Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	actin binding	WIPF1 MAP1B SYNE1 MTSS1 GBP2 LMOD3 CCDC88A ANLN FRG1 SYNE2 DIAPH3 MLPH IQGAP3 MYO16	5.22e-08	479	94	14	GO:0003779
GeneOntologyMolecularFunction	cytoskeletal protein binding	WIPF1 MAP1B CLIP2 SYNE1 MTSS1 GBP2 KIF20B LMOD3 CCDC88A LLGL2 ANLN FRG1 SYNE2 RP1 DIAPH3 MLPH IQGAP3 MYO16 SMAD2	7.11e-07	1099	94	19	GO:0008092
GeneOntologyMolecularFunction	ATP hydrolysis activity	DNAH3 ABCC5 CHD9 MCM4 RFC1 DDX55 KIF20B IQCA1L CHD6 ATP2B1	4.31e-05	441	94	10	GO:0016887
GeneOntologyMolecularFunction	ATP-dependent activity	DNAH3 ABCC5 CHD9 MCM4 RFC1 DDX55 KIF20B IQCA1L CHD6 ATP2B1 TOP2B	1.45e-04	614	94	11	GO:0140657
GeneOntologyMolecularFunction	H3K27me3 modified histone binding	TAF1 TAF1L	2.17e-04	5	94	2	GO:0061628
GeneOntologyMolecularFunction	cytoskeleton-nuclear membrane anchor activity	SYNE1 SYNE2	2.17e-04	5	94	2	GO:0140444
GeneOntologyMolecularFunction	basal RNA polymerase II transcription machinery binding	GTF2F1 RPRD2 TAF1 TAF1L	2.65e-04	66	94	4	GO:0001099
GeneOntologyMolecularFunction	basal transcription machinery binding	GTF2F1 RPRD2 TAF1 TAF1L	2.65e-04	66	94	4	GO:0001098
GeneOntologyMolecularFunction	RNA polymerase II general transcription initiation factor binding	GTF2F1 TAF1 TAF1L	2.72e-04	27	94	3	GO:0001091
GeneOntologyMolecularFunction	ATP-dependent activity, acting on DNA	CHD9 MCM4 RFC1 CHD6 TOP2B	3.36e-04	127	94	5	GO:0008094
GeneOntologyMolecularFunction	microtubule binding	MAP1B CLIP2 KIF20B CCDC88A RP1 DIAPH3 MLPH	6.32e-04	308	94	7	GO:0008017
GeneOntologyMolecularFunction	promoter-specific chromatin binding	GTF2F1 TAF1 TAF1L SMAD3	6.37e-04	83	94	4	GO:1990841
GeneOntologyMolecularFunction	nucleoside-triphosphatase regulator activity	DOCK8 SIPA1L3 GBP2 BCR ARHGAP6 CCDC88A LLGL2 IQGAP3 PLCE1	6.42e-04	507	94	9	GO:0060589
GeneOntologyMolecularFunction	GTPase regulator activity	DOCK8 SIPA1L3 GBP2 BCR ARHGAP6 CCDC88A LLGL2 IQGAP3 PLCE1	6.42e-04	507	94	9	GO:0030695
GeneOntologyMolecularFunction	RNA polymerase I general transcription initiation factor activity	TAF1 TAF1L	7.73e-04	9	94	2	GO:0001181
GeneOntologyMolecularFunction	protein domain specific binding	WIPF1 ADGRB1 RFC1 KIF20B ARHGAP6 ZNF106 GTF2F1 CCDC88A LLGL2 AP2A2 ATP2B1 SMAD2	8.15e-04	875	94	12	GO:0019904
GeneOntologyMolecularFunction	ribonucleoside triphosphate phosphatase activity	DNAH3 ABCC5 GBP2 CHD9 MCM4 RFC1 DDX55 KIF20B IQCA1L CHD6 ATP2B1	1.03e-03	775	94	11	GO:0017111
GeneOntologyMolecularFunction	co-SMAD binding	SMAD2 SMAD3	1.40e-03	12	94	2	GO:0070410
GeneOntologyMolecularFunction	RNA polymerase II general transcription initiation factor activity	GTF2F1 TAF1 TAF1L	1.89e-03	52	94	3	GO:0016251
GeneOntologyMolecularFunction	pyrophosphatase activity	DNAH3 ABCC5 GBP2 CHD9 MCM4 RFC1 DDX55 KIF20B IQCA1L CHD6 ATP2B1	1.94e-03	839	94	11	GO:0016462
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides	DNAH3 ABCC5 GBP2 CHD9 MCM4 RFC1 DDX55 KIF20B IQCA1L CHD6 ATP2B1	1.96e-03	840	94	11	GO:0016817
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	DNAH3 ABCC5 GBP2 CHD9 MCM4 RFC1 DDX55 KIF20B IQCA1L CHD6 ATP2B1	1.96e-03	840	94	11	GO:0016818
GeneOntologyMolecularFunction	I-SMAD binding	SMAD2 SMAD3	2.85e-03	17	94	2	GO:0070411
GeneOntologyBiologicalProcess	actin filament-based process	WIPF1 DSP MTSS1 ADGRB1 BCR LMOD3 ARHGAP6 CCDC88A LLGL2 ANLN SYNE2 AKAP11 DIAPH3 IQGAP3 NCK2 SMAD3	3.37e-06	912	94	16	GO:0030029
GeneOntologyBiologicalProcess	actin cytoskeleton organization	WIPF1 MTSS1 ADGRB1 BCR LMOD3 ARHGAP6 CCDC88A LLGL2 ANLN AKAP11 DIAPH3 IQGAP3 NCK2 SMAD3	1.59e-05	803	94	14	GO:0030036
GeneOntologyBiologicalProcess	cortical actin cytoskeleton organization	LLGL2 ANLN AKAP11 IQGAP3	5.22e-05	45	94	4	GO:0030866
GeneOntologyBiologicalProcess	plasma membrane bounded cell projection assembly	INTU SYNE1 CNTRL MTSS1 CC2D2B CCDC88A ANLN SYNE2 RP1 NCK2 PLCE1 BBOF1	5.24e-05	670	94	12	GO:0120031
GeneOntologyBiologicalProcess	cell projection assembly	INTU SYNE1 CNTRL MTSS1 CC2D2B CCDC88A ANLN SYNE2 RP1 NCK2 PLCE1 BBOF1	6.47e-05	685	94	12	GO:0030031
GeneOntologyBiologicalProcess	positive regulation of cellular component biogenesis	SLF1 MAP1B MTSS1 ADGRB1 GBP2 CCDC88A ANLN RP1 NCK2 SMAD3 PLCE1	6.82e-05	582	94	11	GO:0044089
GeneOntologyBiologicalProcess	regulation of cellular component biogenesis	INTU SLF1 MAP1B SYNE1 MTSS1 ADGRB1 GBP2 LMOD3 ARHGAP6 CCDC88A ANLN SYNE2 RP1 NCK2 SMAD3 PLCE1	8.73e-05	1189	94	16	GO:0044087
GeneOntologyBiologicalProcess	regulation of organelle organization	INTU SLF1 MAP1B SYNE1 MTSS1 KIF20B MAP3K4 LMOD3 ARHGAP6 CCDC88A ATG12 SYNE2 MEIOSIN RP1 DIAPH3 NCK2 SMAD3	1.07e-04	1342	94	17	GO:0033043
GeneOntologyBiologicalProcess	cortical cytoskeleton organization	LLGL2 ANLN AKAP11 IQGAP3	1.33e-04	57	94	4	GO:0030865
GeneOntologyBiologicalProcess	regulation of cilium assembly	INTU SYNE1 CCDC88A SYNE2 RP1	1.36e-04	108	94	5	GO:1902017
GeneOntologyBiologicalProcess	regulation of plasma membrane bounded cell projection assembly	INTU SYNE1 CCDC88A ANLN SYNE2 RP1 PLCE1	1.40e-04	248	94	7	GO:0120032
GeneOntologyBiologicalProcess	regulation of cell projection assembly	INTU SYNE1 CCDC88A ANLN SYNE2 RP1 PLCE1	1.51e-04	251	94	7	GO:0060491
GeneOntologyBiologicalProcess	establishment of cell polarity	MAP1B DOCK8 SIPA1L3 KIF20B LLGL2 DIAPH3	1.60e-04	177	94	6	GO:0030010
GeneOntologyBiologicalProcess	regulation of supramolecular fiber organization	MAP1B MTSS1 LMOD3 ARHGAP6 CCDC88A RP1 DIAPH3 NCK2 SMAD3	1.75e-04	438	94	9	GO:1902903
GeneOntologyBiologicalProcess	microtubule-based process	DNAH3 INTU MAP1B CLIP2 CNTRL KIF20B IQCA1L CCDC88A LLGL2 SYNE2 VPS13A RP1 DIAPH3 BBOF1	3.01e-04	1058	94	14	GO:0007017
GeneOntologyBiologicalProcess	regulation of establishment or maintenance of cell polarity	DOCK8 KIF20B LLGL2	3.40e-04	30	94	3	GO:0032878
GeneOntologyCellularComponent	actin cytoskeleton	WIPF1 SIPA1L3 MTSS1 GBP2 LMOD3 ARHGAP6 LLGL2 ANLN DIAPH3 MLPH MYO16	3.30e-05	576	89	11	GO:0015629
GeneOntologyCellularComponent	perinuclear region of cytoplasm	SH3RF1 MAP1B HECTD3 SYNE1 CNTRL ADGRB1 ABCC5 GBP2 KIF20B MAP3K4 GSDMA MLPH MYO16	1.57e-04	934	89	13	GO:0048471
GeneOntologyCellularComponent	heteromeric SMAD protein complex	SMAD2 SMAD3	4.94e-04	8	89	2	GO:0071144
GeneOntologyCellularComponent	microtubule associated complex	DNAH3 MAP1B CLIP2 KIF20B RP1	6.28e-04	161	89	5	GO:0005875
GeneOntologyCellularComponent	SMAD protein complex	SMAD2 SMAD3	7.89e-04	10	89	2	GO:0071141
GeneOntologyCellularComponent	microtubule organizing center attachment site	SYNE1 SYNE2	9.62e-04	11	89	2	GO:0034992
GeneOntologyCellularComponent	meiotic nuclear membrane microtubule tethering complex	SYNE1 SYNE2	9.62e-04	11	89	2	GO:0034993
GeneOntologyCellularComponent	nuclear membrane protein complex	SYNE1 SYNE2	9.62e-04	11	89	2	GO:0106083
GeneOntologyCellularComponent	nuclear membrane microtubule tethering complex	SYNE1 SYNE2	9.62e-04	11	89	2	GO:0106094
GeneOntologyCellularComponent	transcription factor TFIID complex	GTF2F1 TAF1 TAF1L	1.06e-03	47	89	3	GO:0005669
GeneOntologyCellularComponent	cell leading edge	SH3RF1 WIPF1 DOCK8 MTSS1 CCDC88A SYNE2 ATP2B1 PLCE1	1.31e-03	500	89	8	GO:0031252
GeneOntologyCellularComponent	supramolecular fiber	DNAH3 WIPF1 MAP1B CLIP2 DSP SYNE1 KIF20B LMOD3 ARHGAP6 FRG1 SYNE2 RP1 DIAPH3	1.41e-03	1179	89	13	GO:0099512
GeneOntologyCellularComponent	supramolecular polymer	DNAH3 WIPF1 MAP1B CLIP2 DSP SYNE1 KIF20B LMOD3 ARHGAP6 FRG1 SYNE2 RP1 DIAPH3	1.50e-03	1187	89	13	GO:0099081
GeneOntologyCellularComponent	contractile ring	KIF20B ANLN	1.58e-03	14	89	2	GO:0070938
HumanPheno	Cardiac arrest	WIPF1 CLIP2 DSP SYNE1 SYNE2 SMAD2 SMAD3	2.81e-05	159	30	7	HP:0001695
HumanPheno	Pectus excavatum	CLIP2 SYNE1 LMOD3 FRG1 SYNE2 TAF1 ATP2B1 SMAD2 SMAD3	6.46e-05	323	30	9	HP:0000767
HumanPheno	Sudden death	WIPF1 CLIP2 DSP SYNE1 SYNE2 SMAD3	9.22e-05	131	30	6	HP:0001699
HumanPheno	Square-wave jerks	SYNE1 VPS13A	1.00e-04	3	30	2	HP:0025402
HumanPheno	Saccadic intrusion	SYNE1 VPS13A	1.00e-04	3	30	2	HP:0032114
HumanPheno	Aplasia/Hypoplasia of the skin	MAP1B DSP NSD2 CHD6 TAF1 SMAD2 SMAD3	1.26e-04	201	30	7	HP:0008065
MousePheno	enlarged stomach	ANKRD20A3P ANKRD20A8P ANKRD18B ANKRD20A4P ANKRD20A1	6.68e-07	33	72	5	MP:0003883
MousePheno	abnormal sternum morphology	INTU ANKRD20A3P ANKRD20A8P ANKRD18B MAP3K4 ANKRD20A4P ANKRD20A1 SMAD3	4.80e-05	255	72	8	MP:0000157
MousePheno	disorganized cortical plate	KIF20B TOP2B	7.82e-05	3	72	2	MP:0008442
