Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessneural crest cell development

SEMA3A LAMA5 SEMA4D DICER1

8.15e-0689304GO:0014032
GeneOntologyBiologicalProcessstem cell development

SEMA3A LAMA5 SEMA4D DICER1

1.35e-05101304GO:0048864
GeneOntologyBiologicalProcessneural crest cell differentiation

SEMA3A LAMA5 SEMA4D DICER1

1.51e-05104304GO:0014033
GeneOntologyBiologicalProcesstrunk neural crest cell migration

SEMA3A LAMA5

3.06e-056302GO:0036484
GeneOntologyBiologicalProcesstrunk segmentation

SEMA3A LAMA5

3.06e-056302GO:0035290
GeneOntologyBiologicalProcessneural crest cell migration

SEMA3A LAMA5 SEMA4D

9.91e-0562303GO:0001755
GeneOntologyBiologicalProcessmesenchymal cell migration

SEMA3A LAMA5 SEMA4D

1.09e-0464303GO:0090497
GeneOntologyBiologicalProcessganglion development

SEMA3A DICER1

3.08e-0418302GO:0061548
GeneOntologyCellularComponentsynapse-associated extracellular matrix

LAMA5 NCAN

1.64e-0413312GO:0099535
DomainIG

SNHG28 ALPK3 SEMA3A SEMA4D SIGLEC1 NCAN

6.98e-05421326SM00409
DomainIg_sub

SNHG28 ALPK3 SEMA3A SEMA4D SIGLEC1 NCAN

6.98e-05421326IPR003599
DomainEGF-like_CS

LAMA5 LTBP2 VWCE EPHA10 NCAN

7.58e-05261325IPR013032
DomainEGF_2

LAMA5 LTBP2 VWCE EPHA10 NCAN

8.15e-05265325PS01186
Domain-

SNHG28 ALPK3 SEMA3A SEMA4D SIGLEC1 EPHA10 NCAN

1.07e-046633272.60.40.10
DomainGrowth_fac_rcpt_

LAMA5 LTBP2 IGFBP4 VWCE

1.40e-04156324IPR009030
DomainIg-like_fold

SNHG28 ALPK3 SEMA3A SEMA4D SIGLEC1 EPHA10 NCAN

1.58e-04706327IPR013783
DomainIG_LIKE

SNHG28 ALPK3 SEMA3A SEMA4D SIGLEC1 NCAN

1.62e-04491326PS50835
DomainIg-like_dom

SNHG28 ALPK3 SEMA3A SEMA4D SIGLEC1 NCAN

1.85e-04503326IPR007110
DomainSemaphorin

SEMA3A SEMA4D

5.30e-0420322IPR027231
DomainEGF_Ca-bd_CS

LTBP2 VWCE NCAN

6.04e-0497323IPR018097
DomainEGF_CA

LTBP2 VWCE NCAN

6.41e-0499323PS01187
DomainASX_HYDROXYL

LTBP2 VWCE NCAN

6.60e-04100323PS00010
DomainIGc2

SNHG28 ALPK3 SEMA4D SIGLEC1

6.66e-04235324SM00408
DomainIg_sub2

SNHG28 ALPK3 SEMA4D SIGLEC1

6.66e-04235324IPR003598
DomainEGF

LAMA5 LTBP2 VWCE NCAN

6.66e-04235324SM00181
DomainEGF-type_Asp/Asn_hydroxyl_site

LTBP2 VWCE NCAN

7.82e-04106323IPR000152
DomainEGF-like_dom

LAMA5 LTBP2 VWCE NCAN

8.27e-04249324IPR000742
DomainEGF_1

LAMA5 LTBP2 VWCE NCAN

9.03e-04255324PS00022
DomainEGF_CA

LTBP2 VWCE NCAN

1.17e-03122323SM00179
DomainEGF-like_Ca-bd_dom

LTBP2 VWCE NCAN

1.23e-03124323IPR001881
DomainSEMA

SEMA3A SEMA4D

1.28e-0331322PS51004
DomainSema

SEMA3A SEMA4D

1.28e-0331322SM00630
DomainSemap_dom

SEMA3A SEMA4D

1.28e-0331322IPR001627
DomainSema

SEMA3A SEMA4D

1.28e-0331322PF01403
DomainPSI

SEMA3A SEMA4D

2.57e-0344322IPR016201
DomainPSI

SEMA3A SEMA4D

2.81e-0346322SM00423
DomainV-set

SNHG28 SIGLEC1 NCAN

3.78e-03184323PF07686
Domainig

SEMA3A SEMA4D SIGLEC1

4.14e-03190323PF00047
DomainImmunoglobulin

SEMA3A SEMA4D SIGLEC1

