Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncalcium channel activity

PKD2L1 CATSPER1 PKD2L2 RYR3 PKD2

7.50e-07129275GO:0005262
GeneOntologyMolecularFunctioncalcium ion transmembrane transporter activity

PKD2L1 CATSPER1 PKD2L2 RYR3 PKD2

1.63e-06151275GO:0015085
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

PKD2L1 CATSPER1 CTNS PKD2L2 ATP1A4 RYR3 PKD2 GABRA6

4.86e-06758278GO:0015318
GeneOntologyMolecularFunctionligand-gated monoatomic ion channel activity

PKD2L1 CATSPER1 RYR3 PKD2 GABRA6

5.44e-06193275GO:0015276
GeneOntologyMolecularFunctionligand-gated channel activity

PKD2L1 CATSPER1 RYR3 PKD2 GABRA6

6.01e-06197275GO:0022834
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

PKD2L1 CATSPER1 CTNS PKD2L2 ATP1A4 RYR3 PKD2 GABRA6

6.77e-06793278GO:0015075
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

PKD2L1 CATSPER1 CTNS PKD2L2 ATP1A4 RYR3 PKD2

1.49e-05627277GO:0022890
GeneOntologyMolecularFunctiontransmembrane transporter activity

PKD2L1 CATSPER1 CTNS PKD2L2 ATP1A4 ABCA9 RYR3 PKD2 GABRA6

1.51e-051180279GO:0022857
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

PKD2L1 CATSPER1 CTNS PKD2L2 ATP1A4 RYR3 PKD2

2.16e-05664277GO:0008324
GeneOntologyMolecularFunctioncalcium-induced calcium release activity

RYR3 PKD2

2.63e-056272GO:0048763
GeneOntologyMolecularFunctionmonoatomic ion channel activity

PKD2L1 CATSPER1 PKD2L2 RYR3 PKD2 GABRA6

2.80e-05459276GO:0005216
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

PKD2L1 CATSPER1 PKD2L2 ATP1A4 RYR3 PKD2

3.02e-05465276GO:0046873
GeneOntologyMolecularFunctiontransporter activity

PKD2L1 CATSPER1 CTNS PKD2L2 ATP1A4 ABCA9 RYR3 PKD2 GABRA6

3.07e-051289279GO:0005215
GeneOntologyMolecularFunctionligand-gated monoatomic cation channel activity

PKD2L1 CATSPER1 RYR3 PKD2

3.58e-05140274GO:0099094
GeneOntologyMolecularFunctionchannel activity

PKD2L1 CATSPER1 PKD2L2 RYR3 PKD2 GABRA6

5.94e-05525276GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

PKD2L1 CATSPER1 PKD2L2 RYR3 PKD2 GABRA6

6.00e-05526276GO:0022803
GeneOntologyMolecularFunctiongated channel activity

PKD2L1 CATSPER1 RYR3 PKD2 GABRA6

7.58e-05334275GO:0022836
GeneOntologyMolecularFunctionmonoatomic cation channel activity

PKD2L1 CATSPER1 PKD2L2 RYR3 PKD2

8.59e-05343275GO:0005261
GeneOntologyMolecularFunctionmuscle alpha-actinin binding

PKD2L1 PKD2

1.83e-0415272GO:0051371
GeneOntologyMolecularFunctionintracellularly gated calcium channel activity

RYR3 PKD2

2.66e-0418272GO:0015278
GeneOntologyMolecularFunctioncalcium ion binding

PKD2L1 PKD2L2 MEGF8 CEMIP2 RYR3 PKD2

4.11e-04749276GO:0005509
GeneOntologyMolecularFunctioncalcium-activated cation channel activity

PKD2L1 CATSPER1

6.05e-0427272GO:0005227
GeneOntologyMolecularFunctionodorant binding

OR5D16 OR8B12 OR5D18

6.57e-04127273GO:0005549
GeneOntologyMolecularFunctionalpha-actinin binding

PKD2L1 PKD2

7.99e-0431272GO:0051393
GeneOntologyMolecularFunctionmonoatomic ion-gated channel activity

PKD2L1 CATSPER1

7.99e-0431272GO:0022839
GeneOntologyMolecularFunctionligand-gated calcium channel activity

RYR3 PKD2

7.99e-0431272GO:0099604
GeneOntologyMolecularFunctionintracellularly ligand-gated monoatomic ion channel activity

RYR3 PKD2

9.06e-0433272GO:0005217
GeneOntologyMolecularFunctionpotassium ion transmembrane transporter activity

PKD2L1 ATP1A4 PKD2

1.45e-03167273GO:0015079
GeneOntologyMolecularFunctionactinin binding

PKD2L1 PKD2

1.54e-0343272GO:0042805
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

PKD2L1 ATP1A4 PKD2

1.55e-03171273GO:0015081
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity

