Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionaspartic-type endopeptidase activity

ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-18 ERVK-19 ERVK-25

7.67e-10371047GO:0004190
GeneOntologyMolecularFunctionaspartic-type peptidase activity

ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-18 ERVK-19 ERVK-25

9.36e-10381047GO:0070001
GeneOntologyMolecularFunctionRNA-DNA hybrid ribonuclease activity

ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11

1.57e-09111045GO:0004523
GeneOntologyMolecularFunctionRNA-directed DNA polymerase activity

ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11

6.71e-09141045GO:0003964
GeneOntologyMolecularFunctionRNA stem-loop binding

ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11

6.62e-08211045GO:0035613
GeneOntologyMolecularFunctionRNA endonuclease activity, producing 5'-phosphomonoesters

ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11

1.33e-06371045GO:0016891
GeneOntologyMolecularFunctionDNA polymerase activity

ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11

1.52e-06381045GO:0034061
GeneOntologyMolecularFunctionendonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters

ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11

4.02e-06461045GO:0016893
GeneOntologyMolecularFunctionendopeptidase activity

ERVK-6 USP34 RHBDF1 RHBDF2 CELA2A ERVK-7 ERVK-10 ERVK-8 ERVK-18 ERVK-19 ERVK-25

1.50e-0543010411GO:0004175
GeneOntologyMolecularFunctionRNA endonuclease activity

ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11

5.77e-05791045GO:0004521
GeneOntologyMolecularFunctiongalactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity

B3GAT1 B3GAT2

8.03e-0531042GO:0015018
GeneOntologyMolecularFunctionnucleotidyltransferase activity

ERVK-6 ERVK-7 ERVK-10 PARP14 ERVK-8 ERVK-11

1.45e-041521046GO:0016779
GeneOntologyMolecularFunctionSUMO ligase activity

RGPD8 RGPD1 RGPD3

1.47e-04201043GO:0061665
GeneOntologyMolecularFunctionpeptidase activity

ERVK-6 USP34 RHBDF1 RHBDF2 CELA2A ERVK-7 ERVK-10 USP42 ERVK-8 ERVK-18 ERVK-19 ERVK-25

1.52e-0465410412GO:0008233
GeneOntologyMolecularFunctionlow-affinity IgG receptor activity

FCGR3A FCGR3B

1.60e-0441042GO:0019772
GeneOntologyMolecularFunctioncytoskeleton-nuclear membrane anchor activity

SYNE1 SYNE2

2.66e-0451042GO:0140444
GeneOntologyMolecularFunctionIgE receptor activity

FCGR3A FCGR3B

3.98e-0461042GO:0019767
GeneOntologyMolecularFunctionIgE binding

FCGR3A FCGR3B

5.55e-0471042GO:0019863
GeneOntologyMolecularFunctionIgG receptor activity

FCGR3A FCGR3B

5.55e-0471042GO:0019770
GeneOntologyMolecularFunctionRNA nuclease activity

ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11

7.30e-041361045GO:0004540
GeneOntologyMolecularFunctionendonuclease activity

ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11

7.30e-041361045GO:0004519
GeneOntologyMolecularFunctionSUMO transferase activity

RGPD8 RGPD1 RGPD3

8.65e-04361043GO:0019789
GeneOntologyMolecularFunctionnuclease activity

ERVK-6 ERVK-7 ERVK-10 ERVK-8 PLSCR2 ERVK-11

1.33e-032311046GO:0004518
GeneOntologyMolecularFunctionIgG binding

FCGR3A FCGR3B

1.43e-03111042GO:0019864
GeneOntologyMolecularFunctioncatalytic activity, acting on RNA

ERVK-6 TRMT10B ERVK-7 ERVK-10 DTWD1 ERVK-8 ERVK-11 CMTR2

1.52e-034171048GO:0140098
GeneOntologyMolecularFunctionimmune receptor activity

GFRAL FPR1 FCGR3A FCGR3B IL17RB

1.73e-031651045GO:0140375
GeneOntologyMolecularFunctionalcohol binding

CRABP1 OSBPL7 OSBPL6 OSBPL10

2.00e-031021044GO:0043178
GeneOntologyMolecularFunctionglycolipid binding

CLEC4F FCGR3A FCGR3B

2.12e-03491043GO:0051861
GeneOntologyMolecularFunctionpeptidyl-prolyl cis-trans isomerase activity

RGPD8 RGPD1 RGPD3

2.25e-03501043GO:0003755
GeneOntologyMolecularFunctionimmunoglobulin receptor activity

FCGR3A FCGR3B

2.35e-03141042GO:0019763
GeneOntologyMolecularFunctioncatalytic activity, acting on DNA

PMS1 ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11

2.50e-032621046GO:0140097
GeneOntologyMolecularFunctioncis-trans isomerase activity

RGPD8 RGPD1 RGPD3

2.66e-03531043GO:0016859
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor

RNLS LOXL2

3.07e-03161042GO:0016641
GeneOntologyMolecularFunctioncholesterol binding

OSBPL7 OSBPL6 OSBPL10

3.44e-03581043GO:0015485
GeneOntologyMolecularFunctionactin binding

FLNB MYLK SYNE1 SPTBN1 ARPC1B DST SSH3 SYNE2

3.57e-034791048GO:0003779
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the CH-NH2 group of donors

RNLS LOXL2

4.80e-03201042GO:0016638
GeneOntologyMolecularFunctionlipid binding

FNBP1 CPNE8 CPNE9 SPTBN1 CRABP1 CLEC4F FCGR3A FCGR3B OSBPL7 OSBPL6 OSBPL10 MCOLN3

5.28e-0398810412GO:0008289
GeneOntologyBiologicalProcessDNA integration

ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11

3.34e-09131025GO:0015074
GeneOntologyBiologicalProcessNLS-bearing protein import into nucleus

RGPD8 RGPD1 RGPD3 RGPD5

2.57e-06201024GO:0006607
GeneOntologyBiologicalProcessDNA synthesis involved in DNA repair

ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11

3.87e-06481025GO:0000731
GeneOntologyBiologicalProcesspositive regulation of glucokinase activity

RGPD8 RGPD1 RGPD3

9.65e-0691023GO:0033133
GeneOntologyBiologicalProcesspositive regulation of hexokinase activity

RGPD8 RGPD1 RGPD3

1.37e-05101023GO:1903301
GeneOntologyBiologicalProcessperforin production

FCGR3A FCGR3B

2.42e-0521022GO:0035944
GeneOntologyBiologicalProcessregulation of glucokinase activity

RGPD8 RGPD1 RGPD3

3.24e-05131023GO:0033131
GeneOntologyBiologicalProcessregulation of hexokinase activity

RGPD8 RGPD1 RGPD3

4.11e-05141023GO:1903299
GeneOntologyBiologicalProcessRNA-templated DNA biosynthetic process

ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11

5.73e-05831025GO:0006278
GeneOntologyBiologicalProcessDNA-templated DNA replication

ERVK-6 WDR18 ERVK-7 ERVK-10 ERVK-8 ERVK-11

2.58e-041781026GO:0006261
GeneOntologyCellularComponentcytoplasmic periphery of the nuclear pore complex

RGPD8 RGPD1 RGPD3

6.58e-0681043GO:1990723
GeneOntologyCellularComponentnuclear pore cytoplasmic filaments

RGPD8 RGPD1 RGPD3

1.40e-05101043GO:0044614
GeneOntologyCellularComponentannulate lamellae

RGPD8 RGPD1 RGPD3

4.18e-05141043GO:0005642
GeneOntologyCellularComponentnuclear pore nuclear basket

RGPD8 RGPD1 RGPD3

9.25e-05181043GO:0044615
GeneOntologyCellularComponentnuclear inclusion body

RGPD8 RGPD1 RGPD3

1.28e-04201043GO:0042405
GeneOntologyCellularComponentFc-gamma receptor III complex

FCGR3A FCGR3B

1.46e-0441042GO:0033001
GeneOntologyCellularComponentSUMO ligase complex

RGPD8 RGPD1 RGPD3

1.49e-04211043GO:0106068
GeneOntologyCellularComponentperinuclear endoplasmic reticulum

DST OSBPL7 OSBPL6

3.98e-04291043GO:0097038
GeneOntologyCellularComponentmicrotubule organizing center attachment site

SYNE1 SYNE2

1.31e-03111042GO:0034992
GeneOntologyCellularComponentmeiotic nuclear membrane microtubule tethering complex

SYNE1 SYNE2

1.31e-03111042GO:0034993
GeneOntologyCellularComponentnuclear membrane protein complex

SYNE1 SYNE2

1.31e-03111042GO:0106083
GeneOntologyCellularComponentnuclear membrane microtubule tethering complex

SYNE1 SYNE2

1.31e-03111042GO:0106094
GeneOntologyCellularComponentFc receptor complex

FCGR3A FCGR3B

1.57e-03121042GO:0032997
GeneOntologyCellularComponentnuclear pore

RGPD8 RGPD1 RGPD3 RGPD5

1.63e-031011044GO:0005643
GeneOntologyCellularComponentnuclear membrane

RGPD8 SYNE1 RGPD1 RGPD3 SYNE2 OSBPL7 OSBPL6

1.81e-033491047GO:0031965
GeneOntologyCellularComponentnuclear envelope

RGPD8 SYNE1 RGPD1 DST RGPD3 SYNE2 OSBPL7 OSBPL6 RGPD5

1.92e-035601049GO:0005635
GeneOntologyCellularComponentnuclear outer membrane-endoplasmic reticulum membrane network