4.14e-03190323IPR013151
DomainIg_V-set

SNHG28 SIGLEC1 NCAN

4.71e-03199323IPR013106
DomainEGF_3

LTBP2 VWCE NCAN

7.45e-03235323PS50026
DomainEGF_CA

LTBP2 VWCE

9.50e-0386322PF07645
DomainGalactose-bd-like

LAMA5 EPHA10

1.13e-0294322IPR008979
Pubmed

Candidate gene analysis of semaphorins in patients with Alzheimer's disease.

SEMA3A SEMA4D

9.84e-07235219957197
Pubmed

Expression Levels of Semaphorins 3A, 3B, 4A, and 4D on Human Peri-implantitis.

SEMA3A SEMA4D

5.90e-06435229763494
Pubmed

The sensory innervation of the mouse spinal cord may be patterned by differential expression of and differential responsiveness to semaphorins.

SEMA3A SEMA4D

3.53e-0593528812066
Pubmed

A feedback loop comprising lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitment.

DICER1 MBD1

3.53e-05935218604195
Pubmed

Inducible and constitutive transcription factors in the mammalian nervous system: control of gene expression by Jun, Fos and Krox, and CREB/ATF proteins.

JUNB EGR4

1.49e-04183529858769
Pubmed

Neurites from trigeminal ganglion explants grown in vitro are repelled or attracted by tooth-related tissues depending on developmental stage.

SEMA3A SEMA4D

1.66e-041935215051154
Pubmed

Multiple roles of lymphatic vessels in peripheral lymph node development.

LAMA5 SIGLEC1

1.85e-042035230355615
Pubmed

Impaired fetal muscle development and JAK-STAT activation mark disease onset and progression in a mouse model for merosin-deficient congenital muscular dystrophy.

LAMA5 AKIRIN1

2.24e-042235228334989
Pubmed

Morphogenesis in skin is governed by discrete sets of differentially expressed microRNAs.

LAMA5 DICER1

2.24e-042235216462742
Pubmed

A semaphorin code defines subpopulations of spinal motor neurons during mouse development.

SEMA3A SEMA4D

2.68e-042435215869472
Pubmed

Fezl regulates the differentiation and axon targeting of layer 5 subcortical projection neurons in cerebral cortex.

SEMA3A SEMA4D IGFBP4

2.79e-0412635316284245
Pubmed

Expression of Robo/Slit and Semaphorin/Plexin/Neuropilin family members in the developing hypothalamic paraventricular and supraoptic nuclei.

SEMA3A SEMA4D

3.66e-042835218617019
Pubmed

Noggin is required for correct guidance of dorsal root ganglion axons.

SEMA3A SEMA4D

3.93e-042935212435358
Pubmed

Compensatory Actions of Ldb Adaptor Proteins During Corticospinal Motor Neuron Differentiation.

SEMA3A IGFBP4

5.09e-043335226830346
Pubmed

RUNX1 and TGF-β signaling cross talk regulates Ca2+ ion channels expression and activity during megakaryocyte development.

JUNB LTBP2

5.73e-043535232281291
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

ZNF787 LAMA5 JUNB DENND2D PNPLA6 DICER1 MBD1

6.29e-04149735731527615
Pubmed

HIV-1 subtypes B and C Tat differentially impact synaptic plasticity expression and implicates HIV-associated neurocognitive disorders.