CATSPER1 PKD2

1.76e-0346272GO:0005245
GeneOntologyMolecularFunctionsodium channel activity

PKD2L1 PKD2

2.24e-0352272GO:0005272
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

OR5D16 PKD2L1 P2RY14 OR8B12 OR5D18 GABRA6

8.25e-031353276GO:0004888
GeneOntologyMolecularFunctionhydrolase activity, hydrolyzing O-glycosyl compounds

MAN2A1 CEMIP2

8.50e-03103272GO:0004553
GeneOntologyMolecularFunctionATPase-coupled transmembrane transporter activity

ATP1A4 ABCA9

9.48e-03109272GO:0042626
GeneOntologyMolecularFunctionpotassium channel activity

PKD2L1 PKD2

1.29e-02128272GO:0005267
GeneOntologyMolecularFunctionhydrolase activity, acting on glycosyl bonds

MAN2A1 CEMIP2

1.61e-02144272GO:0016798
GeneOntologyMolecularFunctionvoltage-gated monoatomic cation channel activity

CATSPER1 PKD2

1.78e-02152272GO:0022843
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

PKD2L1 CATSPER1 CTNS PKD2L2 ATP1A4 DHRS7C RYR3 PKD2 GABRA6

2.43e-061017269GO:0098660
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

PKD2L1 CATSPER1 CTNS PKD2L2 ATP1A4 DHRS7C RYR3 PKD2 GABRA6

5.17e-061115269GO:0034220
GeneOntologyBiologicalProcesscalcium ion transmembrane transport

PKD2L1 CATSPER1 PKD2L2 DHRS7C RYR3 PKD2

7.57e-06392266GO:0070588
GeneOntologyBiologicalProcessinorganic cation transmembrane transport

PKD2L1 CATSPER1 CTNS PKD2L2 ATP1A4 DHRS7C RYR3 PKD2

1.18e-05922268GO:0098662
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

PKD2L1 CATSPER1 CTNS PKD2L2 ATP1A4 DHRS7C RYR3 PKD2

1.38e-05942268GO:0098655
GeneOntologyBiologicalProcessmonoatomic ion transport

PKD2L1 CATSPER1 CTNS PKD2L2 ATP1A4 DHRS7C RYR3 PKD2 GABRA6

2.79e-051374269GO:0006811
GeneOntologyBiologicalProcesscalcium ion transport

PKD2L1 CATSPER1 PKD2L2 DHRS7C RYR3 PKD2

3.32e-05509266GO:0006816
GeneOntologyBiologicalProcessmonoatomic cation transport

PKD2L1 CATSPER1 CTNS PKD2L2 ATP1A4 DHRS7C RYR3 PKD2

6.03e-051157268GO:0006812
GeneOntologyBiologicalProcessdetection of mechanical stimulus

PKD2L1 PKD2L2 PKD2

1.13e-0475263GO:0050982
GeneOntologyBiologicalProcessprotein homotetramerization

PKD2L1 RYR3 PKD2

1.22e-0477263GO:0051289
GeneOntologyBiologicalProcessresponse to water

PKD2L1 PKD2

1.38e-0414262GO:0009415
GeneOntologyBiologicalProcessmetal ion transport

PKD2L1 CATSPER1 PKD2L2 ATP1A4 DHRS7C RYR3 PKD2

1.80e-041000267GO:0030001
GeneOntologyBiologicalProcessdetection of stimulus

OR5D16 PKD2L1 OR8B12 PKD2L2 OR5D18 PKD2

2.28e-04722266GO:0051606
GeneOntologyBiologicalProcessprotein tetramerization

PKD2L1 RYR3 PKD2

3.80e-04113263GO:0051262
GeneOntologyBiologicalProcesschemical homeostasis

CTNS ATP1A4 DHRS7C RYR3 TMEM199 HECTD4 PKD2

6.97e-041249267GO:0048878
GeneOntologyBiologicalProcessrelease of sequestered calcium ion into cytosol

DHRS7C RYR3 PKD2

8.02e-04146263GO:0051209
GeneOntologyBiologicalProcessnegative regulation of sequestering of calcium ion

DHRS7C RYR3 PKD2

8.18e-04147263GO:0051283
GeneOntologyBiologicalProcessregulation of sequestering of calcium ion

DHRS7C RYR3 PKD2

8.50e-04149263GO:0051282
GeneOntologyBiologicalProcessintracellular monoatomic cation homeostasis

ATP1A4 DHRS7C RYR3 TMEM199 PKD2

8.81e-04611265GO:0030003
GeneOntologyBiologicalProcesssequestering of calcium ion

DHRS7C RYR3 PKD2

9.18e-04153263GO:0051208
GeneOntologyBiologicalProcessintracellular monoatomic ion homeostasis

