Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

ZNF502 ZNF93 ZNF132 ZNF383 ZNF527 ZNF672 ZNF493 ZNF607 ZNF678 ZNF268 ZNF175 ZNF423 RBPJL ZNF780B BCL11A ZNF784 ZBTB24 ZNF829 ZNF599 ZNF19 ZNF773 ZNF713 BCL11B ZNF37A ZNF792 ZNF780A ZNF43 ZNF587 RBAK ZNF256 ZFP1 ZNF814 ZNF264 SUZ12 ZNF30 ZNF107 ZNF99 ZNF417 NR1I3 ZNF304 ZNF445

1.16e-16145912741GO:0000977
GeneOntologyMolecularFunctionRNA polymerase II cis-regulatory region sequence-specific DNA binding

ZNF502 ZNF93 ZNF132 ZNF383 ZNF527 ZNF493 ZNF607 ZNF678 ZNF268 ZNF175 ZNF423 RBPJL ZNF780B BCL11A ZNF784 ZBTB24 ZNF829 ZNF773 ZNF713 BCL11B ZNF37A ZNF792 ZNF780A ZNF43 ZNF587 RBAK ZNF256 ZFP1 ZNF814 ZNF264 SUZ12 ZNF30 ZNF107 ZNF99 ZNF417 NR1I3 ZNF304 ZNF445

1.42e-16124412738GO:0000978
GeneOntologyMolecularFunctionDNA-binding transcription factor activity, RNA polymerase II-specific

ZNF502 ZNF93 ZNF132 ZNF383 ZNF527 ZNF672 ZNF493 ZNF607 ZNF678 ZNF268 ZNF175 ZNF423 RBPJL ZNF780B BCL11A ZNF784 ZBTB24 ZNF829 ZNF599 ZNF19 ZNF773 ZNF713 BCL11B ZNF37A ZNF792 ZNF780A ZNF43 ZNF587 RBAK ZNF256 ZFP1 ZNF814 ZNF264 ZNF30 ZNF107 ZNF99 ZNF417 NR1I3 ZNF304 ZNF445

2.35e-16141212740GO:0000981
GeneOntologyMolecularFunctioncis-regulatory region sequence-specific DNA binding

ZNF502 ZNF93 ZNF132 ZNF383 ZNF527 ZNF493 ZNF607 ZNF678 ZNF268 ZNF175 ZNF423 RBPJL ZNF780B BCL11A ZNF784 ZBTB24 ZNF829 ZNF773 ZNF713 BCL11B ZNF37A ZNF792 ZNF780A ZNF43 ZNF587 RBAK ZNF256 ZFP1 ZNF814 ZNF264 SUZ12 ZNF30 ZNF107 ZNF99 ZNF417 NR1I3 ZNF304 ZNF445

2.86e-16127112738GO:0000987
GeneOntologyMolecularFunctionglycogen phosphorylase activity

PYGB PYGL PYGM

2.51e-0731273GO:0008184
GeneOntologyMolecularFunction1,4-alpha-oligoglucan phosphorylase activity

PYGB PYGL PYGM

2.49e-0651273GO:0004645
GeneOntologyMolecularFunctionDNA-binding transcription activator activity, RNA polymerase II-specific

ZNF493 ZNF268 ZNF175 RBPJL ZNF780B ZNF784 BCL11B ZNF780A ZNF43 ZNF814 ZNF107 ZNF99 NR1I3 ZNF445

1.34e-0556012714GO:0001228
GeneOntologyMolecularFunctionDNA-binding transcription activator activity

ZNF493 ZNF268 ZNF175 RBPJL ZNF780B ZNF784 BCL11B ZNF780A ZNF43 ZNF814 ZNF107 ZNF99 NR1I3 ZNF445

1.51e-0556612714GO:0001216
GeneOntologyMolecularFunctionDNA-binding transcription repressor activity, RNA polymerase II-specific

ZNF93 ZNF493 ZNF175 BCL11A ZBTB24 ZNF43 ZNF107 ZNF99

1.03e-033201278GO:0001227
GeneOntologyMolecularFunctionDNA-binding transcription repressor activity

ZNF93 ZNF493 ZNF175 BCL11A ZBTB24 ZNF43 ZNF107 ZNF99

1.16e-033261278GO:0001217
GeneOntologyBiologicalProcesstransposable element silencing

ZNF93 ZNF493 ZNF43 ZNF107 ZNF99

9.16e-06461275GO:0010526
GeneOntologyBiologicalProcessretrotransposition

ZNF93 ZNF493 ZNF43 ZNF107 ZNF99

1.13e-05481275GO:0032197
GeneOntologyBiologicalProcesstransposition

ZNF93 ZNF493 ZNF43 ZNF107 ZNF99

1.39e-05501275GO:0032196
GeneOntologyCellularComponentmultimerin complex

MMRN1 MMRN2

3.78e-0521292GO:1990972
GeneOntologyCellularComponentequatorial microtubule organizing center

TUBGCP4 TUBGCP5

3.73e-0451292GO:0000923
DomainZINC_FINGER_C2H2_2

ZNF502 ZNF93 ZNF132 ZNF383 ZNF527 ZNF672 ZNF493 ZNF607 ZNF678 ZNF268 ZNF175 ZNF423 ZNF780B BCL11A ZNF235 ZNF784 ZBTB24 ZNF829 ZNF599 ZNF19 ZNF773 ZNF713 BCL11B ZNF37A ZNF792 ZNF780A ZNF43 ARID2 ZNF587 RBAK ZNF256 ZFP1 ZNF814 ZNF264 SUZ12 ZNF30 ZNF107 ZNF99 ZNF417 ZNF304 ZNF445

6.93e-2677512641PS50157
DomainZINC_FINGER_C2H2_1

ZNF502 ZNF93 ZNF132 ZNF383 ZNF527 ZNF672 ZNF493 ZNF607 ZNF678 ZNF268 ZNF175 ZNF423 ZNF780B BCL11A ZNF235 ZNF784 ZBTB24 ZNF829 ZNF599 ZNF19 ZNF773 ZNF713 BCL11B ZNF37A ZNF792 ZNF780A ZNF43 ARID2 ZNF587 RBAK ZNF256 ZFP1 ZNF814 ZNF264 SUZ12 ZNF30 ZNF107 ZNF99 ZNF417 ZNF304 ZNF445

7.66e-2677712641PS00028
Domainzf-C2H2

ZNF502 ZNF93 ZNF132 ZNF383 ZNF527 ZNF672 ZNF493 ZNF607 ZNF678 ZNF268 ZNF175 ZNF423 ZNF780B BCL11A ZNF235 ZNF784 ZBTB24 ZNF829 ZNF599 ZNF19 ZNF773 ZNF713 BCL11B ZNF37A ZNF792 ZNF780A ZNF43 ZNF587 RBAK ZNF256 ZFP1 ZNF814 ZNF264 ZNF30 ZNF107 ZNF99 ZNF417 ZNF304 ZNF445

1.50e-2569312639PF00096
DomainZnF_C2H2

ZNF502 ZNF93 ZNF132 ZNF383 ZNF527 ZNF672 ZNF493 ZNF607 ZNF678 ZNF268 ZNF175 ZNF423 ZNF780B BCL11A ZNF235 ZNF784 ZBTB24 ZNF829 ZNF599 ZNF19 ZNF773 ZNF713 BCL11B ZNF37A ZNF792 ZNF780A ZNF43 ARID2 ZNF587 RBAK ZNF256 ZFP1 ZNF814 ZNF264 SUZ12 ZNF30 ZNF107 ZNF99 ZNF417 ZNF304 ZNF445

3.44e-2580812641SM00355
DomainZnf_C2H2/integrase_DNA-bd

ZNF502 ZNF93 ZNF132 ZNF383 ZNF527 ZNF672 ZNF493 ZNF607 ZNF268 ZNF175 ZNF423 ZNF780B BCL11A ZNF235 ZNF784 ZBTB24 ZNF829 ZNF599 ZNF19 ZNF773 ZNF713 BCL11B ZNF37A ZNF792 ZNF780A ZNF43 ZNF587 RBAK ZNF256 ZFP1 ZNF814 ZNF264 ZNF30 ZNF107 ZNF99 ZNF417 ZNF304 ZNF445