MousePheno	abnormal digestive system morphology	WIPF1 HECTD3 DSP NSD2 GBP2 MCM4 ANKRD20A3P ANKRD20A8P BCR KIF20B ANKRD18B NLRP9 ANKRD20A4P ANKRD20A1 TOP2B SMAD2 SMAD3	1.34e-04	1233	72	17	MP:0000462
MousePheno	abnormal pectoral girdle bone morphology	INTU ANKRD20A3P ANKRD20A8P ANKRD18B MAP3K4 ANKRD20A4P ANKRD20A1 SMAD3	1.52e-04	301	72	8	MP:0004508
MousePheno	absent subplate	MAP1B TOP2B	1.56e-04	4	72	2	MP:0008443
Domain	TAF_II_230-bd	TAF1 TAF1L	2.35e-05	2	91	2	IPR009067
Domain	TFIID_sub1_DUF3591	TAF1 TAF1L	2.35e-05	2	91	2	IPR022591
Domain	-	TAF1 TAF1L	2.35e-05	2	91	2	1.10.1100.10
Domain	TBP-binding	TAF1 TAF1L	2.35e-05	2	91	2	PF09247
Domain	DUF3591	TAF1 TAF1L	2.35e-05	2	91	2	PF12157
Domain	TAF1_animal	TAF1 TAF1L	2.35e-05	2	91	2	IPR011177
Domain	WH2	WIPF1 MTSS1 LMOD3	5.98e-05	16	91	3	PF02205
Domain	AHD	RTKN2 ANLN	7.02e-05	3	91	2	IPR012966
Domain	Anillin	RTKN2 ANLN	7.02e-05	3	91	2	PF08174
Domain	WH2_dom	WIPF1 MTSS1 LMOD3	1.40e-04	21	91	3	IPR003124
Domain	KASH	SYNE1 SYNE2	1.40e-04	4	91	2	PF10541
Domain	KASH	SYNE1 SYNE2	1.40e-04	4	91	2	IPR012315
Domain	KASH	SYNE1 SYNE2	1.40e-04	4	91	2	PS51049
Domain	KASH	SYNE1 SYNE2	1.40e-04	4	91	2	SM01249
Domain	WH2	WIPF1 MTSS1 LMOD3	2.10e-04	24	91	3	PS51082
Domain	tRNA-bd_arm	DSP KIF20B RPRD2	2.10e-04	24	91	3	IPR010978
Domain	BRK	CHD9 CHD6	3.48e-04	6	91	2	SM00592
Domain	BRK_domain	CHD9 CHD6	3.48e-04	6	91	2	IPR006576
Domain	BRK	CHD9 CHD6	3.48e-04	6	91	2	PF07533
Domain	Spectrin_repeat	DSP SYNE1 SYNE2	3.73e-04	29	91	3	IPR002017
Domain	C2	BCR C2CD2 FER1L6 PLCL2 PLCE1	4.51e-04	131	91	5	PF00168
Domain	Spectrin/alpha-actinin	DSP SYNE1 SYNE2	5.01e-04	32	91	3	IPR018159
Domain	SPEC	DSP SYNE1 SYNE2	5.01e-04	32	91	3	SM00150
Domain	C2	BCR C2CD2 FER1L6 PLCL2 PLCE1	5.54e-04	137	91	5	SM00239
Domain	Ank_2	SLF1 ANKRD20A2P ANKRD20A3P ANKRD20A4P MYO16 ANKRD20A1	6.41e-04	215	91	6	PF12796
Domain	Dwarfin	SMAD2 SMAD3	6.45e-04	8	91	2	IPR013790
Domain	DWB	SMAD2 SMAD3	6.45e-04	8	91	2	SM00524
Domain	MH2	SMAD2 SMAD3	6.45e-04	8	91	2	PS51076
Domain	MH1	SMAD2 SMAD3	6.45e-04	8	91	2	PS51075
Domain	-	SMAD2 SMAD3	6.45e-04	8	91	2	3.90.520.10
Domain	MAD_homology_MH1	SMAD2 SMAD3	6.45e-04	8	91	2	IPR013019
Domain	MH2	SMAD2 SMAD3	6.45e-04	8	91	2	PF03166
Domain	SMAD_dom_Dwarfin-type	SMAD2 SMAD3	6.45e-04	8	91	2	IPR001132
Domain	C2	BCR C2CD2 FER1L6 PLCL2 PLCE1	6.52e-04	142	91	5	PS50004
Domain	-	BCR C2CD2 FER1L6 PLCL2 PLCE1	7.86e-04	148	91	5	2.60.40.150
Domain	Clathrin_a/b/g-adaptin_app_Ig	GGA3 AP2A2	8.27e-04	9	91	2	IPR008152
Domain	Alpha_adaptinC2	GGA3 AP2A2	8.27e-04	9	91	2	PF02883
Domain	Alpha_adaptinC2	GGA3 AP2A2	8.27e-04	9	91	2	SM00809
Domain	P-loop_NTPase	DNAH3 ABCC5 GBP2 CHD9 MCM4 RFC1 DDX55 KIF20B NLRP9 LRRIQ1 CHD6 MYO16	8.27e-04	848	91	12	IPR027417
Domain	Ank	SLF1 ANKRD20A2P ANKRD20A3P ANKRD20A4P MYO16 ANKRD20A1	8.71e-04	228	91	6	PF00023
Domain	6PGD_dom_2	HIBADH HADH	1.03e-03	10	91	2	IPR013328
Domain	-	HIBADH HADH	1.03e-03	10	91	2	1.10.1040.10
Domain	C2_dom	BCR C2CD2 FER1L6 PLCL2 PLCE1	1.24e-03	164	91	5	IPR000008
Domain	-	SLF1 ANKRD20A2P ANKRD20A3P ANKRD20A4P MYO16 ANKRD20A1	1.34e-03	248	91	6	1.25.40.20
Domain	ANK	SLF1 ANKRD20A2P ANKRD20A3P ANKRD20A4P MYO16 ANKRD20A1	1.43e-03	251	91	6	SM00248
Domain	ANK_REPEAT	SLF1 ANKRD20A2P ANKRD20A3P ANKRD20A4P MYO16 ANKRD20A1	1.49e-03	253	91	6	PS50088
Domain	MAD_homology1_Dwarfin-type	SMAD2 SMAD3	1.50e-03	12	91	2	IPR003619
Domain	DWA	SMAD2 SMAD3	1.50e-03	12	91	2	SM00523
Domain	Coatomer/clathrin_app_Ig-like	GGA3 AP2A2	1.50e-03	12	91	2	IPR013041
Domain	MH1	SMAD2 SMAD3	1.50e-03	12	91	2	PF03165
Domain	Ankyrin_rpt-contain_dom	SLF1 ANKRD20A2P ANKRD20A3P ANKRD20A4P MYO16 ANKRD20A1	1.52e-03	254	91	6	IPR020683
Domain	ANK_REP_REGION	SLF1 ANKRD20A2P ANKRD20A3P ANKRD20A4P MYO16 ANKRD20A1	1.52e-03	254	91	6	PS50297
Domain	Ankyrin_rpt	SLF1 ANKRD20A2P ANKRD20A3P ANKRD20A4P MYO16 ANKRD20A1	1.77e-03	262	91	6	IPR002110
Domain	WH2	WIPF1 MTSS1	2.06e-03	14	91	2	SM00246
Domain	HMG_BOX_2	NSD2 MEIOSIN TAF1	2.32e-03	54	91	3	PS50118
Domain	PLipase_C_Pinositol-sp_Y	PLCL2 PLCE1	2.37e-03	15	91	2	IPR001711
Domain	EF-hand_like	PLCL2 PLCE1	2.37e-03	15	91	2	PF09279
Domain	PIPLC_Y_DOMAIN	PLCL2 PLCE1	2.37e-03	15	91	2	PS50008
Domain	PI-PLC_fam	PLCL2 PLCE1	2.37e-03	15	91	2	IPR001192
Domain	PLC_EF-hand-like	PLCL2 PLCE1	2.37e-03	15	91	2	IPR015359
Domain	PI-PLC-Y	PLCL2 PLCE1	2.37e-03	15	91	2	PF00387
Domain	PLCYc	PLCL2 PLCE1	2.37e-03	15	91	2	SM00149
Domain	SMAD_dom-like	SMAD2 SMAD3	2.70e-03	16	91	2	IPR017855
Domain	-	SMAD2 SMAD3	2.70e-03	16	91	2	2.60.200.10
Domain	PI-PLC-X	PLCL2 PLCE1	3.41e-03	18	91	2	PF00388
Domain	PLCXc	PLCL2 PLCE1	3.41e-03	18	91	2	SM00148
Domain	PIPLC_X_DOMAIN	PLCL2 PLCE1	3.80e-03	19	91	2	PS50007
Domain	PLipase_C_PInositol-sp_X_dom	PLCL2 PLCE1	3.80e-03	19	91	2	IPR000909
Domain	6-PGluconate_DH_C-like	HIBADH HADH	3.80e-03	19	91	2	IPR008927
Domain	CH	SYNE1 SYNE2 IQGAP3	3.93e-03	65	91	3	SM00033
Domain	CH	SYNE1 SYNE2 IQGAP3	4.84e-03	70	91	3	PF00307
Pathway	REACTOME_RHO_GTPASE_CYCLE	SH3RF1 WIPF1 DSP DOCK8 BCR ARHGAP6 CCDC88A ANLN DIAPH3 IQGAP3 NCK2	9.21e-06	450	68	11	M27078
Pathway	REACTOME_RHO_GTPASE_CYCLE	SH3RF1 DSP DOCK8 BCR ARHGAP6 CCDC88A ANLN DIAPH3 IQGAP3 NCK2	4.47e-05	439	68	10	MM15595
Pathway	WP_ENVELOPE_PROTEINS_AND_THEIR_POTENTIAL_ROLES_IN_EDMD_PHYSIOPATHOLOGY	SYNE1 SYNE2 SMAD2 SMAD3	6.94e-05	46	68	4	M39828
Pathway	REACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3	SH3RF1 WIPF1 DSP DOCK8 BCR ARHGAP6 CCDC88A ANLN DIAPH3 IQGAP3 NCK2	2.53e-04	649	68	11	MM15690
Pathway	REACTOME_RHOB_GTPASE_CYCLE	BCR ANLN DIAPH3 IQGAP3	3.38e-04	69	68	4	MM15596
Pathway	REACTOME_SIGNALING_BY_NODAL	SMAD2 SMAD3	3.40e-04	6	68	2	MM14517
Pathway	REACTOME_RHOB_GTPASE_CYCLE	BCR ANLN DIAPH3 IQGAP3	3.57e-04	70	68	4	M41806
Pathway	REACTOME_RHOC_GTPASE_CYCLE	BCR ANLN DIAPH3 IQGAP3	3.57e-04	70	68	4	MM15597
Pathway	REACTOME_TRANSCRIPTION_OF_THE_HIV_GENOME	ELOA GTF2F1 TAF1 TAF1L	3.57e-04	70	68	4	M27008
Pathway	REACTOME_RHOC_GTPASE_CYCLE	BCR ANLN DIAPH3 IQGAP3	4.42e-04	74	68	4	M41807
Pathway	REACTOME_LOSS_OF_FUNCTION_OF_SMAD2_3_IN_CANCER	SMAD2 SMAD3	4.74e-04	7	68	2	M29623
Pathway	REACTOME_FOXO_MEDIATED_TRANSCRIPTION_OF_CELL_CYCLE_GENES	SMAD2 SMAD3	4.74e-04	7	68	2	MM15661
Pathway	REACTOME_RHOA_GTPASE_CYCLE	BCR ARHGAP6 ANLN DIAPH3 IQGAP3	6.05e-04	142	68	5	MM15576
Pathway	REACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3	SH3RF1 WIPF1 DSP DOCK8 BCR ARHGAP6 CCDC88A ANLN DIAPH3 IQGAP3 NCK2	6.10e-04	720	68	11	M41838
Pathway	REACTOME_RNA_POLYMERASE_II_PRE_TRANSCRIPTION_EVENTS	ELOA GTF2F1 TAF1 TAF1L	6.23e-04	81	68	4	M865
Pathway	KEGG_BASAL_TRANSCRIPTION_FACTORS	GTF2F1 TAF1 TAF1L	6.29e-04	35	68	3	M4864
Pathway	KEGG_MEDICUS_REFERENCE_TGF_BETA_SIGNALING_PATHWAY	SMAD2 SMAD3	6.30e-04	8	68	2	M47415
Pathway	KEGG_MEDICUS_REFERENCE_NODAL_SIGNALING_PATHWAY	SMAD2 SMAD3	6.30e-04	8	68	2	M47849
Pathway	KEGG_MEDICUS_REFERENCE_ACTIVIN_SIGNALING_PATHWAY	SMAD2 SMAD3	6.30e-04	8	68	2	M47846
Pathway	REACTOME_SIGNALING_BY_TGF_BETA_RECEPTOR_COMPLEX_IN_CANCER	SMAD2 SMAD3	6.30e-04	8	68	2	M27246
Pathway	REACTOME_RNA_POLYMERASE_II_PRE_TRANSCRIPTION_EVENTS	ELOA GTF2F1 TAF1 TAF1L	6.83e-04	83	68	4	MM15314
Pathway	REACTOME_RHOA_GTPASE_CYCLE	BCR ARHGAP6 ANLN DIAPH3 IQGAP3	7.53e-04	149	68	5	M41805
Pathway	REACTOME_CDC42_GTPASE_CYCLE	WIPF1 DOCK8 BCR DIAPH3 IQGAP3	8.99e-04	155	68	5	M41808
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	ELOA INTU MAP1B DSP NSD2 SYNE1 SIPA1L3 CNTRL ABCC5 FAM98B DDX55 FER1L6 LMOD3 AP2A2 SYNE2 VPS13A BOD1L1 CHD6 DIAPH3 MLPH ATP2B1 RPL7A TOP2B CAVIN2 BBOF1	1.29e-13	1442	97	25	35575683
Pubmed	Expression of testicular germ cell genes identified by differential display analysis.	ANKRD20A3P ANKRD20A8P ANKRD18B ANKRD20A4P ANKRD20A1	8.46e-12	8	97	5	12634303
Pubmed	A human MAP kinase interactome.	SH3RF1 WIPF1 CLIP2 DSP SYNE1 CNTRL MAP3K4 ZNF106 RTKN2 CCDC88A CHD6 TAF1 ZNF839 RPL7A	8.73e-11	486	97	14	20936779
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	ELOA SLF1 MAP1B DSP NSD2 MCM4 FAM98B RFC1 KIF20B EMSY ANLN PUM3 RPRD2 BOD1L1 TAF1 TAF1L TOP2B	1.18e-09	954	97	17	36373674
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	ELOA NSD2 CHD9 RFC1 DDX55 KIF20B EMSY ANLN FRG1 PUM3 BOD1L1 CHD6 TAF1 TOP2B	1.59e-09	608	97	14	36089195
Pubmed	Nucleolar proteome dynamics.	ELOA MCM4 RFC1 DDX55 ZNF106 GTF2F1 ANLN FRG1 PUM3 RPL7A TOP2B	2.68e-08	419	97	11	15635413
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	SH3RF1 MAP1B DSP SIPA1L3 BCR ZNF106 CCDC88A MAST4 ANLN SYNE2 OTUD7A AKAP11 BOD1L1 ATP2B1	1.22e-07	861	97	14	36931259
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	WIPF1 DSP SYNE1 ATG12 SYNE2 PUM3 MRTO4 TAF1 SMAD2 SMAD3 PLCE1	1.50e-07	497	97	11	23414517
