Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionDNA secondary structure binding

RAD51AP1 WRN SMC5 MECP2

3.56e-0641514GO:0000217
GeneOntologyMolecularFunctionD-loop DNA binding

RAD51AP1 WRN

9.53e-056512GO:0062037
GeneOntologyMolecularFunctionmicrotubule binding

MAPRE1 HAUS8 MTUS1 MAP4 APC TOGARAM1

1.29e-04308516GO:0008017
GeneOntologyMolecularFunctionprotein kinase C binding

SRSF2 TIRAP TOP2A

6.41e-0466513GO:0005080
GeneOntologyMolecularFunctiontubulin binding

MAPRE1 HAUS8 MTUS1 MAP4 APC TOGARAM1

7.46e-04428516GO:0015631
GeneOntologyMolecularFunctionfour-way junction DNA binding

WRN MECP2

1.06e-0319512GO:0000400
GeneOntologyMolecularFunctionmicrotubule plus-end binding

MAPRE1 APC

1.43e-0322512GO:0051010
GeneOntologyMolecularFunctionoutward rectifier potassium channel activity

KCNA2 KCNQ1

2.16e-0327512GO:0015271
GeneOntologyMolecularFunctionscavenger receptor activity

SCARF2 PRG4

2.16e-0327512GO:0005044
GeneOntologyMolecularFunctiondelayed rectifier potassium channel activity

KCNA2 KCNQ1

2.32e-0328512GO:0005251
GeneOntologyMolecularFunctionchromatin binding

NCOR1 MTA3 WRN NUP98 NUCKS1 MECP2 TOP2A

2.59e-03739517GO:0003682
GeneOntologyMolecularFunctiontranscription corepressor activity

NCOR1 SRSF2 MTA3 MECP2

2.76e-03229514GO:0003714
GeneOntologyMolecularFunctiontranscription coregulator activity

NCOR1 SRSF2 MTA3 NUP98 NUCKS1 MECP2

2.98e-03562516GO:0003712
GeneOntologyMolecularFunctionnuclear thyroid hormone receptor binding

NCOR1 TRIP12

3.41e-0334512GO:0046966
GeneOntologyMolecularFunctionATP-dependent activity, acting on DNA

WAPL WRN TOP2A

4.19e-03127513GO:0008094
GeneOntologyMolecularFunctionsingle-stranded DNA binding

RAD51AP1 NUCKS1 SMC5

4.86e-03134513GO:0003697
GeneOntologyMolecularFunctionmolecular condensate scaffold activity

NUP98 MECP2

5.16e-0342512GO:0140693
GeneOntologyBiologicalProcesscell cycle process

MAPRE1 HAUS8 RAD51AP1 NCOR1 WAPL MTA3 MAP4 WRN APC WEE2 TACC2 GPNMB SMC5 INTS3 TOP2A RAB11FIP3

3.71e-0714415316GO:0022402
GeneOntologyBiologicalProcessmicrotubule polymerization

MAPRE1 HAUS8 MAP4 APC TOGARAM1 MECP2

5.41e-07117536GO:0046785
GeneOntologyBiologicalProcessregulation of microtubule polymerization

MAPRE1 HAUS8 APC TOGARAM1 MECP2

9.16e-0769535GO:0031113
GeneOntologyBiologicalProcesspositive regulation of microtubule polymerization

MAPRE1 APC TOGARAM1 MECP2

2.41e-0637534GO:0031116
GeneOntologyBiologicalProcesspositive regulation of microtubule polymerization or depolymerization

MAPRE1 APC TOGARAM1 MECP2

4.04e-0642534GO:0031112
GeneOntologyBiologicalProcessmicrotubule polymerization or depolymerization

MAPRE1 HAUS8 MAP4 APC TOGARAM1 MECP2

4.46e-06168536GO:0031109
GeneOntologyBiologicalProcesspositive regulation of protein polymerization

MAPRE1 CDC42EP4 APC TOGARAM1 MECP2

6.37e-06102535GO:0032273
GeneOntologyBiologicalProcessregulation of microtubule polymerization or depolymerization

MAPRE1 HAUS8 APC TOGARAM1 MECP2

8.42e-06108535GO:0031110
GeneOntologyBiologicalProcessprotein polymerization

MAPRE1 HAUS8 CDC42EP4 MAP4 APC TOGARAM1 MECP2

2.23e-05334537GO:0051258
GeneOntologyBiologicalProcesspositive regulation of protein-containing complex assembly

MAPRE1 CDC42EP4 TIRAP APC TOGARAM1 MECP2

2.48e-05227536GO:0031334
GeneOntologyBiologicalProcessregulation of organelle organization

MAPRE1 HAUS8 RAD51AP1 WAPL CDC42EP4 MAP4 APC TOGARAM1 WEE2 SMC5 MECP2 TOP2A RAB11FIP3

2.56e-0513425313GO:0033043
GeneOntologyBiologicalProcessregulation of protein polymerization

MAPRE1 HAUS8 CDC42EP4 APC TOGARAM1 MECP2

2.73e-05231536GO:0032271
GeneOntologyBiologicalProcessresponse to ionizing radiation

RAD51AP1 WRN NUCKS1 INTS3 MECP2

4.25e-05151535GO:0010212
GeneOntologyBiologicalProcessmitotic cell cycle

MAPRE1 WAPL MTA3 MAP4 APC WEE2 TACC2 GPNMB SMC5 INTS3 RAB11FIP3

4.37e-0510145311GO:0000278
GeneOntologyBiologicalProcessnon-motile cilium assembly

MAPRE1 MAP4 KCNQ1 TOGARAM1

4.81e-0578534GO:1905515
GeneOntologyBiologicalProcessmitotic cell cycle process

MAPRE1 WAPL MTA3 MAP4 APC TACC2 GPNMB SMC5 INTS3 RAB11FIP3

5.43e-058545310GO:1903047
GeneOntologyBiologicalProcessmicrotubule-based process

CFAP47 MAPRE1 HAUS8 NCOR1 MAP4 AP3B2 APC TOGARAM1 TACC2 BSN MECP2

6.42e-0510585311GO:0007017
GeneOntologyBiologicalProcessmicrotubule cytoskeleton organization

CFAP47 MAPRE1 HAUS8 NCOR1 MAP4 APC TOGARAM1 TACC2 MECP2

8.19e-05720539GO:0000226
GeneOntologyBiologicalProcessregulation of microtubule cytoskeleton organization

MAPRE1 HAUS8 APC TOGARAM1 MECP2

8.80e-05176535GO:0070507
GeneOntologyBiologicalProcesspositive regulation of organelle organization

MAPRE1 RAD51AP1 CDC42EP4 APC TOGARAM1 SMC5 MECP2 RAB11FIP3

1.01e-04574538GO:0010638
GeneOntologyBiologicalProcessregulation of microtubule-based process

MAPRE1 HAUS8 APC TOGARAM1 TACC2 MECP2

1.02e-04293536GO:0032886
GeneOntologyBiologicalProcessdouble-strand break repair via homologous recombination

RAD51AP1 WRN NUCKS1 SMC5 INTS3

1.20e-04188535GO:0000724
GeneOntologyBiologicalProcessprotein localization to centrosome

MAPRE1 APC RAB11FIP3

1.27e-0438533GO:0071539
GeneOntologyBiologicalProcessprotein localization to microtubule organizing center

MAPRE1 APC RAB11FIP3

1.37e-0439533GO:1905508
GeneOntologyBiologicalProcessrecombinational repair

RAD51AP1 WRN NUCKS1 SMC5 INTS3

1.39e-04194535GO:0000725
GeneOntologyBiologicalProcesspositive regulation of supramolecular fiber organization

MAPRE1 CDC42EP4 APC TOGARAM1 MECP2

1.46e-04196535GO:1902905
GeneOntologyBiologicalProcesschromosome segregation

MAPRE1 HAUS8 NCOR1 WAPL APC SMC5 TOP2A

1.78e-04465537GO:0007059
GeneOntologyBiologicalProcesspositive regulation of cytoskeleton organization