1.92e-2469412638IPR013087
DomainZnf_C2H2-like

ZNF502 ZNF93 ZNF132 ZNF383 ZNF527 ZNF672 ZNF493 ZNF607 ZNF268 ZNF175 ZNF423 ZNF780B BCL11A ZNF235 ZNF784 ZBTB24 ZNF829 ZNF599 ZNF19 ZNF773 ZNF713 BCL11B ZNF37A ZNF792 ZNF780A ZNF43 ARID2 ZNF587 RBAK ZNF256 ZFP1 ZNF814 ZNF264 SUZ12 ZNF30 ZNF107 ZNF99 ZNF417 ZNF304 ZNF445

2.18e-2479612640IPR015880
DomainZnf_C2H2

ZNF502 ZNF93 ZNF132 ZNF383 ZNF527 ZNF672 ZNF493 ZNF607 ZNF678 ZNF268 ZNF175 ZNF423 ZNF780B BCL11A ZNF235 ZNF784 ZBTB24 ZNF829 ZNF599 ZNF19 ZNF773 ZNF713 BCL11B ZNF37A ZNF792 ZNF780A ZNF43 ARID2 ZNF587 RBAK ZNF256 ZFP1 ZNF814 ZNF264 ZNF30 ZNF107 ZNF99 ZNF417 ZNF304 ZNF445

3.32e-2480512640IPR007087
Domain-

ZNF502 ZNF93 ZNF132 ZNF383 ZNF527 ZNF672 ZNF493 ZNF607 ZNF268 ZNF175 ZNF423 ZNF780B BCL11A ZNF235 ZNF784 ZBTB24 ZNF829 ZNF599 ZNF19 ZNF773 BCL11B ZNF37A ZNF792 ZNF780A ZNF43 ZNF587 RBAK ZNF256 ZFP1 ZNF814 ZNF264 ZNF30 ZNF107 ZNF99 ZNF417 ZNF304 ZNF445

1.05e-23679126373.30.160.60
DomainKRAB

ZNF93 ZNF132 ZNF383 ZNF527 ZNF607 ZNF268 ZNF175 ZNF780B ZNF235 ZNF829 ZNF599 ZNF19 ZNF773 ZNF713 ZNF37A ZNF792 ZNF780A ZNF43 ZNF587 RBAK ZNF256 ZFP1 ZNF814 ZNF264 ZNF30 ZNF99 ZNF417 ZNF304 ZNF445

2.62e-2335812629PS50805
DomainKRAB

ZNF93 ZNF132 ZNF383 ZNF527 ZNF607 ZNF268 ZNF175 ZNF780B ZNF235 ZNF829 ZNF599 ZNF19 ZNF773 ZNF713 ZNF37A ZNF792 ZNF780A ZNF43 ZNF587 RBAK ZNF256 ZFP1 ZNF814 ZNF264 ZNF30 ZNF99 ZNF417 ZNF304 ZNF445

2.62e-2335812629PF01352
DomainKRAB

ZNF93 ZNF132 ZNF383 ZNF527 ZNF607 ZNF268 ZNF175 ZNF780B ZNF235 ZNF829 ZNF599 ZNF19 ZNF773 ZNF713 ZNF37A ZNF792 ZNF780A ZNF43 ZNF587 RBAK ZNF256 ZFP1 ZNF814 ZNF264 ZNF30 ZNF99 ZNF417 ZNF304 ZNF445

6.16e-2336912629SM00349
DomainKRAB

ZNF93 ZNF132 ZNF383 ZNF527 ZNF607 ZNF268 ZNF175 ZNF780B ZNF235 ZNF829 ZNF599 ZNF19 ZNF773 ZNF713 ZNF37A ZNF792 ZNF780A ZNF43 ZNF587 RBAK ZNF256 ZFP1 ZNF814 ZNF264 ZNF30 ZNF99 ZNF417 ZNF304 ZNF445

6.65e-2337012629IPR001909
Domainzf-C2H2_6

ZNF502 ZNF93 ZNF527 ZNF672 ZNF493 ZNF607 ZNF423 ZNF780B ZBTB24 ZNF773 ZNF792 ZNF780A ZNF43 ZNF587 ZNF256 ZNF814 ZNF30 ZNF107 ZNF99 ZNF417 ZNF445

2.45e-1531412621PF13912
DomainPHOSPHORYLASE

PYGB PYGL PYGM

3.00e-0731263PS00102
DomainPhosphorylase

PYGB PYGL PYGM

3.00e-0731263PF00343
DomainGlycg_phsphrylas

PYGB PYGL PYGM

3.00e-0731263IPR011833
DomainGlyco_trans_35

PYGB PYGL PYGM

3.00e-0731263IPR000811
DomainSerpin_CS

SERPINB10 SERPINB3 SERPINB4 SERPINB12

6.13e-05321264IPR023795
DomainSerpin_dom

SERPINB10 SERPINB3 SERPINB4 SERPINB12

9.84e-05361264IPR023796
Domainzf-H2C2_2

ZNF383 ZNF599 ZFP1

1.03e-04141263PF13465
DomainSERPIN

SERPINB10 SERPINB3 SERPINB4 SERPINB12

1.10e-04371264SM00093
DomainSERPIN

SERPINB10 SERPINB3 SERPINB4 SERPINB12

1.10e-04371264PS00284
DomainSerpin

SERPINB10 SERPINB3 SERPINB4 SERPINB12

1.22e-04381264PF00079
DomainSerpin_fam

SERPINB10 SERPINB3 SERPINB4 SERPINB12

1.35e-04391264IPR000215
DomainGCP

TUBGCP4 TUBGCP5

4.46e-0451262IPR007259
DomainSpc97_Spc98

TUBGCP4 TUBGCP5

4.46e-0451262PF04130
DomainAnoct_dimer

ANO4 ANO3

9.27e-0471262PF16178
DomainAnoct_dimer

ANO4 ANO3

9.27e-0471262IPR032394
DomainAnoctamin

ANO4 ANO3

1.96e-03101262PF04547
DomainAnoctamin

ANO4 ANO3

1.96e-03101262IPR007632
DomainEMI

MMRN1 MMRN2

1.96e-03101262PF07546
PathwayREACTOME_RNA_POLYMERASE_II_TRANSCRIPTION

ZNF383 ZNF493 GAMT ZNF607 ZNF678 ZNF268 ZNF175 INTS1 ZNF235 ZNF599 ZNF19 ZNF773 ZNF713 ZNF37A ZNF792 ZNF43 ARID2 ZNF587 ZNF256 ZFP1 ZNF264 SUZ12 ZNF30 ZNF99 ZNF417 NR1I3 ZNF304 ZNF445

5.33e-07138710428M734
PathwayKEGG_MEDICUS_REFERENCE_GLYCOGEN_DEGRADATION

PYGB PYGL PYGM

3.17e-0591043M47621
PathwayREACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS

PYGB PYGL PYGM

1.34e-04141043M19193
PathwayREACTOME_GENERIC_TRANSCRIPTION_PATHWAY

ZNF93 ZNF383 ZNF493 ZNF268 ZNF780B ZNF235 ZNF773 ZNF780A ZNF43 ZFP1 ZNF814 SUZ12 ZNF107 ZNF99 NR1I3 ZNF445

1.52e-0476810416MM14851
PathwayREACTOME_GENE_EXPRESSION_TRANSCRIPTION

ZNF93 ZNF383 IPO8 ZNF493 ZNF268 ZNF780B INTS1 ZNF235 ZNF773 ZNF780A ZNF43 ZFP1 ZNF814 SUZ12 ZNF107 ZNF99 NUP160 NR1I3 ZNF445

1.54e-04102210419MM15436
Pubmed

Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.

