Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionhistone H3K4me/H3K4me2/H3K4me3 demethylase activity

KDM5C KDM5D

2.07e-056242GO:0034647
GeneOntologyMolecularFunctionhistone H3K4 demethylase activity

KDM5C KDM5D

3.86e-058242GO:0032453
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity involved in regulation of cytosolic calcium levels

CACNA1D CACNA1E

4.96e-059242GO:0099511
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels

CACNA1D CACNA1E

4.96e-059242GO:0099626
GeneOntologyMolecularFunctionhigh voltage-gated calcium channel activity

CACNA1D CACNA1E

1.25e-0414242GO:0008331
GeneOntologyMolecularFunctionhistone H3 demethylase activity

KDM5C KDM5D

5.13e-0428242GO:0141052
GeneOntologyMolecularFunctionalpha-actinin binding

CACNA1D PTPRT

6.30e-0431242GO:0051393
GeneOntologyMolecularFunctionhistone demethylase activity

KDM5C KDM5D

6.30e-0431242GO:0032452
GeneOntologyMolecularFunctionprotein demethylase activity

KDM5C KDM5D

6.72e-0432242GO:0140457
GeneOntologyMolecularFunctionactinin binding

CACNA1D PTPRT

1.21e-0343242GO:0042805
GeneOntologyMolecularFunctiondemethylase activity

KDM5C KDM5D

1.27e-0344242GO:0032451
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity

CACNA1D CACNA1E

1.39e-0346242GO:0005245
GeneOntologyMolecularFunction2-oxoglutarate-dependent dioxygenase activity

KDM5C KDM5D

2.75e-0365242GO:0016706
GeneOntologyMolecularFunctiondioxygenase activity

KDM5C KDM5D

6.13e-0398242GO:0051213
GeneOntologyCellularComponentneuronal cell body

DAB2IP BACE1 CACNA1D CACNA1E ASTN2 ERMN

2.89e-04835246GO:0043025
GeneOntologyCellularComponentnuclear body

TOPORS LYRM4 PABPN1 BCLAF1 BCAS2 AHCTF1

4.40e-04903246GO:0016604
GeneOntologyCellularComponentcell body

DAB2IP BACE1 CACNA1D CACNA1E ASTN2 ERMN

5.12e-04929246GO:0044297
GeneOntologyCellularComponentvoltage-gated calcium channel complex

CACNA1D CACNA1E

1.27e-0346242GO:0005891
GeneOntologyCellularComponentnuclear speck

TOPORS PABPN1 BCLAF1 BCAS2

1.37e-03431244GO:0016607
GeneOntologyCellularComponentperikaryon

CACNA1D CACNA1E ASTN2

2.05e-03223243GO:0043204
GeneOntologyCellularComponentsomatodendritic compartment

