Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	transcription coactivator activity	MED14 KMT2C ARID1B MAML2 BCL9 ARID1A SS18 CREBBP YAP1 EP300 SS18L1	1.18e-12	303	33	11	GO:0003713
GeneOntologyMolecularFunction	chromatin binding	FOXO1 ARID1B CHD7 CHD4 UPF1 ARID1A MBD5 NFAT5 CLOCK CREBBP YAP1 STAG2 EP300 SMAD3	3.41e-12	739	33	14	GO:0003682
GeneOntologyMolecularFunction	transcription coregulator activity	MED14 KMT2C ARID1B CHD4 MAML2 BCL9 ARID1A SS18 CREBBP YAP1 EP300 SS18L1	4.55e-11	562	33	12	GO:0003712
GeneOntologyMolecularFunction	molecular adaptor activity	MED14 KMT2C ARID1B CHD4 TAB1 MAML2 BCL9 ARID1A SS18 GCN1 CREBBP YAP1 EP300 SS18L1	9.98e-09	1356	33	14	GO:0060090
GeneOntologyMolecularFunction	transcription factor binding	MED14 FOXO1 TBX18 CHD4 ARID1A NFAT5 CLOCK CREBBP YAP1 EP300 SMAD3	1.85e-08	753	33	11	GO:0008134
GeneOntologyMolecularFunction	protein-macromolecule adaptor activity	MED14 KMT2C ARID1B CHD4 MAML2 BCL9 ARID1A SS18 CREBBP YAP1 EP300 SS18L1	1.59e-07	1160	33	12	GO:0030674
GeneOntologyMolecularFunction	chromatin DNA binding	FOXO1 CHD4 CLOCK CREBBP EP300 SMAD3	2.87e-07	167	33	6	GO:0031490
GeneOntologyMolecularFunction	transcription coactivator binding	FOXO1 CREBBP EP300 SMAD3	1.84e-06	54	33	4	GO:0001223
GeneOntologyMolecularFunction	peptide lactyltransferase (CoA-dependent) activity	CREBBP EP300	2.65e-06	2	33	2	GO:0120300
GeneOntologyMolecularFunction	histone H3K27 acetyltransferase activity	CREBBP EP300	2.65e-06	2	33	2	GO:0044017
GeneOntologyMolecularFunction	transcription coregulator binding	FOXO1 CHD4 CREBBP EP300 SMAD3	3.20e-06	140	33	5	GO:0001221
GeneOntologyMolecularFunction	DNA-binding transcription factor binding	MED14 TBX18 CHD4 ARID1A CREBBP YAP1 EP300 SMAD3	3.62e-06	582	33	8	GO:0140297
GeneOntologyMolecularFunction	RNA polymerase II-specific DNA-binding transcription factor binding	MED14 TBX18 CHD4 ARID1A CREBBP EP300 SMAD3	4.40e-06	417	33	7	GO:0061629
GeneOntologyMolecularFunction	histone H3K18 acetyltransferase activity	CREBBP EP300	7.94e-06	3	33	2	GO:0043993
GeneOntologyMolecularFunction	promoter-specific chromatin binding	FOXO1 CHD7 EP300 SMAD3	1.04e-05	83	33	4	GO:1990841
GeneOntologyMolecularFunction	SMAD binding	ZFYVE9 CREBBP EP300 SMAD3	1.19e-05	86	33	4	GO:0046332
GeneOntologyMolecularFunction	ATP-dependent chromatin remodeler activity	CHD7 CHD4 ARID1A	3.08e-05	37	33	3	GO:0140658
GeneOntologyMolecularFunction	bHLH transcription factor binding	CREBBP EP300 SMAD3	3.08e-05	37	33	3	GO:0043425
GeneOntologyMolecularFunction	beta-catenin binding	FOXO1 BCL9 EP300 SMAD3	4.44e-05	120	33	4	GO:0008013
GeneOntologyMolecularFunction	ATP-dependent activity, acting on DNA	CHD7 CHD4 UPF1 ARID1A	5.54e-05	127	33	4	GO:0008094
GeneOntologyMolecularFunction	histone acetyltransferase activity	CLOCK CREBBP EP300	8.11e-05	51	33	3	GO:0004402
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	FOXO1 TBX18 CHD7 USF3 NFAT5 CLOCK CREBBP YAP1 EP300 SMAD3	8.20e-05	1459	33	10	GO:0000977
GeneOntologyMolecularFunction	peptide-lysine-N-acetyltransferase activity	CLOCK CREBBP EP300	1.02e-04	55	33	3	GO:0061733
GeneOntologyMolecularFunction	peptide N-acetyltransferase activity	CLOCK CREBBP EP300	1.32e-04	60	33	3	GO:0034212
GeneOntologyMolecularFunction	nuclear receptor binding	MED14 ARID1A EP300 SMAD3	2.46e-04	187	33	4	GO:0016922
GeneOntologyMolecularFunction	histone H3 acetyltransferase activity	CREBBP EP300	2.74e-04	15	33	2	GO:0010484
GeneOntologyMolecularFunction	N-acetyltransferase activity	CLOCK CREBBP EP300	2.88e-04	78	33	3	GO:0008080
GeneOntologyMolecularFunction	nuclear glucocorticoid receptor binding	EP300 SMAD3	4.94e-04	20	33	2	GO:0035259
GeneOntologyMolecularFunction	histone modifying activity	KMT2C CLOCK CREBBP EP300	5.31e-04	229	33	4	GO:0140993
GeneOntologyMolecularFunction	peroxisome proliferator activated receptor binding	CREBBP EP300	5.45e-04	21	33	2	GO:0042975
GeneOntologyMolecularFunction	nucleosome binding	ARID1B CHD4 ARID1A	5.62e-04	98	33	3	GO:0031491
GeneOntologyMolecularFunction	N-acyltransferase activity	CLOCK CREBBP EP300	6.32e-04	102	33	3	GO:0016410
GeneOntologyMolecularFunction	acetyltransferase activity	CLOCK CREBBP EP300	6.68e-04	104	33	3	GO:0016407
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	FOXO1 TBX18 CHD7 NFAT5 CLOCK YAP1 EP300 SMAD3	7.59e-04	1244	33	8	GO:0000978
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	FOXO1 TBX18 CHD7 NFAT5 CLOCK YAP1 EP300 SMAD3	8.74e-04	1271	33	8	GO:0000987
GeneOntologyMolecularFunction	catalytic activity, acting on DNA	CHD7 CHD4 UPF1 ARID1A	8.79e-04	262	33	4	GO:0140097
GeneOntologyMolecularFunction	mitogen-activated protein kinase binding	TAB1 EP300	1.52e-03	35	33	2	GO:0051019
GeneOntologyMolecularFunction	DNA-binding transcription activator activity, RNA polymerase II-specific	FOXO1 USF3 NFAT5 CLOCK SMAD3	2.11e-03	560	33	5	GO:0001228
GeneOntologyMolecularFunction	DNA-binding transcription activator activity	FOXO1 USF3 NFAT5 CLOCK SMAD3	2.21e-03	566	33	5	GO:0001216
GeneOntologyMolecularFunction	helicase activity	CHD7 CHD4 UPF1	2.23e-03	158	33	3	GO:0004386
GeneOntologyMolecularFunction	nuclear receptor coactivator activity	MED14 SS18	4.56e-03	61	33	2	GO:0030374
GeneOntologyMolecularFunction	transcription corepressor activity	CHD4 CREBBP YAP1	6.30e-03	229	33	3	GO:0003714
GeneOntologyMolecularFunction	acyltransferase activity, transferring groups other than amino-acyl groups	CLOCK CREBBP EP300	7.01e-03	238	33	3	GO:0016747
GeneOntologyMolecularFunction	p53 binding	CREBBP EP300	7.17e-03	77	33	2	GO:0002039
GeneOntologyMolecularFunction	protein serine/threonine kinase activator activity	TAB1 GCN1	7.35e-03	78	33	2	GO:0043539
GeneOntologyMolecularFunction	damaged DNA binding	CREBBP EP300	8.48e-03	84	33	2	GO:0003684
GeneOntologyMolecularFunction	protein dimerization activity	TBX18 USF3 CLOCK OMG SMAD3 RAB11FIP2	1.30e-02	1205	33	6	GO:0046983
GeneOntologyMolecularFunction	zinc ion binding	CHD4 UPF1 CREBBP EP300 SMAD3	1.47e-02	891	33	5	GO:0008270
GeneOntologyMolecularFunction	DNA-binding transcription repressor activity	FOXO1 TBX18 SMAD3	1.64e-02	326	33	3	GO:0001217
GeneOntologyMolecularFunction	ATP-dependent activity	CHD7 CHD4 UPF1 ARID1A	1.79e-02	614	33	4	GO:0140657
GeneOntologyBiologicalProcess	positive regulation of transcription by RNA polymerase II	MED14 FOXO1 KMT2C CHD7 USF3 MAML2 BCL9 NFAT5 CLOCK SS18 CREBBP YAP1 EP300 SS18L1 SMAD3	1.36e-09	1390	34	15	GO:0045944
GeneOntologyBiologicalProcess	stem cell population maintenance	MED14 FOXO1 BCL9 ARID1A SS18 CREBBP YAP1 STAG2	3.79e-09	237	34	8	GO:0019827
GeneOntologyBiologicalProcess	maintenance of cell number	MED14 FOXO1 BCL9 ARID1A SS18 CREBBP YAP1 STAG2	4.46e-09	242	34	8	GO:0098727
GeneOntologyBiologicalProcess	protein-DNA complex organization	MED14 KMT2C ARID1B CHD7 CHD4 ARID1A NFAT5 CLOCK SS18 CREBBP EP300 SS18L1	3.18e-08	999	34	12	GO:0071824
GeneOntologyBiologicalProcess	chromatin organization	KMT2C ARID1B CHD7 CHD4 ARID1A NFAT5 CLOCK SS18 CREBBP EP300 SS18L1	1.12e-07	896	34	11	GO:0006325
GeneOntologyBiologicalProcess	chromatin remodeling	KMT2C ARID1B CHD7 CHD4 ARID1A NFAT5 CLOCK SS18 CREBBP EP300	2.02e-07	741	34	10	GO:0006338
GeneOntologyBiologicalProcess	DNA damage response	FOXO1 ARID1B CHD4 UPF1 ARID1A NFAT5 CLOCK CREBBP YAP1 EP300	2.13e-06	959	34	10	GO:0006974
GeneOntologyBiologicalProcess	protein acetylation	FOXO1 CLOCK CREBBP EP300	4.65e-06	68	34	4	GO:0006473
GeneOntologyBiologicalProcess	transforming growth factor beta receptor signaling pathway	TAB1 ZFYVE9 BCL9 CREBBP EP300 SMAD3	5.34e-06	276	34	6	GO:0007179
GeneOntologyBiologicalProcess	transcription initiation at RNA polymerase II promoter	MED14 FOXO1 ARID1B ARID1A EP300	1.27e-05	186	34	5	GO:0006367
GeneOntologyBiologicalProcess	regulation of transforming growth factor beta receptor signaling pathway	ZFYVE9 BCL9 CREBBP EP300 SMAD3	1.48e-05	192	34	5	GO:0017015
GeneOntologyBiologicalProcess	N-terminal peptidyl-lysine acetylation	CREBBP EP300	1.58e-05	4	34	2	GO:0018076
GeneOntologyBiologicalProcess	regulation of cellular response to transforming growth factor beta stimulus	ZFYVE9 BCL9 CREBBP EP300 SMAD3	1.60e-05	195	34	5	GO:1903844
GeneOntologyBiologicalProcess	cellular response to transforming growth factor beta stimulus	TAB1 ZFYVE9 BCL9 CREBBP EP300 SMAD3	1.64e-05	336	34	6	GO:0071560
GeneOntologyBiologicalProcess	response to transforming growth factor beta	TAB1 ZFYVE9 BCL9 CREBBP EP300 SMAD3	1.84e-05	343	34	6	GO:0071559
GeneOntologyBiologicalProcess	striated muscle tissue development	TBX18 CHD7 ARID1A YAP1 EP300 SMAD3	2.03e-05	349	34	6	GO:0014706
GeneOntologyBiologicalProcess	muscle tissue development	TBX18 CHD7 BCL9 ARID1A YAP1 EP300 SMAD3	2.91e-05	558	34	7	GO:0060537
GeneOntologyBiologicalProcess	protein acylation	FOXO1 CLOCK CREBBP EP300	2.92e-05	108	34	4	GO:0043543
GeneOntologyBiologicalProcess	DNA-templated transcription initiation	MED14 FOXO1 ARID1B ARID1A EP300	3.60e-05	231	34	5	GO:0006352
GeneOntologyBiologicalProcess	positive regulation of protein localization to nucleus	CREBBP YAP1 EP300 SMAD3	3.61e-05	114	34	4	GO:1900182
GeneOntologyBiologicalProcess	muscle structure development	TBX18 ARID1B CHD7 BCL9 ARID1A EP300 MBNL3 SMAD3	6.01e-05	858	34	8	GO:0061061
GeneOntologyBiologicalProcess	myoblast differentiation	ARID1B BCL9 ARID1A MBNL3	7.19e-05	136	34	4	GO:0045445
GeneOntologyBiologicalProcess	transforming growth factor beta receptor superfamily signaling pathway	TAB1 ZFYVE9 BCL9 CREBBP EP300 SMAD3	7.85e-05	445	34	6	GO:0141091
GeneOntologyBiologicalProcess	positive regulation of stem cell population maintenance	ARID1A SS18 YAP1	8.07e-05	51	34	3	GO:1902459
GeneOntologyBiologicalProcess	developmental growth	KMT2C CHD7 BCL9 MBD5 YAP1 OMG EP300 SMAD3	9.15e-05	911	34	8	GO:0048589
GeneOntologyBiologicalProcess	negative regulation of cardiac muscle hypertrophy in response to stress	FOXO1 SMAD3	9.43e-05	9	34	2	GO:1903243
GeneOntologyBiologicalProcess	enzyme-linked receptor protein signaling pathway	FOXO1 TAB1 ZFYVE9 BCL9 MBD5 SS18 CREBBP EP300 SMAD3	9.45e-05	1186	34	9	GO:0007167
GeneOntologyBiologicalProcess	negative regulation of cardiac muscle adaptation	FOXO1 SMAD3	1.18e-04	10	34	2	GO:0010616
GeneOntologyBiologicalProcess	cell surface receptor protein serine/threonine kinase signaling pathway	TAB1 ZFYVE9 BCL9 CREBBP EP300 SMAD3	1.22e-04	482	34	6	GO:0007178
GeneOntologyBiologicalProcess	face development	CHD7 CREBBP EP300	1.52e-04	63	34	3	GO:0060324
GeneOntologyBiologicalProcess	transcription initiation-coupled chromatin remodeling	ARID1B ARID1A EP300	1.67e-04	65	34	3	GO:0045815
GeneOntologyBiologicalProcess	Wnt signaling pathway	FOXO1 TBX18 BCL9 YAP1 SMAD3 AMOTL1	1.76e-04	516	34	6	GO:0016055
GeneOntologyBiologicalProcess	cardiac muscle tissue development	TBX18 CHD7 ARID1A YAP1 EP300	1.85e-04	327	34	5	GO:0048738
GeneOntologyBiologicalProcess	positive regulation of gene expression, epigenetic	ARID1B ARID1A EP300	1.91e-04	68	34	3	GO:0141137
GeneOntologyBiologicalProcess	regulation of protein localization to nucleus	CREBBP YAP1 EP300 SMAD3	1.95e-04	176	34	4	GO:1900180
GeneOntologyBiologicalProcess	heart development	TBX18 CHD7 TAB1 ARID1A YAP1 EP300 SMAD3	1.97e-04	757	34	7	GO:0007507
GeneOntologyBiologicalProcess	negative regulation of fat cell differentiation	FOXO1 YAP1 SMAD3	2.08e-04	70	34	3	GO:0045599
GeneOntologyBiologicalProcess	response to hormone	FOXO1 ARID1B ARID1A MBD5 CLOCK YAP1 EP300 SMAD3	2.31e-04	1042	34	8	GO:0009725
GeneOntologyBiologicalProcess	canonical Wnt signaling pathway	FOXO1 TBX18 BCL9 YAP1 SMAD3	2.34e-04	344	34	5	GO:0060070
GeneOntologyBiologicalProcess	regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	ZFYVE9 BCL9 CREBBP EP300 SMAD3	2.44e-04	347	34	5	GO:0090092
GeneOntologyBiologicalProcess	negative regulation of transcription by RNA polymerase II	FOXO1 TBX18 CHD4 ARID1A CREBBP YAP1 EP300 SMAD3	2.49e-04	1053	34	8	GO:0000122
GeneOntologyBiologicalProcess	embryonic organ morphogenesis	TBX18 CHD7 ARID1A YAP1 SMAD3	2.57e-04	351	34	5	GO:0048562
GeneOntologyBiologicalProcess	somitogenesis	TBX18 EP300 SMAD3	2.65e-04	76	34	3	GO:0001756
GeneOntologyBiologicalProcess	negative regulation of muscle adaptation	FOXO1 SMAD3	2.73e-04	15	34	2	GO:0014745
GeneOntologyBiologicalProcess	cellular response to radiation	CLOCK CREBBP YAP1 EP300	2.82e-04	194	34	4	GO:0071478
GeneOntologyBiologicalProcess	regulation of stem cell population maintenance	ARID1A SS18 YAP1	2.86e-04	78	34	3	GO:2000036
GeneOntologyBiologicalProcess	N-terminal protein amino acid acetylation	CREBBP EP300	3.12e-04	16	34	2	GO:0006474
GeneOntologyBiologicalProcess	regulation of cellular response to heat	CREBBP EP300	3.12e-04	16	34	2	GO:1900034
GeneOntologyBiologicalProcess	positive regulation of cell adhesion	TBX18 ARID1B ARID1A NFAT5 EP300 SMAD3	3.28e-04	579	34	6	GO:0045785
GeneOntologyBiologicalProcess	negative regulation of DNA-templated transcription	FOXO1 TBX18 CHD4 ARID1A CLOCK CREBBP YAP1 EP300 SMAD3	3.30e-04	1399	34	9	GO:0045892