ZNF93 ZNF383 ZNF493 ZNF607 ZNF678 ZNF235 ZNF792 ZNF780A ZNF587 ZFP1 ZNF264 ZNF107 ZNF417 ZNF445

8.31e-151811301437372979
Pubmed

Rapid and efficient cloning of cDNAs encoding Krüppel-like zinc finger proteins by degenerate PCR.

ZNF493 ZNF175 ZNF43 ZNF814 ZNF107 ZNF99 ZNF445

6.53e-104913079630514
Pubmed

Expansion and diversification of KRAB zinc-finger genes within a cluster including Regulator of sex-limitation 1 and 2.

ZNF93 ZNF493 ZNF43 ZNF107 ZNF99

1.97e-0915130515885501
Pubmed

Functional analysis of the SRY-KRAB interaction in mouse sex determination.

ZNF493 ZNF43 ZNF107 ZNF99

3.85e-0810130418588511
Pubmed

Comparative genomic analysis of the clade B serpin cluster at human chromosome 18q21: amplification within the mouse squamous cell carcinoma antigen gene locus.

SERPINB10 SERPINB3 SERPINB4 SERPINB12

6.03e-0811130415203215
Pubmed

Sry associates with the heterochromatin protein 1 complex by interacting with a KRAB domain protein.

ZNF493 ZNF43 ZNF107 ZNF99

6.03e-0811130415469996
Pubmed

Regulator of sex-limitation (Rsl) encodes a pair of KRAB zinc-finger genes that control sexually dimorphic liver gene expression.

ZNF93 ZNF493 ZNF43 ZNF107 ZNF99

7.46e-0829130514563677
Pubmed

Multiple genes encoding zinc finger domains are expressed in human T cells.

ZNF19 ZNF37A ZNF43 ZFP1 ZNF30

1.06e-073113052288909
Pubmed

Epigenetic gene silencing by the SRY protein is mediated by a KRAB-O protein that recruits the KAP1 co-repressor machinery.

ZNF493 ZNF43 ZNF107 ZNF99

1.30e-0713130419850934
Pubmed

Clustered organization of homologous KRAB zinc-finger genes with enhanced expression in human T lymphoid cells.

ZNF93 ZNF43 ZNF107 ZNF99

3.28e-071613048467795
Pubmed

Human POGZ modulates dissociation of HP1alpha from mitotic chromosome arms through Aurora B activation.

IPO8 ZNF829 ZNF773 ZFP1 ZNF264 SUZ12

7.24e-0783130620562864
Pubmed

The amplified mouse squamous cell carcinoma antigen gene locus contains a serpin (Serpinb3b) that inhibits both papain-like cysteine and trypsin-like serine proteinases.

SERPINB3 SERPINB4

1.39e-052130215203214
Pubmed

Increased Th1 immune response in SERPINB3 transgenic mice during acute liver failure.

SERPINB3 SERPINB4

1.39e-052130223354406
Pubmed

Serpin B4 isoform overexpression is associated with aberrant epithelial proliferation and lung cancer in idiopathic pulmonary fibrosis.

SERPINB3 SERPINB4

1.39e-052130222406480
Pubmed

Recurrent SERPINB3 and SERPINB4 mutations in patients who respond to anti-CTLA4 immunotherapy.

SERPINB3 SERPINB4

1.39e-052130227668655
Pubmed

COUP-TF (chicken ovalbumin upstream promoter transcription factor)-interacting protein 1 (CTIP1) is a sequence-specific DNA binding protein.

BCL11A BCL11B

1.39e-052130212196208
Pubmed

Characterization of novel squamous cell carcinoma antigen-related molecules in mice.

SERPINB3 SERPINB4

1.39e-052130215504361
Pubmed

SCCA2-like serpins mediate genetic predisposition to skin tumors.

SERPINB3 SERPINB4

1.39e-052130212702576
Pubmed

Serpinb3 is overexpressed in the liver in presence of iron overload.

SERPINB3 SERPINB4

1.39e-052130228935635
Pubmed

Lysoptosis is an evolutionarily conserved cell death pathway moderated by intracellular serpins.

SERPINB3 SERPINB4

1.39e-052130235022507
Pubmed

Overexpression of SERPIN B3 promotes epithelial proliferation and lung fibrosis in mice.

SERPINB3 SERPINB4

1.39e-052130221403642
Pubmed

The BCL11 gene family: involvement of BCL11A in lymphoid malignancies.

BCL11A BCL11B

1.39e-052130211719382
Pubmed

CTIP1 and CTIP2 are differentially expressed during mouse embryogenesis.

BCL11A BCL11B

1.39e-052130215465497
Pubmed

SERPINB3/B4 contributes to early inflammation and barrier dysfunction in an experimental murine model of atopic dermatitis.

SERPINB3 SERPINB4

1.39e-052130225111616
Pubmed

Molecular cloning of human squamous cell carcinoma antigen 1 gene and characterization of its promoter.

SERPINB3 SERPINB4

1.39e-052130211267667
Pubmed

Squamous Cell Carcinoma Antigen-encoding Genes SERPINB3/B4 as Potentially Useful Markers for the Stratification of HNSCC Tumours.

SERPINB3 SERPINB4

1.39e-052130229491058
Pubmed

Isoform-selective regulation of glycogen phosphorylase by energy deprivation and phosphorylation in astrocytes.

PYGB PYGM

1.39e-052130225130497
Pubmed

Squamous cell carcinoma antigen production in nasal inverted papilloma.

SERPINB3 SERPINB4

1.39e-052130223168150
Pubmed

The serpin SQN-5 is a dual mechanistic-class inhibitor of serine and cysteine proteinases.

SERPINB3 SERPINB4

1.39e-052130211863458
Pubmed

IgM-linked SerpinB3 and SerpinB4 in sera of patients with chronic liver disease.

SERPINB3 SERPINB4

1.39e-052130222808225
Pubmed

Overexpression of squamous cell carcinoma antigen variants in hepatocellular carcinoma.

SERPINB3 SERPINB4

1.39e-052130214970861
Pubmed

Co-expression of the squamous cell carcinoma antigens 1 and 2 in normal adult human tissues and squamous cell carcinomas.

SERPINB3 SERPINB4

1.39e-052130210653592
Pubmed

Serum squamous cell carcinoma antigen as an early indicator of response during therapy of cervical cancer.

SERPINB3 SERPINB4

1.39e-052130229112685
Pubmed

Circulating serpin tumor markers SCCA1 and SCCA2 are not actively secreted but reside in the cytosol of squamous carcinoma cells.

SERPINB3 SERPINB4

1.39e-052130210956412
Pubmed

Tumor-related protein, the squamous cell carcinoma antigen binds to the intracellular protein carbonyl reductase.

SERPINB3 SERPINB4

1.39e-052130220428762
Pubmed

SerpinB3 as a Pro-Inflammatory Mediator in the Progression of Experimental Non-Alcoholic Fatty Liver Disease.

SERPINB3 SERPINB4

1.39e-052130235874657
Pubmed

Gene variants in the novel type 2 diabetes loci CDC123/CAMK1D, THADA, ADAMTS9, BCL11A, and MTNR1B affect different aspects of pancreatic beta-cell function.

WFS1 BCL11A THADA

1.80e-0514130319833888
Pubmed

Update of the human and mouse SERPIN gene superfamily.

SERPINB10 SERPINB3 SERPINB4 SERPINB12

2.05e-0543130424172014
Pubmed

Localization of the muscle, liver, and brain glycogen phosphorylase genes on linkage maps of mouse chromosomes 19, 12, and 2, respectively.

PYGB PYGL PYGM

2.25e-051513032575583
Pubmed

Serpin B3/B4, activated by STAT3, promote survival of squamous carcinoma cells.

SERPINB3 SERPINB4

4.15e-053130219070595
Pubmed

A murine ortholog of the human serpin SCCA2 maps to chromosome 1 and inhibits chymotrypsin-like serine proteinases.

SERPINB3 SERPINB4

4.15e-05313029828132
Pubmed

Anti-apoptotic effects of SERPIN B3 and B4 via STAT6 activation in macrophages after infection with Toxoplasma gondii.