RHBDF1 RGPD8 RHBDF2 SYNE1 RGPD1 KSR1 DST ARL6IP1 PGAP2 RGPD3 SYNE2 OSBPL7 OSBPL6 B3GAT1 PHTF1

2.33e-03132710415GO:0042175
DomainActinin_actin-bd_CS

FLNB SYNE1 SPTBN1 DST SYNE2

9.58e-0823955IPR001589
DomainACTININ_2

FLNB SYNE1 SPTBN1 DST SYNE2

9.58e-0823955PS00020
DomainACTININ_1

FLNB SYNE1 SPTBN1 DST SYNE2

9.58e-0823955PS00019
DomainGrip

RGPD8 RGPD1 RGPD3 RGPD5

2.02e-0711954SM00755
DomainGRIP

RGPD8 RGPD1 RGPD3 RGPD5

2.02e-0711954PF01465
DomainRan_BP1

RGPD8 RGPD1 RGPD3 RGPD5

3.01e-0712954PF00638
DomainGRIP_dom

RGPD8 RGPD1 RGPD3 RGPD5

3.01e-0712954IPR000237
DomainGRIP

RGPD8 RGPD1 RGPD3 RGPD5

3.01e-0712954PS50913
DomainRANBD1

RGPD8 RGPD1 RGPD3 RGPD5

3.01e-0712954PS50196
DomainRanBD

RGPD8 RGPD1 RGPD3 RGPD5

4.34e-0713954SM00160
DomainRan_bind_dom

RGPD8 RGPD1 RGPD3 RGPD5

4.34e-0713954IPR000156
DomainGCC2_Rab_bind

RGPD8 RGPD1 RGPD3

4.40e-067953IPR032023
DomainRab_bind

RGPD8 RGPD1 RGPD3

4.40e-067953PF16704
DomainSpectrin

SYNE1 SPTBN1 DST SYNE2

5.16e-0623954PF00435
DomainSpectrin_repeat

SYNE1 SPTBN1 DST SYNE2

1.35e-0529954IPR002017
Domain-

RGPD8 RGPD1 RGPD3

1.49e-05109531.10.220.60
DomainCH

FLNB SYNE1 SPTBN1 DST SYNE2

1.99e-0565955SM00033
DomainSpectrin/alpha-actinin

SYNE1 SPTBN1 DST SYNE2

2.03e-0532954IPR018159
DomainSPEC

SYNE1 SPTBN1 DST SYNE2

2.03e-0532954SM00150
DomainRhomboid_SP

RHBDF1 RHBDF2

2.56e-052952IPR022241
DomainRhomboid_SP

RHBDF1 RHBDF2

2.56e-052952PF12595
DomainOxysterol-bd

OSBPL7 OSBPL6 OSBPL10

2.71e-0512953IPR000648
DomainOxysterol-bd_CS

OSBPL7 OSBPL6 OSBPL10

2.71e-0512953IPR018494
DomainOxysterol_BP

OSBPL7 OSBPL6 OSBPL10

2.71e-0512953PF01237
DomainOSBP

OSBPL7 OSBPL6 OSBPL10

2.71e-0512953PS01013
DomainCH

FLNB SYNE1 SPTBN1 DST SYNE2

2.85e-0570955PF00307
Domain-

FLNB SYNE1 SPTBN1 DST SYNE2

3.06e-05719551.10.418.10
DomainCH

FLNB SYNE1 SPTBN1 DST SYNE2

3.50e-0573955PS50021
DomainCH-domain

FLNB SYNE1 SPTBN1 DST SYNE2

3.99e-0575955IPR001715
DomainGlyco_trans_43

B3GAT1 B3GAT2

7.65e-053952IPR005027
DomainGlyco_transf_43

B3GAT1 B3GAT2

7.65e-053952PF03360
DomainKASH

SYNE1 SYNE2

1.53e-044952PF10541
DomainKASH

SYNE1 SYNE2

1.53e-044952IPR012315
DomainKASH

SYNE1 SYNE2

1.53e-044952PS51049
DomainKASH

SYNE1 SYNE2

1.53e-044952SM01249
DomainPeptidase_S54_rhomboid

RHBDF1 RHBDF2

7.03e-048952IPR002610
DomainCopine

CPNE8 CPNE9

9.00e-049952PF07002
DomainRhomboid

RHBDF1 RHBDF2

9.00e-049952PF01694
DomainPeptidase_S54_rhomboid_dom

RHBDF1 RHBDF2

9.00e-049952IPR022764
DomainCopine

CPNE8 CPNE9

9.00e-049952IPR010734
Domain-

RHBDF1 RHBDF2

9.00e-0499521.20.1540.10
DomainPH_dom-like

RGPD8 SPTBN1 RGPD1 RGPD3 OSBPL7 OSBPL6 OSBPL10 RGPD5

1.48e-03426958IPR011993
DomainWD_REPEATS_1

WDR18 ARPC1B ELP2 PHIP RIC1 WDR24

2.96e-03278956PS00678
DomainWD_REPEATS_2

WDR18 ARPC1B ELP2 PHIP RIC1 WDR24

3.02e-03279956PS50082
DomainWD_REPEATS_REGION

WDR18 ARPC1B ELP2 PHIP RIC1 WDR24

3.02e-03279956PS50294
Domain-

RGPD8 SPTBN1 RGPD1 RGPD3 OSBPL7 OSBPL6 OSBPL10

3.81e-033919572.30.29.30
DomainWD40_repeat_dom

WDR18 ARPC1B ELP2 PHIP RIC1 WDR24

4.09e-03297956IPR017986
DomainIg_2

FCRL2 FCGR3A FCGR3B

6.13e-0373953PF13895
DomainTPR-like_helical_dom

RGPD8 RGPD1 TRRAP RGPD3 RGPD5

6.76e-03233955IPR011990
Domain-

WDR18 ARPC1B ELP2 PHIP RIC1 WDR24

7.08e-033339562.130.10.10
DomainTPR-contain_dom

RGPD8 RGPD1 RGPD3 RGPD5

7.23e-03150954IPR013026
DomainWD40/YVTN_repeat-like_dom

WDR18 ARPC1B ELP2 PHIP RIC1 WDR24

7.28e-03335956IPR015943
DomainC2_dom

CPNE8 CPNE9 OSBPL6 SMURF2

9.83e-03164954IPR000008
DomainTPR_REGION

RGPD8 RGPD1 RGPD3 RGPD5

1.00e-02165954PS50293
DomainTPR

RGPD8 RGPD1 RGPD3 RGPD5

1.00e-02165954PS50005
PathwayBIOCARTA_RANBP2_PATHWAY

HDAC5 RGPD8 RGPD1 RGPD3

1.53e-0618694MM1549
PathwayREACTOME_TRANSPORT_OF_THE_SLBP_DEPENDANT_MATURE_MRNA

RGPD8 RGPD1 NCBP1 RGPD3

5.62e-0543694MM14609
PathwayREACTOME_TRANSPORT_OF_MATURE_MRNAS_DERIVED_FROM_INTRONLESS_TRANSCRIPTS

RGPD8 RGPD1 NCBP1 RGPD3

1.02e-0450694MM14610
Pubmed

Quantitation of HERV-K env gene expression and splicing in human breast cancer.

ERVK-6 ERVK-7 ERVK-18 ERVK-19

3.91e-105105412629516
Pubmed

A revised nomenclature for transcribed human endogenous retroviral loci.

ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-18 ERVK-19 ERVK-25 ERVK-11

4.73e-1094105821542922
Pubmed

Complex genomic rearrangements lead to novel primate gene function.

RGPD8 RGPD1 RGPD3 RGPD5

2.73e-097105415710750
Pubmed

Genome-wide screening, cloning, chromosomal assignment, and expression of full-length human endogenous retrovirus type K.

ERVK-6 ERVK-18 ERVK-19

2.67e-083105310516026
Pubmed

Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression.

RGPD8 SYNE1 WDR18 RNF213 NCBP1 LSM12 GLYR1 PAEP RGPD3 PHIP

7.10e-083321051025693804
Pubmed

Many human endogenous retrovirus K (HERV-K) proviruses are unique to humans.

ERVK-6 ERVK-7 ERVK-10

1.07e-074105310469592
Pubmed

Human endogenous retrovirus K10: expression of Gag protein and detection of antibodies in patients with seminomas.

ERVK-6 ERVK-10 ERVK-19

1.07e-07410537983737
Pubmed

Expression patterns of transcribed human endogenous retrovirus HERV-K(HML-2) loci in human tissues and the need for a HERV Transcriptome Project.

ERVK-10 ERVK-18 ERVK-25 ERVK-11

2.32e-0718105418664271
Pubmed

Nup358, a nucleoporin, functions as a key determinant of the nuclear pore complex structure remodeling during skeletal myogenesis.

RGPD8 RGPD1 RGPD3

9.28e-077105321205196
Pubmed

Haploinsufficiency of RanBP2 is neuroprotective against light-elicited and age-dependent degeneration of photoreceptor neurons.