JUNB EGR4

6.76e-043835225613138
Cytoband1q23.2

SNHG28 VSIG8

3.31e-04353521q23.2
Cytoband1p34.3

AKIRIN1 EPHA10

1.04e-03623521p34.3
GeneFamilyImmunoglobulin like domain containing|Semaphorins

SEMA3A SEMA4D

2.65e-0420222736
GeneFamilyAdenosine receptors|V-set domain containing

VSIG8 SIGLEC1 NCAN

9.77e-04163223590
GeneFamilyImmunoglobulin like domain containing

ALPK3 SEMA3A SEMA4D

1.59e-03193223594
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

ALPK3 SIGLEC1

1.62e-02161222593
CoexpressionGROSS_HYPOXIA_VIA_ELK3_ONLY_DN

NAV1 LAMA5 IGFBP4

2.78e-0544353M1316
CoexpressionGROSS_HYPOXIA_VIA_ELK3_ONLY_DN

NAV1 LAMA5 IGFBP4

2.78e-0544353MM1128
CoexpressionNABA_CORE_MATRISOME

LAMA5 LTBP2 IGFBP4 VWCE NCAN

2.82e-05270355MM17057
CoexpressionNABA_CORE_MATRISOME

LAMA5 LTBP2 IGFBP4 VWCE NCAN

3.08e-05275355M5884
CoexpressionNABA_MATRISOME

SEMA3A LAMA5 SEMA4D LTBP2 ASTL IGFBP4 VWCE NCAN

4.34e-051008358MM17056
CoexpressionNABA_MATRISOME

SEMA3A LAMA5 SEMA4D LTBP2 ASTL IGFBP4 VWCE NCAN

4.92e-051026358M5889
CoexpressionNABA_ECM_GLYCOPROTEINS

LAMA5 LTBP2 IGFBP4 VWCE

1.20e-04191354MM17059
CoexpressionNABA_ECM_GLYCOPROTEINS

LAMA5 LTBP2 IGFBP4 VWCE

1.32e-04196354M3008
ToppCell356C-Myeloid-Monocyte-CD16+_Monocyte|356C / Donor, Lineage, Cell class and subclass (all cells)

SEMA3A ITPRIPL2 RAPH1 EGR4

7.42e-0616534435a6de30438de364ccca948fc932da541a69ef89
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-lymphocytic-T_lymphocytic|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SEMA4D JUNB DENND2D PARP8

1.17e-05185344115a74d0b9be580005d45d22d6e228801b2705e2
ToppCell3'-Child04-06-SmallIntestine-Hematopoietic-T_cells-gdT|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SEMA4D JUNB DENND2D PARP8

1.35e-05192344a0eb043d6f18f77c6135b4f313c3112529956f5b
ToppCelldroplet-Heart-4Chambers-21m-Endothelial-endocardial_endothelial_cells|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA3A SEMA4D IGFBP4 PARP8

1.40e-05194344c5e77650d7abee339ec38fa78a622bb124db3fa5
ToppCell10x_3'_v3-lymph_node_(10x_3'_v3)-lymphocytic-T_lymphocytic|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SEMA4D JUNB DENND2D PARP8

1.49e-05197344b044833de12f2b9eb702155563cd8932bc16e0ef
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-lymphocytic-T_lymphocytic-CD4-positive_helper_T_cell|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SEMA4D JUNB DENND2D PARP8

1.52e-05198344c4d8d133e571ad3a7c5de93aa7befb67cb7a003d
ToppCell5'-Adult-Appendix-Hematopoietic-T_cells|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SEMA4D JUNB DENND2D PARP8

1.52e-0519834433a09e67670fd4c3349a6aaec022b770ae49c9ad
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-lymphocytic-T_lymphocytic|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SEMA4D JUNB DENND2D PARP8

1.52e-05198344db107a5511571384f26e26c6301aef9a9f2423c4
ToppCell5'-Adult-LymphNode-Hematopoietic-T_cells|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SEMA4D JUNB DENND2D PARP8

1.58e-05200344cf4d184ff07862fabb182dabf09b2c9aac491409
ToppCellStriatum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb|Striatum / BrainAtlas - Mouse McCarroll V32

NAV1 DENND2D IGFBP4

5.20e-059534356350551af6a1ae15652d596002124d8f7885d4f
ToppCell390C-Lymphocytic-NK_cells-NK_cell_D|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

SNHG28 VSIG8 NCAN

1.18e-041253439e98dcfdc768ae492f453efc08926164bbb0a909
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Tac1_Htr1d|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SEMA3A DENND2D IGFBP4

1.61e-04139343fe1657ef9aeda7c530dc7febcd3dcd0e1d5f8a48
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Inner_Medullary_Collecting_Duct_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

JUNB LIPI NPAP1

2.22e-0415534329c4e9947bb4f7e257ed5c3bcf21bd67f88d473f
ToppCellPosterior_cortex|World / BrainAtlas - Mouse McCarroll V32

SEMA3A JUNB EGR4

2.39e-0415934318e9fe2efbe0bca7c3990f3b12b6f549e2c1263a
ToppCellControl-Treg|World / Disease group and Cell class

ZNF787 ALPK3 EGR4

2.48e-04161343ead9f5a491321f9e307f7c97e47a4ca124f59bb6
ToppCellChildren_(3_yrs)-Immune-dendritic_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

NAV1 VWCE EHHADH

2.48e-04161343cd41abb7ae659d3d314281783a0aaad562b26037
ToppCelldroplet-Fat-Scat-18m-Mesenchymal-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SIGLEC1 IGFBP4 EHHADH