MAPRE1 CDC42EP4 APC TOGARAM1 MECP2

1.80e-04205535GO:0051495
GeneOntologyBiologicalProcessregulation of protein-containing complex assembly

MAPRE1 HAUS8 CDC42EP4 TIRAP APC TOGARAM1 MECP2

2.42e-04489537GO:0043254
GeneOntologyBiologicalProcessspindle organization

MAPRE1 HAUS8 NCOR1 MAP4 TACC2

2.71e-04224535GO:0007051
GeneOntologyBiologicalProcessregulation of cell cycle process

RAD51AP1 WAPL MTA3 APC WEE2 GPNMB SMC5 INTS3 RAB11FIP3

2.73e-04845539GO:0010564
GeneOntologyBiologicalProcessinositol metabolic process

PPIP5K2 MECP2

2.88e-0410532GO:0006020
GeneOntologyBiologicalProcessplasma membrane bounded cell projection assembly

CFAP47 MAPRE1 CDC42EP4 MAP4 APC KCNQ1 TOGARAM1 RAB11FIP3

2.90e-04670538GO:0120031
GeneOntologyBiologicalProcesscell projection assembly

CFAP47 MAPRE1 CDC42EP4 MAP4 APC KCNQ1 TOGARAM1 RAB11FIP3

3.36e-04685538GO:0030031
GeneOntologyBiologicalProcessDNA recombination

RAD51AP1 WRN NUCKS1 SMC5 INTS3 TOP2A

3.50e-04368536GO:0006310
GeneOntologyBiologicalProcesscell division

MAPRE1 HAUS8 WAPL MAP4 APC SMC5 TOP2A RAB11FIP3

3.77e-04697538GO:0051301
GeneOntologyBiologicalProcessorganelle localization

MAPRE1 MAP4 AP3B2 NUP98 APC TACC2 BSN MECP2

4.00e-04703538GO:0051640
GeneOntologyBiologicalProcessregulation of protein localization to centrosome

APC RAB11FIP3

4.21e-0412532GO:1904779
GeneOntologyBiologicalProcessprotein localization to microtubule cytoskeleton

MAPRE1 APC RAB11FIP3

4.70e-0459533GO:0072698
GeneOntologyBiologicalProcesspositive regulation of pseudopodium assembly

CDC42EP4 APC

4.96e-0413532GO:0031274
GeneOntologyBiologicalProcessregulation of pseudopodium assembly

CDC42EP4 APC

4.96e-0413532GO:0031272
GeneOntologyBiologicalProcessprotein localization to cytoskeleton

MAPRE1 APC RAB11FIP3

5.71e-0463533GO:0044380
GeneOntologyBiologicalProcesspositive regulation of cellular component biogenesis

MAPRE1 CDC42EP4 TIRAP APC TOGARAM1 MECP2 RAB11FIP3

6.87e-04582537GO:0044089
GeneOntologyBiologicalProcessthalamus development

NCOR1 MECP2

7.60e-0416532GO:0021794
GeneOntologyBiologicalProcessregulation of cellular component biogenesis

MAPRE1 HAUS8 CDC42EP4 MAP4 TIRAP APC TOGARAM1 PEAK1 MECP2 RAB11FIP3

7.85e-0411895310GO:0044087
GeneOntologyBiologicalProcesspseudopodium assembly

CDC42EP4 APC

8.60e-0417532GO:0031269
GeneOntologyBiologicalProcessregulation of supramolecular fiber organization

MAPRE1 HAUS8 CDC42EP4 APC TOGARAM1 MECP2

8.75e-04438536GO:1902903
GeneOntologyBiologicalProcessrhythmic behavior

NCOR1 KCNA2 KCNQ1

9.13e-0474533GO:0007622
GeneOntologyBiologicalProcesshomologous recombination

RAD51AP1 NUCKS1 TOP2A

9.13e-0474533GO:0035825
GeneOntologyBiologicalProcesscilium assembly

CFAP47 MAPRE1 MAP4 KCNQ1 TOGARAM1 RAB11FIP3

9.39e-04444536GO:0060271
GeneOntologyBiologicalProcessaxonal transport

AP3B2 BSN MECP2

9.49e-0475533GO:0098930
GeneOntologyBiologicalProcessnegative regulation by host of viral process

NUCKS1 SMC5

9.65e-0418532GO:0044793
GeneOntologyBiologicalProcesscellular response to ionizing radiation

RAD51AP1 WRN NUCKS1

9.87e-0476533GO:0071479
GeneOntologyBiologicalProcesspseudopodium organization

CDC42EP4 APC

1.08e-0319532GO:0031268
GeneOntologyBiologicalProcessregulation of microtubule nucleation

HAUS8 MECP2

1.08e-0319532GO:0010968
GeneOntologyBiologicalProcessregulation of sister chromatid cohesion

WAPL SMC5

1.19e-0320532GO:0007063
GeneOntologyBiologicalProcesspotassium ion export across plasma membrane

KCNA2 KCNQ1

1.32e-0321532GO:0097623
GeneOntologyBiologicalProcesscilium organization

CFAP47 MAPRE1 MAP4 KCNQ1 TOGARAM1 RAB11FIP3

1.34e-03476536GO:0044782
GeneOntologyBiologicalProcessdouble-strand break repair

RAD51AP1 WRN NUCKS1 SMC5 INTS3

1.44e-03324535GO:0006302
GeneOntologyCellularComponentmicrotubule organizing center

MAPRE1 HAUS8 MTUS1 MAP4 WRN APC TOGARAM1 TACC2 MECP2 TOP2A CCDC116 RAB11FIP3

1.97e-069195212GO:0005815
GeneOntologyCellularComponentinterchromatin granule

SRSF2 SMC5

6.04e-055522GO:0035061
GeneOntologyCellularComponentchromosomal region

RAD51AP1 WAPL WRN NUP98 APC SMC5 TOP2A

7.83e-05421527GO:0098687
GeneOntologyCellularComponentnuclear speck

SRRM1 SRSF2 BMP2K ZC3H13 WRN SMC5 TRIP12

9.06e-05431527GO:0016607
GeneOntologyCellularComponentcentrosome

MAPRE1 HAUS8 MTUS1 WRN APC TACC2 MECP2 CCDC116 RAB11FIP3

1.06e-04770529GO:0005813
GeneOntologyCellularComponentmitotic spindle

MAPRE1 HAUS8 NCOR1 WAPL MAP4

1.41e-04201525GO:0072686
GeneOntologyCellularComponentnuclear body

SRRM1 SRSF2 BMP2K ZC3H13 WRN NUP98 NHS SMC5 TRIP12

3.48e-04903529GO:0016604
GeneOntologyCellularComponentchromosome, centromeric region