RGPD8 RGPD1 RGPD3

9.28e-077105318949001
Pubmed

Selective impairment of a subset of Ran-GTP-binding domains of ran-binding protein 2 (Ranbp2) suffices to recapitulate the degeneration of the retinal pigment epithelium (RPE) triggered by Ranbp2 ablation.

RGPD8 RGPD1 RGPD3

9.28e-077105325187515
Pubmed

Interconversion of red opsin isoforms by the cyclophilin-related chaperone protein Ran-binding protein 2.

RGPD8 RGPD1 RGPD3

9.28e-07710539037092
Pubmed

Localization of the Ran-GTP binding protein RanBP2 at the cytoplasmic side of the nuclear pore complex.

RGPD8 RGPD1 RGPD3

9.28e-07710538603673
Pubmed

Uncoupling phototoxicity-elicited neural dysmorphology and death by insidious function and selective impairment of Ran-binding protein 2 (Ranbp2).

RGPD8 RGPD1 RGPD3

9.28e-077105326632511
Pubmed

Differential loss of prolyl isomerase or chaperone activity of Ran-binding protein 2 (Ranbp2) unveils distinct physiological roles of its cyclophilin domain in proteostasis.

RGPD8 RGPD1 RGPD3

9.28e-077105324403063
Pubmed

Distinct and atypical intrinsic and extrinsic cell death pathways between photoreceptor cell types upon specific ablation of Ranbp2 in cone photoreceptors.

RGPD8 RGPD1 RGPD3

9.28e-077105323818861
Pubmed

Genomic organization, expression, and localization of murine Ran-binding protein 2 (RanBP2) gene.

RGPD8 RGPD1 RGPD3

9.28e-077105311353387
Pubmed

Microglial activation in an amyotrophic lateral sclerosis-like model caused by Ranbp2 loss and nucleocytoplasmic transport impairment in retinal ganglion neurons.

RGPD8 RGPD1 RGPD3

9.28e-077105330944974
Pubmed

Nucleoporin Nup358 drives the differentiation of myeloid-biased multipotent progenitors by modulating HDAC3 nuclear translocation.

RGPD8 RGPD1 RGPD3

9.28e-077105338838144
Pubmed

Kinesin-1 and mitochondrial motility control by discrimination of structurally equivalent but distinct subdomains in Ran-GTP-binding domains of Ran-binding protein 2.

RGPD8 RGPD1 RGPD3

9.28e-077105323536549
Pubmed

Retina-specifically expressed novel subtypes of bovine cyclophilin.

RGPD8 RGPD1 RGPD3

9.28e-07710537559465
Pubmed

Mst1, RanBP2 and eIF4G are new markers for in vivo PI3K activation in murine and human prostate.

RGPD8 RGPD1 RGPD3

9.28e-077105317372272
Pubmed

Proteostatic Remodeling of Small Heat Shock Chaperones─Crystallins by Ran-Binding Protein 2─and the Peptidyl-Prolyl cis-trans Isomerase and Chaperone Activities of Its Cyclophilin Domain.

RGPD8 RGPD1 RGPD3

9.28e-077105338657106
Pubmed

Identification of RanBP2- and kinesin-mediated transport pathways with restricted neuronal and subcellular localization.

RGPD8 RGPD1 RGPD3

9.28e-077105312191015
Pubmed

Ranbp2 haploinsufficiency mediates distinct cellular and biochemical phenotypes in brain and retinal dopaminergic and glia cells elicited by the Parkinsonian neurotoxin, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).

RGPD8 RGPD1 RGPD3

9.28e-077105322821000
Pubmed

Neuroprotection resulting from insufficiency of RANBP2 is associated with the modulation of protein and lipid homeostasis of functionally diverse but linked pathways in response to oxidative stress.

RGPD8 RGPD1 RGPD3

9.28e-077105320682751
Pubmed

The distribution of phosphorylated SR proteins and alternative splicing are regulated by RANBP2.

RGPD8 RGPD1 RGPD3

1.48e-068105322262462
Pubmed

The nucleoporin RanBP2 tethers the cAMP effector Epac1 and inhibits its catalytic activity.

RGPD8 RGPD1 RGPD3

1.48e-068105321670213
Pubmed

Zap70 and downstream RanBP2 are required for the exact timing of the meiotic cell cycle in oocytes.

RGPD8 RGPD1 RGPD3

1.48e-068105328745977
Pubmed

Critical role of RanBP2-mediated SUMOylation of Small Heterodimer Partner in maintaining bile acid homeostasis.

RGPD8 RGPD1 RGPD3

1.48e-068105327412403
Pubmed

Mice lacking Ran binding protein 1 are viable and show male infertility.

RGPD8 RGPD1 RGPD3

1.48e-068105321310149
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

FLNB MYLK RGPD8 SYNE1 SPTBN1 BIVM RGPD1 NCBP1 CHUK DST UMODL1 PAEP RGPD3 SYNE2 SMURF2 PHTF1 RGPD5

1.49e-0614421051735575683
Pubmed

Resolution of sister centromeres requires RanBP2-mediated SUMOylation of topoisomerase IIalpha.

RGPD8 RGPD1 RGPD3

2.22e-069105318394993
Pubmed

The docking of kinesins, KIF5B and KIF5C, to Ran-binding protein 2 (RanBP2) is mediated via a novel RanBP2 domain.

RGPD8 RGPD1 RGPD3

2.22e-069105311553612
Pubmed

The zinc finger cluster domain of RanBP2 is a specific docking site for the nuclear export factor, exportin-1.

RGPD8 RGPD1 RGPD3

2.22e-069105310601307
Pubmed

The cyclophilin-like domain mediates the association of Ran-binding protein 2 with subunits of the 19 S regulatory complex of the proteasome.

RGPD8 RGPD1 RGPD3

2.22e-06910539733766
Pubmed

Loss of Ranbp2 in motoneurons causes disruption of nucleocytoplasmic and chemokine signaling, proteostasis of hnRNPH3 and Mmp28, and development of amyotrophic lateral sclerosis-like syndromes.

RGPD8 RGPD1 RGPD3

2.22e-069105328100513
Pubmed

Impairments in age-dependent ubiquitin proteostasis and structural integrity of selective neurons by uncoupling Ran GTPase from the Ran-binding domain 3 of Ranbp2 and identification of novel mitochondrial isoforms of ubiquitin-conjugating enzyme E2I (ubc9) and Ranbp2.

RGPD8 RGPD1 RGPD3

2.22e-069105328877029
Pubmed

Association of the kinesin-binding domain of RanBP2 to KIF5B and KIF5C determines mitochondria localization and function.

RGPD8 RGPD1 RGPD3

2.22e-069105317887960
Pubmed

Cyclophilin-related protein RanBP2 acts as chaperone for red/green opsin.

RGPD8 RGPD1 RGPD3

3.16e-061010538857542
Pubmed

The RanBP2/RanGAP1*SUMO1/Ubc9 SUMO E3 ligase is a disassembly machine for Crm1-dependent nuclear export complexes.

RGPD8 RGPD1 RGPD3

3.16e-0610105327160050
Pubmed

Parkin ubiquitinates and promotes the degradation of RanBP2.

RGPD8 RGPD1 RGPD3

3.16e-0610105316332688
Pubmed

Ran-dependent docking of importin-beta to RanBP2/Nup358 filaments is essential for protein import and cell viability.

RGPD8 RGPD1 RGPD3

3.16e-0610105321859863
Pubmed

An Rtn4/Nogo-A-interacting micropeptide modulates synaptic plasticity with age.

RGPD8 RGPD1 RGPD3

4.33e-0611105335771867
Pubmed

The OSBP-related protein family in humans.

OSBPL7 OSBPL6 OSBPL10

4.33e-0611105311483621
Pubmed

RanBP2 modulates Cox11 and hexokinase I activities and haploinsufficiency of RanBP2 causes deficits in glucose metabolism.

RGPD8 RGPD1 RGPD3

4.33e-0611105317069463
Pubmed

T-cell receptor (TCR) signaling promotes the assembly of RanBP2/RanGAP1-SUMO1/Ubc9 nuclear pore subcomplex via PKC-θ-mediated phosphorylation of RanGAP1.

RGPD8 RGPD1 RGPD3

4.33e-0611105334110283
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

USP34 FLNB SPTBN1 WDR18 NCBP1 TRRAP DST GLYR1 SYNE2 PYGB PHIP

4.75e-066531051122586326
Pubmed

The first avian Ig-like Fc receptor family member combines features of mammalian FcR and FCRL.

FCRL2 FCGR3A FCGR3B

5.77e-0612105317273841
Pubmed

A family of 12 human genes containing oxysterol-binding domains.

OSBPL7 OSBPL6 OSBPL10

5.77e-0612105311735225
Pubmed

An oxysterol-binding protein family identified in the mouse.

OSBPL7 OSBPL6 OSBPL10

5.77e-0612105312215260
Pubmed

Genomewide screening for fusogenic human endogenous retrovirus envelopes identifies syncytin 2, a gene conserved on primate evolution.

ERVK-6 ERVK-8 ERVK-19

5.77e-0612105314557543
Pubmed

Ankyrin-G induces nucleoporin Nup358 to associate with the axon initial segment of neurons.

RGPD8 RGPD1 RGPD3

7.48e-0613105331427429
Pubmed

Multiple novel nesprin-1 and nesprin-2 variants act as versatile tissue-specific intracellular scaffolds.