DAB2IP BACE1 CACNA1D CACNA1E ASTN2 ERMN

2.19e-031228246GO:0036477
GeneOntologyCellularComponentcalcium channel complex

CACNA1D CACNA1E

3.16e-0373242GO:0034704
GeneOntologyCellularComponentciliary transition zone

TOPORS MACIR

3.87e-0381242GO:0035869
MousePhenoabnormal pancreatic alpha cell number

CACNA1D CACNA1E ARX

1.36e-0535193MP:0020577
MousePhenoabnormal pancreatic alpha cell morphology

CACNA1D CACNA1E ARX

3.11e-0546193MP:0005216
DomainLys_sp_deMease-like_dom

KDM5C KDM5D

8.69e-064232IPR013637
DomainPLU-1

KDM5C KDM5D

8.69e-064232PF08429
Domainzf-C5HC2

KDM5C KDM5D

1.45e-055232PF02928
DomainZnf_C5HC2

KDM5C KDM5D

1.45e-055232IPR004198
DomainGPHH_dom

CACNA1D CACNA1E

3.03e-057232IPR031649
DomainVDCC_a1su_IQ

CACNA1D CACNA1E

3.03e-057232IPR014873
DomainCa_chan_IQ

CACNA1D CACNA1E

3.03e-057232SM01062
DomainCa_chan_IQ

CACNA1D CACNA1E

3.03e-057232PF08763
DomainGPHH

CACNA1D CACNA1E

3.03e-057232PF16905
DomainJmjN

KDM5C KDM5D

6.49e-0510232PF02375
DomainJmjN

KDM5C KDM5D

6.49e-0510232SM00545
DomainVDCCAlpha1

CACNA1D CACNA1E

6.49e-0510232IPR002077
DomainJMJN

KDM5C KDM5D

6.49e-0510232PS51183
DomainJmjN

KDM5C KDM5D

6.49e-0510232IPR003349
Domain-

KDM5C KDM5D

1.51e-04152321.10.150.60
DomainARID

KDM5C KDM5D

1.51e-0415232PF01388
DomainBRIGHT

KDM5C KDM5D

1.51e-0415232SM00501
DomainARID_dom

KDM5C KDM5D

1.51e-0415232IPR001606
DomainARID

KDM5C KDM5D

1.51e-0415232PS51011
DomainJmjC

KDM5C KDM5D

3.94e-0424232PF02373
DomainJMJC

KDM5C KDM5D

7.04e-0432232PS51184
DomainJmjC_dom

KDM5C KDM5D

7.04e-0432232IPR003347
DomainJmjC

KDM5C KDM5D

7.48e-0433232SM00558
DomainChannel_four-helix_dom

CACNA1D CACNA1E

2.22e-0357232IPR027359
Domain-

CACNA1D CACNA1E

2.22e-03572321.20.120.350
DomainZinc_finger_PHD-type_CS

KDM5C KDM5D

2.88e-0365232IPR019786
DomainPHD

KDM5C KDM5D

3.81e-0375232PF00628
DomainZnf_PHD-finger

KDM5C KDM5D

4.22e-0379232IPR019787
DomainPHD

KDM5C KDM5D

5.32e-0389232SM00249
DomainZnf_PHD

KDM5C KDM5D

5.56e-0391232IPR001965
DomainZF_PHD_2

KDM5C KDM5D

6.04e-0395232PS50016
DomainZF_PHD_1

KDM5C KDM5D

6.17e-0396232PS01359
DomainIon_trans_dom

CACNA1D CACNA1E

8.59e-03114232IPR005821
DomainIon_trans

CACNA1D CACNA1E

8.59e-03114232PF00520
DomainZnf_FYVE_PHD

KDM5C KDM5D

1.40e-02147232IPR011011
Domain-

TOPORS KDM5C KDM5D

1.71e-024492333.30.40.10
DomainZnf_RING/FYVE/PHD

TOPORS KDM5C KDM5D

1.81e-02459233IPR013083
PathwayKEGG_MEDICUS_REFERENCE_VGCC_CA2_APOPTOTIC_PATHWAY

CACNA1D CACNA1E

3.83e-0423182M47666
PathwayKEGG_MEDICUS_REFERENCE_CA2_ENTRY_VOLTAGE_GATED_CA2_CHANNEL

CACNA1D CACNA1E

4.54e-0425182M47948
PathwayREACTOME_HDMS_DEMETHYLATE_HISTONES

KDM5C KDM5D

6.13e-0429182MM14934
Pubmed

Mutations of histone demethylase genes encoded by X and Y chromosomes, Kdm5c and Kdm5d, lead to noncompaction cardiomyopathy in mice.

KDM5C KDM5D

4.56e-07224232081420
Pubmed

Mouse H-Y encoding Smcy gene and its X chromosomal homolog Smcx.

KDM5C KDM5D

4.56e-07224210441747
Pubmed

Structure and functional characterization of neuronal alpha 1E calcium channel subtypes.

CACNA1D CACNA1E

4.56e-0722428071363
Pubmed

Inefficient purifying selection: the mammalian Y chromosome in the rodent genus Mus.

KDM5C KDM5D

4.56e-07224216416087
Pubmed

Identification of the immunodominant HY H2-D(k) epitope and evaluation of the role of direct and indirect antigen presentation in HY responses.

KDM5D ARX

4.56e-07224216301625
Pubmed

Analysis of mutation rates in the SMCY/SMCX genes shows that mammalian evolution is male driven.

KDM5C KDM5D

4.56e-0722429060413
Pubmed

A mouse Y chromosome gene encoded by a region essential for spermatogenesis and expression of male-specific minor histocompatibility antigens.

KDM5C KDM5D

4.56e-0722427524912
Pubmed

Identification of a mouse male-specific transplantation antigen, H-Y.

KDM5C KDM5D

1.37e-0632427544442
Pubmed

A regulatory path associated with X-linked intellectual disability and epilepsy links KDM5C to the polyalanine expansions in ARX.