GeneOntologyBiologicalProcess	cellular response to abiotic stimulus	NFAT5 CLOCK CREBBP YAP1 EP300	3.32e-04	371	34	5	GO:0071214
GeneOntologyBiologicalProcess	cellular response to environmental stimulus	NFAT5 CLOCK CREBBP YAP1 EP300	3.32e-04	371	34	5	GO:0104004
GeneOntologyBiologicalProcess	nuclear receptor-mediated glucocorticoid signaling pathway	ARID1A CLOCK	3.53e-04	17	34	2	GO:0042921
GeneOntologyBiologicalProcess	negative regulation of RNA biosynthetic process	FOXO1 TBX18 CHD4 ARID1A CLOCK CREBBP YAP1 EP300 SMAD3	3.55e-04	1413	34	9	GO:1902679
GeneOntologyBiologicalProcess	regulation of cellular response to stress	FOXO1 ARID1B ARID1A CREBBP OMG EP300	3.90e-04	598	34	6	GO:0080135
GeneOntologyBiologicalProcess	nuclear receptor-mediated corticosteroid signaling pathway	ARID1A CLOCK	3.97e-04	18	34	2	GO:0031958
GeneOntologyBiologicalProcess	circulatory system development	FOXO1 TBX18 CHD7 TAB1 ARID1A YAP1 EP300 SMAD3 AMOTL1	4.12e-04	1442	34	9	GO:0072359
GeneOntologyBiologicalProcess	positive regulation of cell-cell adhesion	TBX18 ARID1B ARID1A NFAT5 EP300	4.12e-04	389	34	5	GO:0022409
GeneOntologyBiologicalProcess	regulation of cardiac muscle hypertrophy in response to stress	FOXO1 SMAD3	4.43e-04	19	34	2	GO:1903242
GeneOntologyBiologicalProcess	regulation of myoblast differentiation	ARID1B ARID1A MBNL3	4.65e-04	92	34	3	GO:0045661
GeneOntologyBiologicalProcess	regulation of cardiac muscle adaptation	FOXO1 SMAD3	4.92e-04	20	34	2	GO:0010612
GeneOntologyBiologicalProcess	somite development	TBX18 EP300 SMAD3	4.95e-04	94	34	3	GO:0061053
GeneOntologyBiologicalProcess	positive regulation of double-strand break repair	ARID1B ARID1A CREBBP	5.11e-04	95	34	3	GO:2000781
GeneOntologyBiologicalProcess	regulation of cellular response to growth factor stimulus	ZFYVE9 BCL9 CREBBP EP300 SMAD3	5.36e-04	412	34	5	GO:0090287
GeneOntologyBiologicalProcess	regulation of cardiac muscle hypertrophy	FOXO1 EP300 SMAD3	5.43e-04	97	34	3	GO:0010611
GeneOntologyBiologicalProcess	chordate embryonic development	TBX18 CHD7 TAB1 ARID1A YAP1 EP300 SMAD3	5.86e-04	906	34	7	GO:0043009
GeneOntologyBiologicalProcess	regulation of developmental growth	CHD7 MBD5 YAP1 OMG EP300	5.91e-04	421	34	5	GO:0048638
GeneOntologyBiologicalProcess	regulation of muscle hypertrophy	FOXO1 EP300 SMAD3	5.93e-04	100	34	3	GO:0014743
GeneOntologyBiologicalProcess	stimulatory C-type lectin receptor signaling pathway	CREBBP EP300	6.53e-04	23	34	2	GO:0002223
GeneOntologyBiologicalProcess	cellular response to lectin	CREBBP EP300	6.53e-04	23	34	2	GO:1990858
GeneOntologyBiologicalProcess	response to lectin	CREBBP EP300	6.53e-04	23	34	2	GO:1990840
GeneOntologyBiologicalProcess	embryo development ending in birth or egg hatching	TBX18 CHD7 TAB1 ARID1A YAP1 EP300 SMAD3	6.80e-04	929	34	7	GO:0009792
GeneOntologyBiologicalProcess	paraxial mesoderm development	YAP1 SMAD3	7.12e-04	24	34	2	GO:0048339
GeneOntologyBiologicalProcess	innate immune response activating cell surface receptor signaling pathway	CREBBP EP300 RAB11FIP2	7.23e-04	107	34	3	GO:0002220
GeneOntologyBiologicalProcess	multicellular organism growth	KMT2C CHD7 MBD5 EP300	7.23e-04	249	34	4	GO:0035264
GeneOntologyBiologicalProcess	growth	KMT2C CHD7 BCL9 MBD5 YAP1 OMG EP300 SMAD3	7.24e-04	1235	34	8	GO:0040007
GeneOntologyBiologicalProcess	somatic stem cell population maintenance	MED14 BCL9 YAP1	7.42e-04	108	34	3	GO:0035019
GeneOntologyBiologicalProcess	neuronal stem cell population maintenance	FOXO1 SS18	8.36e-04	26	34	2	GO:0097150
GeneOntologyBiologicalProcess	positive regulation of DNA-binding transcription factor activity	CLOCK CREBBP EP300 SMAD3	8.62e-04	261	34	4	GO:0051091
GeneOntologyBiologicalProcess	animal organ morphogenesis	AMBN TBX18 CHD7 TAB1 ARID1A YAP1 EP300 SMAD3	8.65e-04	1269	34	8	GO:0009887
GeneOntologyBiologicalProcess	cellular response to nutrient levels	FOXO1 GCN1 CREBBP EP300	8.74e-04	262	34	4	GO:0031669
GeneOntologyBiologicalProcess	peptidyl-lysine acetylation	CREBBP EP300	9.71e-04	28	34	2	GO:0018394
GeneOntologyBiologicalProcess	embryonic morphogenesis	TBX18 CHD7 ARID1A CREBBP YAP1 SMAD3	9.82e-04	713	34	6	GO:0048598
GeneOntologyBiologicalProcess	regulation of nucleotide-excision repair	ARID1B ARID1A	1.04e-03	29	34	2	GO:2000819
GeneOntologyBiologicalProcess	N-terminal protein amino acid modification	CREBBP EP300	1.04e-03	29	34	2	GO:0031365
GeneOntologyBiologicalProcess	segmentation	TBX18 EP300 SMAD3	1.08e-03	123	34	3	GO:0035282
GeneOntologyBiologicalProcess	cellular response to hormone stimulus	FOXO1 ARID1B ARID1A MBD5 CLOCK EP300	1.09e-03	727	34	6	GO:0032870
GeneOntologyBiologicalProcess	positive regulation of response to external stimulus	TAB1 CLOCK CREBBP EP300 SMAD3 RAB11FIP2	1.17e-03	738	34	6	GO:0032103
GeneOntologyBiologicalProcess	regulation of canonical Wnt signaling pathway	FOXO1 TBX18 YAP1 SMAD3	1.19e-03	285	34	4	GO:0060828
GeneOntologyBiologicalProcess	fat cell differentiation	FOXO1 YAP1 EP300 SMAD3	1.29e-03	291	34	4	GO:0045444
GeneOntologyBiologicalProcess	regulation of muscle adaptation	FOXO1 EP300 SMAD3	1.36e-03	133	34	3	GO:0043502
GeneOntologyBiologicalProcess	response to abiotic stimulus	FOXO1 KMT2C NFAT5 CLOCK CREBBP YAP1 EP300 SMAD3	1.36e-03	1361	34	8	GO:0009628
GeneOntologyBiologicalProcess	negative regulation of miRNA metabolic process	EP300 SMAD3	1.43e-03	34	34	2	GO:2000629
GeneOntologyBiologicalProcess	nuclear receptor-mediated steroid hormone signaling pathway	ARID1A CLOCK EP300	1.44e-03	136	34	3	GO:0030518
GeneOntologyBiologicalProcess	positive regulation of cellular response to transforming growth factor beta stimulus	CREBBP EP300	1.52e-03	35	34	2	GO:1903846
GeneOntologyBiologicalProcess	positive regulation of transforming growth factor beta receptor signaling pathway	CREBBP EP300	1.52e-03	35	34	2	GO:0030511
GeneOntologyBiologicalProcess	regulation of growth	CHD7 MBD5 YAP1 OMG EP300 SMAD3	1.53e-03	777	34	6	GO:0040008
GeneOntologyBiologicalProcess	respiratory system development	CHD7 TAB1 YAP1 EP300	1.53e-03	305	34	4	GO:0060541
GeneOntologyBiologicalProcess	cardiac muscle hypertrophy	FOXO1 EP300 SMAD3	1.64e-03	142	34	3	GO:0003300
GeneOntologyCellularComponent	nuclear protein-containing complex	MED14 TBX18 KMT2C ARID1B CHD4 UPF1 BCL9 ARID1A CLOCK SS18 CREBBP YAP1 SS18L1 SMAD3 AMOTL1	9.97e-10	1377	34	15	GO:0140513
GeneOntologyCellularComponent	chromatin	FOXO1 TBX18 ARID1B CHD7 CHD4 UPF1 ARID1A NFAT5 CLOCK SS18 CREBBP STAG2 EP300 SS18L1 SMAD3	2.69e-09	1480	34	15	GO:0000785
GeneOntologyCellularComponent	transcription regulator complex	MED14 TBX18 CHD4 BCL9 NFAT5 CLOCK CREBBP YAP1 EP300 SMAD3	2.33e-08	596	34	10	GO:0005667
GeneOntologyCellularComponent	RNA polymerase II transcription regulator complex	MED14 CHD4 BCL9 CLOCK CREBBP YAP1 SMAD3	2.33e-07	272	34	7	GO:0090575
GeneOntologyCellularComponent	SWI/SNF superfamily-type complex	ARID1B CHD4 ARID1A SS18 SS18L1	4.60e-07	96	34	5	GO:0070603
GeneOntologyCellularComponent	npBAF complex	ARID1B ARID1A SS18	1.41e-06	14	34	3	GO:0071564
GeneOntologyCellularComponent	ATPase complex	ARID1B CHD4 ARID1A SS18 SS18L1	2.00e-06	129	34	5	GO:1904949
GeneOntologyCellularComponent	nBAF complex	ARID1B ARID1A SS18L1	2.17e-06	16	34	3	GO:0071565
GeneOntologyCellularComponent	SWI/SNF complex	ARID1B ARID1A SS18	1.55e-05	30	34	3	GO:0016514
GeneOntologyCellularComponent	bBAF complex	ARID1B ARID1A	1.15e-04	10	34	2	GO:0140092
GeneOntologyCellularComponent	brahma complex	ARID1B ARID1A	2.31e-04	14	34	2	GO:0035060
GeneOntologyCellularComponent	chromosomal region	CHD4 UPF1 CREBBP STAG2 SS18L1	5.56e-04	421	34	5	GO:0098687
HumanPheno	Cleft palate	KMT2C ARID1B CHD7 CHD4 ARID1A CREBBP YAP1 STAG2 EP300 SMAD3	1.59e-06	643	15	10	HP:0000175
HumanPheno	Abnormal hard palate morphology	KMT2C ARID1B CHD7 CHD4 ARID1A CREBBP YAP1 STAG2 EP300 SMAD3	1.69e-06	647	15	10	HP:0100737
HumanPheno	Thick eyebrow	KMT2C ARID1B ARID1A MBD5 CREBBP EP300	2.77e-06	154	15	6	HP:0000574
HumanPheno	Orofacial cleft	KMT2C ARID1B CHD7 CHD4 ARID1A CREBBP YAP1 STAG2 EP300 SMAD3	3.26e-06	694	15	10	HP:0000202
HumanPheno	Craniofacial cleft	KMT2C ARID1B CHD7 CHD4 ARID1A CREBBP YAP1 STAG2 EP300 SMAD3	3.26e-06	694	15	10	HP:5201015
HumanPheno	Patent ductus arteriosus	ARID1B CHD7 CHD4 ARID1A CREBBP STAG2 EP300 SMAD3	3.75e-06	382	15	8	HP:0001643
HumanPheno	Sandal gap	ARID1B ARID1A MBD5 CREBBP EP300	5.54e-06	96	15	5	HP:0001852
HumanPheno	Plantar crease between first and second toes	CREBBP EP300	8.09e-06	2	15	2	HP:0008107
HumanPheno	Aortic isthmus hypoplasia	CREBBP EP300	8.09e-06	2	15	2	HP:0034227
HumanPheno	High axial triradius	CREBBP EP300	8.09e-06	2	15	2	HP:0001042
HumanPheno	Square face	CHD7 CREBBP EP300	1.13e-05	16	15	3	HP:0000321
HumanPheno	Dislocated radial head	ARID1B CHD7 CREBBP EP300	1.41e-05	54	15	4	HP:0003083
HumanPheno	Abnormality of the radial head	ARID1B CHD7 CREBBP EP300	1.76e-05	57	15	4	HP:0003995
HumanPheno	Hypoplastic facial bones	ARID1B CHD7 MBD5 CREBBP STAG2 EP300 SMAD3	1.88e-05	331	15	7	HP:0002692
HumanPheno	Aplasia/Hypoplasia of facial bones	ARID1B CHD7 MBD5 CREBBP STAG2 EP300 SMAD3	1.91e-05	332	15	7	HP:0034261
HumanPheno	Abnormal posterior cranial fossa morphology	ARID1B CHD7 ARID1A MBD5 CREBBP EP300	2.24e-05	221	15	6	HP:0000932
HumanPheno	Long eyelashes	ARID1B ARID1A MBD5 CREBBP EP300	2.36e-05	129	15	5	HP:0000527
HumanPheno	Laryngeal cartilage malformation	CREBBP EP300	2.42e-05	3	15	2	HP:0008752
HumanPheno	Phobia	CREBBP EP300	2.42e-05	3	15	2	HP:5200232
HumanPheno	Agoraphobia	CREBBP EP300	2.42e-05	3	15	2	HP:0000756
HumanPheno	Humoral immunodeficiency	CREBBP EP300	2.42e-05	3	15	2	HP:0005363
HumanPheno	Prominent nasal septum	CREBBP EP300	2.42e-05	3	15	2	HP:0005322
HumanPheno	Radial deviation of thumb terminal phalanx	CREBBP EP300	2.42e-05	3	15	2	HP:0005895
HumanPheno	Abnormality of the humeroradial joint	ARID1B CHD7 CREBBP EP300	2.46e-05	62	15	4	HP:0100744
HumanPheno	Localized hirsutism	ARID1B CREBBP EP300	2.66e-05	21	15	3	HP:0009889
HumanPheno	Autistic behavior	KMT2C ARID1B CHD7 USF3 ARID1A MBD5 CREBBP STAG2 EP300	2.95e-05	678	15	9	HP:0000729
HumanPheno	Abnormal foramen magnum morphology	CHD4 CREBBP EP300	3.53e-05	23	15	3	HP:0002699
HumanPheno	Abnormality of dental eruption	KMT2C ARID1B CHD7 ARID1A CREBBP EP300	3.59e-05	240	15	6	HP:0006292
HumanPheno	Abnormal skull base morphology	ARID1B CHD7 ARID1A MBD5 CREBBP EP300	3.77e-05	242	15	6	HP:0002693
HumanPheno	Abnormal ureter physiology	TBX18 KMT2C CHD7 CHD4 CREBBP EP300	4.04e-05	245	15	6	HP:0025634
HumanPheno	Congenital malformation of the great arteries	ARID1B CHD7 CHD4 ARID1A CREBBP STAG2 EP300 SMAD3	4.26e-05	529	15	8	HP:0011603
HumanPheno	Low anterior hairline	ARID1B ARID1A CREBBP STAG2 EP300	4.45e-05	147	15	5	HP:0000294
HumanPheno	Trichiasis	CREBBP EP300	4.84e-05	4	15	2	HP:0001128
HumanPheno	Visceral hemangioma	CREBBP EP300	4.84e-05	4	15	2	HP:0410266
HumanPheno	Talon cusp	CREBBP EP300	4.84e-05	4	15	2	HP:0011087
HumanPheno	Widened distal phalanges	CREBBP EP300	4.84e-05	4	15	2	HP:0006200
HumanPheno	Vascular ring	CREBBP EP300	4.84e-05	4	15	2	HP:0010775
HumanPheno	Hepatic hemangioma	CREBBP EP300	4.84e-05	4	15	2	HP:0031207
HumanPheno	Abnormality of the ureter	TBX18 KMT2C ARID1B CHD7 CHD4 CREBBP EP300	4.87e-05	383	15	7	HP:0000069
HumanPheno	Atrial septal defect	ARID1B CHD7 CHD4 ARID1A CREBBP STAG2 EP300 SMAD3	5.03e-05	541	15	8	HP:0001631
HumanPheno	Abnormality of the atrial septum	ARID1B CHD7 CHD4 ARID1A CREBBP STAG2 EP300 SMAD3	5.03e-05	541	15	8	HP:0001630
HumanPheno	Abnormal atrial septum morphology	ARID1B CHD7 CHD4 ARID1A CREBBP STAG2 EP300 SMAD3	5.23e-05	544	15	8	HP:0011994
HumanPheno	Postnatal growth retardation	ARID1B CHD7 ARID1A MBD5 CREBBP EP300	5.41e-05	258	15	6	HP:0008897
HumanPheno	Abnormal palate morphology	KMT2C ARID1B CHD7 CHD4 USF3 ARID1A CREBBP YAP1 STAG2 EP300 SMAD3	6.34e-05	1202	15	11	HP:0000174
HumanPheno	Diagnostic behavioral phenotype	KMT2C ARID1B CHD7 USF3 ARID1A MBD5 CREBBP STAG2 EP300	6.52e-05	747	15	9	HP:0025783
HumanPheno	Short columella	MBD5 CREBBP EP300	7.21e-05	29	15	3	HP:0002000
HumanPheno	Papillary cystadenoma of the epididymis	CREBBP EP300	8.05e-05	5	15	2	HP:0009715
HumanPheno	Supernumerary cusp	CREBBP EP300	8.05e-05	5	15	2	HP:0033777
HumanPheno	Epididymal neoplasm	CREBBP EP300	8.05e-05	5	15	2	HP:0030421
HumanPheno	Elbow dislocation	ARID1B CHD7 CREBBP EP300	8.18e-05	84	15	4	HP:0003042
HumanPheno	Abnormal eyelash morphology	ARID1B ARID1A MBD5 CREBBP STAG2 EP300	9.30e-05	284	15	6	HP:0000499
HumanPheno	Abnormal duodenum morphology	ARID1B CHD7 STAG2 EP300	9.82e-05	88	15	4	HP:0002246
HumanPheno	Abnormal branching pattern of the aortic arch	CHD7 CREBBP EP300	1.07e-04	33	15	3	HP:0011587
HumanPheno	Abnormality of the hairline	ARID1B ARID1A MBD5 CREBBP STAG2 EP300	1.13e-04	294	15	6	HP:0009553
HumanPheno	Large foramen magnum	CREBBP EP300	1.21e-04	6	15	2	HP:0002700
HumanPheno	Abnormality of the dentition	AMBN KMT2C ARID1B CHD7 ARID1A MBD5 CREBBP STAG2 EP300 SMAD3	1.21e-04	1030	15	10	HP:0000164
