Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
MousePhenoabnormal fibroblast physiology

FLNB ING1 CALR NBN RAD54L2 JUND PIK3CB NFKB2 APPL1

2.88e-05271829MP:0020414
MousePhenoabnormal hindlimb bud morphology

MECOM SALL4 TMEM132A

4.12e-0512823MP:0013167
DomainEvi1/Prdm16

MECOM PRDM16

2.95e-0521022IPR030413
PathwayPID_FAS_PATHWAY

PIK3CB MAPK9 MAP2K7 FAIM2

3.23e-0538684M94
Pubmed

Identification and analysis of a novel dimerization domain shared by various members of c-Jun N-terminal kinase (JNK) scaffold proteins.

MAPKBP1 MAPK9 MAP2K7

1.07e-074105323341463
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

TANC2 KMT2B FRYL SBNO2 GAS2L1 JUND GAREM2 NFKB2 TMEM132A ANKRD11 NLGN2 MAPKBP1 PRDM16 ABCC10 WNK2

1.19e-0611051051535748872
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

SPART MECOM NBN AASDH RAD54L2 PIAS2 RBM22 ADO NFKB2 RECQL5 MAPK9

1.74e-065881051138580884
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

TANC2 MAGI1 NES GRK7 PARP8 FRYL CBL MAP4K1 NECTIN2 ANKRD11 MAP2K7 EDRF1 TP53BP2

2.06e-068611051336931259
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

WBP1 ATN1 TMEM61 RAD54L2 MAP4K1 TMEM252 WNK2 TP53BP2 SON

6.55e-06430105935044719
Pubmed

A novel gene, MEL1, mapped to 1p36.3 is highly homologous to the MDS1/EVI1 gene and is transcriptionally activated in t(1;3)(p36;q21)-positive leukemia cells.

MECOM PRDM16

9.03e-062105211050005
Pubmed

Identification of phosphatase that dephosphorylates xylose in the glycosaminoglycan-protein linkage region of proteoglycans.

B3GAT3 PXYLP1

9.03e-062105224425863
Pubmed

High expression of EVI1 and MEL1 is a compelling poor prognostic marker of pediatric AML.

MECOM PRDM16

9.03e-062105225567132
Pubmed

Characterization of pancreatic stem cells derived from adult human pancreas ducts by fluorescence activated cell sorting.

NES PDX1

9.03e-062105216874866
Pubmed

Lnc-HZ08 regulates BPDE-induced trophoblast cell dysfunctions by promoting PI3K ubiquitin degradation and is associated with miscarriage.

CBL PIK3CB

9.03e-062105233864160
Pubmed

Leukemia induction after a single retroviral vector insertion in Evi1 or Prdm16.

MECOM PRDM16

9.03e-062105218496560
Pubmed

Spg20-/- mice reveal multimodal functions for Troyer syndrome protein spartin in lipid droplet maintenance, cytokinesis and BMP signaling.

IST1 SPART

9.03e-062105222619377
Pubmed

Insertional mutagenesis identifies genes that promote the immortalization of primary bone marrow progenitor cells.

MECOM PRDM16

9.03e-062105216109773
Pubmed

Interaction network of human early embryonic transcription factors.

KMT2B ATN1 CALR MECOM RAD54L2 PIAS2 TAF1 PRDM16

1.18e-05351105838297188
Pubmed

Functional proteomics mapping of a human signaling pathway.

FLNB ERCC6 KMT2B SPART PIAS2 CUEDC1 ABRAXAS2 ARHGAP5 TP53BP2 SON

1.26e-055911051015231748
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

MIER2 TANC2 RC3H1 ABRAXAS2 TMEM132A APPL1 NLGN2 PRDM16 CSTF2T

1.94e-05493105915368895
Pubmed

Identification of novel human WW domain-containing proteins by cloning of ligand targets.

MAGI1 WBP1 TP53BP2

2.11e-051810539169421
Pubmed

Nuclear phosphoinositide 3-kinase beta controls double-strand break DNA repair.

NBN PIK3CB

2.70e-053105220368419
Pubmed

JNK is required for effector T-cell function but not for T-cell activation.

MAPK9 MAP2K7

2.70e-053105210811224
Pubmed

The conserved and divergent roles of Prdm3 and Prdm16 in zebrafish and mouse craniofacial development.

MECOM PRDM16

2.70e-053105232044379
Pubmed

Mutations in MAPKBP1 Cause Juvenile or Late-Onset Cilia-Independent Nephronophthisis.

MAPKBP1 MAPK9

2.70e-053105228089251
Pubmed

The oncoprotein EVI1 and the DNA methyltransferase Dnmt3 co-operate in binding and de novo methylation of target DNA.

MECOM DNMT3A

2.70e-053105221695170
Pubmed

EVI1 phosphorylation at S436 regulates interactions with CtBP1 and DNMT3A and promotes self-renewal.

MECOM DNMT3A

2.70e-053105233082307
Pubmed

Hlf marks the developmental pathway for hematopoietic stem cells but not for erythro-myeloid progenitors.

HLF MECOM

2.70e-053105231076455
Pubmed

Prdm3 and Prdm16 cooperatively maintain hematopoiesis and clonogenic potential.

MECOM PRDM16

2.70e-053105232437910
Pubmed

Regulation of the calreticulin gene by GATA6 and Evi-1 transcription factors.

CALR MECOM

2.70e-053105218303859
Pubmed

Correction of X-linked chronic granulomatous disease by gene therapy, augmented by insertional activation of MDS1-EVI1, PRDM16 or SETBP1.

MECOM PRDM16

2.70e-053105216582916
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

FLNB NRCAM APBA1 IST1 RAD54L2 USP9Y PIAS2 CUEDC1 ARHGAP5 RBM22 APPL1 TTC17 TAF1 PIP4P2

3.28e-0512851051435914814
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

FLNB KMT2B USP24 MECOM PIAS2 TAF1 CSTF2T TP53BP2

4.11e-05418105834709266
Pubmed

Genetic variation in healthy oldest-old.

ING1 HSPB2 DNMT3A

5.17e-0524105319680556
Pubmed

A novel dual specificity phosphatase SKRP1 interacts with the MAPK kinase MKK7 and inactivates the JNK MAPK pathway. Implication for the precise regulation of the particular MAPK pathway.

MAPK9 MAP2K7

5.40e-054105211959861
Pubmed

c-Jun can recruit JNK to phosphorylate dimerization partners via specific docking interactions.

JUND MAPK9

5.40e-05410528945519
Pubmed

JNK1 modulates osteoclastogenesis through both c-Jun phosphorylation-dependent and -independent mechanisms.

JUND MAPK9

5.40e-054105212376563
Pubmed

Caspase-mediated cleavage of JNK during stress-induced apoptosis.

MAPK9 MAP2K7

5.40e-054105212821118
Pubmed

SPG20 protein spartin is recruited to midbodies by ESCRT-III protein Ist1 and participates in cytokinesis.

IST1 SPART

5.40e-054105220719964
Pubmed

A vaccinia virus-driven interplay between the MKK4/7-JNK1/2 pathway and cytoskeleton reorganization.