SYNE1 SYNE2

9.03e-062105222768332
Pubmed

Human Fc gamma RIII: cloning, expression, and identification of the chromosomal locus of two Fc receptors for IgG.

FCGR3A FCGR3B

9.03e-06210522521732
Pubmed

FCGR Genetic Variation in Two Populations From Ecuador Highlands-Extensive Copy-Number Variation, Distinctive Distribution of Functional Polymorphisms, and a Novel, Locally Common, Chimeric FCGR3B/A (CD16B/A) Gene.

FCGR3A FCGR3B

9.03e-062105234108956
Pubmed

Single-cell analyses identify dysfunctional CD16+ CD8 T cells in smokers.

FCGR3A FCGR3B

9.03e-062105233163982
Pubmed

Attenuation of Excess TNF-α Release in Crohn's Disease by Silencing of iRHOMs 1/2 and the Restoration of TGF-β Mediated Immunosuppression Through Modulation of TACE Trafficking.

RHBDF1 RHBDF2

9.03e-062105235585977
Pubmed

Nesprins: a novel family of spectrin-repeat-containing proteins that localize to the nuclear membrane in multiple tissues.

SYNE1 SYNE2

9.03e-062105211792814
Pubmed

The human natural killer cytotoxic cell line NK-92, once armed with a murine CD16 receptor, represents a convenient cellular tool for the screening of mouse mAbs according to their ADCC potential.

FCGR3A FCGR3B

9.03e-062105223770975
Pubmed

Nesprin-1 and nesprin-2 regulate endothelial cell shape and migration.

SYNE1 SYNE2

9.03e-062105224931616
Pubmed

Association study of copy number variants in FCGR3A and FCGR3B gene with risk of ankylosing spondylitis in a Chinese population.

FCGR3A FCGR3B

9.03e-062105226494566
Pubmed

Mammalian iRhoms have distinct physiological functions including an essential role in TACE regulation.

RHBDF1 RHBDF2

9.03e-062105223969955
Pubmed

Confirmation of association of FCGR3B but not FCGR3A copy number with susceptibility to autoantibody positive rheumatoid arthritis.

FCGR3A FCGR3B

9.03e-062105222290871
Pubmed

FcÎł receptor IIIb polymorphism and use of glucocorticoids at baseline are associated with infusion reactions to infliximab in patients with rheumatoid arthritis.

FCGR3A FCGR3B

9.03e-062105220980704
Pubmed

Nucleotide sequence of a new Fc gamma receptor IIIB allele that codes for a neutrophil antigen.

FCGR3A FCGR3B

9.03e-062105211034564
Pubmed

Hypoxia inducible factor-2alpha stabilization and maxi-K+ channel beta1-subunit gene repression by hypoxia in cardiac myocytes: role in preconditioning.

KCNMB1 EPAS1

9.03e-062105219461047
Pubmed

Expression of human endogenous retrovirus type K envelope glycoprotein in insect and mammalian cells.

ERVK-6 ERVK-19

9.03e-06210529060628
Pubmed

Impact of allele copy number of polymorphisms in FCGR3A and FCGR3B genes on susceptibility to ulcerative colitis.

FCGR3A FCGR3B

9.03e-062105223917248
Pubmed

Evolutionary relationships within a subgroup of HERV-K-related human endogenous retroviruses.

ERVK-6 ERVK-19

9.03e-06210529460924
Pubmed

Evidence for gene recombination in FCGR3 gene variants.

FCGR3A FCGR3B

9.03e-062105219320901
Pubmed

Syne-1 and Syne-2 play crucial roles in myonuclear anchorage and motor neuron innervation.

SYNE1 SYNE2

9.03e-062105217267447
Pubmed

Genes adapt to outsmart gene-targeting strategies in mutant mouse strains by skipping exons to reinitiate transcription and translation.

RHBDF1 RHBDF2

9.03e-062105232646486
Pubmed

Association analysis of copy numbers of FC-gamma receptor genes for rheumatoid arthritis and other immune-mediated phenotypes.

FCGR3A FCGR3B

9.03e-062105225966632
Pubmed

The Fc gamma receptor of natural killer cells is a phospholipid-linked membrane protein.

FCGR3A FCGR3B

9.03e-06210522967436
Pubmed

Nesprins: tissue-specific expression of epsilon and other short isoforms.

SYNE1 SYNE2

9.03e-062105224718612
Pubmed

Separate promoters from proximal and medial control regions contribute to the natural killer cell-specific transcription of the human FcgammaRIII-A (CD16-A) receptor gene.

FCGR3A FCGR3B

9.03e-06210528940055
Pubmed

Targeted ablation of nesprin 1 and nesprin 2 from murine myocardium results in cardiomyopathy, altered nuclear morphology and inhibition of the biomechanical gene response.

SYNE1 SYNE2

9.03e-062105224586179
Pubmed

FCGR3A and FCGR3B copy number variations are risk factors for sarcoidosis.

FCGR3A FCGR3B

9.03e-062105227059607
Pubmed

Genome-wide association study of bipolar disorder in Canadian and UK populations corroborates disease loci including SYNE1 and CSMD1.

SYNE1 CSMD1

9.03e-062105224387768
Pubmed

Nesprin-1 and -2 are involved in the pathogenesis of Emery Dreifuss muscular dystrophy and are critical for nuclear envelope integrity.

SYNE1 SYNE2

9.03e-062105217761684
Pubmed

Nesprin-1-alpha2 associates with kinesin at myotube outer nuclear membranes, but is restricted to neuromuscular junction nuclei in adult muscle.

SYNE1 SYNE2

9.03e-062105231578382
Pubmed

Distributions of glucuronyltransferases, GlcAT-P and GlcAT-S, and their target substrate, the HNK-1 carbohydrate epitope in the adult mouse brain with or without a targeted deletion of the GlcAT-P gene.

B3GAT1 B3GAT2

9.03e-062105217935701
Pubmed

Low copy numbers of FCGR3A and FCGR3B associated with Chinese patients with SLE and AASV.

FCGR3A FCGR3B

9.03e-062105228355982
Pubmed

Association of iRhom1 and iRhom2 expression with prognosis in patients with cervical cancer and possible signaling pathways.

RHBDF1 RHBDF2

9.03e-062105231661139
Pubmed

Association of FCGR3A and FCGR3B copy number variations with systemic lupus erythematosus and rheumatoid arthritis in Taiwanese patients.

FCGR3A FCGR3B

9.03e-062105225154742
Pubmed

The human low affinity immunoglobulin G Fc receptor III-A and III-B genes. Molecular characterization of the promoter regions.

FCGR3A FCGR3B

9.03e-06210527836402
Pubmed

Identification of an ADAM17 cleavage region in human CD16 (FcÎłRIII) and the engineering of a non-cleavable version of the receptor in NK cells.

FCGR3A FCGR3B

9.03e-062105225816339
Pubmed

A human immunoglobulin G receptor exists in both polypeptide-anchored and phosphatidylinositol-glycan-anchored forms.

FCGR3A FCGR3B

9.03e-06210522525780
Pubmed

FcgammaRIII expression on cultured human keratinocytes and upregulation by interferon-gamma.

FCGR3A FCGR3B

9.03e-062105212445195
Pubmed

Alternative membrane forms of Fc gamma RIII(CD16) on human natural killer cells and neutrophils. Cell type-specific expression of two genes that differ in single nucleotide substitutions.

FCGR3A FCGR3B

9.03e-06210522526846
Pubmed

A Sulfated Glycosaminoglycan Linkage Region is a Novel Type of Human Natural Killer-1 (HNK-1) Epitope Expressed on Aggrecan in Perineuronal Nets.

B3GAT1 B3GAT2

9.03e-062105226659409
Pubmed

Interferon-alpha-induced endogenous superantigen. a model linking environment and autoimmunity.

ERVK-6 ERVK-18

9.03e-062105211672541
Pubmed

The loss of the CD16 B73.1/Leu11c epitope occurring in some primary immunodeficiency diseases is not associated with the FcgammaRIIIa-48L/R/H polymorphism.

FCGR3A FCGR3B

9.03e-062105220664961
Pubmed

B lymphocyte depletion by CD20 monoclonal antibody prevents diabetes in nonobese diabetic mice despite isotype-specific differences in Fc gamma R effector functions.

FCGR3A FCGR3B

9.03e-062105218292508
Pubmed

Limited expression of nuclear pore membrane glycoprotein 210 in cell lines and tissues suggests cell-type specific nuclear pores in metazoans.

RGPD8 RGPD1 RGPD3

1.18e-0515105314697343
Pubmed

The macrophage IRF8/IRF1 regulome is required for protection against infections and is associated with chronic inflammation.

PARP14 FCGR3A FCGR3B

2.11e-0518105327001747
Pubmed

Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.

SYNE1 RNF213 PARP14 TRRAP DST SYNE2

2.31e-05187105626460568
Pubmed

Association of Fcgamma receptor IIa genotype with chronic periodontitis in Caucasians.

FCGR3A FCGR3B

2.70e-053105215152814
Pubmed

Catchup: a mouse model for imaging-based tracking and modulation of neutrophil granulocytes.

