Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	RNA helicase activity	DDX12P DDX23 DDX43 DDX39A DDX24 DDX39B	3.27e-06	78	104	6	GO:0003724
GeneOntologyMolecularFunction	ATP-dependent activity	DDX12P MYO7B MYO9B TOP6BL DNAH1 CCT6A DNAH17 SMARCA1 DDX23 MACF1 DDX43 DDX39A DDX24 DDX39B	3.63e-06	614	104	14	GO:0140657
GeneOntologyMolecularFunction	ATP-dependent activity, acting on RNA	DDX12P DDX23 DDX43 DDX39A DDX24 DDX39B	3.80e-06	80	104	6	GO:0008186
GeneOntologyMolecularFunction	catalytic activity, acting on RNA	DDX12P POLR3C SARS1 DDX23 PARN DDX43 QTRT1 DDX39A DDX24 DDX39B SMG6	1.13e-05	417	104	11	GO:0140098
GeneOntologyMolecularFunction	helicase activity	DDX12P SMARCA1 DDX23 DDX43 DDX39A DDX24 DDX39B	1.90e-05	158	104	7	GO:0004386
GeneOntologyMolecularFunction	catalytic activity, acting on a nucleic acid	DDX12P TOP6BL POLR3C SARS1 SMARCA1 DDX23 PARN DDX43 QTRT1 DDX39A DDX24 DDX39B SMG6	3.04e-05	645	104	13	GO:0140640
GeneOntologyMolecularFunction	ATP hydrolysis activity	DDX12P MYO9B CCT6A DDX23 MACF1 DDX43 DDX39A DDX24 DDX39B	4.97e-04	441	104	9	GO:0016887
GeneOntologyMolecularFunction	lysine-acetylated histone binding	BRD3 BRD4 TAF1	5.03e-04	30	104	3	GO:0070577
GeneOntologyMolecularFunction	acetylation-dependent protein binding	BRD3 BRD4 TAF1	5.55e-04	31	104	3	GO:0140033
Domain	Q_MOTIF	DDX23 DDX43 DDX39A DDX24 DDX39B	1.67e-06	37	102	5	PS51195
Domain	RNA_helicase_DEAD_Q_motif	DDX23 DDX43 DDX39A DDX24 DDX39B	1.67e-06	37	102	5	IPR014014
Domain	Helicase_C	SMARCA1 DDX23 DDX43 DDX39A DDX24 DDX39B	2.65e-05	107	102	6	PF00271
Domain	HELICc	SMARCA1 DDX23 DDX43 DDX39A DDX24 DDX39B	2.65e-05	107	102	6	SM00490
Domain	Helicase_C	SMARCA1 DDX23 DDX43 DDX39A DDX24 DDX39B	2.79e-05	108	102	6	IPR001650
Domain	HELICASE_CTER	SMARCA1 DDX23 DDX43 DDX39A DDX24 DDX39B	2.94e-05	109	102	6	PS51194
Domain	HELICASE_ATP_BIND_1	SMARCA1 DDX23 DDX43 DDX39A DDX24 DDX39B	2.94e-05	109	102	6	PS51192
Domain	DEXDc	SMARCA1 DDX23 DDX43 DDX39A DDX24 DDX39B	2.94e-05	109	102	6	SM00487
Domain	Helicase_ATP-bd	SMARCA1 DDX23 DDX43 DDX39A DDX24 DDX39B	3.10e-05	110	102	6	IPR014001
Domain	DEAD/DEAH_box_helicase_dom	DDX23 DDX43 DDX39A DDX24 DDX39B	4.92e-05	73	102	5	IPR011545
Domain	DEAD	DDX23 DDX43 DDX39A DDX24 DDX39B	4.92e-05	73	102	5	PF00270
Domain	BET	BRD3 BRD4	1.76e-04	4	102	2	PF17035
Domain	NET_dom	BRD3 BRD4	1.76e-04	4	102	2	IPR027353
Domain	NET	BRD3 BRD4	1.76e-04	4	102	2	PS51525
Domain	Bromodomain_CS	BRD3 BRD4 TAF1	3.75e-04	26	102	3	IPR018359
Domain	DEAD_ATP_HELICASE	DDX23 DDX43 DDX24	6.36e-04	31	102	3	PS00039
Domain	RNA-helicase_DEAD-box_CS	DDX23 DDX43 DDX24	7.66e-04	33	102	3	IPR000629
Domain	BROMODOMAIN_1	BRD3 BRD4 TAF1	1.07e-03	37	102	3	PS00633
Domain	Bromodomain	BRD3 BRD4 TAF1	1.16e-03	38	102	3	PF00439
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	CUL3 MCMBP PSMB7 LARP1 CCT6A MLF2 UBE2O SARS1 BYSL TOLLIP HTATSF1 MACF1 APPL1 SCPEP1 STIP1 DDX39A RPA2 NUDC HECTD1 DDX39B	1.25e-08	1455	105	20	22863883
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	BRD3 NUP214 GPRIN1 DYSF MAP3K4 SARS1 DDX23 DDX24 ARMH3 NUDC RSBN1L KDM4B	3.73e-08	497	105	12	36774506
Pubmed	ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure.	LEMD3 LARP1 CWC22 S100A9 CCT6A SMARCA1 ZNF638 MACF1 STIP1 NUDC	4.35e-08	315	105	10	26777405
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	CHERP LEMD3 ICE2 LARP1 SLC6A15 GPRC5C NUP214 ADCY9 UBE2O ZNF638 SCPEP1 SEC63 HECTD1 RSBN1L	4.73e-08	733	105	14	34672954
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	CUL3 CHERP NUP214 CCT6A BYSL ZNF638 DDX23 HTATSF1 ZSCAN2 SEC63 DDX39A DDX24 NUDC GOLGB1	6.69e-08	754	105	14	35906200
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	RELN CHERP BRD3 CWC22 MYEF2 S100A9 CCT6A BRD4 ZNF638 DDX23 MACF1 SEC63 DDX39A DDX24 DDX39B AFF4	1.61e-07	1082	105	16	38697112
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	CHERP LEMD3 LARP1 NUP214 CWC22 BRD4 BYSL ZNF638 HTATSF1 PARN TAF1 DDX24 DDX39B RSBN1L AFF4	1.88e-07	954	105	15	36373674
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	CRYBG2 BRD3 NUP214 CCT6A MLF2 BRD4 SMARCA1 ZNF638 HTATSF1 NUDC UNC79	1.90e-07	469	105	11	27634302
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	MCMBP LARP1 S100A9 CCT6A SERPINB6 UBE2O SARS1 BYSL ZNF638 DDX23 HTATSF1 MACF1 STIP1 DDX24 NUDC HECTD1 DDX39B GOLGB1	2.33e-07	1415	105	18	28515276
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	MCMBP CHERP LARP1 NUP214 CWC22 S100A9 CCT6A UBE2O SARS1 BYSL SMARCA1 SCPEP1 STIP1 SEC63 DDX24 RPA2 NUDC DDX39B	2.59e-07	1425	105	18	30948266
Pubmed	BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.	CHERP LARP1 NUP214 CWC22 CCT6A MLF2 HPF1 DDX23 STIP1 DDX43 SEC63 DDX39A DDX24 RPA2 NUDC DDX39B RSBN1L	4.35e-07	1318	105	17	30463901
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	SLC9A8 GNPTAB ADGRV1 ADCY9 MACF1 APPL1 KDM4B SMG6	4.41e-07	225	105	8	12168954
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	MCMBP LEMD3 SLC6A15 GPRIN1 ADCY9 TBC1D8 MLF2 UBE2O SARS1 BYSL DDX23 HTATSF1 MACF1 STIP1 SEC63 DDX24 NUDC GOLGB1	4.81e-07	1487	105	18	33957083
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	USP53 CUL3 LARP1 ADGRV1 CWC22 ADCY9 MYEF2 LRIG3 UBE2O KDM4B SMG6	6.25e-07	529	105	11	14621295
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	CHERP LARP1 NUP214 MYEF2 UBE2O BYSL ZNF638 DDX23 MACF1 PARN DDX24 HECTD1	6.91e-07	653	105	12	22586326
Pubmed	Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.	NUP214 CCT6A SERPINB6 SARS1 ZNF638 STIP1 TAF1 DDX39A DDX39B	7.95e-07	332	105	9	32786267
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	MCMBP MYO9B LARP1 NUP214 DNAH1 CCT6A SARS1 TOLLIP STIP1 DDX39A DDX24 RPA2 NUDC HECTD1 DDX39B AFF4	1.06e-06	1247	105	16	27684187
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	DOCK2 CHERP CCT6A BRD4 ZNF638 DDX23 MACF1 DDX39A NUDC DDX39B GOLGB1	1.58e-06	582	105	11	20467437
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	ICE2 LARP1 NUP214 GPRIN1 ADCY9 TBC1D8 CCT6A MACF1 STIP1 SEC63 NUDC GOLGB1	1.60e-06	708	105	12	39231216
Pubmed	MYC multimers shield stalled replication forks from RNA polymerase.	MCMBP CHERP CWC22 S100A9 CCT6A BYSL ZNF638 DDX23 PARN SEC63 DDX24 DDX39B RSBN1L AFF4	1.72e-06	989	105	14	36424410
Pubmed	Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins.	LARP1 CWC22 SARS1 BRD4 BYSL DDX23 HTATSF1 STIP1 SEC63 DDX39A RPA2 KDM4B	1.99e-06	723	105	12	34133714