MAPK9 MAP2K7

5.40e-054105222031940
Pubmed

A novel Jun N-terminal kinase (JNK)-binding protein that enhances the activation of JNK by MEK kinase 1 and TGF-beta-activated kinase 1.

MAPKBP1 MAPK9

5.40e-054105210471813
Pubmed

Activation of phosphatidylinositol 3-kinase β by the platelet collagen receptors integrin α2β1 and GPVI: The role of Pyk2 and c-Cbl.

CBL PIK3CB

5.40e-054105225960397
Pubmed

HER2-driven breast cancer suppression by the JNK signaling pathway.

MAPK9 MAP2K7

5.40e-054105236656864
Pubmed

Docking interactions of the JNK scaffold protein WDR62.

MAPK9 MAP2K7

5.40e-054105221749326
Pubmed

Single nucleotide polymorphism array lesions, TET2, DNMT3A, ASXL1 and CBL mutations are present in systemic mastocytosis.

CBL DNMT3A

5.40e-054105222905207
Pubmed

Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.

FLNB KMT2B EFS MAP4K1 WNK2 TP53BP2 FOXJ1

6.55e-05329105717474147
Pubmed

DNMT3L promotes quiescence in postnatal spermatogonial progenitor cells.

SALL4 MAP2K7 DDX4

8.29e-0528105324850856
Pubmed

Expression of the Grb2-related protein of the lymphoid system in B cell subsets enhances B cell antigen receptor signaling through mitogen-activated protein kinase pathways.

CBL MAP4K1

8.97e-055105212496419
Pubmed

Bacterial effector NleL promotes enterohemorrhagic E. coli-induced attaching and effacing lesions by ubiquitylating and inactivating JNK.

MAPK9 MAP2K7

8.97e-055105228753655
Pubmed

Naturally occurring neomorphic PIK3R1 mutations activate the MAPK pathway, dictating therapeutic response to MAPK pathway inhibitors.

MAPK9 MAP2K7

8.97e-055105225284480
Pubmed

Mitogen Kinase Kinase (MKK7) Controls Cytokine Production In Vitro and In Vivo in Mice.

MAPK9 MAP2K7

8.97e-055105234502275
Pubmed

Prdm3 and Prdm16 are H3K9me1 methyltransferases required for mammalian heterochromatin integrity.

MECOM PRDM16

8.97e-055105222939622
Pubmed

Mutations in genes encoding the cadherin receptor-ligand pair DCHS1 and FAT4 disrupt cerebral cortical development.

NES DCHS1

8.97e-055105224056717
Pubmed

Mcidas and GemC1 are key regulators for the generation of multiciliated ependymal cells in the adult neurogenic niche.

MCIDAS FOXJ1

8.97e-055105226395491
Pubmed

PRDM3/16 regulate chromatin accessibility required for NKX2-1 mediated alveolar epithelial differentiation and function.

MECOM PRDM16

8.97e-055105239284798
Pubmed

The stress kinase MKK7 couples oncogenic stress to p53 stability and tumor suppression.

MAPK9 MAP2K7

8.97e-055105221317887
Pubmed

A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.

KMT2B ATN1 IST1 RAD54L2 TAF1 MAPKBP1 CSTF2T WNK2 TP53BP2

9.75e-05608105916713569
Pubmed

Human transcription factor protein interaction networks.

KMT2B ATN1 ING1 RC3H1 MECOM NBN RAD54L2 PIAS2 JUND DGKK NFKB2 RECQL5 TAF1 PRDM16

1.02e-0414291051435140242
Pubmed

SUMOylation stabilizes hSSB1 and enhances the recruitment of NBS1 to DNA damage sites.

NBN PIAS2

1.34e-046105232576812
Pubmed

Nestin is expressed in mesenchymal and not epithelial cells of the developing mouse pancreas.

NES PDX1

1.34e-046105211960711
Pubmed

Thymic epithelial cells co-opt lineage-defining transcription factors to eliminate autoreactive T cells.

SPIB FOXJ1

1.34e-046105235714609
Pubmed

Independent origins of fetal liver haematopoietic stem and progenitor cells.

HLF MECOM

1.34e-046105236104564
Pubmed

ATF4 interacts with Abro1/KIAA0157 scaffold protein and participates in a cytoprotective pathway.

ABRAXAS2 JUND

1.34e-046105222974638
Pubmed

Origin of exocrine pancreatic cells from nestin-positive precursors in developing mouse pancreas.

NES PDX1

1.34e-046105214706696
Pubmed

Atrophin-1, the DRPLA gene product, interacts with two families of WW domain-containing proteins.

MAGI1 ATN1

1.34e-04610529647693
Pubmed

Recruitment of Sprouty1 to immune synapse regulates T cell receptor signaling.

CBL MAP4K1

1.34e-046105219915061
Pubmed

Derepression of sonic hedgehog signaling upon Gpr161 deletion unravels forebrain and ventricular abnormalities.

NES MCIDAS FOXJ1

1.37e-0433105330914320
Pubmed

Discovery and validation of genes driving drug-intake and related behavioral traits in mice.

PARP8 HSPB2 DNMT3A

1.37e-0433105338164795
Pubmed

Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network.

CALR CBL PIAS2 PIK3CB APPL1 MAPK9 MAP2K7

1.38e-04371105725241761
Pubmed

Host PDZ-containing proteins targeted by SARS-CoV-2.

MAGI1 SYNPO2L APBA1

1.63e-0435105333864728
Pubmed

Apolipoprotein E controls ATP-binding cassette transporters in the ischemic brain.

MAPK9 MAP2K7

1.88e-047105220923933
Pubmed

Synergistic activation of stress-activated protein kinase 1/c-Jun N-terminal kinase (SAPK1/JNK) isoforms by mitogen-activated protein kinase kinase 4 (MKK4) and MKK7.

MAPK9 MAP2K7

1.88e-047105211062067
Pubmed

RNA-binding protein L1TD1 interacts with LIN28 via RNA and is required for human embryonic stem cell self-renewal and cancer cell proliferation.

PIAS2 DNMT3A

1.88e-047105222162396
Pubmed

Dynamics of DNA hydroxymethylation and methylation during mouse embryonic and germline development.

DDX4 DNMT3A

1.88e-047105236539615
Pubmed

Phosphorylation-dependent scaffolding role of JSAP1/JIP3 in the ASK1-JNK signaling pathway. A new mode of regulation of the MAP kinase cascade.

MAPK9 MAP2K7

1.88e-047105212189133
Pubmed

JNK and PTEN cooperatively control the development of invasive adenocarcinoma of the prostate.

MAPK9 MAP2K7

1.88e-047105222753496
Pubmed

Maternal epigenetic factors in embryonic and postnatal development.

MECOM PRDM16

1.88e-047105236906847
Pubmed

Genome-wide association study in NSAID-induced acute urticaria/angioedema in Spanish and Han Chinese populations.

ABI3BP HLF

1.88e-047105224236485
Pubmed

WWP2-WWP1 ubiquitin ligase complex coordinated by PPM1G maintains the balance between cellular p73 and ΔNp73 levels.

USP24 SPART ABRAXAS2 RECQL5

2.19e-0497105425071155
Pubmed

An inducible CRISPR/Cas9 screen identifies DTX2 as a transcriptional regulator of human telomerase.