FCGR3A FCGR3B

2.70e-053105225775045
InteractionRGPD4 interactions

RGPD8 RGPD1 RGPD3 RGPD5

3.90e-06221004int:RGPD4
InteractionRGPD2 interactions

RGPD8 RGPD1 RGPD3 RGPD5

9.17e-06271004int:RGPD2
InteractionHSPB8 interactions

USP34 RGPD8 RHBDF2 OSBPL10 PYGB KNL1 RGPD5

2.40e-051721007int:HSPB8
GeneFamilyOxysterol binding proteins|Pleckstrin homology domain containing

OSBPL7 OSBPL6 OSBPL10

1.19e-0512703670
GeneFamilyBeta-1,3-glucuronyltransferases

B3GAT1 B3GAT2

4.42e-053702423
GeneFamilySpectrin repeat containing nuclear envelope family

SYNE1 SYNE2

8.82e-0547021252
GeneFamilyCopines

CPNE8 CPNE9

5.23e-049702829
GeneFamilyTetratricopeptide repeat domain containing|Bardet-Biedl syndrome associated|BBSome

RGPD8 RGPD1 RGPD3 RGPD5

1.03e-03115704769
GeneFamilyRhomboid family

RHBDF1 RHBDF2

1.30e-0314702926
GeneFamilyWD repeat domain containing

WDR18 ARPC1B ELP2 PHIP WDR24

3.46e-03262705362
GeneFamilyADAM metallopeptidase domain containing|CD molecules

FCRL2 ICAM3 FCGR3A FCGR3B B3GAT1 LY75

4.18e-03394706471
GeneFamilyImmunoglobulin like domain containing

FCRL2 ICAM3 FCGR3A FCGR3B

6.67e-03193704594
ToppCell343B-Fibroblasts-Fibroblast-G|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

MYLK SPTBN1 DST PGAP2 TMEM37 BMPER MCOLN3

2.73e-07199977212e89d097753790061310373a1fafba773488b6
ToppCell343B-Fibroblasts-Fibroblast-G-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

MYLK SPTBN1 DST PGAP2 TMEM37 BMPER MCOLN3

2.73e-0719997714b676aa289c0578a37be32cec3ea285c79d97cc
ToppCellLPS_IL1RA-Endothelial-Endothelial|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

FLNB SPTBN1 RNF213 PARP14 DST SYNE2 EPAS1

2.83e-0720097772ea9882a8ed26fa1534aeb6ba0d1897dccc20c5
ToppCellLPS_IL1RA-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

USP34 FLNB SPTBN1 RNF213 DST SYNE2 EPAS1

2.83e-07200977dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCellLPS_IL1RA-Endothelial|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

FLNB SPTBN1 RNF213 PARP14 DST SYNE2 EPAS1

2.83e-072009775c092b2ecc081b5d04476c56333c338cd89ab984
ToppCellLPS_IL1RA-Endothelial-Endothelial-Activated_Alv_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

MYLK SPTBN1 RNF213 PARP14 DST SYNE2 EPAS1

2.83e-0720097779e51afb57ca38aacebd0298e5e727b55c0cfff9
ToppCellPBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_2|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

LRRN1 SYNE1 FPR1 RGPD1 ZNF792 FCGR3B

1.39e-06160976bb1bb3673059768c0ea0160d29fff127f3a4ecb4
ToppCellPBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_2|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LRRN1 SYNE1 FPR1 RGPD1 ZNF792 FCGR3B

1.39e-0616097676f49b8b4450fa8acd36326bfa36a5d1f4bd95fb
ToppCellCOVID-19_Severe-gd_T|COVID-19_Severe / Disease condition and Cell class

SYNE1 RNF213 FCGR3A FCGR3B SYNE2 B3GAT1

3.13e-06184976791f1bcb954aadc63d4117c400537d036f68734d
ToppCellCOVID-19-Heart-EC_2|Heart / Disease (COVID-19 only), tissue and cell type

MAGI1 FLNB CPNE8 PARP14 SYNE2 EPAS1

3.43e-0618797640ffc06a3e3251d9b12da390210d3e045af7537a
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51|PBMC_fresh-frozen / Compartment, severity and other cell annotations on 10x 3' data (130k)

SYNE1 RNF213 NCBP1 FCGR3B SYNE2 RGPD5

3.65e-061899760e8d1be3c406d1a393e18faccfe89116a8f82bcf
ToppCell(5)_Fibroblasts-(5)_Fibroblast-C_(Myofibroblast)|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)

MYLK SPTBN1 DST TMEM37 BMPER MCOLN3

3.76e-0619097671e112dfb8c3190fe0286b45a046ea789eb6a8db
ToppCellRV-10._Endothelium_II|World / Chamber and Cluster_Paper

FLNB SPTBN1 PARP14 SYNE2 BMPER EPAS1

4.12e-061939762531266bc57339d4e2b22a88817008e32b8c1598
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MAGI1 KANSL1L SYNE1 RNF213 SYNE2 OSBPL10

4.24e-06194976e577d9e88390b36b5a09b97fe1026089892275a3
ToppCellIPF-Multiplet-Multiplet|IPF / Disease state, Lineage and Cell class

MAGI1 RNLS SYNE1 SPTBN1 SYNE2 OSBPL6

4.37e-06195976fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCellIPF-Multiplet|IPF / Disease state, Lineage and Cell class

MAGI1 RNLS SYNE1 SPTBN1 SYNE2 OSBPL6

4.37e-06195976eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCellCOVID-19-Heart-EC_1|Heart / Disease (COVID-19 only), tissue and cell type

MAGI1 CPNE8 SYNE1 PARP14 SYNE2 EPAS1

4.37e-0619597650a193475db1bb1e05b8590225a553688c372c14
ToppCell367C-Fibroblasts-Fibroblast-C_(Myofibroblast)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

SPTBN1 DST TMEM37 BMPER MMD MCOLN3

4.50e-061969766730743cf088c419ccc2d28765769fc09d3ba6a7
ToppCell367C-Fibroblasts-Fibroblast-C_(Myofibroblast)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

SPTBN1 DST TMEM37 BMPER MMD MCOLN3

4.50e-0619697621dab89f3699037138a9c7a0e4dc98739a9fad9c
ToppCellsevere_COVID-19-NK|severe_COVID-19 / disease group, cell group and cell class (v2)

SYNE1 RNF213 FCGR3A SYNE2 OSBPL7 B3GAT1

4.77e-061989767f51e37516f717e424190e6584f1c74d357e2da4
ToppCell10x3'2.3-week_17-19-Myeloid_neutrophil-granulo-neutrophil|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

SYNE1 FPR1 ICAM3 FCGR3A FCGR3B SYNE2

4.77e-0619897682f6ac18c3a6487f03579b5c247844f1c115c2be
ToppCellsystemic_lupus_erythematosus-flare|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

URI1 SYNE1 RNF213 C1GALT1 ARL6IP1 SYNE2

4.77e-061989764c93ee921d56132d80832d8e94563f32ccf13bbc
ToppCellhealthy_donor-Lymphocytic-ILC-NK_cell|healthy_donor / Disease condition, Lineage, Cell class and subclass

SYNE1 RNF213 FCGR3A FCGR3B SYNE2 B3GAT1

4.77e-06198976d7053a898e04478c577381085f615edaad3cdc5b
ToppCell10x3'2.3-week_17-19-Myeloid_neutrophil-granulo|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

SYNE1 FPR1 ICAM3 FCGR3A FCGR3B SYNE2

4.77e-06198976f870e398e996c1f28c8462d87b18f71b20c71011
ToppCell10x5'v1-week_14-16-Myeloid_neutrophil-granulo-neutrophil-neutrophil|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

SYNE1 FPR1 ICAM3 FCGR3A FCGR3B SYNE2

4.77e-06198976e76061e66f6d60f5735962aa7777dda8958caed9
ToppCellhealthy_donor-Lymphocytic-ILC|healthy_donor / Disease condition, Lineage, Cell class and subclass

SYNE1 RNF213 FCGR3A FCGR3B SYNE2 B3GAT1

4.77e-06198976aa33be29e26f1b8facfc894413099083ae3bbb1b
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

USP34 SYNE1 RNF213 PARP14 SYNE2 RGPD5

4.91e-06199976f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell10x5'v1-week_14-16-Myeloid_neutrophil-granulo|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

SYNE1 FPR1 ICAM3 FCGR3A FCGR3B SYNE2

4.91e-061999765919933c4b842b98fc98685dc8c72c8dd32c6ea3
ToppCellCOVID_non-vent-Lymphocytic-ILC|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

SYNE1 RNF213 FCGR3A FCGR3B SYNE2 B3GAT1

4.91e-06199976df4f7d5be099e3e6054f3b812ccf70251664e4c0
ToppCellCOVID_vent-Lymphocytic-ILC|COVID_vent / Disease condition, Lineage, Cell class and subclass

SYNE1 RNF213 FCGR3A FCGR3B SYNE2 B3GAT1

4.91e-06199976e3ff7fa1b1de1aaf6b46cdf49afa95bad457728a
ToppCellCOVID_non-vent-Lymphocytic-ILC-NK_cell|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

SYNE1 RNF213 FCGR3A FCGR3B SYNE2 B3GAT1

4.91e-06199976ed35d747f11f6ea6a5cb7061057f0a98d9e0db99
ToppCellPBMC-Control-Lymphocyte-T/NK-NK_cell-NK|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SYNE1 RNF213 FCGR3A FCGR3B SYNE2 B3GAT1