KDM5C ARX

1.37e-06324223246292
Pubmed

X- and Y-Linked Chromatin-Modifying Genes as Regulators of Sex-Specific Cancer Incidence and Prognosis.

KDM5C KDM5D

2.74e-06424232732223
Pubmed

A novel X gene with a widely transcribed Y-linked homologue escapes X-inactivation in mouse and human.

KDM5C KDM5D

2.74e-0642427951230
Pubmed

Novel JARID1C/SMCX mutations in patients with X-linked mental retardation.

KDM5C KDM5D

2.74e-06424216541399
Pubmed

The X-linked mental retardation gene SMCX/JARID1C defines a family of histone H3 lysine 4 demethylases.

KDM5C KDM5D

2.74e-06424217320160
Pubmed

Analysis of a Set of KDM5C Regulatory Genes Mutated in Neurodevelopmental Disorders Identifies Temporal Coexpression Brain Signatures.

KDM5C ARX

2.74e-06424234356104
Pubmed

Functional disorders of the sympathetic nervous system in mice lacking the alpha 1B subunit (Cav 2.2) of N-type calcium channels.

CACNA1D CACNA1E

4.56e-06524211296258
Pubmed

Antinociceptive effect of different types of calcium channel inhibitors and the distribution of various calcium channel alpha 1 subunits in the dorsal horn of spinal cord in mice.

CACNA1D CACNA1E

4.56e-06524215451373
Pubmed

Developmental expression patterns of alpha1H T-type Ca2+ channels during spermatogenesis and organogenesis in mice.

CACNA1D CACNA1E

4.56e-06524212060068
Pubmed

Enhanced expression of L-type Cav1.3 calcium channels in murine embryonic hearts from Cav1.2-deficient mice.

CACNA1D CACNA1E

9.56e-06724212900400
Pubmed

Evolutionary insights into T-type Ca2+ channel structure, function, and ion selectivity from the Trichoplax adhaerens homologue.

CACNA1D CACNA1E

1.27e-05824228330839
Pubmed

Reduced polyalanine-expanded Arx mutant protein in developing mouse subpallium alters Lmo1 transcriptional regulation.

KDM5C ARX

1.27e-05824224122442
Pubmed

Histone demethylase KDM5C is a SAHA-sensitive central hub at the crossroads of transcriptional axes involved in multiple neurodevelopmental disorders.

KDM5C ARX

1.64e-05924231691806
Pubmed

Dynamic patterns of histone H3 lysine 4 methyltransferases and demethylases during mouse preimplantation development.

KDM5C KDM5D

3.54e-051324224619213
Pubmed

Sex differences in structure and expression of the sex chromosome genes CHD1Z and CHD1W in zebra finches.

KDM5C KDM5D

3.54e-051324214660691
Pubmed

Nomenclature guidelines for X-linked mental retardation.

KDM5C ARX

3.54e-05132421605216
Pubmed

Differential neuronal targeting of a new and two known calcium channel β4 subunit splice variants correlates with their regulation of gene expression.

CACNA1D CACNA1E

4.77e-051524224453333
Pubmed

Voltage-activated calcium channel expression profiles in mouse brain and cultured hippocampal neurons.

CACNA1D CACNA1E

4.77e-051524220188150
Pubmed

Evolutionary strata on the mouse X chromosome correspond to strata on the human X chromosome.

KDM5C KDM5D

4.77e-051524214762062
Pubmed

Sex differences in sex chromosome gene expression in mouse brain.

KDM5C KDM5D

6.94e-051824212023983
Pubmed

Positioning of five genes (CASK, ARX, SAT, IMAGE cDNAs 248928 and 253949) from the human X chromosome short arm with respect to evolutionary breakpoints on the mouse X chromosome.

KDM5C ARX

1.47e-042624210920247
Pubmed

Transcription factor protein interactomes reveal genetic determinants in heart disease.

TOPORS BCLAF1 AHCTF1 KDM5D

1.69e-0441124435182466
Pubmed

Multiplexed barcoded CRISPR-Cas9 screening enabled by CombiGEM.

KDM5C KDM5D

2.38e-043324226864203
Pubmed

Maternal Transient Receptor Potential Vanilloid 6 (Trpv6) Is Involved In Offspring Bone Development.