Pubmed	POH1 contributes to hyperactivation of TGF-β signaling and facilitates hepatocellular carcinoma metastasis through deubiquitinating TGF-β receptors and caveolin-1.	ICE2 LRIG3 CCT6A MLF2 DDX39A DDX24 DDX39B RSBN1L	2.09e-06	277	105	8	30745168
Pubmed	CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.	CHERP LARP1 S100A9 BYSL SMARCA1 ZNF638 DDX23 HTATSF1 DDX39A DDX24 DDX39B	2.29e-06	605	105	11	28977666
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	SERPINA3 NRAP LAMA2 DYSF CCT6A MLF2 MACF1 APPL1 STIP1 TAF1	2.79e-06	497	105	10	23414517
Pubmed	Spatiotemporal-resolved protein networks profiling with photoactivation dependent proximity labeling.	CHERP LARP1 BRD4 HTATSF1 APPL1 STIP1 RPA2 NUDC DDX39B	3.58e-06	399	105	9	35987950
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	CHERP NUP214 CCT6A MLF2 UBE2O SARS1 APPL1 STIP1 NUDC HECTD1 DDX39B	3.81e-06	638	105	11	33239621
Pubmed	Prostate cancer-associated SPOP mutations confer resistance to BET inhibitors through stabilization of BRD4.	CUL3 BRD3 BRD4	4.33e-06	11	105	3	28805820
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	CHERP LARP1 NUP214 GPRIN1 UBE2O ZNF638 HTATSF1 MACF1 STIP1 NUDC RSBN1L GOLGB1 AFF4	4.98e-06	934	105	13	33916271
Pubmed	Optimized fragmentation schemes and data analysis strategies for proteome-wide cross-link identification.	LEMD3 PSMB7 CCT6A UBE2O SARS1 BYSL MACF1 STIP1 NUDC DDX39B	5.60e-06	538	105	10	28524877
Pubmed	Elucidation of the BMI1 interactome identifies novel regulatory roles in glioblastoma.	LARP1 POLR3C CCT6A MLF2 NFE2L2 SMARCA1 DDX23 RPA2	7.41e-06	329	105	8	34316702
Pubmed	Targeted ubiquitination and degradation of G-protein-coupled receptor kinase 5 by the DDB1-CUL4 ubiquitin ligase complex.	MYO9B LARP1 CWC22 UBE2O SMARCA1 AFF4	8.25e-06	156	105	6	22952844
Pubmed	Nuclear localization of poly(A)+ mRNA following siRNA reduction of expression of the mammalian RNA helicases UAP56 and URH49.	DDX39A DDX39B	9.03e-06	2	105	2	16949217
Pubmed	Chlorambucil-induced mutations in mice recovered in homozygotes.	RELN BICC1	9.03e-06	2	105	2	1557392
Pubmed	Terminal regions of UAP56 and URH49 are required for their distinct complex formation functioning to an essential role in mRNA processing and export.	DDX39A DDX39B	9.03e-06	2	105	2	38377942
Pubmed	Genetic silencing of Nrf2 enhances X-ROS in dysferlin-deficient muscle.	DYSF NFE2L2	9.03e-06	2	105	2	24600403
Pubmed	Binding of the human cytomegalovirus (HCMV) tegument protein UL69 to UAP56/URH49 is not required for efficient replication of HCMV.	DDX39A DDX39B	9.03e-06	2	105	2	20610707
Pubmed	Structural differences between the closely related RNA helicases, UAP56 and URH49, fashion distinct functional apo-complexes.	DDX39A DDX39B	9.03e-06	2	105	2	38225262
Pubmed	BRD3 and BRD4 BET Bromodomain Proteins Differentially Regulate Skeletal Myogenesis.	BRD3 BRD4	9.03e-06	2	105	2	28733670
Pubmed	The closely related RNA helicases, UAP56 and URH49, preferentially form distinct mRNA export machineries and coordinately regulate mitotic progression.	DDX39A DDX39B	9.03e-06	2	105	2	20573985
Pubmed	Recruitment of Brd3 and Brd4 to acetylated chromatin is essential for proinflammatory cytokine-induced matrix-degrading enzyme expression.	BRD3 BRD4	9.03e-06	2	105	2	30786900
Pubmed	BRD3/4 inhibition and FLT3-ligand deprivation target pathways that are essential for the survival of human MLL-AF9+ leukemic cells.	BRD3 BRD4	9.03e-06	2	105	2	29240787
Pubmed	Parsing the roles of DExD-box proteins DDX39A and DDX39B in alternative RNA splicing.	DDX39A DDX39B	9.03e-06	2	105	2	38801080
Pubmed	Cullin3 aggravates the inflammatory response of periodontal ligament stem cells via regulation of SHH signaling and Nrf2.	CUL3 NFE2L2	9.03e-06	2	105	2	34193016
Pubmed	RAB-like 2 has an essential role in male fertility, sperm intra-flagellar transport, and tail assembly.	CUL3 SERPINA3 CCT6A STIP1 NUDC	9.10e-06	92	105	5	23055941
Pubmed	Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.	LEMD3 PSMB7 NUP214 MYEF2 ZNF638 PARN SEC63 BICC1 GOLGB1	1.06e-05	457	105	9	32344865
Pubmed	Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.	CUL3 MCMBP ICE2 PSMB7 LARP1 CCT6A UBE2O BYSL SMARCA1 ZNF638 STIP1 DDX24 NUDC HECTD1 DDX39B	1.17e-05	1335	105	15	29229926
Pubmed	Human Antiviral Protein IFIX Suppresses Viral Gene Expression during Herpes Simplex Virus 1 (HSV-1) Infection and Is Counteracted by Virus-induced Proteasomal Degradation.	CUL3 CHERP PSMB7 LARP1 MYEF2 BYSL HTATSF1	1.17e-05	251	105	7	28077445
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	CHERP MYO9B NUP214 MYEF2 CCT6A MLF2 ZNF638 DDX23 MACF1 STIP1 NUDC DDX39B GOLGB1	1.33e-05	1024	105	13	24711643
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	MYO9B NUP214 MYEF2 S100A9 CCT6A SERPINB6 BYSL SMARCA1 ZNF638 DDX23 MACF1 DDX43 DDX39A DDX24 DDX39B	1.37e-05	1353	105	15	29467282
Pubmed	NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency.	BRD3 CWC22 BRD4 SMARCA1 DDX24	1.58e-05	103	105	5	32744500
Pubmed	Werner helicase-interacting protein 1 binds polyubiquitin via its zinc finger domain.	CUL3 CCT6A UBE2O HECTD1	1.62e-05	50	105	4	17550899
Pubmed	Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.	LEMD3 SLC6A15 ADCY9 MYEF2 TBC1D8 LRIG3 MLF2 NFE2L2 MACF1 STIP1 DDX39B BICC1 GOLGB1	1.92e-05	1061	105	13	33845483
Pubmed	Blocking an N-terminal acetylation-dependent protein interaction inhibits an E3 ligase.	CUL3 PSMB7 ADGRV1 CCT6A HTATSF1 STIP1 RPA2 NUDC DDX39B	2.00e-05	495	105	9	28581483
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	CUL3 LARP1 BRD3 NUP214 GPRIN1 NOL4L BRD4 ZNF638 APPL1 DDX24 KDM4B	2.31e-05	774	105	11	15302935
Pubmed	The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.	LARP1 NUP214 MYEF2 MLF2 MACF1 DDX39A SMG6	2.47e-05	282	105	7	23667531
Pubmed	Lost in transcription: molecular mechanisms that control HIV latency.	BRD4 TAF1 AFF4	2.50e-05	19	105	3	23518577
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	CUL3 LARP1 CWC22 S100A9 CCT6A MLF2 BYSL SMARCA1 ZNF638 SEC63 DDX24 NUDC DDX39B RSBN1L	2.58e-05	1257	105	14	36526897
Pubmed	Spatial proteomics reveal that the protein phosphatase PTP1B interacts with and may modify tyrosine phosphorylation of the rhomboid protease RHBDL4.	LEMD3 LARP1 NUP214 GPRIN1 SEC63 GOLGB1	2.60e-05	191	105	6	31177093
Pubmed	Electrophilic nitro-fatty acids activate NRF2 by a KEAP1 cysteine 151-independent mechanism.	CUL3 NFE2L2	2.70e-05	3	105	2	21357422
