Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
MousePhenoabsent erythrocytes

EP400 MIDEAS

6.20e-056292MP:0000215
DomainDUF4599

SPATA31D4 SPATA31D1 SPATA31D3

1.09e-0612333PF15371
DomainDUF4599

SPATA31D4 SPATA31D1 SPATA31D3

1.09e-0612333IPR027970
DomainMAM_1

TMPRSS15 NPNT

3.58e-0416332PS00740
DomainMAM

TMPRSS15 NPNT

4.05e-0417332SM00137
DomainMAM

TMPRSS15 NPNT

4.55e-0418332PF00629
DomainMAM_dom

TMPRSS15 NPNT

4.55e-0418332IPR000998
DomainMAM_2

TMPRSS15 NPNT

4.55e-0418332PS50060
DomainSH3_2

SHANK1 ARHGEF5 SH3D19

4.65e-0486333IPR011511
DomainSH3_2

SHANK1 ARHGEF5 SH3D19

4.65e-0486333PF07653
Domain-

CUX2 POU5F2

1.03e-03273321.10.260.40
DomainLambda_DNA-bd_dom

CUX2 POU5F2

1.19e-0329332IPR010982
DomainMYB_LIKE

EP400 MIDEAS

2.05e-0338332PS50090
DomainHomeodomain-like

CUX2 EP400 MIDEAS POU5F2

2.67e-03332334IPR009057
DomainSANT

EP400 MIDEAS

3.52e-0350332SM00717
DomainSANT/Myb

EP400 MIDEAS

3.80e-0352332IPR001005
DomainTPR_8

TANC2 UTY

3.94e-0353332PF13181
Domain-

TANC2 HELZ UTY

5.73e-032073331.25.40.10
DomainSH3

SHANK1 ARHGEF5 SH3D19

6.45e-03216333PS50002
DomainSH3

SHANK1 ARHGEF5 SH3D19

6.45e-03216333SM00326
DomainSH3_domain

SHANK1 ARHGEF5 SH3D19

6.78e-03220333IPR001452
DomainTPR-like_helical_dom

TANC2 HELZ UTY

7.94e-03233333IPR011990
DomainSH3_9

ARHGEF5 SH3D19

8.36e-0378332PF14604
PathwayREACTOME_FORMATION_OF_SENESCENCE_ASSOCIATED_HETEROCHROMATIN_FOCI_SAHF

EP400 RB1

1.42e-0415172MM14902
PathwayREACTOME_FORMATION_OF_SENESCENCE_ASSOCIATED_HETEROCHROMATIN_FOCI_SAHF

EP400 RB1

1.84e-0417172M27189
Pubmed

Gene expression of Sh3d19, a novel adaptor protein with five Src homology 3 domains, in anagen mouse hair follicles.

HELZ SH3D19

2.95e-06335212615363
Pubmed

A human MAP kinase interactome.

SHANK1 USP53 HELZ MIDEAS KIF26B SH3D19

8.31e-0648635620936779
Pubmed

VHL loss actuates a HIF-independent senescence programme mediated by Rb and p400.

EP400 RB1

9.82e-06535218297059
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

TANC2 USP53 HELZ KIF26B ARHGEF5 DENND4C SH3D19

2.04e-0586135736931259
Pubmed

Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.

GSE1 EP400 MIDEAS

8.12e-058335328794006
Pubmed

Rb regulates fate choice and lineage commitment in vivo.

RB1 PRDM16

1.17e-041635220686481
Pubmed

Kif26b, a kinesin family gene, regulates adhesion of the embryonic kidney mesenchyme.

KIF26B NPNT

1.17e-041635220439720
Pubmed

Cdkn1c Boosts the Development of Brown Adipose Tissue in a Murine Model of Silver Russell Syndrome.

RB1 PRDM16

1.33e-041735226963625
Pubmed

PRDM16 regulates a temporal transcriptional program to promote progression of cortical neural progenitors.

CUX2 PRDM16

1.66e-041935233597191
Pubmed

Interaction network of human early embryonic transcription factors.