4.91e-061999764820f5bcd7bc34c2ebf6a3422cc8eb383a3b5a4e
ToppCellPBMC-Control-Lymphocyte-T/NK-NK_cell|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SYNE1 RNF213 FCGR3A FCGR3B SYNE2 B3GAT1

4.91e-06199976eb05ccae5187e4701bbbe6d714a6d2808fbcf306
ToppCellPBMC-Control-Lymphocyte-T/NK-NK_cell|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

SYNE1 RNF213 FCGR3A FCGR3B SYNE2 B3GAT1

4.91e-0619997610c8729b779073c3bf808e85958d59147f0be5c5
ToppCellPBMC-Control-Lymphocyte-T/NK-NK_cell-NK-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SYNE1 RNF213 FCGR3A FCGR3B SYNE2 B3GAT1

4.91e-06199976867fd292f3879982422e840e087bfdb3b21a8715
ToppCellPBMC-Control-Lymphocyte-T/NK-NK_cell-NK-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SYNE1 RNF213 FCGR3A FCGR3B SYNE2 B3GAT1

4.91e-061999765e9fe852a70546c9d235414a2c26ca3e67ba6eb9
ToppCellControl-Lymphoid_T/NK-NK|Control / Disease group, lineage and cell class

SYNE1 RNF213 FCGR3A FCGR3B SYNE2 B3GAT1

4.91e-0619997694b2693a8378b9b2c58c6aebb2c6658d75b2e3de
ToppCellCOVID_vent-Lymphocytic-ILC-NK_cell|COVID_vent / Disease condition, Lineage, Cell class and subclass

SYNE1 RNF213 FCGR3A FCGR3B SYNE2 B3GAT1

4.91e-061999765f914962e2572b0c6372465b81b7496fa663d93c
ToppCell10x5'v1-week_14-16-Myeloid_neutrophil-granulo-neutrophil|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

SYNE1 FPR1 ICAM3 FCGR3A FCGR3B SYNE2

4.91e-06199976caf2e050b21e7a16ce4e51b3f135debd06810231
ToppCellPBMC-Control-Lymphocyte-T/NK-NK_cell-NK|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

SYNE1 RNF213 FCGR3A FCGR3B SYNE2 B3GAT1

4.91e-06199976d2c9fb69e5ef75778a1652da293fcf8cfa7ecfcc
ToppCellLPS_IL1RA-Endothelial-Endothelial-Activated_Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

FLNB SPTBN1 RNF213 PARP14 SMURF2 EPAS1

5.05e-062009762d07237022b409c4fac6fcf99b68c8affb3007cd
ToppCellLPS_only-Endothelial|LPS_only / Treatment groups by lineage, cell group, cell type

FLNB SPTBN1 PARP14 DST SYNE2 EPAS1

5.05e-0620097681e76508c9050d533853d5fd2f3097b27613d836
ToppCellControl-Control-Lymphocyte-T/NK-NK|Control / Disease, condition lineage and cell class

SYNE1 RNF213 FCGR3A FCGR3B SYNE2 B3GAT1

5.05e-06200976c64c27dbf4df42ca2ad2bd94b50fab87b4050ef3
ToppCellControl_saline-Endothelial-Endothelial-Artery|Control_saline / Treatment groups by lineage, cell group, cell type

FNBP1 FLNB CPNE8 DST SYNE2 EPAS1

5.05e-0620097665b71f1e8da5c3750fcd0a2e66d9ef3125a3f78a
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-T/NK-NK_activated|COVID-19_Mild / Disease, condition lineage and cell class

SYNE1 RNF213 FCGR3A FCGR3B SYNE2 B3GAT1

5.05e-062009762281debd86e5d92e8fe0397aec9ef670800f7471
ToppCellLPS_anti-TNF-Endothelial-Endothelial-Artery|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

FLNB CPNE8 DST SYNE2 CSMD1 EPAS1

5.05e-06200976b1ff8d61b567f85006d6d20093f9c803b6d34674
ToppCellLPS_only-Endothelial-Endothelial|LPS_only / Treatment groups by lineage, cell group, cell type

FLNB SPTBN1 PARP14 DST SYNE2 EPAS1

5.05e-062009764bb609a284d4e6066f17470a1736076aa4a1f84c
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

LRRN1 ABCA12 FPR1 FCGR3B CSMD1

1.88e-05149975c5eedb54ef2e0f131aa6730612c921bc19479632
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_granulocytic|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

LRRN1 ABCA12 FPR1 FCGR3B CSMD1

1.88e-05149975a22417286de8606f0cc94f86b70bce17aeefb9c2
ToppCellImmune_cells-Neutrophils|World / Lineage and Cell class

SYNE1 FPR1 FCGR3A FCGR3B LY75

2.00e-05151975056301bedb4285e797250b55d79ee1790a17516d
ToppCellBronchial-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MYLK RGPD8 OSBPL6 KCNMB1 MCOLN3

2.57e-051599757cda111bb98f1241989e49d490bdf51a712ea589
ToppCellfacs-Heart-LA-18m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FPR1 CLEC4F FCGR3A FCGR3B TMEM37

3.06e-05165975be7e18d798e81e4b0f3080054aa222c6913e350b
ToppCellfacs-Heart-LA-18m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FPR1 CLEC4F FCGR3A FCGR3B TMEM37

3.06e-05165975941a5b95164eaea47c3e6376e358f94c15b98312
ToppCellCOVID-19_Mild-PLT_2|World / Disease Group and Platelet Clusters

RGPD8 TBC1D32 RGPD3 OSBPL10 RIC1

3.44e-051699756abfdc8b437f19c03b408bedc245059d28c6ba6a
ToppCellControl-Epithelial_cells-ECM-high_epithelial|Control / group, cell type (main and fine annotations)

MAGI1 FLNB SPTBN1 DST EPAS1

3.53e-05170975e2023d66e70983c87dacbd6181d3426488d1fc57
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FPR1 CLEC4F FCGR3A FCGR3B OSBPL10

3.95e-05174975dc4298c1d9359f7e37454e9451f889017227d5cf
ToppCell10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD8_cytotoxic-D|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CELA2A ZNF623 ZFAND4 NMT2 MCOLN3

4.06e-05175975a3f8c54c77bce9b035a4835945ab341909be4946
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c05-ZNF683|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

SYNE1 RNF213 FCGR3A SYNE2 B3GAT1

4.17e-051769755914e7635474e7cf24d446bdb1423bc0807ee9c6
ToppCell3'_v3-blood-Mast-Mast_cells|blood / Manually curated celltypes from each tissue

SPTBN1 BIVM SSH3 EPAS1 RIC1

4.17e-05176975b9da3deaf62622d47eb30b6be7548253eee95597
ToppCell5'-Adult-Appendix-Hematopoietic-T_cells-CX3CR1+_CD8_Tmem|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SYNE1 RGPD1 FCGR3A SYNE2 B3GAT1

4.17e-051769756b06da40eb97ea2db09f3a769494738b3e5fe3fa
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SYNE1 RNF213 FCGR3A FCGR3B SYNE2

4.28e-05177975d3e6c768b88b7906f3c7fdd00ba20842212c14b1
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Endothelial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPTBN1 PARP14 SYNE2 PLSCR2 EPAS1

4.28e-05177975ca5a30b3e7bcfdd8de01ceaf7449735b5cd503af
ToppCelldroplet-Lung-LUNG-30m-Myeloid-Interstitial_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FPR1 CLEC4F FCGR3A FCGR3B TMEM37

4.28e-0517797543883b65b1e03043a24fc40c84c50bac81960c12
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SYNE1 RNF213 FCGR3A FCGR3B SYNE2

4.28e-05177975f8f101c772c043636bedd6b2ec81409b1d2599bf
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Endothelial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPTBN1 PARP14 SYNE2 PLSCR2 EPAS1

4.28e-05177975f471f7747d6e8db7546899019af9508f48a14f89
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Endothelial-endothelial_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPTBN1 PARP14 SYNE2 PLSCR2 EPAS1

4.28e-05177975cd0684b876c2a7d5fe7e2773e8e25bb61ecbc795
ToppCelldroplet-Lung-LUNG-30m-Myeloid-lung_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FPR1 CLEC4F FCGR3A FCGR3B TMEM37

4.28e-051779759de6a82b7fb72d20361947f7ac95bb1fa73fc2ff
ToppCellCOVID-19_Mild-Lymphoid_T/NK-NK_activated|COVID-19_Mild / Disease group, lineage and cell class

SYNE1 RNF213 FCGR3A FCGR3B SYNE2

4.28e-051779756978a22fef40c8b455342373abe7593f5ede0fa4
ToppCellPND14-Immune-Immune_Myeloid-Monocytic-Macrophage-AM|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FPR1 FCGR3A LY75 MCOLN3 KNL1

4.28e-0517797567cc3a6461db5e0678f96b18224aeb83ad34b0f4
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

SYNE1 RNF213 FCGR3A FCGR3B SYNE2

4.28e-05177975936ab2b180a052387124f68d0c7f41c0b164e748
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SYNE1 RNF213 FCGR3A FCGR3B SYNE2