2.57e-041633431eec7f5e5fed05fa21d3f81db588f10605f08ea7
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_VISp_Ctxn3_Brinp3|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SEMA3A IGFBP4 EPHA10

2.57e-04163343b0aa4a620bd58011225b42ea6dda04e3101ba342
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic-T_cells-Activated_T|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DENND2D WAS PARP8

2.71e-04166343fb2cfbf1d0a0f1950dd24c08ba00ebd64b06ceb4
ToppCell5'-Adult-SmallIntestine-Hematopoietic-T_cells-CD8_Tmem|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DENND2D WAS PARP8

2.76e-04167343d80b64322d16d98c82a52724809740b9de208f39
ToppCellPCW_05-06-Hematologic_Myeloid-Hem_Myeloid_macrophage-im_macrophage_(16)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

SIGLEC1 WAS ASTL

2.76e-041673430d187e40a5b96b595761f7aea1a0835462d8270f
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Monocytic-Non-classical_Monocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SIGLEC1 WAS LIPI

2.86e-04169343c3d410a5e98000ba872141b62e17ef4ed3d1a8eb
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage_4|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

SEMA3A SIGLEC1 ITPRIPL2

2.96e-041713437c8304573b892ef9ea4e048cba9ea9fbab848dcd
ToppCellLPS-IL1RA-Lymphocytic_NKT-T_cells-T-cells|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SEMA4D DENND2D WAS

2.96e-04171343539ea88acc6f948efdeae8b69e5c5ffaee29f1d9
ToppCell3'_v3-bone_marrow-Lymphocytic_Invariant-Inducer-like|bone_marrow / Manually curated celltypes from each tissue

JUNB IGFBP4 PARP8

2.96e-041713432977cffc146470733b5cfd8a1aa80d9346d4804d
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

SEMA4D LIPI PARP8

2.96e-041713432e9a20f8980b78325c52065a9c14ab3656267c05
ToppCell5'-GW_trimst-1.5-SmallIntestine-Hematopoietic-Myeloid-pDC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SIGLEC1 PNPLA6 WAS

3.01e-04172343d40a8bd61114b49a5837c836136a13c37c8f7de0
ToppCellLPS-IL1RA-Lymphocytic_NKT-T_cells|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SEMA4D DENND2D WAS

3.01e-041723430fc692be845d4225ff8b63bf9195724fc8510c2c
ToppCell10x5'-blood-Lymphocytic_Invariant-Inducer-like|blood / Manually curated celltypes from each tissue

JUNB IGFBP4 PARP8

3.11e-0417434351be6f29308c01593978cbee92114151a5916c9c
ToppCell343B-Myeloid-Macrophage-FABP4+_Macrophage|343B / Donor, Lineage, Cell class and subclass (all cells)

SIGLEC1 PNPLA6 VWCE

3.17e-04175343d3890bd0c570bb81434fdd1c5229891cefe2e462
ToppCellLPS-IL1RA+antiTNF-Lymphocytic_NKT-T_cells|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SEMA4D DENND2D WAS

3.22e-04176343bb41e9478373726eb460af764de0277b2d09928e
ToppCellLPS-IL1RA+antiTNF-Lymphocytic_NKT-T_cells-T-cells|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SEMA4D DENND2D WAS

3.22e-041763439d4a4dfeebb5a8a0f3ab18c37c8ddc2cd2158575
ToppCelltumor_Lymph_Node_/_Brain-T/NK_cells-Naive_CD8+_T|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

DENND2D WAS ASTL

3.27e-0417734322095eb7e87a822c35e3fb294eed30e6852bc6df
ToppCellLPS-IL1RA+antiTNF-Lymphocytic_NKT|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SEMA4D DENND2D WAS

3.27e-04177343f1efd9c3074d5635700fe7fbebf3dd0b1e0a84f1
ToppCellControl-Lymphocytic_NKT-T_cells-T-cells|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SEMA4D DENND2D WAS

3.33e-04178343910f8bea19d335455aba24e6a07b4834b709db5d
ToppCell3'_v3-bone_marrow-Lymphocytic_Invariant-Inducer-like-MAIT|bone_marrow / Manually curated celltypes from each tissue

JUNB IGFBP4 PARP8

3.33e-041783437ac71e245864be2e8daecf555ff68235bd05827c
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ALPK3 SIGLEC1 PNPLA6