CACNA1D CACNA1E

3.16e-043824230786075
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

DAB2IP BCLAF1 KDM5C AHCTF1

3.65e-0450324416964243
Pubmed

Identification of Jmjd3 as an Essential Epigenetic Regulator of Hox Gene Temporal Collinear Activation for Body Axial Patterning in Mice.

KDM5C KDM5D

5.26e-044924234368113
Pubmed

Protein interactome reveals converging molecular pathways among autism disorders.

DAB2IP PABPN1 EGFL7 ARX

5.47e-0456024421653829
CytobandEnsembl 112 genes in cytogenetic band chr9q33

DAB2IP ASTN2

2.37e-03138242chr9q33
CytobandEnsembl 112 genes in cytogenetic band chrXp22

CLDN34 KLHL15

7.53e-03250242chrXp22
GeneFamilyAT-rich interaction domain containing

KDM5C KDM5D

7.66e-0515162418
GeneFamilyPHD finger proteins|Lysine demethylases

KDM5C KDM5D

2.00e-0424162485
GeneFamilyCalcium voltage-gated channel subunits

CACNA1D CACNA1E

2.36e-0426162253
GeneFamilyX-linked mental retardation|Angiotensin receptors

KDM5C ARX

9.85e-0453162103
GeneFamilyPHD finger proteins

KDM5C KDM5D

2.81e-039016288
GeneFamilyFibronectin type III domain containing

ASTN2 PTPRT

8.61e-03160162555
CoexpressionLINDGREN_BLADDER_CANCER_WITH_LOH_IN_CHR9Q

DAB2IP TOPORS ASTN2 KDM5D

3.61e-06116244M8411
CoexpressionGSE14769_20MIN_VS_360MIN_LPS_BMDM_DN

CACNA1D KDM5C MACIR KDM5D

3.10e-05200244M3513
CoexpressionGSE20715_WT_VS_TLR4_KO_24H_OZONE_LUNG_DN

PABPN1 BCLAF1 EGFL7 KDM5D

3.10e-05200244M4354
CoexpressionAtlasDevelopingGonad_e14.5_ epididymis_emap-29141_k-means-cluster#2_top-relative-expression-ranked_1000

DAB2IP TOPORS BCLAF1 KDM5D ARX

1.72e-06184245gudmap_developingGonad_e14.5_ epididymis_1000_k2
CoexpressionAtlasDevelopingGonad_e14.5_ epididymis_emap-29141_top-relative-expression-ranked_1000

DAB2IP TOPORS PABPN1 BCLAF1 KDM5C KDM5D ARX

2.09e-05801247gudmap_developingGonad_e14.5_ epididymis_1000
CoexpressionAtlasdev lower uro neuro_e15.5_PelvicGanglion_Sox10_k-means-cluster#2_top-relative-expression-ranked_1000

CACNA1E ASTN2 PTPRT

1.44e-0491243gudmap_dev lower uro neuro_e15.5_PelvicGanglion_Sox10_k2_1000
ToppCell5'-Adult-LargeIntestine-Epithelial-neuro-epithelial-EECs|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1E ASTN2 ASIC4 ARX

2.02e-06171244dd37e1693a5cfc42e40992d504f92048a8038b52
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Tac2_Tacstd2|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ASTN2 PTPRT ARX

3.51e-05119243e868453c02dcf0e07821886b81ca739887d43c67
ToppCellNS-moderate-d_07-13-Myeloid-Mast_cell|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MACIR EGFL7 ASIC4

7.84e-0515624317c38d3b03fc38cb125cf0d165b2fd694cd88edd
ToppCellE17.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CACNA1D ASTN2 EGFL7

1.01e-041702437fa022471e14ac8a3bc147c793368a4d56a8e591
ToppCelldroplet-Thymus-nan-24m-Lymphocytic-DN_to_DP_transition_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination__)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1E MACIR KDM5D

1.03e-04171243d1e87478d8c0329e662849823f5c7604f20e1b1a
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ASTN2 NAB1 ARX

1.08e-04174243e2243f1e48e3275753a2b3a69d06eefce69a8ded
ToppCellILEUM-inflamed-(1)_T_cell-(1)_CD8_Trm|(1)_T_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

RSRP1 BCLAF1 ASIC4

1.28e-04184243cef3ee2a4a0af961aa3b4c92150d423e841ae8c1
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

RSRP1 BCLAF1 AHCTF1

1.36e-04188243ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellILEUM-non-inflamed-(1)_T_cell-(1)_CD8_Trm|(1)_T_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