HumanPheno	Abnormal cardiac atrium morphology	ARID1B CHD7 CHD4 ARID1A CREBBP STAG2 EP300 SMAD3	1.31e-04	617	15	8	HP:0005120
HumanPheno	Upper extremity joint dislocation	ARID1B CHD7 CREBBP EP300	1.38e-04	96	15	4	HP:0030310
HumanPheno	Pneumonia	ARID1B CHD7 ARID1A CREBBP STAG2 EP300	1.54e-04	311	15	6	HP:0002090
HumanPheno	Natal tooth	KMT2C CREBBP EP300	1.64e-04	38	15	3	HP:0000695
HumanPheno	Deviated nasal septum	CREBBP EP300	1.69e-04	7	15	2	HP:0004411
HumanPheno	Abnormal thorax morphology	KMT2C ARID1B CHD7 CHD4 USF3 ARID1A MBD5 CREBBP STAG2 EP300 SMAD3	1.70e-04	1328	15	11	HP:0000765
HumanPheno	Cellular immunodeficiency	USF3 CREBBP EP300	1.77e-04	39	15	3	HP:0005374
HumanPheno	Short finger	ARID1B CHD7 ARID1A MBD5 CREBBP EP300	1.97e-04	325	15	6	HP:0009381
HumanPheno	Congenital abnormal hair pattern	ARID1B ARID1A MBD5 CREBBP STAG2 EP300	2.04e-04	327	15	6	HP:0011361
HumanPheno	Highly arched eyebrow	CHD7 MBD5 CREBBP STAG2 EP300	2.22e-04	206	15	5	HP:0002553
HumanPheno	Cerebellar malformation	ARID1B CHD7 CHD4 ARID1A MBD5 CREBBP EP300	2.27e-04	487	15	7	HP:0002438
HumanPheno	Prominent nose	MBD5 CREBBP STAG2 EP300	2.34e-04	110	15	4	HP:0000448
HumanPheno	Juvenile aseptic necrosis	CREBBP EP300 SMAD3	2.38e-04	43	15	3	HP:0100323
HumanPheno	Self-injurious behavior	KMT2C CHD7 MBD5 CREBBP EP300	2.43e-04	210	15	5	HP:0100716
HumanPheno	Abnormal eyebrow morphology	KMT2C ARID1B CHD7 ARID1A MBD5 CREBBP STAG2 EP300	2.46e-04	674	15	8	HP:0000534
HumanPheno	Thin upper lip vermilion	ARID1B ARID1A MBD5 CREBBP STAG2 EP300	2.49e-04	339	15	6	HP:0000219
HumanPheno	Thin lips	ARID1B ARID1A MBD5 CREBBP STAG2 EP300	2.49e-04	339	15	6	HP:0000213
HumanPheno	Meningioma	USF3 CREBBP EP300	2.55e-04	44	15	3	HP:0002858
HumanPheno	Scoliosis	KMT2C ARID1B CHD7 USF3 ARID1A MBD5 CREBBP STAG2 EP300 SMAD3	2.59e-04	1122	15	10	HP:0002650
HumanPheno	Abnormality of the frontal hairline	ARID1B ARID1A CREBBP STAG2 EP300	2.71e-04	215	15	5	HP:0000599
HumanPheno	Hirsutism	ARID1B ARID1A MBD5 CREBBP EP300	2.77e-04	216	15	5	HP:0001007
HumanPheno	Pilomatrixoma	CREBBP EP300	2.88e-04	9	15	2	HP:0030434
HumanPheno	Cervical cord compression	CREBBP EP300	2.88e-04	9	15	2	HP:0002341
HumanPheno	Prominent fingertip pads	ARID1B CREBBP EP300	2.91e-04	46	15	3	HP:0001212
HumanPheno	Advanced eruption of teeth	KMT2C CREBBP EP300	2.91e-04	46	15	3	HP:0006288
HumanPheno	Abnormal 5th finger morphology	ARID1B CHD7 ARID1A MBD5 CREBBP STAG2 EP300	3.00e-04	509	15	7	HP:0004207
HumanPheno	Ventricular septal defect	ARID1B CHD7 CHD4 ARID1A CREBBP STAG2 EP300	3.04e-04	510	15	7	HP:0001629
HumanPheno	Vesicoureteral reflux	KMT2C CHD7 CHD4 CREBBP EP300	3.09e-04	221	15	5	HP:0000076
HumanPheno	Aggressive behavior	KMT2C ARID1B CHD7 ARID1A MBD5 CREBBP EP300	3.27e-04	516	15	7	HP:0000718
HumanPheno	Abnormal aggressive, impulsive or violent behavior	KMT2C ARID1B CHD7 ARID1A MBD5 CREBBP EP300	3.27e-04	516	15	7	HP:0006919
HumanPheno	Prominent digit pad	ARID1B CREBBP EP300	3.30e-04	48	15	3	HP:0011298
HumanPheno	Unsteady gait	ARID1B CHD7 ARID1A CREBBP STAG2 EP300	3.30e-04	357	15	6	HP:0002317
HumanPheno	Abnormal midface morphology	KMT2C ARID1B CHD7 MBD5 CREBBP STAG2 EP300 SMAD3	3.35e-04	704	15	8	HP:0000309
HumanPheno	Abnormal ventricular septum morphology	ARID1B CHD7 CHD4 ARID1A CREBBP STAG2 EP300	3.48e-04	521	15	7	HP:0010438
HumanPheno	Hypoplastic left heart	CREBBP STAG2 EP300	3.51e-04	49	15	3	HP:0004383
HumanPheno	Abnormality of refraction	KMT2C ARID1B CHD4 USF3 ARID1A MBD5 CREBBP EP300	3.53e-04	709	15	8	HP:0000539
HumanPheno	Frontal hirsutism	CREBBP EP300	3.59e-04	10	15	2	HP:0011335
HumanPheno	Abnormal aortic morphology	CHD7 CHD4 CREBBP STAG2 EP300 SMAD3	3.62e-04	363	15	6	HP:0030963
HumanPheno	Abnormal penis morphology	ARID1B CHD7 CHD4 USF3 ARID1A MBD5 CREBBP EP300	3.63e-04	712	15	8	HP:0000036
HumanPheno	Aplasia/Hypoplasia of fingers	ARID1B CHD7 ARID1A MBD5 CREBBP EP300	3.78e-04	366	15	6	HP:0006265
HumanPheno	Self-mutilation	CHD7 CREBBP EP300	3.95e-04	51	15	3	HP:0000742
HumanPheno	Congenital malformation of the left heart	CREBBP STAG2 EP300	3.95e-04	51	15	3	HP:0045017
HumanPheno	Abnormal subclavian artery morphology	CREBBP EP300	4.38e-04	11	15	2	HP:0031251
HumanPheno	Aplasia/Hypoplasia of the earlobes	CHD7 CREBBP EP300	4.43e-04	53	15	3	HP:0009906
MousePheno	abnormal myocardium layer morphology	FOXO1 TBX18 CHD7 CHD4 TAB1 ARID1A NFAT5 CREBBP EP300	9.51e-08	414	29	9	MP:0005329
MousePheno	abnormal heart layer morphology	FOXO1 TBX18 CHD7 CHD4 TAB1 ARID1A NFAT5 CREBBP EP300	1.12e-07	422	29	9	MP:0010545
MousePheno	abnormal myocardium compact layer morphology	TBX18 CHD4 NFAT5 CREBBP EP300	2.36e-07	67	29	5	MP:0004056
MousePheno	abnormal cardiac muscle tissue morphology	FOXO1 TBX18 CHD7 CHD4 TAB1 ARID1A NFAT5 CREBBP EP300	3.91e-07	489	29	9	MP:0010630
MousePheno	abnormal myocardial trabeculae morphology	FOXO1 CHD4 TAB1 ARID1A NFAT5 EP300	4.21e-07	144	29	6	MP:0002189
MousePheno	lethality during fetal growth through weaning, complete penetrance	TBX18 KMT2C ARID1B CHD4 TAB1 ARID1A MBD5 NFAT5 GCN1 CREBBP EP300 AMOTL1	3.57e-06	1269	29	12	MP:0011111
MousePheno	abnormal muscle morphology	FOXO1 TBX18 CHD7 CHD4 TAB1 ARID1A NFAT5 CREBBP EP300 ARAF MBNL3	6.60e-06	1106	29	11	MP:0002108
MousePheno	perinatal lethality	TBX18 KMT2C ARID1B CHD4 ARID1A MBD5 NFAT5 GCN1 CREBBP EP300 AMOTL1	8.12e-06	1130	29	11	MP:0002081
MousePheno	ventricular septal defect	CHD7 CHD4 TAB1 ARID1A CREBBP EP300	1.32e-05	261	29	6	MP:0010402
MousePheno	abnormal cardiovascular development	FOXO1 TBX18 CHD7 CHD4 TAB1 ARID1A CREBBP YAP1 EP300	2.28e-05	802	29	9	MP:0002925
MousePheno	abnormal interventricular septum morphology	CHD7 CHD4 TAB1 ARID1A CREBBP EP300	6.06e-05	342	29	6	MP:0000281
MousePheno	perinatal lethality, complete penetrance	TBX18 KMT2C ARID1B ARID1A NFAT5 GCN1 EP300 AMOTL1	7.19e-05	712	29	8	MP:0011089
MousePheno	abnormal vascular development	FOXO1 TBX18 CHD7 ARID1A CREBBP YAP1 EP300	9.40e-05	542	29	7	MP:0000259
MousePheno	thin myocardium compact layer	CHD4 CREBBP EP300	1.15e-04	46	29	3	MP:0004057
MousePheno	absent organized vascular network	FOXO1 CREBBP	1.15e-04	8	29	2	MP:0000263
MousePheno	abnormal heart septum morphology	CHD7 CHD4 TAB1 ARID1A CREBBP EP300	1.22e-04	388	29	6	MP:0006113
MousePheno	abnormal fetal cardiomyocyte proliferation	CHD7 CHD4 NFAT5	1.30e-04	48	29	3	MP:0003567
MousePheno	abnormal vasculogenesis	FOXO1 CREBBP EP300	1.85e-04	54	29	3	MP:0001622
MousePheno	abnormal fetal cardiomyocyte physiology	CHD7 CHD4 NFAT5	1.96e-04	55	29	3	MP:0011390
MousePheno	abnormal percent body fat/body weight	FOXO1 CHD7 CLOCK CREBBP	2.10e-04	144	29	4	MP:0005457
MousePheno	postnatal lethality	CHD7 CHD4 TAB1 MBD5 NFAT5 CREBBP EP300 ARAF AMOTL1	2.37e-04	1084	29	9	MP:0002082
MousePheno	incomplete embryo turning	SS18 YAP1 EP300	3.22e-04	65	29	3	MP:0001701
MousePheno	increased grooming behavior	ARID1B MBD5 CREBBP	4.71e-04	74	29	3	MP:0001441
MousePheno	interrupted aortic arch, type b	CHD7 TAB1	4.90e-04	16	29	2	MP:0011659
MousePheno	abnormal blood vessel morphology	FOXO1 TBX18 ARID1B CHD7 TAB1 ARID1A SS18 CREBBP YAP1 EP300	4.97e-04	1472	29	10	MP:0001614
MousePheno	abnormal thymus morphology	CHD7 NFAT5 CLOCK CREBBP EP300 ARAF SMAD3	5.25e-04	717	29	7	MP:0000703
MousePheno	abnormal epicardium morphology	TBX18 EP300	5.54e-04	17	29	2	MP:0003057
MousePheno	embryonic growth arrest	CHD7 ARID1A SS18 CREBBP EP300	6.57e-04	346	29	5	MP:0001730
MousePheno	thin myocardium	CHD7 TAB1 EP300	7.07e-04	85	29	3	MP:0002652
MousePheno	thin ventricle myocardium compact layer	CREBBP EP300	7.71e-04	20	29	2	MP:0010556
MousePheno	lethality throughout fetal growth and development, incomplete penetrance	CHD7 NFAT5 CREBBP EP300	8.45e-04	208	29	4	MP:0011109
MousePheno	decreased circulating luteinizing hormone level	CHD7 CLOCK	8.52e-04	21	29	2	MP:0002773
MousePheno	decreased skeletal muscle fiber number	CHD4 MBNL3	8.52e-04	21	29	2	MP:0009406
MousePheno	abnormal embryonic growth/weight/body size	FOXO1 CHD7 BCL9 ARID1A SS18 GCN1 CREBBP YAP1 EP300	8.84e-04	1295	29	9	MP:0002088
MousePheno	abnormal heart development	FOXO1 CHD7 CHD4 CREBBP EP300	9.11e-04	372	29	5	MP:0000267
MousePheno	absent myocardial trabeculae	ARID1A EP300	9.36e-04	22	29	2	MP:0000293
MousePheno	abnormal heart ventricle morphology	CHD7 CHD4 TAB1 ARID1A NFAT5 CREBBP EP300	9.57e-04	793	29	7	MP:0005294
MousePheno	ventricular hypoplasia	TAB1 CREBBP EP300	1.10e-03	99	29	3	MP:0000279
MousePheno	abnormal cranium morphology	AMBN TBX18 CHD7 MBD5 CLOCK GCN1 CREBBP	1.11e-03	813	29	7	MP:0000438
MousePheno	tubulointerstitial nephritis	NFAT5 SMAD3	1.11e-03	24	29	2	MP:0011405
MousePheno	abnormal pericardium morphology	FOXO1 TBX18 ARID1A EP300	1.13e-03	225	29	4	MP:0000288
MousePheno	open neural tube	ARID1A SS18 CREBBP EP300	1.15e-03	226	29	4	MP:0000929
MousePheno	abnormal heart ventricle wall thickness	CHD4 TAB1 NFAT5 EP300	1.17e-03	227	29	4	MP:0020135
MousePheno	absent heartbeat	FOXO1 ARID1A	1.21e-03	25	29	2	MP:0004086
MousePheno	abnormal fluid regulation	FOXO1 ARID1B CHD7 TAB1 ARID1A NFAT5 EP300	1.22e-03	826	29	7	MP:0001784
MousePheno	abnormal craniofacial bone morphology	AMBN TBX18 CHD7 MBD5 CLOCK GCN1 CREBBP	1.22e-03	827	29	7	MP:0002116
MousePheno	abnormal hypothalamus physiology	ARID1B CHD7	1.31e-03	26	29	2	MP:0005645
MousePheno	abnormal embryo development	FOXO1 CHD7 UPF1 ARID1A SS18 GCN1 CREBBP YAP1 EP300	1.33e-03	1370	29	9	MP:0001672
MousePheno	abnormal vitelline vasculature morphology	FOXO1 CREBBP YAP1 EP300	1.33e-03	235	29	4	MP:0003229
MousePheno	abnormal craniofacial morphology	AMBN FOXO1 TBX18 CHD7 MBD5 CLOCK GCN1 CREBBP EP300	1.34e-03	1372	29	9	MP:0000428
MousePheno	craniofacial phenotype	AMBN FOXO1 TBX18 CHD7 MBD5 CLOCK GCN1 CREBBP EP300	1.34e-03	1372	29	9	MP:0005382
MousePheno	abnormal visceral yolk sac morphology	FOXO1 ARID1A CREBBP YAP1	1.35e-03	236	29	4	MP:0001718
MousePheno	abnormal embryonic tissue morphology	FOXO1 TBX18 CHD7 ARID1A SS18 CREBBP YAP1 EP300	1.51e-03	1116	29	8	MP:0002085
MousePheno	pericardial effusion	FOXO1 ARID1A EP300	1.53e-03	111	29	3	MP:0005312
MousePheno	lethality during fetal growth through weaning, incomplete penetrance	CHD7 CHD4 MBD5 NFAT5 CREBBP EP300 ARAF AMOTL1	1.59e-03	1124	29	8	MP:0011112
MousePheno	decreased pituitary hormone level	CHD7 MBD5 CLOCK	1.61e-03	113	29	3	MP:0003972
MousePheno	abnormal embryo turning	CHD7 SS18 YAP1 EP300	1.69e-03	251	29	4	MP:0001700
MousePheno	decreased circulating free fatty acids level	FOXO1 CHD7 CREBBP	1.74e-03	116	29	3	MP:0002702
MousePheno	abnormal endocrine gland morphology	CHD7 MBD5 NFAT5 CLOCK CREBBP EP300 ARAF SMAD3	1.78e-03	1144	29	8	MP:0013560
MousePheno	lethality throughout fetal growth and development	CHD7 TAB1 NFAT5 CREBBP EP300	1.83e-03	435	29	5	MP:0006208
MousePheno	decreased luteinizing hormone level	CHD7 CLOCK	1.98e-03	32	29	2	MP:0005132
MousePheno	delayed heart development	FOXO1 EP300	1.98e-03	32	29	2	MP:0012082
MousePheno	abnormal axial skeleton morphology	AMBN TBX18 CHD7 TAB1 MBD5 CLOCK GCN1 CREBBP SMAD3	2.06e-03	1458	29	9	MP:0002114
MousePheno	hemorrhage	CHD7 TAB1 ARID1A SS18 CREBBP EP300	2.09e-03	664	29	6	MP:0001914
MousePheno	lethality, complete penetrance	ARID1B CHD7	2.11e-03	33	29	2	MP:0011400
MousePheno	postnatal lethality, incomplete penetrance	CHD7 NFAT5 CREBBP EP300 ARAF AMOTL1	2.17e-03	669	29	6	MP:0011086
Domain	-	CREBBP EP300	3.22e-06	2	34	2	1.10.246.20
Domain	zf-TAZ	CREBBP EP300	3.22e-06	2	34	2	PF02135
Domain	ZF_TAZ	CREBBP EP300	3.22e-06	2	34	2	PS50134
Domain	BAF250_C	ARID1B ARID1A	3.22e-06	2	34	2	IPR033388
Domain	Nuc_rcpt_coact_CREBbp	CREBBP EP300	3.22e-06	2	34	2	IPR014744
Domain	HAT_KAT11	CREBBP EP300	3.22e-06	2	34	2	PF08214
Domain	BAF250_C	ARID1B ARID1A	3.22e-06	2	34	2	PF12031
Domain	KIX	CREBBP EP300	3.22e-06	2	34	2	PS50952
Domain	ZnF_TAZ	CREBBP EP300	3.22e-06	2	34	2	SM00551
Domain	CBP_P300_HAT	CREBBP EP300	3.22e-06	2	34	2	IPR031162
Domain	Histone_AcTrfase_Rtt109/CBP	CREBBP EP300	3.22e-06	2	34	2	IPR013178
Domain	DUF902	CREBBP EP300	3.22e-06	2	34	2	PF06001
Domain	BAF250/Osa	ARID1B ARID1A	3.22e-06	2	34	2	IPR021906
Domain	-	CREBBP EP300	3.22e-06	2	34	2	1.20.1020.10
Domain	RING_CBP-p300	CREBBP EP300	3.22e-06	2	34	2	IPR010303
Domain	KAT11	CREBBP EP300	3.22e-06	2	34	2	SM01250
Domain	-	CREBBP EP300	3.22e-06	2	34	2	1.10.1630.10
Domain	Znf_TAZ	CREBBP EP300	3.22e-06	2	34	2	IPR000197
Domain	KIX_dom	CREBBP EP300	3.22e-06	2	34	2	IPR003101
Domain	Creb_binding	CREBBP EP300	3.22e-06	2	34	2	PF09030
Domain	KIX	CREBBP EP300	3.22e-06	2	34	2	PF02172
Domain	CBP_P300_HAT	CREBBP EP300	3.22e-06	2	34	2	PS51727
Domain	SSXT	SS18 SS18L1	9.64e-06	3	34	2	PF05030
Domain	SS18_fam	SS18 SS18L1	9.64e-06	3	34	2	IPR007726
Domain	Nuc_rcpt_coact	CREBBP EP300	4.80e-05	6	34	2	IPR009110
Domain	-	ARID1B ARID1A	3.33e-04	15	34	2	1.10.150.60
Domain	ARID	ARID1B ARID1A	3.33e-04	15	34	2	PF01388
Domain	BRIGHT	ARID1B ARID1A	3.33e-04	15	34	2	SM00501
Domain	ARID_dom	ARID1B ARID1A	3.33e-04	15	34	2	IPR001606
Domain	ARID	ARID1B ARID1A	3.33e-04	15	34	2	PS51011
Domain	ZF_ZZ_2	CREBBP EP300	4.83e-04	18	34	2	PS50135
