Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	calcium- and calmodulin-responsive adenylate cyclase activity	ADCY3 ADCY5	1.04e-04	5	65	2	GO:0008294
GeneOntologyMolecularFunction	protein serine kinase activity	TLK2 ILK LATS2 MTOR CLK2 OBSCN CASK	1.74e-04	363	65	7	GO:0106310
Domain	ARM-type_fold	TNPO1 DOCK2 DOCK3 JUP URB1 MTOR AP1G2 PSMD2 CUL7 MEI1 HEATR5B	1.59e-08	339	63	11	IPR016024
Domain	ARM-like	TNPO1 DOCK2 JUP MTOR AP1G2 PSMD2 CUL7 MEI1 HEATR5B	2.89e-07	270	63	9	IPR011989
Domain	-	TNPO1 JUP MTOR AP1G2 PSMD2 CUL7 HEATR5B	9.59e-06	222	63	7	1.25.10.10
Domain	DOCK_N	DOCK2 DOCK3	1.11e-04	5	63	2	PF16172
Domain	DOCK_N	DOCK2 DOCK3	1.11e-04	5	63	2	IPR032376
Domain	AC_N	ADCY3 ADCY5	3.09e-04	8	63	2	IPR032628
Domain	Adcy	ADCY3 ADCY5	3.09e-04	8	63	2	IPR030672
Domain	AC_N	ADCY3 ADCY5	3.09e-04	8	63	2	PF16214
Domain	DOCK_C	DOCK2 DOCK3	6.04e-04	11	63	2	IPR010703
Domain	DHR-1_domain	DOCK2 DOCK3	6.04e-04	11	63	2	IPR027007
Domain	DHR_2	DOCK2 DOCK3	6.04e-04	11	63	2	PS51651
Domain	DHR_1	DOCK2 DOCK3	6.04e-04	11	63	2	PS51650
Domain	DOCK-C2	DOCK2 DOCK3	6.04e-04	11	63	2	PF14429
Domain	DHR-2	DOCK2 DOCK3	6.04e-04	11	63	2	IPR027357
Domain	DHR-2	DOCK2 DOCK3	6.04e-04	11	63	2	PF06920
Domain	DOCK	DOCK2 DOCK3	6.04e-04	11	63	2	IPR026791
Domain	HEAT	TNPO1 JUP MTOR	9.89e-04	58	63	3	IPR000357
Domain	Ser/Thr_kinase_AS	TLK2 ILK LATS2 CLK2 OBSCN CASK	1.27e-03	357	63	6	IPR008271
Domain	PROTEIN_KINASE_ST	TLK2 ILK LATS2 CLK2 OBSCN CASK	1.36e-03	362	63	6	PS00108
Domain	A/G_cyclase_CS	ADCY3 ADCY5	1.47e-03	17	63	2	IPR018297
Domain	Nucleotide_cyclase	ADCY3 ADCY5	1.65e-03	18	63	2	IPR029787
Domain	-	ADCY3 ADCY5	1.65e-03	18	63	2	3.30.70.1230
Domain	HEAT_REPEAT	TNPO1 MTOR HEATR5B	1.70e-03	70	63	3	PS50077
Domain	GUANYLATE_CYCLASE_1	ADCY3 ADCY5	1.85e-03	19	63	2	PS00452
Domain	Guanylate_cyc	ADCY3 ADCY5	1.85e-03	19	63	2	PF00211
Domain	GUANYLATE_CYCLASE_2	ADCY3 ADCY5	1.85e-03	19	63	2	PS50125
Domain	A/G_cyclase	ADCY3 ADCY5	1.85e-03	19	63	2	IPR001054
Domain	CYCc	ADCY3 ADCY5	1.85e-03	19	63	2	SM00044
Domain	Kinase-like_dom	TLK2 ILK LATS2 MTOR CLK2 OBSCN CASK	2.26e-03	542	63	7	IPR011009
Domain	SH3_2	DOCK2 DOCK3 CASK	3.07e-03	86	63	3	IPR011511
Domain	SH3_2	DOCK2 DOCK3 CASK	3.07e-03	86	63	3	PF07653
Domain	PROTEIN_KINASE_ATP	TLK2 ILK LATS2 CLK2 OBSCN CASK	4.44e-03	459	63	6	PS00107
Domain	Prot_kinase_dom	TLK2 ILK LATS2 CLK2 OBSCN CASK	6.02e-03	489	63	6	IPR000719
Domain	SH3	DOCK2 DOCK3 OBSCN CASK	6.08e-03	216	63	4	SM00326
Domain	SH3	DOCK2 DOCK3 OBSCN CASK	6.08e-03	216	63	4	PS50002
Domain	PROTEIN_KINASE_DOM	TLK2 ILK LATS2 CLK2 OBSCN CASK	6.25e-03	493	63	6	PS50011
Domain	SH3_domain	DOCK2 DOCK3 OBSCN CASK	6.49e-03	220	63	4	IPR001452
Pubmed	Disruption of Epac1 protects the heart from adenylyl cyclase type 5-mediated cardiac dysfunction.	RAPGEF3 ADCY5	3.55e-06	2	66	2	27117748
Pubmed	Arrhythmic effects of Epac-mediated ryanodine receptor activation in Langendorff-perfused murine hearts are associated with reduced conduction velocity.	RAPGEF3 RYR2	3.55e-06	2	66	2	28316073
Pubmed	Upregulation of mTORC2 activation by the selective agonist of EPAC, 8-CPT-2Me-cAMP, in prostate cancer cells: assembly of a multiprotein signaling complex.	RAPGEF3 MTOR	3.55e-06	2	66	2	22173835
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	TNPO1 URB1 DDX46 MTOR YLPM1 PSMD2 CUL7 NUP205 PTCD3	3.92e-06	653	66	9	22586326
Pubmed	Early effects of Epac depend on the fine-tuning of the sarcoplasmic reticulum Ca2+ handling in cardiomyocytes.	RAPGEF3 RYR2	1.06e-05	3	66	2	29037982
Pubmed	Epac1-induced cellular proliferation in prostate cancer cells is mediated by B-Raf/ERK and mTOR signaling cascades.	RAPGEF3 MTOR	1.06e-05	3	66	2	19725049
Pubmed	Chromosomal mapping of human adenylyl cyclase genes type III, type V and type VI.	ADCY3 ADCY5	1.06e-05	3	66	2	8034296
Pubmed	MAP kinases and mTOR mediate insulin-induced phosphorylation of insulin receptor substrate-1 on serine residues 307, 612 and 632.	JUP MTOR	2.12e-05	4	66	2	14579029