Pubmed	Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.	ELOA CHD9 EMSY ZNF106 GTF2F1 AP2A2 RPRD2 IQGAP3	2.16e-07	222	97	8	37071664
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	CLIP2 SYNE1 SIPA1L3 AP2A2 SYNE2 AKAP11 RPRD2 CHD6	2.39e-07	225	97	8	12168954
Pubmed	DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.	SLF1 FAM98B KIF20B EMSY ZNF106 ANLN RPRD2 BOD1L1 ATP2B1 CAVIN2	5.83e-07	453	97	10	29656893
Pubmed	MYC multimers shield stalled replication forks from RNA polymerase.	ELOA DSP MCM4 FAM98B RFC1 KIF20B ZNF106 ANLN FRG1 PUM3 BOD1L1 MRTO4 RPL7A TOP2B	6.46e-07	989	97	14	36424410
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	SH3RF1 MAP1B DSP USP24 ABCC5 MCM4 CCDC88A BOD1L1 DIAPH3 ATP2B1 RPL7A NCK2	6.79e-07	708	97	12	39231216
Pubmed	Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.	ELOA RFC1 EMSY RPRD2 BOD1L1 TAF1 TAF1L TOP2B	1.35e-06	283	97	8	30585729
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	ELOA MAP1B NSD2 RFC1 DDX55 KIF20B FRG1 PUM3 MRTO4 IQGAP3 RPL7A TOP2B	1.40e-06	759	97	12	35915203
Pubmed	Human Regulatory Protein Ki-1/57 Is a Target of SUMOylation and Affects PML Nuclear Body Formation.	ELOA FAM98B DDX55 GTF2F1 PUM3 MRTO4	2.17e-06	134	97	6	28695742
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	WIPF1 DOCK8 CHD9 MCM4 FAM98B RFC1 DDX55 EMSY GTF2F1 ANLN FRG1 PUM3 MRTO4 TOP2B	2.32e-06	1103	97	14	34189442
Pubmed	STING-Mediated IFI16 Degradation Negatively Controls Type I Interferon Production.	ELOA MAP1B SIPA1L3 RFC1 DDX55 AP2A2 PUM3 RPL7A	3.05e-06	316	97	8	31665637
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	MAP1B DSP USP24 EMSY GGA3 ANLN RPRD2 BOD1L1 TAF1 DIAPH3	3.26e-06	549	97	10	38280479
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	INTU MAP1B NSD2 SIPA1L3 CHD9 BCR C2CD2 HIVEP3 ARHGAP6 RPRD2 BOD1L1 CHD6 ZNF839 MLPH ATP2B1 NCK2	3.53e-06	1489	97	16	28611215
Pubmed	Functional proteomics mapping of a human signaling pathway.	DOCK8 GGA3 ZNF106 MAST4 AP2A2 PLCL2 CHD6 DIAPH3 SMAD2 SMAD3	6.22e-06	591	97	10	15231748
Pubmed	MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.	MAP1B MCM4 SYNE2 PUM3 RPRD2 TAF1 ATP2B1 TOP2B	7.60e-06	358	97	8	32460013
Pubmed	TAFII250 is a bipartite protein kinase that phosphorylates the base transcription factor RAP74.	GTF2F1 TAF1	7.70e-06	2	97	2	8625415
Pubmed	Smad2 and Smad3 have differential sensitivity in relaying TGFβ signaling and inversely regulate early lineage specification.	SMAD2 SMAD3	7.70e-06	2	97	2	26905010
Pubmed	Multiple novel nesprin-1 and nesprin-2 variants act as versatile tissue-specific intracellular scaffolds.	SYNE1 SYNE2	7.70e-06	2	97	2	22768332
Pubmed	Cigarette smoke exacerbates mouse allergic asthma through Smad proteins expressed in mast cells.	SMAD2 SMAD3	7.70e-06	2	97	2	21496353
Pubmed	Lack of extracellular matrix switches TGF-β induced apoptosis of endometrial cells to epithelial to mesenchymal transition.	SMAD2 SMAD3	7.70e-06	2	97	2	36050359
Pubmed	Receptor-regulated and inhibitory Smads are critical in regulating transforming growth factor beta-mediated Meckel's cartilage development.	SMAD2 SMAD3	7.70e-06	2	97	2	11984875
Pubmed	Reduction of Smad2 caused by oxidative stress leads to necrotic death of hypertrophic chondrocytes associated with an endemic osteoarthritis.	SMAD2 SMAD3	7.70e-06	2	97	2	33769459
Pubmed	Polycomb determines responses to smad2/3 signaling in embryonic stem cell differentiation and in reprogramming.	SMAD2 SMAD3	7.70e-06	2	97	2	23666711
Pubmed	Acceleration of Smad2 and Smad3 phosphorylation via c-Jun NH(2)-terminal kinase during human colorectal carcinogenesis.	SMAD2 SMAD3	7.70e-06	2	97	2	15665291
Pubmed	Inhibiting Smad2/3 signaling in pluripotent mouse embryonic stem cells enhances endoderm formation by increasing transcriptional priming of lineage-specifying target genes.	SMAD2 SMAD3	7.70e-06	2	97	2	27012147
Pubmed	Phosphorylated Smad2/3 immunoreactivity in sporadic and familial amyotrophic lateral sclerosis and its mouse model.	SMAD2 SMAD3	7.70e-06	2	97	2	18210139
Pubmed	Opposing roles for Smad2 and Smad3 in peritoneal fibrosis in vivo and in vitro.	SMAD2 SMAD3	7.70e-06	2	97	2	24925688
Pubmed	Role of Rho/ROCK and p38 MAP kinase pathways in transforming growth factor-beta-mediated Smad-dependent growth inhibition of human breast carcinoma cells in vivo.	SMAD2 SMAD3	7.70e-06	2	97	2	15520018
Pubmed	Nesprins: a novel family of spectrin-repeat-containing proteins that localize to the nuclear membrane in multiple tissues.	SYNE1 SYNE2	7.70e-06	2	97	2	11792814
Pubmed	Nuclear exclusion of SMAD2/3 in granulosa cells is associated with primordial follicle activation in the mouse ovary.	SMAD2 SMAD3	7.70e-06	2	97	2	30111581
Pubmed	The DNA binding activities of Smad2 and Smad3 are regulated by coactivator-mediated acetylation.	SMAD2 SMAD3	7.70e-06	2	97	2	17074756
Pubmed	Smad2 and Smad3 have opposing roles in breast cancer bone metastasis by differentially affecting tumor angiogenesis.	SMAD2 SMAD3	7.70e-06	2	97	2	20010874
Pubmed	Nesprin-1 and nesprin-2 regulate endothelial cell shape and migration.	SYNE1 SYNE2	7.70e-06	2	97	2	24931616
Pubmed	Kinase activity and phosphorylation of the largest subunit of TFIIF transcription factor.	GTF2F1 TAF1	7.70e-06	2	97	2	10428810
Pubmed	Deletion of Smad2 in mouse liver reveals novel functions in hepatocyte growth and differentiation.	SMAD2 SMAD3	7.70e-06	2	97	2	16382155
Pubmed	Molecular validation of the precision-cut kidney slice (PCKS) model of renal fibrosis through assessment of TGF-β1-induced Smad and p38/ERK signaling.	SMAD2 SMAD3	7.70e-06	2	97	2	26919280
Pubmed	Smad2 and Smad3 expressed in skeletal muscle promote immobilization-induced bone atrophy in mice.	SMAD2 SMAD3	7.70e-06	2	97	2	34710825
Pubmed	Evidence for a role of Smad3 and Smad2 in stabilization of the tumor-derived mutant Smad2.Q407R.	SMAD2 SMAD3	7.70e-06	2	97	2	12700238
Pubmed	Asthma-derived fibroblast to myofibroblast transition is enhanced in comparison to fibroblasts derived from non-asthmatic patients in 3D in vitro culture due to Smad2/3 signalling.	SMAD2 SMAD3	7.70e-06	2	97	2	33245228
Pubmed	Syne-1 and Syne-2 play crucial roles in myonuclear anchorage and motor neuron innervation.	SYNE1 SYNE2	7.70e-06	2	97	2	17267447
Pubmed	Formation of the definitive endoderm in mouse is a Smad2-dependent process.	SMAD2 SMAD3	7.70e-06	2	97	2	10862745
Pubmed	Smad2-dependent downregulation of miR-30 is required for TGF-β-induced apoptosis in podocytes.	SMAD2 SMAD3	7.70e-06	2	97	2	24086574
Pubmed	Nesprins: tissue-specific expression of epsilon and other short isoforms.	SYNE1 SYNE2	7.70e-06	2	97	2	24718612
Pubmed	Signaling via Smad2 and Smad3 is dispensable for adult murine hematopoietic stem cell function in vivo.	SMAD2 SMAD3	7.70e-06	2	97	2	28666967
Pubmed	The specific linker phosphorylation of Smad2/3 indicates epithelial stem cells in stomach; particularly increasing in mucosae of Helicobacter-associated gastritis.	SMAD2 SMAD3	7.70e-06	2	97	2	21229365
Pubmed	Targeted ablation of nesprin 1 and nesprin 2 from murine myocardium results in cardiomyopathy, altered nuclear morphology and inhibition of the biomechanical gene response.	SYNE1 SYNE2	7.70e-06	2	97	2	24586179
Pubmed	Signaling network crosstalk in human pluripotent cells: a Smad2/3-regulated switch that controls the balance between self-renewal and differentiation.	SMAD2 SMAD3	7.70e-06	2	97	2	22385658
Pubmed	Mice exclusively expressing the short isoform of Smad2 develop normally and are viable and fertile.	SMAD2 SMAD3	7.70e-06	2	97	2	15630024
Pubmed	Specific Smad2/3 Linker Phosphorylation Indicates Esophageal Non-neoplastic and Neoplastic Stem-Like Cells and Neoplastic Development.	SMAD2 SMAD3	7.70e-06	2	97	2	32705438
Pubmed	Taf1 knockout is lethal in embryonic male mice and heterozygous females show weight and movement disorders.	TAF1 TAF1L	7.70e-06	2	97	2	38804708
Pubmed	Smad2/3 Linker Phosphorylation Is a Possible Marker of Pancreatic Stem/Progenitor Cells in the Regenerative Phase of Acute Pancreatitis.	SMAD2 SMAD3	7.70e-06	2	97	2	28099259
Pubmed	Arsenite Disrupts Zinc-Dependent TGFβ2-SMAD Activity During Murine Cardiac Progenitor Cell Differentiation.	SMAD2 SMAD3	7.70e-06	2	97	2	26354774
Pubmed	Differential effects of Smad2 and Smad3 in regulation of macrophage phenotype and function in the infarcted myocardium.	SMAD2 SMAD3	7.70e-06	2	97	2	35780861
Pubmed	Nesprin-1 and -2 are involved in the pathogenesis of Emery Dreifuss muscular dystrophy and are critical for nuclear envelope integrity.	SYNE1 SYNE2	7.70e-06	2	97	2	17761684