GSE1 EP400 MIDEAS PRDM16

4.17e-0435135438297188
Pubmed

Corticothalamic Projection Neuron Development beyond Subtype Specification: Fog2 and Intersectional Controls Regulate Intraclass Neuronal Diversity.

CACNA1E GSE1

4.49e-043135227321927
Pubmed

A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.

TANC2 CLCN5 NHSL2 DENND4C SH3D19

7.23e-0471935535337019
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

TANC2 HELZ GSE1 EP400 RB1 PRDM16

7.88e-04111635631753913
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

USP53 CUX2 EP400 ARHGEF5

8.91e-0443035435044719
Pubmed

Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes.

GSE1 MIDEAS

9.48e-044535221258344
Cytoband9q21.32

SPATA31D4 SPATA31D1 SPATA31D3

3.90e-07193539q21.32
Cytoband5q15

ELL2 POU5F2

4.32e-04403525q15
CytobandEnsembl 112 genes in cytogenetic band chr9q21

SPATA31D4 SPATA31D1 SPATA31D3

4.74e-04199353chr9q21
CytobandEnsembl 112 genes in cytogenetic band chr5q15

ELL2 POU5F2

9.40e-0459352chr5q15
CoexpressionAtlasFacebaseRNAseq_e10.5_Olfactory Pit_top-relative-expression-ranked_1000

SHANK1 CUX2 ELL2 GSE1 RB1 PRDM16 KIF26B UTY NPNT

1.75e-05984349Facebase_RNAseq_e10.5_Olfactory Pit_1000
ToppCell10x3'2.3-week_17-19-Myeloid_DC-DC-pDC|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

PCED1B CUX2 CLNK CLCN5 KIF26B

3.83e-07191355faf4de97003a938a243b0101456913c2b0e1804f
ToppCellIPF-Stromal-Myofibroblast|Stromal / Disease state, Lineage and Cell class

TANC2 GSE1 KIF26B SH3D19 NPNT

4.46e-07197355f304d42fc4936fe20996e07c8dccc698a6e5e5ef
ToppCellmetastatic_Brain-Myeloid_cells-CD207+CD1a+_LCs|Myeloid_cells / Location, Cell class and cell subclass

CLNK KIF26B ARHGEF5 NPNT

9.84e-0617235438d17e769fe8eac8b57b820490d4ddd969243ee7
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TANC2 CLNK PRDM16 NPNT

1.28e-05184354ab2f06906fc7a9931dfa0864ef506832b07fb93e
ToppCellpdx-Tumor_cells-T0|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

CUX2 ELL2 GSE1 PRDM16

1.31e-051853541d874608aa2062024323512f68889219471b2f00
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TANC2 CLNK PRDM16 NPNT

1.34e-05186354e83718fabb057100835d3357df407f283d23fe16
ToppCell10x5'v1-week_14-16-Myeloid_DC-DC-pDC|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

PCED1B CUX2 CLNK CLCN5

1.37e-05187354bf64a6ef5062ec9a0f7095e8c97ce66bfc3bf179
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TANC2 CLNK PRDM16 NPNT

1.40e-051883544bdf8d49af0e9da349b16e3f012e1b0eec04cc4f
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 USP53 CLCN5 DENND4C

1.43e-05189354e059be2965cca70ff5576df055d0af1775b76e00
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 PRDM16 KIF26B MTMR10

1.43e-051893548ff3c3232eff9de4b5c9b22ecb82bc509d773f58
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 PRDM16 KIF26B MTMR10

1.46e-051903544836ea19308d2a96694f12ab0653b7ce7b101d2f
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

USP53 NHSL2 SH3D19 NPNT

1.49e-051913546688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCellCOVID-19-Fibroblasts-Alveolar_FB|COVID-19 / group, cell type (main and fine annotations)

USP53 NHSL2 KIF26B SH3D19

1.61e-05195354603050beeb33c331d4b2e3fa46cae3f3e0e4bdc7
ToppCellCOVID-19-Fibroblasts|COVID-19 / group, cell type (main and fine annotations)