Pubmed	The E3 ubiquitin ligases, HUWE1 and NEDD4-1, are involved in the post-translational regulation of the ABCG1 and ABCG4 lipid transporters.	TNPO1 JUP PSMD2	3.42e-05	33	66	3	26296893
Pubmed	mTOR associates with TFIIIC, is found at tRNA and 5S rRNA genes, and targets their repressor Maf1.	GTF3C2 MTOR	3.53e-05	5	66	2	20543138
Pubmed	Ultrasound induces hypoxia-inducible factor-1 activation and inducible nitric-oxide synthase expression through the integrin/integrin-linked kinase/Akt/mammalian target of rapamycin pathway in osteoblasts.	ILK MTOR	3.53e-05	5	66	2	17588951
Pubmed	Nucleolar disruption in dopaminergic neurons leads to oxidative damage and parkinsonism through repression of mammalian target of rapamycin signaling.	MTOR RRN3	3.53e-05	5	66	2	21228155
Pubmed	Cellular repressor of E1A-stimulated genes regulates vascular endothelial cell migration by the ILK/AKT/mTOR/VEGF(165) signaling pathway.	ILK MTOR	3.53e-05	5	66	2	21939655
Pubmed	Epac2 mediates cardiac β1-adrenergic-dependent sarcoplasmic reticulum Ca2+ leak and arrhythmia.	RAPGEF3 RYR2	3.53e-05	5	66	2	23363625
Pubmed	mTOR regulates lysosomal ATP-sensitive two-pore Na(+) channels to adapt to metabolic state.	TPCN2 MTOR	3.53e-05	5	66	2	23394946
Pubmed	Hypoxia induces BMP-2 expression via ILK, Akt, mTOR, and HIF-1 pathways in osteoblasts.	ILK MTOR	3.53e-05	5	66	2	20232298
Pubmed	AMPK, a Regulator of Metabolism and Autophagy, Is Activated by Lysosomal Damage via a Novel Galectin-Directed Ubiquitin Signal Transduction System.	TNPO1 JUP URB1 HDHD5 PSMD2 CASK NUP205	3.71e-05	484	66	7	31995728
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	DOCK3 URB1 LATS2 KMT2B MTOR TMC6 OBSCN AP1G2 HERC1 PHC2	4.22e-05	1105	66	10	35748872
Pubmed	Rictor and integrin-linked kinase interact and regulate Akt phosphorylation and cancer cell survival.	ILK MTOR	5.29e-05	6	66	2	18339839
Pubmed	Phospholipase Cε hydrolyzes perinuclear phosphatidylinositol 4-phosphate to regulate cardiac hypertrophy.	RAPGEF3 RYR2	5.29e-05	6	66	2	23540699
Pubmed	Developmental changes in gene expression of Epac and its upregulation in myocardial hypertrophy.	RAPGEF3 ADCY5	5.29e-05	6	66	2	17557924
Pubmed	Mapping of adenylyl cyclase genes type I, II, III, IV, V, and VI in mouse.	ADCY3 ADCY5	5.29e-05	6	66	2	7766992
Pubmed	Expression and regulation of adenylyl cyclase isoforms in the human adrenal gland.	ADCY3 ADCY5	5.29e-05	6	66	2	11549699
Pubmed	The RNA-binding protein HuR is a novel target of Pirh2 E3 ubiquitin ligase.	URB1 DDX46 CUL7 NUP205 PTCD3	6.32e-05	220	66	5	34091597
Pubmed	Differential expression of adenylyl cyclase mRNAs in lacrimal glands of NZB/NZW and NOD pre-autoimmune mice.	ADCY3 ADCY5	7.40e-05	7	66	2	12613887
Pubmed	The interaction of Epac1 and Ran promotes Rap1 activation at the nuclear envelope.	RAPGEF3 NUP205	7.40e-05	7	66	2	20547757
Pubmed	mTOR-dependent activation of the transcription factor TIF-IA links rRNA synthesis to nutrient availability.	MTOR RRN3	7.40e-05	7	66	2	15004009
Pubmed	MYC multimers shield stalled replication forks from RNA polymerase.	TNPO1 TLK2 JUP URB1 YLPM1 PSMD2 PHC2 NUP205 PTCD3	1.02e-04	989	66	9	36424410
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	TNPO1 DOCK2 KIFBP DDX46 ILK YLPM1 PSMD2	1.18e-04	582	66	7	20467437
Pubmed	Characterization of the human adenylyl cyclase gene family: cDNA, gene structure, and tissue distribution of the nine isoforms.	ADCY3 ADCY5	1.27e-04	9	66	2	12503609
Pubmed	Role of the calcium modulated cyclases in the development of the retinal projections.	ADCY3 ADCY5	1.27e-04	9	66	2	17229090
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	TNPO1 JUP URB1 DDX46 YLPM1 PSMD2 CUL7 HEATR5B NUP205	1.32e-04	1024	66	9	24711643
Pubmed	BCAR1 promotes proliferation and cell growth in lung adenocarcinoma via upregulation of POLR2A.	DOCK2 TLK2 MTOR AP1G2 PHC2 CASK	1.46e-04	419	66	6	33001583