4.28e-05177975d5aeda113afaa2425874394610344570c9078478
ToppCelldroplet-Limb_Muscle-MUSCLE-30m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYNE1 PARP14 ARL6IP1 SYNE2 PLSCR2

4.40e-0517897501dafd19de04eff459253eaa9a35debf8f3deedf
ToppCellCOVID-19-Heart-EC_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

MAGI1 FLNB CPNE8 SYNE2 EPAS1

4.52e-051799752a53d94f6c30bf887dfe88f1693ea057218c852d
ToppCell(05)_Ciliated-(4)_1wkpi|(05)_Ciliated / shred by cell type and Timepoint

USP34 CPNE8 ARPC1B LOXL2 KNL1

4.64e-0518097585fc9b164147b28545e2397d32302eea03ef6346
ToppCellsevere-Myeloid-Eosinophils|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

FLNB SYNE1 SYNE2 EPAS1 IL17RB

4.64e-05180975ac03812b1409435c55d323a7516deeac82bd3509
ToppCellCOVID-19_Mild-gd_T|COVID-19_Mild / Disease condition and Cell class

SYNE1 RNF213 FCGR3A FCGR3B SYNE2

5.02e-05183975f593a89b0aa8fffdfa403769916facfd30358521
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells-B_cells_L.1.5.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FNBP1 FCRL2 ICAM3 PARP14 OSBPL10

5.28e-05185975e913c64f9b4873443d88dce270f0b7b6d1b4cbce
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FNBP1 FCRL2 ICAM3 PARP14 OSBPL10

5.42e-051869751a1e5d85a5ad90afee234c12a9b54a5e93a8a2f2
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-B_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FNBP1 FCRL2 ICAM3 PARP14 OSBPL10

5.42e-05186975f1366638edaecad5cad6367440f4c693513bed7e
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_I-A|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

RHBDF2 ARPC1B FCGR3A KCNMB1 PLSCR2

5.70e-0518897548dcbb424771a2f839d65b0c429ef01ad3479a4a
ToppCellCOPD-Endothelial-VE_Capillary_A|Endothelial / Disease state, Lineage and Cell class

MYLK SYNE1 SPTBN1 OSBPL6 EPAS1

5.70e-051889751aa0e35b1c28ac847886fece16c3ef7fc6fcdd51
ToppCellCOVID-19-Heart-EC_1|COVID-19 / Disease (COVID-19 only), tissue and cell type

MAGI1 SYNE1 SPTBN1 SYNE2 EPAS1

5.85e-05189975fe49852ba15f948b384d6b4c258927c70b741357
ToppCellPND10|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYLK SPTBN1 DST AEBP2 EPAS1

5.99e-05190975d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_T_CD8-Tem/emra_CD8|lymph-node_spleen / Manually curated celltypes from each tissue

SYNE1 RNF213 FCGR3A SYNE2 B3GAT1

5.99e-0519097566d29f53f129fc18771f6214316a913eeaccd55e
ToppCellPBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_4|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

NCBP1 DTWD1 FCGR3B NMT2 KNL1

5.99e-051909753f0c7d130f66faea778fe567604edf1b4cdf85b3
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

USP34 SPTBN1 ARL6IP1 PGAP2 SYNE2

6.15e-0519197560c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

USP34 SPTBN1 ARL6IP1 PGAP2 SYNE2

6.15e-0519197509db184cb90fe282a14474d7217068c58092c6f8
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

USP34 SPTBN1 ARL6IP1 PGAP2 SYNE2

6.15e-05191975973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNB LRRN1 DST LOXL2 MCOLN3

6.30e-051929755b7093d5af5ae7b0e6d3a464cc56272440ecedad
ToppCellPBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_4|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

NCBP1 DTWD1 FCGR3B NMT2 KNL1

6.30e-05192975c09dcc73ff9c3855a0f3d7bfa0d5c99c09a117f2
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_T-CytoT_GZMH+-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SYNE1 RNF213 FCGR3A SYNE2 B3GAT1

6.46e-05193975d66cbb8c71bdc57faecb74a16fe3f34cb0b33228
ToppCelldroplet-Fat-Mat-18m-Endothelial|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYLK SPTBN1 DST KCNMB1 EPAS1

6.46e-0519397554024a373e42e1c0bcc327dc084564b83b63a9d4
ToppCelldroplet-Fat-Mat-18m-Endothelial-endothelial_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYLK SPTBN1 DST KCNMB1 EPAS1

6.46e-0519397581d908594d2983ba7e7c1ec25afdde4315d9690e
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_T-CytoT_GZMH+|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SYNE1 RNF213 FCGR3A SYNE2 B3GAT1

6.46e-05193975c1d9c2436503791350086a503d6b98c5c69f44ae
ToppCell3'-GW_trimst-1-LargeIntestine-Hematopoietic-Myeloid-Monocytes|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FPR1 ICAM3 ARPC1B FCGR3A FCGR3B

6.46e-05193975db26b79dfe9c48388f6b64dceb21073d104ab504
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

RHBDF1 MYLK DST BMPER MCOLN3

6.61e-05194975e93de9428c986b8943fc169258847c650cfab0e5
ToppCell368C-Fibroblasts-Fibroblast-G-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

MYLK DST PGAP2 TMEM37 MCOLN3

6.61e-05194975d9eec28fa7b255c0ec023276dd955f1e276e7159
ToppCellcontrol-Myeloid-Neutrophils_2|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

FPR1 RNF213 PARP14 FCGR3A FCGR3B

6.61e-05194975267e213e8efe53aadfe553a2ca010a0e3b4b8939
ToppCell368C-Fibroblasts-Fibroblast-G|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

MYLK DST PGAP2 TMEM37 MCOLN3

6.61e-05194975e4d7e9709ce42d4610e44d3445927eefbcbb9eff
ToppCellBronchus_Control_(B.)-Epithelial-TX-AT2-2|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

ZXDA PLSCR2 B3GAT2 IL17RB RIC1

6.61e-051949755bfc26668fa8f109f2ebc0d5fd98ab5bd219e62c
DrugFnllp

FPR1 FCGR3A FCGR3B PYGB

3.26e-0714994CID000119508
Diseaselevel of low affinity immunoglobulin gamma Fc region receptor III-A in blood serum

FCGR3A FCGR3B

9.83e-062932OBA_2040305
DiseaseLupus Vasculitis, Central Nervous System

FCGR3A FCGR3B

2.94e-053932C0752332
DiseaseLupus Meningoencephalitis

FCGR3A FCGR3B

2.94e-053932C0752334
DiseaseNeuropsychiatric Systemic Lupus Erythematosus

FCGR3A FCGR3B

2.94e-053932C0752335
DiseaseFEV/FEC ratio

USP34 RNLS FPR1 C1GALT1 CRABP1 DST FCGR3A FCGR3B SYNE2 AEBP2 KCNMB1 CSMD1 CCDC171 SMURF2

2.99e-0512289314EFO_0004713
DiseaseAutosomal dominant Emery-Dreifuss muscular dystrophy

SYNE1 SYNE2

5.87e-054932cv:CN293514
DiseaseAutosomal Recessive Emery-Dreifuss Muscular Dystrophy

SYNE1 SYNE2

9.77e-055932C1450051
DiseaseAutosomal Dominant Emery-Dreifuss Muscular Dystrophy (disorder)

SYNE1 SYNE2

9.77e-055932C0410190
DiseaseEmery-Dreifuss muscular dystrophy

SYNE1 SYNE2

1.46e-046932cv:C0410189
DiseaseMuscular Dystrophy, Emery-Dreifuss

SYNE1 SYNE2

1.46e-046932C0410189
Diseaselow affinity immunoglobulin gamma Fc region receptor II-a/b measurement

FCGR3A FCGR3B

2.04e-047932EFO_0008211
DiseaseX-Linked Emery-Dreifuss Muscular Dystrophy

SYNE1 SYNE2

2.04e-047932C0751337
Diseaseplexin-B2 measurement

FCGR3A FCGR3B

3.49e-049932EFO_0021867
Diseaseresponse to carboplatin, response to antineoplastic agent

FLNB CSMD1

4.35e-0410932GO_0097327, GO_0097328
Diseaseaspartate aminotransferase measurement

MAGI1 FLNB RNF213 C1GALT1 FCGR3A FCGR3B OSBPL6 CSMD1 LY75 PHIP

5.64e-049049310EFO_0004736
Diseasemonokine induced by gamma interferon measurement

UMODL1 B3GAT2 PHTF1

5.99e-0452933EFO_0008236
DiseaseEmery-Dreifuss muscular dystrophy (implicated_via_orthology)

SYNE1 SYNE2

6.35e-0412932DOID:11726 (implicated_via_orthology)
Diseaselow affinity immunoglobulin gamma Fc region receptor III-B measurement

FCGR3A FCGR3B

8.72e-0414932EFO_0008212
DiseasePROSTATE CANCER, HEREDITARY, 1

RNLS B3GAT1 KNL1

9.11e-0460933C4722327
DiseaseIdiopathic pulmonary arterial hypertension

HDAC5 EPAS1

1.15e-0316932C3203102
Diseaseinterstitial lung disease

CRABP1 CSMD1 EPAS1

1.25e-0367933EFO_0004244
Diseaselow affinity immunoglobulin gamma Fc region receptor II-a measurement