3.33e-041783430b398656f26c4061b11ccf98908d0e2e1367585a
ToppCelldroplet-Lung-LUNG-30m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA5 IGFBP4 NCAN

3.38e-04179343a09647750eba9d93c5efc1db3b555fefb5eec7b5
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c08-GZMK-FOS_h|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

JUNB IGFBP4 PARP8

3.38e-04179343b0585a8e596c3d8e434af943e65207fa5877600d
ToppCell5'-GW_trimst-2-LymphNode-Hematopoietic-T_cells-TRDV2/TRGV9_gdT|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DENND2D C11orf16 PARP8

3.38e-04179343f7d3d37505893ae55065c89d957084602729decc
ToppCellControl-Lymphocytic_NKT-T_cells|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SEMA4D DENND2D WAS

3.38e-04179343d892d9496f1c33e23312092591eb2e968e736f7d
ToppCelltumor_Lymph_Node_/_Brain-Myeloid_cells-Activated_DCs|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

NAV1 EGR4 EHHADH

3.44e-04180343aae85fb3c92a45614616a3ee3a1af5244cc299a7
ToppCelldroplet-Spleen-nan-18m-Lymphocytic-T_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JUNB DENND2D IGFBP4

3.67e-041843438c23945bafe8926f25836bc208115edd5214a2b0
ToppCelldroplet-Lung-30m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LAMA5 IGFBP4 NCAN

3.67e-04184343f506d0ee48f39d6f59f19554217dfdf0987cc405
ToppCelldroplet-Lung-30m-Endothelial-arterial_endothelial|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LAMA5 IGFBP4 NCAN

3.67e-041843438bcb1c4bc8ffef74338cdade926a94711de93c64
ToppCellControl-Lymphocytic_NKT|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SEMA4D DENND2D WAS

3.73e-0418534359d68e119f58b35bab36294758f6b2e25fd8f5c0
ToppCelldroplet-Liver-LIVER_HEP-30m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAV1 LAMA5 DENND2D

3.73e-04185343bdd2e6cb20294b39a9d856004bf57ba69cf877e2
ToppCellControl-Myeloid-Macrophage_Alveolar|World / Disease state, Lineage and Cell class

ALPK3 SIGLEC1 PNPLA6

3.73e-0418534385cb81759589a26d83676cffbf2bc37399683c10
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-CD8_NK_sig|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

DENND2D WAS PARP8

3.79e-0418634371e87c4c755ab607689cb050f5a363cb520a0f53
ToppCell343B-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

LTBP2 ITPRIPL2 IGFBP4

3.79e-041863439673367cb53bafb873a01ef6bda11d9f392ce648
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SEMA3A SEMA4D JUNB

3.79e-041863438ea708070166c858cd9bd871670655b0114c32a5
ToppCellPCW_05-06-Hematologic_Myeloid-Hem_Myeloid_macrophage-im_immature_macrophage2_(0)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

SIGLEC1 DENND2D WAS

3.85e-04187343bde6b90955423eab6a91a0abe75d0a95a1f5330a
ToppCellControl-Fibroblasts-Pathological_FB|Control / group, cell type (main and fine annotations)

JUNB LTBP2 IGFBP4

3.85e-04187343b7280b8baa0fba9c2b4bff660c240ed96f6ff9b7
ToppCell10x5'v1-week_17-19-Lymphocytic_T-T_NK-NK_T_cell|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

VSIG8 DENND2D PARP8

3.85e-041873433301e0fca8c436d136c71f1a8fd59b3bb11bdd83
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c09-SLC4A10|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

JUNB IGFBP4 PARP8

3.85e-04187343f1ba41f2ec703251a81c46e08d45e70210f298e7
ToppCelldroplet-Heart-nan-3m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA3A SEMA4D VWCE

3.97e-041893438e583ec4df0f5b79ce5211cc99ecd8616d180bde
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_CCL3+-Alveolar_macrophage_CCL3+_L.1.0.2.4|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ALPK3 SIGLEC1 PNPLA6

3.97e-04189343a59025e82fabd9d60e2438dee85b2644478cc7c8
ToppCell5'-Adult-LymphNode-Hematopoietic-T_cells-NK_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DENND2D WAS PARP8

3.97e-041893435a9c3c61998efc40a5d2042e0f568b52103734a9
ToppCelldroplet-Heart-nan-3m-Endothelial-endocardial_endothelial_cells|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA3A SEMA4D VWCE

3.97e-04189343fb2253b8463d08b3d28e952a31a23dea2c2d986b
ToppCellPCW_10-12-Immune_Lymphocytic-Immune_Lymphocytic_B-im_lymphoid_progenitor_(7)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