Domain	ZF_ZZ_1	CREBBP EP300	4.83e-04	18	34	2	PS01357
Domain	ZZ	CREBBP EP300	4.83e-04	18	34	2	PF00569
Domain	Znf_ZZ	CREBBP EP300	5.39e-04	19	34	2	IPR000433
Domain	ZnF_ZZ	CREBBP EP300	5.39e-04	19	34	2	SM00291
Domain	Chromo_domain	CHD7 CHD4	8.66e-04	24	34	2	IPR023780
Domain	Chromo	CHD7 CHD4	1.02e-03	26	34	2	PF00385
Domain	Bromodomain_CS	CREBBP EP300	1.02e-03	26	34	2	IPR018359
Domain	CHROMO_2	CHD7 CHD4	1.18e-03	28	34	2	PS50013
Domain	CHROMO_1	CHD7 CHD4	1.18e-03	28	34	2	PS00598
Domain	ARM-like	ARID1B ARID1A GCN1 STAG2	1.41e-03	270	34	4	IPR011989
Domain	SNF2_N	CHD7 CHD4	1.54e-03	32	34	2	PF00176
Domain	SNF2_N	CHD7 CHD4	1.54e-03	32	34	2	IPR000330
Domain	Chromodomain-like	CHD7 CHD4	1.54e-03	32	34	2	IPR016197
Domain	CHROMO	CHD7 CHD4	1.64e-03	33	34	2	SM00298
Domain	Chromo/shadow_dom	CHD7 CHD4	1.64e-03	33	34	2	IPR000953
Domain	DNA/RNA_helicase_DEAH_CS	CHD7 CHD4	1.84e-03	35	34	2	IPR002464
Domain	BROMODOMAIN_1	CREBBP EP300	2.06e-03	37	34	2	PS00633
Domain	DEAH_ATP_HELICASE	CHD7 CHD4	2.17e-03	38	34	2	PS00690
Domain	Bromodomain	CREBBP EP300	2.17e-03	38	34	2	PF00439
Domain	Znf_FYVE_PHD	KMT2C CHD4 ZFYVE9	2.39e-03	147	34	3	IPR011011
Domain	BROMODOMAIN_2	CREBBP EP300	2.52e-03	41	34	2	PS50014
Domain	BROMO	CREBBP EP300	2.65e-03	42	34	2	SM00297
Domain	Bromodomain	CREBBP EP300	2.65e-03	42	34	2	IPR001487
Domain	-	CREBBP EP300	2.65e-03	42	34	2	1.20.920.10
Domain	p53-like_TF_DNA-bd	TBX18 NFAT5	4.18e-03	53	34	2	IPR008967
Domain	C1	KMT2C ARAF	6.23e-03	65	34	2	SM00109
Domain	HMG_box_dom	KMT2C CHD4	6.23e-03	65	34	2	IPR009071
Domain	PE/DAG-bd	KMT2C ARAF	6.41e-03	66	34	2	IPR002219
Pathway	BIOCARTA_TGFB_PATHWAY	TAB1 ZFYVE9 CREBBP EP300 SMAD3	3.50e-10	19	30	5	M18933
Pathway	REACTOME_NOTCH4_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION	MAML2 CREBBP EP300 SMAD3	7.88e-08	20	30	4	M27881
Pathway	WP_KLEEFSTRA_SYNDROME	KMT2C ARID1B ARID1A MBD5	3.81e-07	29	30	4	M48076
Pathway	REACTOME_EPIGENETIC_REGULATION_OF_GENE_EXPRESSION	KMT2C ARID1B CHD4 ARID1A SS18 EP300 SS18L1	8.11e-07	254	30	7	M27131
Pathway	REACTOME_REGULATION_OF_FOXO_TRANSCRIPTIONAL_ACTIVITY_BY_ACETYLATION	FOXO1 CREBBP EP300	1.03e-06	10	30	3	M27945
Pathway	REACTOME_CHROMATIN_MODIFYING_ENZYMES	KMT2C ARID1B CHD4 ARID1A CLOCK CREBBP EP300	1.28e-06	272	30	7	M29619
Pathway	REACTOME_TRANSCRIPTIONAL_REGULATION_BY_RUNX3	MAML2 CREBBP YAP1 EP300 SMAD3	1.64e-06	96	30	5	M27784
Pathway	REACTOME_REGULATION_OF_ENDOGENOUS_RETROELEMENTS_BY_PIWI_INTERACTING_RNAS_PIRNAS	ARID1B CHD4 ARID1A SS18 SS18L1	1.73e-06	97	30	5	M48262
Pathway	REACTOME_REGULATION_OF_MITF_M_DEPENDENT_GENES_INVOLVED_IN_PIGMENTATION	ARID1B ARID1A SS18 SS18L1	1.76e-06	42	30	4	M48237
Pathway	REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT	FOXO1 MAML2 CREBBP EP300	1.76e-06	42	30	4	M17541
Pathway	REACTOME_DEVELOPMENTAL_BIOLOGY	MED14 FOXO1 KMT2C ARID1B CHD4 MAML2 ARID1A SS18 CREBBP YAP1 EP300 SS18L1 SMAD3	2.65e-06	1432	30	13	M509
Pathway	REACTOME_RUNX3_REGULATES_NOTCH_SIGNALING	MAML2 CREBBP EP300	3.12e-06	14	30	3	M27808
Pathway	WP_RUBINSTEINTAYBI_SYNDROME_1	FOXO1 CLOCK CREBBP	3.89e-06	15	30	3	M48323
Pathway	WP_TGFBETA_SIGNALING_PATHWAY	ZFYVE9 CREBBP EP300 SMAD3	4.54e-06	53	30	4	MM15880
Pathway	REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_LATE_STAGE_BRANCHING_MORPHOGENESIS_PANCREATIC_BUD_PRECURSOR_CELLS	MAML2 CREBBP EP300	4.78e-06	16	30	3	M27121
Pathway	REACTOME_FOXO_MEDIATED_TRANSCRIPTION_OF_CELL_DEATH_GENES	FOXO1 CREBBP EP300	4.78e-06	16	30	3	M27940
Pathway	PID_TGFBR_PATHWAY	TAB1 ZFYVE9 YAP1 SMAD3	4.89e-06	54	30	4	M286
Pathway	WP_TGFBETA_RECEPTOR_SIGNALING	ZFYVE9 CREBBP EP300 SMAD3	5.27e-06	55	30	4	M39351
Pathway	BIOCARTA_TGFB_PATHWAY	CREBBP EP300 SMAD3	5.80e-06	17	30	3	MM1509
Pathway	REACTOME_ZYGOTIC_GENOME_ACTIVATION_ZGA	CREBBP YAP1 EP300	5.80e-06	17	30	3	M48025
Pathway	WP_TGFBETA_RECEPTOR_SIGNALING_IN_SKELETAL_DYSPLASIAS	ZFYVE9 CREBBP EP300 SMAD3	6.99e-06	59	30	4	M39886
Pathway	REACTOME_GASTRULATION	MAML2 CREBBP YAP1 EP300 SMAD3	7.04e-06	129	30	5	M46433
Pathway	REACTOME_TRANSCRIPTIONAL_REGULATION_BY_RUNX1	KMT2C ARID1B ARID1A CREBBP YAP1 EP300	8.97e-06	237	30	6	M27786
Pathway	REACTOME_MITF_M_REGULATED_MELANOCYTE_DEVELOPMENT	ARID1B ARID1A SS18 CREBBP SS18L1	9.44e-06	137	30	5	M48232
Pathway	WP_PATHWAYS_AFFECTED_IN_ADENOID_CYSTIC_CARCINOMA	KMT2C ARID1A CREBBP EP300	1.03e-05	65	30	4	M39682
Pathway	REACTOME_FOXO_MEDIATED_TRANSCRIPTION	FOXO1 CREBBP EP300 SMAD3	1.10e-05	66	30	4	M27938
Pathway	REACTOME_REGULATION_OF_ENDOGENOUS_RETROELEMENTS	ARID1B CHD4 ARID1A SS18 SS18L1	1.12e-05	142	30	5	M48257
Pathway	BIOCARTA_VDR_PATHWAY	ARID1A CREBBP EP300	1.30e-05	22	30	3	MM1370
Pathway	BIOCARTA_NTHI_PATHWAY	CREBBP EP300 SMAD3	1.30e-05	22	30	3	MM1443
Pathway	REACTOME_FOXO_MEDIATED_TRANSCRIPTION	FOXO1 EP300 SMAD3	1.30e-05	22	30	3	MM15656
Pathway	BIOCARTA_NTHI_PATHWAY	CREBBP EP300 SMAD3	1.50e-05	23	30	3	M2821
Pathway	WP_HEPATITIS_B_INFECTION	TAB1 CREBBP EP300 ARAF SMAD3	1.51e-05	151	30	5	M39801
Pathway	BIOCARTA_VDR_PATHWAY	ARID1A CREBBP EP300	1.71e-05	24	30	3	M13404
Pathway	REACTOME_TRANSCRIPTIONAL_REGULATION_BY_RUNX3	MAML2 YAP1 EP300 SMAD3	1.92e-05	76	30	4	MM15520
Pathway	REACTOME_NOTCH3_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION	MAML2 CREBBP EP300	1.94e-05	25	30	3	M27880
Pathway	PID_HDAC_CLASSIII_PATHWAY	FOXO1 CREBBP EP300	2.19e-05	26	30	3	M32
Pathway	PID_SMAD2_3NUCLEAR_PATHWAY	FOXO1 CREBBP EP300 SMAD3	2.60e-05	82	30	4	M2
Pathway	REACTOME_SIGNALING_BY_NOTCH4	MAML2 CREBBP EP300 SMAD3	2.60e-05	82	30	4	M594
Pathway	KEGG_TGF_BETA_SIGNALING_PATHWAY	ZFYVE9 CREBBP EP300 SMAD3	3.13e-05	86	30	4	M2642
Pathway	KEGG_PROSTATE_CANCER	FOXO1 CREBBP EP300 ARAF	3.59e-05	89	30	4	M13191
Pathway	WP_ANDROGEN_RECEPTOR_SIGNALING	FOXO1 CREBBP EP300 SMAD3	3.92e-05	91	30	4	M39700
Pathway	REACTOME_DISEASES_OF_SIGNAL_TRANSDUCTION_BY_GROWTH_FACTOR_RECEPTORS_AND_SECOND_MESSENGERS	FOXO1 MAML2 ZFYVE9 CREBBP EP300 ARAF SMAD3	4.22e-05	464	30	7	M27547
Pathway	BIOCARTA_PELP1_PATHWAY	CREBBP EP300	4.36e-05	5	30	2	MM1575
Pathway	REACTOME_NFE2L2_REGULATING_INFLAMMATION_ASSOCIATED_GENES	CREBBP EP300	4.36e-05	5	30	2	M48020
Pathway	REACTOME_NFE2L2_REGULATING_ER_STRESS_ASSOCIATED_GENES	CREBBP EP300	4.36e-05	5	30	2	M48023
Pathway	REACTOME_LRR_FLII_INTERACTING_PROTEIN_1_LRRFIP1_ACTIVATES_TYPE_I_IFN_PRODUCTION	CREBBP EP300	4.36e-05	5	30	2	M27228
Pathway	REACTOME_MITF_M_DEPENDENT_GENE_EXPRESSION	ARID1B ARID1A SS18 SS18L1	4.64e-05	95	30	4	M48268
Pathway	REACTOME_RUNX1_INTERACTS_WITH_CO_FACTORS_WHOSE_PRECISE_EFFECT_ON_RUNX1_TARGETS_IS_NOT_KNOWN	ARID1B ARID1A EP300	6.44e-05	37	30	3	M27797
Pathway	BIOCARTA_PELP1_PATHWAY	CREBBP EP300	6.53e-05	6	30	2	M22062
Pathway	REACTOME_REGULATION_OF_FOXO_TRANSCRIPTIONAL_ACTIVITY_BY_ACETYLATION	FOXO1 EP300	6.53e-05	6	30	2	MM15660
Pathway	REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION	MED14 FOXO1 KMT2C ARID1B CHD4 MAML2 ARID1A CREBBP YAP1 EP300 SMAD3	7.50e-05	1387	30	11	M734
Pathway	REACTOME_ADIPOGENESIS	MED14 CHD4 CREBBP EP300	8.23e-05	110	30	4	M48259
Pathway	BIOCARTA_PPARG_PATHWAY	CREBBP EP300	9.13e-05	7	30	2	MM1573
Pathway	REACTOME_LOSS_OF_FUNCTION_OF_SMAD2_3_IN_CANCER	ZFYVE9 SMAD3	9.13e-05	7	30	2	M29623
Pathway	REACTOME_FOXO_MEDIATED_TRANSCRIPTION_OF_CELL_CYCLE_GENES	FOXO1 SMAD3	9.13e-05	7	30	2	MM15661
Pathway	REACTOME_REGULATION_OF_LIPID_METABOLISM_BY_PPARALPHA	MED14 CLOCK CREBBP EP300	1.08e-04	118	30	4	M27316
Pathway	BIOCARTA_PPARG_PATHWAY	CREBBP EP300	1.22e-04	8	30	2	M22058
Pathway	REACTOME_NFE2L2_REGULATING_MDR_ASSOCIATED_ENZYMES	CREBBP EP300	1.22e-04	8	30	2	M48022
Pathway	REACTOME_REGULATION_OF_NFE2L2_GENE_EXPRESSION	CREBBP EP300	1.22e-04	8	30	2	M48024
Pathway	REACTOME_SIGNALING_BY_TGF_BETA_RECEPTOR_COMPLEX_IN_CANCER	ZFYVE9 SMAD3	1.22e-04	8	30	2	M27246
Pathway	REACTOME_NFE2L2_REGULATES_PENTOSE_PHOSPHATE_PATHWAY_GENES	CREBBP EP300	1.22e-04	8	30	2	M46443
Pathway	KEGG_NOTCH_SIGNALING_PATHWAY	MAML2 CREBBP EP300	1.32e-04	47	30	3	M7946
Pathway	KEGG_CELL_CYCLE	CREBBP STAG2 EP300 SMAD3	1.35e-04	125	30	4	M7963
Pathway	PID_HES_HEY_PATHWAY	MAML2 CREBBP EP300	1.41e-04	48	30	3	M288
Pathway	REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION	MAML2 CREBBP EP300	1.41e-04	48	30	3	M611
Pathway	REACTOME_HEME_SIGNALING	CLOCK CREBBP EP300	1.50e-04	49	30	3	M41832
Pathway	REACTOME_SIGNALING_BY_NOTCH3	MAML2 CREBBP EP300	1.50e-04	49	30	3	M618
Pathway	PID_FOXO_PATHWAY	FOXO1 CREBBP EP300	1.50e-04	49	30	3	M136
Pathway	KEGG_MEDICUS_REFERENCE_TLR3_IRF3_SIGNALING_PATHWAY	CREBBP EP300	1.56e-04	9	30	2	M47451
Pathway	PID_AR_TF_PATHWAY	FOXO1 CREBBP EP300	1.90e-04	53	30	3	M151
Pathway	REACTOME_RUNX3_REGULATES_NOTCH_SIGNALING	MAML2 EP300	1.95e-04	10	30	2	MM15535
Pathway	BIOCARTA_CARM1_PATHWAY	CREBBP EP300	2.38e-04	11	30	2	MM1521
Pathway	REACTOME_NFE2L2_REGULATING_TUMORIGENIC_GENES	CREBBP EP300	2.38e-04	11	30	2	M48021
Pathway	REACTOME_REGULATION_OF_GENE_EXPRESSION_BY_HYPOXIA_INDUCIBLE_FACTOR	CREBBP EP300	2.38e-04	11	30	2	M26924
Pathway	REACTOME_SIGNALING_BY_NOTCH1_PEST_DOMAIN_MUTANTS_IN_CANCER	MAML2 CREBBP EP300	2.48e-04	58	30	3	M29616
Pathway	KEGG_WNT_SIGNALING_PATHWAY	NFAT5 CREBBP EP300 SMAD3	2.79e-04	151	30	4	M19428
Pathway	BIOCARTA_CARM1_PATHWAY	CREBBP EP300	2.85e-04	12	30	2	M7968
Pathway	REACTOME_ACTIVATION_OF_THE_TFAP2_AP_2_FAMILY_OF_TRANSCRIPTION_FACTORS	CREBBP EP300	2.85e-04	12	30	2	M27765
Pathway	REACTOME_NOTCH2_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION	MAML2 EP300	2.85e-04	12	30	2	M27159
Pathway	PID_HIF1_TFPATHWAY	CREBBP EP300 SMAD3	3.64e-04	66	30	3	M255
Pathway	PID_HDAC_CLASSI_PATHWAY	CHD4 CREBBP EP300	3.64e-04	66	30	3	M101
Pathway	REACTOME_FORMATION_OF_AXIAL_MESODERM	YAP1 SMAD3	3.92e-04	14	30	2	M46441
Pathway	WP_UROTENSINIIMEDIATED_SIGNALING	CREBBP EP300 SMAD3	4.14e-04	69	30	3	M48052
Pathway	REACTOME_FORMATION_OF_PARAXIAL_MESODERM	MAML2 CREBBP EP300	4.14e-04	69	30	3	M46439
Pathway	KEGG_RENAL_CELL_CARCINOMA	CREBBP EP300 ARAF	4.32e-04	70	30	3	M13266
Pathway	KEGG_LONG_TERM_POTENTIATION	CREBBP EP300 ARAF	4.32e-04	70	30	3	M3115
Pathway	REACTOME_CIRCADIAN_CLOCK	CLOCK CREBBP EP300	4.32e-04	70	30	3	M938
Pathway	BIOCARTA_RELA_PATHWAY	CREBBP EP300	4.52e-04	15	30	2	MM1339
Pathway	BIOCARTA_RELA_PATHWAY	CREBBP EP300	4.52e-04	15	30	2	M10183
Pathway	BIOCARTA_PITX2_PATHWAY	CREBBP EP300	4.52e-04	15	30	2	MM1439
Pathway	REACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY	CREBBP EP300	4.52e-04	15	30	2	M953
Pathway	KEGG_ADHERENS_JUNCTION	CREBBP EP300 SMAD3	4.89e-04	73	30	3	M638
Pathway	REACTOME_SIGNALING_BY_NOTCH1	MAML2 CREBBP EP300	5.09e-04	74	30	3	M616
Pathway	BIOCARTA_IL7_PATHWAY	CREBBP EP300	5.16e-04	16	30	2	M1296
Pathway	BIOCARTA_IL7_PATHWAY	CREBBP EP300	5.16e-04	16	30	2	MM1420
Pathway	BIOCARTA_PITX2_PATHWAY	CREBBP EP300	5.16e-04	16	30	2	M8516
Pathway	REACTOME_SARS_COV_1_TARGETS_HOST_INTRACELLULAR_SIGNALLING_AND_REGULATORY_PATHWAYS	EP300 SMAD3	5.16e-04	16	30	2	M46428
Pathway	KEGG_PATHWAYS_IN_CANCER	FOXO1 CREBBP EP300 ARAF SMAD3	5.60e-04	325	30	5	M12868
Pathway	REACTOME_FOXO_MEDIATED_TRANSCRIPTION_OF_CELL_CYCLE_GENES	FOXO1 SMAD3	5.84e-04	17	30	2	M27946
Pathway	PID_MYC_ACTIV_PATHWAY	CREBBP EP300 SMAD3	6.17e-04	79	30	3	M66
Pubmed	The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.	ARID1B CHD7 CHD4 ARID1A SS18 CREBBP EP300 SS18L1	2.37e-12	157	34	8	30186101
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	MED14 KMT2C ARID1B TAB1 UPF1 ARID1A GCN1 CREBBP YAP1 EP300 AMOTL1	2.83e-12	549	34	11	38280479
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	MED14 ARID1B CHD7 CHD4 BCL9 ARID1A CREBBP YAP1	1.71e-10	268	34	8	33640491
Pubmed	Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.	ARID1B CHD7 BCL9 ARID1A STAG2 EP300	1.96e-10	83	34	6	28794006
Pubmed	Identification and Functional Characterization of a Novel Androgen Receptor Coregulator, EAP1.	ARID1B CHD4 ARID1A CREBBP EP300	4.22e-10	40	34	5	34585037
Pubmed	Dendrite development regulated by CREST, a calcium-regulated transcriptional activator.	CREBBP EP300 SS18L1	8.54e-10	3	34	3	14716005
Pubmed	Kinetic analysis of npBAF to nBAF switching reveals exchange of SS18 with CREST and integration with neural developmental pathways.	ARID1B ARID1A SS18 SS18L1	1.03e-09	15	34	4	23785148
Pubmed	Interaction network of human early embryonic transcription factors.	KMT2C ARID1B CHD7 BCL9 ARID1A CREBBP EP300 SS18L1	1.44e-09	351	34	8	38297188
Pubmed	Chromatin accessibility complex subunit 1 enhances tumor growth by regulating the oncogenic transcription of YAP in breast and cervical cancer.	CHD4 UPF1 ARID1A YAP1 AMOTL1	2.65e-09	57	34	5	38223760
Pubmed	CBP/p300 is a cell type-specific modulator of CLOCK/BMAL1-mediated transcription.	CLOCK CREBBP EP300	3.41e-09	4	34	3	19922678
Pubmed	MLL3/MLL4 are required for CBP/p300 binding on enhancers and super-enhancer formation in brown adipogenesis.	KMT2C CREBBP EP300	3.41e-09	4	34	3	28398509
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	MED14 KMT2C ARID1B CHD7 CHD4 UPF1 BCL9 ARID1A CREBBP STAG2 EP300	4.55e-09	1103	34	11	34189442