Pubmed	Cul3-mediated Nrf2 ubiquitination and antioxidant response element (ARE) activation are dependent on the partial molar volume at position 151 of Keap1.	CUL3 NFE2L2	2.70e-05	3	105	2	19489739
Pubmed	Heteroaromatic 4-arylquinols are novel inducers of nuclear factor-erythroid 2-related factor 2 (Nrf2).	CUL3 NFE2L2	2.70e-05	3	105	2	20599909
Pubmed	CUL3 and NRF2 mutations confer an NRF2 activation phenotype in a sporadic form of papillary renal cell carcinoma.	CUL3 NFE2L2	2.70e-05	3	105	2	23365135
Pubmed	Development of a High-Throughput Cul3-Keap1 Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) Assay for Identifying Nrf2 Activators.	CUL3 NFE2L2	2.70e-05	3	105	2	30383469
Pubmed	The Keap1-BTB protein is an adaptor that bridges Nrf2 to a Cul3-based E3 ligase: oxidative stress sensing by a Cul3-Keap1 ligase.	CUL3 NFE2L2	2.70e-05	3	105	2	15367669
Pubmed	Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2.	CUL3 NFE2L2	2.70e-05	3	105	2	15282312
Pubmed	Zinc-binding triggers a conformational-switch in the cullin-3 substrate adaptor protein KEAP1 that controls transcription factor NRF2.	CUL3 NFE2L2	2.70e-05	3	105	2	30261176
Pubmed	Covalent modification of Keap1 at Cys77 and Cys434 by pubescenoside a suppresses oxidative stress-induced NLRP3 inflammasome activation in myocardial ischemia-reperfusion injury.	CUL3 NFE2L2	2.70e-05	3	105	2	33391509
Pubmed	Diffusion dynamics of the Keap1-Cullin3 interaction in single live cells.	CUL3 NFE2L2	2.70e-05	3	105	2	23454126
Pubmed	Gene-expression signature regulated by the KEAP1-NRF2-CUL3 axis is associated with a poor prognosis in head and neck squamous cell cancer.	CUL3 NFE2L2	2.70e-05	3	105	2	29306329
Pubmed	An integrative investigation on significant mutations and their down-stream pathways in lung squamous cell carcinoma reveals CUL3/KEAP1/NRF2 relevant subtypes.	CUL3 NFE2L2	2.70e-05	3	105	2	32434476
Pubmed	Integrated analysis of patients with KEAP1/NFE2L2/CUL3 mutations in lung adenocarcinomas.	CUL3 NFE2L2	2.70e-05	3	105	2	34617407
Pubmed	Induction of activation of the antioxidant response element and stabilization of Nrf2 by 3-(3-pyridylmethylidene)-2-indolinone (PMID) confers protection against oxidative stress-induced cell death.	CUL3 NFE2L2	2.70e-05	3	105	2	22245129
Pubmed	The RNA helicase DDX39B and its paralog DDX39A regulate androgen receptor splice variant AR-V7 generation.	DDX39A DDX39B	2.70e-05	3	105	2	28025139
Pubmed	Growth-regulated expression and G0-specific turnover of the mRNA that encodes URH49, a mammalian DExH/D box protein that is highly related to the mRNA export protein UAP56.	DDX39A DDX39B	2.70e-05	3	105	2	15047853
Pubmed	Comparative structure-function analysis of bromodomain and extraterminal motif (BET) proteins in a gene-complementation system.	BRD3 BRD4	2.70e-05	3	105	2	31792058
Pubmed	Carnosic acid prevents dextran sulfate sodium-induced acute colitis associated with the regulation of the Keap1/Nrf2 pathway.	CUL3 NFE2L2	2.70e-05	3	105	2	28887507
Pubmed	Hcc-1 is a novel component of the nuclear matrix with growth inhibitory function.	DDX39A DDX39B	2.70e-05	3	105	2	15338056
Pubmed	BRD-NUT oncoproteins: a family of closely related nuclear proteins that block epithelial differentiation and maintain the growth of carcinoma cells.	BRD3 BRD4	2.70e-05	3	105	2	17934517
Pubmed	Hippuric Acid Promotes Renal Fibrosis by Disrupting Redox Homeostasis via Facilitation of NRF2-KEAP1-CUL3 Interactions in Chronic Kidney Disease.	CUL3 NFE2L2	2.70e-05	3	105	2	32854194
Pubmed	Bromodomain and Extraterminal (BET) Protein Inhibition Restores Redox Balance and Inhibits Myofibroblast Activation.	BRD3 BRD4	2.70e-05	3	105	2	31119153
Pubmed	An autoregulatory loop between Nrf2 and Cul3-Rbx1 controls their cellular abundance.	CUL3 NFE2L2	2.70e-05	3	105	2	20452971
Pubmed	Bromo- and extraterminal domain chromatin regulators serve as cofactors for murine leukemia virus integration.	BRD3 BRD4	2.70e-05	3	105	2	24049186
Pubmed	Absolute Amounts and Status of the Nrf2-Keap1-Cul3 Complex within Cells.	CUL3 NFE2L2	2.70e-05	3	105	2	27697860
Pubmed	Activation of Nrf2 by arsenite and monomethylarsonous acid is independent of Keap1-C151: enhanced Keap1-Cul3 interaction.	CUL3 NFE2L2	2.70e-05	3	105	2	18417180
Pubmed	Impact of KEAP1/NFE2L2/CUL3 mutations on duration of response to EGFR tyrosine kinase inhibitors in EGFR mutated non-small cell lung cancer.	CUL3 NFE2L2	2.70e-05	3	105	2	31319993
Pubmed	Cancer related mutations in NRF2 impair its recognition by Keap1-Cul3 E3 ligase and promote malignancy.	CUL3 NFE2L2	2.70e-05	3	105	2	18757741
Pubmed	The bromodomain protein BRD4 regulates the KEAP1/NRF2-dependent oxidative stress response.	NFE2L2 BRD4	2.70e-05	3	105	2	24763052
Pubmed	Dimerization of substrate adaptors can facilitate cullin-mediated ubiquitylation of proteins by a "tethering" mechanism: a two-site interaction model for the Nrf2-Keap1 complex.	CUL3 NFE2L2	2.70e-05	3	105	2	16790436
Pubmed	Involvement of Nrf2 activation in the upregulation of S100A9 by exposure to inorganic arsenite.	S100A9 NFE2L2	2.70e-05	3	105	2	23165982
Pubmed	Britanin Ameliorates Cerebral Ischemia-Reperfusion Injury by Inducing the Nrf2 Protective Pathway.	CUL3 NFE2L2	2.70e-05	3	105	2	28186440
Pubmed	Targeting cullin 3 by miR-601 activates Nrf2 signaling to protect retinal pigment epithelium cells from hydrogen peroxide.	CUL3 NFE2L2	2.70e-05	3	105	2	31178131
Pubmed	Interferon-induced antiviral protein MxA interacts with the cellular RNA helicases UAP56 and URH49.	DDX39A DDX39B	2.70e-05	3	105	2	21859714
Pubmed	The novel BET-CBP/p300 dual inhibitor NEO2734 is active in SPOP mutant and wild-type prostate cancer.	CUL3 BRD4	2.70e-05	3	105	2	31559706
Pubmed	BET Proteins Exhibit Transcriptional and Functional Opposition in the Epithelial-to-Mesenchymal Transition.	BRD3 BRD4	2.70e-05	3	105	2	29437854
Pubmed	WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.	BRD3 BRD4 ZNF638 DDX23 PARN TAF1 DDX24 RPA2	2.71e-05	394	105	8	27248496
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	LEMD3 PSMB7 SLC6A15 GPRC5C NUP214 MLF2 UBE2O SARS1 BYSL TOLLIP SEC63 HECTD1	2.82e-05	942	105	12	31073040
Pubmed	Identification and functional characterization of transcriptional activators in human cells.	LARP1 BRD3 BRD4 EPC1 STIP1 TAF1 RPA2 KDM4B	2.91e-05	398	105	8	35016035
Pubmed	The ubiquitin-dependent ATPase p97 removes cytotoxic trapped PARP1 from chromatin.	CUL3 CHERP BRD3 S100A9 MLF2 BYSL STIP1 HECTD1	3.01e-05	400	105	8	35013556