Pubmed	TAFII250, Egr-1, and D-type cyclin expression in mice and neonatal rat cardiomyocytes treated with doxorubicin.	TAF1 TAF1L	7.70e-06	2	97	2	10070062
Pubmed	Characterization of Ggrb4, an adapter protein interacting with Bcr-Abl.	BCR NCK2	7.70e-06	2	97	2	10887126
Pubmed	Implication of Smad2 and Smad3 in transforming growth factor-β-induced posterior capsular opacification of human lens epithelial cells.	SMAD2 SMAD3	7.70e-06	2	97	2	24911914
Pubmed	Sustained expression of a neuron-specific isoform of the Taf1 gene in development stages and aging in mice.	TAF1 TAF1L	7.70e-06	2	97	2	22842574
Pubmed	Constitutively Active SMAD2/3 Are Broad-Scope Potentiators of Transcription-Factor-Mediated Cellular Reprogramming.	SMAD2 SMAD3	7.70e-06	2	97	2	29174331
Pubmed	Nesprin-1-alpha2 associates with kinesin at myotube outer nuclear membranes, but is restricted to neuromuscular junction nuclei in adult muscle.	SYNE1 SYNE2	7.70e-06	2	97	2	31578382
Pubmed	Graded Smad2/3 activation is converted directly into levels of target gene expression in embryonic stem cells.	SMAD2 SMAD3	7.70e-06	2	97	2	19172185
Pubmed	The role of a Williams-Beuren syndrome-associated helix-loop-helix domain-containing transcription factor in activin/nodal signaling.	SMAD2 SMAD3	7.70e-06	2	97	2	11937490
Pubmed	Frameshift Mutations in the Mononucleotide Repeats of TAF1 and TAF1L Genes in Gastric and Colorectal Cancers with Regional Heterogeneity.	TAF1 TAF1L	7.70e-06	2	97	2	27571988
Pubmed	The roles of Smad2 and Smad3 in the development of chemically induced skin tumors in mice.	SMAD2 SMAD3	7.70e-06	2	97	2	15133179
Pubmed	Striatal Cholinergic Dysregulation after Neonatal Decrease in X-Linked Dystonia Parkinsonism-Related TAF1 Isoforms.	TAF1 TAF1L	7.70e-06	2	97	2	34403156
Pubmed	Oocytes determine cumulus cell lineage in mouse ovarian follicles.	SMAD2 SMAD3	7.70e-06	2	97	2	17389684
Pubmed	SMAD2/3 Phosphorylation Is Downregulated in T Cells in HIV-Infected Patients.	SMAD2 SMAD3	7.70e-06	2	97	2	36226468
Pubmed	[Expression and significance of Smad2/3 and HPV16 E7 in cervical intraepithelial neoplasia and cervical carcinoma].	SMAD2 SMAD3	7.70e-06	2	97	2	17927854
Pubmed	Hydrophobic patches on SMAD2 and SMAD3 determine selective binding to cofactors.	SMAD2 SMAD3	7.70e-06	2	97	2	29588413
Pubmed	Phosphorylation of Smad2/3 at specific linker threonine indicates slow-cycling intestinal stem-like cells before reentry to cell cycle.	SMAD2 SMAD3	7.70e-06	2	97	2	25185661
Pubmed	Neovibsanin B increases extracellular matrix proteins in optic nerve head cells via activation of Smad signalling pathway.	SMAD2 SMAD3	7.70e-06	2	97	2	26045877
Pubmed	Increased TGF-β1-mediated suppression of growth and motility in castrate-resistant prostate cancer cells is consistent with Smad2/3 signaling.	SMAD2 SMAD3	7.70e-06	2	97	2	22228025
Pubmed	Oocyte-secreted factor activation of SMAD 2/3 signaling enables initiation of mouse cumulus cell expansion.	SMAD2 SMAD3	7.70e-06	2	97	2	17192514
Pubmed	Smad2/3 Activation Regulates Smad1/5/8 Signaling via a Negative Feedback Loop to Inhibit 3T3-L1 Adipogenesis.	SMAD2 SMAD3	7.70e-06	2	97	2	34445177
Pubmed	Essential role of Smad3 in angiotensin II-induced vascular fibrosis.	SMAD2 SMAD3	7.70e-06	2	97	2	16556868
Pubmed	Cell biology of Smad2/3 linker region phosphorylation in vascular smooth muscle.	SMAD2 SMAD3	7.70e-06	2	97	2	21883378
Pubmed	[The roles of Smad 2/3 in transforming growth factor-beta 1 signaling in human dental pulp cells].	SMAD2 SMAD3	7.70e-06	2	97	2	12760775
Pubmed	TGFβ pathway deregulation and abnormal phospho-SMAD2/3 staining in hereditary cerebral hemorrhage with amyloidosis-Dutch type.	SMAD2 SMAD3	7.70e-06	2	97	2	28557134
Pubmed	Differential Role of Smad2 and Smad3 in the Acquisition of an Endovascular Trophoblast-Like Phenotype and Preeclampsia.	SMAD2 SMAD3	7.70e-06	2	97	2	32733385
Pubmed	Smad2/3 linker phosphorylation is a possible marker of cancer stem cells and correlates with carcinogenesis in a mouse model of colitis-associated colorectal cancer.	SMAD2 SMAD3	7.70e-06	2	97	2	25908723
Pubmed	Differential activation of noncanonical SMAD2/SMAD3 signaling by bone morphogenetic proteins causes disproportionate induction of hyaluronan production in immortalized human granulosa cells.	SMAD2 SMAD3	7.70e-06	2	97	2	26992562
Pubmed	Global analysis of Smad2/3-dependent TGF-beta signaling in living mice reveals prominent tissue-specific responses to injury.	SMAD2 SMAD3	7.70e-06	2	97	2	15972691
Pubmed	Enrichment of human ESC-derived multipotent mesenchymal stem cells with immunosuppressive and anti-inflammatory properties capable to protect against experimental inflammatory bowel disease.	SMAD2 SMAD3	7.70e-06	2	97	2	21732483
Pubmed	Smad2 and 3 transcription factors control muscle mass in adulthood.	SMAD2 SMAD3	7.70e-06	2	97	2	19357234
Pubmed	Expression pattern and phosphorylation status of Smad2/3 in different subtypes of human first trimester trophoblast.	SMAD2 SMAD3	7.70e-06	2	97	2	28864007
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	DSP USP24 MCM4 FAM98B RFC1 DDX55 GTF2F1 AP2A2 FRG1 SYNE2 MRTO4 EIF3B DIAPH3 RPL7A TOP2B	8.67e-06	1415	97	15	28515276
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	DSP NSD2 SYNE1 MCM4 RFC1 DDX55 AP2A2 PUM3 BOD1L1 MRTO4 EIF3B ATP2B1 IQGAP3 RPL7A TOP2B	9.42e-06	1425	97	15	30948266
Pubmed	Elf5-centered transcription factor hub controls trophoblast stem cell self-renewal and differentiation through stoichiometry-sensitive shifts in target gene networks.	MAP1B RFC1 EMSY RPL7A TOP2B	1.02e-05	102	97	5	26584622
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	ELOA DSP SIPA1L3 RFC1 DDX55 KIF20B ANLN FRG1 GSDMA PUM3 MRTO4 EIF3B IQGAP3 RPL7A	1.03e-05	1257	97	14	36526897
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	MAP1B DSP NSD2 USP24 MCM4 RFC1 SYNE2 PUM3 MRTO4 RPL7A	1.48e-05	653	97	10	22586326
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	DSP SYNE1 CNTRL HIVEP3 RTKN2 LLGL2 AP2A2 EIF3B IQGAP3 RPL7A MYO16	1.59e-05	807	97	11	30575818
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	NSD2 MTSS1 DDX55 BCR GGA3 CCDC88A MAST4 AKAP11 RPRD2	1.78e-05	529	97	9	14621295
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	INTU SYNE1 MAP3K4 GGA3 PLCL2 BOD1L1 CHD6 PLCE1	1.91e-05	407	97	8	12693553
Interaction	POLR1G interactions	ELOA NSD2 CHD9 RFC1 DDX55 KIF20B ZNF106 GTF2F1 PUM3 RPRD2 TAF1 RPL7A TOP2B	4.91e-07	489	95	13	int:POLR1G
Interaction	POLR1E interactions	ELOA EMSY ZNF106 GTF2F1 ANLN ATG12 RPRD2 MRTO4 CHD6 TAF1 TOP2B	7.88e-07	350	95	11	int:POLR1E
Interaction	IFI16 interactions	ELOA MAP1B NSD2 SYNE1 SIPA1L3 MCM4 RFC1 DDX55 AP2A2 ANLN GSDMA PUM3 MRTO4 RPL7A TOP2B	1.19e-06	714	95	15	int:IFI16
Interaction	ZNF330 interactions	ELOA NSD2 RFC1 DDX55 ZNF106 GTF2F1 ANLN FRG1 PUM3 TAF1 RPL7A TOP2B	1.24e-06	446	95	12	int:ZNF330
Interaction	RHOB interactions	ELOA SIPA1L3 ABCC5 BCR C2CD2 RTKN2 CCDC88A ANLN VPS13A MRTO4 DIAPH3 DEPDC7 ATP2B1 IQGAP3 RPL7A TOP2B	1.82e-06	840	95	16	int:RHOB
Interaction	H1-5 interactions	DSP NSD2 SYNE1 CNTRL TAAR3P ABCC5 EMSY IQCA1L ANLN PUM3 RPRD2 ATP2B1	1.83e-06	463	95	12	int:H1-5
Interaction	ANKRD20A4P interactions	ANKRD20A2P ANKRD20A4P ANKRD20A1	2.01e-06	6	95	3	int:ANKRD20A4P
Interaction	KCNA3 interactions	SH3RF1 MAP1B DSP USP24 ABCC5 CHD9 MCM4 CCDC88A VPS13A BOD1L1 RP1 DIAPH3 ATP2B1 IQGAP3 RPL7A NCK2	2.90e-06	871	95	16	int:KCNA3
Interaction	ANKRD20A2P interactions	ANKRD20A2P ANKRD20A4P ANKRD20A1	3.50e-06	7	95	3	int:ANKRD20A2P
Interaction	RPL31 interactions	ELOA NSD2 RFC1 DDX55 ZNF106 GTF2F1 ANLN FRG1 PUM3 MRTO4 EIF3B TAF1 RPL7A TOP2B	3.55e-06	680	95	14	int:RPL31
Interaction	H3C3 interactions	ELOA NSD2 RFC1 DDX55 KIF20B ANLN FRG1 PUM3 BOD1L1 CHD6 TAF1 TOP2B	3.63e-06	495	95	12	int:H3C3
Interaction	SMC5 interactions	ELOA SLF1 MAP1B DSP NSD2 MCM4 FAM98B RFC1 KIF20B EMSY ANLN PUM3 RPRD2 BOD1L1 TAF1 TAF1L TOP2B	3.87e-06	1000	95	17	int:SMC5
Interaction	BRCA1 interactions	ELOA SLF1 HECTD3 DSP NSD2 CHD9 MCM4 RFC1 HIBADH KIF20B EMSY RTKN2 GTF2F1 ANLN EIF3B RPL7A TOP2B SMAD2 SMAD3	4.86e-06	1249	95	19	int:BRCA1
Interaction	NUP43 interactions	DSP NSD2 CHD9 RFC1 DDX55 EMSY CCDC88A FRG1 SYNE2 BOD1L1 CHD6 RPL7A TOP2B	7.34e-06	625	95	13	int:NUP43
Interaction	CENPA interactions	NSD2 MCM4 RFC1 DDX55 GTF2F1 FRG1 CHD6 TAF1 DIAPH3 TOP2B	1.15e-05	377	95	10	int:CENPA
Interaction	ANKRD20A1 interactions	ANKRD20A2P ANKRD20A4P ANKRD20A1	1.63e-05	11	95	3	int:ANKRD20A1