SPART MECOM RAD54L2 PIAS2 NECTIN2

2.23e-04180105535198878
Pubmed

Prdm16 is required for the maintenance of brown adipocyte identity and function in adult mice.

MECOM TFR2 PRDM16

2.26e-0439105324703692
Pubmed

Three-dimensional molecular architecture of mouse organogenesis.

PDX1 MECOM SALL4 DDX4

2.46e-04100105437524711
Pubmed

The CARMA1-Bcl10 signaling complex selectively regulates JNK2 kinase in the T cell receptor-signaling pathway.

MAPK9 MAP2K7

2.50e-048105217189706
Pubmed

The JIP group of mitogen-activated protein kinase scaffold proteins.

MAPK9 MAP2K7

2.50e-048105210490659
Pubmed

CSB interacts with BRCA1 in late S/G2 to promote MRN- and CtIP-mediated DNA end resection.

ERCC6 NBN

2.50e-048105231501894
Pubmed

Selective interaction of JNK protein kinase isoforms with transcription factors.

JUND MAPK9

2.50e-04810528654373
Pubmed

The endonuclease activity of Mili fuels piRNA amplification that silences LINE1 elements.

MOV10L1 DDX4

2.50e-048105222020280
Pubmed

MEKK4 signaling regulates filamin expression and neuronal migration.

NES FLNB

2.50e-048105217145501
Pubmed

Modification of de novo DNA methyltransferase 3a (Dnmt3a) by SUMO-1 modulates its interaction with histone deacetylases (HDACs) and its capacity to repress transcription.

PIAS2 DNMT3A

2.50e-048105214752048
Pubmed

The functional interactome landscape of the human histone deacetylase family.

MIER2 ING1 RBM22 ANKRD11 APPL1 SON

2.53e-04289105623752268
Pubmed

Phospho-tyrosine dependent protein-protein interaction network.

KMT2B MECOM CBL PIK3CB APPL1 CORO6 C6orf141

2.54e-04410105725814554
Pubmed

Upregulation of neurovascular communication through filamin abrogation promotes ectopic periventricular neurogenesis.

NES FLNB FOXJ1

3.02e-0443105327664421
Pubmed

Protein interactome reveals converging molecular pathways among autism disorders.

FLNB ATN1 EFS FRYL RAD54L2 CCBE1 CORO6 MAPKBP1

3.05e-04560105821653829
Pubmed

DNA cross-link repair safeguards genomic stability during premeiotic germ cell development.

ERCC6 DDX4

3.21e-049105231367016
Pubmed

SH3RF3 promotes breast cancer stem-like properties via JNK activation and PTX3 upregulation.

MAPK9 MAP2K7

3.21e-049105232427938
Pubmed

Direct binding of cell polarity protein PAR-3 to cell-cell adhesion molecule nectin at neuroepithelial cells of developing mouse.

NES NECTIN2

3.21e-049105212515806
Pubmed

Interaction of TAGLN and USP1 promotes ZEB1 ubiquitination degradation in UV-induced skin photoaging.

USP24 USP9Y

3.21e-049105237149635
Pubmed

Dual phosphorylation of phosphoinositide 3-kinase adaptor Grb2-associated binder 2 is responsible for superoxide formation synergistically stimulated by Fc gamma and formyl-methionyl-leucyl-phenylalanine receptors in differentiated THP-1 cells.

CBL PIK3CB

3.21e-049105214530346
Pubmed

Fibroblast Growth Factor 21 Mediates Glycemic Regulation by Hepatic JNK.

MAPK9 MAP2K7

3.21e-049105226947074
Pubmed

Homeostatic apoptosis prevents competition-induced atrophy in follicular B cells.

SPIB NFKB2

3.21e-049105234289356
Pubmed

Recruitment of the Mammalian Histone-modifying EMSY Complex to Target Genes Is Regulated by ZNF131.

KMT2B ING1 RBM22 SON

3.54e-04110105426841866
Pubmed

Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.

KMT2B GRK7 RC3H1 USP24 MAP4K1 DGKK CORO6 TAF1 WNK2

3.77e-04730105934857952
Pubmed

Identification of NPM-ALK interacting proteins by tandem mass spectrometry.

PDX1 PIK3CB MAP2K7

3.94e-0447105314968112
Pubmed

Required roles of Bax and JNKs in central and peripheral nervous system death of retinoblastoma-deficient mice.

NES MAPK9

4.00e-0410105217984095
InteractionWWP1 interactions

PRRG1 WBP1 ATN1 SPART CBL CUEDC1 ABRAXAS2 RECQL5 TP53BP2

6.95e-062601029int:WWP1
InteractionITGB3BP interactions

FLNB SUOX RECQL5 ANKRD11 MAPK9

3.01e-05711025int:ITGB3BP
InteractionELK3 interactions

KMT2B MECOM PIAS2 TAF1 MAPK9 PRDM16

3.32e-051201026int:ELK3
InteractionHDAC1 interactions

MIER2 FLNB ERCC6 KMT2B ING1 USP24 PDX1 MECOM SALL4 APPL1 TAF1 MAPK9 PRDM16 CSTF2T TP53BP2 DNMT3A FOXJ1

3.87e-05110810217int:HDAC1
Cytoband19p13.3-p13.2

CALR MAP2K7

4.63e-0414105219p13.3-p13.2
CytobandEnsembl 112 genes in cytogenetic band chr5q11

MCIDAS PARP8 DDX4

1.38e-03951053chr5q11
GeneFamilyZinc fingers C2H2-type|Lysine methyltransferases|PR/SET domain family

KMT2B MECOM PRDM16

2.92e-0434693487
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_1000_k-means-cluster#2

NRCAM FRYL CUEDC1 JUND PIK3CB ZFHX2 PRDM16 WNK2

4.11e-061961008Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_1000_K2
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_2500_k-means-cluster#5

NES NRCAM FRYL AASDH CUEDC1 JUND PIK3CB ZFHX2 PRDM16 WNK2

6.05e-0635010010Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_2500_K5
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_500_k-means-cluster#3

FRYL JUND PIK3CB ZFHX2 PRDM16 WNK2

1.22e-051081006Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_500_K3
CoexpressionAtlasFacebaseRNAseq_e9.5_Mandibular Arch_top-relative-expression-ranked_2500_k-means-cluster#3

MECOM FRYL AASDH CUEDC1 JUND PIK3CB PXYLP1 TAF1 SON

1.76e-053141009Facebase_RNAseq_e9.5_Mandibular Arch_2500_K3
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_500_k-means-cluster#3

NES JUND PIK3CB ZFHX2 PRDM16 WNK2

2.02e-051181006Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_500_K3
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000_k-means-cluster#1

NES NRCAM MECOM FRYL PIK3CB ZFHX2 WNK2

2.07e-051771007Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000_K1
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_500

MAGI1 NES NRCAM MECOM SALL4 FRYL JUND PIK3CB ZFHX2 PRDM16 WNK2

2.20e-0549610011Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_500
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_1000_k-means-cluster#3

NES NRCAM MECOM FRYL JUND PIK3CB ZFHX2 PRDM16 WNK2

3.22e-053391009Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_1000_K3
ToppCellTCGA-Bile_Duct-Primary_Tumor-Cholangiocarcinoma-Intrahepatic|TCGA-Bile_Duct / Sample_Type by Project: Shred V9