WAPL NUP98 APC SMC5 TOP2A

6.06e-04276525GO:0000775
GeneOntologyCellularComponentspindle

MAPRE1 HAUS8 NCOR1 WAPL MTUS1 MAP4

1.07e-03471526GO:0005819
GeneOntologyCellularComponentmicrotubule

MAPRE1 HAUS8 MTUS1 MAP4 APC TOGARAM1

2.01e-03533526GO:0005874
DomainNUT

NUTM2F NUTM2G

6.44e-055482IPR024310
DomainNUT_N

NUTM2F NUTM2G

6.44e-055482IPR024309
DomainNUT

NUTM2F NUTM2G

6.44e-055482PF12881
DomainCH

CFAP47 EHBP1 MAPRE1

7.73e-0470483PF00307
Domain-

CFAP47 EHBP1 MAPRE1

8.05e-04714831.10.418.10
DomainCH

CFAP47 EHBP1 MAPRE1

8.73e-0473483PS50021
DomainCH-domain

CFAP47 EHBP1 MAPRE1

9.45e-0475483IPR001715
DomainARM-type_fold

WAPL AP3B2 APC TOGARAM1 TRIP12

1.73e-03339485IPR016024
DomainSANT_dom

NCOR1 MTA3

2.02e-0326482IPR017884
DomainSANT

NCOR1 MTA3

2.34e-0328482PS51293
Domain-

AP3B2 APC TOGARAM1 TRIP12

2.51e-032224841.25.10.10
DomainVG_K_chnl

KCNA2 KCNQ1

3.25e-0333482IPR028325
DomainMyb_DNA-binding

NCOR1 MTA3

3.65e-0335482PF00249
DomainMYB_LIKE

NCOR1 MTA3

4.29e-0338482PS50090
DomainARM-like

AP3B2 APC TOGARAM1 TRIP12

5.05e-03270484IPR011989
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

SRRM1 SCAF1 NCOR1 WAPL SRSF2 MAP4 ZC3H13 NUP98 NUCKS1 ELK3 INTS3 PRG4 TRIP12 MECP2 TOP2A

5.50e-13774541515302935
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

SRRM1 NCOR1 SRSF2 MAP4 ZC3H13 NUP98 APC NUCKS1 NHS TACC2 TRIP12 TOP2A

1.45e-11503541216964243
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

SRRM1 RAD51AP1 NCOR1 WAPL SRSF2 MAP4 ZC3H13 NUP98 SMC5 UBN2 TRIP12 MECP2 TOP2A

1.80e-09954541336373674
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

EHBP1 SRRM1 HAUS8 CDC42EP4 MTUS1 MAP4 APC NHS PEAK1 PPIP5K2 TRIP12 SH3RF3

6.49e-09861541236931259
Pubmed

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.

SRRM1 SCAF1 NCOR1 WAPL SRSF2 BMP2K MAP4 ZC3H13 WRN NUP98 PPIP5K2 INTS3 TRIP12 TOP2A

9.23e-091318541430463901
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

MAPRE1 SRRM1 NCOR1 CDC42EP4 BMP2K SCARF2 WRN NUP98 APC PEAK1 TRIP12

2.58e-08777541135844135
Pubmed

Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.

NCOR1 WAPL MAP4 WRN TRIP12 MECP2 TOP2A

2.80e-0728354730585729
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

SRRM1 RAD51AP1 WAPL MTA3 WRN UBN2 TRIP12 MECP2 TOP2A

3.79e-0760854936089195
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

SRRM1 SCAF1 NCOR1 SRSF2 ZC3H13 WRN NUP98 INTS3 UBN2 TRIP12 MECP2 TOP2A

5.40e-071294541230804502
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

MAPRE1 WAPL BMP2K MAP4 ZC3H13 APC TACC2 PEAK1 UBN2 TRIP12 RAB11FIP3

7.19e-071084541111544199
Pubmed

Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.

SRRM1 KCNA2 CDC42EP4 MAP4 APC BSN MECP2

1.10e-0634754717114649
Pubmed

SR protein kinases promote splicing of nonconsensus introns.

MAPRE1 SRRM1 SCAF1 MAP4 ZC3H13 TOGARAM1 TRIP12

1.43e-0636154726167880
Pubmed

APC and EB1 function together in mitosis to regulate spindle dynamics and chromosome alignment.

MAPRE1 APC

2.37e-06254216030254
Pubmed

Prognostic Impact of Genetic Variants of MECP2 and TIRAP on Clinical Outcomes of Systemic Lupus Erythematosus with and without Nephritis.

TIRAP MECP2

2.37e-06254234572591
Pubmed

Adenomatous polyposis coli on microtubule plus ends in cell extensions can promote microtubule net growth with or without EB1.

MAPRE1 APC

2.37e-06254216525027
Pubmed

Negative regulation of EB1 turnover at microtubule plus ends by interaction with microtubule-associated protein ATIP3.

MAPRE1 MTUS1

2.37e-06254226498358
Pubmed

RAD51AP1 Loss Attenuates Colorectal Cancer Stem Cell Renewal and Sensitizes to Chemotherapy.

RAD51AP1 APC

2.37e-06254234099522
Pubmed

Combinatorial expression of microtubule-associated EB1 and ATIP3 biomarkers improves breast cancer prognosis.

MAPRE1 MTUS1

2.37e-06254230368744
Pubmed

The role of KCNQ1 in mouse and human gastrointestinal cancers.

APC KCNQ1

2.37e-06254223975432
Pubmed

EB1 Directly Regulates APC-Mediated Actin Nucleation.

MAPRE1 APC

2.37e-06254233007249
Pubmed

Interaction between tumor suppressor adenomatous polyposis coli and topoisomerase IIalpha: implication for the G2/M transition.

APC TOP2A

2.37e-06254218632987
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

MAPRE1 SRRM1 NCOR1 WAPL MTA3 MAP4 NUP98 NUCKS1 SMC5 TOP2A

3.17e-061014541032416067
Pubmed

Recruitment of the human TREX complex to mRNA during splicing.

SRRM1 SRSF2 ZC3H13

3.96e-062054315998806
Pubmed

A bead-based approach for large-scale identification of in vitro kinase substrates.

SRRM1 SRSF2 ZC3H13 NUP98 TOP2A

5.59e-0616354522113938
Pubmed

Regulation and function of the interaction between the APC tumour suppressor protein and EB1.

MAPRE1 APC

7.09e-06354210773885
Pubmed

KIF17 stabilizes microtubules and contributes to epithelial morphogenesis by acting at MT plus ends with EB1 and APC.

MAPRE1 APC

7.09e-06354220696710
Pubmed

A relay mechanism between EB1 and APC facilitate STIM1 puncta assembly at endoplasmic reticulum-plasma membrane junctions.

MAPRE1 APC

7.09e-06354223871111
Pubmed

The formin mDia2 stabilizes microtubules independently of its actin nucleation activity.

MAPRE1 APC

7.09e-06354218458159
Pubmed

Critical role for the EB1 and APC interaction in the regulation of microtubule polymerization.

MAPRE1 APC

7.09e-06354211470413
Pubmed

APC binds to the novel protein EB1.

MAPRE1 APC

7.09e-0635427606712
Pubmed

Amer2 protein interacts with EB1 protein and adenomatous polyposis coli (APC) and controls microtubule stability and cell migration.

MAPRE1 APC

7.09e-06354222898821
Pubmed

APC sensitive gastric acid secretion.

APC KCNQ1

7.09e-06354219255508
Pubmed

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.

HAUS8 MTA3 NUP98 INTS3 TRIP12 MECP2 TOP2A

7.95e-0646954727634302
Pubmed

The Ski protein family is required for MeCP2-mediated transcriptional repression.

NCOR1 MECP2

1.42e-05454211441023
Pubmed

The acute myeloid leukemia-associated protein, DEK, forms a splicing-dependent interaction with exon-product complexes.

SRRM1 SRSF2

1.42e-05454210908574
Pubmed

Proto-Oncogenic Src Phosphorylates EB1 to Regulate the Microtubule-Focal Adhesion Crosstalk and Stimulate Cell Migration.

MAPRE1 APC

1.42e-05454227698945
Pubmed

Involvement of the telomeric protein Pin2/TRF1 in the regulation of the mitotic spindle.

MAPRE1 APC

1.42e-05454211943150
Pubmed

NUCKS1 promotes RAD54 activity in homologous recombination DNA repair.

RAD51AP1 NUCKS1

1.42e-05454232876692
Pubmed

Increased plasma levels of the APC-interacting protein MAPRE1, LRG1, and IGFBP2 preceding a diagnosis of colorectal cancer in women.

MAPRE1 APC

1.42e-05454222277732
Pubmed

PRP19 transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitry.

WAPL MAP4 WRN INTS3 TRIP12 TOP2A

1.45e-0534054624332808
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

MAPRE1 HAUS8 BMP2K MAP4 APC SMC5 UBN2 TRIP12

1.52e-0572454836232890
Pubmed

Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.