Interaction	PHF21A interactions	DSP USP24 BCR KIF20B CCDC88A LLGL2 CHD6 TAF1 DIAPH3	3.51e-05	343	95	9	int:PHF21A
Interaction	NIFK interactions	ELOA RFC1 DDX55 ZNF106 GTF2F1 ANLN PUM3 MRTO4 RPL7A TOP2B	3.61e-05	431	95	10	int:NIFK
Interaction	PSMD14 interactions	SH3RF1 DSP CNTRL BCR NLRP9 SYNE2 CHD6 RP1 HADH TOP2B BBOF1	3.79e-05	527	95	11	int:PSMD14
Interaction	CDC42 interactions	WIPF1 DSP DOCK8 SYNE1 ABCC5 BCR C2CD2 MAP3K4 CCDC88A AP2A2 ANLN SYNE2 VPS13A HADH DIAPH3 ATP2B1 IQGAP3 TOP2B	4.01e-05	1323	95	18	int:CDC42
Interaction	RHOJ interactions	DOCK8 USP24 ABCC5 C2CD2 CCDC88A VPS13A MRTO4 DIAPH3 ATP2B1 IQGAP3 TOP2B SMAD2	4.21e-05	633	95	12	int:RHOJ
Interaction	H3-3A interactions	ELOA NSD2 CHD9 RFC1 DDX55 KIF20B EMSY ANLN FRG1 PUM3 BOD1L1 TAF1 TOP2B	4.89e-05	749	95	13	int:H3-3A
Interaction	TERF2IP interactions	ELOA NSD2 RFC1 DDX55 KIF20B EMSY GTF2F1 ANLN BOD1L1 MRTO4 TAF1	5.76e-05	552	95	11	int:TERF2IP
Interaction	RPS6 interactions	ELOA NSD2 RFC1 DDX55 ANKRD18B ZNF106 GVINP1 ANLN PUM3 MRTO4 CHD6 EIF3B RPL7A TOP2B	5.84e-05	874	95	14	int:RPS6
Interaction	S100A4 interactions	CNTRL SYNE2 RPRD2 DIAPH3 SMAD2 SMAD3	6.18e-05	144	95	6	int:S100A4
Interaction	METTL14 interactions	DSP MCM4 KIF20B AP2A2 ANLN ATG12 C18orf63 RPL7A TOP2B SMAD2 SMAD3	6.34e-05	558	95	11	int:METTL14
Interaction	H3C1 interactions	ELOA DSP NSD2 SYNE1 MCM4 RFC1 KIF20B ANKRD18B GTF2F1 ANLN FRG1 TAF1 RPL7A TOP2B	8.08e-05	901	95	14	int:H3C1
Interaction	H2BC8 interactions	ELOA NSD2 RFC1 DDX55 KIF20B GTF2F1 ANLN FRG1 AKAP11 CHD6 TOP2B	8.41e-05	576	95	11	int:H2BC8
Interaction	MEN1 interactions	RFC1 DDX55 EMSY ANLN FRG1 ATG12 PUM3 BOD1L1 MRTO4 TAF1 RPL7A TOP2B CAVIN2 SMAD2 SMAD3	8.99e-05	1029	95	15	int:MEN1
Interaction	RHOC interactions	ABCC5 BCR C2CD2 RTKN2 CCDC88A ANLN SYNE2 VPS13A DIAPH3 ATP2B1 IQGAP3	9.51e-05	584	95	11	int:RHOC
Interaction	ADARB1 interactions	NSD2 MCM4 RFC1 DDX55 ANLN PUM3 RPRD2 MRTO4 RPL7A TOP2B	1.03e-04	489	95	10	int:ADARB1
Interaction	RASL12 interactions	ANLN SMAD2 SMAD3	1.09e-04	20	95	3	int:RASL12
Interaction	XRCC6 interactions	ELOA MAP1B NSD2 RFC1 EMSY GTF2F1 ANLN RPRD2 BOD1L1 TAF1 TAF1L TOP2B SMAD2 SMAD3	1.10e-04	928	95	14	int:XRCC6
Interaction	PAPPA interactions	RTKN2 SMAD2 SMAD3	1.46e-04	22	95	3	int:PAPPA
Interaction	WWTR1 interactions	MAP1B USP24 EMSY GGA3 ANLN ATG12 RPRD2 DIAPH3 SMAD2	1.70e-04	422	95	9	int:WWTR1
Interaction	ASF1A interactions	MCM4 KIF20B EMSY GTF2F1 ANLN CHD6 TAF1	1.77e-04	249	95	7	int:ASF1A
Interaction	NR3C1 interactions	HECTD3 DSP USP24 CHD9 RFC1 FER1L6 ANLN SYNE2 VPS13A CHD6 TTC5 ATP2B1 CAVIN2 SMAD3	1.83e-04	974	95	14	int:NR3C1
Interaction	DOCK9 interactions	ATG12 TAF1 SMAD2 SMAD3	1.97e-04	61	95	4	int:DOCK9
Interaction	GTPBP4 interactions	NSD2 DDX55 BCR GGA3 LLGL2 ANLN PUM3 MRTO4 RPL7A	2.44e-04	443	95	9	int:GTPBP4
Interaction	CLTA interactions	DOCK8 SIPA1L3 BCR GGA3 MAST4 AP2A2 ANLN RPL7A	2.55e-04	351	95	8	int:CLTA
Interaction	ARHGAP26 interactions	ELOA C2CD2 SYNE2 MYO16 NCK2	2.60e-04	120	95	5	int:ARHGAP26
Interaction	ATRX interactions	NSD2 MCM4 RFC1 BCR GTF2F1 EIF3B RPL7A	2.71e-04	267	95	7	int:ATRX
Interaction	COIL interactions	ELOA NSD2 CHD9 GTF2F1 ANLN FRG1 CHD6 TAF1 RPL7A TOP2B	2.75e-04	552	95	10	int:COIL
Interaction	DENND2B interactions	LLGL2 ANLN SMAD2	3.05e-04	28	95	3	int:DENND2B
Interaction	NINL interactions	ELOA SH3RF1 DSP SIPA1L3 BCR MAST4 RPRD2 DIAPH3 IQGAP3	3.12e-04	458	95	9	int:NINL
Interaction	RHOF interactions	DOCK8 SIPA1L3 ABCC5 C2CD2 CCDC88A VPS13A MRTO4 DIAPH3 ATP2B1 IQGAP3 TOP2B	3.25e-04	673	95	11	int:RHOF
Interaction	ONECUT3 interactions	SH3RF1 NCK2	3.26e-04	6	95	2	int:ONECUT3
Interaction	ANTXR2 interactions	ELOA RPL7A SMAD2	3.39e-04	29	95	3	int:ANTXR2
Interaction	NOP56 interactions	ELOA RFC1 DDX55 ZNF106 GTF2F1 ANLN PUM3 MRTO4 RPL7A TOP2B	3.54e-04	570	95	10	int:NOP56
Interaction	SLX4 interactions	ELOA DSP CHD9 EMSY ZNF106 GTF2F1 AP2A2 GSDMA RPRD2 IQGAP3	3.64e-04	572	95	10	int:SLX4
Interaction	AKR7L interactions	ELOA RFC1 DDX55 GTF2F1	3.73e-04	72	95	4	int:AKR7L
Interaction	ANK3 interactions	MCM4 BCR OTUD7A ATP2B1 SMAD2 SMAD3	3.80e-04	201	95	6	int:ANK3
Interaction	RBBP5 interactions	DSP EMSY FRG1 BOD1L1 TAF1 SMAD2 SMAD3	4.19e-04	287	95	7	int:RBBP5
Interaction	YWHAZ interactions	ELOA SH3RF1 CLIP2 SIPA1L3 BCR MAP3K4 CCDC88A MAST4 ANLN SYNE2 GSDMA PUM3 AKAP11 ZNF839 ATP2B1 RPL7A	4.20e-04	1319	95	16	int:YWHAZ
Interaction	DDX23 interactions	ELOA MAP1B SYNE1 MCM4 DDX55 GTF2F1 PUM3 TAF1 TOP2B	4.39e-04	480	95	9	int:DDX23
Interaction	RAC1 interactions	SH3RF1 DOCK8 SIPA1L3 ABCC5 BCR C2CD2 MAP3K4 CCDC88A LLGL2 AP2A2 VPS13A DIAPH3 ATP2B1 IQGAP3	4.45e-04	1063	95	14	int:RAC1
Interaction	NPM1 interactions	MAP1B DSP NSD2 LEMD1 RFC1 DDX55 GGA3 ANLN SYNE2 PUM3 AKAP11 RP1 RPL7A TOP2B CAVIN2	4.79e-04	1201	95	15	int:NPM1
Interaction	GNL2 interactions	ELOA RFC1 DDX55 KIF20B GTF2F1 ANLN MRTO4 RPL7A	4.80e-04	386	95	8	int:GNL2
Interaction	NECAP1 interactions	NSD2 MCM4 AP2A2 TOP2B	5.06e-04	78	95	4	int:NECAP1
Interaction	NXF1 interactions	MAP1B ABCC5 MCM4 FAM98B EMSY GGA3 ZNF106 AP2A2 ANLN PLCL2 PUM3 TAF1 HADH DIAPH3 DEPDC7 TAF1L	5.20e-04	1345	95	16	int:NXF1
Interaction	HEY1 interactions	SYNE1 CCDC88A FRG1 SYNE2 SMAD3	5.29e-04	140	95	5	int:HEY1
GeneFamily	Ankyrin repeat domain containing	SLF1 ANKRD20A2P ANKRD20A3P ANKRD18B ANKRD20A4P MYO16 ANKRD20A1	1.85e-05	242	62	7	403
GeneFamily	Spectrin repeat containing nuclear envelope family	SYNE1 SYNE2	6.91e-05	4	62	2	1252
GeneFamily	SMAD family	SMAD2 SMAD3	3.20e-04	8	62	2	750
GeneFamily	Phospholipases\|C2 domain containing phospholipases	PLCL2 PLCE1	1.91e-03	19	62	2	832
Coexpression	GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN3_THYMOCYTE_FETAL_DN	SYNE1 ABCC5 HIBADH HIVEP3 LLGL2 ATG12 SYNE2 NCK2	6.63e-07	199	95	8	M4571
Coexpression	HALLMARK_MITOTIC_SPINDLE	CLIP2 CNTRL RFC1 BCR KIF20B CCDC88A ANLN NCK2	6.63e-07	199	95	8	M5893
Coexpression	GSE10147_IL3_VS_IL3_AND_HIVP17_STIM_PDC_UP	DOCK8 GGA3 ZNF106 CCDC88A ATG12 AKAP11 RPRD2	2.49e-06	166	95	7	M344
Coexpression	HE_LIM_SUN_FETAL_LUNG_C4_CYCLING_T_CELL	SLF1 NSD2 CNTRL MCM4 FAM98B KIF20B RTKN2 CCDC88A MAST4 ANLN SYNE2 PLCL2 HADH DIAPH3	7.17e-06	939	95	14	M45768
Coexpression	HE_LIM_SUN_FETAL_LUNG_C5_LARGE_PRE_B_CELL	SLF1 NSD2 MCM4 FAM98B RFC1 DDX55 BCR HIBADH KIF20B RTKN2 CCDC88A ANLN SYNE2 MRTO4 EIF3B HADH DIAPH3	7.32e-06	1363	95	17	M45782
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	MAP1B USP24 CHD9 C2CD2 KIF20B MAP3K4 SYNE2 VPS13A PUM3 AKAP11 ATP2B1 SMAD3 PLCE1	1.29e-05	856	95	13	M4500
Coexpression	BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_A	ANKRD20A3P ANKRD20A8P ANKRD18B MAP3K4 HIVEP3 GTF2F1 ANKRD20A4P SYNE2 PLCL2 GSDMA CHD6 ATP2B1 ANKRD20A1	3.08e-05	930	95	13	MM893
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN	MAP1B USP24 CHD9 C2CD2 KIF20B VPS13A PUM3 ATP2B1 SMAD3	5.00e-05	466	95	9	M13522
Coexpression	RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_UP	MCM4 RFC1 KIF20B CCDC88A ANLN ATG12 PUM3 BOD1L1 DIAPH3 DEPDC7 ATP2B1	6.06e-05	721	95	11	M10237
Coexpression	IWANAGA_CARCINOGENESIS_BY_KRAS_UP	ANKRD20A3P ANKRD20A8P ANKRD18B ANKRD20A4P BOD1L1 ANKRD20A1	7.23e-05	192	95	6	MM752
Coexpression	GSE21670_UNTREATED_VS_TGFB_IL6_TREATED_CD4_TCELL_UP	NSD2 BCR RTKN2 ANLN SYNE2 PLCL2	7.66e-05	194	95	6	M7467
Coexpression	GSE37533_PPARG1_FOXP3_VS_FOXP3_TRANSDUCED_CD4_TCELL_PIOGLITAZONE_TREATED_DN	NSD2 ABCC5 CCDC88A GVINP1 EIF3B NCK2	8.81e-05	199	95	6	M8974
Coexpression	GSE37534_UNTREATED_VS_GW1929_TREATED_CD4_TCELL_PPARG1_AND_FOXP3_TRASDUCED_DN	ABCC5 GBP2 HIVEP3 CCDC88A AKAP11 EIF3B	8.81e-05	199	95	6	M8979
Coexpression	GSE18893_TCONV_VS_TREG_24H_TNF_STIM_DN	MTSS1 USP24 HIBADH HIVEP3 MTRR TOP2B	8.81e-05	199	95	6	M7291
Coexpression	GSE10325_CD4_TCELL_VS_MYELOID_UP	SYNE1 BCR MAST4 GVINP1 SYNE2 NCK2	8.81e-05	199	95	6	M3078
Coexpression	GSE28237_EARLY_VS_LATE_GC_BCELL_DN	HECTD3 DSP PLCL2 PUM3 RPRD2 PLCE1	9.05e-05	200	95	6	M4894
Coexpression	GSE45881_CXCR6HI_VS_CXCR1LO_COLONIC_LAMINA_PROPRIA_UP	HECTD3 USP24 GBP2 MAP3K4 MAST4 VPS13A	9.05e-05	200	95	6	M9889
Coexpression	GSE12392_WT_VS_IFNB_KO_CD8A_NEG_SPLEEN_DC_UP	ELOA SYNE1 MAP3K4 PUM3 HADH DEPDC7	9.05e-05	200	95	6	M7148
Coexpression	GSE39820_CTRL_VS_IL1B_IL6_CD4_TCELL_DN	SH3RF1 DSP MTSS1 ATG12 HADH SMAD3	9.05e-05	200	95	6	M5600
Coexpression	GEORGES_TARGETS_OF_MIR192_AND_MIR215	ELOA SLF1 NSD2 MTSS1 HIBADH KIF20B RTKN2 ANLN AKAP11 HADH PLCE1 BBOF1	9.17e-05	892	95	12	M18120
Coexpression	GU_PDEF_TARGETS_UP	WIPF1 SMAD2 SMAD3 PLCE1	1.31e-04	71	95	4	M3955
Coexpression	HAMAI_APOPTOSIS_VIA_TRAIL_UP	SLF1 RFC1 KIF20B CCDC88A ANLN SYNE2 PUM3 AKAP11 DIAPH3 TOP2B	1.35e-04	656	95	10	M18979