Pubmed	Large-scale mapping of human protein-protein interactions by mass spectrometry.	TLK2 KIFBP JUP ILK CLK2 PSMD2 PYGM HERC1 NUP205 PTCD3	1.46e-04	1284	66	10	17353931
Pubmed	SARS-CoV-2 uses Spike glycoprotein to control the host's anaerobic metabolism by inhibiting LDHB.	TNPO1 JUP DDX46 HDHD5 PSMD2 NUP205 PTCD3	1.52e-04	607	66	7	39147351
Pubmed	Purification and characterization of a soluble form of mammalian adenylyl cyclase.	ADCY3 ADCY5	1.58e-04	10	66	2	8663304
Pubmed	Comprehensive analysis of the expression patterns of the adenylate cyclase gene family in the developing and adult mouse brain.	ADCY3 ADCY5	1.58e-04	10	66	2	16615126
Pubmed	Arrhythmogenic Right Ventricular Cardiomyopathy Overview	JUP RYR2	1.58e-04	10	66	2	20301310
Pubmed	Mechanism of human immunodeficiency virus-induced complement expression in astrocytes and neurons.	ADCY3 ADCY5	1.58e-04	10	66	2	11884542
Pubmed	Hippo/Mst signalling couples metabolic state and immune function of CD8α+ dendritic cells.	LATS2 MTOR	1.93e-04	11	66	2	29849151
Pubmed	Involvement of adenylate cyclase and p70(S6)-kinase activation in IL-10 up-regulation in human monocytes by gp41 envelope protein of human immunodeficiency virus type 1.	ADCY3 ADCY5	1.93e-04	11	66	2	10089566
Pubmed	Cardiac disease and arrhythmogenesis: Mechanistic insights from mouse models.	JUP RYR2	1.93e-04	11	66	2	27766308
Pubmed	gp120- and TNF-alpha-induced modulation of human B cell function: proliferation, cyclic AMP generation, Ig production, and B-cell receptor expression.	ADCY3 ADCY5	1.93e-04	11	66	2	10808179
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	TNPO1 DDX46 YLPM1 PAN2 PHC2 CASK NUP205 PTCD3 SYNGAP1	1.99e-04	1082	66	9	38697112
Pubmed	Cold-inducible RBM3 inhibits PERK phosphorylation through cooperation with NF90 to protect cells from endoplasmic reticulum stress.	JUP AP1G2 DDX60L	2.07e-04	60	66	3	26472337
Pubmed	Functional kinomics establishes a critical node of volume-sensitive cation-Cl- cotransporter regulation in the mammalian brain.	TLK2 MTOR	2.31e-04	12	66	2	27782176
Pubmed	HIV-1 envelope protein gp41 modulates expression of interleukin-10 and chemokine receptors on monocytes, astrocytes and neurones.	ADCY3 ADCY5	2.31e-04	12	66	2	10807185
Pubmed	The Arf family GTPase Arl4A complexes with ELMO proteins to promote actin cytoskeleton remodeling and reveals a versatile Ras-binding domain in the ELMO proteins family.	DOCK2 DOCK3	2.73e-04	13	66	2	21930703
Pubmed	Isoforms of mammalian adenylyl cyclase: multiplicities of signaling.	ADCY3 ADCY5	3.18e-04	14	66	2	14993377
Pubmed	Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity.	DOCK2 DOCK3	3.18e-04	14	66	2	12432077
Pubmed	mTORC2 interactome and localization determine aggressiveness of high-grade glioma cells through association with gelsolin.	JUP ILK MTOR PSMD2 NUP205	3.21e-04	312	66	5	37120454
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	TNPO1 KIFBP JUP URB1 GTF3C2 MTOR PSMD2 KIF3C NUP205 PTCD3	3.37e-04	1425	66	10	30948266
Pubmed	Human transcription factor protein interaction networks.	JUP KMT2B GTF3C2 YLPM1 MRPL13 PSMD2 CUL7 HERC1 NUP205 PTCD3	3.45e-04	1429	66	10	35140242
Pubmed	Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.	TLK2 KLHL2 TPCN2 ILK TEDC2 AP1G2 ADCY3 CASK	3.57e-04	925	66	8	28986522
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	DDX46 GRID2IP OBSCN HERC1 MEI1 SYNGAP1	3.64e-04	497	66	6	36774506
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	TNPO1 KIFBP URB1 DDX46 MTOR HDHD5 PSMD2 DDX60L NUP205 PTCD3	3.66e-04	1440	66	10	30833792
Pubmed	An FAK-YAP-mTOR Signaling Axis Regulates Stem Cell-Based Tissue Renewal in Mice.	LATS2 MTOR	3.67e-04	15	66	2	28457749
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	TNPO1 KIFBP URB1 MTOR PSMD2 HEATR5B NUP205 RNF170	4.03e-04	942	66	8	31073040