ATP1A4 DHRS7C RYR3 TMEM199 PKD2

9.54e-04622265GO:0006873
GeneOntologyBiologicalProcessinorganic ion homeostasis

ATP1A4 DHRS7C RYR3 TMEM199 PKD2

9.54e-04622265GO:0098771
GeneOntologyBiologicalProcessrelease of sequestered calcium ion into cytosol by sarcoplasmic reticulum

DHRS7C RYR3

9.90e-0437262GO:0014808
GeneOntologyBiologicalProcessrelease of sequestered calcium ion into cytosol by endoplasmic reticulum

DHRS7C RYR3

1.10e-0339262GO:1903514
GeneOntologyBiologicalProcessdetection of external stimulus

PKD2L1 PKD2L2 PKD2

1.31e-03173263GO:0009581
GeneOntologyBiologicalProcessdetection of abiotic stimulus

PKD2L1 PKD2L2 PKD2

1.35e-03175263GO:0009582
GeneOntologyBiologicalProcesssarcoplasmic reticulum calcium ion transport

DHRS7C RYR3

1.40e-0344262GO:0070296
GeneOntologyBiologicalProcessmonoatomic cation homeostasis

ATP1A4 DHRS7C RYR3 TMEM199 PKD2

1.67e-03705265GO:0055080
GeneOntologyBiologicalProcessmonoatomic ion homeostasis

ATP1A4 DHRS7C RYR3 TMEM199 PKD2

1.79e-03717265GO:0050801
GeneOntologyBiologicalProcesssodium ion transmembrane transport

PKD2L1 ATP1A4 PKD2

2.21e-03208263GO:0035725
GeneOntologyBiologicalProcesscalcium ion transmembrane import into cytosol

DHRS7C RYR3 PKD2

2.50e-03217263GO:0097553
GeneOntologyCellularComponenttransmembrane transporter complex

PKD2L1 CATSPER1 ATP1A4 RYR3 TMEM199 PKD2 GABRA6

4.42e-06523287GO:1902495
GeneOntologyCellularComponenttransporter complex

PKD2L1 CATSPER1 ATP1A4 RYR3 TMEM199 PKD2 GABRA6

6.15e-06550287GO:1990351
GeneOntologyCellularComponentcalcium channel complex

PKD2L1 CATSPER1 RYR3

1.26e-0473283GO:0034704
GeneOntologyCellularComponentmonoatomic ion channel complex

PKD2L1 CATSPER1 RYR3 PKD2 GABRA6

1.31e-04378285GO:0034702
GeneOntologyCellularComponentendoplasmic reticulum membrane

PEDS1 OR5D18 DNAJC25 MACO1 DHRS7C RYR3 TMEM199 PKD2

2.14e-041293288GO:0005789
GeneOntologyCellularComponentendoplasmic reticulum subcompartment

PEDS1 OR5D18 DNAJC25 MACO1 DHRS7C RYR3 TMEM199 PKD2

2.21e-041299288GO:0098827
GeneOntologyCellularComponentnuclear outer membrane-endoplasmic reticulum membrane network

PEDS1 OR5D18 DNAJC25 MACO1 DHRS7C RYR3 TMEM199 PKD2

2.55e-041327288GO:0042175
GeneOntologyCellularComponentcation channel complex

PKD2L1 CATSPER1 RYR3 PKD2

2.58e-04235284GO:0034703
GeneOntologyCellularComponentsarcoplasmic reticulum membrane

DHRS7C RYR3

1.65e-0345282GO:0033017
GeneOntologyCellularComponentcation-transporting ATPase complex

ATP1A4 TMEM199

1.96e-0349282GO:0090533
GeneOntologyCellularComponentnon-motile cilium

PKD2L1 ATP1A4 PKD2

2.24e-03196283GO:0097730
GeneOntologyCellularComponentATPase dependent transmembrane transport complex