SERPINB3 SERPINB4

4.15e-053130222451727
Pubmed

A serine proteinase inhibitor locus at 18q21.3 contains a tandem duplication of the human squamous cell carcinoma antigen gene.

SERPINB3 SERPINB4

4.15e-05313027724531
Pubmed

Differentially expressed proteins in human breast cancer cells sensitive and resistant to paclitaxel.

SERPINB3 SERPINB4

4.15e-053130224898082
Pubmed

A nonredundant role for mouse Serpinb3a in the induction of mucus production in asthma.

SERPINB3 SERPINB4

4.15e-053130221126757
Pubmed

Diagnostic and prognostic role of SCCA-IgM serum levels in hepatocellular carcinoma (HCC).

SERPINB3 SERPINB4

4.15e-053130224635038
Pubmed

Heparin enhances serpin inhibition of the cysteine protease cathepsin L.

SERPINB3 SERPINB4

4.15e-053130219959474
Pubmed

Uteroglobin suppresses SCCA gene expression associated with allergic asthma.

SERPINB3 SERPINB4

4.15e-053130215677460
Pubmed

Regulation of pulmonary fibrosis by chemokine receptor CXCR3.

BCL11A BCL11B

4.15e-053130215254596
Pubmed

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.

ZNF502 IPO5 IPO8 WFS1 CIP2A INTS1 PEX13 TBC1D24 ZNF773 TBC1D4 UTP4 RBAK ZNF417 NUP160 ABHD16A

4.58e-0512031301529180619
Pubmed

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.

ZNF93 ZNF175 ZNF423 ZNF235 ZBTB24 ZNF773 ZNF43 ARID2 ZMIZ2 RBAK ZNF99 ZNF445

5.38e-058081301220412781
Pubmed

Requirement for phosphatidylinositol transfer protein in epidermal growth factor signaling.

PI4KA PITPNA

8.28e-05413027761838
Pubmed

Developmental cell death of cortical projection neurons is controlled by a Bcl11a/Bcl6-dependent pathway.

BCL11A BCL11B

8.28e-054130235766181
Pubmed

Serpin squamous cell carcinoma antigen inhibits UV-induced apoptosis via suppression of c-JUN NH2-terminal kinase.

SERPINB3 SERPINB4

8.28e-054130216549498
Pubmed

Inhibitory mechanism of a cross-class serpin, the squamous cell carcinoma antigen 1.

SERPINB3 SERPINB4

8.28e-054130212949073
Pubmed

Squamous cell carcinoma antigen 1 promotes caspase-8-mediated apoptosis in response to endoplasmic reticulum stress while inhibiting necrosis induced by lysosomal injury.

SERPINB3 SERPINB4

8.28e-054130221576355
Pubmed

Isolation of a novel family of C(2)H(2) zinc finger proteins implicated in transcriptional repression mediated by chicken ovalbumin upstream promoter transcription factor (COUP-TF) orphan nuclear receptors.

BCL11A BCL11B

8.28e-054130210744719
Pubmed

FLJ10261 gene, located within the CCND1-EMS1 locus on human chromosome 11q13, encodes the eight-transmembrane protein homologous to C12orf3, C11orf25 and FLJ34272 gene products.

ANO4 ANO3

8.28e-054130212739008
Pubmed

Use of multiple metabolic and genetic markers to improve the prediction of type 2 diabetes: the EPIC-Potsdam Study.

WFS1 BCL11A THADA

8.56e-0523130319720844
Pubmed

The DNA sequence and biology of human chromosome 19.

ZNF93 GAMT ZNF175 ZNF780B ZNF780A ZNF814 ZNF264

1.01e-04284130715057824
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

IPO5 INTS1 DDX55 ZBTB24 ZNF780A ARID2 UTP4 RBAK ZFP1 SUZ12

1.01e-046081301036089195
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

IPO5 IPO8 POC1A TUBGCP4 TUBGCP5 SERPINB12 ARID2 RBAK ZFP1 FAM83D PYGM GNAO1 NUP160 NSMCE4A

1.12e-0411551301420360068
Pubmed

Analysis of a lung defect in autophagy-deficient mouse strains.

PYGB PYGL PYGM

1.25e-0426130324275123
Pubmed

GCP5 and GCP6: two new members of the human gamma-tubulin complex.

TUBGCP4 TUBGCP5

1.38e-045130211694571
Pubmed

New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.

SETMAR SIDT1 TUBGCP5 OMG BCL11B ADAMTS6 ASXL3 TENM1 SMG6

1.40e-04513130925798074
Pubmed

Characterising the dynamics of placental glycogen stores in the mouse.

PYGB PYGL PYGM

1.74e-0429130332798765
Pubmed

Overlapping, complementary and site-specific expression pattern of genes of the EMILIN/Multimerin family.

MMRN1 MMRN2

2.06e-046130214996434
Pubmed

Proteomic and bioinformatic analysis of mammalian SWI/SNF complexes identifies extensive roles in human malignancy.

BCL11A BCL11B

2.06e-046130223644491
Pubmed

Identification and characterization of TMEM16E and TMEM16F genes in silico.

ANO4 ANO3

2.06e-046130215067359
Pubmed

Signal recognition particle protein 19 is imported into the nucleus by importin 8 (RanBP8) and transportin.

IPO5 IPO8

2.88e-047130211682607
Pubmed

Strict in vivo specificity of the Bcl11a erythroid enhancer.

BCL11A BCL11B

2.88e-047130227707736
Pubmed

Developmental expression and biochemical characterization of Emu family members.

MMRN1 MMRN2

2.88e-047130212221002
Pubmed

UBE2O and USP7 co-regulate RECQL4 ubiquitinylation and homologous recombination-mediated DNA repair.

IPO5 ZNF672 ZNF587 SUZ12 PLD1

3.01e-04155130534921745
Pubmed

The evolutionarily conserved Krüppel-associated box domain defines a subfamily of eukaryotic multifingered proteins.

ZNF93 ZNF43

3.83e-04813022023909
Pubmed

NRXN3 is a novel locus for waist circumference: a genome-wide association study from the CHARGE Consortium.

OVCH2 PKHD1

3.83e-048130219557197
Pubmed

Importin 8 mediates m7G cap-sensitive nuclear import of the eukaryotic translation initiation factor eIF4E.

IPO5 IPO8

3.83e-048130227114554
Pubmed

Mouse models characterize GNAO1 encephalopathy as a neurodevelopmental disorder leading to motor anomalies: from a severe G203R to a milder C215Y mutation.

BCL11B GNAO1

3.83e-048130235090564
Pubmed

Genetic risk reclassification for type 2 diabetes by age below or above 50 years using 40 type 2 diabetes risk single nucleotide polymorphisms.

WFS1 BCL11A THADA

4.90e-0441130320889853
Pubmed

The Specification of Cortical Subcerebral Projection Neurons Depends on the Direct Repression of TBR1 by CTIP1/BCL11a.

BCL11A BCL11B

4.91e-049130225972180
Pubmed

Direct binding of NuMA to tubulin is mediated by a novel sequence motif in the tail domain that bundles and stabilizes microtubules.

TUBGCP4 TUBGCP5

4.91e-049130211956313
Pubmed

Dynamic changes of NuMA during the cell cycle and possible appearance of a truncated form of NuMA during apoptosis.

TUBGCP4 TUBGCP5

4.91e-04913028838651
Pubmed

Novel meta-analysis-derived type 2 diabetes risk loci do not determine prediabetic phenotypes.

BCL11A THADA

4.91e-049130218714373
Pubmed

Neural-specific deletion of the focal adhesion adaptor protein paxillin slows migration speed and delays cortical layer formation.

BCL11A BCL11B

4.91e-049130228935710
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

ATP13A1 CIP2A TUBGCP5 SEMA4G THADA ARID2 UTP4 NUP160

5.54e-04493130815368895
Pubmed

Shifts in the vascular endothelial growth factor isoforms result in transcriptome changes correlated with early neural stem cell proliferation and differentiation in mouse forebrain.

BCL11B SUZ12

6.12e-0410130224124161
Pubmed

Anoctamin/TMEM16 family members are Ca2+-activated Cl- channels.