SEMA4D DENND2D WAS

4.03e-04190343bee6a438e217b2abd57aef2a80a9fe14a298d223
ToppCell(1)_T_cells-(1)_T_CD4_fh|(1)_T_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)

SEMA4D JUNB IGFBP4

4.03e-04190343120ca702600373c208a3d032fede0a040736e5cf
ToppCell10x5'-blood-Lymphocytic_T_CD8-Trm/em_CD8|blood / Manually curated celltypes from each tissue

JUNB DENND2D PARP8

4.03e-04190343e1f474dc36bf9eaf457b14a8761d287904754cdc
ToppCellCOVID-19-Heart-T_cell|Heart / Disease (COVID-19 only), tissue and cell type

SEMA4D DENND2D PARP8

4.03e-04190343e6c3a6e01fef6c5b49f72661d4fb0414ba9046bf
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NAV1 SYT15B IGFBP4

4.09e-04191343f663131a4810584c5854bd64ee7991a237b7707f
ToppCellFetal_29-31_weeks-Immune-natural_killer_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SEMA4D DENND2D PARP8

4.09e-041913435696e2e2db7b898a1c7ab3582ae74cb712dd5bdf
ToppCellChildren_(3_yrs)-Immune-natural_killer_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

SEMA4D DENND2D PARP8

4.09e-041913439b8b64a36e27a2523b8730c7922fd7ad865a021e
ToppCell(1)_T_CD4_fh|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

SEMA4D JUNB DENND2D

4.09e-0419134366ddff9a99092cb384b9fb2a3ba95ddbebed67cc
ToppCell10x5'v1-week_17-19-Endothelial-stroma-proliferating_EC|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

SNHG28 ALPK3 IGFBP4

4.09e-04191343dc9e5eb6aa31b8d79aeec33e59b9138dfb469a3b
ToppCellChildren_(3_yrs)-Immune-natural_killer_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

SEMA4D DENND2D PARP8

4.09e-041913436345c1aa0fd2f9f2154a44f9393bf7c72bb1f44e
ToppCellMild/Remission-B_activate-7|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

JUNB IGFBP4 PARP8

4.09e-04191343382686d62f7b8576c44bb9726a4e10dc26fd348e
ToppCell5'-Adult-Distal_Rectal-Endothelial-blood_vessel_EC-Mature_venous_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAMA5 SYT15B IGFBP4

4.15e-04192343eafead22bba48ac5ee568faa8946c444445c1034
ToppCellImmune-natural_killer_cell|World / Lineage, Cell type, age group and donor

SEMA4D DENND2D PARP8

4.15e-0419234368121a6ef4115a93d87aad8802ef9b27d793d8c0
ToppCellkidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SEMA3A SYT15B IGFBP4

4.22e-04193343daefbfd3a3dd1351fbe94b9abfd807db44d56c24
ToppCellbackground-NK_cells|background / Sample and Cell Type and Tumor Cluster (all cells)

SEMA4D DENND2D PARP8

4.22e-04193343f8d6eff1e04926f85d265ec39fe66897fe29574d
ToppCellCOVID-19-kidney-T-cells-1|COVID-19 / Disease (COVID-19 only), tissue and cell type

SEMA4D DENND2D PARP8

4.22e-041933435b84fa640cf30dea55fde53b810f850ff946d253
ToppCellChildren_(3_yrs)-Immune-natural_killer_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

SEMA4D DENND2D PARP8

4.22e-041933431cb666375bc4e1b11a146d20896c9b5ae6fd0887
ToppCellmoderate-Myeloid-Monocyte-derived_Macrophage|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

SIGLEC1 IGFBP4 NCAN

4.22e-0419334322455801194bd8c73c5c397f5eac4f723429c383
ToppCell5'-GW_trimst-2-LymphNode-Hematopoietic-T_cells-NK_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DENND2D WAS PARP8

4.22e-04193343044fba87c4d10f4943a9f57315920280a4d097e7
ToppCell10x5'v1-week_17-19-Endothelial-stroma|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

ALPK3 SEMA3A IGFBP4

4.28e-04194343953578102ffc7b612ee8fce45e414750800fef5d
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NAV1 SYT15B IGFBP4

4.28e-04194343b490fffc94f005dff9a34ce34d80ca776e3a1387
ToppCelltumor_Lung|World / Location, Cell class and cell subclass