ATP1A4 TMEM199

2.46e-0355282GO:0098533
GeneOntologyCellularComponentmembrane protein complex

PKD2L1 CATSPER1 ATP1A4 RYR3 TMEM199 PKD2 GABRA6

2.97e-031498287GO:0098796
DomainPKD_2

PKD2L1 PKD2L2 PKD2

2.11e-085253IPR003915
DomainPKD1_2_channel

PKD2L1 PKD2L2 PKD2

3.47e-0711253IPR013122
DomainPKD_channel

PKD2L1 PKD2L2 PKD2

3.47e-0711253PF08016
DomainPC1

PKD2L1 PKD2L2

1.03e-054252IPR000434
DomainChannel_four-helix_dom

CATSPER1 PKD2

2.62e-0357252IPR027359
Domain-

CATSPER1 PKD2

2.62e-03572521.20.120.350
DomainEF_hand_dom

PKD2L1 RYR3 PKD2

3.56e-03232253IPR002048
Domain-

PKD2L1 RYR3 PKD2

4.94e-032612531.10.238.10
DomainEF-hand-dom_pair

PKD2L1 RYR3 PKD2

6.43e-03287253IPR011992
DomainIon_trans_dom

CATSPER1 RYR3

1.01e-02114252IPR005821
DomainIon_trans

CATSPER1 RYR3

1.01e-02114252PF00520
DomainGPCR_Rhodpsn_7TM

OR5D16 P2RY14 OR8B12 OR5D18

1.14e-02670254IPR017452
Domain7tm_1

OR5D16 P2RY14 OR8B12 OR5D18

1.18e-02677254PF00001
DomainG_PROTEIN_RECEP_F1_1

OR5D16 P2RY14 OR8B12 OR5D18

1.23e-02685254PS00237
DomainG_PROTEIN_RECEP_F1_2

OR5D16 P2RY14 OR8B12 OR5D18

1.27e-02691254PS50262
DomainGPCR_Rhodpsn

OR5D16 P2RY14 OR8B12 OR5D18

1.27e-02692254IPR000276
DomainOlfact_rcpt

OR5D16 OR8B12 OR5D18

1.51e-02393253IPR000725
Pubmed

Polycystin-2 expression and function in adult mouse lacrimal acinar cells.

PKD2L1 PKD2L2 PKD2

4.67e-10328321508103
Pubmed

Polycystin channels and kidney disease.

PKD2L1 PKD2L2 PKD2

4.67e-09528311698076
Pubmed

Two members of the TRPP family of ion channels, Pkd1l3 and Pkd2l1, are co-expressed in a subset of taste receptor cells.

PKD2L1 PKD2L2 PKD2

5.59e-081028316805797
Pubmed

The calcium-binding EF-hand in polycystin-L is not a domain for channel activation and ensuing inactivation.

PKD2L1 PKD2L2

6.25e-07228211959145
Pubmed

Identification of the structural motif responsible for trimeric assembly of the C-terminal regulatory domains of polycystin channels PKD2L1 and PKD2.

PKD2L1 PKD2

6.25e-07228220408813
Pubmed

Hydrophobic pore gates regulate ion permeation in polycystic kidney disease 2 and 2L1 channels.

PKD2L1 PKD2

6.25e-07228229899465
Pubmed

An introduction to TRP channels.

PKD2L1 PKD2L2 PKD2

1.35e-062728316460286
Pubmed

Polycystin-2 interacts with troponin I, an angiogenesis inhibitor.

PKD2L1 PKD2

1.87e-06328212525172
Pubmed

Genes homologous to the autosomal dominant polycystic kidney disease genes (PKD1 and PKD2).

PKD2L1 PKD2L2

1.87e-06328210602361
Pubmed

A quantitative analysis of the spatiotemporal pattern of transient receptor potential gene expression in the developing mouse cochlea.

PKD2L1 PKD2L2 PKD2

2.51e-063328319834762
Pubmed

Specific association of the gene product of PKD2 with the TRPC1 channel.

PKD2L1 PKD2

3.75e-06428210097141
Pubmed

Developmental waves of mechanosensitivity acquisition in sensory neuron subtypes during embryonic development.

PKD2L1 PKD2L2 PKD2

6.05e-064428319322198
Pubmed

Troponin I binds polycystin-L and inhibits its calcium-induced channel activation.

PKD2L1 PKD2

6.24e-06528212809519
Pubmed

Proteomics characterization of abundant Golgi membrane proteins.

SCAMP3 MAN2A1

1.06e-041928211042173
Pubmed

Systematic identification of pathological lamin A interactors.

NINJ2 ABCA9 TMEM199 PKD2

1.48e-0433728424623722
Pubmed

Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.

SCAMP3 MAN2A1 MACO1 CEMIP2 TMEM199 SLC35F5

1.68e-04106128633845483
Pubmed

The interactome of metabolic enzyme carbonic anhydrase IX reveals novel roles in tumor cell migration and invadopodia/MMP14-mediated invasion.

MACO1 CEMIP2 TMEM199

3.80e-0417628328692057
Pubmed

Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations.

HECTD4 PKD2

4.09e-043728222797727
Pubmed

Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins.

SCAMP3 TMEM181 SLC35F5 PKD2

6.52e-0449928422810586
Pubmed

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.

SCAMP3 MEGF8 MACO1 CEMIP2

6.77e-0450428434432599
Pubmed

DEFOG: a practical scheme for deciphering families of genes.