ANO4 ANO3

6.12e-0410130219015192
Pubmed

Calcium-dependent phospholipid scramblase activity of TMEM16 protein family members.

ANO4 ANO3

6.12e-0410130223532839
Pubmed

Genome-wide association study for serum urate concentrations and gout among African Americans identifies genomic risk loci and a novel URAT1 loss-of-function allele.

PYGM RASGRP2

6.12e-0410130221768215
Pubmed

CDK5RAP2 stimulates microtubule nucleation by the gamma-tubulin ring complex.

TUBGCP4 TUBGCP5

6.12e-0410130221135143
Pubmed

BCL11B functionally associates with the NuRD complex in T lymphocytes to repress targeted promoter.

BCL11A BCL11B

6.12e-0410130216091750
Pubmed

Structure and function of TMEM16 proteins (anoctamins).

ANO4 ANO3

6.12e-0410130224692353
Pubmed

A census of human transcription factors: function, expression and evolution.

ZNF268 ZNF175 RBPJL ZBTB24 ZNF19 BCL11B ZNF37A ZNF43 RBAK ZNF30 NR1I3

6.27e-049081301119274049
Pubmed

Probing the interaction between the histone methyltransferase/deacetylase subunit RBBP4/7 and the transcription factor BCL11A in epigenetic complexes.

BCL11A SUZ12

7.46e-0411130229263092
Pubmed

Lack of significant effects of the type 2 diabetes susceptibility loci JAZF1, CDC123/CAMK1D, NOTCH2, ADAMTS9, THADA, and TSPAN8/LGR5 on diabetes and quantitative metabolic traits.

BCL11A THADA

7.46e-0411130219670153
Pubmed

Cell Type-Specific Role of RNA Nuclease SMG6 in Neurogenesis.

BCL11B SMG6

7.46e-0411130234943873
Pubmed

Mutations in RNF135, a gene within the NF1 microdeletion region, cause phenotypic abnormalities including overgrowth.

OMG SUZ12

8.93e-0412130217632510
Pubmed

Maintenance of silent chromatin through replication requires SWI/SNF-like chromatin remodeler SMARCAD1.

ZNF235 ZNF829 ARID2 RBAK

9.66e-04116130421549307
Pubmed

RhoG signals in parallel with Rac1 and Cdc42.

ARHGEF12 PLD1

1.05e-0313130212376551
Pubmed

Complete physical map and gene content of the human NF1 tumor suppressor region in human and mouse.

OMG SUZ12

1.05e-0313130212696059
Pubmed

Comparison of human chromosome 6p25 with mouse chromosome 13 reveals a greatly expanded ov-serpin gene repertoire in the mouse.

SERPINB3 SERPINB4

1.05e-0313130211863365
InteractionTRIM28 interactions

IPO5 ZNF93 ZNF383 ZNF527 IPO8 ZNF493 ZNF607 ZNF678 ZNF268 ZNF235 ZNF829 ZNF19 ZNF773 ZNF713 BCL11B ZNF37A ZNF792 ZNF780A ZNF587 UTP4 RBAK ZNF256 ZFP1 ZNF264 SUZ12 ZNF30 ZNF107 ZNF417 NUP160 ZNF304 ZNF445

1.71e-09147412731int:TRIM28
InteractionLTBP2 interactions

ZNF607 ZBTB24 RBAK PLD1 ZNF107 ZNF417 SENP5

1.10e-06851277int:LTBP2
InteractionTRIM41 interactions

ZNF784 ZBTB24 ZNF773 ZNF792 ZNF780A ZNF587 RBAK ZFP1 ZNF264 ZNF417

1.52e-0622312710int:TRIM41
InteractionTSGA10 interactions

CEP57L1 ZBTB24 ZNF599 ZNF587 RBAK ZNF417

3.44e-05971276int:TSGA10
CytobandEnsembl 112 genes in cytogenetic band chr19q13

ZNF132 ZNF383 ZNF527 ZNF607 ZNF175 ZNF780B ZNF235 ZNF784 ZNF829 ZNF599 ZNF773 ZNF792 ZNF780A ZNF587 ZNF256 ZNF814 ZNF264 ZNF30 ZNF417 ZNF304

1.86e-10119213020chr19q13
Cytoband18q21.3

SERPINB10 SERPINB3 SERPINB4

3.60e-0611130318q21.3
Cytoband19q13.43

ZNF773 ZNF587 ZNF256 ZNF814 ZNF417

5.17e-0687130519q13.43
Cytoband19q13.4

ZNF132 ZNF175 ZNF264 ZNF304

7.82e-0579130419q13.4
Cytoband19q13.11

ZNF599 ZNF792 ZNF30

2.89e-0445130319q13.11
CytobandEnsembl 112 genes in cytogenetic band chr19p12

ZNF93 ZNF493 ZNF43 ZNF99

4.16e-041221304chr19p12
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF502 ZNF93 ZNF132 ZNF383 ZNF527 ZNF672 ZNF493 ZNF607 ZNF678 ZNF268 ZNF175 ZNF423 ZNF780B BCL11A ZNF235 ZNF784 ZBTB24 ZNF829 ZNF599 ZNF19 ZNF773 ZNF713 BCL11B ZNF37A ZNF792 ZNF780A ZNF43 ZNF587 RBAK ZNF256 ZFP1 ZNF814 ZNF264 SUZ12 ZNF30 ZNF107 ZNF99 ZNF417 ZNF304 ZNF445

1.76e-30718984028
GeneFamilyGlycogen phosphorylases

PYGB PYGL PYGM

1.54e-073983437
GeneFamilySerpin peptidase inhibitors

SERPINB10 SERPINB3 SERPINB4 SERPINB12

4.67e-0537984739
GeneFamilyEMI domain containing

MMRN1 MMRN2

6.00e-047982540
GeneFamilyAnoctamins

ANO4 ANO3

1.27e-0310982865
GeneFamilyArmadillo repeat containing|Importins

IPO5 IPO8

4.20e-0318982596
CoexpressionNAKAYA_PLASMACYTOID_DENDRITIC_CELL_FLUMIST_AGE_18_50YO_7DY_UP

IPO5 INTS1 NDST2 SIDT1 PEX13 BCL11A TUBGCP4 MMRN1 ZNF713 TBC1D4 HIBCH PI4KA SYNE2 PITPNA ZNF814 PYGB TMEM131 TOR1B SUZ12 NUP160

1.82e-06121512820M41122
ToppCellControl-Epithelial_alveolar-AT_2-Differentiating_AT1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADGRG5 TUBGCP4 ZNF784 ZNF829 ESYT3 PKHD1 PYGL

4.06e-0715713074766f7d545bf2d775390589460677519cb92f4d5
ToppCellcellseq2-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-VEC|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

NHSL2 ZNF175 ZNF423 ASAP3 ADAMTS6 PLA2G4B ZNF814

1.41e-061891307bccb3481ffed597c845fe860da658505316105b5
ToppCellPBMC-Control-cDC_8|Control / Compartment, Disease Groups and Clusters

ZNF502 ZNF493 RAB44 FAM83D TOR1B NR1I3

5.91e-061531306db1a6914f2033fb0748e0523cffe5d6dc4e901be
ToppCellAdult-Immune-mast_cell-D175|Adult / Lineage, Cell type, age group and donor

ZNF268 RAB44 TBC1D24 TENM1 ZNF107 RASGRP2

7.36e-0615913069f53fe2e0f25448d62a591c8e528e9a49b5400d5
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

BCL11B TBC1D4 ADAMTS6 SYNE2 ZNF256 TENM1

1.40e-051781306f94e306b9550f3d1b5de0bb806790c17823d439e
ToppCellmoderate-Myeloid-pDC|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

ADGRG5 SIDT1 BCL11A MMRN1 SLC12A3 RASGRP2

1.49e-051801306a0751ad5e42a21cb107d900abfa9ee967a0069fc
ToppCellNS-moderate-d_16-33-Myeloid-pDC|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ADGRG5 SIDT1 BCL11A MMRN1 SLC12A3 RASGRP2