Coexpression	LAKE_ADULT_KIDNEY_C3_PROXIMAL_TUBULE_EPITHELIAL_CELLS_S1_S2	CHD9 ARHGAP6 MAST4 SYNE2 VPS13A PUM3	1.56e-04	221	95	6	M39222
Coexpression	TRAVAGLINI_LUNG_CILIATED_CELL	DNAH3 INTU MAP1B DSP SYNE1 CNTRL HIBADH ZNF106 LRRIQ1 SYNE2 RP1 HADH TTC5	1.57e-04	1093	95	13	M41649
Coexpression	DAZARD_UV_RESPONSE_CLUSTER_G6	USP24 CHD9 MAST4 ATP2B1 SMAD3	1.88e-04	145	95	5	M1810
Coexpression	FISCHER_DREAM_TARGETS	SLF1 NSD2 MCM4 RFC1 KIF20B RTKN2 ANLN MRTO4 EIF3B HADH DIAPH3 IQGAP3	1.98e-04	969	95	12	M149
Coexpression	KOINUMA_TARGETS_OF_SMAD2_OR_SMAD3	SH3RF1 CLIP2 DSP CHD9 BCR MAST4 ANLN ATG12 SYNE2 DEPDC7 SMAD3	2.38e-04	843	95	11	M2356
Coexpression	DOANE_RESPONSE_TO_ANDROGEN_DN	DSP NSD2 ABCC5 MCM4 MAST4 SMAD3	2.55e-04	242	95	6	M12816
Coexpression	FAN_EMBRYONIC_CTX_MICROGLIA_1	CNTRL KIF20B ANLN DIAPH3 IQGAP3	2.56e-04	155	95	5	M39041
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ELOA DSP CNTRL CHD9 ZNF106 SYNE2 AKAP11 TOP2B	9.53e-09	191	97	8	60c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ELOA DSP CNTRL CHD9 ZNF106 SYNE2 AKAP11 TOP2B	9.53e-09	191	97	8	09db184cb90fe282a14474d7217068c58092c6f8
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ELOA DSP CNTRL CHD9 ZNF106 SYNE2 AKAP11 TOP2B	9.53e-09	191	97	8	973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
ToppCell	COPD-Multiplet-Multiplet\|COPD / Disease state, Lineage and Cell class	DNAH3 SH3RF1 SYNE1 LRRIQ1 MAST4 SYNE2 RP1 BBOF1	1.17e-08	196	97	8	af4cdc61830685a888a1209826c23bcf54a43084
ToppCell	COPD-Multiplet\|COPD / Disease state, Lineage and Cell class	DNAH3 SH3RF1 SYNE1 LRRIQ1 MAST4 SYNE2 RP1 BBOF1	1.17e-08	196	97	8	6d02d494196e3f857d53eea46d9419690d43beca
ToppCell	LPS_IL1RA-Endothelial-Endothelial-FOXM1\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	MAP1B NSD2 CNTRL KIF20B ANLN SYNE2 DIAPH3 IQGAP3	1.31e-08	199	97	8	be2276c9a1994579ba1d2998b49bf549c1324d44
ToppCell	Control_saline-Endothelial-Endothelial-FOXM1\|Control_saline / Treatment groups by lineage, cell group, cell type	NSD2 CNTRL MCM4 KIF20B CCDC88A ANLN DIAPH3 IQGAP3	1.36e-08	200	97	8	9bbc7b5561151f6ff65f40b3226271def732e5d9
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NSD2 MCM4 KIF20B RTKN2 ANLN DIAPH3 IQGAP3	7.97e-08	166	97	7	2642544070564debe2deb2938d2c33997bf5ef02
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NSD2 KIF20B LMOD3 RTKN2 ANLN DIAPH3 IQGAP3	1.06e-07	173	97	7	a25459b8140b0dbcb73e3b4cc1407b679229f25c
ToppCell	droplet-Limb_Muscle-MUSCLE-30m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SYNE1 CNTRL MTSS1 GBP2 GVINP1 SYNE2 CAVIN2	1.28e-07	178	97	7	01dafd19de04eff459253eaa9a35debf8f3deedf
ToppCell	droplet-Marrow-nan-3m-Myeloid-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK8 CNTRL MTSS1 CHD9 CCDC88A ATP2B1 TOP2B	1.49e-07	182	97	7	f8c73baaaca145e2efc48f10f636feb79c8fc779
ToppCell	Control-Myeloid-cDC1\|Myeloid / Disease state, Lineage and Cell class	SIPA1L3 ANKRD20A2P ANKRD20A3P ANKRD20A8P BCR ANKRD20A4P ANKRD20A1	1.61e-07	184	97	7	c6affa0b12510363258f65e46bf2d47bf4a8e75f
ToppCell	COPD-Myeloid-cDC1\|World / Disease state, Lineage and Cell class	SIPA1L3 ANKRD20A2P ANKRD20A3P ANKRD20A8P BCR ANKRD20A4P ANKRD20A1	1.61e-07	184	97	7	42d7ce104cd7bcb83fbbbd0e7d3267ad07edfa94
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SH3RF1 RTKN2 LLGL2 RP1 DIAPH3 MYO16 PLCE1	1.67e-07	185	97	7	1c222f7285d6e3dae0354dc7e853ddc0ea55e63e
ToppCell	droplet-Marrow-nan-3m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK8 CNTRL CHD9 ZNF106 CCDC88A ATP2B1 TOP2B	1.67e-07	185	97	7	7adfa929930cfa795cbfbd9f1a0b439e08aa765d
ToppCell	IPF-Myeloid-cDC1\|World / Disease state, Lineage and Cell class	SIPA1L3 ANKRD20A2P ANKRD20A3P ANKRD20A8P BCR ANKRD20A4P ANKRD20A1	1.73e-07	186	97	7	962c2dada19185628ead77c32fcb07fa95114247
ToppCell	Epithelial-alveolar_epithelial_cell_type_1\|World / Lineage, Cell type, age group and donor	SH3RF1 RTKN2 LLGL2 RP1 DIAPH3 MYO16 PLCE1	1.73e-07	186	97	7	09d95daa3387a4814cffaa4b798cc2810c3759d0
ToppCell	IPF-Myeloid-cDC1\|Myeloid / Disease state, Lineage and Cell class	SIPA1L3 ANKRD20A2P ANKRD20A3P ANKRD20A8P BCR ANKRD20A4P ANKRD20A1	1.86e-07	188	97	7	47bb6caf84f70a1cda7d09803afdfd5182772e66
ToppCell	COPD-Multiplet-Multiplet\|World / Disease state, Lineage and Cell class	SYNE1 LRRIQ1 MAST4 SYNE2 DIAPH3 CAVIN2 SMAD3	1.86e-07	188	97	7	186fe1ea328c942910190a4240262c0d8642ea3b
ToppCell	IPF-Myeloid-cDC1\|IPF / Disease state, Lineage and Cell class	SIPA1L3 ANKRD20A2P ANKRD20A3P ANKRD20A8P BCR ANKRD20A4P ANKRD20A1	1.86e-07	188	97	7	2331a2bae1383820d598e93aa86c75b101069bac
ToppCell	pdx-Tumor_cells-T1\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	NSD2 KIF20B RTKN2 ANLN OTUD7A DIAPH3 IQGAP3	2.00e-07	190	97	7	d06ee5f89f1cec8db6897fe3b2a890a07cd3697b
ToppCell	COPD-Myeloid-cDC1\|Myeloid / Disease state, Lineage and Cell class	SIPA1L3 ANKRD20A2P ANKRD20A3P ANKRD20A8P BCR ANKRD20A4P ANKRD20A1	2.07e-07	191	97	7	3480e6d27dd4291765bbbb2acdb6a2e4f02c8085
ToppCell	COPD-Myeloid-cDC1\|COPD / Disease state, Lineage and Cell class	SIPA1L3 ANKRD20A2P ANKRD20A3P ANKRD20A8P BCR ANKRD20A4P ANKRD20A1	2.15e-07	192	97	7	bd3d00b094d92463b06023361a71240851a542b8
ToppCell	human_hepatoblastoma-Tumor_cells-T1\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	NSD2 KIF20B RTKN2 ANLN OTUD7A DIAPH3 IQGAP3	2.22e-07	193	97	7	4b9fa2a4424f8abe63fa7bee78db93dda04ab15f
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH3 INTU SYNE1 ANKRD18B LRRIQ1 RP1 BBOF1	2.30e-07	194	97	7	4a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_cycling\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	NSD2 MCM4 KIF20B RTKN2 ANLN DIAPH3 IQGAP3	2.47e-07	196	97	7	1d2e0b328eb822db7521b5f5724d4bd17c0bad5f
ToppCell	(11)_FOXN4+-(2)_GFP_FOXI1\|(11)_FOXN4+ / shred by cell type by condition	CNTRL KIF20B ZNF106 CCDC88A LRRIQ1 SYNE2 BOD1L1	2.64e-07	198	97	7	76d40b8c2f8399725b3a62ee2ae0896559cf91eb
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-FOXM1\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	NSD2 CNTRL KIF20B ANLN SYNE2 DIAPH3 IQGAP3	2.73e-07	199	97	7	98575fcce726589e93fbb4df1aab03e57cb56076
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-10w-Stem_cells-Neuroepithelial_cell\|10w / Sample Type, Dataset, Time_group, and Cell type.	MCM4 KIF20B RTKN2 ANLN SYNE2 DIAPH3 IQGAP3	2.83e-07	200	97	7	8f8b8c225cdc79baf16fe04be89bdb65e404a055
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-FOXM1\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	NSD2 CNTRL KIF20B CCDC88A ANLN DIAPH3 IQGAP3	2.83e-07	200	97	7	4cfe08878a6981bf7b3567f9e82192d8f060ddde
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-10w-Stem_cells\|10w / Sample Type, Dataset, Time_group, and Cell type.	MCM4 KIF20B RTKN2 ANLN SYNE2 DIAPH3 IQGAP3	2.83e-07	200	97	7	a1f48eca9efb4f3ec3c9ace20f8c9257dd72c4ed
ToppCell	H1299\|World / Cell line, Condition and Strain	NSD2 MCM4 RFC1 CCDC88A BOD1L1 MRTO4 RPL7A	2.83e-07	200	97	7	23f08d7cffacfced48785cd3ad230ecadb95713f
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-7\|TCGA-Brain / Sample_Type by Project: Shred V9	NSD2 ANKRD20A3P ANKRD20A8P KIF20B MAP3K4 RTKN2	5.38e-07	136	97	6	d94f0fbeb7b80d4cf0687d1924ebf8f9dd07358c
ToppCell	NS-moderate-d_07-13-Epithelial-FOXN4+\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DNAH3 INTU LRRIQ1 ANLN PLCE1 BBOF1	1.25e-06	157	97	6	410c9d74a2085179cfb39853cb6d330fa98c9c1b
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KIF20B RTKN2 ANLN DIAPH3 IQGAP3 ANKRD20A1	1.79e-06	167	97	6	50c29ea660bf07b890e4ac1a1985d0761d863dee
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KIF20B RTKN2 ANLN DIAPH3 IQGAP3 ANKRD20A1	1.85e-06	168	97	6	d35944fd9fea9934ce1e76b2b35d48e2300cca61
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NSD2 KIF20B RTKN2 ANLN DIAPH3 IQGAP3	1.91e-06	169	97	6	b253a4a50c06d36228fcd5d856c57202cbac158f
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NSD2 MCM4 RTKN2 ANLN DIAPH3 IQGAP3	1.91e-06	169	97	6	0bc8ef341ce307b19018d4ac8de0a4d04254209d
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NSD2 KIF20B RTKN2 ANLN DIAPH3 IQGAP3	2.27e-06	174	97	6	84da9faff088d05233183b425385beb054c92d1b
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NSD2 KIF20B RTKN2 ANLN DIAPH3 IQGAP3	2.27e-06	174	97	6	dbb4e1a6c3319ce40f81bfd2d1745a88a2cc412e
ToppCell	Control-Epithelial_cells-AT1\|Control / group, cell type (main and fine annotations)	SH3RF1 RTKN2 RP1 DIAPH3 MYO16 PLCE1	2.27e-06	174	97	6	548d7f2b958a2bfd2c95eb049ceaab55a559c77d