OR5D16 OR8B12 OR5D18

7.18e-0421928312213199
InteractionGJA1 interactions

NINJ2 SCAMP3 DNAJC25 MACO1 CEMIP2 TMEM199

6.33e-05583256int:GJA1
InteractionPKD2L2 interactions

PKD2L2 PKD2

8.07e-0511252int:PKD2L2
InteractionREEP4 interactions

NINJ2 SERF1A DNAJC25 TMEM199

8.81e-05193254int:REEP4
Cytoband11q11

OR5D16 OR5D18

3.81e-044728211q11
GeneFamilyTransient receptor potential cation channels

PKD2L1 PKD2L2 PKD2

2.67e-0628183249
GeneFamilyOlfactory receptors, family 5

OR5D16 OR5D18

5.45e-03112182152
GeneFamilyEF-hand domain containing

RYR3 PKD2

1.97e-02219182863
CoexpressionGSE11864_UNTREATED_VS_CSF1_IFNG_PAM3CYS_IN_MAC_DN

SCAMP3 SERF1A MACO1 SLC35F5

4.23e-05199264M3132
CoexpressionGSE16385_MONOCYTE_VS_12H_IFNG_TNF_TREATED_MACROPHAGE_DN

P2RY14 MAN2A1 SERF1A TMEM181

4.31e-05200264M7920
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(CH25H+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PKD2L1 P2RY14 PKD2L2

1.03e-04146283669001b772b6d6109a09727619ed5829122b48db
ToppCellChildren_(3_yrs)-Immune-mast_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

P2RY14 CATSPER1 RYR3

1.19e-04153283d3fb83ca984c7583b1e51c364be6c7c17f67b048
ToppCellNS-moderate-d_07-13-Myeloid-Mast_cell|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

P2RY14 CATSPER1 ATP1A4

1.26e-0415628317c38d3b03fc38cb125cf0d165b2fd694cd88edd
ToppCellCD8+_Memory_T_cell-RSV-1|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

MEGF8 DNAJC25 CEMIP2

1.38e-04161283f6d04f67da3557e80f13ef27bfabb94dcd80db2f
ToppCellNS-moderate-d_16-33-Myeloid-Mast_cell|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

P2RY14 CATSPER1 ATP1A4

1.46e-0416428335c673380f75cb4bfe080089bc723c4373bcc7a5
ToppCellfacs-Marrow-B-cells-24m-Hematologic-Unknown_Progenitor|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PKD2L1 PKD2L2 TMEM181

1.68e-0417228365b8935a972bf00b7a10dc2d442128fc0ed78bcb
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-Mast-Mast-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

P2RY14 CATSPER1 ATP1A4

1.71e-041732833a39c7f290a9914fcf747e6bc6f13a509413b33c
ToppCellmoderate-Myeloid-Mast_cell|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

P2RY14 CATSPER1 ATP1A4

1.76e-04175283bbd2971bc6d69e507f90a637834d0936c205c590
ToppCellCV-Severe-7|CV / Virus stimulation, Condition and Cluster

P2RY14 MAN2A1 CEMIP2

1.79e-041762833de0c7d77210049e5616db21eed1490a17a5ec2d
ToppCellCV-Severe-7|Severe / Virus stimulation, Condition and Cluster

P2RY14 MAN2A1 CEMIP2

1.82e-0417728382fdd6185b368f54f03de389427cbe3071d21a99
ToppCelldroplet-Lung-LUNG-1m-Lymphocytic-Plasma_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NINJ2 PKD2L2 SERF1A

1.82e-04177283ff97398d2adb83063b7c53a264bfae86ea7ea304
ToppCelldroplet-Lung-LUNG-1m-Lymphocytic-plasma_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NINJ2 PKD2L2 SERF1A

1.82e-04177283c6812679aa6522d03bd29144e71c5fae6a92325e
ToppCellPSB-critical-LOC-Myeloid-Basophil|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

P2RY14 CATSPER1 ATP1A4

1.85e-0417828345bdbb96094c97756e1b6eebd80eadd8472143f2
ToppCell5'-Adult-LargeIntestine-Hematopoietic-Myeloid-Mast_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

P2RY14 CATSPER1 ATP1A4

1.92e-041802832658a6be43d6d94767b4fc5af2d8632469a8a979
ToppCellTransplant_Alveoli_and_parenchyma-Immune-Mast_cells|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

P2RY14 CATSPER1 ATP1A4

2.08e-04185283a6e5328801c233a44153420e2cdae644b253f540
ToppCellLPS_only-Hematopoietic_Meg-Ery-Erythroid|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CATSPER1 MACO1 HECTD4

2.11e-04186283affc246a1091e44dc85a5e237c778a7541d5a2b4
ToppCell5'-Parenchyma_lung-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-Mast_cells_L.1.4.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

P2RY14 CATSPER1 ATP1A4

2.11e-04186283f690e26b2ed024bd8ede494b8e9a00976fdc9734
ToppCellLPS_only-Hematopoietic_Meg-Ery|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CATSPER1 MACO1 HECTD4

2.11e-0418628340d1e15402fdfb3b5ae850a2070cd4b68fda3159
ToppCellLPS_only-Hematopoietic_Meg-Ery-Erythroid-Erythroid|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CATSPER1 MACO1 HECTD4

2.11e-04186283e5014443e9d6e25943308483e20d48b776ae5373
ToppCell5'-Parenchyma_lung-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