EHBP1 NCOR1 CDC42EP4 TACC2 ELK3 PEAK1 PPIP5K2

1.88e-0553654715840001
Pubmed

Exchangeable gene trap using the Cre/mutated lox system.

EHBP1 NCOR1 CDC42EP4 TACC2 ELK3 PEAK1 PPIP5K2

1.92e-0553854710512203
Pubmed

The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.

SRRM1 WAPL PIPSL TRIP12 TOP2A

1.99e-0521254533853758
Pubmed

Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme Formation.

SRRM1 SRSF2 MTUS1 ZC3H13 APC PEAK1

2.04e-0536154630344098
Pubmed

Functional analysis of the human CDC5L complex and identification of its components by mass spectrometry.

SRRM1 SRSF2 TOP2A

2.05e-053454311101529
Pubmed

NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency.

SRRM1 MTA3 TRIP12 TOP2A

2.05e-0510354432744500
Pubmed

Genomic analysis of mouse retinal development.

NCOR1 CDC42EP4 MTUS1 NUP98 APC NUCKS1 TACC2 BSN UBN2

2.26e-05100654915226823
Pubmed

Evidence that an interaction between EB1 and p150(Glued) is required for the formation and maintenance of a radial microtubule array anchored at the centrosome.

MAPRE1 APC

2.36e-05554212388762
Pubmed

EB/RP gene family encodes tubulin binding proteins.

MAPRE1 APC

2.36e-05554210188731
Pubmed

Membrane localization of adenomatous polyposis coli protein at cellular protrusions: targeting sequences and regulation by beta-catenin.

MAPRE1 APC

2.36e-05554216621792
Pubmed

Characterization of functional domains of human EB1 family proteins.

MAPRE1 APC

2.36e-05554214514668
Pubmed

Topoisomerase II-Induced Chromosome Breakage and Translocation Is Determined by Chromosome Architecture and Transcriptional Activity.

WAPL TOP2A

3.54e-05654231202577
Pubmed

Structure of the MeCP2-TBLR1 complex reveals a molecular basis for Rett syndrome and related disorders.

NCOR1 MECP2

3.54e-05654228348241
Pubmed

An EB1-binding motif acts as a microtubule tip localization signal.

MAPRE1 APC

3.54e-05654219632184
Pubmed

EB1 and APC bind to mDia to stabilize microtubules downstream of Rho and promote cell migration.

MAPRE1 APC

3.54e-05654215311282
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

SRRM1 SRSF2 ZC3H13 KCTD3 APC NUCKS1 PPIP5K2 TRIP12 MECP2

3.99e-05108254938697112
Pubmed

Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.

SRRM1 NCOR1 WAPL SRSF2 ZC3H13 NUP98 TRIP12 TOP2A

4.63e-0584754835850772
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

MAPRE1 HAUS8 NCOR1 MTUS1 BMP2K APC PPIP5K2 TOP2A

4.86e-0585354828718761
Pubmed

MTA3 and the Mi-2/NuRD complex regulate cell fate during B lymphocyte differentiation.

NCOR1 MTA3

4.94e-05754215454082
Pubmed

NUCKS1 is a novel RAD51AP1 paralog important for homologous recombination and genome stability.

RAD51AP1 NUCKS1

4.94e-05754226323318
Pubmed

Accelerating novel candidate gene discovery in neurogenetic disorders via whole-exome sequencing of prescreened multiplex consanguineous families.

KCTD3 FAM120AOS

4.94e-05754225558065
Pubmed

Proteomic Analysis of the EWS-Fli-1 Interactome Reveals the Role of the Lysosome in EWS-Fli-1 Turnover.

MAPRE1 SRRM1 NCOR1 SRSF2 NUCKS1 UBN2

5.06e-0542554624999758
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

SRRM1 SCAF1 RAD51AP1 WAPL MTA3 MTUS1 PCDH19 MECP2 TOP2A

5.07e-05111654931753913
Pubmed

Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.

SRRM1 BMP2K AP3B2 KCTD3 APC SMC5

5.39e-0543054632581705
Pubmed

Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry.

EHBP1 SRRM1 MAP4 ZC3H13

5.57e-0513354415144186
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

MAPRE1 SCAF1 WAPL SRSF2 MAP4 NUP98 NUCKS1 PEAK1 BSN TOP2A

5.96e-051425541030948266
Pubmed

Rett syndrome mutations abolish the interaction of MeCP2 with the NCoR/SMRT co-repressor.

NCOR1 MECP2

6.59e-05854223770565
Pubmed

Identifying microRNA/mRNA dysregulations in ovarian cancer.

RAD51AP1 TOP2A

6.59e-05854222452920
Pubmed

Prediction of the coding sequences of unidentified human genes. VIII. 78 new cDNA clones from brain which code for large proteins in vitro.

TOGARAM1 PPIP5K2 BSN

7.41e-05525439455477
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

SCAF1 SRSF2 MTA3 BMP2K MAP4 KCTD3 WRN APC UBN2 MECP2

8.98e-051497541031527615
Pubmed

TTF-1/NKX2-1 binds to DDB1 and confers replication stress resistance to lung adenocarcinomas.

WRN NUP98 MECP2 TOP2A

9.36e-0515254428192407
Pubmed

Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization.

TCEA3 NUCKS1 KCNQ1

9.76e-055754324952745
Pubmed

Scc1 sumoylation by Mms21 promotes sister chromatid recombination through counteracting Wapl.

WAPL SMC5

1.06e-041054222751501
Pubmed

EB1 acetylation by P300/CBP-associated factor (PCAF) ensures accurate kinetochore-microtubule interactions in mitosis.

MAPRE1 APC

1.06e-041054223001180
Pubmed

Bimodal regulation of an Elk subfamily K+ channel by phosphatidylinositol 4,5-bisphosphate.

KCNA2 KCNQ1

1.06e-041054226503718
Pubmed

Nuclear pore protein NUP88 activates anaphase-promoting complex to promote aneuploidy.

NUP98 APC

1.06e-041054226731471
Pubmed

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.

SRRM1 NCOR1 SRSF2 MAP4 NUP98 APC NHS TRIP12 TOP2A

1.18e-04124754927684187
Pubmed

Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.

MAPRE1 MAP4 AP3B2 PPIP5K2 TRIP12 TOP2A

1.21e-0449854636634849
Pubmed

A myelin-related transcriptomic profile is shared by Pitt-Hopkins syndrome models and human autism spectrum disorder.

APC MECP2

1.29e-041154232015540
Pubmed

Conditional mutation of Smc5 in mouse embryonic stem cells perturbs condensin localization and mitotic progression.

SMC5 TOP2A

1.29e-041154226919979
Pubmed

SRPK2: a differentially expressed SR protein-specific kinase involved in mediating the interaction and localization of pre-mRNA splicing factors in mammalian cells.

SRRM1 SRSF2

1.29e-04115429472028
Pubmed

A Network of Conserved Synthetic Lethal Interactions for Exploration of Precision Cancer Therapy.

WRN APC TOP2A

1.44e-046554327453043
Pubmed

Cracking the egg: molecular dynamics and evolutionary aspects of the transition from the fully grown oocyte to embryo.

CFAP47 HAUS8 WAPL MTUS1 TRIP12

1.52e-0432654517015433
Pubmed

SMC5/6 is required for the formation of segregation-competent bivalent chromosomes during meiosis I in mouse oocytes.

SMC5 TOP2A

1.55e-041254228302748
Pubmed

Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.

MAP4 SCARF2 KCNQ1 ELK3 PRG4

1.59e-0432954517474147
Pubmed

ZBTB2 protein is a new partner of the Nucleosome Remodeling and Deacetylase (NuRD) complex.

SCAF1 SRSF2 MTA3 MECP2 TOP2A

1.61e-0433054533301849
Pubmed

Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.

NCOR1 WAPL MAP4 INTS3 TOP2A

1.66e-0433254532786267
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

WAPL NYAP2 MTA3 MTUS1 PPIP5K2 BSN

1.67e-0452954614621295
Pubmed

Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.