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_G2M\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NSD2 KIF20B RTKN2 ANLN DIAPH3 IQGAP3	2.34e-06	175	97	6	876cea684faf42ff3eb4623ad6d7a1fb1276ee02
ToppCell	Int-URO-Lymphocyte-T_NK-gdT\|Int-URO / Disease, Lineage and Cell Type	SYNE1 LEMD1 RTKN2 LLGL2 SYNE2 OTUD7A	2.42e-06	176	97	6	15016a73c953d8d3e7c32a05ead5e7261f9914ca
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	RTKN2 LLGL2 RP1 DIAPH3 MYO16 PLCE1	2.67e-06	179	97	6	4f6ca313b78aa93557937a046c44dcf8bcc9963c
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NSD2 MCM4 RTKN2 ANLN DIAPH3 IQGAP3	2.67e-06	179	97	6	88d44b04eb5c079531db663ed98ddb20b60feb9a
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NSD2 KIF20B RTKN2 ANLN DIAPH3 IQGAP3	2.76e-06	180	97	6	401df9cddcbca1eb8f0d2687bcacd98e95dc1493
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NSD2 MCM4 KIF20B ANLN DIAPH3 IQGAP3	2.76e-06	180	97	6	f8a15c13d85c1bbbf86ce49bb6f86c368ddf22df
ToppCell	PBMC-Control-Myeloid-Neutrophil-immature_Neutrophil\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	NSD2 MCM4 EMSY ANKRD20A4P ANLN VPS13A	3.13e-06	184	97	6	a8c6028d745aaa6ee7842259238694cb50ce0526
ToppCell	PBMC-Control-Myeloid-Neutrophil-immature_Neutrophil-Neu_4\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	NSD2 MCM4 EMSY ANKRD20A4P ANLN VPS13A	3.13e-06	184	97	6	081d045f3bc98a36f342de7d50f39c9a888dd7eb
ToppCell	Control-Myeloid_G-immature_Neutrophil\|Control / Disease group, lineage and cell class	NSD2 MCM4 EMSY ANKRD20A4P ANLN VPS13A	3.13e-06	184	97	6	45f873236f7e90fb78c8e291d3b5b92d121acec9
ToppCell	PBMC-Control-Myeloid-Neutrophil-immature_Neutrophil\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	NSD2 MCM4 EMSY ANKRD20A4P ANLN VPS13A	3.13e-06	184	97	6	84c20730cd92b9aaa50077d7b625e37e7f9e91d2
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT1-AT1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SH3RF1 RTKN2 LLGL2 DIAPH3 MYO16 PLCE1	3.13e-06	184	97	6	57c792e6e2fedba25d3350ffe649fd74750b579d
ToppCell	droplet-Marrow-nan-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK8 CNTRL CHD9 ZNF106 CCDC88A TOP2B	3.13e-06	184	97	6	1154a5ad7b8512272b7476f949ddac350910bfb7
ToppCell	PBMC-Control-Myeloid-Neutrophil-immature_Neutrophil-Neu_4\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	NSD2 MCM4 EMSY ANKRD20A4P ANLN VPS13A	3.13e-06	184	97	6	d31d4116d1d196633784863781fa45673607a421
ToppCell	Control-immature_Neutrophil-\|Control / Disease condition and Cell class	NSD2 MCM4 EMSY ANKRD20A4P ANLN VPS13A	3.13e-06	184	97	6	c4e8ba82a6aa76c46f05a71d5f1c7926555318cf
ToppCell	Control-immature_Neutrophil\|Control / Disease condition and Cell class	NSD2 MCM4 EMSY ANKRD20A4P ANLN VPS13A	3.13e-06	184	97	6	2fdae5c6b3eb2232881d933a8c1061fda3623016
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1-D122\|Adult / Lineage, Cell type, age group and donor	RTKN2 LLGL2 RP1 DIAPH3 MYO16 PLCE1	3.13e-06	184	97	6	561592edc3083fad41b91811151b442207c65dd9
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SH3RF1 RTKN2 LLGL2 DIAPH3 MYO16 PLCE1	3.13e-06	184	97	6	d7bd0f0c607bade67c99e9fb3578a570298bf926
ToppCell	droplet-Lung-18m-Hematologic-myeloid-classical_monocyte_proliferating-classical_monocyte_proliferating_l33-52\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NSD2 KIF20B RTKN2 ANLN DIAPH3 DEPDC7	3.23e-06	185	97	6	47c69500877b851c0c9744f5e1ef2ee0bff99168
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1-D175\|Adult / Lineage, Cell type, age group and donor	SH3RF1 SIPA1L3 RTKN2 LLGL2 CAVIN2 PLCE1	3.23e-06	185	97	6	32b4e68e551d435a732f253f6ad83408c759a642
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NSD2 KIF20B RTKN2 ANLN DIAPH3 IQGAP3	3.23e-06	185	97	6	30e041d6f6e310d64809e9d6d93cd30052972f3b
ToppCell	Control-Myeloid-cDC1\|Control / Disease state, Lineage and Cell class	SIPA1L3 ANKRD20A2P ANKRD20A3P ANKRD20A8P ANKRD20A4P ANKRD20A1	3.33e-06	186	97	6	b05c394aa3573ba855abc3066739ca193883b0c3
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NSD2 KIF20B RTKN2 ANLN DIAPH3 IQGAP3	3.43e-06	187	97	6	9351fa87b69a951af85b10bf91fe9b1cce8c0517
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NSD2 KIF20B RTKN2 ANLN DIAPH3 IQGAP3	3.43e-06	187	97	6	057569c9437219ecc396aa6e673b1178a2273837
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1\|Adult / Lineage, Cell type, age group and donor	SH3RF1 RTKN2 LLGL2 DIAPH3 MYO16 PLCE1	3.43e-06	187	97	6	77f78aec946bc6bd85c29aee9ca978ce49f853a3
ToppCell	Epithelial-Epithelial-D_(Ciliated)\|Epithelial / shred on cell class and cell subclass (v4)	DNAH3 SLF1 MAP1B SYNE1 LRRIQ1 BBOF1	3.54e-06	188	97	6	8f30535a32968a81a304315a49c0d90a77d36948
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MCM4 KIF20B RTKN2 ANLN DIAPH3 IQGAP3	3.65e-06	189	97	6	fd8834d1feb7f63911c5fa51efb1f679a8baddeb
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SH3RF1 RTKN2 LLGL2 RP1 DIAPH3 MYO16	3.76e-06	190	97	6	30b50d183d7649146eb1e79b47ba897355f1998a
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CNTRL KIF20B CCDC88A ANLN DIAPH3 IQGAP3	3.76e-06	190	97	6	cd37ccd30c27cf65eda0a9165f35b7672f5acaf6
ToppCell	H1299-infected\|H1299 / Cell line, Condition and Strain	NSD2 KIF20B CCDC88A VPS13A BOD1L1 MRTO4	4.00e-06	192	97	6	9cf8049bdc3e0f81ce69042beac72b08d8f38b4e
ToppCell	Severe_COVID-19-Myeloid-proliferating_Myeloid_cells\|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）	MCM4 KIF20B ANLN HADH DIAPH3 IQGAP3	4.12e-06	193	97	6	0d85025690c9cd545cba30abc38acbdd6a39b153
ToppCell	severe-low-quality_cells\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SYNE1 USP24 MAP3K4 RTKN2 SYNE2 VPS13A	4.12e-06	193	97	6	9337bc93e3904c7fc7c93c328518bcd6453b1e8c
ToppCell	3'_v3-blood-Lymphocytic_T_CD4-Tregs\|blood / Manually curated celltypes from each tissue	GBP2 KIF20B RTKN2 MAST4 SYNE2 NCK2	4.12e-06	193	97	6	2ffe44edf2b02d11a7c10513692eb697a10f911e
ToppCell	Bronchial_Biopsy-Epithelial-Ciliated_1\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	DNAH3 MAP1B SYNE1 LRRIQ1 RP1 BBOF1	4.12e-06	193	97	6	0b62a6ddd7c42efd9f39781971d1438501e1fa8d
ToppCell	BAL-Severe-Myeloid-Myeloid-proliferating_Myeloid_cells-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	MCM4 KIF20B ANLN HADH DIAPH3 IQGAP3	4.24e-06	194	97	6	193cc20fefbd795a4ad59e401a95af47d30603e7
ToppCell	PCW_13-14-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	DSP RTKN2 LRRIQ1 ANLN DIAPH3 IQGAP3	4.24e-06	194	97	6	c197e4acbff42a9f0410b6801c2bfcf6160aefc1
ToppCell	BAL-Severe-Myeloid-Myeloid-proliferating_Myeloid_cells\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	MCM4 KIF20B ANLN HADH DIAPH3 IQGAP3	4.24e-06	194	97	6	903ae11708b0cb24538c6982abd57fe6fa95b8d3
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SH3RF1 SIPA1L3 ARHGAP6 LLGL2 MAST4 SYNE2	4.24e-06	194	97	6	7002937e8903e037332a215d00fbc7c7843b33f2
ToppCell	BAL-Severe-Myeloid-Myeloid\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	MCM4 KIF20B ANLN HADH DIAPH3 IQGAP3	4.24e-06	194	97	6	58406502a8cbcc3037f79a1b6a683df408297ae5
ToppCell	droplet-Marrow-nan-3m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NSD2 CNTRL MTSS1 CHD9 KIF20B TOP2B	4.24e-06	194	97	6	8ef0b71fef5b84cfd04973f891215333e7035d1d
ToppCell	IPF-Multiplet-Multiplet\|IPF / Disease state, Lineage and Cell class	DNAH3 SYNE1 LRRIQ1 MAST4 SYNE2 RP1	4.37e-06	195	97	6	fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCell	Bronchial-NucSeq-Epithelial-Epi_alveolar-AT1\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	RTKN2 LLGL2 RP1 DIAPH3 MYO16 PLCE1	4.37e-06	195	97	6	a71ba5e4043e2d35a45a2c60a96b087e31832345
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SH3RF1 SIPA1L3 ARHGAP6 LLGL2 MAST4 RP1	4.37e-06	195	97	6	6477e6e7be5bd8eb99119a12ae16334ccddecd43
ToppCell	Children_(3_yrs)-Epithelial-club_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SH3RF1 ABCC5 MAST4 SYNE2 RP1 PLCE1	4.37e-06	195	97	6	dccc32fcf772e2504de7f663ef0a5bd8e23e92fc
ToppCell	IPF-Multiplet\|IPF / Disease state, Lineage and Cell class	DNAH3 SYNE1 LRRIQ1 MAST4 SYNE2 RP1	4.37e-06	195	97	6	eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MCM4 KIF20B RTKN2 ANLN DIAPH3 IQGAP3	4.37e-06	195	97	6	75759fd7f925725f0ecd07214afcca5aa2158f9e
ToppCell	nucseq-Epithelial\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SH3RF1 SYNE1 RTKN2 LLGL2 MAST4 MLPH	4.37e-06	195	97	6	9406866f99555198a9be311fbd65751b70f35446
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NSD2 KIF20B ANLN DIAPH3 IQGAP3 CAVIN2	4.50e-06	196	97	6	20383d576708b7e4bfce3e9fe40548cce496e3cb