P2RY14 CATSPER1 ATP1A4

2.14e-04187283bdcef4f3e093c3646b639a189bbe93d6f4c40f3c
ToppCell5'-Parenchyma_lung-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

P2RY14 CATSPER1 ATP1A4

2.14e-0418728309348f1e8bbbca8dca885461937b9b1dd248b034
ToppCelltumor_Lymph_Node_/_Brain-Myeloid_cells-Undetermined|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

P2RY14 CATSPER1 ATP1A4

2.14e-0418728355d5b21517c89736592982af40fd4cd64be62a3c
ToppCell5'-Parenchyma_lung-Immune_Myeloid_mast|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

P2RY14 CATSPER1 ATP1A4

2.14e-041872830f7a42c55997e34a0d20e492e16b03e91e965335
ToppCell5'-Parenchyma_lung-Immune_Myeloid_mast-Myeloid_Mast/Baso|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

P2RY14 CATSPER1 ATP1A4

2.14e-04187283064730fa72f8637c3db3fc34d2e363d2b9a38f1d
ToppCellMast_cells|World / lung cells shred on cell class, cell subclass, sample id

P2RY14 CATSPER1 ATP1A4

2.18e-04188283229d24b87e945c4d543d11ac70761e45175ba0e5
ToppCelltumor_Lung-MAST_cells-MAST|tumor_Lung / Location, Cell class and cell subclass

P2RY14 CATSPER1 ATP1A4

2.21e-04189283cd977962e01756b663728dae32ab9aba15bf7e22
ToppCellnormal_Lung-MAST_cells-MAST|normal_Lung / Location, Cell class and cell subclass

P2RY14 CATSPER1 ATP1A4

2.21e-04189283fd053209034fca6eaefe0e5ad024ac4548a100c9
ToppCelltumor_Lung-MAST_cells|tumor_Lung / Location, Cell class and cell subclass

P2RY14 CATSPER1 ATP1A4

2.21e-04189283300670be76454f197bd04f82c533579dd3671969
ToppCellnormal_Lung-MAST_cells|normal_Lung / Location, Cell class and cell subclass

P2RY14 CATSPER1 ATP1A4

2.21e-04189283f09e387dc0626536050cd537dda212471a7267c4
ToppCellmetastatic_Brain-MAST_cells|metastatic_Brain / Location, Cell class and cell subclass

P2RY14 CATSPER1 ATP1A4

2.25e-04190283587bdf020ef222b5b76f0fae0cec3d44bcdac8e6
ToppCellmetastatic_Brain-MAST_cells-MAST|metastatic_Brain / Location, Cell class and cell subclass

P2RY14 CATSPER1 ATP1A4

2.25e-041902839dc8afb99de9e4d41f26a41cd8cf1fc0100a54f0
ToppCellcellseq-Immune-Hematopoietic-Granulocytic|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

P2RY14 CATSPER1 ATP1A4

2.32e-041922837af799b624167d1751c83e26b056be3692136c39
ToppCellcellseq-Immune-Hematopoietic|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

P2RY14 CATSPER1 ATP1A4

2.32e-04192283a081624e81e6fca8bb8da58fc2809af451c7315c
ToppCellcellseq-Immune-Hematopoietic-Granulocytic-Mast/Basophil|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

P2RY14 CATSPER1 ATP1A4

2.32e-04192283b29d6b4bed4d55060586276973732461538752df
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-Mast-Mast-A|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

P2RY14 CATSPER1 ATP1A4

2.39e-04194283b45e159340e11e453bb01ff425bd23bd846b18d8
ToppCell3'-Broncho-tracheal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-Mast_cells_L.1.4.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

P2RY14 CATSPER1 ATP1A4

2.39e-041942839d7f232ef5f27c28f325edfa6614f479013acbba
ToppCelldistal-Hematologic-Basophil/Mast_1-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

P2RY14 CATSPER1 ATP1A4

2.42e-041952835aab51a1e6842f2a397926e451133a67467fc614
ToppCell3'-Broncho-tracheal-Immune_Myeloid_mast|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

P2RY14 CATSPER1 ATP1A4

2.46e-0419628355e562be096a510f6414811238e633accd18570e
ToppCell3'-Broncho-tracheal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

P2RY14 CATSPER1 ATP1A4

2.46e-04196283102bced15ba1f2f9aafdcf07e64195b8e1b0d87c
ToppCell3'-Broncho-tracheal-Immune_Myeloid_mast-Myeloid_Mast/Baso|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

P2RY14 CATSPER1 ATP1A4

2.46e-0419628357fd7b39611e30a68429dea1801476b0d44c6dc1
ToppCell3'-Broncho-tracheal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

P2RY14 CATSPER1 ATP1A4

2.46e-041962834f007bff8ed7592c277d8397b054e1c799157912
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-Mast|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

P2RY14 CATSPER1 ATP1A4

2.46e-041962830ebf7e5a9281ec1f33dccd1f8895afd513591b91
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-Mast-Mast|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