1.49e-051801306144818e69613296cde43f29cb8c20899c670b319
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

BCL11B TBC1D4 ADAMTS6 SYNE2 ZNF256 TENM1

1.74e-051851306f1263899a2d41d182022dc4ca62cbae08a463c89
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

BCL11B TBC1D4 ADAMTS6 SYNE2 ZNF256 TENM1

1.80e-051861306bbcd9062c0f6f65ca6f3cb101b6fa72ddd1e14fe
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Scavenging_endothelial-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

APCDD1 ARHGEF12 ELOVL7 MMRN1 TBC1D4 MMRN2

2.28e-051941306ea5e1bc8d9e27cabfe1fb833ca47ec0893593b12
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Scavenging_endothelial|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

APCDD1 ARHGEF12 ELOVL7 MMRN1 TBC1D4 MMRN2

2.28e-051941306cceb7c88492bb6cd531e1c2651638da1ddf30931
ToppCelldistal-Hematologic-Plasmacytoid_Dendritic-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ADGRG5 SIDT1 BCL11A SLC12A3 PI4KA CYP2U1

2.70e-052001306ef42753c9fbe3770e3f415cd7ab412654d359edb
Drugvinylene

ZNF93 ZNF132 ZNF175 ZNF423 ZNF235 ZBTB24 BCL11B ARID2 RBAK ZNF264 ZNF107 ZNF304 ZNF445

1.47e-0924512913CID000006326
Drug5-n-propylthioadenosine

GAMT PYGB PYGL PYGM

1.46e-0861294CID000656428
Drug3,5-dimethylphenyl isocyanate

PYGB PYGL PYGM

1.78e-0731293CID000521488
Drug5-ethyl-4-hydroxy-2-methyl-3(2H)-furanone

PYGB PYGL PYGM

1.78e-0731293CID000093111
Drugadenosine-5'-chloromethylphosphonate

PYGB PYGL PYGM

1.78e-0731293CID000191554
Drughydan

PYGB PYGL PYGM

1.78e-0731293CID000008360
DrugEHMF

PYGB PYGL PYGM

1.78e-0731293CID000033931
Drug5'-deoxy-5'-fluoro-5'-(methylthio)adenosine

PYGB PYGL PYGM

1.78e-0731293CID000147839
Drugpyridoxal 5'-methylenephosphonate

PYGB PYGL PYGM

1.78e-0731293CID003082249
DrugPlp 5'-mpa

PYGB PYGL PYGM

1.78e-0731293CID003082151
Drugglucose-1,2-cyclic phosphate

PYGB PYGL PYGM

1.78e-0731293CID000191723
Drug3'-FFdUrd

PYGB PYGL PYGM

1.78e-0731293CID000072260
Drug2',3',4',5,5'-pentachloro-2-biphenylol

PYGB PYGL PYGM

1.78e-0731293CID000119518
DrugAC1L8XK3

PYGB PYGL PYGM

1.78e-0731293CID000409735
DrugN-acetyl-N'-beta-D-glucopyranosyl urea

PYGB PYGL PYGM

1.78e-0731293CID000446801
DrugNSC758405

PYGB PYGL PYGM

1.78e-0731293CID000003201
Drug3,5-dinitrophenyl phosphate

PYGB PYGL PYGM

1.78e-0731293CID000151920
Drugriboflavin tetraacetate

PYGB PYGL PYGM

1.78e-0731293CID000094186
Drugpyridoxal phosphoglucose

PYGB PYGL PYGM

1.78e-0731293CID000196007
Drug2,5-dimethyl-3-furanone

PYGB PYGL PYGM

1.78e-0731293CID000085730
Drug3,5-dinitrophenol

PYGB PYGL PYGM

1.78e-0731293CID000011459
Druggalocitabine

PYGB PYGL PYGM

7.08e-0741293CID000065950
Drug2,5-anhydro-D-mannitol 1-phosphate

PYGB PYGL PYGM

7.08e-0741293CID000189134
DrugAC1LAMW2

PYGB PYGL PYGM

7.08e-0741293CID000491364
DrugFdUrd-C8

PYGB PYGL PYGM

7.08e-0741293CID000094262
DrugMem-CC

PYGB PYGL PYGM

7.08e-0741293CID003081269
Drug5-deoxyribose-1-phosphate

PYGB PYGL PYGM

7.08e-0741293CID000135786
Drugingliforib

PYGB PYGL PYGM

7.08e-0741293CID006451325
Druguric acid riboside

PYGB PYGL PYGM

7.08e-0741293CID000164933
Drugpseudo-dl-glucose

PYGB PYGL PYGM

7.08e-0741293CID000125259
DrugBCIp4A

PYGB PYGL PYGM

7.08e-0741293CID000192417
Drugpyridoxal diphosphate

PYGB PYGL PYGM

7.08e-0741293CID000125696
Drug3'-chloromethotrexate

PYGB PYGL PYGM

7.08e-0741293CID000097703
Drugheptulose-2-P

PYGB PYGL PYGM

1.76e-0651293CID000124823
Drugm-anisidine

PYGB PYGL PYGM

1.76e-0651293CID000010824
Drug6-FPLP

PYGB PYGL PYGM

1.76e-0651293CID000146246
Druggluconohydroximo-1,5-lactone

PYGB PYGL PYGM

1.76e-0651293CID009576855
Drug2-hydroxypropylphosphonate

PYGB PYGL PYGM

1.76e-0651293CID000441028
DrugDHPBU

PYGB PYGL PYGM

1.76e-0651293CID000125914
Drug6-FDPL

PYGB PYGL PYGM

1.76e-0651293CID000129578
Drug5'-isobutylthioinosine

PYGB PYGL PYGM

1.76e-0651293CID003080910
Drug3'-O-methylpyridoxal 5'-phosphate

PYGB PYGL PYGM

1.76e-0651293CID003082179
DrugGlcMan

PYGB PYGL PYGM

1.76e-0651293CID000152120
DrugU66985

PYGB PYGL PYGM