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	C16orf96 BRD3 ADCY9 MYEF2 LRIG3 BRD4 EPC1 SMARCA1 MACF1 TAF1 DDX24 RSBN1L AFF4	3.25e-05	1116	105	13	31753913
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	ZNF821 RELN GNPTAB UBE2O NFE2L2 HPF1 TOLLIP MACF1 APPL1 TAF1 QTRT1 HECTD1 RSBN1L AFF4	3.28e-05	1285	105	14	35914814
Interaction	THOC2 interactions	CUL3 GNPTAB BRD3 CWC22 TBC1D8 CCT6A UBE2O BRD4 DDX23 STIP1 DDX39A RPA2 HECTD1 DDX39B	7.09e-12	219	104	14	int:THOC2
Interaction	H3C1 interactions	CHERP LEMD3 PSMB7 LAMA2 LARP1 BRD3 GPRIN1 DNAH1 SARS1 NFE2L2 BRD4 HPF1 SMARCA1 ZNF638 FOLH1B PARN TAF1 DDX24 RPA2 RSBN1L AFF4	5.45e-09	901	104	21	int:H3C1
Interaction	CHD4 interactions	CUL3 CHERP LARP1 BRD3 CWC22 S100A9 NOL4L UBE2O BRD4 BYSL SMARCA1 ZNF638 DDX23 HTATSF1 STIP1 DDX39A DDX24 RPA2 HECTD1 DDX39B	5.81e-08	938	104	20	int:CHD4
Interaction	DDX41 interactions	CUL3 BRD3 CWC22 UBE2O BRD4 DDX23 STIP1 RPA2 HECTD1	1.98e-07	166	104	9	int:DDX41
Interaction	G3BP1 interactions	CUL3 MCMBP LEMD3 LARP1 NUP214 CWC22 S100A9 CCT6A BRD4 SMARCA1 ZNF638 TOLLIP MACF1 STIP1 SEC63 RPA2 NUDC HECTD1	2.50e-07	835	104	18	int:G3BP1
Interaction	SMARCA4 interactions	CUL3 BRD3 MYEF2 POLR3C UBE2O NFE2L2 BRD4 BYSL SMARCA1 STIP1 RPA2 HECTD1 KDM4B	7.50e-07	462	104	13	int:SMARCA4
Interaction	TERF2IP interactions	CUL3 POLR3C BRD4 SMARCA1 ZNF638 DDX23 HTATSF1 PARN TAF1 DDX39A DDX24 RPA2 HECTD1 AFF4	9.40e-07	552	104	14	int:TERF2IP
Interaction	U2AF2 interactions	CUL3 CHERP PSMB7 LARP1 BRD3 S100A9 CCT6A UBE2O BRD4 DDX23 STIP1 DDX39A RPA2 HECTD1 DDX39B	1.23e-06	651	104	15	int:U2AF2
Interaction	DDX18 interactions	USP53 CUL3 BRD3 UBE2O BRD4 BYSL DDX23 STIP1 DDX24 RPA2 HECTD1	1.24e-06	334	104	11	int:DDX18
Interaction	SNW1 interactions	DOCK2 CUL3 MCMBP CHERP TEX11 CCT6A SARS1 BRD4 BYSL ZNF638 DDX23 DDX39A RPA2 NUDC HECTD1 DDX39B	1.37e-06	747	104	16	int:SNW1
Interaction	DYNC1H1 interactions	USP53 CUL3 MCMBP PSMB7 LARP1 UBE2O BRD4 TOLLIP HTATSF1 STIP1 RPA2 NUDC DDX39B	1.48e-06	491	104	13	int:DYNC1H1
Interaction	PIP4K2C interactions	CHERP PSMB7 LARP1 BRD3 UBE2O BRD4 DDX23 AFF4	1.71e-06	159	104	8	int:PIP4K2C
Interaction	DHX15 interactions	CUL3 MCMBP CHERP LARP1 DYSF S100A9 CCT6A UBE2O BRD4 STIP1 DDX43 RPA2 DDX39B	1.89e-06	502	104	13	int:DHX15
Interaction	MAT2A interactions	CUL3 LEMD3 CCT6A UBE2O BRD4 HTATSF1 STIP1 RPA2 NUDC	1.94e-06	218	104	9	int:MAT2A
Interaction	RBM17 interactions	CUL3 CHERP UBE2O BRD4 TOLLIP DDX23 RPA2 HECTD1 DDX39B	1.94e-06	218	104	9	int:RBM17
Interaction	SUMO2 interactions	CUL3 BRD3 NUP214 CCT6A SERPINB6 SARS1 NFE2L2 BRD4 ZNF638 PARN STIP1 TAF1 DDX39A DDX39B	2.10e-06	591	104	14	int:SUMO2
Interaction	RBM33 interactions	MYO9B BRD3 BRD4 STIP1 DDX39A RPA2 DDX39B	2.48e-06	117	104	7	int:RBM33
Interaction	DDX46 interactions	USP53 CUL3 CHERP BRD4 DDX23 STIP1 RPA2 NUDC HECTD1	2.71e-06	227	104	9	int:DDX46
Interaction	DHX8 interactions	CUL3 CHERP CWC22 ZNF638 DDX23 HTATSF1 RPA2 HECTD1 RSBN1L AFF4	2.75e-06	292	104	10	int:DHX8
Interaction	WRNIP1 interactions	CUL3 BRD4 TOLLIP STIP1 TAF1 RPA2 KDM4B	2.77e-06	119	104	7	int:WRNIP1
Interaction	TOP1 interactions	CUL3 LARP1 BRD3 MAP3K4 S100A9 UBE2O BRD4 SMARCA1 ZNF638 DDX23 DDX39A DDX24 RPA2 HECTD1 DDX39B	2.81e-06	696	104	15	int:TOP1
Interaction	GNL3 interactions	CUL3 CHERP DYSF UBE2O BRD4 DDX23 STIP1 TAF1 DDX24 RPA2 HECTD1	3.17e-06	368	104	11	int:GNL3
Interaction	PSMD14 interactions	ICE2 PSMB7 LARP1 LRIG3 CCT6A MLF2 BRD4 STIP1 DDX39A DDX24 RPA2 DDX39B RSBN1L	3.22e-06	527	104	13	int:PSMD14
Interaction	CD2BP2 interactions	CUL3 CWC22 POLR3C S100A9 BRD4 DDX23 HTATSF1 RPA2 HECTD1	3.24e-06	232	104	9	int:CD2BP2
Interaction	UBTF interactions	PSMB7 BRD3 UBE2O BRD4 TOLLIP DDX23 TAF1 RPA2 HECTD1	3.47e-06	234	104	9	int:UBTF
Interaction	ACIN1 interactions	USP53 CUL3 BRD3 S100A9 UBE2O BRD4 DDX23 RPA2 HECTD1 DDX39B	3.60e-06	301	104	10	int:ACIN1
Interaction	PNN interactions	BRD3 CWC22 UBE2O BRD4 DDX23 STIP1 HECTD1 DDX39B RSBN1L SMG6	3.71e-06	302	104	10	int:PNN
Interaction	FBXO22 interactions	CUL3 BRD3 NUP214 GPRIN1 DYSF MAP3K4 SARS1 DDX23 DDX24 ARMH3 NUDC RSBN1L KDM4B	4.20e-06	540	104	13	int:FBXO22
Interaction	ZNF300 interactions	CUL3 SLC9A8 DDX39A	4.60e-06	7	104	3	int:ZNF300
Interaction	NOC4L interactions	CUL3 POLR3C BYSL TOLLIP STIP1 DDX39A RPA2 HECTD1	4.86e-06	183	104	8	int:NOC4L
Interaction	HNRNPD interactions	CUL3 LARP1 GPRIN1 DYSF MYEF2 MAP3K4 S100A9 UBE2O NFE2L2 BRD4 STIP1 DDX24 RPA2 HECTD1	5.07e-06	638	104	14	int:HNRNPD
Interaction	RPS7 interactions	CUL3 GNPTAB GPRIN1 UBE2O BRD4 BYSL DDX23 STIP1 DDX24 RPA2 HECTD1 DDX39B	5.12e-06	466	104	12	int:RPS7
Interaction	THOC5 interactions	PSMB7 BRD4 DDX23 DDX39A DDX24 RPA2 DDX39B	5.25e-06	131	104	7	int:THOC5
Interaction	COIL interactions	BRD3 POLR3C BYSL SMARCA1 DDX23 HTATSF1 TAF1 DDX24 RPA2 HECTD1 RSBN1L AFF4 KDM4B	5.32e-06	552	104	13	int:COIL
Interaction	SART1 interactions	CUL3 CHERP BRD3 S100A9 UBE2O BRD4 DDX23 RPA2 HECTD1 DDX39B	5.69e-06	317	104	10	int:SART1
Interaction	RBM39 interactions	CUL3 CHERP LARP1 CWC22 MYEF2 S100A9 CCT6A UBE2O BRD4 BYSL DDX23 STIP1 DDX39A DDX24 RPA2 NUDC HECTD1 DDX39B	5.89e-06	1042	104	18	int:RBM39
Interaction	DIMT1 interactions	CUL3 UBE2O BYSL DDX39A DDX24 RPA2 HECTD1 DDX39B	6.17e-06	189	104	8	int:DIMT1
Interaction	NOLC1 interactions	CUL3 BRD3 UBE2O FAM186A BRD4 DDX23 HTATSF1 RPA2 HECTD1 AFF4	7.08e-06	325	104	10	int:NOLC1
Interaction	PES1 interactions	CUL3 CWC22 UBE2O BRD4 DDX23 STIP1 DDX24 RPA2 AFF4	7.66e-06	258	104	9	int:PES1
Interaction	PCID2 interactions	CUL3 BRD3 TOLLIP RPA2 HECTD1 DDX39B	8.13e-06	92	104	6	int:PCID2
Interaction	GTF2F2 interactions	USP53 BRD3 UBE2O BRD4 DDX23 HTATSF1 RPA2	9.35e-06	143	104	7	int:GTF2F2
Interaction	EIF4A3 interactions	CUL3 CWC22 S100A9 CCT6A UBE2O BRD4 PARN STIP1 RPA2 HECTD1 DDX39B SMG6	1.02e-05	499	104	12	int:EIF4A3
Interaction	RPL31 interactions	CUL3 CHERP LARP1 BRD3 UBE2O BRD4 MACF1 PARN STIP1 TAF1 DDX24 RPA2 HECTD1 RSBN1L	1.04e-05	680	104	14	int:RPL31
Interaction	USP7 interactions	CUL3 ANKRD31 MCMBP MYO7B C16orf96 CWC22 MLF2 UBE2O SLCO1C1 FAM186A BRD4 SMARCA1 ZNF638 MACF1 STIP1 TAF1 DDX24 RPA2 GOLGB1 AFF4	1.09e-05	1313	104	20	int:USP7
Interaction	FTSJ3 interactions	USP53 CUL3 BRD3 UBE2O BRD4 BYSL DDX23 TAF1 DDX24 RPA2 HECTD1	1.16e-05	422	104	11	int:FTSJ3
Interaction	CAP1 interactions	CUL3 LARP1 BRD3 UBE2O SCPEP1 STIP1 RPA2 NUDC	1.20e-05	207	104	8	int:CAP1
Interaction	LIG3 interactions	BRD3 CCT6A BRD4 DDX23 STIP1 RPA2 NUDC HECTD1	1.20e-05	207	104	8	int:LIG3