TANC2 ATN1 TMEM61 CUEDC1 RBM22 HES4 MAPK9

4.86e-0720010571fa8422fd820d21e285a7e7c4c6fbd8b7277d2af
ToppCellChildren_(3_yrs)-Epithelial-club_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

MAGI1 FLNB MCIDAS MECOM FER1L6 WNK2

4.66e-061821056215c303df42f13597b2c7a95cb157c6bc7aca9a1
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 NRCAM KIZ MECOM HS6ST1 PRDM16

5.44e-061871056f6217d0dd425eac76900b44a4e48f45475f3ac36
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 NRCAM KIZ MECOM HS6ST1 PRDM16

5.61e-061881056e30a4ddac0da8cdcf621d98e28e3895cd9307e7a
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 NRCAM KIZ MECOM HS6ST1 PRDM16

5.96e-06190105611d3c31167ea71809b4cc3757a0c6ea54a448602
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 NRCAM KIZ MECOM HS6ST1 PRDM16

5.96e-061901056b7f8c2bb9459f1d7c1690069dd5a25a81a57cc84
ToppCellCOVID-19-kidney-CD-PC|kidney / Disease (COVID-19 only), tissue and cell type

TANC2 NRCAM KIZ MECOM HS6ST1 PRDM16

6.52e-061931056738689d009e4b118d7ce3171a207294b95cbe78b
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MAGI1 NRCAM MECOM HS6ST1 PXYLP1 PRDM16

6.72e-06194105604bfc555743f7d8821439d05ae442d15e9886c59
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MAGI1 NRCAM MECOM HS6ST1 PRDM16

2.04e-051401055e64f6aa57bc069cfe970089bd1c298433bfaf771
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_4|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SPIB SUOX HS6ST1 NFKB2 DCHS1

2.75e-051491055a85a051e0d82430160967e72fa04b55f43e84513
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_4|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SPIB SUOX HS6ST1 NFKB2 DCHS1

2.84e-0515010557a381f5ae94eba5eb60dcbf83416b4eb18c279ea
ToppCellPBMC-Control-Myeloid-Neutrophil-Neutrophil-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SPART CUEDC1 MOV10L1 NECTIN2 PIP4P2

3.87e-05160105570f3637dd0bcfcef421aa114f946fff0048f192e
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW16-Mesenchymal-Cilia-bearing_cell|GW16 / Sample Type, Dataset, Time_group, and Cell type.

TRAF3IP2 PARP8 APBA1 DERL3 MAP2K7

4.36e-051641055346e1530b4bf30adbcb2f7d64fdfb4cd8df69d7f
ToppCellCerebellum-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Lrg1_(Lrg1)--|Cerebellum / BrainAtlas - Mouse McCarroll V32

TMEM61 SBNO2 C6orf141 DDX4

4.47e-058310543aa95bf2d8ac37e648037faf3d54ebb243a4fde1
ToppCellCerebellum-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Lrg1_(Lrg1)-|Cerebellum / BrainAtlas - Mouse McCarroll V32

TMEM61 SBNO2 C6orf141 DDX4

4.47e-0583105470804dd63221dd5ed26068ec1b50f11875abbc50
ToppCellCerebellum-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Lrg1_(Lrg1)|Cerebellum / BrainAtlas - Mouse McCarroll V32

TMEM61 SBNO2 C6orf141 DDX4

4.47e-05831054c1818411438f53aec76afead5c8caab701b95d39
ToppCellCerebellum-Endothelial-ENDOTHELIAL_STALK-Flt1_2|Cerebellum / BrainAtlas - Mouse McCarroll V32

TMEM61 SBNO2 C6orf141 DDX4

4.47e-058310541e7af8aaa20b4c2a77cf2f330113db0faa9d483c
ToppCellCOVID-19-Myeloid-MoAM5,_CCL3L1|Myeloid / Condition, Lineage and Cell class

NFKB2 MOV10L1 HES4 TP53BP2 FOXJ1

4.88e-051681055ea465152ea31391b63c02425beafa9a4f51f6703
ToppCellB_cells-pDCs|World / Immune cells in Kidney/Urine in Lupus Nephritis

FLNB SPIB CUEDC1 DERL3 RECQL5

4.88e-051681055dc8f94424f60ab56facdcffa969e7f3466ee1b6e
ToppCellCOVID-19-Myeloid-MoAM5,_CCL3L1|COVID-19 / Condition, Lineage and Cell class

JUND NFKB2 MOV10L1 HES4 TP53BP2

5.61e-051731055502f888b7684ed39f5c577eedcacf673ae81d39e
ToppCellNS-moderate-d_07-13-Lymphoid-NK|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

NES NRCAM DCHS1 GPR176 HSPB2

5.93e-051751055f6cd24d22f62469319f9d244e3e5de527d3d4d94
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TMEM61 NRCAM MECOM NRK PRDM16

6.43e-0517810554df6218b20c2f076c22346d23260964cc0d73e65
ToppCellCOVID-19-kidney-AQP1+SLC14A1+EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

MAGI1 FLNB ABI3BP MECOM WNT5B

6.60e-0517910551ce8d18f63e8dd2d3db41fbeca4601bd3b305fba
ToppCellCOVID-19-Heart-EC_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

MAGI1 FLNB MECOM FRYL PRDM16

6.60e-0517910552a53d94f6c30bf887dfe88f1693ea057218c852d
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NRCAM USP24 MECOM NRK PRDM16

6.77e-0518010559e09b3dfe344b5d50520711513d389865d73a861
ToppCelldroplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TANC2 FLNB ABI3BP MECOM DCHS1

7.14e-051821055c7f2d24697affa530b748ab32b1d40bdc1bdc20a
ToppCelldroplet-Lung-21m-Endothelial-arterial_endothelial|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TANC2 FLNB ABI3BP MECOM DCHS1

7.14e-051821055d95635b74e8cd8bc00bfe40340806b59fb9bee43
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

FLNB FER1L6 WNT5B HES4 WNK2

7.14e-0518210553f1a666fe27dd7529c114539ed5f6b8ca585c875
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NRCAM MECOM NRK PRDM16 DNMT3A

7.14e-051821055041bc819e6cf2618bf86bce8dfe2df673f392ba3
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MAGI1 NRCAM MECOM NRK PRDM16

7.32e-05183105531ab55d5f3639f5964541d5eae23044dbda3356e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NRCAM KIZ MECOM HS6ST1 PRDM16

7.32e-051831055d340ab5a77e8d819a1dfb4ca3e9a4b9bc988923c
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRCAM SALL4 CCBE1 NRK DGKK

7.51e-0518410552cbed6462fea2622871bb7e49b0df3d984239281
ToppCellPND14|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NES SPIB HLF JUND NFKB2

7.51e-0518410551bfee4eb121e76a79f48b06b45f05d124fbbedba
ToppCellCOPD-Stromal-Pericyte|COPD / Disease state, Lineage and Cell class

NES NRCAM LRRC53 HES4 HSPB2

7.51e-051841055a56264a22dfc2d3672b20134ab7c3c7c23da5ae1
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRCAM SALL4 CCBE1 NRK DGKK

7.51e-051841055ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRCAM SALL4 CCBE1 NRK DGKK