RSRP1 BCLAF1 ASIC4

1.38e-041892432c8a2fb76ea002bac554bc1c761ce960b5e116e1
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-6_SST_MTHFD2P6|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ASTN2 PTPRT ARX

1.38e-0418924306c44746fa4f02e6e2b3b635cdf2d8dfef3754d3
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

LYRM4 PABPN1 TDRKH

1.41e-04190243651a1d3ae286e40f9d9f60e438211c6148d24143
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-6_SST_MTHFD2P6|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ASTN2 PTPRT ARX

1.43e-04191243de54dab85db70f847de75b3b6d7667a0e13b9bfb
ToppCellcontrol-Myeloid-Mast_cell|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

MACIR EGFL7 ASIC4

1.43e-04191243afebdc59a1f884ce3f2f5fe040e16b0e95e4e7c5
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-6_SST_MTHFD2P6|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ASTN2 PTPRT ARX

1.43e-041912439c0ee270209b02043393416ecc9a81ddedfbb8b6
ToppCellILEUM-non-inflamed-(1)_CD8_Trm|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

RSRP1 BCLAF1 ASIC4

1.45e-04192243a9f89043c97cd2b0ba165e69ee5681094410af37
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-6_SST_MTHFD2P6|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ASTN2 PTPRT ARX

1.47e-041932438b77625bf3c87d39767fb391d1beaca4ab02342b
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-6_SST_MTHFD2P6|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ASTN2 PTPRT ARX

1.47e-041932432c15186d15545804cc262da9137ab825609d4b2c
ToppCellNeuron-Postmitotic-Inhibitory_Neuron-MGE2|World / Primary Cells by Cluster

PTPRT ASIC4 ARX

1.49e-04194243b42fd64b0fb95434a9e4e6586f31d26114a4074b
ToppCellNeuron-Postmitotic-Inhibitory_Neuron-MGE2-10|World / Primary Cells by Cluster

PTPRT ASIC4 ARX

1.49e-0419424381e7bc6516ab8d02ccd1c76a56a3533b788c27c8
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1D RSRP1 KDM5D

1.52e-041952433e519cffa6144a62b06124642a14c9ff39b76554
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1D RSRP1 KDM5D

1.52e-041952437796ea9247f4c63762f0de8490fed08b9717fa23
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW23|fetalBrain_Zhong_nature / Sample Type, Dataset, Time_group, and Cell type.

ASIC4 KDM5D ERMN

1.61e-04199243f30e9d3d095a1e12d759debe27540aad32861db6
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Mesenchymal-BMP_responsible_cell|10w / Sample Type, Dataset, Time_group, and Cell type.

EGFL7 ARX ERMN

1.63e-042002438433f4d3e26f6706bc7f06597d10b89221ce6437
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW23|organoid_Tanaka_cellReport / Sample Type, Dataset, Time_group, and Cell type.

ASIC4 KDM5D ERMN

1.63e-04200243e16bde12326f0cfc4d03f9307cba0e21ea2389cb
ToppCellMacroglial-Polydendrocytes-PDGFRA---|Macroglial / cells hierarchy compared to all cells using T-Statistic

CACNA1D PTPRT ASIC4

1.63e-042002434fc3de4bff7ed2bf40b38462c4b4e9b87af6a4ca
ToppCellMacroglial-Polydendrocytes-PDGFRA-|Macroglial / cells hierarchy compared to all cells using T-Statistic

CACNA1D PTPRT ASIC4

1.63e-04200243f17b5a54e8f9eba9dcd0808ba4e8d275ac41bce2
ToppCellMacroglial-Polydendrocytes-PDGFRA--|Macroglial / cells hierarchy compared to all cells using T-Statistic

CACNA1D PTPRT ASIC4

1.63e-04200243cc3409518f8b436ea92deb955e81114b3f410ff7
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW26-Neuronal-GABAergic_neurons|GW26 / Sample Type, Dataset, Time_group, and Cell type.