JUNB LTBP2 IGFBP4

4.28e-041943437e6b8a30f8d08252ad3f1df826d6f7c0ba997c2c
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NAV1 SYT15B IGFBP4

4.28e-04194343fa6d51f36a3dae8763a595c20892987ed454c0f0
ToppCell10x5'v1-week_17-19-Endothelial|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

ALPK3 SEMA3A IGFBP4

4.28e-04194343e141beafc9252e5d8c949252bfab53e127c881dc
ToppCellCOVID-19-lung-NK_cells|COVID-19 / Disease (COVID-19 only), tissue and cell type

SEMA4D DENND2D PARP8

4.28e-041943434c92f18e0a34fb50630d4b260eaf179202508b6d
ToppCellPCW_13-14-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_myeloid_progenitor1_(6)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

SIGLEC1 WAS ASTL

4.28e-04194343a062100ea6cd512a108f9036c259e0cd0f458563
ToppCellASK452-Endothelial-Lymphatic|Endothelial / Donor, Lineage and Cell class of Lung cells from Dropseq

SEMA3A LTBP2 RAPH1

4.35e-0419534320f492299a684ac1b7dd1bbc36a533cd6f9a1c93
ToppCell5'-Adult-LymphNode-Hematopoietic-T_cells-SELL+_CD8_T|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SEMA4D DENND2D PARP8

4.35e-0419534382561f6ed75ee33c2581fb25bd0997a9f0538cd8
ToppCellMonocytes-M2-like_CD16+_macrophages|World / Immune cells in Kidney/Urine in Lupus Nephritis

LTBP2 SIGLEC1 RAPH1

4.35e-0419534310fa47bdcf6c9784ea930b75a5861e139421feed
ToppCell343B-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

LTBP2 ITPRIPL2 IGFBP4

4.35e-0419534367b05a0cd2ca9924eca81a92cc6330eecb9d963c
ToppCelldroplet-Heart-4Chambers-21m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA4D IGFBP4 PARP8

4.35e-04195343df644b4c3ddccd34614ece5a2378000e6bc0fa10
ToppCellCOVID-19-lung-NK_cells|lung / Disease (COVID-19 only), tissue and cell type

SEMA4D DENND2D PARP8

4.35e-041953433b716ec7acc9a37af6bf40e711a539ce58d74aa4
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Mesenchymal-Pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA5 IGFBP4 C11orf16

4.41e-04196343184104cbea0461dd2757668ab9755948ac7b585a
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Mesenchymal-brain_pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA5 IGFBP4 C11orf16

4.41e-041963438114e98923096c54b6834f21550c3061bab6773d
ToppCellPCW_05-06-Hematologic_Myeloid|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

SIGLEC1 WAS ASTL

4.41e-04196343b2aee2f67da373a10b0c25e7797e30e3811543a8
ToppCellPCW_10-12-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_myeloid_progenitor1_(6)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

SIGLEC1 WAS ASTL

4.41e-04196343ce3709adbde7559b40c964888935914f66003247
ToppCellCaecum-T_cell-Tfh|T_cell / Region, Cell class and subclass

VSIG8 ASTL RAPH1

4.41e-04196343fe2ee5788028e6b671674f0cc50e2b6379f50976
ToppCell5'-Adult-LargeIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAMA5 SYT15B IGFBP4

4.48e-0419734387eda06344498dc66cac292cf89746dc90b5cf67
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.0.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DENND2D WAS PARP8

4.48e-041973430e93800d5df652a9c691c66a3f75a2e8979aed8e
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SEMA3A LAMA5 SEMA4D

4.48e-04197343ea746772adb9df4ddb0508d4ef35f2027bf09c35
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-6_mon-Macroglial|6_mon / Sample Type, Dataset, Time_group, and Cell type.

NAV1 IGFBP4 NCAN

4.48e-04197343965d5a3f8c9b12cb8a8d3429702ae29ebd8c6122
ComputationalPlacenta genes.

LAMA5 SEMA4D JUNB LTBP2 WAS IGFBP4

3.42e-05463166MODULE_38
ComputationalNeighborhood of PTPRC

SEMA4D WAS PARP8

1.28e-0468163GNF2_PTPRC
ComputationalLung genes.

LAMA5 JUNB LTBP2 WAS IGFBP4

3.16e-04434165MODULE_5
ComputationalNeighborhood of ATM

PMS2P11 WAS

7.13e-0427162GCM_ATM
ComputationalNeighborhood of CASP8

SEMA4D PARP8

7.13e-0427162GNF2_CASP8
ComputationalNeighborhood of SNRK

SEMA4D PARP8

7.68e-0428162GNF2_SNRK
ComputationalNeighborhood of AIP

PMS2P11 WAS

1.57e-0340162GCM_AIP
ComputationalNeighborhood of LTK

PMS2P11 WAS

2.07e-0346162GCM_LTK
ComputationalDRG (dorsal root ganglia) genes.