Pubmed	Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.	TNPO1 DOCK3 URB1 KMT2B CUL7	4.09e-04	329	66	5	17474147
Pubmed	Characterization of the EGFR interactome reveals associated protein complex networks and intracellular receptor dynamics.	TNPO1 MTOR AP1G2 PSMD2	4.14e-04	183	66	4	23956138
Pubmed	Molecular characterization of the ankle-link complex in cochlear hair cells and its role in the hair bundle functioning.	ADCY3 ADCY5	4.18e-04	16	66	2	17567809
Pubmed	Hdac2 regulates the cardiac hypertrophic response by modulating Gsk3 beta activity.	ILK MTOR	4.74e-04	17	66	2	17322895
Pubmed	Association analysis of 3p21 with Crohn's disease in a New Zealand population.	DOCK3 IP6K1	4.74e-04	17	66	2	20307617
Pubmed	The C-terminal domain of TAP interacts with the nuclear pore complex and promotes export of specific CTE-bearing RNA substrates.	TNPO1 NUP205	4.74e-04	17	66	2	10668806
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	UBR2 TPCN2 LATS2 CLK2 TMPRSS6 TMC6 ZG16B OBSCN ADCY3 CASK	4.76e-04	1489	66	10	28611215
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	JUP FRY URB1 KMT2B OBSCN PKHD1 NUP205	4.87e-04	736	66	7	29676528
Pubmed	Integrin-linked kinase is an adaptor with essential functions during mouse development.	ILK MTOR	5.32e-04	18	66	2	19829382
Pubmed	FEZ1 dimerization and interaction with transcription regulatory proteins involves its coiled-coil region.	TLK2 TEDC2	5.32e-04	18	66	2	16484223
Pubmed	Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain.	DOCK2 IP6K1 NUP205	5.38e-04	83	66	3	9039502
Pubmed	Animal Models of Congenital Cardiomyopathies Associated With Mutations in Z-Line Proteins.	ILK OBSCN	5.94e-04	19	66	2	27171814
Pubmed	MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.	MTOR CLK2 YLPM1 MRPL13 CASK	6.00e-04	358	66	5	32460013
Pubmed	RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.	URB1 YLPM1 PKHD1 NUP205	6.01e-04	202	66	4	24639526
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	JUP RRN3 YLPM1 ZG16B PAN2 PSMD2 CASK NUP205	6.17e-04	1005	66	8	19615732
Pubmed	Follow-up examination of linkage and association to chromosome 1q43 in multiple sclerosis.	PSMD2 RYR2	6.59e-04	20	66	2	19626040
Pubmed	Ankmy2 Prevents Smoothened-Independent Hyperactivation of the Hedgehog Pathway via Cilia-Regulated Adenylyl Cyclase Signaling.	ADCY3 ADCY5	6.59e-04	20	66	2	32702291
Pubmed	Cytoplasmic Metadherin (MTDH) provides survival advantage under conditions of stress by acting as RNA-binding protein.	DOCK2 KMT2B OBSCN CUL7	7.45e-04	214	66	4	22199357
Pubmed	Requirement for the Mitochondrial Pyruvate Carrier in Mammalian Development Revealed by a Hypomorphic Allelic Series.	MTOR PDP2 PYGM	7.50e-04	93	66	3	27215380
Pubmed	Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity.	UBR2 HERC1 RNF170	7.98e-04	95	66	3	29643511
Pubmed	The long noncoding RNA Charme supervises cardiomyocyte maturation by controlling cell differentiation programs in the developing heart.	JUP CUL7	7.99e-04	22	66	2	36877136
Pubmed	Wnt regulation: exploring Axin-Disheveled interactions and defining mechanisms by which the SCF E3 ubiquitin ligase is recruited to the destruction complex.	TNPO1 JUP YLPM1 PSMD2 KIF3C CASK PTCD3	8.50e-04	809	66	7	32129710
Pubmed	Functional proteomics mapping of a human signaling pathway.	JUP KMT2B YLPM1 HERC1 RYR2 CASK	8.99e-04	591	66	6	15231748
Pubmed	Systematic identification of cancer cell vulnerabilities to natural killer cell-mediated immune surveillance.	DOCK2 DDX46 YLPM1 OBSCN	9.13e-04	226	66	4	31452512
Pubmed	The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis.	GTF3C2 HDHD5 PSMD2 PHC2 PTCD3	9.43e-04	396	66	5	26687479
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	JUP URB1 ILK GTF3C2 AP1G2 PSMD2 DDX60L NUP205 PTCD3	1.00e-03	1353	66	9	29467282
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	TNPO1 TLK2 JUP URB1 OBSCN PAN2 HERC1 ADCY3	1.01e-03	1084	66	8	11544199