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	ARID1B CHD7 BCL9 ARID1A SS18 CREBBP STAG2 EP300 SS18L1	7.75e-09	638	34	9	31182584
Pubmed	Smad3 induces chondrogenesis through the activation of SOX9 via CREB-binding protein/p300 recruitment.	CREBBP EP300 SMAD3	8.52e-09	5	34	3	15623506
Pubmed	Regulation of Smad signaling through a differential recruitment of coactivators and corepressors by ZEB proteins.	CREBBP EP300 SMAD3	8.52e-09	5	34	3	12743039
Pubmed	TGF-beta-stimulated cooperation of smad proteins with the coactivators CBP/p300.	CREBBP EP300 SMAD3	8.52e-09	5	34	3	9679056
Pubmed	E1A inhibits transforming growth factor-beta signaling through binding to Smad proteins.	CREBBP EP300 SMAD3	8.52e-09	5	34	3	10497242
Pubmed	DAF-16 recruits the CREB-binding protein coactivator complex to the insulin-like growth factor binding protein 1 promoter in HepG2 cells.	FOXO1 CREBBP EP300	1.70e-08	6	34	3	10973497
Pubmed	Coactivation of the CLOCK-BMAL1 complex by CBP mediates resetting of the circadian clock.	CLOCK CREBBP EP300	1.70e-08	6	34	3	20930143
Pubmed	CBP-mediated FOXO-1 acetylation inhibits pancreatic tumor growth by targeting SirT.	FOXO1 CREBBP EP300	1.70e-08	6	34	3	24419059
Pubmed	Transforming activity of MECT1-MAML2 fusion oncoprotein is mediated by constitutive CREB activation.	MAML2 CREBBP EP300	1.70e-08	6	34	3	15961999
Pubmed	RNF138 inhibits late inflammatory gene transcription through degradation of SMARCC1 of the SWI/SNF complex.	ARID1B CHD4 UPF1 ARID1A	1.78e-08	29	34	4	36800290
Pubmed	A human MAP kinase interactome.	KMT2C USF3 MBD5 SS18 GCN1 CREBBP EP300 ARAF	1.81e-08	486	34	8	20936779
Pubmed	Reversible disruption of mSWI/SNF (BAF) complexes by the SS18-SSX oncogenic fusion in synovial sarcoma.	ARID1B ARID1A SS18	2.98e-08	7	34	3	23540691
Pubmed	A WW domain protein TAZ is a critical coactivator for TBX5, a transcription factor implicated in Holt-Oram syndrome.	CREBBP YAP1 EP300	2.98e-08	7	34	3	16332960
Pubmed	Pokemon (FBI-1) interacts with Smad4 to repress TGF-β-induced transcriptional responses.	CREBBP EP300 SMAD3	2.98e-08	7	34	3	25514493
Pubmed	Activation of Smad transcriptional activity by protein inhibitor of activated STAT3 (PIAS3).	CREBBP EP300 SMAD3	4.76e-08	8	34	3	14691252
Pubmed	Human transcription factor protein interaction networks.	KMT2C ARID1B CHD7 UPF1 BCL9 ARID1A SS18 CREBBP YAP1 EP300 SS18L1	6.48e-08	1429	34	11	35140242
Pubmed	Hematopoiesis controlled by distinct TIF1gamma and Smad4 branches of the TGFbeta pathway.	ARID1B CREBBP SMAD3	1.02e-07	10	34	3	16751102
Pubmed	Genome-wide impact of the BRG1 SWI/SNF chromatin remodeler on the transforming growth factor beta transcriptional program.	ARID1A CREBBP SMAD3	1.40e-07	11	34	3	18003620
Pubmed	EVI1 oncoprotein interacts with a large and complex network of proteins and integrates signals through protein phosphorylation.	ARID1B CHD4 UPF1 STAG2 SMAD3	1.59e-07	128	34	5	23858473
Pubmed	Intraflagellar Transport Complex B Proteins Regulate the Hippo Effector Yap1 during Cardiogenesis.	TBX18 YAP1 AMOTL1	1.87e-07	12	34	3	32698004
Pubmed	SYT associates with human SNF/SWI complexes and the C-terminal region of its fusion partner SSX1 targets histones.	ARID1B ARID1A SS18	1.87e-07	12	34	3	11734557
Pubmed	Histone acetyltransferase-dependent chromatin remodeling and the vascular clock.	CLOCK CREBBP EP300	1.87e-07	12	34	3	14645221
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	ARID1B TAB1 ARID1A YAP1 ARAF AMOTL1 RAB11FIP2	2.17e-07	446	34	7	24255178
Pubmed	New nomenclature for chromatin-modifying enzymes.	KMT2C CLOCK CREBBP EP300	2.90e-07	57	34	4	18022353
Pubmed	Rescue of deficits by Brwd1 copy number restoration in the Ts65Dn mouse model of Down syndrome.	ARID1B SS18 SS18L1	3.08e-07	14	34	3	36289231
Pubmed	A lentiviral functional proteomics approach identifies chromatin remodeling complexes important for the induction of pluripotency.	KMT2C ARID1B ARID1A SS18	3.82e-07	61	34	4	20305087
Pubmed	Cohesin regulates tissue-specific expression by stabilizing highly occupied cis-regulatory modules.	CREBBP STAG2 EP300	4.74e-07	16	34	3	22780989
Pubmed	Loss of BAF (mSWI/SNF) Complexes Causes Global Transcriptional and Chromatin State Changes in Forebrain Development.	ARID1B ARID1A SS18 SS18L1	4.94e-07	65	34	4	26655900
Pubmed	Identification of the hypoxia-inducible factor 2α nuclear interactome in melanoma cells reveals master proteins involved in melanoma development.	MED14 ARID1B CREBBP EP300	5.25e-07	66	34	4	23275444
Pubmed	TRIM28 interacts with EZH2 and SWI/SNF to activate genes that promote mammosphere formation.	CHD4 ARID1A EP300	6.90e-07	18	34	3	28068325
Pubmed	The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.	CHD4 ARID1A SS18 CREBBP EP300 AMOTL1	7.77e-07	332	34	6	37433992
Pubmed	Acetylation-regulated interaction between p53 and SET reveals a widespread regulatory mode.	FOXO1 CREBBP EP300	8.18e-07	19	34	3	27626385
Pubmed	Acetylation of poly(ADP-ribose) polymerase-1 by p300/CREB-binding protein regulates coactivation of NF-kappaB-dependent transcription.	MED14 CREBBP EP300	8.18e-07	19	34	3	16204234
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	AMBN ARID1B CHD4 ARID1A SS18 CREBBP EP300 ARAF SS18L1	8.89e-07	1116	34	9	31753913
Pubmed	Loss of p300 accelerates MDS-associated leukemogenesis.	CREBBP EP300	9.28e-07	2	34	2	27881875
Pubmed	Molecular characterization of the histone acetyltransferase CREBBP/EP300 genes in myeloid neoplasia.	CREBBP EP300	9.28e-07	2	34	2	34845315
Pubmed	Dual ARID1A/ARID1B loss leads to rapid carcinogenesis and disruptive redistribution of BAF complexes.	ARID1B ARID1A	9.28e-07	2	34	2	34386776
Pubmed	Recurrent YAP1 and MAML2 Gene Rearrangements in Retiform and Composite Hemangioendothelioma.	MAML2 YAP1	9.28e-07	2	34	2	32991341
Pubmed	p300 plays a critical role in maintaining cardiac mitochondrial function and cell survival in postnatal hearts.	CREBBP EP300	9.28e-07	2	34	2	19729597
Pubmed	Integrated genomic analyses identify ARID1A and ARID1B alterations in the childhood cancer neuroblastoma.	ARID1B ARID1A	9.28e-07	2	34	2	23202128
Pubmed	Endogenous CCAAT/enhancer binding protein beta and p300 are both regulated by growth hormone to mediate transcriptional activation.	CREBBP EP300	9.28e-07	2	34	2	15860545
Pubmed	Further delineation of an entity caused by CREBBP and EP300 mutations but not resembling Rubinstein-Taybi syndrome.	CREBBP EP300	9.28e-07	2	34	2	29460469
Pubmed	Expression of p300 and CBP is associated with poor prognosis in small cell lung cancer.	CREBBP EP300	9.28e-07	2	34	2	24551300
Pubmed	ARID1 proteins: from transcriptional and post-translational regulation to carcinogenesis and potential therapeutics.	ARID1B ARID1A	9.28e-07	2	34	2	33890484
Pubmed	Genome-wide CRISPR screens reveal synthetic lethal interaction between CREBBP and EP300 in diffuse large B-cell lymphoma.	CREBBP EP300	9.28e-07	2	34	2	33911074
Pubmed	The adenovirus 12 E1A proteins can bind directly to proteins of the p300 transcription co-activator family, including the CREB-binding protein CBP and p300.	CREBBP EP300	9.28e-07	2	34	2	9018065
Pubmed	Coactivators p300 and CBP maintain the identity of mouse embryonic stem cells by mediating long-range chromatin structure.	CREBBP EP300	9.28e-07	2	34	2	24648406
Pubmed	CBP and P300 regulate distinct gene networks required for human primary myoblast differentiation and muscle integrity.	CREBBP EP300	9.28e-07	2	34	2	30135524
Pubmed	Dynamic changes in chromatin acetylation and the expression of histone acetyltransferases and histone deacetylases regulate the SM22alpha transcription in response to Smad3-mediated TGFbeta1 signaling.	EP300 SMAD3	9.28e-07	2	34	2	16876108
Pubmed	CREB-binding protein/P300 bromodomain inhibition reduces neutrophil accumulation and activates antitumor immunity in triple-negative breast cancer.	CREBBP EP300	9.28e-07	2	34	2	39287984
Pubmed	Distribution of co-activators CBP and p300 during mouse oocyte and embryo development.	CREBBP EP300	9.28e-07	2	34	2	16596650
Pubmed	The p300 and CBP Transcriptional Coactivators Are Required for β-Cell and α-Cell Proliferation.	CREBBP EP300	9.28e-07	2	34	2	29217654
Pubmed	ARID1B is a specific vulnerability in ARID1A-mutant cancers.	ARID1B ARID1A	9.28e-07	2	34	2	24562383
Pubmed	Exon deletions of the EP300 and CREBBP genes in two children with Rubinstein-Taybi syndrome detected by aCGH.	CREBBP EP300	9.28e-07	2	34	2	20717166
Pubmed	Differences in the interactions of oncogenic adenovirus 12 early region 1A and nononcogenic adenovirus 2 early region 1A with the cellular coactivators p300 and CBP.	CREBBP EP300	9.28e-07	2	34	2	10049825
Pubmed	AMOTL1 enhances YAP1 stability and promotes YAP1-driven gastric oncogenesis.	YAP1 AMOTL1	9.28e-07	2	34	2	32313226
Pubmed	CBP/p300 acetyltransferase activity in hematologic malignancies.	CREBBP EP300	9.28e-07	2	34	2	27380996
Pubmed	CREBBP and p300 lysine acetyl transferases in the DNA damage response.	CREBBP EP300	9.28e-07	2	34	2	29170789
Pubmed	The epigenetic regulators CBP and p300 facilitate leukemogenesis and represent therapeutic targets in acute myeloid leukemia.	CREBBP EP300	9.28e-07	2	34	2	25893291
Pubmed	Human T-lymphotropic virus type 1 p30(II) regulates gene transcription by binding CREB binding protein/p300.	CREBBP EP300	9.28e-07	2	34	2	11559821
Pubmed	Crebbp haploinsufficiency in mice alters the bone marrow microenvironment, leading to loss of stem cells and excessive myelopoiesis.	CREBBP EP300	9.28e-07	2	34	2	21555743
Pubmed	CBP/p300 induction is required for retinoic acid sensitivity in human mammary cells.	CREBBP EP300	9.28e-07	2	34	2	12646247
Pubmed	Metaplastic thymoma: a distinctive thymic neoplasm characterized by YAP1-MAML2 gene fusions.	MAML2 YAP1	9.28e-07	2	34	2	31641231
Pubmed	Transcription factor FoxO1 is essential for enamel biomineralization.	FOXO1 SMAD3	9.28e-07	2	34	2	22291941
Pubmed	CARM1 inhibition reduces histone acetyltransferase activity causing synthetic lethality in CREBBP/EP300-mutated lymphomas.	CREBBP EP300	9.28e-07	2	34	2	32576962
Pubmed	Syndromic features and mild cognitive impairment in mice with genetic reduction on p300 activity: Differential contribution of p300 and CBP to Rubinstein-Taybi syndrome etiology.	CREBBP EP300	9.28e-07	2	34	2	19822209
Pubmed	Smad Anchor for Receptor Activation and Phospho-Smad3 Were Upregulated in Patients with Temporal Lobe Epilepsy.	ZFYVE9 SMAD3	9.28e-07	2	34	2	30847724
Pubmed	A specific CBP/p300-dependent gene expression programme drives the metabolic remodelling in late stages of spermatogenesis.	CREBBP EP300	9.28e-07	2	34	2	24522976
Pubmed	Recurrent YAP1::MAML2 fusions in "nodular necrotizing" variants of myxoinflammatory fibroblastic sarcoma: a comprehensive study of 7 cases.	MAML2 YAP1	9.28e-07	2	34	2	35546636
Pubmed	Histone acetyltransferase activities of cAMP-regulated enhancer-binding protein and p300 in tissues of fetal, young, and old mice.	CREBBP EP300	9.28e-07	2	34	2	11867645
Pubmed	CBP is required for environmental enrichment-induced neurogenesis and cognitive enhancement.	CREBBP EP300	9.28e-07	2	34	2	21847097
Pubmed	Dissecting the role of SWI/SNF component ARID1B in steady-state hematopoiesis.	ARID1B ARID1A	9.28e-07	2	34	2	37611161
Pubmed	Expression of the nuclear coactivators CBP and p300 in developing craniofacial tissue.	CREBBP EP300	9.28e-07	2	34	2	11963968
Pubmed	Subunits of ARID1 serve as novel biomarkers for the sensitivity to immune checkpoint inhibitors and prognosis of advanced non-small cell lung cancer.	ARID1B ARID1A	9.28e-07	2	34	2	32791957
Pubmed	ARID1B as a Potential Therapeutic Target for ARID1A-Mutant Ovarian Clear Cell Carcinoma.	ARID1B ARID1A	9.28e-07	2	34	2	29890703
Pubmed	p300 or CBP is required for insulin-stimulated glucose uptake in skeletal muscle and adipocytes.	CREBBP EP300	9.28e-07	2	34	2	34813504
Pubmed	Differential transcriptional activation by human T-cell leukemia virus type 1 Tax mutants is mediated by distinct interactions with CREB binding protein and p300.	CREBBP EP300	9.28e-07	2	34	2	9528808
Pubmed	UPF1 regulates FOXO1 protein expression by promoting PBK transcription in non-small cell lung cancer.	FOXO1 UPF1	9.28e-07	2	34	2	37167719
Pubmed	Analysis of genetic stability at the EP300 and CREBBP loci in a panel of cancer cell lines.	CREBBP EP300	9.28e-07	2	34	2	12696060
Pubmed	p300 interacts with the nuclear proto-oncoprotein SYT as part of the active control of cell adhesion.	SS18 EP300	9.28e-07	2	34	2	11030627
Pubmed	Angiomotin-like 1 plays a tumor-promoting role in glioma by enhancing the activation of YAP1 signaling.	YAP1 AMOTL1	9.28e-07	2	34	2	34480788
Pubmed	Rubinstein-Taybi Syndrome	CREBBP EP300	9.28e-07	2	34	2	20301699
Pubmed	CBP Is Required for Establishing Adaptive Gene Programs in the Adult Mouse Brain.	CREBBP EP300	9.28e-07	2	34	2	36109165
Pubmed	Potential biomarker of metformin action.	CREBBP EP300	9.28e-07	2	34	2	24639469
Pubmed	The histone acetyl transferases CBP and p300 regulate stress response pathways in synovial fibroblasts at transcriptional and functional levels.	CREBBP EP300	9.28e-07	2	34	2	37816914