USP53 NHSL2 KIF26B SH3D19

1.68e-05197354fb847f2277609c31fffcdf49517243ce0684facf
ToppCellParenchymal-10x3prime_v2-Immune_Myeloid-Dendritic_cell-DC_plasmacytoid|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

CUX2 EP400 POU5F2

1.58e-041343530e3f37ef041b751ed45060b5ce39385a2731370b
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CLNK PRDM16 KIF26B

1.79e-04140353e64f6aa57bc069cfe970089bd1c298433bfaf771
ToppCellControl-Myeloid-Dendritic_cells|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CUX2 CLNK CLCN5

1.91e-04143353bb8d4c335682d1a6798bed0de8bb0603054a4944
ToppCellControl-Myeloid-Dendritic_cells-pDC|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CUX2 CLNK CLCN5

1.99e-04145353bab85a72142b6257f7d424e5301f65b6dcdf745d
ToppCell390C-Lymphocytic-NK_cells-NK_cell_D2|390C / Donor, Lineage, Cell class and subclass (all cells)

NPIPB15 POU5F2 MTMR10

1.99e-041453533a34c25ff77cd33fdca84742097cc7484066ebc4
ToppCell390C-Lymphocytic-NK_cells-NK_cell_D2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

NPIPB15 POU5F2 MTMR10

2.29e-04152353595afcfa8b161e291fcaf2afc7336bac9b6fae0f
ToppCell10x5'-Liver-Lymphocytic_T_CD4/8-lo-Trm_Tgd|Liver / Manually curated celltypes from each tissue

PCED1B CLNK POU5F2

2.38e-04154353c6308074468235c88ef4ea43ab155d9f86cbf261
ToppCellfacs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l1-41|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SHANK1 CLCN5 NPNT

2.56e-041583536d2709b387945c015faa223c20d22b52a4082140
ToppCellCOVID-19_Convalescent-cDC-|COVID-19_Convalescent / Disease condition and Cell class

CLNK GLB1L3 FIGNL2

3.23e-04171353fb5fae8b3adafcbb7c5618d887966b418355ed4d
ToppCellICU-SEP-Myeloid-pDC|ICU-SEP / Disease, Lineage and Cell Type

SHANK1 CUX2 KIF26B

3.23e-0417135372c448a0dc4c569bd6b465f9aa395f38034e7ea6
ToppCellCOVID-19_Convalescent-cDC|COVID-19_Convalescent / Disease condition and Cell class

CLNK GLB1L3 FIGNL2

3.23e-041713539ccaa9f1629818b0f63a5d930ee78c01e04cd98d
ToppCellfacs-Marrow-T-cells-24m-Myeloid-CD4+_macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1E SH3D19 SLC49A4

3.34e-04173353ca3d2a9562734f76127e3e7d54c10b63e95141bb
ToppCellfacs-Marrow-T-cells-24m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1E SH3D19 SLC49A4

3.34e-0417335319a9e10885173d7712996be8660a3a5a7a9aa39f
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PCED1B CUX2 NHSL2

3.40e-041743539cc7251661ea2b1565eef1dfb8cf6dec3ade13d4
ToppCellnormal_Lymph_Node-B_lymphocytes-GrB-secreting_B_cells|normal_Lymph_Node / Location, Cell class and cell subclass

CUX2 ZNF843 CLCN5

3.45e-0417535329fbdfe1d3bfcb063be2bced0128a33176c5b78f
ToppCellfacs-Marrow-T_cells-18m-Myeloid-CD4+_macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1E CLCN5 SLC49A4

3.51e-0417635374f851a398c7562dd713bc0d8d488c0037243112
ToppCellB_cells-pDCs|B_cells / Immune cells in Kidney/Urine in Lupus Nephritis

CUX2 CLCN5 SH3D19

3.51e-04176353ce757de9e09a225f3f96433f103f43619b0e0dda
ToppCellCV-Severe-7|CV / Virus stimulation, Condition and Cluster