LAMA5 JUNB LTBP2 IGFBP4

2.07e-03384164MODULE_2
ComputationalNeighborhood of SELL

JUNB WAS

2.16e-0347162GNF2_SELL
ComputationalNeighborhood of VAV1

PMS2P11 WAS

2.16e-0347162GCM_VAV1
ComputationalNeighborhood of PRKAG1

PMS2P11 WAS

2.44e-0350162GCM_PRKAG1
ComputationalNeighborhood of ITGAL

SEMA4D PARP8

2.95e-0355162GNF2_ITGAL
ComputationalNeighborhood of PRKCG

PMS2P11 WAS

3.85e-0363162GCM_PRKCG
Diseaseotosclerosis

ALPK3 SEMA4D LTBP2 C11orf16

1.79e-0681324EFO_0004213
DiseaseMitral valve prolapse, response to surgery

ALPK3 LTBP2

7.47e-0512322EFO_0009951, HP_0001634
DiseaseMitral valve prolapse

ALPK3 LTBP2

7.01e-0436322HP_0001634
DiseaseSchizophrenia

SEMA3A NAV1 EGR4 DICER1 NCAN

2.44e-03883325C0036341
Diseaseserum alanine aminotransferase measurement, response to combination chemotherapy

SEMA4D RAPH1

2.70e-0371322EFO_0004735, EFO_0007965

Protein segments in the cluster

PeptideGeneStartEntry
GSPKRRRCAPLPGPT

AKIRIN1

21

Q9H9L7
APPGVSKPRCPGRAR

ALPK3

131

Q96L96
VPGRPGSTKRRQCYP

DICER1

736

Q9UPY3
LKLYGCSPSGPRPRG

ASTL

276

Q6HA08
YATLRRGPPPAPPKR

RAPH1

1226

Q70E73
PKTPAPDGPRYRFRK

PNPLA6

86

Q8IY17
LRRSPSYPPPGCGKS

PARP8

286

Q8N3A8
PKYGEPKRPPNCARG

MYADML2

256

A6NDP7
GPRLPRPPAPGREYC

KIAA1614

166

Q5VZ46
RPPAPGREYCNRGSP

KIAA1614

171

Q5VZ46
PGTPARKRGNRRYCP

EHHADH

546

Q08426
GAGSPPPYRRRKRPS

MBD1

396

Q9UIS9
RICNAPLPGPGPYRT

PMS2P11

141

Q13670
PRGECPKPGARAPRS

EGR4

56

Q05215
PPGFYKVSPRRPLCS

EPHA10

286

Q5JZY3
TPPPLLRFPGYRGCI

LAMA5

2886

O15230
PPAAPRPRGLLGRCY

LTBP2

541

Q14767
GYCRRLLPAGPGPRL

DENND2D

136

Q9H6A0
GGPRYLARCPPPRSQ

ITPRIPL2

511

Q3MIP1
PNLGKPSRIPRGPYA

NAV1

166

Q8NEY1
GLDPAGPRFSRKPPY

LIPI

181

Q6XZB0
YPIQTPRRRCGGPAP

NCAN

316

O14594
GRVPYPRPGTCPSKT

SEMA3A

371

Q14563
VRYNGPVPKPRPGAC

SEMA4D

356

Q92854
SGLRCYPPRGVEKPL

IGFBP4

76

P22692
SKFRPGCRRRPLPGP

NPAP1

6

Q9NZP6
RNGPEPCLGKPGTRY

C11orf16

391

Q9NQ32
LRRKYAPPPCGGPED

VSIG8

356

P0DPA2
ACKDRTPPPRFRPAG

RPS26P11

91

Q5JNZ5
GPPLCSPDGAPRRFK

SYT15B

86

X6R8R1
LPGAPARGYTGRKPP

VWCE

16

Q96DN2
RYRGLPAPGPSPADK

WAS

211

P42768
SYRCGVGPPGRAPRL

SIGLEC1

1146

Q9BZZ2
RSLRRKYAPPPCGGP

SNHG28

51

P0DPA3
AAGPRSRRAPAPKPY

ZNF787

266

Q6DD87
PYRSLKAPGARGPGP

JUNB

46

P17275