SRRM1 MTA3 INTS3 TRIP12 MECP2 TOP2A

1.74e-0453354630554943
Pubmed

Genome-wide CRISPR-Cas9 Screen Identifies Leukemia-Specific Dependence on a Pre-mRNA Metabolic Pathway Regulated by DCPS.

NUP98 SMC5 INTS3 TRIP12 TOP2A

1.85e-0434054529478914
Pubmed

Defining the NSD2 interactome: PARP1 PARylation reduces NSD2 histone methyltransferase activity and impedes chromatin binding.

NUCKS1 MECP2 TOP2A

1.96e-047254331248990
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

NCOR1 WAPL MAP4 PEAK1 UBN2 TOP2A

2.05e-0454954638280479
Pubmed

A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.

HAUS8 NCOR1 WAPL MTA3 MAP4 TOP2A

2.28e-0456054635241646
Pubmed

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.

MAPRE1 SRRM1 MTUS1 MAP4 NUP98 NUCKS1 GPNMB INTS3 TOP2A

2.35e-04136754932687490
Pubmed

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.

EHBP1 MAPRE1 CDC42EP4 MAP4 NHS PEAK1

2.39e-0456554625468996
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

TCEA3 SRRM1 SCAF1 SRSF2 MAP4 WRN PIPSL TRIP12 MECP2

2.40e-04137154936244648
Pubmed

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.

MAPRE1 SRRM1 SRSF2 MAP4 ZC3H13 NUCKS1 TOP2A

2.42e-0480754722681889
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

SRRM1 WAPL SRSF2 INTS3 TRIP12 TOP2A

2.80e-0458254620467437
Pubmed

SNX27-driven membrane localisation of OTULIN antagonises linear ubiquitination and NF-κB signalling activation.