Interaction	SMC5 interactions	CHERP LEMD3 LARP1 NUP214 CWC22 BRD4 BYSL ZNF638 HTATSF1 PARN TAF1 DDX24 RPA2 HECTD1 DDX39B RSBN1L AFF4	1.36e-05	1000	104	17	int:SMC5
Interaction	NIFK interactions	CUL3 LARP1 BRD3 UBE2O BRD4 DDX23 PARN DDX24 RPA2 HECTD1 AFF4	1.41e-05	431	104	11	int:NIFK
Interaction	ABCA12 interactions	BRD3 BRD4 RPA2	1.56e-05	10	104	3	int:ABCA12
Interaction	SPDYE4 interactions	BRD3 BRD4 STIP1 TAF1 KDM4B	1.57e-05	61	104	5	int:SPDYE4
Interaction	RPSA interactions	CUL3 CHERP LAMA2 LARP1 CCT6A UBE2O BRD4 BYSL STIP1 DDX24 RPA2 HECTD1	1.60e-05	522	104	12	int:RPSA
Interaction	PIP4K2A interactions	LARP1 BRD3 CWC22 UBE2O BRD4 DDX23 RPA2 AFF4	1.63e-05	216	104	8	int:PIP4K2A
Interaction	SNRPC interactions	CUL3 LARP1 CWC22 BRD4 ZNF638 DDX23 HTATSF1 MACF1 DDX39A RPA2 DDX39B	1.71e-05	440	104	11	int:SNRPC
Interaction	SUPT16H interactions	CUL3 BRD3 S100A9 CCT6A UBE2O BRD4 DDX23 STIP1 RPA2 HECTD1 DDX39B	1.78e-05	442	104	11	int:SUPT16H
Interaction	ZNF330 interactions	CUL3 LEMD3 BRD3 UBE2O BYSL SMARCA1 PARN TAF1 DDX24 RSBN1L AFF4	1.94e-05	446	104	11	int:ZNF330
Interaction	RTRAF interactions	CUL3 UBE2O BRD4 BYSL TOLLIP STIP1 RPA2 HECTD1	1.99e-05	222	104	8	int:RTRAF
Interaction	EXOSC10 interactions	USP53 CUL3 BRD4 PARN STIP1 DDX24 RPA2 HECTD1	2.05e-05	223	104	8	int:EXOSC10
Interaction	RPA4 interactions	SERPINA3 MCMBP CHERP LARP1 NUP214 CCT6A ZNF638 STIP1 SEC63 RPA2 NUDC	2.19e-05	452	104	11	int:RPA4
Interaction	LYAR interactions	CUL3 BRD3 MYEF2 BRD4 DDX23 DDX24 RPA2 HECTD1 RSBN1L AFF4	2.33e-05	373	104	10	int:LYAR
Interaction	SNRNP40 interactions	CHERP CWC22 POLR3C CCT6A BRD4 SMARCA1 DDX23 HTATSF1 STIP1 DDX24 RPA2 HECTD1 RSBN1L	2.43e-05	637	104	13	int:SNRNP40
Interaction	UTP14A interactions	BRD3 S100A9 BRD4 BYSL DDX23 PARN RPA2 HECTD1	2.56e-05	230	104	8	int:UTP14A
Interaction	EMG1 interactions	ICE2 PSMB7 BRD3 BRD4 BYSL RPA2	2.64e-05	113	104	6	int:EMG1
Interaction	CCT8 interactions	CUL3 MCMBP CCT6A BRD4 BYSL MACF1 STIP1 RPA2 NUDC HECTD1 DDX39B KDM4B	2.67e-05	550	104	12	int:CCT8
Interaction	SUZ12 interactions	LARP1 NUP214 CCT6A MLF2 UBE2O BRD4 SMARCA1 ZNF638 DDX23 HTATSF1 NUDC HECTD1 DDX39B	2.72e-05	644	104	13	int:SUZ12
Interaction	GPATCH4 interactions	USP53 CUL3 MYEF2 BRD4 DDX23 DDX24 RPA2 HECTD1	2.72e-05	232	104	8	int:GPATCH4
Interaction	POLE4 interactions	BRD4 SEC63 QTRT1 DDX39A	2.75e-05	34	104	4	int:POLE4
Interaction	DHX38 interactions	CUL3 BRD3 BRD4 DDX23 MACF1 RPA2 DDX39B	2.87e-05	170	104	7	int:DHX38
Interaction	SAP18 interactions	GNPTAB BRD3 S100A9 UBE2O BRD4 DDX23 TAF1 DDX39B SMG6	2.89e-05	305	104	9	int:SAP18
Interaction	PWP2 interactions	CUL3 BRD3 BRD4 BYSL STIP1 RPA2 HECTD1	3.09e-05	172	104	7	int:PWP2
Interaction	NOP58 interactions	CUL3 BRD3 UBE2O BRD4 DDX23 STIP1 DDX24 RPA2 HECTD1	3.20e-05	309	104	9	int:NOP58
Interaction	CDC5L interactions	CUL3 CHERP CWC22 CCT6A BRD4 ZNF638 DDX23 MACF1 STIP1 DDX39A RPA2 NUDC HECTD1 DDX39B GOLGB1	3.23e-05	855	104	15	int:CDC5L
Interaction	TCP1 interactions	USP53 CUL3 ACTRT2 CCT6A BRD4 BYSL FOLH1B STIP1 RPA2 DDX39B NPAS4 KDM4B	3.24e-05	561	104	12	int:TCP1
Interaction	RPS2 interactions	CUL3 CHERP LARP1 UBE2O BRD4 BYSL SMARCA1 STIP1 DDX24 RPA2 HECTD1 DDX39B RSBN1L	3.35e-05	657	104	13	int:RPS2
Interaction	AP3D1 interactions	USP53 AP3B2 HTATSF1 STIP1 RPA2 NUDC HECTD1	3.58e-05	176	104	7	int:AP3D1
Interaction	ARGLU1 interactions	CHERP BRD3 UBE2O BRD4 DDX23 SEC63 RPA2	3.58e-05	176	104	7	int:ARGLU1
Interaction	AURKB interactions	CUL3 CHERP LARP1 NUP214 ADGRV1 CCT6A BRD4 BYSL MACF1 STIP1 TAF1 DDX24 RPA2 HECTD1	3.63e-05	761	104	14	int:AURKB
Interaction	ELOA interactions	USP53 CUL3 BRD4 DDX23 PARN RPA2 HECTD1 AFF4	3.68e-05	242	104	8	int:ELOA
Interaction	NOP56 interactions	USP53 CUL3 LARP1 BRD3 BRD4 DDX23 PARN STIP1 DDX24 RPA2 HECTD1 AFF4	3.78e-05	570	104	12	int:NOP56
Interaction	DDX23 interactions	CHERP CWC22 BRD4 ZNF638 DDX23 PARN TAF1 DDX24 RPA2 RSBN1L AFF4	3.79e-05	480	104	11	int:DDX23
Interaction	PARP1 interactions	CUL3 CHERP LEMD3 BRD3 S100A9 CCT6A MLF2 UBE2O BRD4 HPF1 BYSL SMARCA1 PARN STIP1 DDX39A RPA2 HECTD1 RSBN1L AFF4	3.91e-05	1316	104	19	int:PARP1
Interaction	USP48 interactions	MCMBP LARP1 SCGN MYEF2 S100A9 CCT6A SARS1 BRD4 AP3B2 TOLLIP STIP1 RPA2 DDX39B	3.98e-05	668	104	13	int:USP48
Interaction	TRIR interactions	CWC22 UBE2O BRD4 HTATSF1 RPA2	4.03e-05	74	104	5	int:TRIR
Interaction	SNRNP70 interactions	CUL3 CHERP LARP1 CWC22 MYEF2 UBE2O BRD4 BYSL ZNF638 TOLLIP DDX23 HTATSF1 DDX24 HECTD1 DDX39B RSBN1L	4.30e-05	984	104	16	int:SNRNP70
Interaction	LAS1L interactions	CUL3 BRD4 DDX23 STIP1 TAF1 RPA2 HECTD1	4.44e-05	182	104	7	int:LAS1L
Interaction	GTPBP1 interactions	CUL3 UBE2O QTRT1 RPA2 HECTD1 SMG6	4.46e-05	124	104	6	int:GTPBP1
Interaction	EFTUD2 interactions	CUL3 MCMBP LARP1 CCT6A SERPINB6 UBE2O SARS1 BRD4 BYSL ZNF638 DDX23 HTATSF1 MACF1 STIP1 DDX24 RPA2 NUDC HECTD1 DDX39B GOLGB1	4.48e-05	1449	104	20	int:EFTUD2
Interaction	EAPP interactions	CWC22 BRD4 BYSL DDX23 DDX39A	4.59e-05	76	104	5	int:EAPP
Interaction	TAF15 interactions	CUL3 CHERP LARP1 UBE2O NFE2L2 BRD4 DDX23 HTATSF1 TAF1 RPA2	4.97e-05	408	104	10	int:TAF15
Interaction	PHF2 interactions	CUL3 BRD3 BRD4 DDX23 RPA2	5.20e-05	78	104	5	int:PHF2
Interaction	TRRAP interactions	CUL3 NUP214 BRD4 EPC1 BYSL ZNF638 DDX23 HTATSF1 ZSCAN2 SEC63 DDX39A DDX24 RPA2 HECTD1	5.44e-05	790	104	14	int:TRRAP
Interaction	ATM interactions	CUL3 ZNF821 MAP3K4 NFE2L2 BRD4 AP3B2 APPL1 TAF1 RPA2	5.71e-05	333	104	9	int:ATM
Interaction	HERC2 interactions	CHERP MYO9B MLF2 SERPINB6 BRD4 MACF1 TAF1 DDX39A RPA2 HECTD1 DDX39B	5.78e-05	503	104	11	int:HERC2
Interaction	HELLS interactions	USP53 CUL3 BRD3 BRD4 DDX23 STIP1 RPA2	6.22e-05	192	104	7	int:HELLS
Interaction	NKAP interactions	BRD3 MYEF2 UBE2O DDX23 HECTD1 RSBN1L	6.32e-05	132	104	6	int:NKAP
Interaction	NUP50 interactions	CUL3 SPOPL LEMD3 NUP214 POLR3C BRD4 HTATSF1 TAF1 RPA2	6.86e-05	341	104	9	int:NUP50
Interaction	SRSF7 interactions	CHERP LARP1 CWC22 S100A9 BRD4 ZNF638 DDX23 HTATSF1 STIP1 DDX39B	6.99e-05	425	104	10	int:SRSF7
Interaction	RPN1 interactions	CUL3 LEMD3 SLC6A15 ADCY9 POLR3C CCT6A UBE2O STIP1 SEC63 DDX39A RPA2 HECTD1 DDX39B GOLGB1	7.50e-05	814	104	14	int:RPN1
Interaction	BCAS2 interactions	BRD3 CWC22 BRD4 DDX23 HTATSF1 STIP1 RPA2 HECTD1	7.94e-05	270	104	8	int:BCAS2
Interaction	SRRM1 interactions	CUL3 BRD3 UBE2O BRD4 ZNF638 DDX23 HTATSF1 RPA2 DDX39B	8.01e-05	348	104	9	int:SRRM1
Cytoband	19p13.1	CHERP MYO9B BRD4	1.87e-04	48	105	3	19p13.1