P2RY14 CATSPER1 ATP1A4

2.46e-04196283bd482b7df2993d87c0997a40c4cbd34ba07910cb
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-Mast-Mast-Z|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

P2RY14 CATSPER1 ATP1A4

2.50e-041972837619924615a43011b4a86efbe6e7e5445f96722b
ToppCell10x5'v1-week_12-13-Myeloid_neutrophil-granulo-eo/baso/mast-mast_cell|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

P2RY14 ATP1A4 RYR3

2.50e-0419728361f909737c5f630beffdd326c6844215643dbdde
ToppCellBiopsy_Other_PF-Immune-Mast_cells|Biopsy_Other_PF / Sample group, Lineage and Cell type

P2RY14 CATSPER1 ATP1A4

2.54e-041982839f015553598d4c6774b2f9759e8c0f0f93e51c67
ToppCellBronchial-10x5prime-Immune_Myeloid-Mast_cell|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

P2RY14 CATSPER1 ATP1A4

2.61e-0420028396540be0e906bbc626049a41978be3dc051d2024
ToppCellParenchymal-10x5prime-Immune_Myeloid-Mast_cell-Mast_cell|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

P2RY14 CATSPER1 ATP1A4

2.61e-042002838943278190f42016ee914e584d1b6b9aeaf7c73f
ToppCellBiopsy_IPF-Immune-Mast_cells|Biopsy_IPF / Sample group, Lineage and Cell type

P2RY14 CATSPER1 ATP1A4

2.61e-0420028344d07a3fa768ccdcd2a0483a41483d5c11c9111e
ToppCellBronchial-10x5prime-Immune_Myeloid-Mast_cell-Mast_cell|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

P2RY14 CATSPER1 ATP1A4

2.61e-0420028341d7736427494cb30a2f23722ea2b86ff308cfd8
ToppCellTracheal-10x5prime-Immune_Myeloid-Mast_cell-Mast_cell|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

P2RY14 CATSPER1 ATP1A4

2.61e-042002831c58860932ed47263a5a537a64f0343201463c21
ToppCellTracheal-10x5prime-Immune_Myeloid-Mast_cell|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

P2RY14 CATSPER1 ATP1A4

2.61e-04200283c3511607692e05f44538a376253673dd18f77908
ToppCellParenchymal-10x5prime-Immune_Myeloid-Mast_cell|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