Pubmed	ARID1A-mutated cervical cancer depends on the activation of YAP signaling.	ARID1A YAP1	9.28e-07	2	34	2	34994156
Pubmed	Retinoids and retinoic acid receptors regulate growth arrest and apoptosis in human mammary epithelial cells and modulate expression of CBP/p300.	CREBBP EP300	9.28e-07	2	34	2	12242694
Pubmed	Binding of p300/CBP co-activators by polyoma large T antigen.	CREBBP EP300	9.28e-07	2	34	2	11438528
Interaction	TBXT interactions	KMT2C ARID1B CHD7 BCL9 ARID1A SS18 CREBBP YAP1 EP300 SS18L1	2.23e-15	116	33	10	int:TBXT
Interaction	PAX8 interactions	KMT2C ARID1B CHD7 BCL9 ARID1A CREBBP EP300 SS18L1 SMAD3	1.16e-13	111	33	9	int:PAX8
Interaction	PAX7 interactions	KMT2C ARID1B CHD7 BCL9 ARID1A SS18 CREBBP EP300 SS18L1	3.21e-13	124	33	9	int:PAX7
Interaction	HNF4A interactions	MED14 FOXO1 KMT2C ARID1B CHD7 ARID1A SS18 CREBBP EP300 SS18L1 SMAD3	3.71e-13	275	33	11	int:HNF4A
Interaction	SOX9 interactions	KMT2C ARID1B CHD7 BCL9 ARID1A CREBBP EP300 SMAD3	2.70e-12	97	33	8	int:SOX9
Interaction	SMARCA4 interactions	FOXO1 ARID1B CHD7 CHD4 UPF1 ARID1A SS18 CREBBP YAP1 EP300 SS18L1 SMAD3	4.19e-12	462	33	12	int:SMARCA4
Interaction	ARID1A interactions	ARID1B CHD7 CHD4 ARID1A SS18 CREBBP YAP1 EP300 SS18L1 SMAD3	1.38e-11	276	33	10	int:ARID1A
Interaction	GCM1 interactions	KMT2C ARID1B BCL9 ARID1A SS18 CREBBP EP300	1.44e-11	68	33	7	int:GCM1
Interaction	MYOD1 interactions	KMT2C ARID1B BCL9 ARID1A SS18 CREBBP EP300 SS18L1 SMAD3	1.86e-11	194	33	9	int:MYOD1
Interaction	KLF5 interactions	KMT2C ARID1B BCL9 ARID1A SS18 CREBBP YAP1 EP300 SMAD3	1.95e-11	195	33	9	int:KLF5
Interaction	FEV interactions	KMT2C ARID1B CHD7 BCL9 ARID1A CREBBP YAP1 EP300 SS18L1	2.80e-11	203	33	9	int:FEV
Interaction	YAP1 interactions	MED14 FOXO1 KMT2C ARID1B CHD4 TAB1 UPF1 ARID1A NFAT5 GCN1 CREBBP YAP1 EP300 SMAD3 AMOTL1	3.98e-11	1095	33	15	int:YAP1
Interaction	FOS interactions	KMT2C ARID1B BCL9 ARID1A NFAT5 SS18 CREBBP EP300 SS18L1 SMAD3	4.63e-11	312	33	10	int:FOS
Interaction	ERG interactions	KMT2C ARID1B CHD7 BCL9 ARID1A SS18 CREBBP EP300 SS18L1	6.48e-11	223	33	9	int:ERG
Interaction	FOXI1 interactions	KMT2C ARID1B BCL9 ARID1A CREBBP YAP1 EP300	1.27e-10	92	33	7	int:FOXI1
Interaction	SMARCC2 interactions	ARID1B CHD7 CHD4 ARID1A SS18 CREBBP YAP1 EP300 SS18L1 SMAD3	1.55e-10	353	33	10	int:SMARCC2
Interaction	SS18L1 interactions	ARID1B ARID1A SS18 CREBBP EP300 SS18L1 SMAD3	1.99e-10	98	33	7	int:SS18L1
Interaction	CRX interactions	KMT2C ARID1B CHD7 BCL9 ARID1A CREBBP EP300 SS18L1 SMAD3	2.06e-10	254	33	9	int:CRX
Interaction	EGR2 interactions	KMT2C ARID1B CHD7 BCL9 ARID1A CREBBP EP300 SS18L1	2.64e-10	171	33	8	int:EGR2
Interaction	SMARCC1 interactions	ARID1B CHD7 CHD4 ARID1A SS18 CREBBP YAP1 EP300 SS18L1 SMAD3	3.52e-10	384	33	10	int:SMARCC1
Interaction	HNF1B interactions	KMT2C ARID1B CHD7 BCL9 ARID1A CREBBP YAP1 EP300	6.11e-10	190	33	8	int:HNF1B
Interaction	GATA2 interactions	KMT2C ARID1B CHD7 BCL9 ARID1A SS18 CREBBP EP300	8.82e-10	199	33	8	int:GATA2
Interaction	SP7 interactions	KMT2C ARID1B CHD7 BCL9 ARID1A SS18 CREBBP EP300 SS18L1	1.01e-09	304	33	9	int:SP7
Interaction	ETV4 interactions	ARID1B BCL9 ARID1A SS18 CREBBP EP300	1.33e-09	69	33	6	int:ETV4
Interaction	AR interactions	MED14 FOXO1 KMT2C ARID1B CHD7 CHD4 BCL9 ARID1A GCN1 CREBBP YAP1 EP300 SMAD3	2.11e-09	992	33	13	int:AR
Interaction	E2F5 interactions	ARID1B ARID1A CREBBP EP300 SMAD3	3.12e-09	36	33	5	int:E2F5
Interaction	ELF5 interactions	KMT2C ARID1B CHD7 ARID1A SS18 EP300 SS18L1	3.47e-09	147	33	7	int:ELF5
Interaction	SOX7 interactions	KMT2C ARID1B CHD7 ARID1A CREBBP EP300	3.82e-09	82	33	6	int:SOX7
Interaction	IRF4 interactions	KMT2C ARID1B CHD7 ARID1A SS18 EP300	4.76e-09	85	33	6	int:IRF4
Interaction	SMARCB1 interactions	KMT2C ARID1B CHD4 ARID1A SS18 CREBBP YAP1 EP300 SS18L1	4.88e-09	364	33	9	int:SMARCB1
Interaction	PAX6 interactions	KMT2C ARID1B CHD7 BCL9 ARID1A CREBBP EP300 SS18L1 SMAD3	5.12e-09	366	33	9	int:PAX6
Interaction	GSC interactions	KMT2C ARID1B BCL9 CREBBP EP300 SMAD3	5.48e-09	87	33	6	int:GSC
Interaction	KLF4 interactions	KMT2C ARID1B UPF1 BCL9 ARID1A CREBBP EP300	6.26e-09	160	33	7	int:KLF4
Interaction	SOX17 interactions	KMT2C ARID1B CHD7 BCL9 ARID1A SS18	9.35e-09	95	33	6	int:SOX17
Interaction	GATA1 interactions	MED14 ARID1B CHD4 BCL9 ARID1A CREBBP EP300	9.93e-09	171	33	7	int:GATA1
Interaction	TLX1 interactions	KMT2C ARID1B CHD7 BCL9 ARID1A CREBBP EP300	1.17e-08	175	33	7	int:TLX1
Interaction	TEAD1 interactions	KMT2C ARID1B CHD7 ARID1A CREBBP YAP1 EP300	1.21e-08	176	33	7	int:TEAD1
Interaction	ARID1B interactions	ARID1B ARID1A SS18 CREBBP YAP1 SS18L1 SMAD3	1.26e-08	177	33	7	int:ARID1B
Interaction	DDX5 interactions	FOXO1 CHD4 UPF1 MBD5 CREBBP YAP1 STAG2 EP300 ARAF SMAD3	1.51e-08	568	33	10	int:DDX5
Interaction	SMARCE1 interactions	ARID1B CHD7 CHD4 ARID1A SS18 YAP1 EP300 SS18L1	1.56e-08	287	33	8	int:SMARCE1
Interaction	ACTL6A interactions	MED14 ARID1B CHD4 ARID1A SS18 YAP1 EP300 SS18L1	1.65e-08	289	33	8	int:ACTL6A
Interaction	LHX3 interactions	KMT2C ARID1B CHD7 BCL9 ARID1A CREBBP SS18L1	1.71e-08	185	33	7	int:LHX3
Interaction	CREBBP interactions	FOXO1 ARID1B MAML2 ARID1A CLOCK CREBBP YAP1 EP300 SS18L1 SMAD3	2.49e-08	599	33	10	int:CREBBP
Interaction	TBR1 interactions	KMT2C ARID1B CHD7 BCL9 ARID1A EP300	2.66e-08	113	33	6	int:TBR1
Interaction	SMAD3 interactions	FOXO1 ARID1B ZFYVE9 ARID1A CREBBP YAP1 EP300 SS18L1 SMAD3	2.88e-08	447	33	9	int:SMAD3
Interaction	ETS1 interactions	ARID1B ARID1A CREBBP EP300 SS18L1 SMAD3	4.01e-08	121	33	6	int:ETS1
Interaction	PAX9 interactions	KMT2C ARID1B CHD7 BCL9 ARID1A EP300	6.16e-08	130	33	6	int:PAX9
Interaction	SMARCA2 interactions	ARID1B CHD4 ARID1A SS18 CREBBP YAP1 EP300 SS18L1	6.65e-08	346	33	8	int:SMARCA2
Interaction	SMAD1 interactions	MED14 ARID1A CREBBP YAP1 EP300 SS18L1 SMAD3	1.11e-07	243	33	7	int:SMAD1
Interaction	EP300 interactions	FOXO1 CHD4 MAML2 UPF1 ARID1A CLOCK SS18 GCN1 CREBBP YAP1 EP300 SS18L1 SMAD3	1.29e-07	1401	33	13	int:EP300
Interaction	SMAD2 interactions	KMT2C ARID1B ZFYVE9 ARID1A CREBBP YAP1 EP300 SMAD3	1.51e-07	385	33	8	int:SMAD2
Interaction	SOX2 interactions	KMT2C ARID1B CHD7 CHD4 UPF1 BCL9 ARID1A CLOCK SS18 GCN1 YAP1 STAG2 EP300	1.53e-07	1422	33	13	int:SOX2
Interaction	ARID2 interactions	ARID1B CHD7 ARID1A SS18 YAP1 SS18L1	1.62e-07	153	33	6	int:ARID2
Interaction	IRF1 interactions	ARID1B ARID1A SS18 CREBBP EP300	2.27e-07	83	33	5	int:IRF1
Interaction	NR3C1 interactions	MED14 ARID1B CHD7 BCL9 ARID1A SS18 CREBBP STAG2 EP300 SS18L1 SMAD3	2.31e-07	974	33	11	int:NR3C1
Interaction	WWTR1 interactions	ARID1B ARID1A CLOCK GCN1 CREBBP YAP1 EP300 AMOTL1	3.04e-07	422	33	8	int:WWTR1
Interaction	SS18 interactions	ARID1B ARID1A SS18 EP300 SS18L1	3.05e-07	88	33	5	int:SS18
Interaction	CEBPA interactions	MED14 KMT2C ARID1B CHD7 CHD4 UPF1 BCL9 ARID1A CREBBP STAG2 EP300 SMAD3	3.09e-07	1245	33	12	int:CEBPA
Interaction	EPAS1 interactions	MED14 ARID1B CHD4 CREBBP EP300 SMAD3	3.35e-07	173	33	6	int:EPAS1
Interaction	TLX3 interactions	TBX18 KMT2C ARID1B CHD7 BCL9 ARID1A EP300	3.77e-07	291	33	7	int:TLX3
Interaction	SOX10 interactions	ARID1B CHD7 BCL9 ARID1A EP300	3.81e-07	92	33	5	int:SOX10
Interaction	DPF3 interactions	ARID1B ARID1A SS18 EP300 SS18L1	4.47e-07	95	33	5	int:DPF3
Interaction	LHX2 interactions	KMT2C ARID1B CHD7 BCL9 ARID1A SS18	4.67e-07	183	33	6	int:LHX2
Interaction	SMARCD2 interactions	MED14 ARID1B CHD4 ARID1A SS18 SS18L1	4.67e-07	183	33	6	int:SMARCD2
Interaction	GATA3 interactions	ARID1B CHD7 BCL9 ARID1A CREBBP EP300	5.30e-07	187	33	6	int:GATA3
Interaction	PPARG interactions	MED14 FOXO1 KMT2C ARID1B CREBBP EP300 SMAD3	5.41e-07	307	33	7	int:PPARG
Interaction	NFIA interactions	ARID1B BCL9 ARID1A CREBBP EP300 SMAD3	5.47e-07	188	33	6	int:NFIA
Interaction	PROX1 interactions	CHD4 CREBBP EP300 SMAD3	5.78e-07	41	33	4	int:PROX1
Interaction	LHX1 interactions	KMT2C ARID1B CHD7 BCL9 ARID1A	6.70e-07	103	33	5	int:LHX1
Interaction	KDM2A interactions	CREBBP YAP1 STAG2 EP300 SMAD3	6.70e-07	103	33	5	int:KDM2A
Interaction	JUP interactions	FOXO1 CHD4 ZFYVE9 MBD5 CREBBP YAP1 EP300 ARAF	8.69e-07	485	33	8	int:JUP
Interaction	BRD9 interactions	MED14 ARID1B ARID1A SS18 SS18L1	1.26e-06	117	33	5	int:BRD9
Interaction	DDIT3 interactions	ARID1B ARID1A SS18 CREBBP EP300	1.43e-06	120	33	5	int:DDIT3
Interaction	RARA interactions	FOXO1 ARID1A CLOCK CREBBP EP300 SMAD3	1.48e-06	223	33	6	int:RARA
Interaction	PML interactions	FOXO1 CHD4 TAB1 UPF1 ZFYVE9 GCN1 CREBBP YAP1 EP300 SMAD3	1.51e-06	933	33	10	int:PML
Interaction	SNAI1 interactions	CHD4 TAB1 UPF1 GCN1 CREBBP YAP1 EP300 SMAD3	2.11e-06	546	33	8	int:SNAI1
Interaction	RBM14 interactions	FOXO1 CHD4 SS18 YAP1 STAG2 EP300 ARAF SMAD3	2.32e-06	553	33	8	int:RBM14
Interaction	RARG interactions	ARID1A YAP1 EP300 SMAD3	2.37e-06	58	33	4	int:RARG
Interaction	FUS interactions	FOXO1 CHD4 UPF1 ARID1A SS18 CREBBP YAP1 EP300 ARAF	2.43e-06	757	33	9	int:FUS
Interaction	MAML2 interactions	MAML2 CREBBP EP300	2.68e-06	17	33	3	int:MAML2
Interaction	FHL2 interactions	FOXO1 ZFYVE9 NFAT5 CREBBP EP300 SMAD3 AMOTL1	2.95e-06	396	33	7	int:FHL2
Interaction	FLI1 interactions	ARID1B ARID1A SS18 SMAD3	3.11e-06	62	33	4	int:FLI1
Interaction	SOX15 interactions	ARID1B UPF1 BCL9 ARID1A EP300	3.16e-06	141	33	5	int:SOX15
Interaction	ARNT interactions	FOXO1 CHD4 CLOCK CREBBP YAP1 EP300	3.22e-06	255	33	6	int:ARNT
Interaction	NFIB interactions	KMT2C ARID1B BCL9 ARID1A CREBBP	3.28e-06	142	33	5	int:NFIB
Interaction	TLX2 interactions	KMT2C ARID1B CHD7 BCL9 ARID1A	3.28e-06	142	33	5	int:TLX2
Interaction	PBRM1 interactions	ARID1B CHD7 CHD4 ARID1A SS18 SS18L1	3.44e-06	258	33	6	int:PBRM1
Interaction	H2BC3 interactions	KMT2C CHD7 CHD4 CREBBP YAP1 STAG2 EP300	3.48e-06	406	33	7	int:H2BC3
Interaction	SUPT5H interactions	MED14 ARID1B CHD7 CHD4 ZFYVE9 ARID1A EP300	3.59e-06	408	33	7	int:SUPT5H
Interaction	NCOA6 interactions	KMT2C CREBBP YAP1 EP300 SMAD3	3.63e-06	145	33	5	int:NCOA6
Interaction	NCOA1 interactions	FOXO1 ARID1A CREBBP EP300 SMAD3	3.75e-06	146	33	5	int:NCOA1
Interaction	GATA4 interactions	CHD7 CHD4 UPF1 ARID1A SS18 EP300 SMAD3	3.77e-06	411	33	7	int:GATA4
Interaction	BICRA interactions	ARID1B ARID1A SS18 SS18L1	4.25e-06	67	33	4	int:BICRA
Interaction	PARP1 interactions	MED14 FOXO1 CHD7 CHD4 MBD5 CREBBP YAP1 STAG2 EP300 ARAF SMAD3	4.48e-06	1316	33	11	int:PARP1
Interaction	PLAGL1 interactions	CREBBP EP300 SMAD3	5.21e-06	21	33	3	int:PLAGL1
Interaction	MTA2 interactions	CHD7 CHD4 ARID1A YAP1 STAG2 EP300 SMAD3	5.47e-06	435	33	7	int:MTA2
Interaction	BAG2 interactions	FOXO1 CHD4 TAB1 CREBBP YAP1 EP300 ARAF MBNL3	5.52e-06	622	33	8	int:BAG2
Interaction	HIF1A interactions	MED14 CHD4 GCN1 CREBBP YAP1 EP300 SMAD3	5.98e-06	441	33	7	int:HIF1A
Interaction	MBD2 interactions	MED14 CHD4 ARID1A CREBBP STAG2	6.06e-06	161	33	5	int:MBD2
Interaction	ADAR interactions	CHD4 UPF1 GCN1 YAP1 STAG2 EP300	6.22e-06	286	33	6	int:ADAR
Cytoband	Ensembl 112 genes in cytogenetic band chr11q21	MAML2 AMOTL1	1.01e-03	63	34	2	chr11q21
GeneFamily	Zinc fingers ZZ-type\|Lysine acetyltransferases	CLOCK CREBBP EP300	9.09e-07	17	21	3	486
GeneFamily	AT-rich interaction domain containing	ARID1B ARID1A	1.34e-04	15	21	2	418
GeneFamily	Zinc fingers ZZ-type\|Lysine acetyltransferases	CREBBP EP300	1.94e-04	18	21	2	91
GeneFamily	PHD finger proteins	KMT2C CHD4	4.84e-03	90	21	2	88
Coexpression	GSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_TREATED_WITH_DIGOXIN_UP	KMT2C CHD7 ARID1A NFAT5 CREBBP EP300	1.11e-07	180	34	6	M8239
Coexpression	GRESHOCK_CANCER_COPY_NUMBER_UP	FOXO1 MAML2 BCL9 SS18 CREBBP EP300 SS18L1	1.64e-07	323	34	7	M9150
Coexpression	CUI_TCF21_TARGETS_2_DN	KMT2C MBD5 CLOCK CREBBP STAG2 EP300 ARAF MBNL3 AMOTL1	1.00e-06	854	34	9	M1533
Coexpression	CUI_TCF21_TARGETS_2_DN	KMT2C MBD5 CLOCK CREBBP STAG2 EP300 ARAF MBNL3 AMOTL1	1.38e-06	888	34	9	MM1018
Coexpression	GSE14350_TREG_VS_TEFF_UP	ARID1B MBD5 CLOCK SMAD3 RAB11FIP2	5.58e-06	199	34	5	M3417
Coexpression	XIE_TRASTUZUMAB_CARDIOTOXICITY_MMU_MIR_329_3P_GENES	ARID1B USF3 SS18	1.27e-05	35	34	3	MM17501
Coexpression	LAKE_ADULT_KIDNEY_C15_CONNECTING_TUBULE	KMT2C MAML2 NFAT5 YAP1	6.96e-05	171	34	4	M39234
Coexpression	GSE13738_RESTING_VS_BYSTANDER_ACTIVATED_CD4_TCELL_UP	KMT2C MAML2 BCL9 STAG2	1.13e-04	194	34	4	M3321
Coexpression	GSE46606_IRF4_KO_VS_WT_CD40L_IL2_IL5_3DAY_STIMULATED_BCELL_DN	KMT2C CHD4 UPF1 CREBBP	1.16e-04	195	34	4	M9824
Coexpression	GSE12366_PLASMA_CELL_VS_NAIVE_BCELL_DN	MED14 ARID1A STAG2 MBNL3	1.25e-04	199	34	4	M3175
Coexpression	GSE8921_UNSTIM_0H_VS_TLR1_2_STIM_MONOCYTE_6H_DN	MED14 SS18 MBNL3 RAB11FIP2	1.28e-04	200	34	4	M6404
Coexpression	GSE43863_TH1_VS_TFH_EFFECTOR_CD4_TCELL_DN	ARID1A CLOCK CREBBP RAB11FIP2	1.28e-04	200	34	4	M9763
Coexpression	GSE7460_CTRL_VS_TGFB_TREATED_ACT_CD8_TCELL_DN	FOXO1 CREBBP SS18L1 RAB11FIP2	1.28e-04	200	34	4	M5679
Coexpression	HEVNER_VENTRICULAR_ZONE_AND_UP_NEURON_FATE_COMMITTED_CELLS	ARID1B SS18L1	1.70e-04	15	34	2	MM410