GeneFamily	DEAD-box helicases	DDX12P DDX23 DDX43 DDX39A DDX24 DDX39B	9.73e-09	42	67	6	499
GeneFamily	Bone morphogenetic proteins\|Astacins	BMP5 BMP15	7.28e-04	11	67	2	455
GeneFamily	EF-hand domain containing	GNPTAB SCGN S100A9 ANKEF1 MACF1	1.31e-03	219	67	5	863
GeneFamily	Dyneins, axonemal	DNAH1 DNAH17	1.77e-03	17	67	2	536
Coexpression	HOUNKPE_HOUSEKEEPING_GENES	CUL3 MCMBP PSMB7 LARP1 BRD3 POLR3C MLF2 SARS1 BRD4 TOLLIP DDX23 HTATSF1 APPL1 PARN STIP1 RPA2 NUDC KDM4B	5.25e-07	1129	105	18	M42508
Coexpression	HOUNKPE_HOUSEKEEPING_GENES	CUL3 MCMBP PSMB7 LARP1 BRD3 POLR3C MLF2 SARS1 BRD4 TOLLIP DDX23 HTATSF1 APPL1 PARN STIP1 RPA2 NUDC KDM4B	7.56e-07	1158	105	18	MM1338
Coexpression	GSE2770_UNTREATED_VS_TGFB_AND_IL4_TREATED_ACT_CD4_TCELL_48H_UP	USP53 POLR3C S100A9 RIMKLB TOLLIP ZSCAN2 SEC63	2.96e-06	154	105	7	M6088
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Neuronal-neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN SLC6A15 GPRIN1 DNAH1 AP3B2 SMARCA1	4.23e-06	179	105	6	479116ac65488c60104a053530830763ec1f95b2
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN SLC6A15 GPRIN1 DNAH1 AP3B2 SMARCA1	4.23e-06	179	105	6	1dfc0cb8b369aef35c59f3d4c52603dc9f3728c1
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN SLC6A15 GPRIN1 DNAH1 AP3B2 SMARCA1	4.23e-06	179	105	6	69a1b3b05c921de6343ffe6ad998aa2b804312a7
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN MYO7B ADGRV1 TEX11 DNAH1 UNC79	4.96e-06	184	105	6	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN MYO7B ADGRV1 TEX11 DNAH1 UNC79	4.96e-06	184	105	6	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN MYO7B ADGRV1 TEX11 DNAH1 UNC79	4.96e-06	184	105	6	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	facs-Pancreas-Endocrine-3m-Epithelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCGN GPRIN1 MYEF2 CCT6A AP3B2 SMARCA1	6.14e-06	191	105	6	657297cd19d05a7e7bb74fc3a086fbd95f47aae4
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-Radial_glial-gliogenic/outer_RGCs_and_astrocytes\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	DIPK1C NAPEPLD ADGRV1 SERPINB6 SLCO1C1 NFE2L2	6.72e-06	194	105	6	7c6c0376603e5fcb64814fd6204d153629c2fbf5
ToppCell	facs-Large_Intestine-Distal-18m-Epithelial-intestinal_crypt_stem_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PSMB7 CCT6A SCPEP1 STIP1 DDX39A DDX39B	6.92e-06	195	105	6	44ac99e33b20a377009b8fef16142050a3e1da51
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-6_mon\|organoid_Paulsen_bioRxiv / Sample Type, Dataset, Time_group, and Cell type.	DIPK1C COLGALT2 ADGRV1 SCGN SERPINB6 SLCO1C1	7.33e-06	197	105	6	58b957efd006f43c2fe55071d5c6d06c2e367e72
ToppCell	cellseq-Mesenchymal-Fibroblastic\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	USP53 SERPINA3 LAMA2 BMP5 MACF1 BICC1	7.99e-06	200	105	6	8978867bf69c830b1e48cac2ad6b512dbe60f149
ToppCell	Substantia_nigra-Macroglia-OLIGODENDROCYTE-O2-Tfr-Oligodendrocyte.Tfr.Ndrg2_(Ndrg2)-\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	CRYBG2 C16orf96 FAM186A DDX43	1.41e-05	62	105	4	f7697057fb5568368ec7edead2bcdd25ede7627b
ToppCell	Substantia_nigra-Macroglia-OLIGODENDROCYTE-O2-Tfr-Oligodendrocyte.Tfr.Ndrg2_(Ndrg2)\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	CRYBG2 C16orf96 FAM186A DDX43	1.41e-05	62	105	4	19867e62ca7e024572192a2654e2eb8f226bdd60
ToppCell	ILEUM-non-inflamed-(3)_MNP-(3)_moDC\|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	MYO9B TBC1D8 MACF1 HECTD1 GOLGB1	1.71e-05	135	105	5	b7a792a7c0c22d8b703509f134115f0e394d7de0
ToppCell	normal_Lymph_Node-Myeloid_cells-CD163+CD14+_DCs\|Myeloid_cells / Location, Cell class and cell subclass	COLGALT2 CWC22 DNAH17 HPF1 HTATSF1	2.75e-05	149	105	5	a34d095b8e0fe59d69d84e4fd2fe4ccb82f92e4f
ToppCell	356C-Fibroblasts-Fibroblast-E-\|356C / Donor, Lineage, Cell class and subclass (all cells)	COLGALT2 LRIG3 FAM186A AP3B2 BICC1	6.43e-05	178	105	5	a493a277d175e5e153410a745b26ebe2e0839ea0
ToppCell	356C-Fibroblasts-Fibroblast-E\|356C / Donor, Lineage, Cell class and subclass (all cells)	COLGALT2 LRIG3 FAM186A AP3B2 BICC1	6.43e-05	178	105	5	371218babddfd3d8a7bb82a46ce65327ee3fcf12
ToppCell	10x5'v1-week_12-13-Mesenchymal_myocytic\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	DIPK1C BMP5 SLCO1C1 SNX7 SMARCA1	7.51e-05	184	105	5	437bc6c983849c1c3ff85f0dee091cf7010a4665
ToppCell	COVID-19_Severe-gd_T\|COVID-19_Severe / Disease condition and Cell class	CRYBG2 MYO9B GNPTAB LAMA2 MACF1	7.51e-05	184	105	5	791f1bcb954aadc63d4117c400537d036f68734d
ToppCell	10x5'v1-week_12-13-Mesenchymal_myocytic-stroma\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	DIPK1C BMP5 SLCO1C1 SNX7 SMARCA1	7.51e-05	184	105	5	d1d5dd1701dff4eedf1cebbb9f4cd603aa0009c1
ToppCell	CV-Moderate-7\|Moderate / Virus stimulation, Condition and Cluster	NAPEPLD GNPTAB MAP3K4 MACF1 SEC63	7.71e-05	185	105	5	a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCell	10x5'v1-week_12-13-Mesenchymal_myocytic-stroma-muscle\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	DIPK1C BMP5 SLCO1C1 SNX7 SMARCA1	7.91e-05	186	105	5	fbc4ba4a7a8e5902a1b0add52ece0d6da85a8a5f
ToppCell	CV-Moderate-7\|CV / Virus stimulation, Condition and Cluster	NAPEPLD GNPTAB MAP3K4 MACF1 SEC63	7.91e-05	186	105	5	8571956890fc9894d766ba294a28e376b4aba428
ToppCell	Control-Fibroblasts-Alveolar_FB\|Control / group, cell type (main and fine annotations)	USP53 LAMA2 BMP5 MACF1 BICC1	8.11e-05	187	105	5	92d468dde81125d51daf7abd4703741abe1ab91c
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NAPEPLD ADGRV1 MYRFL DNAH17 BICC1	8.11e-05	187	105	5	c41a2c81dd2ceef303f39f699032aa7d6ea67cf0
ToppCell	facs-Pancreas-Endocrine-3m-Epithelial-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCGN GPRIN1 MYEF2 CCT6A SMARCA1	8.32e-05	188	105	5	e99e3765b48392c987cf0c5ccbded0655637d7b7
ToppCell	renal_cortex_nuclei-Adult_normal_reference\|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	USP53 TBC1D8 ZNF638 GOLGB1 KDM4B	8.53e-05	189	105	5	a48df46274d51e84ffb40264646de7346104efb9
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPRC5C GPRIN1 BMP5 SMARCA1 NPAS4	8.74e-05	190	105	5	1d8e169d2448a34180c415843bb49aa45ed540c5
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	USP53 LAMA2 BMP5 MACF1 BICC1	8.96e-05	191	105	5	6688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	USP53 LAMA2 BMP5 MACF1 BICC1	9.18e-05	192	105	5	99ce9e3c4c50cf64ebb62145f2b5420efa0db309