WAPL NYAP2 MAP4 ZC3H13 KCTD3

3.02e-0437854534315543
InteractionNUP43 interactions

MAPRE1 SRRM1 SCAF1 NCOR1 MAP4 ZC3H13 WRN NUP98 APC UBN2 TRIP12 MECP2 TOP2A

7.47e-096255413int:NUP43
InteractionPPP1CA interactions

MAPRE1 SRRM1 NCOR1 SRSF2 BMP2K MAP4 KCTD3 APC KCNQ1 PEAK1 MECP2 TOP2A

2.37e-076965412int:PPP1CA
InteractionNR2C2 interactions

SRRM1 SCAF1 NCOR1 WAPL SRSF2 BMP2K MAP4 ZC3H13 WRN NUP98 ELK3 PPIP5K2 SMC5 INTS3 TRIP12 TOP2A

4.69e-0714035416int:NR2C2
InteractionCBX3 interactions

SRRM1 RAD51AP1 NCOR1 WAPL ZC3H13 NUCKS1 SMC5 UBN2 TRIP12 MECP2 TOP2A

9.21e-076465411int:CBX3
InteractionSMC5 interactions

SRRM1 RAD51AP1 NCOR1 WAPL SRSF2 MAP4 ZC3H13 NUP98 SMC5 UBN2 TRIP12 MECP2 TOP2A

1.70e-0610005413int:SMC5
InteractionPPP1CC interactions

SRRM1 NCOR1 SRSF2 MTUS1 BMP2K ZC3H13 APC TACC2 PEAK1 SMC5 MECP2

3.35e-067385411int:PPP1CC
InteractionCEP104 interactions

MAPRE1 SRRM1 HAUS8 MTUS1 TOGARAM1

4.00e-0689545int:CEP104
InteractionKDM5B interactions

NCOR1 MTA3 BMP2K NUCKS1 MECP2

7.09e-06100545int:KDM5B
InteractionSRPK2 interactions

MAPRE1 SRRM1 SCAF1 SRSF2 CDC42EP4 MAP4 ZC3H13 TOGARAM1 TRIP12 TOP2A

1.77e-057175410int:SRPK2
InteractionSUMO2 interactions

NCOR1 WAPL MAP4 WRN ELK3 SMC5 INTS3 TRIP12 TOP2A

2.47e-05591549int:SUMO2
InteractionH3-3A interactions

RAD51AP1 WAPL MTA3 WRN KCNQ1 SMC5 UBN2 TRIP12 MECP2 TOP2A

2.57e-057495410int:H3-3A
InteractionYWHAH interactions

EHBP1 SRRM1 HAUS8 CDC42EP4 MTUS1 ZC3H13 APC NHS PEAK1 PPIP5K2 TRIP12 SH3RF3

2.73e-0511025412int:YWHAH
InteractionSTAG2 interactions

SRRM1 WAPL PIPSL SMC5 INTS3 TRIP12

2.92e-05224546int:STAG2
InteractionNUMA1 interactions

MAPRE1 SRRM1 NUP98 NUCKS1 SMC5 INTS3 TRIP12 TOP2A

3.30e-05469548int:NUMA1
InteractionMAPRE3 interactions

MAPRE1 HAUS8 MTUS1 MAP4 APC TACC2

3.38e-05230546int:MAPRE3
InteractionSRP54 interactions

CFAP47 MAPRE1 NUP98 MECP2 TOP2A

3.75e-05141545int:SRP54
InteractionTRIM36 interactions

MAPRE1 HAUS8 MTUS1 MAP4 APC

4.15e-05144545int:TRIM36
InteractionSNRNP40 interactions

MAPRE1 SRRM1 SCAF1 NCOR1 ZC3H13 WRN UBN2 MECP2 TOP2A

4.44e-05637549int:SNRNP40
InteractionRANBP2 interactions

MAPRE1 SRRM1 NUP98 APC SMC5 MECP2 TOP2A

4.79e-05361547int:RANBP2
InteractionGIGYF2 interactions

MAPRE1 KCTD3 APC SMC5 SH3RF3 TOP2A

7.13e-05263546int:GIGYF2
InteractionMAGOH interactions

MAPRE1 SRRM1 SRSF2 ZC3H13 MECP2 TOP2A

7.28e-05264546int:MAGOH
InteractionTOP2B interactions

SRRM1 NUCKS1 PIPSL SMC5 MECP2 TOP2A

7.59e-05266546int:TOP2B
InteractionSSRP1 interactions

SRRM1 SCAF1 NCOR1 MTA3 ZC3H13 SMC5 INTS3 MECP2 TOP2A

7.77e-05685549int:SSRP1
InteractionPRKDC interactions

SRRM1 NCOR1 SRSF2 MAP4 WRN NUCKS1 SMC5 MECP2 TOP2A

8.68e-05695549int:PRKDC
InteractionSNRPD2 interactions

MAPRE1 SRRM1 SRSF2 MAP4 SMC5 MECP2 TOP2A

1.13e-04414547int:SNRPD2
InteractionSMARCE1 interactions

MAPRE1 NCOR1 NUCKS1 SMC5 TRIP12 MECP2

1.15e-04287546int:SMARCE1
InteractionRAD51AP1 interactions

RAD51AP1 NUCKS1 SMC5

1.22e-0436543int:RAD51AP1
InteractionSRSF1 interactions

SRRM1 SCAF1 SRSF2 NUCKS1 SMC5 TRIP12 MECP2 TOP2A

1.29e-04570548int:SRSF1
InteractionRBBP4 interactions

NCOR1 MTA3 NUCKS1 SMC5 INTS3 UBN2 MECP2 TOP2A

1.34e-04573548int:RBBP4
InteractionH2BC8 interactions

RAD51AP1 WAPL SRSF2 NUCKS1 INTS3 TRIP12 MECP2 TOP2A

1.39e-04576548int:H2BC8
InteractionNAV3 interactions

EHBP1 MAPRE1 APC

1.44e-0438543int:NAV3
InteractionVEZF1 interactions

ELK3 SMC5 MECP2 TOP2A

1.80e-04105544int:VEZF1
InteractionCSNK2A1 interactions

SRRM1 NCOR1 SRSF2 ZC3H13 NUP98 APC NUCKS1 MECP2 TOP2A CCDC116

1.97e-049565410int:CSNK2A1
InteractionSNRNP200 interactions

SRRM1 WAPL SRSF2 TIRAP APC SMC5 MECP2

2.16e-04460547int:SNRNP200
InteractionHMGXB4 interactions

NCOR1 MTA3 SMC5 MECP2

2.39e-04113544int:HMGXB4
InteractionPLRG1 interactions

SRRM1 SRSF2 SMC5 MECP2 TOP2A

2.79e-04216545int:PLRG1
InteractionTERF2 interactions

BMP2K ZC3H13 WRN SMC5 MECP2 TOP2A

2.88e-04340546int:TERF2
InteractionUPF3A interactions

SRRM1 WAPL MECP2

2.89e-0448543int:UPF3A
InteractionCLK1 interactions

SRRM1 NCOR1 SRSF2 ZC3H13 MECP2

2.97e-04219545int:CLK1
InteractionNUCKS1 interactions

RAD51AP1 NUCKS1 INTS3 MECP2 TOP2A

3.03e-04220545int:NUCKS1
InteractionU2AF2 interactions

MAPRE1 SRRM1 SCAF1 SRSF2 MAP4 ZC3H13 SMC5 MECP2

3.18e-04651548int:U2AF2
InteractionZC3H15 interactions

MAPRE1 PPIP5K2 SMC5 MECP2

3.20e-04122544int:ZC3H15
InteractionSRRM1 interactions

SRRM1 WAPL SRSF2 SMC5 MECP2 TOP2A

3.26e-04348546int:SRRM1
InteractionEIF4A3 interactions

MAPRE1 SRRM1 SRSF2 ZC3H13 WRN SMC5 MECP2

3.54e-04499547int:EIF4A3
InteractionEED interactions

SRRM1 NCOR1 SRSF2 MTA3 BMP2K ZC3H13 NUP98 NUCKS1 SMC5 INTS3 TRIP12 TOP2A

3.59e-0414455412int:EED
InteractionSRCAP interactions

NCOR1 NUCKS1 PIPSL MECP2

3.73e-04127544int:SRCAP
InteractionFOXI2 interactions

WAPL NUP98 MECP2

3.87e-0453543int:FOXI2
InteractionYWHAG interactions

EHBP1 SRRM1 HAUS8 MTUS1 ZC3H13 APC NHS PEAK1 PPIP5K2 TRIP12 SH3RF3

3.99e-0412485411int:YWHAG
InteractionAP2S1 interactions

BMP2K MAP4 APC MECP2

4.07e-04130544int:AP2S1
InteractionTEAD2 interactions

INTS3 UBN2 TRIP12 MECP2

4.07e-04130544int:TEAD2
InteractionRAE1 interactions

MAPRE1 MAP4 NUP98 SMC5 MECP2

4.18e-04236545int:RAE1
InteractionBLM interactions

MAP4 WRN SMC5 MECP2 TOP2A

4.43e-04239545int:BLM
InteractionMGA interactions

NCOR1 WAPL ELK3 PIPSL SMC5

4.52e-04240545int:MGA
InteractionTOMM20 interactions

EHBP1 NUP98 APC TACC2 PEAK1

4.52e-04240545int:TOMM20
InteractionCWC15 interactions

SRRM1 SRSF2 SMC5 TOP2A

4.57e-04134544int:CWC15
InteractionISY1 interactions

MAPRE1 SRRM1 SMC5 MECP2

4.70e-04135544int:ISY1
InteractionSFN interactions

HAUS8 SRSF2 MTUS1 MAP4 APC NHS PEAK1 TRIP12

4.78e-04692548int:SFN
InteractionNUP54 interactions

MAPRE1 HAUS8 NUP98 APC

4.83e-04136544int:NUP54
InteractionPDS5A interactions

SRRM1 WAPL TIRAP SMC5 MECP2

4.96e-04245545int:PDS5A
InteractionNPAS1 interactions

HAUS8 MTUS1 KCTD3 INTS3 TRIP12

4.96e-04245545int:NPAS1
InteractionMECP2 interactions

SRRM1 NCOR1 SRSF2 ZC3H13 KCTD3 APC NUCKS1 PPIP5K2 SMC5 TRIP12 MECP2

5.18e-0412875411int:MECP2
InteractionPOLR2A interactions

SCAF1 SRSF2 MAP4 ZC3H13 SMC5 INTS3 MECP2

5.43e-04536547int:POLR2A
InteractionPOLR1D interactions

CDC42EP4 UBN2 TRIP12 MECP2

5.54e-04141544int:POLR1D
InteractionMAD2L1 interactions

MTA3 NUP98 APC PEAK1 PPIP5K2

5.64e-04252545int:MAD2L1
InteractionCPSF1 interactions

SRRM1 NCOR1 WRN TRIP12 MECP2

5.95e-04255545int:CPSF1
InteractionH3C1 interactions

NCOR1 WAPL MTA3 NUCKS1 SMC5 UBN2 TRIP12 MECP2 TOP2A

5.96e-04901549int:H3C1
InteractionEMSY interactions

NUP98 NUCKS1 ELK3 SMC5

6.15e-04145544int:EMSY
InteractionPARP1 interactions

SRRM1 SCAF1 RAD51AP1 SRSF2 MTA3 WRN NUCKS1 SMC5 TRIP12 MECP2 TOP2A

6.25e-0413165411int:PARP1
InteractionTCF20 interactions

MTA3 NUCKS1 SMC5 MECP2

6.31e-04146544int:TCF20
InteractionYWHAZ interactions

MAPRE1 RAD51AP1 NCOR1 MTUS1 APC NHS TACC2 PEAK1 PPIP5K2 SMC5 TRIP12

6.37e-0413195411int:YWHAZ
InteractionLETMD1 interactions

KCNA2 PIPSL MECP2

6.45e-0463543int:LETMD1
InteractionFHL2 interactions