Coexpression	IVANOVSKA_MIR106B_TARGETS	ZFYVE9 CLOCK GOLGA1	2.10e-04	89	34	3	M2258
Coexpression	NAKAYA_PBMC_FLUMIST_AGE_18_50YO_3DY_DN	MED14 FOXO1 CHD7 EP300 ARAF RAB11FIP2	2.16e-04	680	34	6	M41089
Coexpression	SUZUKI_AMPLIFIED_IN_ORAL_CANCER	BCL9 YAP1	2.19e-04	17	34	2	M15351
Coexpression	BENPORATH_NANOG_TARGETS	FOXO1 ARID1B BCL9 NFAT5 YAP1 SMAD3 AMOTL1	2.33e-04	988	34	7	M6616
Coexpression	PUJANA_BREAST_CANCER_LIT_INT_NETWORK	CREBBP EP300 SMAD3	3.05e-04	101	34	3	M15356
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN	ZFYVE9 CLOCK CREBBP YAP1 SMAD3	3.16e-04	466	34	5	M13522
Coexpression	NAKAYA_MYELOID_DENDRITIC_CELL_FLUARIX_FLUVIRIN_AGE_18_50YO_7DY_DN	CHD4 TAB1 SMAD3 RAB11FIP2	3.95e-04	269	34	4	M41203
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_2500_k-means-cluster#4	MED14 CHD7 CHD4 ZFYVE9 ARID1A CLOCK STAG2 EP300	2.71e-06	595	33	8	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_2500_K4
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-5\|TCGA-Ovary / Sample_Type by Project: Shred V9	ARID1B CHD4 USF3 ARID1A MBD5	1.64e-07	166	34	5	32d2eaf8a5d03881bf74d680825af2d5110b082d
ToppCell	pdx\|World / Sample and Cell Type and Tumor Cluster (all cells)	ARID1B ARID1A NFAT5 YAP1 MBNL3	2.89e-07	186	34	5	de8e538c8767d41b8a52f5e58ba1affd4e7244c4
ToppCell	pdx-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	ARID1B ARID1A NFAT5 YAP1 MBNL3	2.89e-07	186	34	5	0b88a87158a9ca8de3bf40a4ff1687150707a5f0
ToppCell	nucseq\|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	FOXO1 KMT2C ARID1B MAML2 NFAT5	3.47e-07	193	34	5	779276e775cb2492e8dd36436295a536084a6415
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	USF3 BCL9 ARID1A CLOCK STAG2	3.47e-07	193	34	5	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	RA-02._Fibroblast_II\|World / Chamber and Cluster_Paper	FOXO1 TBX18 ARID1B MAML2 SMAD3	3.74e-07	196	34	5	e8cbda03837f1f26470a9d93aa7fdaa04e08e38a
ToppCell	356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	USF3 MAML2 UPF1 MBNL3	9.36e-06	175	34	4	f3a68aeb79c4935006e17a5ff3445a8ec0e33f5f
ToppCell	RA-01._Fibroblast_I\|World / Chamber and Cluster_Paper	FOXO1 TBX18 MAML2 SMAD3	1.07e-05	181	34	4	2b6ddeb53a79a658e2ba78527ff48c155b20daa6
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1\|TCGA-Pancreas / Sample_Type by Project: Shred V9	MED14 NFAT5 CREBBP EP300	1.19e-05	186	34	4	03db813598b67b1e08f759758a1c2023396921fa
ToppCell	-Unknown\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FOXO1 ZFYVE9 CLOCK SMAD3	1.24e-05	188	34	4	9cb718bfe1358c6fd842f096e228eb0abb9aefc6
ToppCell	-Unknown-Endothelial-Myofibroblast\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FOXO1 ZFYVE9 CLOCK SMAD3	1.24e-05	188	34	4	6468fa95ad0395395301115286f2d8c0df5d3882
ToppCell	-Unknown-Endothelial\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FOXO1 ZFYVE9 CLOCK SMAD3	1.24e-05	188	34	4	7a81ac5c79c3eb26639b52d2b9fd5e7ef9798fd6
ToppCell	renal_medulla_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	ARID1B MAML2 MBD5 NFAT5	1.27e-05	189	34	4	830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FOXO1 CHD7 MAML2 YAP1	1.29e-05	190	34	4	2de8e4cfeee350a9a76af749d6ce58d948c129b8
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FOXO1 CHD7 MAML2 YAP1	1.32e-05	191	34	4	f3158cedf67e3b90aa94ea1f61c72c33aaa2d5ba
ToppCell	renal_cortex_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	FOXO1 ARID1B MAML2 MBD5	1.35e-05	192	34	4	e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCell	RA-02._Fibroblast_II\|RA / Chamber and Cluster_Paper	FOXO1 ARID1B MAML2 SMAD3	1.43e-05	195	34	4	6a02ebbeb3199447ddce64d92d8809436e040eba
ToppCell	Bronchial-NucSeq\|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations	ARID1B MAML2 MBD5 YAP1	1.46e-05	196	34	4	ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCell	Parenchymal-NucSeq\|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations	ARID1B MAML2 MBD5 YAP1	1.52e-05	198	34	4	1996373bdccc55aac347d349bd22f6aad6d0c668
ToppCell	Tracheal-NucSeq\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	KMT2C ARID1B MAML2 MBD5	1.55e-05	199	34	4	94b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell	Macroglial\|World / cells hierarchy compared to all cells using T-Statistic	FOXO1 CHD7 MAML2 YAP1	1.58e-05	200	34	4	e6935ad49216d2500c15c05cbc2b89402c65e838
ToppCell	Mild/Remission-B_naive-4\|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)	FOXO1 USF3 CREBBP	2.86e-04	169	34	3	c3a6179a64589a370108fea809b157839347759c
ToppCell	356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	MAML2 UPF1 MBNL3	3.01e-04	172	34	3	a9e13aa36087170dadca421ba9de588e5a1cf715
ToppCell	droplet-Marrow-nan-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHD4 STAG2 EP300	3.67e-04	184	34	3	1154a5ad7b8512272b7476f949ddac350910bfb7
ToppCell	droplet-Marrow-nan-3m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHD4 STAG2 EP300	3.73e-04	185	34	3	7adfa929930cfa795cbfbd9f1a0b439e08aa765d
ToppCell	pdx-Tumor_cells-T0\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	NFAT5 YAP1 SMAD3	3.73e-04	185	34	3	1d874608aa2062024323512f68889219471b2f00
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1_FGFR3_MT1G\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FOXO1 MAML2 YAP1	3.79e-04	186	34	3	41e03be964044dae690d566bd078dab3d8045eba
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Astro-Astrocyte\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FOXO1 MAML2 YAP1	3.85e-04	187	34	3	5c73010fe4c85fb5cc1273f5504821229ca0cc4b
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Astro\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FOXO1 MAML2 YAP1	3.85e-04	187	34	3	5d3d68519c8e19f10c29f9d81712125be78ca15a
ToppCell	human_hepatoblastoma-Tumor_cells-T2\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	MBD5 YAP1 MBNL3	3.85e-04	187	34	3	f3e37c18ac6471c7992609bbddfa4975571c815c
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	KMT2C ARID1B NFAT5	3.91e-04	188	34	3	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6-Inh_L1_PAX6_CA4\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FOXO1 MAML2 AMOTL1	3.91e-04	188	34	3	ee572246e0c2f41bdbc29a03edc67b831af95c09
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FOXO1 CHD7 MAML2	3.91e-04	188	34	3	505b6b4277d7dea87aee27191d0acca67928b8e6
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NFAT5 YAP1 RAB11FIP2	3.97e-04	189	34	3	90aae7e806882bebfad78a78e9a16cf56af3ecd4
ToppCell	343B-Lymphocytic-ILC\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	CHD4 USF3 TAB1	3.97e-04	189	34	3	c26428871dc3261327d89cacaba6e21e004ff1f3
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Neuronal-Immature_INs\|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.	AMBN ARID1B CHD7	4.03e-04	190	34	3	842760bfe0a52e67bad800efa7d99448a4a23ebb
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FOXO1 CHD7 MAML2	4.09e-04	191	34	3	a90c8ab2077e52bbc998457c85a1b9867f9c8c93
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FOXO1 CHD7 MAML2	4.09e-04	191	34	3	2b056cbe2e82e056e1f798974999378460eb1d16
ToppCell	RV-01._Fibroblast_I\|World / Chamber and Cluster_Paper	FOXO1 MAML2 SMAD3	4.09e-04	191	34	3	70c067c54084bfb02c29bab085f4defd477194fb
ToppCell	RV-01._Fibroblast_I\|RV / Chamber and Cluster_Paper	FOXO1 MAML2 SMAD3	4.15e-04	192	34	3	356160b113c3305a61ceeaff33ce3c9da0be2878
ToppCell	human_hepatoblastoma-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	ARID1B MBD5 NFAT5	4.15e-04	192	34	3	916fbec1c7ab7969bda711886ac88e877e30c280
ToppCell	human_hepatoblastoma\|World / Sample and Cell Type and Tumor Cluster (all cells)	ARID1B MBD5 NFAT5	4.22e-04	193	34	3	e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCell	LV-01._Fibroblast_I\|LV / Chamber and Cluster_Paper	FOXO1 TBX18 MAML2	4.22e-04	193	34	3	dc17f3b9758936d428cf17f77a1ce6d4c479b165
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	NFAT5 YAP1 SMAD3	4.28e-04	194	34	3	abacb6a8d7a9003f2f6c2be0305507f1c1c50347
ToppCell	RV-02._Fibroblast_II\|RV / Chamber and Cluster_Paper	FOXO1 MAML2 SMAD3	4.28e-04	194	34	3	11c79a8c56ece42713b04b321982e41e239f07a5
ToppCell	LA-02._Fibroblast_II\|LA / Chamber and Cluster_Paper	FOXO1 MAML2 SMAD3	4.28e-04	194	34	3	234d1494c114cce77c619708bbcd8d5ce805f19b
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	NFAT5 YAP1 SMAD3	4.28e-04	194	34	3	46070fbb0ee0eb9e1801c43b73a15707471056dc
ToppCell	COVID-19-Heart-Fib_1\|Heart / Disease (COVID-19 only), tissue and cell type	TBX18 MAML2 SMAD3	4.35e-04	195	34	3	f423baa36ac7cdc383c033e35a7d17e6bf913323
ToppCell	RV-02._Fibroblast_II\|World / Chamber and Cluster_Paper	FOXO1 MAML2 SMAD3	4.35e-04	195	34	3	ce90b30dcdb56d4cd925cdb79fd9d7cefd998f48
ToppCell	LA-02._Fibroblast_II\|World / Chamber and Cluster_Paper	FOXO1 MAML2 SMAD3	4.35e-04	195	34	3	a78b605b49acd8c9d68716266ca269dafcd910b9
ToppCell	COVID-19_Severe-CD4+_T_naive\|COVID-19_Severe / Disease condition and Cell class	FOXO1 CHD7 MAML2	4.48e-04	197	34	3	ac26672bd2cb3bc9a11206d8da203bafec3931f6
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-1_mon-Proliferating-Cycling_Progenitors\|1_mon / Sample Type, Dataset, Time_group, and Cell type.	ARID1A YAP1 RAB11FIP2	4.61e-04	199	34	3	358c4b3037f59378db8916a2fbe9ed4830cf1449
ToppCell	COVID-19\|World / Disease, condition lineage and cell class	KMT2C ARID1B CHD4	4.68e-04	200	34	3	7dec470c379cd89f05a0f37c8628b21f136e52f0
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	ARID1A CREBBP YAP1 STAG2 EP300 SMAD3	2.51e-07	180	34	6	4821_DN
Drug	Ketotifen fumarate [34580-14-8]; Down 200; 9.4uM; MCF7; HT_HG-U133A	FOXO1 UPF1 ARID1A NFAT5 GOLGA1 RAB11FIP2	4.40e-07	198	34	6	7199_DN
Drug	Trichostatin A, Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA	ARID1A CREBBP YAP1 EP300 SMAD3	5.11e-06	170	34	5	1050_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	ARID1A CREBBP YAP1 EP300 SMAD3	5.56e-06	173	34	5	5987_DN
Drug	Trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	ARID1A CREBBP YAP1 EP300 SMAD3	5.72e-06	174	34	5	1659_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	ZFYVE9 ARID1A CREBBP YAP1 SMAD3	5.72e-06	174	34	5	5693_DN
Drug	SAHA; Down 200; 10uM; MCF7; HT_HG-U133A_EA	ARID1A CREBBP YAP1 EP300 SMAD3	5.88e-06	175	34	5	1058_DN
Drug	SAHA; Down 200; 10uM; MCF7; HT_HG-U133A	ARID1A CREBBP YAP1 STAG2 EP300	6.22e-06	177	34	5	1645_DN
Drug	Trichostatin A, Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA	ARID1A CREBBP YAP1 ARAF RAB11FIP2	6.39e-06	178	34	5	1112_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A	ARID1A CREBBP EP300 ARAF SMAD3	6.57e-06	179	34	5	5822_DN
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; PC3; HT_HG-U133A	ARID1A CREBBP STAG2 EP300 SMAD3	6.75e-06	180	34	5	6886_DN
Drug	Trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	ARID1A CREBBP YAP1 EP300 SMAD3	6.93e-06	181	34	5	6951_DN
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	ARID1A GCN1 YAP1 ARAF SMAD3	7.51e-06	184	34	5	6916_DN
Drug	SAHA; Down 200; 10uM; MCF7; HT_HG-U133A	ARID1A CREBBP YAP1 STAG2 SMAD3	7.51e-06	184	34	5	6939_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A	ZFYVE9 ARID1A CREBBP YAP1 SMAD3	7.71e-06	185	34	5	5882_DN
Drug	3'-dCTP	MED14 CREBBP STAG2 EP300	9.67e-06	90	34	4	CID000153054
Drug	paclitaxel; Down 200; 0.1uM; MCF7; HG-U133A	FOXO1 BCL9 OMG STAG2 EP300	9.71e-06	194	34	5	640_DN
Drug	Pirenzepine dihydrochloride [29868-97-1]; Down 200; 9.4uM; MCF7; HT_HG-U133A	TAB1 ZFYVE9 ARID1A NFAT5 GOLGA1	9.95e-06	195	34	5	2234_DN
Drug	Rifampicin [13292-46-1]; Up 200; 4.8uM; MCF7; HT_HG-U133A	ZFYVE9 BCL9 NFAT5 SS18 MBNL3	1.02e-05	196	34	5	2847_UP
Drug	Cefaclor [70356-03-5]; Up 200; 10.4uM; MCF7; HT_HG-U133A	TAB1 UPF1 ZFYVE9 BCL9 SMAD3	1.02e-05	196	34	5	2843_UP
Drug	Ribostamycin sulfate salt [53797-35-6]; Down 200; 7.2uM; MCF7; HT_HG-U133A	ARID1A SS18 GOLGA1 SMAD3 RAB11FIP2	1.05e-05	197	34	5	3444_DN
Drug	Mcat	YAP1 ARAF SMAD3	1.93e-05	35	34	3	CID003080785
Drug	3,4-dimethoxy-N-((2,2-dimethyl-2H-chromen-6-yl)methyl)-N-phenylbenzenesulfonamide	CREBBP EP300	2.16e-05	5	34	2	ctd:C575894
Drug	SYNOVIAL	SS18 ARAF	4.52e-05	7	34	2	CID000072095
Drug	MW 1	ZFYVE9 CREBBP EP300 SMAD3	7.38e-05	151	34	4	CID000073965
Drug	Butyric Acid	FOXO1 CHD4 CREBBP EP300	9.47e-05	161	34	4	ctd:D020148
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	ZFYVE9 ARID1A YAP1 SMAD3	1.04e-04	165	34	4	6085_DN
Drug	Trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	ARID1A YAP1 EP300 SMAD3	1.14e-04	169	34	4	5231_DN
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	ARID1A YAP1 EP300 SMAD3	1.17e-04	170	34	4	7043_DN
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	ARID1A CREBBP EP300 SMAD3	1.19e-04	171	34	4	6879_DN
Drug	Trichostatin A, Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	ARID1A CREBBP YAP1 ARAF	1.22e-04	172	34	4	1637_DN
Drug	Trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A_EA	ARID1A CREBBP EP300 SMAD3	1.22e-04	172	34	4	1072_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A	ARID1A SS18 EP300 SMAD3	1.25e-04	173	34	4	4237_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	ARID1A CLOCK CREBBP EP300	1.25e-04	173	34	4	2881_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	ARID1A CREBBP YAP1 SMAD3	1.28e-04	174	34	4	3462_DN