7.51e-0518410552b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 MAGI1 MECOM HS6ST1 PRDM16

7.71e-0518510553d73b3e0bceb192257e5cfbe64b7ccb379b6e22d
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MAGI1 NRCAM MECOM NRK PRDM16

7.71e-051851055898a093757f86be3e18d2ef1f16a71f50ef81dc3
ToppCelldroplet-Lung-LUNG-1m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TANC2 FLNB MECOM DGKK PRDM16

7.91e-0518610551e67bfb248366d7395efdd2d5e70a97bdb2e68af
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NRCAM USP24 MECOM NRK PRDM16

7.91e-0518610551850583d23903d08226aeb0edb3e07b0994330e4
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NRCAM USP24 MECOM NRK PRDM16

7.91e-0518610554dafc215c42e7949f932a3627359c107943b5d6b
ToppCelldroplet-Lung-1m-Endothelial-arterial_endothelial|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TANC2 FLNB MECOM DGKK PRDM16

7.91e-051861055ffbc78058be8f0dc2e0335cc4c3195a636d17721
ToppCelldroplet-Lung-1m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TANC2 FLNB MECOM DGKK PRDM16

7.91e-051861055ed924852cd7132c8f6703522037dc22bd2c83193
ToppCell(0)_Myeloid-(01)_Dendritic_cell-(011)_pDC|(01)_Dendritic_cell / immune cells in Peripheral Blood (logTPM normalization)

FLNB SPIB CUEDC1 DERL3 RECQL5

8.11e-051871055068502efa3f0ac4cea2fa4a18d1c2f686a4fba54
ToppCellCOVID-19-Heart-EC_2|Heart / Disease (COVID-19 only), tissue and cell type

MAGI1 FLNB MECOM FRYL PRDM16

8.11e-05187105540ffc06a3e3251d9b12da390210d3e045af7537a
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FLNB USP24 MECOM NRK PRDM16

8.11e-051871055f124d2c699b717b7c02a1a70493f515b83dc2f4c
ToppCellLAM-Lymphoid-pDC|Lymphoid / Condition, Lineage and Cell class

FLNB SPIB CUEDC1 DERL3 RECQL5

8.11e-0518710554d9ffd2bbdf1c9869e28991ce9331e4ccf3c0166
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 KIZ MECOM HS6ST1 PRDM16

8.11e-051871055e3095455d2f255854f339f6b05fa87852af0700f
ToppCellCOVID-19-kidney-DCT|kidney / Disease (COVID-19 only), tissue and cell type

HLF USP24 MECOM NRK PRDM16

8.32e-051881055df1fd0819d301679f3c9ea404e942e39095912eb
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDX1 JUND ZFHX2 SON DNMT3A

8.32e-051881055a91443aa8fa8fa87f7501c59219daa0305bd0bbf
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 NRCAM MECOM HS6ST1 PRDM16

8.53e-0518910558ff3c3232eff9de4b5c9b22ecb82bc509d773f58
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MAGI1 NRCAM MECOM HS6ST1 PRDM16

8.53e-051891055a9864873b19ab3e60acf11f288fa7275badc2e42
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HLF USP24 MECOM NRK PRDM16

8.53e-051891055975c0f079903ae36b0ffa54e86294d42ec7697de
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 NRCAM KIZ MECOM HS6ST1

8.53e-051891055bfc76a72b600d641c8fe58346e5d8986c34f3981
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HLF USP24 MECOM NRK PRDM16

8.53e-0518910557eb8f5a951e80f1cfac4d7c9eb169f4eb100c917
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FLNB USP24 MECOM NRK PRDM16

8.53e-051891055e32172ad09e93f6ac6ea2b92145b2b73003f7970
ToppCelldroplet-Lung-1m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TANC2 FLNB MECOM DGKK NECTIN2

8.74e-0519010553b9abc25b17e7295356ded57ff2ca519fa9f2686
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 NRCAM MECOM HS6ST1 PRDM16

8.74e-0519010554836ea19308d2a96694f12ab0653b7ce7b101d2f
ToppCell(0)_Myeloid-(01)_Dendritic_cell|(0)_Myeloid / immune cells in Peripheral Blood (logTPM normalization)

FLNB SPIB ARHGAP5 MAP4K1 DERL3

8.74e-051901055e9507bb0c8ff3d071402731a9b8cfe1bba93fab0
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MAGI1 NRCAM MECOM PXYLP1 PRDM16

8.96e-0519110553e828cffa24ded19f591a7ed6c1fe88ad57fdcac
ToppCellChildren_(3_yrs)-Epithelial-club_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

MAGI1 MECOM HES4 PRDM16 WNK2

8.96e-05191105523776c7302cead3881b39127398f3b3e0d27885e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 NRCAM MECOM HS6ST1 PRDM16

8.96e-05191105596b78b4e819ea6052334bfcbc7abbf35897df885
ToppCelldroplet-Spleen-SPLEEN-1m-Lymphocytic-B_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNB SPIB JUND MAP4K1 NFKB2

9.18e-0519210559b8191e66626919cad2c63349c8ef61e9792fcf5
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 MAGI1 KIZ MECOM PRDM16

9.18e-051921055f7e7491426bbd6ed29a465b58bf67acb93dbb90a
ToppCellCOVID-19-kidney-CNT|kidney / Disease (COVID-19 only), tissue and cell type

NRCAM HLF MECOM HS6ST1 PRDM16

9.18e-051921055d32ae226d95b4b6adb99d14b602be09b661d4cd9
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 NRCAM MECOM HS6ST1 PRDM16

9.18e-051921055fd08ae787e936cfdb1ab8f19b0fd63005b462709
ToppCellhuman_hepatoblastoma-Tumor_cells|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)

MAGI1 FLNB KIZ HLF WNK2

9.41e-051931055503a979328c68b096680b71359a26f02fafdff35
ToppCell390C-Endothelial_cells-Endothelial-B_(Artery)|390C / Donor, Lineage, Cell class and subclass (all cells)

NES FLNB MECOM TMEM132A DCHS1

9.64e-051941055f8a59bd4609d147d8a706bf606e9e8173c9992a3
ToppCell390C-Endothelial_cells-Endothelial-B_(Artery)-|390C / Donor, Lineage, Cell class and subclass (all cells)

NES FLNB MECOM TMEM132A DCHS1

9.64e-05194105504b1acc2e879feafb43f75435281c5acd8d23be2
ToppCellSevere-Treg|Severe / Disease group and Cell class

MAGI1 HLF SUOX PIP4P2 FAIM2

9.64e-0519410557d232d87262ec5f505901345da5113cabf821321
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NRCAM MECOM HS6ST1 PXYLP1 PRDM16

9.64e-05194105569bff17df4a760ccf081cf52ff04af02c14f448d
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-SMC_COL-D|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

WBP1 ABI3BP WNT5B CCBE1 GPR176

9.87e-05195105578cfde21dde4b877fc76c8b0d5ddaabe44b912d7
ToppCellCOVID-19-Lymphoid-Tregs|Lymphoid / Condition, Lineage and Cell class

MAGI1 HLF SUOX PIP4P2 FAIM2

9.87e-0519510559ad844d9d5aac39d133ae8ab9c4839300f08064c
ToppCellfacs-Brain_Myeloid-Hippocampus|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TANC2 CALR HLF USP24 ARHGAP5