FCGR3A FCGR3B

1.30e-0317932EFO_0021969
Diseaseserum IgG glycosylation measurement

MAGI1 CPNE8 CRABP1 UMODL1 OSBPL7 CSMD1 EPAS1

1.35e-03523937EFO_0005193
DiseaseProstate cancer, familial

RNLS B3GAT1 KNL1

1.37e-0369933C2931456
Diseasebipolar disorder

LETM2 CPNE8 HDAC5 SYNE1 TLCD4 CMTR2 EPAS1

2.35e-03577937MONDO_0004985
Diseasecortical thickness

MAGI1 FLNB RNLS SPTBN1 C1GALT1 AP3M1 UMODL1 GLYR1 PYGB CCDC171

2.66e-0311139310EFO_0004840
Diseaselow affinity immunoglobulin gamma Fc region receptor II-b measurement

FCGR3A FCGR3B

2.81e-0325932EFO_0021970

Protein segments in the cluster

PeptideGeneStartEntry
QKSNLKVVLTECWAT

UMODL1

1146

Q5DID0
AANCTKILVWHTRTE

B3GAT1

301

Q9P2W7
RTVNLKSATWKVLHC

EPAS1

181

Q99814
WVNESERHQLKTKVV

AEBP2

461

Q6ZN18
SVRICLQDHKWSGQT

CSMD1

2716

Q96PZ7
WVLKHCERFLKQQQT

TBC1D32

1036

Q96NH3
RHLWKIISEEVQNKC

ABCA12

2426

Q86UK0
ISCHAWNKDRTQIAI

ARPC1B

11

O15143
EQIKAQESCWHRQKK

CCDC171

651

Q6TFL3
KTRNARAQCVGWHSK

ADGRF4

341

Q8IZF3
HVRKSVNAELCTQAW

CMTR2

101

Q8IYT2
HCKKWADIVTDLNTQ

BIVM

371

Q86UB2
KWTTEQQQRFHEICS

ARL6IP1

96

Q15041
SVSKIVVHKDWNSNQ

CELA2A

101

P08217
LEKHWKSVVSQSVCD

AP3M1

16

Q9Y2T2
VSQLCEDKHSQCKWV

TMEM37

111

Q8WXS4
KCRSLATWENENKIH

CRABP1

81

P29762
REQVLKVCANHWITT

RGPD5

1101

Q99666
REQVLKVCANHWITT

RGPD8

1101

O14715
SVENVWTTCRANKQK

RIC1

716

Q4ADV7
VWTQESKCHLIETNI

KCNMB1

46

Q16558
LHRWENNSCVEKKVL

PAEP

76

P09466
CILWRLTKKHTVSQE

PGAP2

161

Q9UHJ9
TLRKNVAVNCSTEWK

KANSL1L

356

A0AUZ9
TRLIQKLHTSTCWLQ

LETM2

71

Q2VYF4
QVSCSAWVTVHEKKS

MYLK

591

Q15746
LFQTIHKTIKDCKWQ

LSM12

116

Q3MHD2
QKKNHWTSRVHECTV

MAGI1

6

Q96QZ7
QWHCGVRVSSNKKLV

NMT2

211

O60551
IIKSHWKERKTCAAQ

NCBP1

321

Q09161
IRECKDWHVSGSIQK

MCOLN3

266

Q8TDD5
RHVKDKVVQTNCKNW

IHO1

346

Q8IYA8
CVLANNSHRAKWKVI

DST

911

Q03001
RQKEIWHLLKIACTQ

CHUK

646

O15111
QNHCRSEVILEKWQK

IL17RB

356

Q9NRM6
QICDKHWTAKNSRVV

LOXL2

216

Q9Y4K0
TFTRWCNEHLKCVNK

FLNB

21

O75369
QTWHPCLTKFTIKNQ

PLSCR2

196

Q9NRY7
STKSWLSQVCHVCQK

KSR1

351

Q8IVT5
HTVTVWNRTAEKCDL

GLYR1

291

Q49A26
DVTWKQAKDIVQHCT

HERVK_113

611

P63132
TLTWHSAKRECLKSN

LY75

1121

O60449
VEEKESWKKTCTTQH

KNL1

2206

Q8NG31
CSVWISNKTAKQHSL

TUBGCP2

656

Q9BSJ2
WNKVTTCIHNILSGR

OSBPL6

726

Q9BZF3
DVTWKQAKDIVQHCT

ERVK-7

611

P63135
DVTWKQAKDIVQHCT

ERVK-6

611

Q9BXR3
IVSWKKSHLRTVEHC

MMD

81

Q15546
LKWKDKTRHVLQCQA

ICAM3

411

P32942
VKQVWDSVCVKSVHT

PARP14

731

Q460N5
DVTWKQAKDIVQHCT

ERVK-18

611

Q9QC07
QREQVLKVCANHWIT

RGPD3

1101

A6NKT7
QKLKSWEFQTCHSTV

BMPER

561

Q8N8U9
QSKCWQRVTRKCHED

GFRAL

241

Q6UXV0
RKAQQHIETCWKQLE

FNBP1

121

Q96RU3
NNCTKVLVWHTRTEK

B3GAT2

291

Q9NPZ5
CHKTEVVKNTLNPVW

CPNE9

186

Q8IYJ1
SLKWTQAVHCARNIV

BCE1

56

O60756
RQKTWHKITDTCQTL

ADGRF2

136

Q8IZF7
LRCHSWKNTALHKVT

FCGR3B

126

O75015
HVKATWAQRCNKVLF

C1GALT1

106

Q9NS00
TNKITSVHSRIIWSC

ELP2

661

Q6IA86
WCKAETVTHRIRKQS

FCRL2

176

Q96LA5
TLEKVIEIQSKHWSC

HDAC5

1046

Q9UQL6
IEIQSKHWSCVQKFA

HDAC5

1051

Q9UQL6
LRCHSWKNTALHKVT

FCGR3A

126

P08637
VHNKAVIWQKSRVSD

PMS1

191

P54277
CHKTEVVKNTLNPVW

CPNE8

196

Q86YQ8
QVELKTRKTCFWRHQ

DTWD1

226

Q8N5C7
DCVIHWINSNKTNIR

LRRN1

376

Q6UXK5
KVTSCIHNVLSGQRW

OSBPL7

636

Q9BZF2
RDQVLKVCANHWITT

RGPD1

1086

P0DJD0
VTNCQERIQHWKKVD

URI1

41

O94763
EIVQKRTFTKWINSH

SYNE1

26

Q8NF91
EEKCQNTHKRWTQVN

SYNE2

5356

Q8WXH0
VWTQNHRTVSLAKKV

FPR1

131

P21462
DSTQKWQRKSIRHCS

RHBDF1

96

Q96CC6
WDVQSKQCIRTVALK

WDR18

296

Q9BV38
CEEKRLCVNTHVWTK

OSBPL10

546

Q9BXB5
HLECNETKSWIREKT

SPTBN1

961

Q01082
ILTASRQSHVWEQKV

SSH3

466

Q8TE77
KTQKISSCVLRWDNE

CAMKMT

201

Q7Z624
VKKSWHEAEQFCVSQ

CLEC4F

486

Q8N1N0
TWKLAKDIVQHCTQC

ERVK-25

611

P63136
TRLKHCTPDSNIVKW

SMURF2

641

Q9HAU4
HCSKIWSCRKRITVE

RNF213

4736

Q63HN8
SEKICLKWQQTHRVG

USP42

96

Q9H9J4
VCWKAFSQKSQLIIH

ZNF182

546

P17025
QSLLRTNKSCKHVVW

PHIP

106

Q8WWQ0
LNSQVKKTTTRWCHI

PHTF1

316

Q9UMS5
KKTTTRWCHIVRDSD

PHTF1

321

Q9UMS5
IATKCQKWRHSQVTN

RNLS

281

Q5VYX0
DVTWKQAKDIVQHCT

ERVK-10

611

P10266
DVTWKQAKDIVQHCT

ERVK-8

611

P63133
WEITKKTCAYTNHTV

PYGB

366

P11216
DVTWKQAKDIVQHCT

ERVK-11

611

Q9UQG0
KIEWNSRVVSTCHSL

TLCD4

46

Q96MV1
SKKHLQDVDTWKSRC

ZXDA

531

P98168
KSFNCNSSLIKHWRV

ZNF792

401

Q3KQV3
WTLKQAQLHCQASEK

SH2D4B

191

Q5SQS7
TWKQAKDIVQHCTQC

ERVK-19

616

Q9WJR5
LCKHCTTINIDSTWQ

USP34

81

Q70CQ2
HCVQTIASVARVKWR

WDR24

246

Q96S15
CSKNVQRKQRHWEKI

TRMT10B

61

Q6PF06
SRVEVWEKTSCSKQV

ZFAND4

126

Q86XD8
RGCKQVTVTHWKIQT

ZNF623

76

O75123
ITKWPICTEQARSNH

RHBDF2

571

Q6PJF5
QLCHISTTLAEKTWV

TRRAP

2616

Q9Y4A5
IALHWEINTQKISRC

ZNF7

211

P17097
FITVVNCKTWVKSHR

TAS2R4

26

Q9NYW5
NCKTWVKSHRISSSD

TAS2R4

31

Q9NYW5