Drug	stannous fluoride	SS18 STAG2 SS18L1	1.31e-04	66	34	3	CID000024550
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A	ARID1A CREBBP SMAD3 RAB11FIP2	1.31e-04	175	34	4	6316_DN
Drug	Trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A_EA	ARID1A CREBBP EP300 SMAD3	1.31e-04	175	34	4	1014_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	ARID1A CREBBP YAP1 SMAD3	1.34e-04	176	34	4	3312_DN
Drug	trichostatin A ; Down 200; 1uM; MCF7; HT_HG-U133A_EA	CHD7 ARID1A CREBBP YAP1	1.34e-04	176	34	4	981_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	ARID1A CREBBP YAP1 SMAD3	1.34e-04	176	34	4	1535_DN
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	ARID1A CREBBP YAP1 EP300	1.36e-04	177	34	4	6434_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	ARID1A CREBBP EP300 SMAD3	1.36e-04	177	34	4	3227_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	ARID1A CREBBP YAP1 SMAD3	1.36e-04	177	34	4	3177_DN
Drug	Trichostatin A, Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA	ARID1A CLOCK CREBBP SMAD3	1.39e-04	178	34	4	992_DN
Drug	SAHA; Down 200; 10uM; PC3; HT_HG-U133A	ZFYVE9 ARID1A CREBBP EP300	1.39e-04	178	34	4	4444_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	ARID1A YAP1 EP300 RAB11FIP2	1.39e-04	178	34	4	4710_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A	ARID1A CREBBP GOLGA1 EP300	1.42e-04	179	34	4	6609_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HG-U133A	ARID1A CREBBP GOLGA1 SMAD3	1.52e-04	182	34	4	1951_DN
Drug	Rifabutin [72559-06-9]; Down 200; 4.8uM; PC3; HT_HG-U133A	UPF1 ZFYVE9 CREBBP GOLGA1	1.55e-04	183	34	4	4527_DN
Drug	Doxorubicin hydrochloride [25316-40-9]; Down 200; 6.8uM; MCF7; HT_HG-U133A	CHD7 ARID1A EP300 SMAD3	1.58e-04	184	34	4	5671_DN
Drug	Nifuroxazide [965-52-6]; Down 200; 14.6uM; MCF7; HT_HG-U133A	BCL9 NFAT5 SS18 ARAF	1.72e-04	188	34	4	4835_DN
Drug	Glucose	FOXO1 CHD7 CHD4 MBD5 CREBBP YAP1 STAG2 EP300 SMAD3	1.76e-04	1420	34	9	ctd:D005947
Drug	LY 294002; Up 200; 10uM; MCF7; HT_HG-U133A	BCL9 SS18 MBNL3 SMAD3	1.79e-04	190	34	4	6956_UP
Drug	haloperidol; Down 200; 10uM; MCF7; HT_HG-U133A	CHD4 TAB1 SS18 SMAD3	1.83e-04	191	34	4	5200_DN
Drug	Guanfacine hydrochloride [29110-48-3]; Down 200; 14.2uM; MCF7; HT_HG-U133A	MED14 NFAT5 SS18 GOLGA1	1.83e-04	191	34	4	2634_DN
Drug	Terazosin hydrochloride [63590-64-7]; Up 200; 9.4uM; MCF7; HT_HG-U133A	MED14 ZFYVE9 SS18 MBNL3	1.90e-04	193	34	4	7187_UP
Drug	Azaguanine-8 [134-58-7]; Down 200; 26.2uM; MCF7; HT_HG-U133A	CHD4 BCL9 SS18 GOLGA1	1.94e-04	194	34	4	1670_DN
Drug	Carbamazepine [298-46-4]; Up 200; 17uM; PC3; HT_HG-U133A	TAB1 ZFYVE9 NFAT5 SS18	1.94e-04	194	34	4	1805_UP
Drug	Guaifenesin [93-14-1]; Down 200; 20.2uM; MCF7; HT_HG-U133A	FOXO1 UPF1 NFAT5 SS18	1.94e-04	194	34	4	3431_DN
Drug	5279552; Down 200; 22uM; MCF7; HT_HG-U133A_EA	FOXO1 NFAT5 CREBBP EP300	1.98e-04	195	34	4	843_DN
Drug	Antazoline hydrochloride [2508-72-7]; Down 200; 13.2uM; MCF7; HT_HG-U133A	FOXO1 TAB1 MBNL3 SMAD3	1.98e-04	195	34	4	3173_DN
Drug	Testosterone propionate [57-85-2]; Down 200; 11.6uM; MCF7; HT_HG-U133A	UPF1 NFAT5 SS18 RAB11FIP2	1.98e-04	195	34	4	2649_DN
Drug	Flunarizine dihydrochloride [30484-77-6]; Up 200; 8.4uM; PC3; HT_HG-U133A	ZFYVE9 NFAT5 CREBBP GOLGA1	2.02e-04	196	34	4	7252_UP
Drug	Niridazole [61-57-4]; Up 200; 18.6uM; HL60; HT_HG-U133A	FOXO1 SS18 MBNL3 SMAD3	2.02e-04	196	34	4	2440_UP
Drug	Troleandomycin [2751-09-9]; Down 200; 5uM; PC3; HT_HG-U133A	TAB1 ARID1A SS18 SMAD3	2.02e-04	196	34	4	3985_DN
Drug	Pronethalol hydrochloride [51-02-5]; Down 200; 15uM; HL60; HT_HG-U133A	CHD4 UPF1 SS18 SMAD3	2.06e-04	197	34	4	2902_DN
Drug	Sulfachloropyridazine [80-32-0]; Down 200; 14uM; PC3; HT_HG-U133A	CHD7 ZFYVE9 SS18 SMAD3	2.06e-04	197	34	4	3769_DN
Drug	Carbachol [51-83-2]; Down 200; 21.8uM; HL60; HT_HG-U133A	SS18 GOLGA1 MBNL3 RAB11FIP2	2.06e-04	197	34	4	3042_DN
Drug	Moxisylyte hydrochoride [964-52-3]; Up 200; 12.6uM; MCF7; HT_HG-U133A	FOXO1 ZFYVE9 MBNL3 SMAD3	2.06e-04	197	34	4	1682_UP
Drug	Sulfaguanidine [57-67-0]; Down 200; 18.6uM; PC3; HG-U133A	ZFYVE9 ARID1A STAG2 SMAD3	2.10e-04	198	34	4	1913_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	ZFYVE9 ARID1A YAP1 EP300	2.10e-04	198	34	4	3332_DN
Drug	Levopropoxyphene napsylate [5714-90-9]; Up 200; 7.4uM; HL60; HT_HG-U133A	MED14 UPF1 ZFYVE9 SMAD3	2.10e-04	198	34	4	2980_UP
Drug	Tacrine hydrochloride hydrate [1684-40-8]; Down 200; 15.8uM; MCF7; HT_HG-U133A	ZFYVE9 ARID1A NFAT5 SS18	2.10e-04	198	34	4	2633_DN
Drug	Midecamycin [35457-80-8]; Down 200; 5uM; MCF7; HT_HG-U133A	MED14 ARID1A CREBBP SMAD3	2.10e-04	198	34	4	5345_DN
Drug	Y-27632; Down 200; 3uM; MCF7; HT_HG-U133A_EA	UPF1 BCL9 EP300 SMAD3	2.10e-04	198	34	4	948_DN
Drug	Flunarizine dihydrochloride [30484-77-6]; Down 200; 8.4uM; MCF7; HT_HG-U133A	ZFYVE9 GOLGA1 ARAF RAB11FIP2	2.10e-04	198	34	4	7013_DN
Drug	Fenofibrate [49562-28-9]; Down 200; 11uM; HL60; HT_HG-U133A	ZFYVE9 NFAT5 SS18 SMAD3	2.10e-04	198	34	4	2401_DN
Drug	Griseofulvin [126-07-8]; Down 200; 11.2uM; PC3; HT_HG-U133A	ZFYVE9 SS18 MBNL3 SMAD3	2.14e-04	199	34	4	3664_DN
Drug	Methionine sulfoximine (L) [15985-39-4]; Up 200; 22.2uM; HL60; HT_HG-U133A	MED14 BCL9 OMG SMAD3	2.14e-04	199	34	4	2470_UP
Drug	2-propylpentanoic acid; Down 200; 50uM; MCF7; HT_HG-U133A	ARID1A NFAT5 EP300 SMAD3	2.14e-04	199	34	4	6982_DN
Drug	Disopyramide [3737-09-5]; Up 200; 11.8uM; HL60; HT_HG-U133A	FOXO1 SS18 CREBBP SMAD3	2.14e-04	199	34	4	2408_UP
Drug	Penbutolol sulfate [38363-32-5]; Up 200; 5.8uM; HL60; HT_HG-U133A	FOXO1 UPF1 NFAT5 SMAD3	2.14e-04	199	34	4	2972_UP
Drug	Ramipril [87333-19-5]; Down 200; 9.6uM; HL60; HT_HG-U133A	UPF1 ZFYVE9 SS18 OMG	2.18e-04	200	34	4	6150_DN
Drug	Amodiaquin dihydrochloride dihydrate [6398-98-7]; Up 200; 8.6uM; HL60; HG-U133A	OMG EP300 SS18L1 SMAD3	2.18e-04	200	34	4	1570_UP
Drug	Ifenprodil tartrate [23210-58-4]; Up 200; 8.4uM; MCF7; HT_HG-U133A	TAB1 SS18 CREBBP RAB11FIP2	2.18e-04	200	34	4	7404_UP
Drug	Netilmicin sulfate [56931-57-2]; Up 200; 2.8uM; HL60; HT_HG-U133A	ZFYVE9 CLOCK GOLGA1 SMAD3	2.18e-04	200	34	4	2963_UP
Drug	Lynestrenol [52-76-6]; Down 200; 14uM; PC3; HG-U133A	ARID1A STAG2 EP300 SMAD3	2.18e-04	200	34	4	1953_DN
Drug	CP-944629 [668990-94-1]; Down 200; 10uM; MCF7; HT_HG-U133A	BCL9 NFAT5 SS18 MBNL3	2.18e-04	200	34	4	7544_DN
Drug	oxymatrine	CREBBP SMAD3	3.26e-04	18	34	2	ctd:C037573
Drug	4,4'-DBP	CREBBP EP300	3.64e-04	19	34	2	CID000007034
Drug	Linoleic Acid	FOXO1 CREBBP SMAD3	4.33e-04	99	34	3	ctd:D019787
Drug	glutamin	FOXO1 ARID1A NFAT5 CREBBP EP300	5.71e-04	461	34	5	CID000000738
Drug	Dabcyl	ZFYVE9 EP300	5.85e-04	24	34	2	CID000022650
Drug	AC1ND2OB	FOXO1 CREBBP EP300 ARAF	6.32e-04	265	34	4	CID004568637
Drug	2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine	CLOCK SMAD3	7.42e-04	27	34	2	ctd:C061282
Drug	deamino-NAD	BCL9 NFAT5	7.42e-04	27	34	2	CID000004480
Drug	AC1L1K15	EP300 ARAF SMAD3	7.58e-04	120	34	3	CID000005293
Drug	naringenin	STAG2 ARAF SMAD3	1.09e-03	136	34	3	CID000000932
Drug	AC1L2E0P	MED14 ZFYVE9 CREBBP EP300	1.09e-03	307	34	4	CID000019390
Disease	Carcinoma, Transitional Cell	KMT2C ARID1A CREBBP STAG2 EP300	9.28e-10	41	33	5	C0007138
Disease	Bladder Neoplasm	KMT2C ARID1A CREBBP STAG2 EP300	4.77e-07	140	33	5	C0005695
Disease	Malignant neoplasm of urinary bladder	KMT2C ARID1A CREBBP STAG2 EP300	4.94e-07	141	33	5	C0005684
Disease	Menke-Hennekam syndrome	CREBBP EP300	1.21e-06	2	33	2	cv:C5681632
Disease	Rubinstein-Taybi syndrome (implicated_via_orthology)	CREBBP EP300	1.21e-06	2	33	2	DOID:1933 (implicated_via_orthology)
Disease	Rubinstein-Taybi syndrome	CREBBP EP300	1.21e-06	2	33	2	cv:C0035934
Disease	RUBINSTEIN-TAYBI SYNDROME 1	CREBBP EP300	1.21e-06	2	33	2	C4551859
Disease	RUBINSTEIN-TAYBI SYNDROME 1	CREBBP EP300	1.21e-06	2	33	2	180849
Disease	Rubinstein-Taybi syndrome due to CREBBP mutations	CREBBP EP300	1.21e-06	2	33	2	cv:C4551859
Disease	Rubinstein-Taybi syndrome (is_implicated_in)	CREBBP EP300	1.21e-06	2	33	2	DOID:1933 (is_implicated_in)
Disease	Rubinstein-Taybi Syndrome	CREBBP EP300	1.21e-06	2	33	2	C0035934
Disease	Sezary Syndrome	KMT2C ARID1A CREBBP	3.66e-06	27	33	3	C0036920
Disease	Adenoid Cystic Carcinoma	KMT2C ARID1A CREBBP EP300	4.71e-06	100	33	4	C0010606
Disease	MENTAL RETARDATION, AUTOSOMAL DOMINANT 12	ARID1B ARID1A	1.21e-05	5	33	2	C3281201
Disease	Klatskin's tumor (is_implicated_in)	KMT2C ARID1A	1.21e-05	5	33	2	DOID:4927 (is_implicated_in)
Disease	Neoplasm of uncertain or unknown behavior of breast	ARID1B ARID1A EP300	1.32e-05	41	33	3	C0496956
Disease	Breast adenocarcinoma	ARID1B ARID1A EP300	1.32e-05	41	33	3	C0858252
Disease	Neuroblastoma	ARID1B ARID1A YAP1	2.00e-05	47	33	3	C0027819
Disease	prostate cancer (is_marker_for)	FOXO1 KMT2C EP300 SMAD3	2.73e-05	156	33	4	DOID:10283 (is_marker_for)
Disease	Diffuse Large B-Cell Lymphoma	FOXO1 CREBBP EP300	3.21e-05	55	33	3	C0079744
Disease	Embryonal Rhabdomyosarcoma	ARID1A YAP1	3.38e-05	8	33	2	C0206656
Disease	Endometrial Neoplasms	CHD4 ARID1A EP300	3.77e-05	58	33	3	C0014170
Disease	Leukemia, Myelocytic, Acute	FOXO1 KMT2C CREBBP EP300	4.09e-05	173	33	4	C0023467
Disease	neuroblastoma (is_implicated_in)	ARID1B ARID1A	5.43e-05	10	33	2	DOID:769 (is_implicated_in)
Disease	keratoconus	FOXO1 MAML2 SMAD3	5.56e-05	66	33	3	MONDO_0015486
Disease	alcohol use disorder (implicated_via_orthology)	ARID1B ARID1A CREBBP EP300	6.51e-05	195	33	4	DOID:1574 (implicated_via_orthology)
Disease	Endometrial Carcinoma	CHD4 ARID1A EP300	7.21e-05	72	33	3	C0476089
Disease	Coffin-Siris syndrome	ARID1B ARID1A	9.39e-05	13	33	2	C0265338
Disease	T-Cell Lymphoma	ARID1A EP300	1.44e-04	16	33	2	C0079772
Disease	Squamous cell carcinoma of esophagus	KMT2C CREBBP EP300	1.64e-04	95	33	3	C0279626
Disease	diet measurement, HOMA-B	NFAT5 RAB11FIP2	2.05e-04	19	33	2	EFO_0004469, EFO_0008111
Disease	cancer (implicated_via_orthology)	ARID1B ARID1A YAP1 ARAF	2.21e-04	268	33	4	DOID:162 (implicated_via_orthology)
Disease	Colorectal Neoplasms	ARID1A YAP1 EP300 SMAD3	2.51e-04	277	33	4	C0009404
Disease	Breast Carcinoma	ARID1B ARID1A YAP1 EP300 ARAF	3.08e-04	538	33	5	C0678222
Disease	Intrahepatic Cholangiocarcinoma	KMT2C ARID1A	3.30e-04	24	33	2	C0345905
Disease	Extrahepatic Cholangiocarcinoma	KMT2C ARID1A	3.30e-04	24	33	2	C3805278
Disease	Cholangiocarcinoma	KMT2C ARID1A	3.88e-04	26	33	2	C0206698
Disease	lung non-small cell carcinoma (is_implicated_in)	KMT2C ARID1B ARID1A	5.03e-04	139	33	3	DOID:3908 (is_implicated_in)
Disease	Prostatic Neoplasms	FOXO1 KMT2C CHD7 ARID1A CREBBP	5.71e-04	616	33	5	C0033578
Disease	Malignant neoplasm of prostate	FOXO1 KMT2C CHD7 ARID1A CREBBP	5.71e-04	616	33	5	C0376358
Disease	solar lentigines measurement	TBX18 RAB11FIP2	5.89e-04	32	33	2	EFO_0007850
Disease	autism spectrum disorder (implicated_via_orthology)	ARID1B CHD7 CREBBP	6.53e-04	152	33	3	DOID:0060041 (implicated_via_orthology)
Disease	nasal disorder	FOXO1 SMAD3	7.05e-04	35	33	2	MONDO_0002436
Disease	colorectal cancer (is_marker_for)	CHD4 ARID1A YAP1	7.17e-04	157	33	3	DOID:9256 (is_marker_for)
Disease	diastolic blood pressure, systolic blood pressure	TBX18 ARID1B BCL9 NFAT5 SMAD3	8.33e-04	670	33	5	EFO_0006335, EFO_0006336
Disease	Colorectal Carcinoma	KMT2C ARID1A YAP1 EP300 SMAD3	1.03e-03	702	33	5	C0009402
Disease	nasopharynx carcinoma (is_marker_for)	KMT2C ARID1A	1.06e-03	43	33	2	DOID:9261 (is_marker_for)
Disease	Malignant neoplasm of breast	MED14 ARID1B ARID1A YAP1 EP300 ARAF	1.09e-03	1074	33	6	C0006142

Protein segments in the cluster

Peptide	Gene	Start	Entry
GPTQSTGMMNSPVNQ	EP300	146	Q09472
TTMAPNSLQTSMPGN	AMBN	416	Q9NP70
PRAASPMNHSVQMNS	CREBBP	741	Q92793
PMNHSVQMNSMGSVP	CREBBP	746	Q92793
FPSTMQQHSPMSSQT	AMOTL1	381	Q8IY63
SSEPFMTQGQMPNSS	ARID1B	1361	Q8NFD5
MNTQTMHPSQPQGTY	CHD7	376	Q9P2D1
MQGPQTPQSTSSSMA	ARID1A	1141	O14497
GTSSMSGPQQLMIPQ	KMT2C	3021	Q8NEZ4
GPEMANMAPSVTNNT	GOLGA1	671	Q92805
PNVFNEHMTNSTMSP	KIAA1109	4336	Q2LD37
EHMTNSTMSPGTVGQ	KIAA1109	4341	Q2LD37
PRMTTQSPLNQSSMN	GCN1	711	Q92616
TTSSEQMQPPMFHSQ	NFAT5	1106	O94916
SNQNTMATMASPKQP	NFAT5	1271	O94916
TVNQSPSMMHTQSPG	MED14	1031	O60244
SLSPMTQMLQTQAHP	DCHS2	1096	Q6V1P9
THSMASMPPQRTSNV	MAML2	941	Q8IZL2
SMSQPSQMSQPGLSQ	UPF1	1071	Q92900
PNVHMVSTTAPMDSN	ARAF	216	P10398
TQSSPGTMMQQTPCY	FOXO1	391	Q12778
PTMHQVQSPMLGSPS	BCL9	866	O00512
TLSPMGMTQPLSHSN	BCL9	1076	O00512
GMTQPLSHSNQMPSP	BCL9	1081	O00512
ASNIVPMMHGATPTT	MBNL3	316	Q9NUK0
GHSTLNTMFPPTANM	MBD5	616	Q9P267
NMSEDPSHPSMALNT	CHD4	1806	Q14839
QGHLQSMPTGNMQAS	SPATA31C2	901	B4DYI2
MPSQGQMVNGAHSAS	TAB1	411	Q15750
SITSGMPNNFSEMPQ	OMG	381	P23515
AAGSMVQIPSSMPQN	CLOCK	671	O15516
SMQQTAPNTLPTTSM	SS18L1	131	O75177
HTPVMMQTPQLTSTI	STAG2	1111	Q8N3U4
PQTSLSMQISGMSPQ	TBX18	481	O95935
MNHSMDAGSPNLSPN	SMAD3	196	P84022
SVPSSQSMPVQNQMT	SS18	166	Q15532
TSPPVQQNMMNSASG	YAP1	216	P46937
TQMMVSQIPPNSSNS	USF3	1371	Q68DE3
NIMPSSSFHMSPTSN	RAB11FIP2	416	Q7L804
MMSASSQSPNPNNPA	ZFYVE9	766	O95405