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	SPOPL LEMD3 ADGRV1 APPL1 HECTD1	9.41e-05	193	105	5	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	USP53 LAMA2 BMP5 MACF1 BICC1	9.41e-05	193	105	5	99525545552b371c86b18b6ea6f4897dc6e9a9ec
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	USP53 LAMA2 BMP5 MACF1 BICC1	9.41e-05	193	105	5	b3ad5ff480d99217f36cc7471e5a96a519ddb409
ToppCell	droplet-Lung-21m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l49\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LAMA2 BMP5 RIMKLB SMARCA1 BICC1	9.64e-05	194	105	5	7826fe5eb254ac032de0d978f39585a40e0b3ee4
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN RAD51AP2 MACF1 GOLGB1 AFF4	9.87e-05	195	105	5	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	nucseq-Mesenchymal-Fibroblastic\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	USP53 LAMA2 BMP5 MACF1 BICC1	1.01e-04	196	105	5	7d8505dac15fa59935ccf592afc54b04c4c6554f
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	USP53 SERPINA3 LAMA2 BMP5 MACF1	1.04e-04	197	105	5	94a9603cbd3516fbcce871909693b88f20d41713
ToppCell	(5)_Fibroblasts-(5)_Fibroblast-E\|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)	LAMA2 COLGALT2 NFE2L2 SCPEP1 BICC1	1.04e-04	197	105	5	9b1c1d72c5a8c90d71ae31e4c198d2276872eaa0
ToppCell	severe-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	TEX11 MAP3K4 MACF1 DDX24 DDX39B	1.04e-04	197	105	5	57ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCell	CV-Mild-2\|CV / Virus stimulation, Condition and Cluster	CCT6A BYSL STIP1 QTRT1 DDX39A	1.04e-04	197	105	5	dc1cfba2ee66c62b53accefbfce3025cd760524a
ToppCell	Brain_organoid-organoid_Velasco_nature-3_mon-Radial_glial-oRG\|3_mon / Sample Type, Dataset, Time_group, and Cell type.	DIPK1C ADGRV1 SERPINB6 SLCO1C1 NFE2L2	1.06e-04	198	105	5	72dc49aa107d0cc6206eb67b577c73e190855125
ToppCell	nucseq-Mesenchymal\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	USP53 LAMA2 BMP5 MACF1 BICC1	1.06e-04	198	105	5	8f52243ca8b9ba68a75ae411506a3a6de258eb97
ToppCell	cellseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	USP53 SERPINA3 LAMA2 BMP5 MACF1	1.06e-04	198	105	5	f1374f7a50244d59c766ac41f44c08c9117407d2
ToppCell	mild-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	GNPTAB MACF1 DDX24 GOLGB1 SMG6	1.09e-04	199	105	5	f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell	distal-mesenchymal-Alveolar_Fibroblast-2\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	USP53 SERPINA3 LAMA2 BMP5 MACF1	1.09e-04	199	105	5	28c1722deef3b8347371c7359be7c64b95780de3
ToppCell	Brain_organoid-organoid_Velasco_nature-6_mon-Radial_glial-oRG\|6_mon / Sample Type, Dataset, Time_group, and Cell type.	COLGALT2 ADGRV1 SERPINB6 SLCO1C1 NFE2L2	1.09e-04	199	105	5	9762611a142a8e45d8ecbbedbd4a0cb044c51145
ToppCell	cellseq-Mesenchymal-Fibroblastic-Fibroblastic_2\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	USP53 SERPINA3 LAMA2 BMP5 MACF1	1.09e-04	199	105	5	66a79732caf2f04c09b4d9832377aa01ca477677
ToppCell	CV-Mild-2\|Mild / Virus stimulation, Condition and Cluster	CCT6A BYSL STIP1 QTRT1 DDX39A	1.09e-04	199	105	5	d88cc07053a852e6c468538a0a851ffa09f97a0d
ToppCell	Brain_organoid-organoid_Velasco_nature-3_mon-Radial_glial\|3_mon / Sample Type, Dataset, Time_group, and Cell type.	DIPK1C ADGRV1 SERPINB6 SLCO1C1 NFE2L2	1.09e-04	199	105	5	0fee11bd72b27202f8d9fa4daba831ea9c8a61b2
ToppCell	Frontal_cortex-Neuronal\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	SLC6A15 GPRIN1 UBE2O AP3B2 DDX24	1.09e-04	199	105	5	f88039d862f3bfa01dc39d2de4f3f548dc5a0e61
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Radial_glial\|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.	DIPK1C ADGRV1 SERPINB6 SLCO1C1 NFE2L2	1.09e-04	199	105	5	6fd9774f18da3e6f114427f55a8879ac90c41350
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Radial_glial-oRG\|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.	DIPK1C ADGRV1 SERPINB6 SLCO1C1 NFE2L2	1.09e-04	199	105	5	151bda6821b52cfb4491474892ecb45781522837
ToppCell	TCGA-Bile_Duct-Primary_Tumor-Cholangiocarcinoma-Intrahepatic\|TCGA-Bile_Duct / Sample_Type by Project: Shred V9	LARP1 GPRIN1 TBC1D8 ANKEF1 BICC1	1.11e-04	200	105	5	1fa8422fd820d21e285a7e7c4c6fbd8b7277d2af
ToppCell	COVID-19\|World / Disease, condition lineage and cell class	EPC1 MACF1 DDX24 GOLGB1 AFF4	1.11e-04	200	105	5	7dec470c379cd89f05a0f37c8628b21f136e52f0
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sncg-Sncg_Vip_Itih5\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	DOCK2 DIPK1C SCGN DYSF	1.64e-04	116	105	4	605bd4fdf547cc41783e99cd78425760ef6461ef
ToppCell	Substantia_nigra-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	LAMA2 GPRC5C BMP5 ANKEF1	1.87e-04	120	105	4	e60b74758c8290919b326904ad841962256b72ec
ToppCell	Substantia_nigra-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2-MURAL_Mural.Rgs5Acta2.Kcnj8_(Mural.Rgs5Acta2.Kcnj8)-\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	LAMA2 GPRC5C BMP5 ANKEF1	1.87e-04	120	105	4	3e1ae5a5422729d484a90d72f779833fe3473fa8
ToppCell	Substantia_nigra-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2-MURAL_Mural.Rgs5Acta2.Kcnj8_(Mural.Rgs5Acta2.Kcnj8)\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	LAMA2 GPRC5C BMP5 ANKEF1	1.87e-04	120	105	4	24d5e86931a857bb87684392172bf04294a1a46a
Disease	prostate specific antigen measurement	SERPINA3 LAMA2 SLC6A15 TEX11 DYSF SMG6	5.01e-05	188	102	6	EFO_0004624
Disease	urate measurement	TOP6BL ADGRV1 DYSF DNAH1 POLR3C TBC1D8 BMP5 MLF2 STIP1 NUDC BICC1 KDM4B	6.23e-05	895	102	12	EFO_0004531
Disease	reticulocyte measurement	MYO9B PSMB7 LARP1 BRD3 TBC1D8 NOL4L UBE2O RIMKLB BRD4 DNAH17 DDX39A DDX39B SMG6	7.00e-05	1053	102	13	EFO_0010700
Disease	arteriovenous malformations of the brain (implicated_via_orthology)	LEMD3 SARS1	2.46e-04	7	102	2	DOID:0060688 (implicated_via_orthology)
Disease	reticulocyte count	MYO9B PSMB7 LARP1 BRD3 TBC1D8 NOL4L UBE2O RIMKLB DNAH17 DDX39A DDX39B SMG6	2.64e-04	1045	102	12	EFO_0007986
Disease	LDL cholesterol change measurement, response to simvastatin, response to fenofibrate	SNX7 BICC1	3.27e-04	8	102	2	EFO_0007804, GO_1901557, GO_1903491
Disease	lean body mass	LAMA2 COLGALT2 ADGRV1 ADCY9 BMP5 ZNF638 RSBN1L	3.54e-04	379	102	7	EFO_0004995
Disease	total hip arthroplasty, osteoarthritis	COLGALT2 LRIG3 BMP5	4.17e-04	42	102	3	EFO_0009806, MONDO_0005178
Disease	Polycystic Kidney, Autosomal Dominant	BRD4 BICC1	4.19e-04	9	102	2	C0085413