CLCN5 POU5F2 UTY

3.51e-041763533de0c7d77210049e5616db21eed1490a17a5ec2d
ToppCellfacs-Marrow-T_cells-18m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1E CLCN5 SLC49A4

3.51e-0417635331b5459a978d5cdde0af03a77401e0464d8c95ba
ToppCellLPS-IL1RA+antiTNF|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

UTY SH3D19 NPNT

3.57e-04177353b7fee75de7e96924af488a5baa2334711889ae7c
ToppCell10x3'2.3-week_12-13-Myeloid_DC-DC-pDC|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

PCED1B CLNK GLB1L3

3.57e-04177353e36c2005be74ee8ff03c2052504cb496faf86009
ToppCellCV-Severe-7|Severe / Virus stimulation, Condition and Cluster

CLCN5 POU5F2 UTY

3.57e-0417735382fdd6185b368f54f03de389427cbe3071d21a99
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-Myeloid-Mast_cell|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CLNK PLAAT5 FIGNL2

3.63e-04178353c6704fcd21a9d2fe45679a1d998f04213b3bf224
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

USP53 CLCN5 PRDM16

3.63e-041783534df6218b20c2f076c22346d23260964cc0d73e65
ToppCellCOVID-19-Heart-VSMC|Heart / Disease (COVID-19 only), tissue and cell type

ELL2 PRDM16 NPNT

3.69e-04179353a69ad6912b5c10bb9f9d800f724c792341e9bab1
ToppCellLPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TANC2 CLNK PRDM16

3.69e-04179353fd2cbee532e7b44113410dca82aec7db1a7fb69f
ToppCellfacs-Marrow-B-cells-3m-Myeloid-CD4+_macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1E CLCN5 SLC49A4

3.75e-04180353bf8d13d4db1af55b8c9fe16aaccf8743e000e005
ToppCellfacs-Marrow-B-cells-3m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1E CLCN5 SLC49A4

3.75e-04180353839defb40f7cfb2711e9025194de636533f51bcd
ToppCellfacs-Marrow-B-cells-3m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1E CLCN5 SLC49A4

3.75e-0418035382965ed1b72a1873c24dd4553d39681596057316
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 CLCN5 NPNT

4.00e-04184353d33de57876817050b294f2ecb0a4eb0634cfa7f0
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4_RORB_CACNG5|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

USP53 CUX2 NPNT

4.00e-04184353658f2e522055e88c92bc482a845c40f8f5f1a8e3
ToppCelldroplet-Spleen-nan-3m-Lymphocytic-plasma_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1E ELL2 NPNT

4.06e-04185353ff95a45b7cb782961bb8f008b6b507af2d4cb8b7
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 CLNK PRDM16

4.06e-041853533d73b3e0bceb192257e5cfbe64b7ccb379b6e22d
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

USP53 CLCN5 PRDM16

4.19e-041873537ea8731288e2a99f45e3958590ee1d76f49ae888
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 PRDM16 SH3D19

4.19e-0418735377886f99c229610abd28c4c370d2c7d1536c9782
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 PRDM16 MTMR10

4.19e-04187353f6217d0dd425eac76900b44a4e48f45475f3ac36
ToppCellLPS-antiTNF-Epithelial_alveolar|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CLNK PRDM16 NPNT

4.19e-04187353201ff693e4756ee3e44762885b3a303a77eb535b
ToppCellControl-Fibroblasts-Alveolar_FB|Control / group, cell type (main and fine annotations)

USP53 NHSL2 SH3D19

4.19e-0418735392d468dde81125d51daf7abd4703741abe1ab91c
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 PRDM16 MTMR10

4.19e-04187353e3095455d2f255854f339f6b05fa87852af0700f
ToppCellLA-13._Vascular_Smooth_Muscle|LA / Chamber and Cluster_Paper

PCED1B PRDM16 NPNT

4.26e-0418835334e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

USP53 CLCN5 PRDM16

4.26e-041883533cee9916399e2e7580cecbcbb27424a71e7e7ac0
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