1.76e-0651293CID000127224
Drugindirubin-5-sulphonate

PYGB PYGL PYGM

1.76e-0651293CID005288641
DrugAC1O3M08

PYGB PYGL PYGM

1.76e-0651293CID006331955
DrugAC1LCUXJ

PYGB PYGL PYGM

1.76e-0651293CID000656425
Drug6-amino-5-bromouracil

PYGB PYGL PYGM

1.76e-0651293CID000080578
Drugetafenone

PYGB PYGL PYGM

1.76e-0651293CID000003275
DrugddEtUrd

PYGB PYGL PYGM

1.76e-0651293CID000451452
Drug5-trifluoromethyl-2'-deoxycytidine

PYGB PYGL PYGM

1.76e-0651293CID000125618
DrugCV-araU

PYGB PYGL PYGM

3.51e-0661293CID006441877
Drug2-thiothymidine

PYGB PYGL PYGM

3.51e-0661293CID003005944
DrugCarbocyclic Bvdc

PYGB PYGL PYGM

3.51e-0661293CID006438602
DrugDNPP

PYGB PYGL PYGM

3.51e-0661293CID000067056
Drug5-chloro-indole-2-carboxylic acid

PYGB PYGL PYGM

3.51e-0661293CID000082693
Drug2,2-dimethyl-3-hydroxybutyric acid

PYGB PYGL PYGM

3.51e-0661293CID000152984
DrugEdUMP

PYGB PYGL PYGM

3.51e-0661293CID003085112
Drug5'-deoxy-5'-chloroformycin

PYGB PYGL PYGM

3.51e-0661293CID000126430
DrugNSC-97433

PYGB PYGL PYGM

3.51e-0661293CID000001803
DrugAzddCyd

PYGB PYGL PYGM

3.51e-0661293CID000451374
Drug5-Ffdru

PYGB PYGL PYGM

3.51e-0661293CID000065561
DrugAR-L57

PYGB PYGL PYGM

3.51e-0661293CID000156890
DrugCarbocyclic Ivdu

PYGB PYGL PYGM

3.51e-0661293CID006439191
Drugalpha-(fluoromethyl)dehydroornithine

PYGB PYGL PYGM

6.12e-0671293CID006439607
Drug6-fluoropyridoxal

PYGB PYGL PYGM

6.12e-0671293CID003080803
Drug2',3'-dideoxy-3'-fluorocytidine

PYGB PYGL PYGM

6.12e-0671293CID000356019
Drugheptenitol

PYGB PYGL PYGM

6.12e-0671293CID000188267
DrugAC1L3372

PYGB PYGL PYGM

6.12e-0671293CID000108025
Drug1 Gpt

PYGB PYGL PYGM

6.12e-0671293CID000101247
Drugformycins

PYGB PYGL PYGM

6.12e-0671293CID000512867
DrugPromonta

PYGB PYGL PYGM

6.12e-0671293CID000108494
Drug5'-methylthioinosine

PYGB PYGL PYGM

6.12e-0671293CID000161214
Drughydantocidin

PYGB PYGL PYGM

6.12e-0671293CID000125429
DrugBrVarafUTP

PYGB PYGL PYGM SMG6

9.57e-06241294CID005273539
DrugAC1NUVX5

PYGB PYGL PYGM

9.75e-0681293CID005461894
Drug6-methylpurine

PYGB PYGL PYGM

9.75e-0681293CID005287547
Drugamorphin

PYGB PYGL PYGM

9.75e-0681293CID000122792
DrugEtafenone [inn]

PYGB PYGL PYGM

9.75e-0681293CID000066659
Drug6-benzyl-2-thiouracil

PYGB PYGL PYGM

1.46e-0591293CID000685814
Drug5'-methylthiotubercidin

PYGB PYGL PYGM

1.46e-0591293CID000188350
Drugalpha-maltosyl fluoride

PYGB PYGL PYGM

1.46e-0591293CID000194237
Drug5-Iodoribose 1-phosphate

PYGB PYGL PYGM

1.46e-0591293CID003035973
Drug5'-iodo-5'-deoxyadenosine

PYGB PYGL PYGM

1.46e-0591293CID000107502
Drug8-azidoadenosine 5'-monophosphate

PYGB PYGL PYGM

2.07e-05101293CID000124726
Drug2,6-dihydroxypyridine

PYGB PYGL PYGM

2.07e-05101293CID000069371
Drug6-methyluridine

PYGB PYGL PYGM

2.07e-05101293CID000092887
DrugUDP-pyridoxal

PYGB PYGL PYGM

2.07e-05101293CID000126789
Drugglucosyl fluoride

PYGB PYGL PYGM

2.84e-05111293CID000150967
DrugCid 11299980

PYGB PYGL PYGM

2.84e-05111293CID009856533
Drug9 Da

PYGB PYGL PYGM

2.84e-05111293CID005287565
Drug5-(2-chloroethyl)uracil

PYGB PYGL

3.19e-0521292CID010442204
Drug6878P

PYGB PYGL

3.19e-0521292CID002725013
Drug1-N-Acetyl-Beta-D-Glucosamine

PYGL PYGM

3.19e-0521292DB02320
DrugAC1LBRFU

PYGB PYGL

3.19e-0521292CID000562981
DrugBCX-34

PYGB PYGL PYGM

3.77e-05121293CID000060817
DrugAp4U

PYGB PYGL PYGM

3.77e-05121293CID000165888
Drugphenylurethane

PYGB PYGL PYGM

3.77e-05121293CID000007591
Drugacyclothymidine

PYGB PYGL PYGM

3.77e-05121293CID000072358
Drug5'-deoxypyridoxal

PYGB PYGL PYGM

3.77e-05121293CID000164889
Diseasenonsyndromic deafness (is_implicated_in)

TBC1D24 USH2A

1.78e-0521252DOID:0050563 (is_implicated_in)
Diseaseretinitis pigmentosa (implicated_via_orthology)

RPGRIP1 EYS USH2A

2.02e-04271253DOID:10584 (implicated_via_orthology)
DiseaseAbnormality of the skeletal system

INTS1 SUZ12

4.90e-0481252C4021790
DiseaseCiliopathies

RPGRIP1 ZNF423 PKHD1 USH2A

1.25e-031101254C4277690
Diseaseacute graft vs. host disease, donor genotype effect measurement