9.87e-051951055a1478021a3ed0e779716393124ca2a7770c433b7
ToppCellChildren_(3_yrs)-Epithelial-club_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

MAGI1 MECOM HES4 PRDM16 WNK2

9.87e-051951055dccc32fcf772e2504de7f663ef0a5bd8e23e92fc
ToppCellParenchymal-10x5prime-Stromal-Fibroblastic-Fibro_immune_recruiting|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SPIB ABI3BP EFS MOV10L1 NLGN2

1.01e-041961055614a07334707eafe238d5cb7b080a3ca796a1920
ToppCellCOVID-19-Epithelial-Club,_Basal_cells|Epithelial / Condition, Lineage and Cell class

FER1L6 TMEM132A HES4 WNK2 DNMT3A

1.04e-04197105578ed2810e5a765327e7a6da0ca5d4854bf7a0b6f
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

EFS FER1L6 WNT5B HES4 WNK2

1.04e-041971055107cb153ea7fc74bbd244dbb9d0499c0a8506724
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_secretory|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FLNB APBA1 MECOM FER1L6 WNK2

1.06e-041981055af399569c718f5fd971d73a7926768c9311002a3
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Club|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MAGI1 FLNB APBA1 MECOM WNK2

1.06e-0419810551408e02e053ad3406229bfe8189da03be6366e81
ToppCellParenchymal-NucSeq-Epithelial-Epi_submucosal-gland|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FLNB MCIDAS WNT5B HES4 WNK2

1.06e-041981055fab3135f03cf23a9f04f0eed543a9dc181f39f5f
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

PARP8 USP24 FRYL USP9Y ANKRD11

1.09e-041991055f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCelldistal-2-Endothelial-Artery|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FLNB ABI3BP MECOM HS6ST1 HES4

1.09e-041991055fa8aaf7a90699e41a7a4cee5614f8c9248110327
ToppCelldistal-Endothelial-Artery-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FLNB ABI3BP MECOM HS6ST1 HES4

1.09e-0419910553788f3218356aaaa10684e48d63757037f8a3a3c
ToppCellParenchymal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Duct|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FLNB MCIDAS WNT5B HES4 WNK2

1.11e-042001055b992eeddee38e6fe3564e9b1850f6b20b89bf47d
ToppCellBrain_organoid-organoid_Tanaka_cellReport-5w-Neuronal-Intermediate|5w / Sample Type, Dataset, Time_group, and Cell type.

TANC2 ATN1 JUND NLGN2 WNK2

1.11e-042001055c92e4fc0442404481fcac623d691dae6215b852d
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Neuronal-Intermediate|GW19 / Sample Type, Dataset, Time_group, and Cell type.

NRCAM MAP4K1 PRDM16 MAP2K7

1.87e-041201054eb5b88c47dd4a6f9b55ace24f19d4e81d4ed31e1
ToppCellControl-B_memory-6|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

SCRT2 FLNB NRCAM DGKK

2.12e-0412410543e987915026f503e8d072a837b6e7a34252e5c63
ToppCellThalamus-Endothelial-MURAL-M1(Rgs5Acta2)|Thalamus / BrainAtlas - Mouse McCarroll V32

SYNPO2L WNT5B C6orf141 HSPB2

2.25e-041261054333f83f9ba64d46f22fee328d0a691fd5818bdac
ToppCellThalamus-Endothelial-MURAL|Thalamus / BrainAtlas - Mouse McCarroll V32

SYNPO2L WNT5B C6orf141 HSPB2

2.25e-041261054cf571f36761da3540fb445de89d555cbce8a47ab
DrugDantrolene sodium salt [14663-23-1]; Down 200; 11.8uM; PC3; HT_HG-U133A

ATN1 ING1 CALR HLF GAS2L1 JUND NFKB2 RECQL5 MAP2K7

2.18e-0719310294343_DN
DrugSpiramycin [8025-81-8]; Up 200; 4.8uM; MCF7; HT_HG-U133A

ATN1 SPIB FKRP HLF TFR2 GAS2L1 NFKB2 MAP2K7

2.76e-0619510283844_UP
DrugDiethylstilbestrol [56-53-1]; Down 200; 15uM; MCF7; HT_HG-U133A

MIER2 FKRP NFKB2 RECQL5 TAF1 MAP2K7 GPR176 DNMT3A

3.10e-0619810283895_DN
DrugDapsone [80-08-0]; Up 200; 16.2uM; MCF7; HT_HG-U133A

TANC2 ERCC6 ATN1 ING1 SPART PIK3CB SON DNMT3A

3.21e-0619910281705_UP
Drug5252917; Up 200; 14uM; MCF7; HT_HG-U133A_EA

MAGI1 ABI3BP RAD54L2 JUND NFKB2 MAPKBP1 DNMT3A

2.01e-051851027944_UP
DrugSerotonin hydrochloride [153-98-0]; Up 200; 18.8uM; MCF7; HT_HG-U133A

ATN1 MECOM USP9Y CBL CUEDC1 PIK3CB PRDM16

2.64e-0519310275268_UP
Drug2-Chloropyrazine [14508-49-7]; Down 200; 35uM; MCF7; HT_HG-U133A

NRCAM ABI3BP ING1 SPART RAD54L2 JUND GPR176

2.73e-0519410273570_DN
DrugIndapamide [26807-65-8]; Down 200; 10.6uM; PC3; HT_HG-U133A

ATN1 ING1 CALR SBNO2 GAS2L1 JUND RECQL5

2.73e-0519410274335_DN
Drugwortmannin; Down 200; 0.01uM; MCF7; HT_HG-U133A_EA

NES KMT2B ATN1 PIAS2 B3GAT3 CUEDC1 MAPKBP1

2.82e-051951027911_DN
DrugNeostigmine bromide [114-80-7]; Up 200; 13.2uM; MCF7; HT_HG-U133A

TRAF3IP2 PRRG1 KMT2B ING1 RAD54L2 CBL CSTF2T

2.82e-0519510273294_UP
DrugHomatropine hydrobromide (R,S) [51-56-9]; Up 200; 11.2uM; MCF7; HT_HG-U133A

TANC2 MAGI1 ING1 CALR JUND PIK3CB RECQL5

2.91e-0519610271684_UP
DrugEthacrynic acid [58-54-8]; Up 200; 13.2uM; PC3; HT_HG-U133A

NRCAM SPIB ING1 FKRP MECOM TFR2 WNT5B

2.91e-0519610275742_UP
DrugTalampicillin hydrochloride [39878-70-1]; Up 200; 7.8uM; MCF7; HT_HG-U133A

DOHH ERCC6 CBL TFR2 DCHS1 ZFHX2 TTC17

3.01e-0519710277014_UP
DrugSolasodine [126-17-0]; Up 200; 9.6uM; PC3; HT_HG-U133A

ATN1 FKRP CALR PIAS2 JUND RECQL5 MAP2K7

3.01e-0519710274305_UP
DrugOndansetron Hydrochloride [103639-04-9]; Down 200; 12.2uM; MCF7; HT_HG-U133A