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NSD2 KIF20B ANLN DIAPH3 IQGAP3 CAVIN2	4.50e-06	196	97	6	0644bd14a944b9c9759a295dfdd5e67a4775f20a
ToppCell	COPD-Endothelial-VE_Capillary_B\|Endothelial / Disease state, Lineage and Cell class	SH3RF1 ANKRD20A2P ANKRD20A3P ARHGAP6 MAST4 ANKRD20A4P	4.63e-06	197	97	6	30dbc05ea66892d2e18ff375ffa86d1db7bc4083
ToppCell	severe-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SYNE1 USP24 MAP3K4 RTKN2 SYNE2 VPS13A	4.63e-06	197	97	6	57ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH3 INTU SYNE1 LRRIQ1 SYNE2 RP1	4.63e-06	197	97	6	74a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NSD2 KIF20B ANLN DIAPH3 IQGAP3 CAVIN2	4.63e-06	197	97	6	a41420d4b6d502c2f594c054c7efbb5d4eac83ff
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_cycling\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	MCM4 KIF20B RTKN2 ANLN DIAPH3 IQGAP3	4.63e-06	197	97	6	8b616cde333bdbc0c591035ad9e4949155866245
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NSD2 KIF20B ANLN DIAPH3 IQGAP3 CAVIN2	4.63e-06	197	97	6	1c89d6836eed30c50c765f7dde9cc8ee15c363d2
ToppCell	critical-Epithelial-Ciliated\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	DNAH3 SYNE1 CNTRL LRRIQ1 RP1 BBOF1	4.77e-06	198	97	6	ee2c8385c0bf4ea9f5c9517b52cf131af3fbdd40
ToppCell	10x_3'_v3-bone_marrow_(10x_3'_v3)-myeloid-myeloid_granulocytic-granulocyte\|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	NSD2 MCM4 KIF20B CCDC88A ANLN IQGAP3	4.77e-06	198	97	6	2e669da80363163b806f23a645474d482797ae5d
ToppCell	3'_v3-bone_marrow-Hematopoietic_progenitors-Cycling_pre-Myeloid-1\|bone_marrow / Manually curated celltypes from each tissue	NSD2 MCM4 CCDC88A ANLN DIAPH3 IQGAP3	4.77e-06	198	97	6	5c92687b853ebb00960adbef6552f9d460bc6886
ToppCell	15-Airway-Mesenchymal-Mesenchyme_RSPO2+\|Airway / Age, Tissue, Lineage and Cell class	NSD2 KIF20B RTKN2 ANLN DIAPH3 IQGAP3	4.91e-06	199	97	6	5c8b847b794b3e88722f5b841f2539a27251106c
ToppCell	Non-neuronal-Dividing-IPC-IPC-div1-28\|World / Primary Cells by Cluster	CNTRL KIF20B RTKN2 ANLN DIAPH3 IQGAP3	4.91e-06	199	97	6	787688b68ae5d8768c0a24673ae07ab07616764a
Disease	Emery-Dreifuss muscular dystrophy (implicated_via_orthology)	SYNE1 LEMD1 SYNE2	5.92e-06	12	90	3	DOID:11726 (implicated_via_orthology)
Disease	prostate carcinoma	SH3RF1 SIPA1L3 PKD1L3 HIBADH EMSY ARHGAP6 MAST4 ANLN SYNE2 MLPH MYO16 SMAD2	1.68e-05	891	90	12	EFO_0001663
Disease	Autosomal dominant Emery-Dreifuss muscular dystrophy	SYNE1 SYNE2	5.50e-05	4	90	2	cv:CN293514
Disease	Colorectal Carcinoma	DNAH3 MAP1B SYNE1 ABCC5 HIVEP3 ZNF540 VPS13A MTRR SMAD2 SMAD3	5.63e-05	702	90	10	C0009402
Disease	Autosomal Recessive Emery-Dreifuss Muscular Dystrophy	SYNE1 SYNE2	9.15e-05	5	90	2	C1450051
Disease	Cerebellar Ataxia	SYNE1 RFC1	9.15e-05	5	90	2	C0007758
Disease	Autosomal Dominant Emery-Dreifuss Muscular Dystrophy (disorder)	SYNE1 SYNE2	9.15e-05	5	90	2	C0410190
Disease	Emery-Dreifuss muscular dystrophy	SYNE1 SYNE2	1.37e-04	6	90	2	cv:C0410189
Disease	Muscular Dystrophy, Emery-Dreifuss	SYNE1 SYNE2	1.37e-04	6	90	2	C0410189
Disease	Dengue Hemorrhagic Fever	RP1 PLCE1	1.91e-04	7	90	2	EFO_0004227
Disease	CHARGE syndrome (implicated_via_orthology)	CHD9 CHD6	1.91e-04	7	90	2	DOID:0050834 (implicated_via_orthology)
Disease	Loeys-Dietz Syndrome	SMAD2 SMAD3	1.91e-04	7	90	2	C2697932
Disease	X-Linked Emery-Dreifuss Muscular Dystrophy	SYNE1 SYNE2	1.91e-04	7	90	2	C0751337
Disease	vital capacity	DSP SYNE1 PKD1L3 HIBADH ZNF106 LLGL2 LRRIQ1 RPRD2 DIAPH3 MYO16 SMAD3 PLCE1	3.71e-04	1236	90	12	EFO_0004312
Disease	L2 Acute Lymphoblastic Leukemia	NSD2 BCR MTRR	4.85e-04	50	90	3	C0023453
Disease	Childhood Acute Lymphoblastic Leukemia	NSD2 BCR MTRR	5.44e-04	52	90	3	C0023452
Disease	Precursor Cell Lymphoblastic Leukemia Lymphoma	NSD2 BCR MTRR	8.69e-04	61	90	3	C1961102
Disease	basophil count, eosinophil count	EMSY HIVEP3 PLCL2 MEIOSIN SMAD3	8.72e-04	241	90	5	EFO_0004842, EFO_0005090
Disease	delta-6 desaturase measurement	MAST4 DIAPH3	9.41e-04	15	90	2	EFO_0007765
Disease	rhinitis	EMSY SMAD3	1.21e-03	17	90	2	EFO_0008521
Disease	asthma, age at onset	EMSY GSDMA SMAD3	1.30e-03	70	90	3	EFO_0004847, MONDO_0004979
Disease	eosinophil count	DNAH3 SIPA1L3 ABCC5 MCM4 EMSY HIVEP3 PLCL2 GSDMA MYO16 SMAD2 NCK2 SMAD3	1.86e-03	1488	90	12	EFO_0004842
Disease	Left Ventricle Remodeling	SMAD2 SMAD3	1.86e-03	21	90	2	C0600520
Disease	Ventricular Remodeling	SMAD2 SMAD3	1.86e-03	21	90	2	C0600519
Disease	blood pressure	SYNE1 MYO16	2.04e-03	22	90	2	EFO_0004325
Disease	Lynch syndrome (is_implicated_in)	SMAD2 SMAD3	2.43e-03	24	90	2	DOID:3883 (is_implicated_in)
Disease	obsolete_red blood cell distribution width	DOCK8 ABCC5 RFC1 MAST4 ANLN SYNE2 PLCL2 VPS13A RP1 MYO16 BBOF1	2.63e-03	1347	90	11	EFO_0005192
Disease	osteoarthritis, hip	PLCL2 RPRD2 SMAD3	2.83e-03	92	90	3	EFO_1000786

Protein segments in the cluster

Peptide	Gene	Start	Entry
KKILKKEKSDVGSSD	ANKRD20A1	256	Q5TYW2
SGKKDLVLEEKSKKL	ANKRD20A1	771	Q5TYW2
GLDKELKKLKKAVAT	CNTRL	971	Q7Z7A1
LKKLKKAVATSDKLA	CNTRL	976	Q7Z7A1
LLDKKSLKISGIKDF	EIF3B	456	P55884
SGKKDLVLEEKSKKL	ANKRD20A8P	771	Q5CZ79
KLVSKDGITDKKLKE	ADGRB1	1116	O14514
KGSKATERLKKKLSE	BCR	806	P11274
KKILKKEKSDVGSSD	ANKRD20A4P	256	Q4UJ75
SGKKDFVLEEKSKKL	ANKRD20A4P	771	Q4UJ75
LEKSRKLALTVKGKE	GVINP1	1866	Q7Z2Y8
SLLSSLSKLLGKKKE	GSDMA	281	Q96QA5
KDNTASLKKKELTLK	ANKRD18B	866	A2A2Z9
DIKKLTKKLKGELAK	AKAP11	1116	Q9UKA4
KSGEKKVDALLKEKR	CLIP2	861	Q9UDT6
EDSKLSAKEKKKLLG	DEPDC7	481	Q96QD5
KKSKSFSKLLELVLL	DIAPH3	831	Q9NSV4
GKSKGKDTKKLIKTD	BBOF1	11	Q8ND07
REKLKISKINKGEKS	CC2D2B	51	Q6DHV5
KKEKSVLQGKLTKLA	ATP2B1	356	P20020
TKKKIDILLKAVGDT	ATG12	51	O94817
EKDILKAISKKKGSI	CCDC113	151	Q9H0I3
KAISKKKGSILATQK	CCDC113	156	Q9H0I3
ERESSILAKLKKKKG	AP2A2	606	O94973
KTKSTSKGIEILLEK	PUM3	631	Q15397
GNIILSTEKSKKLKK	LEMD1	76	Q68G75
KKILKKEKSDVGSSD	ANKRD20A2P	256	Q5SQ80
SGKKDLVLEEKSKKL	ANKRD20A2P	771	Q5SQ80
LAEALKKLILSKGKT	MCM4	801	P33991
LGKALKKDLKEKTKT	MAP1B	2231	P46821
KVSAKLKLKLTALEG	LLGL2	826	Q6P1M3
SLKKGSLVKNLKDTL	NCK2	61	O43639
KKISKLDPKKLALDT	LMOD3	211	Q0VAK6
ELSKLLKKKGTSTFL	MYO16	991	Q9Y6X6
SKKGIEESLRKVAKK	HADH	66	Q16836
SGLDKKKKTSKSKAI	ANLN	891	Q9NQW6
VLLKIKADTKKKGAT	MTRR	341	Q9UBK8
NDTRLLKKLKKGKIT	DDX55	556	Q8NHQ9
QLKKGLELLKASFKK	CCDC88A	736	Q3V6T2
SSDTLKLQKKAKKGR	MTSS1	141	O43312
TLSSEEKGKKTKKKT	NSD2	1211	O96028
KAELAKTKGELIKTK	KIF20B	721	Q96Q89
ELSLKLRKGTDKKSK	GBP2	201	P32456
DEEKSKLLAKLLKSK	GGA3	171	Q9NZ52
KLGSFSKTLGIKLKK	OTUD7A	516	Q8TE49
IALKTGTKKLTKKEI	MEIOSIN	91	C9JSJ3
LDKQKGLKSLSKEKR	IQGAP3	936	Q86VI3
SKTSRKSLLKSEKEK	LRRIQ1	1526	Q96JM4
SKKLKKKIDSTVRLA	LRRIQ1	1566	Q96JM4
ESGTLLKVTKKKSTL	INTU	751	Q9ULD6
ILSAILKKKSEKGRS	OR5AC1	221	P0C628
KSLRKKLDSLGKEKN	ARHGAP6	256	O43182
KILKLKNIKEKSLGE	ABCC5	261	O15440
KSLLEEKLVLKSKSK	BOD1L1	901	Q8NFC6
LKISKEDSKILKKAR	FRG1	221	Q14331
KKILKKEKSDVGSSD	ANKRD20A3P	256	Q5VUR7
SGKKDLVLEEKSKKL	ANKRD20A3P	771	Q5VUR7
SKLKEKTKIGKLIIT	CHD9	586	Q3L8U1
LSESSKLKLKSPRKK	C2CD2	496	Q9Y426
SDGGKSKEKIEKLKL	DOCK8	371	Q8NF50
KKILGDLKFLESLKT	DNAH3	2831	Q8TD57
KKKIVKTSATALGDK	ELOA	446	Q14241
KKKGKRKSETTVESL	CHD6	196	Q8TD26
IDKTTLDKLLKGKKS	DSP	1986	P15924
SVLISGDIKDRLKKK	FAM98B	96	Q52LJ0
KKKISGKVTKSLSAS	MAST4	1076	O15021
LTKEKKDLLGELSKV	EMSY	41	Q7Z589
IKRSSLKKVDSLKKA	CAVIN2	231	O95810
KKPAKSILKSSKLSD	RPRD2	851	Q5VT52
KQILDSDKSKLKKSL	C18orf63	666	Q68DL7
LEALKGKIKKESSKR	MLPH	36	Q9BV36
RDKKVSLTKTAKKGL	MRTO4	6	Q9UKD2
KRKGDKVKASAILSK	RP1	871	P56715
LLLKLTSVSKKKDRE	MAP3K4	231	Q9Y6R4
SKALKELKLPSKDKD	FER1L6	416	Q2WGJ9
KLKTSISKATGKKIS	RTKN2	196	Q8IZC4
KDLLKKFQTKKTGLS	GTF2F1	471	P35269
LSKKKDRKAAKTLGI	TAAR3P	246	Q9P1P4
KLLKKKKGDLDTAAV	TOP2B	1256	Q02880
KLAKDLTTILTKLKA	SYNE1	5436	Q8NF91
LKSKRSTEKKGKFTL	SYNE2	2361	Q8WXH0
KKKGISFASELKKLT	PLCE1	2246	Q9P212
AKLEKAKAKELATKL	RPL7A	251	P62424
KTKSDEETLKAKKGI	RFC1	26	P35251
KESKKESSLKKSRIL	TAF1L	546	Q8IZX4
KESSLKKSRILLGKT	TAF1	531	P21675
KKTGKKKEKDLTSDR	IQCA1L	471	A6NCM1
LKGKILIKAKKLSSN	PLCL2	561	Q9UPR0
RTLKKKKLFKLTGDI	PKD1L3	1271	Q7Z443
LISLTSKKKEKTKAR	SIPA1L3	846	O60292
DSKKEKKGLLKLLSG	SH3RF1	711	Q7Z6J0
KKVKKGSLLIDSSTI	HIBADH	121	P31937
KLIKLLGFSESEKKS	NLRP9	291	Q7RTR0
KESIIEKSKTLRLKG	ZNF540	101	Q8NDQ6
DKGDVIKKLALKLST	VPS13A	1031	Q96RL7
KSLVKKLKKTGRLDE	SMAD2	46	Q15796
KSLVKKLKKTGQLDE	SMAD3	36	P84022
SELTKKTKKGLKTKG	HIVEP3	626	Q5T1R4
SLLESKGKVKTKKLQ	TTC5	276	Q8N0Z6
LLSDISKGKKLKKTV	WIPF1	36	O43516
SSLKKLKKKSEGELS	SLF1	771	Q9BQI6
TEKLKKSLKVKTRSG	ZNF839	121	A8K0R7
RLSILTKLVKKGEKK	USP24	2091	Q9UPU5
LTSAETRGSKKKKKL	ZNF106	1341	Q9H2Y7
KKGTIVKKLLLTVDT	HECTD3	286	Q5T447