USP53 CLCN5 PRDM16

4.33e-04189353f51cdc9a47371cab8ed9ae63a6f14da07ede446c
ToppCellrenal_medulla_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

PRDM16 UTY MTMR10

4.33e-04189353830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCellrenal_cortex_nuclei-Adult_normal_reference|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

USP53 ELL2 UTY

4.33e-04189353a48df46274d51e84ffb40264646de7346104efb9
ToppCellControl-Myeloid-Macrophage_Alveolar|Control / Disease state, Lineage and Cell class

PCED1B TANC2 DENND4C

4.33e-04189353937e876122bc4b94372a4104e9c1a9068c232018
ToppCellCOPD-Myeloid-Macrophage_Alveolar|Myeloid / Disease state, Lineage and Cell class

PCED1B TANC2 DENND4C

4.39e-041903539fc763d65470ba8858b973689c4d4358faab7dd3
ToppCellMS-pDC|MS / Condition, Cell_class and T cell subcluster

CUX2 CLCN5 KIF26B

4.39e-04190353f41d7ab7d7fbcd73fddb6c3533c6a3e642e3d07f
ToppCell10x3'2.3-week_17-19-Myeloid_DC|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

CUX2 CLNK KIF26B

4.39e-041903531687e133a88c3d036a33a4f8aeefe320a4f02c39
ToppCell10x3'2.3-week_17-19-Myeloid_DC-DC|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

CUX2 CLNK KIF26B

4.39e-041903533cfc2646ba25b4bd8bb443cc1f46e18a270a1969
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 PRDM16 MTMR10

4.39e-04190353b7f8c2bb9459f1d7c1690069dd5a25a81a57cc84
ToppCellCOVID-19-Heart-CM_4|Heart / Disease (COVID-19 only), tissue and cell type

ELL2 PRDM16 SLC49A4

4.39e-041903533729648a17093b438398b82e32bbccc3af7b8c5d
ToppCellMS-pDC-|MS / Condition, Cell_class and T cell subcluster

CUX2 CLCN5 KIF26B

4.39e-04190353f56ec302d556ace4f7609017a35c311cf43aa8a5
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Degenerative_Medullary_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

USP53 CLCN5 PRDM16

4.46e-04191353f631749ef1f2270133664cf5eb4cf545a8482bd3
ToppCellControl-Myeloid-Macrophage_Alveolar|Myeloid / Disease state, Lineage and Cell class

PCED1B TANC2 DENND4C

4.46e-04191353a7bb8aba9c59c037d995a77928cc7b4d5cbb82b9
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

USP53 NHSL2 SH3D19

4.53e-0419235399ce9e3c4c50cf64ebb62145f2b5420efa0db309
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 CLNK PRDM16

4.53e-04192353f7e7491426bbd6ed29a465b58bf67acb93dbb90a
ToppCellhuman_hepatoblastoma-Tumor_cells|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)

CUX2 ELL2 SH3D19

4.60e-04193353503a979328c68b096680b71359a26f02fafdff35
ToppCellCTRL-Myeloid-Alveolar_Macrophage|Myeloid / Disease state, Lineage and Cell class

PCED1B TANC2 DENND4C

4.60e-0419335380871d963c23a6befe58e5e60b7f7d1a1b227ce2
ToppCellAdult-Immune-alveolar_macrophage_(MARCO_positive)-D122|Adult / Lineage, Cell type, age group and donor

PCED1B UTY DENND4C

4.60e-04193353cc1b6d3bf56e4a88f6fe23dd036a83cf5538c958
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

USP53 NHSL2 SH3D19

4.60e-0419335399525545552b371c86b18b6ea6f4897dc6e9a9ec
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

USP53 NHSL2 SH3D19

4.60e-04193353b3ad5ff480d99217f36cc7471e5a96a519ddb409
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

USP53 NHSL2 SH3D19

4.67e-04194353e93de9428c986b8943fc169258847c650cfab0e5
ToppCell10x5'-bone_marrow-Myeloid_Dendritic|bone_marrow / Manually curated celltypes from each tissue