Pubmed	SALM4 suppresses excitatory synapse development by cis-inhibiting trans-synaptic SALM3-LAR adhesion.	CASK SYNGAP1	1.03e-03	25	66	2	27480238
Pubmed	Loss of connectin novex-3 leads to heart dysfunction associated with impaired cardiomyocyte proliferation and abnormal nuclear mechanics.	OBSCN RYR2	1.03e-03	25	66	2	38877142
Pubmed	Tubby family proteins are adapters for ciliary trafficking of integral membrane proteins.	PKHD1 ADCY3	1.03e-03	25	66	2	28154160
Pubmed	Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	DOCK3 UBR2 KMT2B	1.04e-03	104	66	3	9205841
Pubmed	5-HT(6) receptor recruitment of mTOR as a mechanism for perturbed cognition in schizophrenia.	TNPO1 MTOR	1.21e-03	27	66	2	23027611
Pubmed	[The HIV nef and the Kaposi-sarcoma-associated virus K3/K5 proteins: "parasites"of the endocytosis pathway].	HLA-DPA1 AP1G2	1.21e-03	27	66	2	12836198
Pubmed	A protein interaction landscape of breast cancer.	UBR2 JUP ILK ZG16B CUL7 PTCD3	1.29e-03	634	66	6	34591612
Pubmed	Suppression of ACE2 SUMOylation protects against SARS-CoV-2 infection through TOLLIP-mediated selective autophagy.	TNPO1 JUP DDX46 YLPM1 ZG16B NUP205	1.36e-03	641	66	6	36057605
Pubmed	Neddylation modification of the U3 snoRNA-binding protein RRP9 by Smurf1 promotes tumorigenesis.	JUP PSMD2 PTCD3	1.45e-03	117	66	3	34662580
Pubmed	Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1.	TNPO1 DDX46 HDHD5 YLPM1 PSMD2 PTCD3	1.50e-03	653	66	6	33742100
Pubmed	Systematic analysis of human protein complexes identifies chromosome segregation proteins.	TLK2 KLHL2 URB1 DDX46 GTF3C2 YLPM1 PYGM PTCD3	1.51e-03	1155	66	8	20360068
Pubmed	The p97/VCP segregase is essential for arsenic-induced degradation of PML and PML-RARA.	DDX46 KMT2B PSMD2 NUP205	1.57e-03	262	66	4	36880596
Pubmed	Regulated endoplasmic reticulum-associated degradation of a polytopic protein: p97 recruits proteasomes to Insig-1 before extraction from membranes.	JUP PSMD2	1.70e-03	32	66	2	19815544
Pubmed	A phenotype survey of 36 mutant mouse strains with gene-targeted defects in glycosyltransferases or glycan-binding proteins.	B4GALNT2 GCNT1	1.80e-03	33	66	2	23118208
Pubmed	KCMF1 (potassium channel modulatory factor 1) Links RAD6 to UBR4 (ubiquitin N-recognin domain-containing E3 ligase 4) and lysosome-mediated degradation.	UBR2 PDP2	1.80e-03	33	66	2	25582440
Interaction	FEZ2 interactions	TLK2 TEDC2 MRPL13 KIF3C	1.03e-05	45	61	4	int:FEZ2
GeneFamily	Adenylate cyclases\|Deafness associated genes	ADCY3 ADCY5	2.57e-04	10	44	2	53
ToppCell	droplet-Kidney-KIDNEY-30m-Lymphocytic-Epcam____proximal_tube_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	URB1 HDHD5 TEDC2 YLPM1 PRSS36	3.49e-06	158	65	5	1d78578dc1f8ba43dacdccae1082c0b9d749f64d
ToppCell	COVID-19-Heart-CM_+_Macrophage\|Heart / Disease (COVID-19 only), tissue and cell type	DOCK2 DOCK3 OBSCN DDX60L RYR2	4.99e-06	170	65	5	4232fe937909f93d3736988c707b8f95ce993398
ToppCell	normal_Lung-T/NK_cells-Exhausted_Tfh\|T/NK_cells / Location, Cell class and cell subclass	DOCK3 TMPRSS6 ZG16B KIF3C RYR2	5.59e-06	174	65	5	e324320b52c904496e26fcecfa179b3431729ec0
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK3 PYGM ADCY3 ADCY5 RYR2	5.75e-06	175	65	5	316f2ea930437bf1243b1c0f45e6bd864112c6f2
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK3 PYGM ADCY3 ADCY5 RYR2	5.75e-06	175	65	5	a9f08e1e4c2997dcdd3e5d92daac480da19100b8
ToppCell	COVID-19-Heart-CM_3\|COVID-19 / Disease (COVID-19 only), tissue and cell type	DOCK3 FRY OBSCN DDX60L RYR2	5.91e-06	176	65	5	9df7a124ebafb0087da0cda133a394275d7bed81
ToppCell	COVID-19-Heart-CM_3\|Heart / Disease (COVID-19 only), tissue and cell type	DOCK3 FRY OBSCN DDX60L RYR2	6.96e-06	182	65	5	287fcc3897ae08841f6f85ae6c9cef16f75b1dd1
ToppCell	COVID-19-Heart-CM_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	DOCK3 FRY OBSCN ADCY5 RYR2	7.53e-06	185	65	5	549eeb521c3985bff396ea0f202db21822efa51f