CACNA1E PTPRT ARX

1.63e-04200243bad32a95b759fad509401b07bc96a56687c2a592
ToppCellMacroglial-Polydendrocytes-PDGFRA----L1-6|Macroglial / cells hierarchy compared to all cells using T-Statistic

CACNA1D PTPRT ASIC4

1.63e-04200243310cd53db1c137f6af74e6ae682221d7ac27310c
ToppCellMacroglial-Polydendrocytes-PDGFRA|Macroglial / cells hierarchy compared to all cells using T-Statistic

CACNA1D PTPRT ASIC4

1.63e-04200243c24a3099e3d96d8b72f6d05286bb355d661a0377
ToppCellMacroglial-Polydendrocytes|Macroglial / cells hierarchy compared to all cells using T-Statistic

CACNA1D PTPRT ASIC4

1.63e-04200243961858738ce35db8760c8c2e136f8369bc444ccf
Drug1,3-di-o-tolylguanidine

BACE1 CACNA1E BCLAF1 KDM5D

4.76e-0761244CID000007333
Diseasesyndromic X-linked intellectual disability Claes-Jensen type (implicated_via_orthology)

KDM5C KDM5D

3.48e-064232DOID:0060809 (implicated_via_orthology)
DiseasePARTINGTON X-LINKED MENTAL RETARDATION SYNDROME

KDM5C ARX

1.62e-058232C0796250
Diseasesyndromic intellectual disability (implicated_via_orthology)

KDM5C KDM5D

6.93e-0516232DOID:0050888 (implicated_via_orthology)
Diseasetriacylglycerol 56:7 measurement

PTPRT AHCTF1

2.33e-0429232EFO_0010434
Diseasetriacylglycerol 58:8 measurement

PTPRT AHCTF1

3.40e-0435232EFO_0010442
Diseasetriacylglycerol 56:6 measurement

PTPRT AHCTF1

5.15e-0443232EFO_0010433
Diseaseresponse to hydrochlorothiazide, triglyceride measurement

DAB2IP MACIR

6.15e-0447232EFO_0004530, EFO_0005202
Diseaseautism

BCAS2 KDM5D

6.41e-0448232EFO_0003758
Diseaseschizophrenia (implicated_via_orthology)

BACE1 CACNA1D

1.28e-0368232DOID:5419 (implicated_via_orthology)
Diseaseintellectual disability (implicated_via_orthology)

KDM5C KDM5D

1.56e-0375232DOID:1059 (implicated_via_orthology)
DiseaseDystonia

CACNA1E ARX

2.04e-0386232C0013421
Diseaseglutamine measurement

ASTN2 NAB1

2.59e-0397232EFO_0009768
Diseaseverbal-numerical reasoning measurement

CACNA1E MACIR

4.66e-03131232EFO_0008394
DiseaseGlobal developmental delay

CACNA1E KDM5C

4.79e-03133232C0557874

Protein segments in the cluster

PeptideGeneStartEntry
RYYQRQLSSTYRDLR

BACE1

111

P56817
ACSTYRTIYRTAYRR

EGFL7

61

Q9UHF1
TYKSRRRSYHSSLRL

CACNA1E

2046

Q15878
LTFYTEQYRSRRRSK

ASTN2

411

O75129
SARKSTGRSSYYYRL

DAB2IP

6

Q5VWQ8
ARQISREVTYKYTYR

NAB1

301

Q13506
SSSRQYLRYRYTLDE

KDM5D

731

Q9BY66
ARSSRLYKTRSRYYQ

MACIR

101

Q96GV9
RYLARKYNRNETYIR

ASIC4

396

Q96FT7
SRNAYSRYNTISYRK

ERMN

251

Q8TAM6
LTIKRRRNAYSYSYY

PTPRT

766

O14522
YRARTTNYNSSRSRF

PABPN1

266

Q86U42
VKTSEFYRYSRQLRY

KLHL15

236

Q96M94
KKRYSSRSRSRTYSR

BCLAF1

31

Q9NYF8
KRFSAYNYRTYAVRR

LYRM4

21

Q9HD34
RKQRRYRTTFTSYQL

ARX

326

Q96QS3
NYYTSRRQKFERLSR

AHCTF1

701

Q8WYP5
QRRSSVKRTRYYETY

CACNA1D

1796

Q01668
VKRTRYYETYIRSDS

CACNA1D

1801

Q01668
RRYRPTKNYLSYLTA

BCAS2

41

O75934
QRKYRRYSRSYSRSR

RSRP1

71

Q9BUV0
RRRTNSTTTKFCYRY

CLDN34

61

H7C241
SATVAYILYRRYRES

TDRKH

26

Q9Y2W6
YESSYRRRTLSRAHY

TOPORS

716

Q9NS56
SSSRQYLRYRYTLDE

KDM5C

741

P41229