS15 ATP11C

1.34e-0370213310C0009402
Diseaseessential hypertension, age at diagnosis

GUCY1A1 MTMR9 BAHCC1

2.08e-03561333EFO_0004918, MONDO_0001134
Diseasearterial stiffness measurement

COL4A2 GPC6 SEC14L5

3.05e-03641333EFO_0004517
Diseaseresponse to mitochondrial complex I inhibitor

TXNRD1 GLCE

3.28e-03191332EFO_0600033
Diseaseglomerulonephritis (is_marker_for)

BDKRB1 CD163

3.28e-03191332DOID:2921 (is_marker_for)
Diseaseinterstitial lung disease

MUC5B THSD7B CRABP1

3.47e-03671333EFO_0004244
Diseasebipolar I disorder

SYNE1 EEF1A2 STARD9 ATP2A2

3.87e-031411334EFO_0009963
DiseaseImmunosuppressant use measurement

TMEM151B RSBN1

4.00e-03211332EFO_0009934
Diseaseblood pressure

SYNE1 GPC6

4.39e-03221332EFO_0004325

Protein segments in the cluster

PeptideGeneStartEntry
EREGSRIIAQKRACD

CALCA

71

P06881
VDEERRTGLQCETGK

FAM228A

71

Q86W67
GTLRGLEDECVTDVK

EXOC3L2

16

Q2M3D2
TREEVSRTRCGGRKD

BDKRB1

231

P46663
KAIVRGEETLRVGDC

BAHCC1

2506

Q9P281
GVCRDDVDRGKNNVT

BTNL3

356

Q6UXE8
SECEKGQRLREIAGK

ARHGEF18

646

Q6ZSZ5
GKLITIGQERFRCSE

ACTL7B

286

Q9Y614
RDTDNKAAIRDCGGV

ARVCF

431

O00192
QEVGRSCIILEFKGR

CPSF3

21

Q9UKF6
GREIKASEGERELCR

BRD8

981

Q9H0E9
QREDKACSRIVGALE

ADGRA2

506

Q96PE1
KCRVVDRQEEGNGDS

ADGRB1

1196

O14514
LKRCGNGVVEREEQC

ADAM21

406

Q9UKJ8
KETTIQGLDGLSERC

ALDOB

121

P05062
CDTDVKRAVGGDRQE

COL4A2

661

P08572
GVSRVQEECRTAKGD

BRWD3

741

Q6RI45
NVEVRDRVKCISGVE

GLCE

181

O94923
NQSGEGCVITRDRKE

ASAH1

286

Q13510
EAKGQEKTCRETEVG

DUS3L

46

Q96G46
RGVEETAAECRKLGV

HSD17B13

71

Q7Z5P4
EIEQELTSKQGGRCS

BCAS3

466

Q9H6U6
GECLKEISESRVVSG

BPTF

1546

Q12830
KGKDRTVAEGEECAR

CAVIN4

276

Q5BKX8
NRGTERVRKDLSTGC

CASP8AP2

256

Q9UKL3
RITALCETKDEGGKR

ATG2A

936

Q2TAZ0
SGGFKIREIQCVDSR

ADAMTS12

1381

P58397
KRAVDCRGSAGQRTV

ADAMTS15

861

Q8TE58
RRAKLVACDGNEIDT

ABHD16B

141

Q9H3Z7
LETGLTCKNEDQTGR

MUC5B

1851

Q9HC84
RGAVLLKTGDEEESC

R3HCC1L

26

Q7Z5L2
DVTRQLQEKGCGART

RBMX2

126

Q9Y388
GFEEETVDGRKCRSL

CRABP1

71

P29762
GAITIDTARRLCKEG

HJV

336

Q6ZVN8
NRIGLEEEKLTGDRC

PTPN2

316

P17706
ESLDLGVRCKRGEER

KIRREL3-AS3

6

Q8N7Y1
KSRIEQGIVDRSETG

LRRC8A

216

Q8IWT6
EEIRCKAIERGTGND

NUB1

61

Q9Y5A7
RKCGRGVTDVVITRE

OGFOD3

106

Q6PK18
KEGLRAEACESARLG

KRBA1

541

A5PL33
KEGRNLVVRDRCGTS

MCTP2

201

Q6DN12
LTGTNGRRCKEDEKL

MTMR9

206

Q96QG7
ERTQASAEGCKEGRE

GARIN4

411

Q8IYT1
EAKEACRRDGGQLVS

LAYN

66

Q6UX15
IGTDNVCRDRLEKTI

IPO11

256

Q9UI26
SVVEEERGRDCGKIQ

FER1L4

686

A9Z1Z3
GKREGEELIQAEARC

CYP2S1

141

Q96SQ9
SAGQREGCRKREAEL

MYH7B

1206

A7E2Y1
CECGVGRVLRSDGKT

OIT3

206

Q8WWZ8
GRVLRSDGKTCEDVE

OIT3

211

Q8WWZ8
EVCEEAGVKGTLGRL

NUDT3

66

O95989
SAERAGLCVGDKITE

PDZD7

121

Q9H5P4
CEAENILGKDTVRGR

NRG2

311

O14511
CRGLIKNGERQDEES

INTS2

226

Q9H0H0
ERSEEKGGVEVLESC

METTL16

466

Q86W50
DIALTRGAEVKGRCG

LAMP5

86

Q9UJQ1
GLRSQKSDERQGVCI

GCN1

1971

Q92616
KSDERQGVCIGLSEI

GCN1

1976

Q92616
VVGGREIKDGERCLD