EYS TMEM131

1.80e-03151252EFO_0004599, EFO_0007892
DiseaseIGA glomerulonephritis

PADI4 DUSP22 GNAO1

1.93e-03581253EFO_0004194
DiseaseCannabis use

IPO8 SMG6

2.05e-03161252EFO_0007585
DiseaseDisorder of eye

RPGRIP1 WFS1 ZNF423 EYS USH2A

2.13e-032121255C0015397
Diseasesphingomyelin 14:0 measurement

THADA SYNE2

2.32e-03171252EFO_0010390
Diseasecortical thickness

ZNF423 SIDT1 ARHGEF12 RAB44 THADA BCL11B PI4KA UTP4 PKHD1 PYGB TMEM131 SMG6

2.76e-03111312512EFO_0004840
Diseasenon-word reading

BCL11B SLC12A3 ZMIZ2

2.92e-03671253EFO_0005299
Diseasediabetes mellitus

ANO4 WFS1 ZFP1

3.04e-03681253EFO_0000400
DiseaseTakayasu arteritis

APCDD1 DUSP22 GNAO1 ABHD16A

3.68e-031481254EFO_1001857
Diseasehematocrit

ZNF383 BCL11A ZNF829 BCL11B TBC1D4 ARID2 ZMIZ2 BEND7 PKHD1 GNAO1 NUP160

3.86e-03101112511EFO_0004348

Protein segments in the cluster

PeptideGeneStartEntry
SDLNKRFILSFLHAH

SMG6

886

Q86US8
SFFVHNVATERLHLK

ESYT3

516

A0FGR9
FLQSLIKFFHAQHNF

ASAP3

211

Q8TDY4
QGLKIHQRFHFASAL

ATP13A1

616

Q9HD20
QLALFLARKHLHNFE

ABHD16A

526

O95870
QRQRFSFITHLQDKH

ARID2

1676

Q68CP9
QRIHHFIIHNKETFF

ANO4

241

Q32M45
FAKHQARAHLFQTSK

ASXL3

1111

Q9C0F0
FHLNLTLNTDFVSKH

ADAMTS6

96

Q9UKP5
HQFFLDRSAHLKVSV

ARHGEF12

426

Q9NZN5
ARIHHFIINNKDTFF

ANO3

286

Q9BYT9
SIHQEFTRTNFHLFI

RBPJL

501

Q9UBG7
KTSFLHLLHQNSFAT

RAB44

846

Q7Z6P3
NFIHKQERRLFTNFH

PITPNA

211

Q00169
SRFNAFKRTNTILHH

HIBCH

11

Q6NVY1
LKLSFHGFNTINHFF

OR5D16

166

Q8NGK9
LFHFHGTLRKLQLQE

NR1I3

246

Q14994
KDFFTNHTLVLHVAR

PADI4

191

Q9UM07
ATHRQKFLFSLSQHI

POC1A

131

Q8NBT0
ASFHVRKKTHIQLQF

EYS

2731

Q5T1H1
HFVHVAEKLLQLQNF

RASGRP2

226

Q7LDG7
HLAAFINKFVQFIHK

INTS1

1951

Q8N201
IHLSINFFSLNKTLH

MMRN1

911

Q13201
QRSLEQHQRLFHSLF

MMRN2

741

Q9H8L6
FKFQSNLVVHRRSHT

BCL11A

386

Q9H165
FLRNHKQEKHLVFFS

DDX55

261

Q8NHQ9
RFLNSPLFHAKHQNT

CSNKA2IP

86

A0A1B0GTH6
LLSHFQSSNKFDHLT

FAM83D

301

Q9H4H8
AVLFSHRKIQFHIFT

GXYLT2

131

A0PJZ3
RHAQFLLVNFNHIHK

PI4KA

966

P42356
HDHFLSNLLAQSFIL

TUBGCP4

561

Q9UGJ1
SNFRFHRFLDVNSHK

TUBGCP5

46

Q96RT8
NQSFHFRIHRQLKNV

PLA2G4B

61

P0C869
RFHHVAQAFLKLLSS

LINC00336

116

Q6ZUF6
ILANEHNVALFKHFA

IPO5

201

O00410
NRFFTLTVIRHHLAF

NBPF3

611

Q9H094
QQRKFSHSTLRHFGL

CYP2U1

176

Q7Z449
STFLHILAKSLSQHF

GRID2IP

1061

A4D2P6
FKFQSNLIVHRRSHT

BCL11B

436

Q9C0K0
LRKKNSQVTFLHVFH

ELOVL7

136

A1L3X0
VHFFHTNFLVSQLIR

DPP9

811

Q86TI2
VLFLTRHFIFHDNNN

APCDD1

306

Q8J025
QNLTRHFKESIKFIH

DUSP22

61

Q9NRW4
THQFNFIKNHAFRLL

GAMT

146

Q14353
DRSFLNLFHLVHAQA

FBXO47

421

Q5MNV8
LSQTSQDFKHHSFLI

BEND7

471

Q8N7W2
NLFQKNSSFHPIRVH

CEP57L1

431

Q8IYX8
ENFHHIFATLSRLKI

EXOC1

731

Q9NV70
LLSHIFHGRKNFFIT

H6PD

461

O95479
FSRHLIFQLHDVAFK

PRIMPOL

166

Q96LW4
LHAFSSLKFHNELNL

IPO8

481

O15397
KLASHHNHFSQIVIF

OR10K2

186

Q6IF99
LQEFVKATQIRFHFH

USH2A

476

O75445
SKKRQLLLFQFAHHL

UTP4

341

Q969X6
FKQHLLQSRHRGAFE

THADA

1096

Q6YHU6
NLFELHIHQAFLTSA

RPGRIP1

626

Q96KN7
RFEHHSNILLTFENK

SYNE2

436

Q8WXH0
NFFTTLRVVHHKFHS

TMEM120A

321

Q9BXJ8
HLEHNQFSKLNLALF

LRRTM3

211

Q86VH5
QFDKHASLRHSLFNT

NHSL2

256

Q5HYW2
DHTKFSFNLENHIIL

NXPE2

41

Q96DL1
FIQKHGTNFLKDHRF

PLD1

326

Q13393
IFQASKHHLIKLSFQ

OVCH2

461

Q7RTZ1
VETHFTFKNLHFRLF

GNAO1

186

P09471
VFKHLNNFLQGKRFH

SETMAR

626

Q53H47
NSNIPLETRHFLFKH

TENM1

251

Q9UKZ4
ENTFNKTHTFHFLLG

NSMCE4A

206

Q9NXX6
VLDVANHFSRLKIHF

PEX13

161

Q92968
NHFSRLKIHFTKVFS

PEX13

166

Q92968
FQVLGQAFHKHLSSL

PKHD1

2206

P08F94
FFQEVARKHIISHLF

NUP160

826

Q12769
VHHQFQKLLTEFNKS

SERPINB3

81

P29508
TNLTHLYLHNNKFTF

OMG

191

P23515
NHPFLFFIRHNKTQT

SERPINB12

381

Q96P63
TVLLHFHFRKQSDSL

ADGRG5

266

Q8IZF4
LFHSALLHFQEVRTK

AQP11

176

Q8NBQ7
FHARNIHQTFQLIFN

CIP2A

226

Q8TCG1
FFSEKLVLHLQQRTH

ZNF37A

251

P17032
SKRQFVHLAVHAENF

TBC1D24

326

Q9ULP9
KAFRLSSFLHAHQRI

ZNF30

351

P17039
TFAQKFELTTHQRIH

ZFP1

276

Q6P2D0
KTFNHKLTFVHHQRI

ZNF132

326

P52740
AFNQFSTLITHKKIH

ZNF93

181

P35789
AFNHFSALRKHQIIH

ZNF99

321

A8MXY4
AFSNFSALRKHEIIH

ZNF99

461

A8MXY4
AFNHFSALRKHQIIH

ZNF99

601

A8MXY4
VFNQFSTLTRHKIIH

ZNF107

336

Q9UII5
DKVHFFNSFFHRQLV

SENP5

601

Q96HI0
KAFTHRSTFIQHNVT

ZNF599

346

Q96NL3
FNKFSNLTQHKRIHT

ZNF678

246

Q5SXM1
AFTQFASLTRHKRIH

ZNF678

301

Q5SXM1
FNKFSSLTQHRRIHT

ZNF678

386

Q5SXM1
FTKSSQLFQHARIHT

ZNF383

291

Q8NA42
AFSFKSQLIIHQRIH

ZNF268

536

Q14587
QAFNFHTKLTRHQRI

ZNF19

336

P17023
FNHVRFLQRLNSTHL

SEMA4G

116

Q9NTN9
TELKKNFNRHLHFTL

PYGM

26

P11217
NFNRHLHFTLVKDRN

PYGM

31

P11217
FNLNSAFIRHRKVHT

RBAK

466

Q9NYW8
LKHFQLRTNVAFHFT

SIDT1

166

Q9NXL6
HLQLTFTGFFHKNDK

SUZ12

156

Q15022
FRQKFCFINHQRVHT

ZNF587

361

Q96SQ5
FFTFNSNLLKHQNVH

ZNF256

611

Q9Y2P7
TFRQSALLFHQARAH

ZNF672

136

Q499Z4
SHFHASFFQNRKILP

TMEM131

151

Q92545
FRQKFCFINHQRVHT

ZNF417

361

Q8TAU3
SFRLNSSLKIHQNIH

ZNF607

401

Q96SK3
SFRFISVLKAHQNIH

ZNF607

541

Q96SK3
SFNRHLHFTLVKDRN

PYGB

31

P11216
FFRAHEHSLLSAQLK

NDST2

171

P52849
SFLKQEGRHLHALAF

SLC12A3

91

P55017
VHHQFQKLLTEFNKS

SERPINB4

81

P48594
AFRLHIQFTRHQKFH

ZNF780A

201

O75290
AFQLHIQLTRHQKFH

ZNF780B

201

Q9Y6R6
KKLQHLFAFLAHTQR

USP38

486

Q8NB14
VFIFEHKAQHISRFI

TBC1D4

116

O60343
AFTKSSQLFLHLRIH

ZNF829

276

Q3KNS6
FRLQHNLAVSNHVFQ

ZMIZ2

436

Q8NF64
FNQFSNLTTHKRIHT

ZNF43

351

P17038
KVFKYNHFLAIHQRS

ZBTB24

301

O43167
KLFSHKSNLFIHQIV

ZNF773

226

Q6PK81
NFVLHNRRHTGEKSF

ZNF264

301

O43296
TFNKSSQLISHKRFH

ZNF445

986

P59923
KFFRHSSVLFRHQKL

ZNF502

526

Q8TBZ5
FFSRSSNLIQHKRVH

ZNF792

346

Q3KQV3
FYRFSNLNTHKIIHT

ZNF493

566

Q6ZR52
HQVLYRHFIQSLSKF

TTC37

201

Q6PGP7
AFSRKDTLVQHQRFH

ZNF304

371

Q9HCX3
KAFRQHSSFTQHLRI

ZNF713

321

Q8N859
FSNFESFQTHLKLHL

ZNF423

641

Q2M1K9
SFNRHLHFTLVKDRN

PYGL

31

P06737
KCFSLSFNLHSHQRV

ZNF235

466

Q14590
NANHPFLFFIRHNKT

SERPINB10

371

P48595
SFSQKSSLIQHQRFH

ZNF814

416

B7Z6K7
AFFQMLSLFRHQRTH

ZNF175

371

Q9Y473
LKSNFVHLFVSTLHF

TOR1B

131

O14657
THHINALIFFFIVSN

WFS1

321

O76024
FSKLLSFHSLFTQHQ

ZNF527

251

Q8NB42
FNNSSNFRKHQRTHF

ZNF784

261

Q8NCA9