CUX2 CLNK CLCN5

4.67e-04194353768271ae45ff9f6aa3cd9b0ed15fa3caaa68a7b0
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell|Adult / Lineage, Cell type, age group and donor

USP53 NHSL2 SH3D19

4.74e-0419535361c9e09fc84d1012e472185d70ad0a06cee30d6e
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D122|Adult / Lineage, Cell type, age group and donor

USP53 NHSL2 SH3D19

4.74e-04195353aa0add081881d349099d12efca5cdee098038d4e
ToppCellCOVID-19-kidney-TAL|kidney / Disease (COVID-19 only), tissue and cell type

TANC2 CLCN5 PRDM16

4.81e-0419635304f5eb206ed3016a737609a3ebac0c1fcabb94ef
ToppCellChildren_(3_yrs)-Mesenchymal|Children_(3_yrs) / Lineage, Cell type, age group and donor

USP53 NHSL2 SH3D19

4.81e-04196353bc94909f9b2dc08a59eef1914148b69720569c8f
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

USP53 SH3D19 NPNT

4.81e-04196353cecf82cd5e0a3835d655f5e7478578674a63ce25
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

USP53 SH3D19 NPNT

4.81e-041963539737a5f006d37b549f281e1863aca558e1e4dc99
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

USP53 SH3D19 NPNT

4.88e-0419735394a9603cbd3516fbcce871909693b88f20d41713
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

TANC2 CLNK NPNT

4.88e-041973531485933986921ff45669d9b7501c8d17050b3e97
ToppCellTransverse-(5)_Dendritic_cell-(53)_Lymphoid_DC|Transverse / shred on region, Cell_type, and subtype

TANC2 CLCN5 MTMR10

4.88e-0419735315b87fd3906d7388c271d30d0c64b1bcc490801c
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

USP53 SH3D19 NPNT

4.88e-0419735313896ec65ccda0b928c91d41112dc01b480036b7
ToppCellTransverse-Dendritic_cell-Lymphoid_DC|Transverse / Region, Cell class and subclass

TANC2 CLCN5 MTMR10

4.88e-04197353a58af0ea82f76f2a7abac1f62629ff20d552fc63
ToppCellCOVID-19-lung-Fibroblast|lung / Disease (COVID-19 only), tissue and cell type

USP53 NHSL2 KIF26B

4.95e-04198353df3de77216f5c5d6141ec44d01c56b942f611838
ToppCelldistal-1-Hematologic-EREG+_Dendritic|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ELL2 RB1 NHSL2

5.03e-0419935315249f2f48b1e99d9d062835fd4c705a159e4abb
ToppCellParenchymal-NucSeq-Epithelial-Epi_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TANC2 PRDM16 NPNT

5.03e-041993538587bd98de7767a575088afbea07a1feb4516b9b
ToppCell343B-Fibroblasts-Fibroblast-G|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

USP53 SH3D19 NPNT

5.03e-04199353212e89d097753790061310373a1fafba773488b6
ToppCell343B-Fibroblasts-Fibroblast-G-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

USP53 SH3D19 NPNT

5.03e-0419935314b676aa289c0578a37be32cec3ea285c79d97cc
ToppCellParenchyma_Control_(B.)-Stromal-TX-Fibroblasts-1|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

USP53 SH3D19 NPNT

5.10e-04200353aa1a35dcca3b799241eef4237f6eb94660e019f0
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

USP53 SH3D19 NPNT

5.10e-04200353a510deaada669e690329183e18df02870bd204b3
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

USP53 SH3D19 NPNT

5.10e-04200353dd4228cbed8a4395166a6332e08d44d88bebe3b9
Disease3-methoxytyrosine measurement

RB1 DENND4C

3.93e-0427322EFO_0021009
Diseasecognitive function measurement, self reported educational attainment