KLHL40

416

Q2TBA0
EEGGVCITEALITKR

LRRC46

11

Q96FV0
LSGTVVELRCQDKEG

JAM2

146

P57087
KGRTEVNQCSIDLGE

GPR101

336

Q96P66
TTGARIDREKLCAGI

PCDH11X

86

Q9BZA7
ERGLTCEGDKTIVGS

CLPS

81

P04118
TEGNCTALTRGELKR

CRNN

21

Q9UBG3
QEALDKAREGRTCIV

ABCB4

1221

P21439
GSRKERCIGQIFQTE

PPP1R3A

986

Q16821
REDEKQRIEALGGCV

PPM1E

371

Q8WY54
QGRSSQELEGSCRKD

ITGB2

486

P05107
ICIREIEARGLKSEG

CHN2

296

P52757
IIDCVGSDGKERRQL

ATM

2701

Q13315
DNKGTAVAICRRIGI

ATP2A2

626

P16615
NRVGERRREKGEATC

CHCHD1

31

Q96BP2
AECTRRIVGVDGAIK

HECTD1

86

Q9ULT8
AGQRDLGTRKTISEC

FAM124B

421

Q9H5Z6
CGEKQFSEERIRSGV

FEN1

311

P39748
AGADVKARSCGEVRQ

GPC6

21

Q9Y625
GRDDLSKRGVDQTCT

DOCK10

2151

Q96BY6
GKRQGGVEEQCKRRT

DOCK9

1906

Q9BZ29
SVKDIRRGNVCGDSK

EEF1A2

316

Q05639
GGTVCREESRNGLEK

CEP85L

171

Q5SZL2
CEAENSKGRDTVQGR

CNTN2

306

Q02246
GVCRDSVERKGEVLL

BTN2A1

401

Q7KYR7
ALDTGDKVVQCGRRV

CSAD

346

Q9Y600
TDRKCTGQERIGKDS

GRM7

386

Q14831
LAKECGVENIRRAES

FECH

356

P22830
LRLVDGENKCSGRVE

CD163

51

Q86VB7
SVNEEGQKRCEGSTR

SEC14L5

356

O43304
EVKGATGECNISERK

KCTD3

696

Q9Y597
ECIAENSRGKNVARG

CNTN3

296

Q9P232
KRGNSDIVRLVIECG

MPHOSPH8

676

Q99549
QSQLRLEEKTRECGT

ODF2

696

Q5BJF6
DCGLTGKRELEVDSQ

RSBN1

721

Q5VWQ0
GVKQEKTEDGRRSAC

TRIM33

791

Q9UPN9
AVGVCRDSVSRKGEL

TRIM39

406

Q9HCM9
VGKSENDLEGRIVCV

PLCB4

86

Q15147
AVEEIRNGVTKRGET

SYNE1

1166

Q8NF91
RETREVRGSCRLKGD

TMEM132C

176

Q8N3T6
RCGVRDVSKTLVGLE

TMEM151B

211

Q8IW70
DIEGRVVENISKRCG

FBXL20

76

Q96IG2
GGEDESVILKSCTRR

ARHGAP26

311

Q9UNA1
NTIVSRIARICKGDE

SEMA4B

276

Q9NPR2
RIARICKGDEGGERV

SEMA4B

281

Q9NPR2
CGETQKRIGTADREL

SH3GLB1

121

Q9Y371
VDLNTREVIRESGKC

STARD9

1821

Q9P2P6
GTDVVIVKNGRRICG

SPRYD7

36

Q5W111
VLCLVKVSGTDDGER

SSTR2

326

P30874
DTCKILIETRGSEQG

CD300LB

56

A8K4G0
SECAGEEKRVGTRTV

ATP11C

11

Q8NB49
EREGVRINDRQCTGI

TECTA

1826

O75443
DQDVKTKRNRTEGCG

TCERG1L

411

Q5VWI1
IGRDACTRKIGLETV

TXNRD1

441

Q16881
EECRALTKGLEGTIR

NIBAN1

296

Q9BZQ8
EKDGILTVSCENRGI

SLITRK5

56

O94991
GLDGKVICGSRVRVE

SRSF7

66

Q16629
LRCGVRKDDRTGTGT

TYMS

41

P04818
RECRVVLVEGKARGC

UBR1

1671

Q8IWV7
DISILATGCKGREET

TP53BP1

596

Q12888
LDVAKTLGDQTGECR

TTC28

261

Q96AY4
GESQDICKSAGRVKR

ZNF165

221

P49910
GRECIKGVNTERSSK

ZNF528

81

Q3MIS6
EAGKLVDRSVENCVR

TLN2

741

Q9Y4G6
DEKRGACSVGTNVRD

TBCD

451

Q9BTW9
GRLCTECGLQVEERK

WNT8A

291

Q9H1J5
GRVLVEGGSDEKRLC

TOGARAM1

141

Q9Y4F4
QERGEAERTCEGRRK

TMC2

86

Q8TDI7
QSRKIRCVNTADGEG

THSD7B

1086

Q9C0I4
ERVKGGERQASVCRD

TIGD5

66

Q53EQ6
IAECETRLGKQGRRV

SIRT5

121

Q9NXA8
QATGLDEEKRARCDG

TCHH

91

Q07283
SEGRKERTAECALRG

nan

31

Q96M66
CDLGKQERSREVVGT

THSD8

66

A0A1W2PP97
EDDGCLLKQESRGRR

nan

181

Q8N7P7
QRCEECGKGIRATSD

ZNF7

196

P17097
KGIDQKGEERSSCIS

TRIM16L

231

Q309B1
CQEAGKRGRLEDASI

GUCY1A1

176

Q02108
CRDDGIDVRLRGVKI

HECTD3

356

Q5T447
VECGGERVESVVIKN

MYOF

1331

Q9NZM1
QAKTEVETREIGVGC

MYZAP

416

P0CAP1