ToppCell	CV-Healthy-3\|Healthy / Virus stimulation, Condition and Cluster	DOCK3 GCNT1 ADCY3 NUP205	7.60e-05	154	65	4	26bf81a86700db7e65c2384ffe94ed4253ea4047
ToppCell	CV-Healthy-3\|CV / Virus stimulation, Condition and Cluster	DOCK3 ADCY3 NUP205 SYNGAP1	9.02e-05	161	65	4	fd4a79385ea967b9900dc76a3add813b894a3a28
ToppCell	COVID-19-Heart-CM_+_Macrophage\|COVID-19 / Disease (COVID-19 only), tissue and cell type	DOCK3 FRY OBSCN RYR2	1.11e-04	170	65	4	3f15242a1d3e4e9871d9170b2ef05842fb609c29
ToppCell	E16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PAN2 LAMP5 GCNT1 CUL7	1.16e-04	172	65	4	8a6a2b4c6654bc976e60a02d0e7303a9071ed55f
ToppCell	normal_Lung-T/NK_cells-Exhausted_Tfh\|normal_Lung / Location, Cell class and cell subclass	DOCK3 TMPRSS6 KIF3C RYR2	1.19e-04	173	65	4	e8ead6c51c41dbd43c717ba9d1a7a0ab39c79330
ToppCell	droplet-Thymus-nan-21m-Lymphocytic-B_cell\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JUP KMT2B CUL7 MEI1	1.19e-04	173	65	4	0a0cd40bb5f61431fe34758626c8a63ec610a8a5
ToppCell	Adult-Mesenchymal-pericyte_cell-D175\|Adult / Lineage, Cell type, age group and donor	OBSCN ADCY3 ADCY5 RYR2	1.19e-04	173	65	4	fd6653d6be9ca6ac36798590694efe03cb758c67
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GRID2IP MTOR YLPM1 HERC1	1.22e-04	174	65	4	f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCell	COVID-19_Mild-Neu_3\|COVID-19_Mild / 5 Neutrophil clusters in COVID-19 patients	JUP RRN3 AP1G2 CASK	1.27e-04	176	65	4	2049767fd591045cfcf5b1071d80798e52843f27
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.3.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DOCK2 TMC6 DDX60L ADCY3	1.33e-04	178	65	4	0b398656f26c4061b11ccf98908d0e2e1367585a
ToppCell	human_hepatoblastoma-Tumor_cells-T6\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	DOCK2 DOCK3 FRY RYR2	1.36e-04	179	65	4	14fc8ccb6b215063d747643f47d780d2b237eb67
ToppCell	COVID-19-Heart-CM_+_EC_+_Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	DOCK3 FRY OBSCN RYR2	1.42e-04	181	65	4	719eb532453ab7cd7893726885bc75d74a10b21e
ToppCell	Adult-Mesenchymal-pericyte_cell-D122\|Adult / Lineage, Cell type, age group and donor	OBSCN ADCY3 ADCY5 RYR2	1.48e-04	183	65	4	fc31a43a637423cb3bb9aa184a3a889a0b9aaea6
ToppCell	COVID-19-Heart-CM_1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	DOCK3 OBSCN ADCY5 RYR2	1.51e-04	184	65	4	e737f0f14c49b07bbb04a165083ac32210bc5690
ToppCell	Children_(3_yrs)-Mesenchymal-pericyte_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	OBSCN ADCY3 ADCY5 RYR2	1.60e-04	187	65	4	86250acf088ec0c4800a0dfa031b0d4f7e52c342
ToppCell	Adult-Mesenchymal-pericyte_cell\|Adult / Lineage, Cell type, age group and donor	OBSCN ADCY3 ADCY5 RYR2	1.60e-04	187	65	4	62759efb660179402fb574ce5701c89a2e17bcfe
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FRY RAPGEF3 LAMP5 ADCY5	1.64e-04	188	65	4	874404a4fd9aa42873f6c53dc42da22d3b0fdb9e
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FRY RAPGEF3 LAMP5 ADCY5	1.64e-04	188	65	4	b21e93a70583c30d05c0833cd3d4d4bca44a039e
ToppCell	Children_(3_yrs)-Mesenchymal-pericyte_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	OBSCN ADCY3 ADCY5 RYR2	1.64e-04	188	65	4	ee151792c7ac9afe820f1a281c6dab383799f358
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FRY ADCY3 ADCY5 RYR2	1.67e-04	189	65	4	7fbe855bfdb47d35e040b04a80fe4b729a3764e8
ToppCell	RV-04._Ventricular_Cardiomyocyte_I\|RV / Chamber and Cluster_Paper	DOCK3 FRY OBSCN RYR2	1.67e-04	189	65	4	9c1debd65c13d63fd4f3158917d621b44b714c26
ToppCell	Mesenchymal-pericyte_cell\|World / Lineage, Cell type, age group and donor	OBSCN ADCY3 ADCY5 RYR2	1.67e-04	189	65	4	d7ed96add29f219183c802895fbff519b627f635
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FRY ADCY3 ADCY5 RYR2	1.67e-04	189	65	4	06b35abecd29f902cf251fcc1f6ad33db7ab08a2
ToppCell	COVID-19-Heart\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FRY OBSCN ADCY5 RYR2	1.71e-04	190	65	4	918ad5037881212008f9f69d5df5da91fd01422c