TANC2 CACNA1E CLNK SH3D19

5.68e-04355324EFO_0004784, EFO_0008354
Diseasecup-to-disc ratio measurement

HELZ NPIPB15 PRDM16 NPNT

1.16e-03430324EFO_0006939
Diseaseidiopathic osteonecrosis of the femoral head

CUX2 CLNK

1.46e-0352322EFO_1001930
DiseaseSeizures

TANC2 CACNA1E CUX2

1.68e-03218323C0036572
DiseaseHETE measurement

HMGN2P46 GSE1

2.07e-0362322EFO_0801166
Diseasefasting blood insulin measurement

GLB1L3 KIF26B

2.55e-0369322EFO_0004466
DiseaseAntihypertensive use measurement

PCED1B PRDM16 NPNT

2.93e-03265323EFO_0009927
DiseaseS-7-hydroxywarfarin to S-warfarin ratio measurement

CUX2 GSE1

3.50e-0381322EFO_0803334
Diseasehypertension

CUX2 PRDM16 NPNT

4.42e-03307323EFO_0000537
Diseasesodium measurement

CUX2 GSE1

5.59e-03103322EFO_0009282
Diseasemean corpuscular hemoglobin concentration

CUX2 ELL2 EP400 MIDEAS PRDM16

6.34e-031105325EFO_0004528

Protein segments in the cluster

PeptideGeneStartEntry
APPSLRVPRPPPLYS

EP400

1841

Q96L91
AIPTPPPLPSTYLPI

ELL2

371

O00472
PVPPKPRPLLSYSSL

CACNA1E

2161

Q15878
YRPLPPLPIIDPPTE

ARHGEF5

836

Q12774
LKPGSPYRPPVPRAP

GSE1

706

Q14687
YVPRTLKPTVPPLTP

CUX2

871

O14529
PPTLSPIPHIPRSPY

RB1

776

P06400
PPKTPYIPPIITNRP

NPNT

296

Q6UXI9
PPKPTFRSYLLPPPQ

MTMR10

6

Q9NXD2
PLPRVPKLPPKAVYP

GLB1L3

396

Q8NCI6
PKLPPKAVYPPVRPS

GLB1L3

401

Q8NCI6
LLPSPYSKITPPRRP

KIF26B

1846

Q2KJY2
LYPEPTLVPTPPPEL

TMPRSS15

506

P98073
APLPSAYVPPLSLPP

HMGN2P46

56

Q86SG4
PALPLSPPLPSPTYR

PCED1B

286

Q96HM7
PGPYIALRSIPKLPP

POU5F2

101

Q8N7G0
YASALRAPPKPRPPP

HELZ

1896

P42694
YLLVPLPPSPLPPSV

NPIPB15

301

A6NHN6
TLAYFPPRPPLPPSV

SLC49A4

246

Q96SL1
SPPLPPYTPPTLKLR

CLCN5

736

P51795
KRPNPPPVSVPYLSP

DENND4C

1676

Q5VZ89
LPPYTPPPILSPVRE

MIDEAS

651

Q6PJG2
PLLRPPAYPGSLRPP

FIGNL2

411

A6NMB9
LLDKCPPPRPPTSPY

UTY

861

O14607
YPSAPLKPVTVPPRL

SH3D19

156

Q5HYK7
PPPVPKKPSVLYLPL

NHSL2

1001

Q5HYW2
GIFPPSLYPRPPLLP

PRDM16

516

Q9HAZ2
SLYPRPPLLPPTSLL

PRDM16

521

Q9HAZ2
KEYPSPPPSPLRRGP

TANC2

1526

Q9HCD6
LILSSRPKPSPPPPL

SPATA31D4

181

Q6ZUB0
RPSSLPILPSGPLYP

SHANK1

2016

Q9Y566
PPPRPLITLPKKYQP

CLNK

161

Q7Z7G1
PPPLPPKKYAITSVP

USP53

921

Q70EK8
LILSSRPKPSPPPPL

SPATA31D3

181

P0C874
LSPRPKASPPPPLIL

SPATA31D1

186

Q6ZQQ2
PSTLLPRPPFLYPGP

ZNF843

211

Q8N446
YALRLPRIPPPLPKP

PLAAT5

11

Q96KN8