P2RY14 CATSPER1 ATP1A4

2.61e-04200283ea52df18400550b65de142d03b3b0963436e03d9
Druglanthanum

PKD2L1 CATSPER1 PKD2L2 RYR3 PKD2

5.13e-07136275CID000023926
DrugCNS 1145

CATSPER1 RYR3 PKD2

7.92e-0633273CID000190902
DrugIHC-64

CATSPER1 RYR3 PKD2

7.92e-0633273CID000162753
Drugnimodipine

CATSPER1 RYR3 PKD2 GABRA6

2.47e-05145274CID000004497
Drugprocaine

CATSPER1 RYR3 PKD2 GABRA6

3.05e-05153274CID000004914
Drugamiloride

PKD2L1 CATSPER1 PKD2L2 RYR3 PKD2

3.09e-05315275CID000016230
DrugCinildipine

CATSPER1 RYR3 PKD2

3.95e-0556273CID000002752
Druggabapentin

CATSPER1 RYR3 PKD2 GABRA6

4.50e-05169274CID000003446
Drugnilvadipine

CATSPER1 RYR3 PKD2

4.86e-0560273CID000004494
Drugriluzole

CATSPER1 RYR3 PKD2 GABRA6

5.04e-05174274CID000005070
DrugIAA-94

CATSPER1 RYR3 PKD2

5.11e-0561273CID000003667
Druglercanidipine

CATSPER1 RYR3 PKD2

5.63e-0563273CID000065866
Drugmibefradil

CATSPER1 RYR3 PKD2

5.90e-0564273CID000060662
Druggallopamil

CATSPER1 RYR3 PKD2

6.77e-0567273CID000001234
Drugbaclofen

CATSPER1 RYR3 PKD2 GABRA6

7.24e-05191274CID000002284
DrugAC1L2AC7

CATSPER1 RYR3 PKD2

7.40e-0569273CID000068733
Drugvalproate

CATSPER1 SERF1A RYR3 PKD2 GABRA6

7.62e-05381275CID000003121
Druggadolinium

CATSPER1 PKD2L2 RYR3 PKD2

8.49e-05199274CID000023982
DrugCAS 298-57-7

CATSPER1 RYR3 PKD2

8.75e-0573273CID000002761
Drugethosuximide

CATSPER1 RYR3 PKD2

9.11e-0574273CID000003291
Drugnisoldipine

CATSPER1 RYR3 PKD2

1.07e-0478273CID000004499
DrugN-cyclopentyl-N-cyclobutylformamide

CATSPER1 RYR3 PKD2

1.11e-0479273CID005287890
DrugAC1NUZ8M

CATSPER1 RYR3 PKD2

1.74e-0492273CID000073211
Drugmanidipine

CATSPER1 RYR3 PKD2

1.91e-0495273CID000004008
Drugisotetrandrine

CATSPER1 RYR3 PKD2

2.04e-0497273CID000005422
Drugnitrendipine

CATSPER1 RYR3 PKD2

2.10e-0498273CID000004507
Drugisradipine

CATSPER1 RYR3 PKD2

2.23e-04100273CID000003784
Drugloperamide

CATSPER1 RYR3 PKD2

2.57e-04105273CID000003954
DrugAC1L1CR9

MAN2A1 RYR3

2.80e-0421272CID000002023
Druglamotrigine

CATSPER1 RYR3 PKD2

3.45e-04116273CID000003878
DrugAC1NBU2S

CATSPER1 RYR3 PKD2

3.54e-04117273CID004473765
Drugbepridil

CATSPER1 RYR3 PKD2

4.39e-04126273CID000002351
Drugpimozide

CATSPER1 RYR3 PKD2

4.50e-04127273CID000016362
Drugpolyethylenimine

PKD2L1 RYR3 PKD2

4.60e-04128273CID000009033
Drugcaffeine

P2RY14 CATSPER1 PKD2L2 RYR3 PKD2

4.63e-04562275CID000002519
Drughalothane

CATSPER1 RYR3 PKD2 GABRA6

4.85e-04314274CID000003562
Drugcaged InsP3

RYR3 PKD2

5.39e-0429272CID000122248
Diseasepolycystic kidney disease 2 (implicated_via_orthology)

PKD2L1 PKD2L2 PKD2

6.83e-103273DOID:0110859 (implicated_via_orthology)
Diseaseautosomal dominant polycystic kidney disease (implicated_via_orthology)

PKD2L1 PKD2L2 PKD2

2.47e-0714273DOID:898 (implicated_via_orthology)
Diseaselysophosphatidylcholine 19:0 measurement

PKD2L1 GABRA6

8.05e-065272EFO_0021455
Diseasecups of coffee per day measurement

ATP1A4 HECTD4

6.16e-0440272EFO_0006782
Diseaseacute graft vs. host disease

PKD2L2 CEMIP2

1.12e-0354272EFO_0004599

Protein segments in the cluster

PeptideGeneStartEntry
SLAFETFIFFVVCLN

CATSPER1

446

Q8NEC5
VATDFFIFFCIISFS

ABCA9

221

Q8IUA7
VQFFFFCTFVVTELI

OR5D16

101

Q8NGK9
RTISFLGCVVQFFFF

OR5D18

91

Q8NGL1
LGCVVQFFFFCTFVV

OR5D18

96

Q8NGL1
QFFFFCTFVVTESFL

OR5D18

101

Q8NGL1
QFTVFGSAIFCVVIF

MAN2A1

6

Q16706
FSVFFVCVAFTSNII

MACO1

76

Q8N5G2
IDLFVFFSVFFSCFF

MEGF8

2646

Q7Z7M0
FVFCLIIFGTFTNQI

PEDS1

171

A5PLL7
FIAVCFAFVFSALIE

GABRA6

306

Q16445
RCILVVFQVVFKFFF

HECTD4

286

Q9Y4D8
FFFCFFVVSESFILS

OR8B12

101

Q8NGG6
VILVSVCAISVFQFF

DNAJC25

151

Q9H1X3
NTFICFAITSFSFFI

CEMIP2

81

Q9UHN6
FSIVFDVVFFIQHFC

CTNS

341

O60931
VRTFFPEFFFAVVAC

DHRS7C

286

A6NNS2
FFFIFFVQDVLFVLQ

SCAMP3

236

O14828
LVFFTVVINVFITAF

NINJ2

111

Q9NZG7
ISAFVFVVFFSVFFP

SERF1A

86

O75920
TATQVAKISFFFCFV

SLC35F5

236

Q8WV83
SVVETFIQQCQFFFY

ARHGAP5

1436

Q13017
SSRNIFSIVFVFFVC

P2RY14

231

Q15391
EFTCQTAFFVTIVVV

ATP1A4

921

Q13733
FNFIVTVVAAFVCTY

TMEM199

151

Q8N511
FRFFFVVLTFIVTCL

TMEM181

316

Q9P2C4
RIVFDITFFFFVIVI

RYR3

4746

Q15413
FIASCEITFCIFLFV

PKD2L2

281

Q9NZM6
EITFCIFLFVFTTQE

PKD2L2

286

Q9NZM6
VTTFDFFLAACEIIF

PKD2

466

Q13563
FSTFQECIFTQFRII

PKD2

626

Q13563
FSTFIKCIFTQFRII

PKD2L1

506

Q9P0L9