ToppCell	nucseq-Mesenchymal-Myocytic-Myocytic_1-Pericyte\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	OBSCN ADCY3 ADCY5 RYR2	1.71e-04	190	65	4	4eb92aef1ee868f4537483d19014d947b7684612
ToppCell	Fetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FRY ADCY3 ADCY5 RYR2	1.71e-04	190	65	4	d6b3a92119b210974a32af3fe9875d60eb02761e
ToppCell	nucseq-Mesenchymal-Myocytic-Myocytic_1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	OBSCN ADCY3 ADCY5 RYR2	1.71e-04	190	65	4	7be4341e2909101d756f14031c21e705eb45e69a
ToppCell	MS-Treg-exh_CD4\|MS / Condition, Cell_class and T cell subcluster	MRPL13 PYGM CASK SYNGAP1	1.78e-04	192	65	4	c6722bf142c84ccedd99c1a3344085aecb4cbab4
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FRY ADCY3 ADCY5 RYR2	1.78e-04	192	65	4	b54b0d5b88139905521c8d5d58332e89c08d589c
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FRY ADCY3 ADCY5 RYR2	1.78e-04	192	65	4	bfab13793e54de2550ee171397f7ece0625cdb4a
ToppCell	LV-04._Ventricular_Cardiomyocyte_I\|LV / Chamber and Cluster_Paper	DOCK3 FRY OBSCN RYR2	1.78e-04	192	65	4	ad19e2c1d36a0566c9b12ced10db78f4781c8ea6
ToppCell	COVID-19-Heart-CM_+_EC_+_Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	DOCK3 FRY OBSCN RYR2	1.81e-04	193	65	4	dd5378a1ef8eb0eda9a3aae62f3c2f3a1402bda0
ToppCell	COVID-19-lung-Pericytes/_Smooth_Muscle\|lung / Disease (COVID-19 only), tissue and cell type	FRY ADCY3 ADCY5 RYR2	1.85e-04	194	65	4	5e1e0513a54ec4cf0b247ec85c9fbc68dfac1da3
ToppCell	COVID-19-Heart-CM_1\|Heart / Disease (COVID-19 only), tissue and cell type	DOCK3 OBSCN ADCY5 RYR2	1.88e-04	195	65	4	f1ef50331eda8f1239dba6ea970df4eaccf032f1
ToppCell	PCW_10-12-Epithelial-Epithelial_airway-epi_intermediate_(1)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	DOCK3 FRY PKHD1 ERICH2	1.88e-04	195	65	4	d67a2b489c29bfd575751c13d2a5b1efdec5240a
ToppCell	COVID-19-Heart-CM_2\|Heart / Disease (COVID-19 only), tissue and cell type	DOCK3 FRY OBSCN RYR2	1.88e-04	195	65	4	75fc81bddb246dca3b437fb60827b1d4fe416405
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FRY LDOC1 ADCY3 RYR2	1.92e-04	196	65	4	ce6f7ddb8104471dc90347f427486379914d63b4
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-Pericytes\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FRY LDOC1 ADCY3 RYR2	1.92e-04	196	65	4	6d7179decea512dd49bb2d5f6a4f5989349d52a9
ToppCell	Parenchymal-NucSeq-Stromal-Pericyte\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	OBSCN ADCY3 ADCY5 RYR2	1.96e-04	197	65	4	41dd312f46a2b983c8d864adeb6970c0ca4a8048
ToppCell	Parenchymal-NucSeq-Stromal-Pericyte-Muscle_pericyte_pulmonary\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	OBSCN ADCY3 ADCY5 RYR2	1.96e-04	197	65	4	f66945f9007d59d4208849c7fd727f8519713fbc
ToppCell	Tracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_systemic_arterial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FRY ADCY3 ADCY5 RYR2	2.00e-04	198	65	4	7dd874b09c81cc512ccc1e9b65f290a5f94d736e
ToppCell	Biopsy_IPF-Epithelial-KRT5-/KRT17+\|Biopsy_IPF / Sample group, Lineage and Cell type	DOCK3 JUP PKHD1 KIF3C	2.08e-04	200	65	4	2fc7a3b3aea711ad3d96fd9513f4b40533056d86
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	TLK2 UBR2 JUP DDX60L	2.08e-04	200	65	4	12f1685ce8f218433068e090c9d839cd5a1910bf
Drug	AC1Q3G0K	DOCK3 KIFBP CYP2D7 ADCY3 ADCY5	7.26e-07	60	64	5	CID000002087
Drug	Gvapspat amide	B4GALNT2 PYGM RYR2	9.41e-06	15	64	3	CID000125015
Drug	racemic timolol	LATS2 CYP2D7 ADCY3 ADCY5	1.28e-05	51	64	4	CID000005478
Drug	SK&F 82958	ADCY3 ADCY5 RYR2	1.99e-05	19	64	3	ctd:C071262
Drug	Moxonidine [75438-57-2]; Down 200; 16.6uM; MCF7; HT_HG-U133A	KMT2B GTF3C2 MTOR ADCY3 RYR2 RNF170	2.03e-05	199	64	6	7343_DN
Drug	D-myo-inositol-1,4,5-triphosphate	TPCN2 RAPGEF3 MTOR B4GALNT2 PYGM IP6K1 ADCY3 ADCY5 RYR2	2.85e-05	568	64	9	CID000000806
Drug	alprenolol	LATS2 CYP2D7 ADCY3 ADCY5	3.18e-05	64	64	4	CID000002119