NCOR1 WAPL CDC42EP4 MTUS1 BMP2K APC

6.46e-04396546int:FHL2
InteractionCHAMP1 interactions

NUCKS1 PIPSL SMC5 MECP2

6.64e-04148544int:CHAMP1
InteractionCALD1 interactions

SRRM1 PEAK1 SMC5 UBN2 TRIP12

7.08e-04265545int:CALD1
InteractionPOGZ interactions

NUCKS1 ELK3 PIPSL SMC5 MECP2

7.08e-04265545int:POGZ
InteractionKIF11 interactions

MAPRE1 NCOR1 MTUS1 MAP4 NUTM2F

7.32e-04267545int:KIF11
InteractionATRX interactions

RAD51AP1 WRN NUCKS1 SMC5 MECP2

7.32e-04267545int:ATRX
InteractionSNW1 interactions

SRRM1 NCOR1 WAPL SRSF2 SMC5 INTS3 TRIP12 MECP2

7.89e-04747548int:SNW1
InteractionFNBP4 interactions

MTUS1 SMC5 MECP2

8.06e-0468543int:FNBP4
InteractionBAZ1A interactions

NCOR1 NUCKS1 SMC5 MECP2

8.09e-04156544int:BAZ1A
InteractionSMARCA5 interactions

MTA3 ZC3H13 NUCKS1 PIPSL SMC5 MECP2

8.24e-04415546int:SMARCA5
InteractionUNC13A interactions

BSN MECP2

8.26e-0416542int:UNC13A
InteractionSOX6 interactions

NCOR1 MTA3 UBN2 TRIP12

8.28e-04157544int:SOX6
InteractionSMC1A interactions

SRRM1 WAPL MTUS1 SMC5 INTS3 MECP2

8.55e-04418546int:SMC1A
InteractionHNRNPCL1 interactions

SCAF1 PPIP5K2 SMC5 MECP2

9.09e-04161544int:HNRNPCL1
InteractionABT1 interactions

SRRM1 SCAF1 NCOR1 PIPSL SRRM3 TRIP12

9.10e-04423546int:ABT1
InteractionBRD2 interactions

SRRM1 MTA3 ELK3 SMC5 MECP2 TOP2A

9.78e-04429546int:BRD2
InteractionADAR interactions

WAPL WRN SMC5 MECP2 TOP2A

9.96e-04286545int:ADAR
InteractionCEP97 interactions

MAPRE1 HAUS8 KCTD3 PIPSL

9.96e-04165544int:CEP97
InteractionCSTF2 interactions

SRRM1 MAP4 SMC5 MECP2

9.96e-04165544int:CSTF2
InteractionRBBP5 interactions

ZC3H13 NUCKS1 ELK3 MECP2 TOP2A

1.01e-03287545int:RBBP5
InteractionSUMO1 interactions

MAPRE1 WRN SMC5 MECP2 TOP2A

1.01e-03287545int:SUMO1
InteractionCBX1 interactions

MAPRE1 MAP4 NUCKS1 SMC5 MECP2

1.03e-03288545int:CBX1
InteractionEP300 interactions

MAPRE1 NCOR1 SRSF2 MAP4 NUP98 NUCKS1 TACC2 BSN NUTM2F MECP2 TOP2A

1.05e-0314015411int:EP300
InteractionSRSF2 interactions

SRRM1 SRSF2 SMC5 MECP2 TOP2A

1.06e-03290545int:SRSF2
InteractionNAA40 interactions

EHBP1 WAPL MAP4 NUP98 NUCKS1 TACC2 SMC5 MECP2 TOP2A

1.07e-03978549int:NAA40
InteractionPRPF3 interactions

MAPRE1 SRRM1 SRSF2 SMC5 MECP2

1.08e-03291545int:PRPF3
InteractionSLC6A4 interactions

SRRM1 BMP2K AP3B2 KCTD3 APC SMC5

1.08e-03437546int:SLC6A4
InteractionDHX8 interactions

SRRM1 SCAF1 ZC3H13 WRN MECP2

1.09e-03292545int:DHX8
Cytoband2q36.3

NYAP2 TRIP12

3.09e-04225422q36.3
GeneFamilyPotassium voltage-gated channels

KCNA2 KCNQ1

1.17e-0340232274
GeneFamilyGATA zinc finger domain containing|Myb/SANT domain containing

NCOR1 MTA3

2.05e-0353232532
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

NCOR1 APC

2.20e-02181232694
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

EHBP1 WAPL BMP2K WRN NUP98 APC TOGARAM1 PPIP5K2 SMC5 TRIP12 MECP2 TOP2A

1.06e-078565312M4500
CoexpressionDAZARD_UV_RESPONSE_CLUSTER_G6

WAPL MTUS1 TOGARAM1 SMC5 MECP2 TOP2A

4.79e-07145536M1810
CoexpressionDAZARD_RESPONSE_TO_UV_NHEK_DN

WAPL MTUS1 TOGARAM1 PPIP5K2 SMC5 MECP2 TOP2A

2.36e-06300537M8702
CoexpressionFISCHER_DREAM_TARGETS

EHBP1 SRRM1 HAUS8 RAD51AP1 SRSF2 CDC42EP4 WRN NUP98 NUCKS1 SMC5 TOP2A

3.06e-069695311M149
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN

EHBP1 WAPL WRN NUP98 SMC5 TRIP12 MECP2 TOP2A

4.13e-06466538M13522
CoexpressionGSE18804_BRAIN_VS_COLON_TUMORAL_MACROPHAGE_UP

MAPRE1 PCDH19 NHS GPNMB BSN

4.54e-05194535M10021
CoexpressionMORI_PLASMA_CELL_DN

MTA3 BMP2K ELK3

5.32e-0536533M19509
CoexpressionMORI_PLASMA_CELL_DN

MTA3 BMP2K ELK3

6.26e-0538533MM598
ToppCell(08)_Brush+PNEC-(2)_GFP_FOXI1|(08)_Brush+PNEC / shred by cell type by condition

SRRM1 MTUS1 ZC3H13 APC TRIP12

7.07e-07138545817e3f639604ea95adae01e8685ffaa2e0aff7a8
ToppCell(03)_KRT6B+-(2)_GFP_FOXI1|(03)_KRT6B+ / shred by cell type by condition

SRRM1 NCOR1 MTUS1 ZC3H13 NUCKS1

4.27e-06199545c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCellPND14-Immune-Immune_Myeloid-DC-cDC2-cDC2_G2M|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RAD51AP1 NUCKS1 BSN TOP2A

5.13e-05168544b7cd33f5da4f37b9384fc3bd3ca01fbc790accfc
ToppCellPND07-Epithelial-Epithelial_Airway-Neurosecretory|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MTUS1 AP3B2 WEE2 SRRM3

6.01e-0517554419eda8b5d39dc93d79737ebdbeeba5ec0cb23c51
ToppCellPND10-Immune-Immune_Myeloid-Dendritic-cDC1|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HAUS8 TIRAP NUCKS1 TOP2A

7.15e-05183544ab38264daddccdf5ffb75ff2210b27423eca6bc0
ToppCellPND10-Immune-Immune_Myeloid-Dendritic|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HAUS8 TIRAP NUCKS1 TOP2A

7.15e-05183544e4911601dca2c0ecb448cdb6b222dedfc0c8bf6c
ToppCellPND10-Immune-Immune_Myeloid-Dendritic-cDC1-cDC1_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HAUS8 TIRAP NUCKS1 TOP2A

7.15e-05183544263bfa1d8a7314bc3156c735c403c3bab8ea4dac
ToppCell5'-GW_trimst-1-SmallIntestine-Endothelial-blood_vessel_EC-venous_capillary|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MTUS1 KCNQ1 ELK3 SH3RF3

7.30e-0518454497e97de52daaff8840f4ee76a94ba5e3f79de7ce
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1|TCGA-Pancreas / Sample_Type by Project: Shred V9

WAPL TIRAP ZC3H13 APC

7.61e-0518654403db813598b67b1e08f759758a1c2023396921fa
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-intestinal_crypt_stem_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAD51AP1 MTUS1 KCNQ1 NHS

8.26e-0519054452c59001a079c76249abbaa3141e9e661b83d9a0
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCOR1 WAPL BMP2K SMC5

8.43e-0519154460c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCellE17.5-Endothelial-proliferative_endothelial_cell-proliferative_endothelial_cell|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

RAD51AP1 NUCKS1 ELK3 TOP2A

8.43e-05191544efe0cb0b6602621f5eda72a723b83b38bf15607f
ToppCellE17.5-Endothelial-proliferative_endothelial_cell|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

RAD51AP1 NUCKS1 ELK3 TOP2A

8.43e-0519154400676c598f6dae0ff9158d064248f1265432f3e1
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCOR1 WAPL BMP2K SMC5

8.43e-05191544973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
ToppCellThalamus-Neuronal|Thalamus / BrainAtlas - Mouse McCarroll V32

NYAP2 BSN SRRM3 MECP2

8.78e-05193544712a4acd1167e43543950bc819ff11984e6f718d
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

HAUS8 RAD51AP1 NHS TOP2A

8.78e-05193544516ea2c12bdc7a5dc676159d627e36f6abe13ef0
ToppCellParenchymal-10x5prime-Epithelial-Epi_alveolar-Dividing_AT2|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

TCEA3 MTUS1 TACC2 TOP2A

8.78e-0519354444839a606ae2f8e37421bda46d588189e1c943d2
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-AC-like-AC-like_Prolif-A|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

RAD51AP1 CDC42EP4 NUCKS1 TOP2A

8.78e-05193544ecbe1bd16df547427da5e69a3017300e766c2899
ToppCelldroplet-Tongue-nan-3m-Epithelial-proliferating|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HAUS8 RAD51AP1 NUCKS1 TOP2A