RAD54L2 CUEDC1 TAF1 MAPKBP1 GPR176 ABCC10 DNMT3A

3.01e-0519710273575_DN
Drug(cis-) Nanophine [5072-45-7]; Up 200; 26.8uM; PC3; HT_HG-U133A

MAGI1 DOHH SBNO2 JUND NFKB2 MAP2K7 DNMT3A

3.21e-0519910274543_UP
Drug(cis-) Nanophine [5072-45-7]; Up 200; 26.8uM; PC3; HT_HG-U133A

KMT2B ATN1 NRCAM APBA1 TFR2 DCHS1 FAIM2

3.21e-0519910273806_UP
DrugPropranolol hydrochloride [318-98-9]; Down 200; 13.6uM; HL60; HT_HG-U133A

TANC2 TRAF3IP2 ERCC6 ATN1 PDX1 MAP4K1 MAP2K7

3.21e-0519910273059_DN
DrugKetorolac tromethamine [74103-07-4]; Down 200; 10.6uM; MCF7; HT_HG-U133A

SPART PIAS2 RECQL5 MAPKBP1 EDRF1 CSTF2T DNMT3A

3.21e-0519910275988_DN
DrugCyclopentolate hydrochloride [5870-29-1]; Down 200; 12.2uM; MCF7; HT_HG-U133A

MIER2 ING1 CUEDC1 GAS2L1 JUND ADO TMEM132A

3.21e-0519910276214_DN
DrugPalmatine chloride [3486-67-7]; Down 200; 10.4uM; HL60; HT_HG-U133A

TRAF3IP2 RAD54L2 PIAS2 TFR2 GAS2L1 JUND RECQL5

3.32e-0520010272138_DN
DrugSertaconazole nitrate [99592-39-9]; Up 200; 8uM; HL60; HT_HG-U133A

NRCAM TFR2 GAS2L1 MAP4K1 RECQL5 FAIM2 DNMT3A

3.32e-0520010276128_UP
Diseasemyeloid neoplasm (is_implicated_in)

MECOM CBL

2.36e-0471002DOID:0070004 (is_implicated_in)
DiseaseGrowth Disorders

ERCC6 CBL DNMT3A

2.49e-04361003C0018273
DiseaseMalignant neoplasm of breast

PRRG1 FLNB ERCC6 NRCAM MECOM NBN PIK3CB NECTIN2 APPL1 MAP2K7 TP53BP2 DNMT3A

2.81e-04107410012C0006142
DiseaseLeukemia, Myelocytic, Acute

MECOM CBL GAS2L1 NECTIN2 DNMT3A

3.14e-041731005C0023467
Diseaselung cancer (is_marker_for)

ERCC6 CALR DNMT3A

3.16e-04391003DOID:1324 (is_marker_for)
DiseaseAdenocarcinoma of large intestine

NRK TAF1 MAPK9 MAP2K7

3.25e-04961004C1319315
DiseaseAdenoid Cystic Carcinoma

MIER2 MAGI1 WNT5B SON

3.79e-041001004C0010606
Diseaseurticaria, response to non-steroidal anti-inflammatory, angioedema

ABI3BP HLF

4.03e-0491002EFO_0005531, EFO_0005532, EFO_0005533
DiseaseMalignant neoplasm of salivary gland

MIER2 WNT5B SON

4.83e-04451003C0220636
DiseaseFacies

CCBE1 DNMT3A

5.03e-04101002C0282631
DiseasePeripheral T-Cell Lymphoma

NECTIN2 DNMT3A

5.03e-04101002C0079774
DiseaseSalivary Gland Neoplasms

MIER2 WNT5B SON

5.50e-04471003C0036095
Diseaseacute myeloid leukemia (is_marker_for)

CALR TFR2 DNMT3A

6.21e-04491003DOID:9119 (is_marker_for)
DiseaseHematologic Neoplasms

CALR CBL

7.34e-04121002C0376545
DiseaseMyeloproliferative disease

CALR MECOM

7.34e-04121002C0027022
DiseaseMetastatic melanoma

GRK7 MAP4K1 TAF1

8.26e-04541003C0278883
DiseaseAcute Myeloid Leukemia, M1

MECOM GAS2L1 NECTIN2 DNMT3A

8.79e-041251004C0026998
DiseaseAcute Myeloid Leukemia (AML-M2)

MECOM GAS2L1 NECTIN2 DNMT3A

8.79e-041251004C1879321
DiseaseMaturity onset diabetes mellitus in young

PDX1 APPL1

1.01e-03141002C0342276
DiseaseMYELODYSPLASTIC SYNDROME

CALR MECOM CBL

1.55e-03671003C3463824
Diseasejoint damage measurement

ABI3BP PARP8 MECOM

1.61e-03681003EFO_0005413
DiseaseJuvenile Myelomonocytic Leukemia

CBL DNMT3A

1.87e-03191002C0349639
DiseaseCraniofacial Abnormalities

ERCC6 SALL4 B3GAT3 DNMT3A

1.99e-031561004C0376634
Diseasecolorectal cancer (is_marker_for)

ERCC6 CALR CBL PIK3CB

2.04e-031571004DOID:9256 (is_marker_for)
Diseasegastric ulcer

PDX1 MECOM

2.29e-03211002EFO_0009454
Diseasehyperglycemia (biomarker_via_orthology)

PDX1 CBL

2.29e-03211002DOID:4195 (biomarker_via_orthology)
DiseaseBreast Carcinoma

NRCAM MECOM PIK3CB NECTIN2 MAP2K7 TP53BP2 DNMT3A

2.40e-035381007C0678222
Diseaseotitis media (implicated_via_orthology)

MECOM SALL4

2.51e-03221002DOID:10754 (implicated_via_orthology)
DiseaseGranulomatous Slack Skin