Disease	Malformations of Cortical Development	KIFBP MTOR	4.14e-04	14	64	2	C1955869
Disease	Cortical Dysplasia	KIFBP MTOR	4.14e-04	14	64	2	C0431380
Disease	autosomal recessive polycystic kidney disease (implicated_via_orthology)	MTOR PKHD1	5.45e-04	16	64	2	DOID:0110861 (implicated_via_orthology)
Disease	body mass index, type 2 diabetes mellitus	MTOR ADCY5	5.45e-04	16	64	2	EFO_0004340, MONDO_0005148
Disease	autosomal dominant intellectual developmental disorder (is_implicated_in)	TLK2 KMT2B	6.17e-04	17	64	2	DOID:0060307 (is_implicated_in)
Disease	body fat percentage	YLPM1 PKHD1 IP6K1 ERICH2 ADCY3 ADCY5	6.61e-04	488	64	6	EFO_0007800
Disease	Neurodevelopmental Disorders	ADCY5 CASK SYNGAP1	1.10e-03	93	64	3	C1535926
Disease	eosinophil percentage of leukocytes	DOCK3 UBR2 KIFBP KMT2B HLA-DPA1 PSMD2 NUP205	1.14e-03	746	64	7	EFO_0007991
Disease	aspartate aminotransferase measurement, serum alanine aminotransferase measurement, low density lipoprotein triglyceride measurement, body fat percentage, high density lipoprotein cholesterol measurement, sex hormone-binding globulin measurement	YLPM1 PKHD1 ERICH2 ADCY3 ADCY5	1.17e-03	364	64	5	EFO_0004612, EFO_0004696, EFO_0004735, EFO_0004736, EFO_0007800, EFO_0009946
Disease	creatinine measurement	FRY TPCN2 TMC6 OBSCN PKHD1 MRPL13 PSMD2 PHC2	1.35e-03	995	64	8	EFO_0004518
Disease	eosinophil percentage of granulocytes	DOCK3 UBR2 HLA-DPA1 PSMD2	1.69e-03	234	64	4	EFO_0007996
Disease	Epileptic encephalopathy	MTOR SYNGAP1	1.94e-03	30	64	2	C0543888
Disease	Severe Congenital Microcephaly	KIFBP CASK	2.07e-03	31	64	2	C3853041

Protein segments in the cluster

Peptide	Gene	Start	Entry
PLELMAEFLRAEMAR	ERICH2	66	A1L162
LRPHKLMIMLRSIRE	B4GALNT2	331	Q8NHY0
NREHLAMMERILGPI	CLK2	386	P49760
HMRAAILEKMPLVER	AP1G2	576	O75843
MRPEDRMFHIRAVIL	HLA-DPA1	1	P20036
LLLSVLPRHVAMEMK	ADCY5	431	O95622
RVHNLITDFLALMPM	NUP205	391	Q92621
LIFLIMTERSLHEPM	OR52Z1P	31	P0C646
LFHMPRKRMISLRFL	PAN2	1106	Q504Q3
DLVRRMLMLDPAERI	CASK	251	O14936
HTFRSDLREEILMLM	PTCD3	521	Q96EY7
MVDELVLLLHALLMR	LDOC1	1	O95751
LLIRMEVFPEHLARF	LATS2	756	Q9NRM7
TMLLPPLRERMELLH	HERC1	851	Q15751
MMKRIHSLLERYPEI	DDX60L	656	Q5H9U9
EQDPRALHMERLMRL	KIF3C	731	O14782
ALHMERLMRLDSFLE	KIF3C	736	O14782
ILLLVMDVRLHTPMY	OR2W5P	46	A6NFC9
VFKDPRVLDLLMHML	CUL7	156	Q14999
MALFRLVEPMAGRIL	ABCC11	1186	Q96J66
IDRLRVLLMLFHTMA	LAMP5	11	Q9UJQ1
TSLELPMAMRFRHLK	KMT2B	2556	Q9UMN6
ALHILARDPMNRMEI	JUP	566	P14923
SFLRPEILRLMTLFM	MEI1	1166	Q5TIA1
QMAELRILRLMPADA	OBSCN	2521	Q5VST9
MARHLLLPLVMLVIS	PRSS36	1	Q5K4E3
RLAAMLTLPEDLARM	PDP2	491	Q9P2J9
MELLMFILVRHMPHL	HEATR5B	1716	Q9P2D3
LMSMEPRRLEPAHLA	GRID2IP	921	A4D2P6
AVPIEDMQRIHLRFM	DOCK2	496	Q92608
DKYRHAREMMLLLPT	DOCK3	1771	Q8IZD9
MARGMAFLHTLEPLI	ILK	301	Q13418
RFREHDLPMVALEQM	ADCY3	806	O60266
MHRSEPFLKMSLLIL	EDDM13	1	A0A1B0GTR0
MRLKHLDMVLPEVAS	IP6K1	356	Q92551
LMALRLLSRLLAHMP	FRY	2061	Q5TBA9
FLLPMFRHIMDQRSL	DDX46	426	Q7L014
HKIEMLDRLLRAIYM	GCNT1	131	Q02742
DLFRIPMLRRMTFCL	SLC22A8	316	Q8TCC7
RPSMMQHLLRRLVFD	RYR2	2581	Q92736
MHKRRIAMLEPLTVD	KIFBP	446	Q96EK5
PRRIHMMSLGVLNLA	FADS6	261	Q8N9I5
RIMLRMAPDYDHLTL	MTOR	2266	P42345
MVHPVAERLDILMSL	RRN3	306	Q9NYV6
LLRLRMREELSAAPM	TEDC2	276	Q7L2K0
RFPEALRLALMLNDM	PSMD2	261	Q13200
RMAFPLLDMVDLERR	HDHD5	161	Q9BXW7
MERIMDLPTLLRHAF	RNF170	171	Q96K19
DLLPVGMHRILMLVR	PKHD1	986	P08F94
LLDRDRMMQTILHFP	URB1	1596	O60287
MMEELHSLDPRRQEL	TLK2	1	Q86UE8
MMLAQGLLLHFLPRD	ATG4D	151	Q86TL0
MIVAIFLLLVDLMHR	CYP2D7	11	A0A087X1C5
PEGTLLNMVLRRMHR	RAPGEF3	36	O95398
MHRPEAMLLLLTLAL	ZG16B	31	Q96DA0
QRDLELPDMHMRDLV	PHC2	766	Q8IXK0
AIPELMRILVDLERM	PYGM	346	P11217
LMLVEEELRRDHPAM	SYNGAP1	1266	Q96PV0
LEVRMDRLLPHMHNI	TNPO1	251	Q92973
LHRRTMMERLHLFPD	MRPL13	116	Q9BYD1
PRHMMRLDIRSLLQD	YLPM1	1991	P49750
FHDLLRREPMLRMQE	GTF3C2	806	Q8WUA4
LAVAQRDHMLRGMPL	TMC6	156	Q7Z403
DPNHFLMIMLSRFEL	UBR2	706	Q8IWV8
MLNMLIVFRFLRIIP	TPCN2	546	Q8NHX9
MLLLFHSKRMPVAEA	TMPRSS6	1	Q8IU80
EFMARLMEHVRLPLL	KLHL2	236	O95198