Disease	mean corpuscular hemoglobin concentration	MYO9B LARP1 C16orf96 BRD3 ADCY9 NFE2L2 BRD4 BYSL ZNF638 MACF1 DDX39A GOLGB1	4.36e-04	1105	102	12	EFO_0004528
Disease	sexual dimorphism measurement	ANKRD31 MYO9B TOP6BL COLGALT2 DYSF ADCY9 ZNF638 MACF1 ZSCAN2 PARN NUDC NPAS4	4.39e-04	1106	102	12	EFO_0021796
Disease	Childhood Medulloblastoma	BRD3 BRD4 KDM4B	4.48e-04	43	102	3	C0278510
Disease	Melanotic medulloblastoma	BRD3 BRD4 KDM4B	4.48e-04	43	102	3	C1275668
Disease	Medullomyoblastoma	BRD3 BRD4 KDM4B	4.48e-04	43	102	3	C0205833
Disease	Desmoplastic Medulloblastoma	BRD3 BRD4 KDM4B	4.48e-04	43	102	3	C0751291
Disease	Adult Medulloblastoma	BRD3 BRD4 KDM4B	4.48e-04	43	102	3	C0278876
Disease	platelet crit	ANKRD31 SPATA6L MYO9B PSMB7 ADGRV1 SCGN NOL4L SERPINB6 RPA2 NUDC SMG6	4.58e-04	952	102	11	EFO_0007985
Disease	Medulloblastoma	BRD3 BRD4 KDM4B	6.99e-04	50	102	3	C0025149
Disease	response to simvastatin, total cholesterol change measurement, response to fenofibrate	SLC6A15 SCGN BICC1	7.40e-04	51	102	3	EFO_0007806, GO_1901557, GO_1903491
Disease	polyp of colon	BMP5 MLF2 XRRA1	9.73e-04	56	102	3	MONDO_0021400
Disease	response to olanzapine	SPOPL ADGRV1	1.21e-03	15	102	2	GO_0097333
Disease	testosterone measurement	MYO9B ICE2 C16orf96 SCGN CWC22 ADCY9 TBC1D8 BMP5 NFE2L2 FAM186A MACF1 NUDC	1.51e-03	1275	102	12	EFO_0004908
Disease	muscular dystrophy (is_implicated_in)	LAMA2 DYSF	1.56e-03	17	102	2	DOID:9884 (is_implicated_in)
Disease	cholesterol:total lipids ratio, low density lipoprotein cholesterol measurement	ANKRD31 SCGN MACF1 NUDC	1.60e-03	144	102	4	EFO_0004611, EFO_0020943
Disease	Antihypertensive use measurement	MYO9B ADCY9 BICC1 KDM4B SMG6	2.31e-03	265	102	5	EFO_0009927
Disease	cortical surface area measurement	RELN SLC9A8 MYO9B LAMA2 SLC6A15 ACTRT2 ADGRV1 DYSF MLF2 NOL4L MACF1 SMG6	2.35e-03	1345	102	12	EFO_0010736
Disease	creatinine measurement	ICE2 LAMA2 SLC6A15 ADGRV1 TEX11 TBC1D8 NFE2L2 AP3B2 NUDC RSBN1L	2.35e-03	995	102	10	EFO_0004518
Disease	sex interaction measurement, cerebral amyloid angiopathy	ADCY9 ELMOD1	2.38e-03	21	102	2	EFO_0006790, EFO_0008343
Disease	muscular dystrophy (implicated_via_orthology)	LAMA2 DYSF	2.38e-03	21	102	2	DOID:9884 (implicated_via_orthology)
Disease	Ovarian Failure, Premature	NFE2L2 BMP15	2.38e-03	21	102	2	C0085215
Disease	low density lipoprotein cholesterol measurement, response to escitalopram, response to citalopram	RELN ACTRT2	3.11e-03	24	102	2	EFO_0004611, EFO_0006329, EFO_0007871
Disease	pulse pressure measurement	PSMB7 DYSF CWC22 S100A9 LRIG3 CCT6A NFE2L2 ZNF638 ARMH3 BICC1 KDM4B SMG6	3.11e-03	1392	102	12	EFO_0005763
Disease	snoring measurement	ADGRV1 MACF1 SMG6	3.12e-03	84	102	3	EFO_0008341

Protein segments in the cluster

Peptide	Gene	Start	Entry
KLLAPDMFTESDDMF	PRPF4B	626	Q13523
KQDEPIDLFMIEIME	CCT6A	181	P40227
RVTFDAEAMNKESPM	SMG6	351	Q86US8
KMDICPLQFEEMIDR	EPC1	131	Q9H2F5
DVFEMRFAKMPDEPV	BRD3	406	Q15059
EDPMDIMEFNRVREK	ELMOD1	291	Q8N336
LQDVFEMRFAKMPDE	BRD4	446	O60885
FILPDQDKMEEVEAM	SERPINA3	276	P01011
PRENREKMAEVMFEN	ACTRT2	116	Q8TDY3
EKMAEVMFENFGVPA	ACTRT2	121	Q8TDY3
VLVEKIFDLAFMPAM	BPIFB4	566	P59827
KFMQDPMEIFVDDET	DDX39B	241	Q13838
FMQDPMEVFVDDETK	DDX39A	241	O00148
IMIEENDDPRGIFMF	ADGRV1	3901	Q8WXG9
DFDDFMMPFQKNITE	ANKEF1	751	Q9NU02
FDIINMLMGFDKAEL	ARMH3	121	Q5T2E6
LMFDMKEEIEVDPQF	BICC1	356	Q9H694
SFFRQRMFSPMEEKE	AFF4	686	Q9UHB7
LMAPVFMSENEFKKE	AP3B2	971	Q13367
IEKEEKDSFFPMDDM	RAD51AP2	856	Q09MP3
AAMAVFEDKFRPDME	PSMB7	176	Q99436
DEERLKAFAPIQEMM	HPF1	261	Q9NWY4
EPFFNKLFLMRVMDI	PARN	416	O95453
LKIRNMFDPVMEIGD	LEMD3	786	Q9Y2U8
NFRMQDPALMIDGKE	ANKRD31	431	Q8N7Z5
DFLFDEEMEQMDGRK	LARP1	606	Q6PKG0
MQELQDMFPEEFDKT	GNPTAB	966	Q3T906
FEESKTRFHLPMDMV	NRAP	621	Q86VF7
RMHVMPEDDVFFIVD	LRIG3	651	Q6UXM1
MMFPITQFKERDLKE	APPL1	111	Q9UKG1
VLNVFKMDPNFMENE	CWC22	381	Q9HCG8
AKFLPRGMEEFMERE	BMP15	246	O95972
LPVVDFNEMMSKEQF	NFE2L2	476	Q16236
MNDQLMFLERAFIDP	FOLH1B	356	Q9HBA9
LENFLMVDKDQIFME	MYRFL	526	Q96LU7
MTFRPTMEEFKDFNK	KDM4B	16	O94953
DAMIPEREMKDFQFR	NUP214	6	P35658
LNADLMMFAHKDPRE	LAMA2	251	P24043
ADRMIDMGFEPDVQK	DDX23	551	Q9BUQ8
MNDSEGMDPERLKAF	NOL4L	176	Q96MY1
FMEEMTRKQPDVDRV	MACF1	6926	Q9UPN3
PVGRIAFDMFMEDKT	RELN	2691	P78509
VIIKNMFHPMDFEDD	HTATSF1	266	O43719
MFVENKAFSMDEPVA	GPRC5C	336	Q9NQ84
DNMFLEETPVEDIFM	NPAS4	701	Q8IUM7
VFQGMLMADPAKVED	DNAH1	2446	Q9P2D7
QMEAFRDGFNKVFPM	HECTD1	2461	Q9ULT8
AVFMDKPEEFISEMD	ICE2	361	Q659A1
AELRKATIPIFFDMM	DOCK2	1101	Q92608
QFVARNGPEFEKMTM	CHERP	21	Q8IWX8
NMLDKVHPERMDIFA	C16orf96	171	A6NNT2
LEEMEQADFTMLPTF	DNAH17	296	Q9UFH2
MVLFRFMQEKDVFER	CUL3	416	Q13618
QMEAPQKEMFEFSRR	CRYBG2	46	Q8N1P7
LEFTFQKRDLPQMMD	DDX12P	691	Q92771
QILFEFAKEMMRVVD	ADCY9	1136	O60503
MVMSFVNLVERDKDF	BMP5	156	P22003
EVKIDPNMFADGQMD	DDX24	31	Q9GZR7
MFFKMKNEIDNDPES	FAM186A	1	A6NE01
PDKMGFDEIFMINLK	COLGALT2	336	Q8IYK4
SSDDRNPMFLEKMDF	GPRIN1	141	Q7Z2K8
EVDGFVKDMMELVQP	SCGN	221	O76038
FRAEDLPQMDDAVMD	DYSF	386	O75923
DPEDERAIEMFMNKN	BYSL	126	Q13895
DEADKMLDMGFEPQI	DDX43	396	Q9NXZ2
IDVDMAFFEPKMREI	DIPK1C	296	Q0P6D2
VKFRCMIQDMFDPEF	MCMBP	66	Q9BTE3
MFRFMRDVEPEDPMF	MLF2	1	Q15773
GELMAMKEIRFQPND	MAP3K4	1366	Q9Y6R4
HLSPMEMERFAEEFV	RSBN1L	371	Q6PCB5
PFFMRKEVMQEVAQL	SARS1	226	P49591
DKFMEDLKDMLGFAP	SLC6A15	551	Q9H2J7
AFPIMIQESMRFEKV	SPATA6L	46	Q8N4H0
DKQLSFEEFIMLMAR	S100A9	71	P06702
EKRFPDFVRDFMGAM	QTRT1	366	Q9BXR0
DKDARAAFIRDEMMP	SMARCA1	266	P28370
EARLAERKFMNPFNM	STIP1	116	P31948
FQMIFEVDEKPRTLM	TOP6BL	106	Q8N6T0
QFLFDRPMHVKMDDK	MYEF2	296	Q9P2K5
NVFVNMEEDFMKPVI	SCPEP1	336	Q9HB40
EMFFMRTPQDLTGKD	TAF1	661	P21675
MMDEEEVEVSLPRFK	SERPINB6	261	P35237
KEEEMFRPNMFFLLL	SLC9A8	116	Q9Y2E8
MFNRKFMEELFKPQE	OSCP1	56	Q8WVF1
EILKKFMDQHPEMDF	NUDC	311	Q9Y266
NRPEEFMEMNNFIEL	SNX7	181	Q9UNH6
MLERHERFKPEMFAE	USP53	196	Q70EK8
MNMDARPTEGFEKLQ	TTC30B	296	Q8N4P2
MFENESRKIFSEMPE	ZSCAN2	151	Q7Z7L9
LVAFKIMPLEDMNEF	RPA2	141	P15927
EDFAMIPAKEAKDML	POLR3C	381	Q9BUI4
NPEMELEKVRMEFEL	TMEM247	101	A6NEH6
VEINDLDPEVFKEMM	SPOPL	241	Q6IQ16
FSMFLNLDEVFKVME	TBC1D8	231	O95759
ENAKIMEMARDFLPS	SLCO1C1	331	Q9NYB5
EEDLKAIQDMFPNMD	TOLLIP	231	Q9H0E2
EGIMVKTFEDRMDLF	UBE2O	971	Q9C0C9
RMKIPETLEEDQQFM	SEC63	311	Q9UGP8
AVQCDKDPVMMREFF	TEX11	646	Q8IYF3
FAKMIDEAEVLEFPM	RIMKLB	141	Q9ULI2
MNMDARPTEGFEKLQ	TTC30A	296	Q86WT1
LEEQARQAMMKTDFP	ZNF821	21	O75541
FMLQSKPRMLEDSDE	XRRA1	296	Q6P2D8
MAPENMNIKDEEAIF	ZNF638	976	Q14966
QEMAKFEEPDILFNM	UNC79	961	Q9P2D8
MKVFLEDTGQDFPLM	GOLGB1	611	Q14789
DTEMVEKVFGFLPAM	MYO7B	911	Q6PIF6
FERLKQAMEMVGFLP	MYO9B	381	Q13459
DFREKNMDYMRPDIV	MYO9B	646	Q13459
MVEMDELIFLTDPIF	NAPEPLD	136	Q6IQ20