NFKB2 DNMT3A

2.51e-03221002C0376407
DiseaseLymphoma, T-Cell, Cutaneous

NFKB2 DNMT3A

2.75e-03231002C0079773
DiseaseDystonia

ERCC6 KMT2B SUOX

3.15e-03861003C0013421
Diseaseblood tin measurement

ABI3BP NBN

3.24e-03251002EFO_0021530

Protein segments in the cluster

PeptideGeneStartEntry
AQPPEPEALPTIYVV

B3GAT3

66

O94766
LGDAEASDPPPPYSD

ABRAXAS2

296

Q15018
AAIIPPEPSYLEPLD

ANKRD11

1921

Q6UB99
PEPSYLEPLDEGPFS

ANKRD11

1926

Q6UB99
YIPPPPPEDEDSIFA

DDX4

246

Q9NQI0
VEPEAAAYAPPPPAK

DNMT3A

441

Q9Y6K1
PAAFLDILAPPYDPD

ADO

201

Q96SZ5
AEEYETPESPVPPAR

ATN1

731

P54259
VPAAYVPIEPDSPPS

AASDH

81

Q4L235
DYAAPIPTVPLEFLP

RAD54L2

146

Q9Y4B4
APAEDPNYLPLPEEQ

DERL3

211

Q96Q80
AGPYLSVDPAPPAEE

DOHH

141

Q9BU89
SDMPAPSPGLDYEPE

TP53BP2

821

Q13625
IPPAAVPSYVPESRE

RC3H1

696

Q5TC82
PPPPAAEEEASANYF

RBM22

336

Q9NW64
APIYIPDDIPIPAEF

MECOM

66

Q03112
PSYAPKDDSPDEVPS

ERCC6

546

P0DP91
ITVWYDPAEAEAPPP

MAPK9

321

P45984
DPAEAEAPPPQIYDA

MAPK9

326

P45984
YSPDPPAEPSTVLEL

ABCC10

586

Q5T3U5
PVPAYSVEVPEDVPA

DCHS1

1856

Q96JQ0
ELYTEPTPEPATEPA

DGKK

76

Q5KSL6
VIFEPYPSVVDPNDP

PARP8

576

Q8N3A8
KEAPAVPSAPPSYEE

FAIM2

26

Q9BWQ8
ADPSYPVVPESTGPE

MOV10L1

1191

Q9BXT6
YPLPFDPDDPNTSLV

MAGI1

556

Q96QZ7
YISLLPAPPDPEEEE

HSPB2

161

Q16082
PAAPVEPETFPDKYS

GPR176

436

Q14439
APVYDVPNPPFDLEL

NRCAM

641

Q92823
PAADPSTPIPLKYED

EDRF1

626

Q3B7T1
EAENSAPKPVLYPPS

LRRC53

1221

A6NM62
VASDPLYVPDPDPTK

APPL1

256

Q9UKG1
ELAPAAAAPEAPVYA

JUND

181

P17535
IPESPYLVPVIAPSD

FLNB

2271

O75369
SPPDISPYEVPPLAD

PDX1

61

P52945
SPYEVPPLADDPAVA

PDX1

66

P52945
PPDPTKPDYDIRADV

MAP2K7

291

O14733
DSSDEEPPPVYSPPA

CUEDC1

121

Q9NWM3
PEPLAPESYPESVCE

FRYL

2606

O94915
EEDVPPVLVSPSPTY

NES

1211

P48681
APPPYKAPRLDEDGE

KMT2B

2291

Q9UMN6
PDTIQVPVGYEPDPA

HLF

166

Q16534
ASPPVSPIPVSEYCE

KIZ

316

Q2M2Z5
PDDLDLFPTPDPHYE

HS6ST1

51

O60243
PVSVYEDPPDAEPTA

MCIDAS

56

D6RGH6
PNIYPKDPDIDTDPL

FADS2B

261

A8MWK0
GSREPSPVPPDYEDE

HCRTR1

16

O43613
ALDLPVEPNEHYDPP

CEFIP

426

Q711Q0
APPRDAADPPKYVLV

C6orf141

146

Q5SZD1
DPARAPDPPAPDSAY

GAS2L1

546

Q99501
LSEEGYPFPTAPPVD

FRRS1L

76

Q9P0K9
EEFPLPQEFPSYPEA

CCBE1

366

Q6UXH8
HPEIDNPEYSPDPSI

CALR

291

P27797
APPPDDVDYATNPHV

FOXJ1

106

Q92949
PTYVEVPGPCDPEDL

APBA1

441

Q02410
DLYPDTPGPEPALEA

CORO6

361

Q6QEF8
PGEDDAPYDVPLTPK

EFS

181

O43281
PAAPAEAPAPEVYAG

HES4

161

Q9HCC6
EPAPIEDGIVYPEPS

MAPKBP1

946

O60336
PQIPATPPSYESVDD

IST1

271

P53990
DDGYDVPKPPVPAVL

CBL

771

P22681
PAAPIIDSPYGDPID

CSTF2T

106

Q9H0L4
IDSPYGDPIDPEDAP

CSTF2T

111

Q9H0L4
AQPVVVAADTLPYPP

FKRP

76

Q9H9S5
LIEPPFVPDPSVVYA

GRK7

466

Q8WTQ7
PYALSVPDPIDEPSL

SALL4

456

Q9UJQ4
DPAEALRPACPPDYT

NLGN2

756

Q8NFZ4
DPASYQPAVTAPEPD

MIER2

451

Q8N344
DPAAIPPSLTDYSVP

PIAS2

521

O75928
GPDPSLVYRPDVDPE

MIOX

6

Q9UGB7
PSECVLYPLPPSADD

NPIPA7

266

E9PJI5
PSECVLYPLPPSADD

NPIPA8

266

P0DM63
YDDVDIPTPAEDTPP

MAP4K1

381

Q92918
TPAPVIQPPEEDGDY

NRK

906

Q7Z2Y5
YVDVEPPPTVVPDSA

FER1L6

1136

Q2WGJ9
AAPEPAAPPAEIPYE

GAREM2

416

Q75VX8
TPPGAPPDEVYLSDS

SYNPO2L

166

Q9H987
PPDEVYLSDSPAEPA

SYNPO2L

171

Q9H987
LAPAEPAYPPAAPEE

SCRT2

66

Q9NQ03
PADPPQYQEVPLDEA

TMEM132A

241

Q24JP5
PQIESFYPPLDEPSI

NBN

191

O60934
YAPPPPPEQCLSDDE

TAF1

296

P21675
ASPADLPIDPNEPTY

ING1

341

Q9UK53
PVYIPEDIPIPADFE

PRDM16

71

Q9HAZ2
AELPPPYTAIASPDA

PIP4P2

36

Q8N4L2
AFEPDYAVPPLPVSE

TANC2

56

Q9HCD6
VLDLTYSPPAEAFPP

SBNO2

1256

Q9Y2G9
PVTEPPVTDPVYEAL

PXYLP1

51

Q8TE99
SDDDTEAPPPYSPIG

ARHGAP5

981

Q13017
YPPEHEPSIPENLED

PIK3CB

176

P42338
APYPSPVLSEEEDLP

SPIB

121

Q01892
PIPEYSPEEESEPPA

TRAF3IP2

31

O43734
QARFSPYPIPAVEPD

C11orf71

86

Q6IPW1
AEPPEPNEYDIPPAS

RECQL5

631

O94762
TPPAYPTEEALEPSG

TMEM61

146

Q8N0U2
CPAEAPPAYTPQAAE

SPART

166

Q8N0X7
RHYSPEDEPSPEAQP

nan

291

Q6ZSR9
SKCYDLAPAPEAPPA

ZFHX2

2186

Q9C0A1
TQPTPEDLVYVDPSP

WNT5B

271

Q9H1J7
LPVATVDRPDFYPPA

TMEM252

86

Q8N6L7
PDEHEPSPSEDAPLY

USP9Y

2486

O00507
PEDYIDTESPVPPDP

TTC17

141

Q96AE7
TEPHLDPPPEYEDIV

PRRG1

186

O14668
PDPALTKEFDYLPPV

USP24

1666

Q9UPU5
AEPPPELLTENYITP

SUOX

196

P51687
APPDVYLDEAPSSPD

WNK2

1806

Q9Y3S1
PYPEVSQSEPAPLET

ABI3BP

586

Q7Z7G0
LIYPEPADFSQDPPK

TFR2

296

Q9UP52
EDYSPCALPPESVPQ

WBP1

241

Q96G27
VPEPPVVAEPDYVTI

SON

1391

P18583
EPKEPAPETADGPYL

NFKB2

26

Q00653
EDEDLEGPPSYKPPT

NECTIN2

396

Q92692