8.95e-051945442cac1b9c4da01faaec9a67ec06f47a7060760225
ToppCelldroplet-Tongue-TONGUE-1m-Epithelial-proliferating|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HAUS8 RAD51AP1 NUCKS1 TOP2A

9.13e-05195544b57132802cb977551e214880984f3edcd375474f
ToppCellfacs-Aorta-Heart-3m-Endothelial-aorta_endothelial_cell|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDC42EP4 MTUS1 KCNQ1 ELK3

9.13e-051955443969b8d5fcec8ef1831531a781f7bbcebab5a4ba
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-AC-like-AC-like_Prolif-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

RAD51AP1 CDC42EP4 NUCKS1 TOP2A

9.69e-051985447225a6194c52b01c581e58d3cda107c4af96dc4f
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-AC-like-AC-like_Prolif-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

RAD51AP1 CDC42EP4 NUCKS1 TOP2A

9.88e-051995440da69ca107e826740f0ba3159012aa25e1b9da6a
ToppCell(04)_Interm._basal>secr.-(2)_GFP_FOXI1|(04)_Interm._basal>secr. / shred by cell type by condition

SRRM1 MTUS1 ZC3H13 TRIP12

9.88e-0519954453ca3861f9e00dab3f3fbefb0837857ee39ab084
ToppCell(09)_Interm._secr.>cil.-(2)_GFP_FOXI1|(09)_Interm._secr.>cil. / shred by cell type by condition

SRRM1 MTUS1 ZC3H13 TRIP12

9.88e-05199544fc680f85ebd3bab4c72876a19a461b0afb5f51ce
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-AC-like-AC-like_Prolif-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

RAD51AP1 CDC42EP4 NUCKS1 TOP2A

9.88e-0519954489d7622c4ae146900d963ac68c6bf011e8674665
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-AC-like-AC-like_Prolif|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

RAD51AP1 CDC42EP4 NUCKS1 TOP2A

1.01e-042005440de9e7412a1725a8acd51820aa3135a112ced36c
ToppCellTransverse-(5)_Dendritic_cell-(52)_cycling_DCs|Transverse / shred on region, Cell_type, and subtype

RAD51AP1 NHS GPNMB TOP2A

1.01e-0420054451e643d48b5e97a0e117b578a6ea7d429c6cdd1e
ToppCellTransverse-Dendritic_cell-cycling_DCs|Transverse / Region, Cell class and subclass

RAD51AP1 NHS GPNMB TOP2A

1.01e-04200544f588d8889f351c797963616a3575fa43efd46b9a
DiseaseMalignant neoplasm of breast

EHBP1 NCOR1 SCARF2 NUP98 NHS TACC2 ELK3 GPNMB TOP2A

9.75e-051074529C0006142
DiseaseIntestinal Neoplasms

APC KCNQ1

1.99e-0412522C0021841
DiseaseIntestinal Cancer

APC KCNQ1

1.99e-0412522C0346627
Diseaseacute myeloid leukemia (implicated_via_orthology)

NUP98 TOP2A

1.99e-0412522DOID:9119 (implicated_via_orthology)
Diseaseresponse to acetylsalicylate

MAP4 KCNQ1

3.60e-0416522GO_1903492
Diseasecardiovascular disease

SRRM1 SCAF1 WAPL NYAP2 WRN

1.25e-03457525EFO_0000319
DiseaseEpileptic encephalopathy

KCNA2 KCTD3

1.28e-0330522C0543888
Diseasesystolic blood pressure, body mass index

NYAP2 MAP4

1.65e-0334522EFO_0004340, EFO_0006335

Protein segments in the cluster

PeptideGeneStartEntry
SSRFTKKKPLPSISS

CCDC116

406

Q8IYX3
RPSKPTPSLATTLKS

GPNMB

331

Q14956
PTSTKKTLKPTYRTP

BMP2K

1001

Q9NSY1
RKTPPSSKSAPATKE

AP3B2

791

Q13367
PKKVSLSSDTTRKPL

RAD51AP1

276

Q96B01
PAFLTPSPTKRLSSK

RAB11FIP3

416

O75154
STKPPKSRRKAALSS

INTS3

981

Q68E01
RPTASKASKEKTPSP

NUCKS1

191

Q9H1E3
TSPLHLKSSLPTKPS

PCDH19

1066

Q8TAB3
PSKTSTKKLKTAPLP

NUP98

896

P52948
PKIPSSPDLKKSRSA

KCNA2

436

P16389
RSHTLLSPSPKPKKS

KCNQ1

401

P51787
KKPTSAKPSSTTPRL

MAP4

906

P27816
PLPKSKASLKSPALR

MTUS1

781

Q9ULD2
KASPLSTKASPLPSK

BSN

571

Q9UPA5
AKSTPKSTPVRPKSL

PEAK1

806

Q9H792
PKPKRDPSTKLSTSS

NYAP2

141

Q9P242
KPESTSFSAPRKKSP

HAUS8

126

Q9BT25
PLKPSPSKKLRSGSS

PIPSL

401

A2A3N6
GTSKLPKSLSSSPVK

CDC42EP4

131

Q9H3Q1
LSSGSKTKSPSLPPK

ELK3

276

P41970
SPIKKTSLSPTSKLG

EHBP1

751

Q8NDI1
LNKPKKPLTSSSAAP

MAPRE1

146

Q15691
PPSPASIKKTYTTSK

CFAP47

1461

Q6ZTR5
SPSPTKTTPSPRHKK

KCTD3

791

Q9Y597
PKGRSSSASSPPKKE

MECP2

351

P51608
LSPSPSPASKSKKRP

NUTM2F

686

A1L443
LSPSPSPASKSKKRP

NUTM2G

671

Q5VZR2
LSGSPLKSKSTRKPL

MTA3

516

Q9BTC8
KSRSRSKSPPKSPEE

SRSF2

201

Q01130
SRSPSPKKPLSRDKD

SRRM3

521

A6NNA2
KAKPTPPKRSSSLRK

NHS

846

Q6T4R5
LISKSNSRKSKSPIP

NCOR1

2326

O75376
KKTTKPPTLRSFLSP

FAM120AOS

241

Q5T036
PKKLLLPSSKTVSSG

WRN

1071

Q14191
PLVGSSSPTRKAKSK

SOWAHB

736

A6NEL2
SQTIKSTTKRSPKPP

PRG4

126

Q92954
SSTSPVSKKGPPLKT

APC

2241

P25054
PKPSLSAKPSVSTKL

UBN2

1061

Q6ZU65
LLAGASTKKKSRSPP

SH3RF3

726

Q8TEJ3
STKKKSRSPPSVSPT

SH3RF3

731

Q8TEJ3
SSKKARPPKESAPSS

SCAF1

791

Q9H7N4
SSSSSRSRSPPKKPP

SRRM1

361

Q8IYB3
APSPSKRKRTPSDKS

SCARF2

696

Q96GP6
SKKRTKTAPSPSLQP

WAPL

476

Q7Z5K2
SSTLKRTKKPRPPSL

TACC2

2121

O95359
FKTSSKTPSSPSKSP

TACC2

2381

O95359
SSKSKAESPKTPSSP

TCEA3

151

O75764
KKPKKRPNSPESTSS

TIRAP

31

P58753
SDASPPKTKTSPKLS

TOP2A

1351

P11388
RSKLLPSDSPSTPKT

WEE2

101

P0C1S8
PTPPATLKSTKASSK

PPIP5K2

1191

O43314
SPKHTSPLIISPKKS

TOGARAM1

826

Q9Y4F4
KKTSTPSPQPSKRAL

SMC5

6

Q8IY18
SLPKTKLSLPGSSKS

TRIP12

271

Q14669
KLSLPGSSKSETSKP

TRIP12

276

Q14669
LSPSPSLRKSSKSPK

ZC3H13

206

Q5T200
SLRKSSKSPKRKSSP

ZC3H13

211

Q5T200